Department of Medicine

Publications

Publications 2011

Chu, K.K., Tippayawat, P., Walker, N.J., Harding, S.V., Atkins, H.S., Maillere, B., Bancroft, G.J., Lertmemongkolchai, G., Altmann, D.M. CD4+ T-cell immunity to the Burkholderia pseudomallei ABC transporter LolC in melioidosis. Eur. J. Immunol. 2011; 41: doi; 10.1002/eji.201040881.

Coello, R., Brannigan, E., Lawson, W., Wickens, H., Holmes, A. Prevalence of healthcare device-associated infection using point prevalence surveys of antimicrobial prescribing and existing electronic data. Journal of Hospital Infection. 2011; doi: 10.1016/j.jhin.2011.01.028.

Dhesi, Z., Stebbing, J. The HVTN 503/Phambili study: efficacy is always the issue. The Lancet. 2011; DOI:10.1016/S1473-3099(11)70103-7.

Drumright, L.N., Holmes, A.H. Monitoring major illness in health care workers and hospital staff. Clinical Infectious Diseases. 2011; 53(3): 284-286.

Edwards, R., Drumright, L.N., Kiernan, M., Holmes, A. Covering more territory to fight resistance: considering nurses’ role in antimicrobial stewardship. Journal of Infection Prevention. 2011; 12(1): 6-10.

Edwards, R., Loveday, H., Drumright, L.N., Holmes, A. Should nurses be more involved in antimicrobial management? Journal of Infection Prevention. 2011; 12: (1). 4-5.

Elkington, P.T., D׳Armiento, J.M., Friedland, J.S. Tuberculosis immunopathology: The neglected role of extracellular matrix destruction. Science Translational Medicine. 2011; 3(71 71ps6): 1-4.

Elkington, P., Shiomi, T., Breen, R., Nuttall, R.K., Ugarte-Gil, C.A., Walker, N.F., Saraiva, L., Pedersen, B., Mauri, F., Lipman, M., Edwards, D.R., Robertson, B.D., D’Armiento, J., Friedland, J.S. MMP-1 drives immunopathology in human tuberculosis and transgenic mice. J Clin Invest. 2011; doi:10.1172/JCI45666.

Flower, B., Armstrong-James, D., Dance, C., Bremner, F., Doherty, T. Blind, breathless, and paralysed from benign malaria. The Lancet. 2011; 377 January 29: 438.

Green, J.A., Chau, T.T.H., Farrar, J.J., Friedland, J.S., Thwaites, G.E. CNS infection, CSF matrix metalloproteinase concentrations, and clinical/laboratory features. Neurology. 2011; 76: 577-579,

Haustein, T., Gastmeier, P., Holmes, A., Lucet, J.C., Shannon, R.P., Pittet, D., Harbarth, S. Use of benchmarking and public reporting for infection control in four high-income countries. The Lancet. 2011; 11: 471-480.

Jen, M.H., Saxena, S., Bottle, A., Aylin, P., Pollok, R. Increased health burden associated with Clostridium difficile diarrhoea in patients with inflammatory bowel disease. Alimentary Pharmacology and Therapeutics. 2011; 33(12): 1322-1331.

 

Publications 2010

Armstrong-James, D., Stebbing, J., John, L., Murungi, A., Bower, M., Gazzard, B., Nelson, M. A trial of caspofungin salvage treatment in PCP pneumonia. Thorax. 2010; doi: 10.1136/thx.2010.135350.

Armstrong-James, D., Teo, I.A., Shrivastava, S., Petrou, M.A., Taube, D., Dorling, A., Shaunak, S. Exogenous interferon-γ immunotherapy for invasive fungal infections in kidney transplant patients. American Journal of Transplantation. 2010; doi:10.1111/j.1600-6143.2010.03094.x.

Andreu, N., Zelmer, A., Fletcher, T., Elkington, P.T., Ward, T.H., Ripoll, J., Parish, T., Bancroft, G.J., Schaible, U., Robertson, B.D., Wiles, S. Optimisation of bioluminescent reporters for use with mycobacteria. PLoS ONE. 2010: 5(5): e10777. doi:10.1371/journal.pone.0010777.

Barata, T.S., Shaunak, S., Teo, I., Zloh, M., Brocchini, S. Structural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers. J Mol Model. 2010;. Doi: 10.1007/s00894-010-0907-1.

Charani, E., Cooke, J., Holmes, A. Antibiotic Stewardship programmes – what’s missing? J Antimicrob Chemother. 2010; doi:10.1093/jac/dlq357.

Cooke, J., Alexander, K., Charani, E., Hand, K., Hills, T., Howard, P., Jamieson, C., Lawson, W., Richardson, J., Wade, P. Antimicrobial stewardship: an evidence-based, antimicrobial self-assessment toolkit (ASAT) for acute hospitals. J. Antimicrob Chemother. 2010. doi:10.1093/jac/dkq367.

Corware, K.D., Rogers, M., Teo, I., Müller, I., Shaunak, S. An amphotericin B-based drug for treating experimental Leishmania major infection. Royal Society of Tropical Medicine and Hygiene. 2010; 104: 749-750. 

Elkington, P.T., Cooke, G.S. MMP12, Lung function, and COPD in high-risk populations. N Engl J Med. 2010; 362 (13): 1241-1241.

Fitzwater, S.P., Caviedes, L., Gilman, R.H., Coronel, J., LaChira, D., Salazar, C., Saravia, J.C., Reddy, K., Friedland, J.S., Moore, D.A.J. Prolonged infectiousness of tuberculosis patients in a directly observed therapy short-course program with standardized therapy. Clinical Infectious Diseases. 2010; 51(4): 371-378.

Green, J.A., Elkington, P.T., Pennington, C.J., Roncaroli, F., Dholakia, S., Moores, R.C., Bullen, A., Porter, J.C., Agranoff, D., Edwards, D.R., Friedland, J.S. Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-κB- and activator protein-1-dependent monocyte networks. Journal of Immunology. 2010; 184: 6492-6503. 

Ingram, R.J., Chu, K.K., Ketan, G., Maillere, B., Doganay, M., Ozkul, Y., Dyson, H., Williamson, E.D., Baillie, L., Kim, L.U., Ascough, S., Sriskandan, S., Altmann, D.M. An epitope of Bacillus anthracis protective antigen that is cryptic in rabbits may be immunodominant in humans. Infection and Immunity. 2010; 78(5): 2353-2354.

Ingram, R.J., Metan, G., Maillere, B., Doganay, M., Ozkul, Y., Kim, L.U., Baillie, L., Dyson, H., Williamson, E.D., Chu, K.K., Ascough, S., Moore, S., Huwar, T.B., Robinson, J.H., Sriskandan, S., Altmann, D.M. Natural exposure to cutaneous anthrax gives long-lasting T cell immunity encompassing infection-specific epitopes. Journal of Immunology. 2010; 184: 3814-3821.

Khamri, W., Walker, M.M., Clark, P., Atherton, J.C., Thursz, M.R., Bamford, K.B., Lechler, R.I., Lombardi, G. Helicobacter pylori stimulates dendritic cells to induce interleukin-17 expression from CD4+ T lymphocytes. Infection and Immunity. 2010; 78(2): 845-853.

Kotturi, M.F., Botten, J., Maybeno, M., Sidney, J., Glenn, J., Bui, H.H., Oseroff, C., Crotty, S., Peters, B., Grey, H., Altmann, D.M., Buchmeier, M.J., Sette, A. Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage. Immune Research. 2010; 6:4. doi:10.1186/1745-7580-6-4.

Kurupati, P., Turner, C.E., Tziona, I., Lawrenson, R.A., Alam, F.M., Nohadani, M., Stamp, G.W., Zinkernagel, A.S., Nizet, V., Edwards, R.J., Sriskandan, S. Chemokine-cleaving Streptococcus pyogenes protease SpyCEP is necessary and sufficient for bacterial dissemination within soft tissues and the respiratory tract. Molecular Microbiology. 2010; doi:10.1111/j.1365-2958.2010.07065.x

Oberhelman, R.A., Soto-Castellares, G., Gilman, R.H., Caviedes, L., Castillo, M.E., Kolevic, L., Del Pino, T., Saito, M., Salazar-Lindo, E., Negron, E., Montenegro, S., Laguna-Torres, V.A., Moore, D.A.J., Evans, C.A. Diagnostic approaches for paediatric tuberculosis by use of different specimen types, culture methods, and PCR: a prospective case-control study. The Lancet. 2020; 10: 612-620.  

O’Kane, C.M., Elkington, P.T., Jones, M.D., Caviedes, L., Tovar, M., Gilman, R.H., Stamp, G, Friedland, J.S. STAT3, p38 MAPK, and NF-κB drive unopposed monocyte-dependent fibroblast MMP-1 secretion in tuberculosis. Am J Respir Cell Mol Biol. 2010; 43: 465-474.

Read, P., Armstrong-James, D., Tong, C.Y.W., Fox, J. Missed opportunities for HIV testing – a costly oversight. Q J Med. 2010; doi: 10.1093/qjmed/hcq236.

Reddy, K.P., Brady, M.F., Gilman, R.H., Coronel, J., Ñavincopa, M., Ticona, E., Chavez, G,., Sánchez, E., Rojas, C., Solari, L., Valencia, J., Pinedo, Y., Benites, C., Friedland, J.S., Moore, D.A.J. Microscopic observation drug susceptibility assay for tuberculosis screening before isoniazid preventive therapy in HIV-infected persons. Clinical Infectious Diseases. 2010; 50: 988-996.

Sriskandan, S. Infectious Diseases. In: Sewell, C. (ed). First National Immunoglobulin Database Report (2008-2009). NHS, Department of Health. 2010. pp.47-49.

Uddin, J., Gonzalez, A.E., Gilman, R., Thomas, L.H., Rodriguez, S., Evans, C.A.W., Remick, D.G., Garcia, H.H., Friedland, J.S. Mechanisms regulating monocyte CXCL8 secretion in neurocysticercosis and the effect of antiparasitic therapy. Immunology. 2010; 185: 4478-4484.  

Wightman, F., Solomon, A., Khoury, G., Green, J.A., Gray, L., Gorry, P.R., Ho, Y.S., Saksena, N.K., Hoy, J., Crowe, S.M., Cameron, P.U., Lewin, S.R. Both CD31+ and CD31- naïve CD4+ T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy. The Journal of Infectious Diseases. 2010; 202(10): DOI: 10.1086/656721.  

Yuste, J., Sen, A., Truedsson, L., Jönsson, G., Hyams, C., Cohen, J.M., Camberlein, E., Sriskandan, S., Brown, J.S. Impaired opsonisation with complement and phagocytosis of Streptococcus pyogenes in sera from subjects with inherited C2 deficiency. Microbes and Infection. 2010: 12: 626-634.

 

Publications 2009

Altmann, D.M. Review series on helminths, immune modulation and the hygiene hypothesis: Nematode coevolution with adaptive immunity, regulatory networks and the growth of inflammatory diseases. Immunology. 2009; 126: (doi:10.1111/j.1365-2567.2008.03006.x).

Boyce, T., Murray, E., Holmes, A. What are the drivers of the UK media coverage of meticillin-resistant Staphylococcus aureus, the inter-relationships and relative influences? Journal of Hospital Infection. 2009; 73: 400-407.

Brannigan, E.T., Murray, E., Holmes, A. Where does infection control fit into a hospital management structure? Journal Hospital Infection. 2009; doi:10.1016/j,jhin.2009.03.031. 

Brown, C., Richards, M., Galletly, T., Coello, R., Lawson, W., Aylin, P., Holmes, A. Use of anti-infective serial prevalence studies to identify and monitor hospital-acquired infection. Journal of Hospital Infection. 2009; 73: 34-40.

Call, M.J., Xing, X., Cuny, G.D., Seth, N.P., Altmann, D.M., Fugger, L, Krogsgaard, M., Stein, R.L., Wucherpfennig, K.W. In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange. Journal of Immunology. 2009; 182: 6342-6352.

Campbell, J.D., Buckland, K.F., McMillan, S.J., Kearley, J. Oldfield, W.L.G., Stern, L.J., Grönlund, H., van Hage, M., Reynolds, C.J., Boyton, R.J., Cobbold, S.P., Kay, A.B., Altmann, D.M., Lloyd, C.M., Larché, M. Peptide Immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. J. Exp. Med. 2009; (doi:10.1084/jem.20082901. 

Elkington, P.T., Green, J.A., Friedland. J.S. Analysis of matrix metalloproteinase secretion by macrophages. Methods Mol Biol. 2009; 531: 253-265.  

Escombe, A.R., Moore, D.A.J., Gilman, R.H., Navincopa, M., Ticona, E., Mitchell, B., Noakes, C., Martinez, C., Sheen, P., Ramirez, R., Quino, W., Gonzalez, A., Friedland, J.S., Evans, C.A. Upper-room ultraviolet light and negative air ionization to prevent tuberculosis transmission. PLoS Medicine. 2009; 6(3): e43.

Friedland, J.S. Are you taking the lead? Royal College of Physicians. 2009; 9(4): 305-306.

Green, J.A., Tran, C.T.H., Farrar, J.J., Nguyen, M.T.H., Nguyen, P.H., Dinh, S.X., Ho, N.D.T., Ly, C.V., Tran, H.T., Friedland, J.S., Thwaites, G.E. Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis. PLoS ONE. 2009; 4(9): e7277.  

Handforth, J., Friedland, J.S., Sharland, M. Inhaled corticosteroids after respiratory syncytial virus infection. BMJ. 2009; 338: 963-964.

Hargreaves, S., Carballo, M., Friedland, J.S. Screening Migrants for tuberculosis: where next? The Lancet. 2009; 9: 139-140.

Ingram, R.J., Isaacs, J.D., Kaur, G., Lowther, D.E., Reynolds, C.J., Boyton, R.J., Collinge, J., Jackson, G.S., Altmann, D.M. A role of cellular prion protein in programming T-cell cytokine responses in disease. The FASEB Journal. 2009; (doi:10.1096/fj.08-116087).

Kaushansky, N., Altmann, D.M., Ascough, S., David, C.S., Lassmann, H., Ben-Nun, A. HLA-DQB1*0602 determines disease susceptibility in a new “Humanized” multiple sclerosis model in HLA-DR15 (DRB1*1501;DQB1*0602) transgenic mice. Journal of Immunology. 2009; 183: 3531-3541.  

Lalwani, S., Chouai, A., Perez, L.M., Santiago, V., Shaunak, S., Simanek, E.E. Mimicking PAMAM dendrimers with amphoteric, hybrid triazine dendrimers: A comparison of dispersity and stability. Macromolecules. 2009; 42: 6723-6732.           

Lalwani, S., Venditto, V.J., Chouai, A., Rivera, G.E., Shaunak, S., Simanek, E.E. Electrophoretic behaviour of anionic triazine and PAMAM dendrimers: Methods for improving resolution and assessing purity using capillary electrophoresis. Macromolecules. 2009; 42: 3152-3161.

Lambourne, J., Agranoff, D., Herbrecht, R., Troke, P.F., Buchbinder, A., Willis, F., Letscher-Bru, V., Agrawal, S., Doffman, S., Johnson, E., Lewis White, P., Barnes, R.A., Griffin, G., Lindsay, J.A., Harrison, T.S. Association of mannose-binding lectin deficiency with acute invasive aspergillosis in immunocompromised patients. Clinical Infectious Diseases. 2009; 49: 1486-1491.

Modi, N., Doré, C.J., Saraswatula, A., Richards, M., Bamford, K.B., Coello, R, Holmes, A. A case definition for national and international neonatal bloodstream infection surveillance. Arch Dis Child Fetal Neonatal Ed. 2009; 94: F8-F12. doi:10.1136/adc.2007.126458.

Rand, L., Green, J.A., Saraiva, L., Friedland, J.S., Elkington, P.T. Matrix metalloproteinase-1 is regulated in tuberculosis by a p38 MAPK-Dependent, p-Aminosalicylic acid-sensitive signaling cascade. The Journal of Immunology. 2009; 182: 5865-5872.  

Read, R.C., Friedland, J.S. 30 years on; the continuing evolution of our journal and our society. British Infection Society. 2009; 58: (doi.10.1016/j.jinf.2008.12011). 

Reynolds, C., Barkans, J., Clark, P., Kariyawasam, H., Altmann, D., Kay, B., Boyton, R. Natural killer T cells in bronchial biopsies from human allergen challenge model of allergic asthma. J Allergy Clin Immunol. 2009; doi:10.1016.j.jaci.2009.07.022. 

Russell, H.H., Zhou, L., Sriskandan, S. Rapid screen for epithelial internalization of Tn917-mutagenized Streptococcus pyogenes. Journal of Microbiological Methods. 2009; 78: 34-39.

Sheen, P., O’Kane, C.M., Chaudhary, K., Tovar, M., Santillan, C., Sosa, J., Caviedes, L., Gilman, R.H., Stamp, G., Friedland, J.S. High MMP-9 activity characterises pleural tuberculosis correlating with granuloma formation. Eur Respir J. 2009; 33: 134-141.

Turner, C.E., Kurupati, P., Jones, M.D., Edwards, R.J., Sriskandan, S. Emerging role of the Interleukin-8 cleaving enzyme SpyCEP in clinical Streptococcus pyogenes infection. Journal of Infectious Diseases. 2009; 200: 555-563.

Turner, C.E., Kurupati, P., Wiles, S., Edwards, R.J., Sriskandan, S. Impact of immunization against SpyCEP during invasive disease with two streptococcal species: Streptococcus pyogenes and Streptococcus equi. Vaccine. 2009; doi:10.1016/j.vaccine.2009.06.042.

Williams, I., Ahmed, I., Friedland, J.S., Fisher, M., Ong, E., Palfreeman, A. HIV testing in the UK. The Lancet. 2009; 374: 376.

Zota, V., Nemirovsky, A., Baron, R., Fisher, Y., Selkoe, D.J., Altmann, D.M., Weiner, H.L., Monsonego, A. HLA-DR alleles in amyloid β-peptide autoimmunity: A highly immunogenic role for the DRB1*1501 allele1. Journal of Immunology. 2009; 183: 3522-3530.

 

Publications 2008

Agranoff, D. The science behind the screening. Public Service Review. 2008; 14: 49-50.

Beck, A.L., Cabrera, L., Pan, W.K., Cama, V., Friedland, J.S., Ghatel, M.A., Bloom, S.R., Lewis, J., Gilman, R.H. Peptide YY: a gut hormone associated with anorexia during infectious diarrhoea in children. J. Pediatr. 2008; 153: 677-682. 

Boyton, R.J., Smith, J., Jones, M., Reynolds, C., Ozerovitch, L., Chaudhry, A., Wilson, R., Rose, M., Altmann, D.M. Human leucocyte antigen class II associated in idiopathic bronchiectasis, a disease of chronic lung disease infection, implicates a role for adaptive immunity. Clinical and Experimental Immunology. 2008; 152(1): 95-101.

Brocchini, S., Godwin, A., Balan, S., Choi, J.W., Zloh, M., Shaunak, S. Disulfide bridge based PEGylation of proteins. Science Direct. 2008; 60: 3-12.

Escombe, A.R., Moore, D.A.J., Gilman, R.H., Pan, W., Navincopa, M., Ticona, E., Martinez, C., Caviedes, L., Sheen, P., Gonzalez, A., Noakes, C.J., Friedland, J.S., Evans, C.A. The infectiousness of infectious tuberculosis patients coinfected with HIV. PLos Med. 5(9): e188.

Friedland, J.S. Tackling tissue destruction in tuberculosis. Trans. R. Soc. Trop. Med. Hyg. 2008; 201: 953-954.

Hargreaves, S. UK team adopts unique approach to hospital infection control. The Lancet. 2008; 8(12): 747.

Hargreaves, S., Holmes, A.H., Saxena, S., Le Feuvre, P., Farah, W., Shafi, G., Chaudry, J., Khan, H., Friedland, J.S. Charging systems for migrants in primary care: The experiences of family doctors in a high-migrant area of London. J. Travel Med. 2008; 15 (1): 13-18.

Harris, J.E., Friedland, J.S. L-glutamate in Middlebrook 7H9 culture medium upregulates matrix metalloproteinase-2 secretion from human astrocytoma cells. J. Neurosci. Methods. 2008; 173: 291-294.

Holmes, A. An organisation approach to infection prevention. The Bulletin of the Royal College of Pathologists. 2008; 142: 106-110.

Holmes, A., Doré, C.J., Saraswatula, A., Bamford, K.B., Richards, M.S., Coello, R., Modi, N. Risk factors and recommendations for rate stratification for surveillance of neonatal healthcare-associated bloodstream infection. Journal of Hospital Infection. 2008, 68: 66-72.

Hopkins, P.A., Pridmore, A.C., Ellmerich, S., Fraser, J.D., Russell, H.H., Read, R.C., Sriskandan, S. Increased surface toll-like receptor 2 expression in superantigen shock. Crit Care Med. 2008; 36(4): 1267-1276.

Isaacs, J.D., Garden, O.A., Kaur, G., Collinge, J., Jackson, G.S., Altmann, D.M. The cellular prion protein is preferentially expressed by CD4+ CD25+ Foxp3+ regulatory T cells. Immunology. 2008; 125: 313-319.

Issa, R., Sorrentino, R., Sukkar, M.B., Sriskandan, S., Chung, K.F., Mitchell, J.A. Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells. Respir Res. 2008; 9: 30.

Jen, M.H., Holmes, A.H., Bottle, A., Aylin, P. Descriptive study of selected healthcare-associated infections using national Hospital Episode Statistics data 1996 – 2006 and comparison with mandatory reporting systems. Journal of Hospital Infection. 2008; 70: 321-327.

McMaster, S.K., Paul-Clark, M.J., Walters, M., Fleet, M., Anandarajah, J., Sriskandan, S., Mitchell, J.A. Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress. Br J Pharmacol. 2008: 153(3): 536-543.

Morrison, P.T., Sharland, M., Thomas, L.H., Manna, S., Handforth, J., Tibby, S., Friedland, J.S. Chemokine receptor upregulation and disease severity in Respiratory Syncytial Virus infection. Clin. Immunol. 2008; 128: 85-93.

O’Kane, C.M., Elkington, P.T., Friedland, J.S. Monocyte-dependent oncostatin M and TNF-α synergize to stimulate unopposed matrix metalloproteinase-1/3 secretion from human lung fibroblasts in tuberculosis. Eur. J. Immunol. 2008; 38: 1321-1330.

Paul-Clark, M.J., Sorrentino, R., Bailey, L.K., Sriskandan, S., Mitchell, J.A. Gram-positive and Gram-negative bacteria synergize with oxidants to release CXCL8 from innate immune cells. Mol Med. 2008; 14(5-6): 238-246.

Rojas-Galeano, S., Hsieh, E., Agranoff, D., Krishna, S., Fernandez-Reyes, D. Estimation of relevant variables on high-dimensional biological patterns using iterated weighted kernel functions. PLoS ONE. 2008; 3 (3): e1806. 

Russell, H.H., Sriskandan, S. Superantigens SPEA and SMEZ do not affect secretome expression in Streptococcus pyogenes. Microbial Pathogenesis. 2008; 44(6): 537-543.

Sadiq, S.T., Agranoff, D. Pooling serum samples may lead to loss of potential biomarkers in SELDI-ToF MS proteomic profiling. Proteome Science. 2008; 6:16. doi;10.1186/1477-5956-6-16.  

Sheen, P., O’Kane, C.M., Chaudhary, K., Tovar, M., Santillan, C., Sosa, J., Caviedes, L., Gilman, R.H., Stamp, G., Friedland, J.S. High MMP-9 activity characterizes pleural tuberculosis correlating with granuloma formation. Eur. Respir. J. 2008; 33: 134-141.

Shovlin, C.L., Bamford, K.B., Wray, D. Post-NICE 2008: antibiotic prophylaxis prior to dental procedures for patients with pulmonary arteriovenous malformations (PAVMs) and hereditary haemorrhagic telangiectasia. British Dental Journal. 2008; 205: 531-533. 

Shovlin, C.L., Jackson, J.E., Bamford, K.B., Jenkins, I.H., Benjamin, A.R., Ramadan, H., Kulinskaya, E. Primary determinants of ischaemic stroke/brain abscess risks are independent of severity of pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia. Thorax. 2008; 63: 259-266.

Sorrentino R., de Souza, P.M., Sriskandan, S., Duffin, C., Paul-Clark, M.J., Mitchell, J.A. Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function. Br J Pharmacol. 2008; 154(4): 864-871.

Sriskandan, S., Altmann, D.M. The immunology of sepsis. Journal of Pathology. 2008; 214: 211-223.

Vincent, C., Aylin, P., Franklin, B.D., Holmes, A., Iskander, S., Jacklin, A., Moorthy, K. Is health care getting safer? BMJ. 2008; 337: 1205-1207.

Wakerley, B., Nicholas, R., Malik, O. Multiple sclerosis. Medicine. 2008; 36:12. 625-629.

Walters, J.R.F., Bamford, K.B., Ghosh, S. Coeliac disease and the risk of infections. Gut. 2008; 57 (8): 1034-1035.

Zinkernagel, A.S., Timmer, A.M., Pence, M.A., Locke, J.B., Buchanan, J.T., Turner, C.E., Mishalian, I., Sriskandan, S., Hanski, E., Nizet, V. The IL-8 protease SpyCEP/ScpC of Group A Streptococcus promotes resistance to neutrophil killing. Cell Host & Microbe.  2008; 4: 170-178.  


 

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