For:

DDC Survey: Inflammatory & Autoimmune mechanisms of disease

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Imperial College London, South Kensington Campus, London SW7 2AZ tel: +44 (0)20 7589 5111
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* Project Title

* Therapeutic aim

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What is the molecular nature of your target?	enzyme receptor pathway other unknown

Is there structural information available on the target?	yes: crystal structure yes: NMR data yes: other no: but model no

What target validation data do you have?	siRNA data in vitro knock out in vivo knock out clinical distribution target modulation: compound target modulation: antibody target modulation: other other § none

Are there any working assays available?	yes: biochemical assay yes: cellular assay no

Do you have any small molecules/tool compounds on this project?	yes no

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