The UK-CRC-funded National Centre for Infection Prevention and Management (CIPM) is tackling the issue of healthcare acquired infection via a multidisciplinary approach that includes organisational research, social marketing, epidemiology, laboratory-based programmes and education. The initiative, funded for 5 years, includes the creation of 13 new posts and 7 studentships and involves collaborations with Public Health England (PHE) as well as across the Faculty of Medicine, Faculty of Life Sciences and the Business School. The Centre has 4 main themes or work-streams, as outlined below with a number of projects in each area.
Work-stream one of four is in two parts both of which address the implementation gap between research and its use in the NHS. Part A of the work-stream will examine the factors which prevent or hinder the adoption of new technologies, behaviours or patterns of working within the NHS. Using institutional theory this work-stream will deliver guidelines and briefs on how to diagnose such factors. Part B will examine the effectiveness and sustainability of using Social Marketing in changing behaviours relevant to infection control and antibiotic prescribing.
Work-stream 2 establishes a network in clinical infection, molecular epidemiology and pathogenesis to improve diagnostics and management. Through its laboratory programme and collaboration with the Centre for Infections, PHE, this stream will identify whether some features of Staphylococcus aureus, Streptococcus pyogenes, and Clostridium difficile strains make them more invasive and transmissible than others. Targeting of identified strains via rapid diagnostics will allow appropriate management and prevention strategies to be undertaken, building on information gleaned from the molecular pathogenesis studies.
Work-stream three will use existing databases within Imperial College Healthcare NHS Trust, the NHS, PHE and elsewhere to develop predictive models which will enable identification of at risk patients and effectively direct early intervention. This work-stream will also evaluate systems to monitor antibiotic resistance and prescribing practice which will provide information about front line antibiotic management decisions in support of antimicrobial policies.
Work-stream four will develop a range of educational courses and training. These will aim to develop a specifically skilled academic, clinical scientific and medical workforce to deliver clinical care, research and leadership in infection prevention. Working with the PHE regional laboratories, a number of National Infection Prevention courses for microbiologists and infectious disease doctors in training will be developed. Other new multiprofessional training will be developed for allied health professionals according to assessed need and demand.