Research

External collaborations

COST Project B15 on Modelling During Drug Development, UK Representative and vice-chairman.

International Life Sciences Institute, Health and Environment Sciences Institute, Member of Board of Trustees.

International Life Sciences Intitute, Europe, Risk-Benefit Working Group, chair.

International Life Sciences Institute, Health and Environmental Sciences Institute, Agrochemical Safety Assessememt Committee.

Academy of Medical Sciences, Steering Committee on "Towards Better Safety Assessment of Medicical Products".

ILSI Europe, Workshop: Structure-based thresholds of toxicological concern: Guidance for application to substances present at low levels in the diet, for chemical substances.

Fellowships

British Toxicology Society, FIBT. 2006 -

Institute of Biology, FIBiol. 1991 -

Guest lectures

Homeostasis and repair following exposure to toxicants. Sixth Nordic Conference, Nordtox 2001, Beito, Norway. 27 Jan 2001.

Discussant. ECVAM-ERGATT Workshop on Prediction of Systemic Toxicity of Chemicals, Angerra, Italy. 12 Feb 2001.

Genetic variation in the human population. HSE Workshop on Variability and Susceptibility in Human Response to Occupational Exposure to Chemicals in the UK, Leicester. Feb 2001.

Chairman. BTS/HSL Workshop on PBPK Modelling, Sheffield. Mar 2001.

In Vitro prediction of drug metabolism and interactions: Experience of a European collaboration (EUROCYP). UK Drug Metabolism Group Meeting, Loughbrough. Apr 2001.

Biochemical clearance mechanisms in the lung. DERA/BALR Meeting on Lung Deposition and Clearance, Porton Down. May 2001.

In vitro prediction of the specificity of drug metabolism. 51st Czech and Slovak Pharmacology Society Meeting, Hradec Kralove, Czech Republic. 5 Sep 2001.

Introduction and chair of symposium on Proteomics and Adverse Drug Reactions. European Congress on Toxicology, EUOTOX 2001, Istanbul, Turkey. 12 Sep 2001.

Differential stability of P450 enzymes. Annual PKUK meeting, Cardiff. 7 Nov 2001.

Prediction of drug metabolism. Society of the Chemical Industry Symposium on ADME: Perspectives in High Throughput and In Silico Approaches, London.. 4 Dec 2001.

Chairman of Symposium on Mixture of Chemicals: What are the Implications for Regulators. Annual Congress of the British Toxicology Society, University of Kent, Canterbury. 7 Apr 2002.

Factors affecting bioactivation. Fifth Balkan Workshop on Drug Metabolism and Toxicity, Constanta, Romania. 29 May 2002.

Interactions of antibiotics with the p450 system: implications for drug metabolism. International Conference On Antimicrobial Agents In Veterinary Medicine (AAVM), Helsinki, Finland. 4 Aug 2002.

Validation of screening methods for in vitro and in silico drug methods for drug metabolism. EUFEPS Congress, Stockholm. 21 Oct 2002.

Discussant. International Symposium on Agricultural Exposures and Cancer, Green College, Oxford. 19 Nov 2002.

Chairman. Joint FAO/WHO Workshop on the Project to Update the Principles and Methods for the Risk Assessment of Chemicals in Food, Food Standards Agency, London. 9 Dec 2002.

Prediction of metabolism: Case study using METEOR. Molecular Graphics Modelling Society Meeting: Computational Approaches to the Understanding of ADMET Properties and Problems,Oxford. 2 Apr 2003.

Toxicological mechanisms: Review of ongoing research and future needs. ESF Meeting on “An Environment for Better Health”, Aarhus, Denmark. 8 May 2003.

Heterocyclic amines: Hazard – yes; Risk - ?. Symposium in honour of Prof Erik Dybing, Oslo, Norway. 1 Jun 2003.

Rational risk assessment in a changing world. Meeting on Use of Toxicogenomics in Risk Assessment, Occupational and Environmental Toxicology Group of the Royal Society of Chemistry, London.. 5 Sep 2003.

Chronic health effects from pesticide exposure. 4th Congress of Toxicology in Developing Countries, Guilin, China.. 10 Nov 2003.

Selection of test set of compounds for validation of metabolism. COST Action B15 Expert Meeting on Validation of In Silico Methods for Prediction of Absorption and Metabolism, Brussels. 2 Apr 2004.