Professor Waljit Dhillo

Endocrinology - Obesity and metabolism

Endocrine function and nutritional status are tightly regulated through common pathways in order that individuals will only be able to reproduce if sufficient nutrients are available. Abnormalities in the regulation of these pathways commonly results in infertility. However the neuropeptides, hormones and neuronal circuits which regulate these important pathways remain largely unknown.  Our group have recently identified novel hypothalamic regulators which are vital in the metabolic control of reproductive function. Using animal models as well as ‘first into human’ studies our work has identified the prokineticin peptides (http://www.sciencedaily.com/releases/2009/06/090610091228.htm) in the metabolic regulation of fertility and the key role of kisspeptin (http://news.bbc.co.uk/1/hi/health/7945600.stm) as a novel therapy for infertility.

The clinical specialty relevant to: Medicine, endocrinology, diabetes and metabolism.

Further Information
www.hammersmithendocrinology.co.uk

Contact Details
w.dhillo@imperial.ac.uk
Tel: +44 (0)20 8383 2820