Dr Keith Gould
Antigen Presentation by MHC Class I Molecules
Dr Gould is a Senior Lecturer in the Section of Immunology at the St Mary's campus, and has been a Principal Investigator at Imperial College London since 1996. The theme of Dr Gould's research is antigen presentation by major histocompatibility complex (MHC) class I molecules, and in particular the biochemistry and cell biology of these molecules. Recently, we have developed the use of single chain MHC class I molecules, in which the three normally separate components of a class I molecule are joined together via flexible linker sequences. These single chain molecules have a number of important advantages, and are being exploited for various purposes. This research would be directly relevant to the clinical speciality of immunology, and is also relevant to microbiology and cancer.
In addition to research activities, Dr Gould plays a significant role in teaching. He is Leader for the Theme "Molecules, Cells and Disease" in years 1 and 2 of Undergraduate Medicine, and is Co-ordinator for School 3 of the Wellcome Trust MRes Course "Molecular and Cellular Basis of Infection". Dr Gould was given an Imperial College Award for Excellence in Teaching in both 2002 and 2007.
Further information: http://www1.imperial.ac.uk/medicine/people/k.gould/
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