Professor Andrew J T George

Publications


Journals

  • Lin W; Oh SKW; Choo ABH; George AJT. (1 Jan 2012). Activated T cells modulate immunosuppression by embryonic- and bone marrow-derived mesenchymal stromal cells through a feedback mechanism. CYTOTHERAPY. 14:274-284. DOI.
  • Kamperidis P; Kamalati T; Ferrari M; Jones M; Garrood T; Smith MD; Diez-Posada S; Hughes C; et alFinucane C; Mather S; Nissim A; George AJT; Pitzalis C. (1 Dec 2011). Development of a novel recombinant biotherapeutic with applications in targeted therapy of human arthritis. ARTHRITIS AND RHEUMATISM. 63:3758-3767. Author weblink DOI.
  • Leyton J; Iddon L; Perumal M; Indrevoll B; Glaser M; Robins E; George AJ; Cuthbertson A; et alLuthra SK; Aboagye EO. (Sep 2011). Targeting somatostatin receptors: preclinical evaluation of novel 18F-fluoroethyltriazole-Tyr3-octreotate analogs for PET. J Nucl Med. 52:1441-1448. DOI.
  • Fu H; Khan A; Coe D; Zaher S; Chai JG; Kropf P; Müller I; Larkin DF; et alGeorge AJ. (Oct 2011). Arginine depletion as a mechanism for the immune privilege of corneal allografts. Eur J Immunol. 41:2997-3005. DOI.
  • Iddon L; Leyton J; Indrevoll B; Glaser M; Robins EG; George AJ; Cuthbertson A; Luthra SK; et alAboagye EO. (15 May 2011). Synthesis and in vitro evaluation of [18F]fluoroethyl triazole labelled [Tyr3]octreotate analogues using click chemistry. Bioorg Med Chem Lett. 21:3122-3127. DOI.
  • Zaher SS; Germain C; Fu H; Larkin DF; George AJ. (Apr 2011). 3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci. 52:2640-2648. DOI.
  • Seow WY; Yang Y-Y; George AJT. (1 Jul 2010). Novel Triblock Oligopeptides as Efficient Nonviral Vectors: Characterisation and Further Insights. MACROMOLECULAR RAPID COMMUNICATIONS. 31:1170-1174. DOI.
  • Mouratidis PX; George AJ. (2010). Transfection of indoleamine 2,3 dioxygenase in primary endothelial cells. Methods Mol Biol. 616:149-159. DOI.
  • Hansel TT; Kropshofer H; Singer T; Mitchell JA; George AJ. (Apr 2010). The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov. 9:325-338. DOI.
  • Seow WY; Yang YY; George AJ. (Oct 2009). Oligopeptide-mediated gene transfer into mouse corneal endothelial cells: expression, design optimization, uptake mechanism and nuclear localization. Nucleic Acids Res. 37:6276-6289. DOI.
  • Fazekasova H; Golshayan D; Read J; Tsallios A; Tsang JY-S; Dorling A; George AJT; Lechler RI; et alLombardi G; Mirenda V. (15 Jun 2009). Regulation of Rat and Human T-Cell Immune Response by Pharmacologically Modified Dendritic Cells. TRANSPLANTATION. 87:1617-1628. Author weblink DOI.
  • Theoharis S; Krueger U; Tan PH; Haskard DO; Weber M; George AJT. (15 Apr 2009). Targeting gene delivery to activated vascular endothelium using anti E/P-Selectin antibody linked to PAMAM dendrimers. JOURNAL OF IMMUNOLOGICAL METHODS. 343:79-90. DOI.
  • Fu H; Larkin DF; George AJ. (Apr 2008). Immune modulation in corneal transplantation. Transplant Rev (Orlando). 22:105-115. DOI.
  • Pillai RG; Beutelspacher SC; Larkin DFP; George AJT. (15 Jun 2008). Expression of the chemokine antagonist vMIP II using a non-viral vector can prolong corneal allograft survival. TRANSPLANTATION. 85:1640-1647. Author weblink DOI.
  • Pillai RG; Beutelspacher SC; Larkin DF; George AJ. (Feb 2008). Upregulation of chemokine expression in murine cornea due to mechanical trauma or endotoxin. Br J Ophthalmol. 92:259-264. DOI.
  • Tamir A; Basagila E; Kagahzian A; Jiao L; Jensen S; Nicholls J; Tate P; Stamp G; et alFarzaneh F; Harrison P; Stauss H; George AJ; Habib N; Lechler RI; Lombardi G. (Dec 2007). Induction of tumor-specific T-cell responses by vaccination with tumor lysate-loaded dendritic cells in colorectal cancer patients with carcinoembryonic-antigen positive tumors. Cancer Immunol Immunother. 56:2003-2016. DOI.
  • Soleimani B; Wieczorek G; Katopodis A; Zenke G; George AJT; Hornick PI; Weitz-Schmidt G. (1 Jul 2007). Anti-LFA-1 monotherapy prevents neointimal formation in a murine model of transplant intimal hyperplasia. JOURNAL OF HEART AND LUNG TRANSPLANTATION. 26:724-731. Author weblink DOI.
  • Chan C; George AJT; Stark J. (1 Jul 2007). Cytotoxic killing and immune evasion by repair. JOURNAL OF STATISTICAL PHYSICS. 128:393-411. Author weblink DOI.
  • Yates A; Chan C; Strid J; Moon S; Callard R; George AJT; Stark J. (12 Jun 2007). Reconstruction of cell population dynamics using CFSE. BMC BIOINFORMATICS. 8. Author weblink DOI.
  • Stark J; Chan C; George AJ. (Apr 2007). Oscillations in the immune system. Immunol Rev. 216:213-231. DOI.
  • Tan PH; Xue S-A; Wei B; Holler A; Voss R-H; George AJT. (1 Mar 2007). Changing viral tropism using immunoliposomes alters the stability of gene expression: Implications for viral vector design. MOLECULAR MEDICINE. 13:216-226. Author weblink DOI.
  • Soleimani B; Katopodis A; Wieczorek G; George AJ; Hornick PI; Heusser C. (Dec 2006). Smooth muscle cell proliferation but not neointimal formation is dependent on alloantibody in a murine model of intimal hyperplasia. Clin Exp Immunol. 146:509-517. DOI.
  • George AJT; Bhakoo KK; Haskard DO; Larkman DJ; Reynolds PR. (15 Nov 2006). Imaging molecular and cellular events in transplantation. TRANSPLANTATION. 82:1124-1129. Author weblink DOI.
  • Reynolds PR; Larkman DJ; Haskard DO; Hajnal JV; Kennea NL; George AJT; Edwards AD. (1 Nov 2006). Detection of vascular expression of e-selectin in vivo with MR imaging. RADIOLOGY. 241:469-476. Author weblink DOI.
  • Alam AKMS; Florey O; Weber M; Pillai RG; Chan C; Tan PH; Lechler RI; McClure MO; et alHaskard DO; George AJT. (1 Nov 2006). Knockdown of mouse VCAM-1 by vector-based siRNA. TRANSPLANT IMMUNOLOGY. 16:185-193. DOI.
  • Buckland M; Jago CB; Fazekasova H; Scott K; Tan PH; George AJT; Lechler R; Lombardi G. (1 Sep 2006). Aspirin-treated human DCs up-regulate ILT-3 and induce hyporesponsiveness and regulatory activity in responder T cells. AMERICAN JOURNAL OF TRANSPLANTATION. 6:2046-2059. Author weblink DOI.
  • Watson MP; George AJ; Larkin DF. (Aug 2006). Differential effects of costimulatory pathway modulation on corneal allograft survival. Invest Ophthalmol Vis Sci. 47:3417-3422. DOI.
  • Tan PH; George AJ; Handa AI. (Aug 2006). Gene therapy for clinical transplantation: where do we stand in 2006?. Discov Med. 6:153-156.
  • Tan PH; Tan PL; George AJ; Chan CL. (Aug 2006). Gene therapy for transplantation with viral vectors--how much of the promise has been realised?. Expert Opin Biol Ther. 6:759-772. DOI.
  • Soleimani B; Lechler RI; Hornick PI; George AJ. (Aug 2006). Role of alloantibodies in the pathogenesis of graft arteriosclerosis in cardiac transplantation. Am J Transplant. 6:1781-1785. DOI.
  • Garden OA; Reynolds PR; Yates J; Larkman DJ; Marelli-Berg FM; Haskard DO; Edwards AD; George AJ. (31 Jul 2006). A rapid method for labelling CD4+ T cells with ultrasmall paramagnetic iron oxide nanoparticles for magnetic resonance imaging that preserves proliferative, regulatory and migratory behaviour in vitro. J Immunol Methods. 314:123-133. DOI.
  • Manunta M; Nichols BJ; Tan PH; Sagoo P; Harper J; George AJ. (31 Jul 2006). Gene delivery by dendrimers operates via different pathways in different cells, but is enhanced by the presence of caveolin. J Immunol Methods. 314:134-146. DOI.
  • Beutelspacher SC; Tan PH; McClure MO; Larkin DF; Lechler RI; George AJ. (Jun 2006). Expression of indoleamine 2,3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponses. Am J Transplant. 6:1320-1330. DOI.
  • Tan PH; Chan CL; George AJ. (Jun 2006). Strategies to improve non-viral vectors--potential applications in clinical transplantation. Expert Opin Biol Ther. 6:619-630. DOI.
  • Tan PH; Xue SA; Manunta M; Beutelspacher SC; Fazekasova H; Alam AK; McClure MO; George AJ. (Mar 2006). Effect of vectors on human endothelial cell signal transduction: implications for cardiovascular gene therapy. Arterioscler Thromb Vasc Biol. 26:462-467. DOI.
  • Beutelspacher SC; Pillai R; Watson MP; Tan PH; Tsang J; McClure MO; George AJ; Larkin DF. (Mar 2006). Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression. Eur J Immunol. 36:690-700. DOI.
  • Kodama T; Tan PH; Offiah I; Partridge T; Cook T; George AJT; Blomley MJK. (1 Dec 2005). Delivery of oligodeoxynucleotides into human saphenous veins and the adjunct effect of ultrasound and microbubbles. ULTRASOUND IN MEDICINE AND BIOLOGY. 31:1683-1691. Author weblink DOI.
  • Tan PH; Chan CLH; Chan C; George AJT. (1 Dec 2005). The evolving role of gene-based treatment in surgery. BRITISH JOURNAL OF SURGERY. 92:1466-1480. Author weblink DOI.
  • Chan C; Stark J; George AJT. (1 Dec 2005). The impact of multiple T cell-APC encounters and the role of anergy. JOURNAL OF COMPUTATIONAL AND APPLIED MATHEMATICS. 184:101-120. Author weblink DOI.
  • George AJ; Stark J; Chan C. (Dec 2005). Understanding specificity and sensitivity of T-cell recognition. Trends Immunol. 26:653-659. DOI.
  • Tan PH; Yates JB; Xue SA; Chan C; Jordan WJ; Harper JE; Watson MP; Dong R; et alRitter MA; Lechler RI; Lombardi G; George AJ. (1 Nov 2005). Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression. Blood. 106:2936-2943. DOI.
  • Mirenda V; Millington O; Lechler RI; Scott D; Hernandez-Fuentes MP; Read J; Tan PH; George AJ; et alGarside P; Marelli-Berg FM. (Jul 2005). Tolerant T cells display impaired trafficking ability. Eur J Immunol. 35:2146-2156. DOI.
  • Tan PH; Sagoo P; Chan C; Yates JB; Campbell J; Beutelspacher SC; Foxwell BM; Lombardi G; et alGeorge AJ. (15 Jun 2005). Inhibition of NF-kappa B and oxidative pathways in human dendritic cells by antioxidative vitamins generates regulatory T cells. J Immunol. 174:7633-7644.
  • Beutelspacher SC; Ardjomand N; Tan PH; Patton GS; Larkin DF; George AJ; McClure MO. (Jun 2005). Comparison of HIV-1 and EIAV-based lentiviral vectors in corneal transduction. Exp Eye Res. 80:787-794. DOI.
  • Tan PH; Beutelspacher SC; Xue SA; Wang YH; Mitchell P; McAlister JC; Larkin DF; McClure MO; et alStauss HJ; Ritter MA; Lombardi G; George AJ. (15 May 2005). Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy. Blood. 105:3824-3832. DOI.
  • Tan PH; Beutelspacher SC; Wang YH; McClure MO; Ritter MA; Lombardi G; George AJ. (May 2005). Immunolipoplexes: an efficient, nonviral alternative for transfection of human dendritic cells with potential for clinical vaccination. Mol Ther. 11:790-800. DOI.
  • George AJ. (Feb 2005). Dendritic cells in cancer immunotherapy. 10 January 2005, London, UK. IDrugs. 8:104-106.
  • Sagoo P; Chan G; Larkin DF; George AJ. (Nov 2004). Inflammatory cytokines induce apoptosis of corneal endothelium through nitric oxide. Invest Ophthalmol Vis Sci. 45:3964-3973. DOI.
  • George AJ. (Nov 2004). Transplantation Society--XXth International Congress. 5-10 September 2004, Vienna, Austria. IDrugs. 7:984-986.
  • Nicholson S; Bomphray CC; Thomas H; McIndoe A; Barton D; Gore M; George AJ. (Sep 2004). A phase I trial of idiotypic vaccination with HMFG1 in ovarian cancer. Cancer Immunol Immunother. 53:809-816. DOI.
  • Fraser SP; Diss JK; Lloyd LJ; Pani F; Chioni AM; George AJ; Djamgoz MB. (2 Jul 2004). T-lymphocyte invasiveness: control by voltage-gated Na+ channel activity. FEBS Lett. 569:191-194. DOI.
  • Chan C; Stark J; George AJ. (7 May 2004). Feedback control of T-cell receptor activation. Proc Biol Sci. 271:931-939. DOI.
  • George AJ; Larkin DF. (May 2004). Corneal transplantation: the forgotten graft. Am J Transplant. 4:678-685. DOI.
  • Tan PH; Chan C; Xue SA; Dong R; Ananthesayanan B; Manunta M; Kerouedan C; Cheshire NJ; et alWolfe JH; Haskard DO; Taylor KM; George AJ. (Apr 2004). Phenotypic and functional differences between human saphenous vein (HSVEC) and umbilical vein (HUVEC) endothelial cells. Atherosclerosis. 173:171-183. DOI.
  • Chan C; Lechler RI; George AJ. (Mar 2004). Tolerance mechanisms and recent progress. Transplant Proc. 36:561S-569S. DOI.
  • Arancibia-Cárcamo CV; Osawa H; Arnett HA; Háskova Z; George AJ; Ono SJ; Ting JP; Streilein JW. (Feb 2004). A CIITA-independent pathway that promotes expression of endogenous rather than exogenous peptides in immune-privileged sites. Eur J Immunol. 34:471-480. DOI.
  • Manunta M; Tan PH; Sagoo P; Kashefi K; George AJ. (2004). Gene delivery by dendrimers operates via a cholesterol dependent pathway. Nucleic Acids Res. 32:2730-2739. DOI.
  • Ardjomand N; McAlister JC; Rogers NJ; Tan PH; George AJ; Larkin DF. (Sep 2003). Modulation of costimulation by CD28 and CD154 alters the kinetics and cellular characteristics of corneal allograft rejection. Invest Ophthalmol Vis Sci. 44:3899-3905.
  • Chan C; George AJT; Stark J. (1 Aug 2003). T cell sensitivity and specificity - Kinetic proofreading revisited. DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B. 3:343-360. Author weblink.
  • George AJ; Lee L; Pitzalis C. (May 2003). Isolating ligands specific for human vasculature using in vivo phage selection. Trends Biotechnol. 21:199-203.
  • Tan PH; Manunta M; Ardjomand N; Xue SA; Larkin DF; Haskard DO; Taylor KM; George AJ. (Apr 2003). Antibody targeted gene transfer to endothelium. J Gene Med. 5:311-323. DOI.
  • Hudde T; Comer RM; Kinsella MT; Buttery L; Luthert PJ; Polak JM; George AJ; Larkin DF. (Sep 2002). Modulation of hydrogen peroxide induced injury to corneal endothelium by virus mediated catalase gene transfer. Br J Ophthalmol. 86:1058-1062.
  • Lee L; Buckley C; Blades MC; Panayi G; George AJ; Pitzalis C. (Aug 2002). Identification of synovium-specific homing peptides by in vivo phage display selection. Arthritis Rheum. 46:2109-2120. DOI.
  • George AJ. (Jul 2002). Is the number of genes we possess limited by the presence of an adaptive immune system?. Trends Immunol. 23:351-355.
  • Dougan T; Levy JB; Salama A; George AJ; Pusey CD. (Jun 2002). Characterization of autoantibodies from patients with Goodpasture's disease using a resonant mirror biosensor. Clin Exp Immunol. 128:555-561.
  • Salama AD; Dougan T; Levy JB; Cook HT; Morgan SH; Naudeer S; Maidment G; George AJ; et alEvans D; Lightstone L; Pusey CD. (Jun 2002). Goodpasture's disease in the absence of circulating anti-glomerular basement membrane antibodies as detected by standard techniques. Am J Kidney Dis. 39:1162-1167. DOI.
  • Comer RM; King WJ; Ardjomand N; Theoharis S; George AJ; Larkin DF. (Apr 2002). Effect of administration of CTLA4-Ig as protein or cDNA on corneal allograft survival. Invest Ophthalmol Vis Sci. 43:1095-1103.
  • George AJ; Gale R; Winston R; Korn D. (Feb 2002). Research governance at the crossroads. Nat Med. 8:99-101. DOI.
  • Yates A; Chan CC; Callard RE; George AJ; Stark J. (Sep 2001). An approach to modelling in immunology. Brief Bioinform. 2:245-257.
  • Rayner SA; Larkin DF; George AJ. (Jun 2001). TNF receptor secretion after ex vivo adenoviral gene transfer to cornea and effect on in vivo graft survival. Invest Ophthalmol Vis Sci. 42:1568-1573.
  • Chan C; George AJ; Stark J. (8 May 2001). Cooperative enhancement of specificity in a lattice of T cell receptors. Proc Natl Acad Sci U S A. 98:5758-5763. DOI.
  • George AJ. (May 2001). Measurement of the kinetics of biomolecular interactions using the IAsys resonant mirror biosensor. Curr Protoc Immunol. Chapter 18:Unit-18.5. DOI.
  • Tan PH; King WJ; Chen D; Awad HM; Mackett M; Lechler RI; Larkin DF; George AJ. (27 Feb 2001). Transferrin receptor-mediated gene transfer to the corneal endothelium. Transplantation. 71:552-560.
  • Griffith ME; Coulthart A; Pemberton S; George AJ; Pusey CD. (Jan 2001). Anti-neutrophil cytoplasmic antibodies (ANCA) from patients with systemic vasculitis recognize restricted epitopes of proteinase 3 involving the catalytic site. Clin Exp Immunol. 123:170-177.
  • George AJT; Larkin F. (2001). Corneal transplantation: prospects for gene therapy. Eye News. 6, 7:36-48.
  • Huston JS; George AJ. (2001). Engineered antibodies take center stage. Hum Antibodies. 10:127-142.
  • King WJ; Comer RM; Hudde T; Larkin DF; George AJ. (27 Oct 2000). Cytokine and chemokine expression kinetics after corneal transplantation. Transplantation. 70:1225-1233.
  • George AJ; Arancibia-Cárcamo CV; Awad HM; Comer RM; Fehevari Z; King WJ; Kadifachi M; Hudde T; et alKerouedan-Lebossé C; Mirza F; Barbaros Oral H; Rayner SA; Tan PH; Tay E; Larkin DF. (Oct 2000). Gene delivery to the corneal endothelium. Am J Respir Crit Care Med. 162:S194-S200.
  • Rayner SA; King WJ; Comer RM; Isaacs JD; Hale G; George AJ; Larkin DF. (Oct 2000). Local bioactive tumour necrosis factor (TNF) in corneal allotransplantation. Clin Exp Immunol. 122:109-116.
  • Johns M; George AJ; Ritter MA. (26 May 2000). In vivo selection of sFv from phage display libraries. J Immunol Methods. 239:137-151.
  • Hudde T; Rayner SA; De Alwis M; Thrasher AJ; Smith J; Coffin RS; George AJ; Larkin DF. (May 2000). Adeno-associated and herpes simplex viruses as vectors for gene transfer to the corneal endothelium. Cornea. 19:369-373.
  • George AJ. (27 Mar 2000). Peptide-mediated non-viral gene transfer for transplantation. Transplantation. 69:1031-1033.
  • George AJ; Gray I. (Jan 2000). Jumping or walking: which is better?. Immunol Today. 21:55.
  • Oral HB; George AJT; Haskard DO. (2000). Prevention of hydrogen peroxide- and cisplatin- induced apoptosis by intracellular catalase expression. Turkish Journal of Biology. 24:685-696.
  • Midulla M; Verma R; Pignatelli M; Ritter MA; Courtenay-Luck NS; George AJ. (1 Jan 2000). Source of oncofetal ED-B-containing fibronectin: implications of production by both tumor and endothelial cells. Cancer Res. 60:164-169.
  • George AJT. (10 Dec 1999). Antibody engineering: an introduction. JOURNAL OF IMMUNOLOGICAL METHODS. 231:1-1. Author weblink.
  • Sepp A; Farrar CA; Dorling T; Cairns T; George AJ; Lechler RI. (10 Dec 1999). Inhibition of expression of the Galalpha1-3Gal epitope on porcine cells using an intracellular single-chain antibody directed against alpha1,3galactosyltransferase. J Immunol Methods. 231:191-205.
  • Chan CC; Stark J; George AJ. (7 Nov 1999). Analysis of cytokine dynamics in corneal allograft rejection. Proc Biol Sci. 266:2217-2223. DOI.
  • Callard R; George AJ; Stark J. (Nov 1999). Cytokines, chaos, and complexity. Immunity. 11:507-513.
  • Hudde T; Rayner SA; Comer RM; Weber M; Isaacs JD; Waldmann H; Larkin DF; George AJ. (May 1999). Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium. Gene Ther. 6:939-943. DOI.
  • George AJT; Gray D. (1 Apr 1999). Receptor editing during affinity maturation. IMMUNOLOGY TODAY. 20:196-196. Author weblink DOI.
  • Nicholson S; Gallop JL; Law P; Thomas H; George AJT. (6 Mar 1999). Monitoring antibody responses to cancer vaccination with a resonant mirror biosensor. LANCET. 353:808-808. Author weblink DOI.
  • Oral HB; Arancibia-Cárcamo CV; Haskard DO; George AJ. (1 Feb 1999). A method for determining the cytoprotective effect of catalase in transiently transfected cell lines and in corneal tissue. Anal Biochem. 267:196-202. DOI.
  • Palmer DB; Crompton T; Marandi MB; George AJ; Ritter MA. (Feb 1999). Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development. Immunology. 96:236-245.
  • Lord GM; Lechler RI; George AJ. (Jan 1999). A kinetic differentiation model for the action of altered TCR ligands. Immunol Today. 20:33-39.
  • Riesbeck K; Chen D; Kemball-Cook G; McVey JH; George AJ; Tuddenham EG; Dorling A; Lechler RI. (15 Dec 1998). Expression of hirudin fusion proteins in mammalian cells: a strategy for prevention of intravascular thrombosis. Circulation. 98:2744-2752.
  • McKay PF; Imami N; Johns M; Taylor-Fishwick DA; Sedibane LM; Totty NF; Hsuan JJ; Palmer DB; et alGeorge AJ; Foxwell BM; Ritter MA. (Dec 1998). The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family. Eur J Immunol. 28:4071-4083. DOI.
  • Lee J; Cairns T; McKane W; Rashid M; George AJ; Taube D. (27 Oct 1998). Demonstration of IgM antibodies of high affinity within the anti-Galalpha1-3Gal antibody repertoire. Transplantation. 66:1117-1119.
  • Heelan BT; Osman S; Blyth A; Schnorr L; Jones T; George AJ. (27 Oct 1998). Use of 2-[18F]fluoro-2-deoxyglucose as a potential agent in the prediction of graft rejection by positron emission tomography. Transplantation. 66:1101-1103.
  • Hussain R; Siligardi G; George AJT; Verma R. (1 Aug 1998). Immobilised and non-immobilised ligand interaction studies of monoclonal antibody BC-1 and ED-B containing fibronectin fragment. PROTEIN AND PEPTIDE LETTERS. 5:215-219.
  • Verma R; Boleti E; George AJ. (1 Jul 1998). Antibody engineering: comparison of bacterial, yeast, insect and mammalian expression systems. J Immunol Methods. 216:165-181.
  • Mahiouz DL; Aichinger G; Haskard DO; George AJ. (15 Mar 1998). Expression of recombinant anti-E-selectin single-chain Fv antibody fragments in stably transfected insect cell lines. J Immunol Methods. 212:149-160.
  • Hart SL; Arancibia-Carcamo CV; Wolfert MA; Mailhos C; O'Reilly NJ; Ali RR; Coutelle C; George AJT; et alHarbottle RP; Knight AM; Larkin DFP; Levinsky RJ; Seymour LW; Thrasher AJ; Kinnon C. (1 Mar 1998). Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector. HUMAN GENE THERAPY. 9:575-585. Author weblink DOI.
  • Patel MJ; Webb EJ; Shelbourn TE; Mattia-Goldberg C; George AJT; Zhang F; Moore EG; Nelson DJ. (15 Jan 1998). Absence of immunogenicity of diaspirin cross-linked hemoglobin in humans. BLOOD. 91:710-716. Author weblink.
  • Arancibia-Cárcamo CV; Oral HB; Haskard DO; Larkin DF; George AJ. (15 Jan 1998). Lipoadenofection-mediated gene delivery to the corneal endothelium: prospects for modulating graft rejection. Transplantation. 65:62-67.
  • Oral HB; George AJ; Haskard DO. (1998). A sensitive fluorometric assay for determining hydrogen peroxide-mediated sublethal and lethal endothelial cell injury. Endothelium. 6:143-151.
  • Rayner SA; Gallop JL; George AJ; Larkin DF. (1998). Distribution of integrins alpha v beta 5, alpha v beta 3 and alpha v in normal human cornea: possible implications in clinical and therapeutic adenoviral infection. Eye (Lond). 12 ( Pt 2):273-277. DOI.
  • Harrison AA; Stocker CJ; Chapman PT; Tsang YT; Huehns TY; Gundel RH; Peters AM; Davies KA; et alGeorge AJ; Robinson MK; Haskard DO. (1 Nov 1997). Expression of vascular cell adhesion molecule-1 by vascular endothelial cells in immune and nonimmune inflammatory reactions in the skin. J Immunol. 159:4546-4554.
  • George AJT; Gallop JL; Rashid M. (1 Sep 1997). Kinetics of biomolecular interactions. EXPERT OPINION ON THERAPEUTIC PATENTS. 7:947-963. DOI.
  • Oral HB; Larkin DF; Fehervari Z; Byrnes AP; Rankin AM; Haskard DO; Wood MJ; Dallman MJ; et alGeorge AJ. (Jul 1997). Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea. Gene Ther. 4:639-647. DOI.
  • Fehervari Z; Rayner SA; Oral HB; George AJ; Larkin DF. (Jul 1997). Gene transfer to ex vivo stored corneas. Cornea. 16:459-464.
  • Palmer DB; George AJ; Ritter MA. (Jul 1997). Selection of antibodies to cell surface determinants on mouse thymic epithelial cells using a phage display library. Immunology. 91:473-478.
  • Turner DJ; Ritter MA; George AJ. (23 Jun 1997). Importance of the linker in expression of single-chain Fv antibody fragments: optimisation of peptide sequence using phage display technology. J Immunol Methods. 205:43-54.
  • Deonarain MP; Rowlinson-Busza G; George AJ; Epenetos AA. (Jan 1997). Redesigned anti-human placental alkaline phosphatase single-chain Fv: soluble expression, characterization and in vivo tumour targeting. Protein Eng. 10:89-98.
  • George AJT; Ritter MA; Urch CE. (1 Jun 1996). Research training and Calman reforms: A role for the MSc?. POSTGRADUATE MEDICAL JOURNAL. 72:321-322. Author weblink.
  • George AJT; Epenetos AA. (1 May 1996). Advances in antibody engineering. EXPERT OPINION ON THERAPEUTIC PATENTS. 6:441-456. Author weblink.
  • George A; Huston JS; Haber E. (1 May 1996). Exploring and exploiting the antibody and Ig superfamily combining sites. NATURE BIOTECHNOLOGY. 14:584-584. Author weblink DOI.
  • Heelan BT; Thompson M; McCormack A; Peters AM; Batchelor JR; George AJT. (27 Apr 1996). The kinetics of MHC class I and class II expression in rat renal allografts - In vivo localization with radiolabeled antibodies. TRANSPLANTATION. 61:1274-1277. Author weblink DOI.
  • Larkin DFP; Oral HB; Ring CJA; Lemoine NR; George AJT. (15 Feb 1996). Adenovirus-mediated gene delivery to the corneal endothelium. TRANSPLANTATION. 61:363-370. Author weblink DOI.
  • Hornick P; George A. (Jan 1996). Blood contact activation: pathophysiological effects and therapeutic approaches. Perfusion. 11:3-19.
  • GEORGE AJT; JAMAR F; TAI MS; HEELAN BT; ADAMS GP; MCCARTNEY JE; HOUSTON LL; WEINER LM; et alOPPERMANN H; PETERS AM; HUSTON JS. (29 Aug 1995). RADIOMETAL LABELING OF RECOMBINANT PROTEINS BY A GENETICALLY-ENGINEERED MINIMAL CHELATION SITE - TC-99M COORDINATION BY SINGLE-CHAIN FV ANTIBODY FUSION PROTEINS THROUGH A C-TERMINAL CYSTEINYL PEPTIDE. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 92:8358-8362. Author weblink DOI.
  • GEORGE AJT; FRENCH RR; GLENNIE MJ. (14 Jun 1995). MEASUREMENT OF KINETIC BINDING CONSTANTS OF A PANEL OF ANTI-SAPORIN ANTIBODIES USING A RESONANT MIRROR BIOSENSOR. JOURNAL OF IMMUNOLOGICAL METHODS. 183:51-63. Author weblink DOI.
  • FRENCH RR; PENNEY CA; BROWNING AC; STIRPE F; GEORGE AJT; GLENNIE MJ. (1 May 1995). DELIVERY OF THE RIBOSOME-INACTIVATING PROTEIN, GELONIN, TO LYMPHOMA-CELLS VIA CD22 AND CD38 USING BISPECIFIC ANTIBODIES. BRITISH JOURNAL OF CANCER. 71:986-994. Author weblink DOI.
  • GEORGE AJT; RITTER MA; LECHLER RI. (1 May 1995). DISEASE SUSCEPTIBILITY, TRANSPLANTATION AND THE MHC. IMMUNOLOGY TODAY. 16:209-211. DOI.
  • BARBONI E; RIVERO BP; GEORGE AJT; MARTIN S; RENOUF DV; HOUNSELL EF; BARBER PC; MORRIS RJ. (1 Feb 1995). THE GLYCOPHOSPHATIDYLINOSITOL ANCHOR AFFECTS THE CONFORMATION OF THY-1 PROTEIN. JOURNAL OF CELL SCIENCE. 108:487-497. Author weblink.
  • Jost CR; Kurucz I; Jacobus CM; Titus JA; George AJ; Segal DM. (21 Oct 1994). Mammalian expression and secretion of functional single-chain Fv molecules. J Biol Chem. 269:26267-26273.
  • GEORGE AJT; TITUS JA; JOST CR; KURUCZ I; PEREZ P; ANDREW SM; NICHOLLS PJ; HUSTON JS; et alSEGAL DM. (15 Feb 1994). REDIRECTION OF T-CELL-MEDIATED CYTOTOXICITY BY A RECOMBINANT SINGLE-CHAIN FV MOLECULE. JOURNAL OF IMMUNOLOGY. 152:1802-1811. Author weblink.
  • GEORGE AJT. (1 Feb 1994). SURFACE-BOUND CYTOKINES - A POSSIBLE EFFECTOR MECHANISM IN BACTERIAL IMMUNITY. IMMUNOLOGY TODAY. 15:88-89. Author weblink DOI.
  • GEORGE AJT. (1 Jan 1994). ANTIBODY ENGINEERING. ENDEAVOUR. 18:27-31. Author weblink DOI.
  • Kurucz I; Jost CR; George AJ; Andrew SM; Segal DM. (1 May 1993). A bacterially expressed single-chain Fv construct from the 2B4 T-cell receptor. Proc Natl Acad Sci U S A. 90:3830-3834.
  • Segal DM; Qian JH; Mezzanzanica D; Garrido MA; Titus JA; Andrew SM; George AJ; Jost CR; et alPerez P; Wunderlich JR. (Aug 1992). Targeting of anti-tumor responses with bispecific antibodies. Immunobiology. 185:390-402.
  • Segal DM; Qian JH; Titus JA; Moreno MB; George AJ; Jost CR; Kurucz I; el-Gamil M; et alWunderlich JR. (1992). Targeted cytokine production. Int J Cancer Suppl. 7:36-38.
  • GREENMAN J; TUTT AL; GEORGE AJT; PULFORD KAF; STEVENSON GT; GLENNIE MJ. (1 Nov 1991). CHARACTERIZATION OF A NEW MONOCLONAL ANTI-FC-GAMMA-RII ANTIBODY, AT10, AND ITS INCORPORATION INTO A BISPECIFIC F(AB')2 DERIVATIVE FOR RECRUITMENT OF CYTOTOXIC EFFECTORS. MOLECULAR IMMUNOLOGY. 28:1243-1254. Author weblink DOI.
  • GEORGE AJT; FOREMAN RC; STEVENSON FK. (1 Jul 1991). CHARACTERIZATION OF A LIGHT CHAIN LOSS VARIANT OF THE BCL1 LYMPHOMA. MOLECULAR IMMUNOLOGY. 28:789-799. Author weblink DOI.
  • Urch CE; George AJ; Stevenson GT; Bolognesi A; Stirpe F; Weller R; Glennie MJ. (1 Apr 1991). Intra-thecal treatment of leptomeningeal lymphoma with immunotoxin. Int J Cancer. 47:909-915.
  • George AJ; McBride HM; Glennie MJ; Smith LJ; Stevenson FK. (Apr 1991). Monoclonal antibodies raised against the idiotype of the murine B cell lymphoma, BCL1 act primarily with heavy chain determinants. Hybridoma. 10:219-227.
  • DYKE RJ; MCBRIDE H; GEORGE AJT; HAMBLIN TJ; STEVENSON FK. (1 Jan 1991). IDIOTYPIC VACCINATION AGAINST B-CELL LYMPHOMA LEADS TO DORMANT TUMOR. CELLULAR IMMUNOLOGY. 132:70-83. Author weblink DOI.
  • GEORGE AJT. (1 Jan 1991). REGULATION OF THE B-CELL RESPONSE BY CYTOKINES. TRANSFUSION SCIENCE. 12:43-57. Author weblink DOI.
  • WILSON A; GEORGE AJT; KING CA; STEVENSON FK. (1 Dec 1990). RECOGNITION OF A B-CELL LYMPHOMA BY ANTIIDIOTYPIC T-CELLS. JOURNAL OF IMMUNOLOGY. 145:3937-3943. Author weblink.
  • GEORGE AJT; STEVENSON FK. (1 Oct 1990). HUMORAL EFFECTOR MECHANISMS IN THE IMMUNITY TO CANCER. IMMUNOLOGY TODAY. 11:348-349. Author weblink DOI.
  • Stevenson FK; George AJ; Glennie MJ. (1990). Anti-idiotypic therapy of leukemias and lymphomas. Chem Immunol. 48:126-166.
  • George AJ; Stevenson FK. (1989). Prospects for the treatment of B cell tumors using idiotypic vaccination. Int Rev Immunol. 4:271-310.
  • GEORGE AJT; FOLKARD SG; HAMBLIN TJ; STEVENSON FK. (15 Sep 1988). IDIOTYPIC VACCINATION AS A TREATMENT FOR A B-CELL LYMPHOMA. JOURNAL OF IMMUNOLOGY. 141:2168-2174. Author weblink.
  • GEORGE AJT; SPELLERBERG MB; STEVENSON FK. (1 Mar 1988). IDIOTYPE VACCINATION LEADS TO THE EMERGENCE OF A STABLE SURFACE IG-NEGATIVE VARIANT OF THE MOUSE LYMPHOMA BCL1, WITH DIFFERENT GROWTH-CHARACTERISTICS. JOURNAL OF IMMUNOLOGY. 140:1695-1701. Author weblink.
  • GEORGE AJT; TUTT AL; STEVENSON FK. (15 Jan 1987). ANTIIDIOTYPIC MECHANISMS INVOLVED IN SUPPRESSION OF A MOUSE B-CELL LYMPHOMA, BCL1. JOURNAL OF IMMUNOLOGY. 138:628-634. Author weblink.
  • Stevenson FK; George AJ; Tutt AL; Glennie MJ; Stevenson GT. (1987). Involvement of innate and induced anti-idiotypic mechanisms in suppression of B cell tumors. Monogr Allergy. 22:184-193.
  • STEVENSON FK; GEORGE AJT; WALTERS MT; HAMBLIN TJ. (1 Jan 1986). ANALYSIS OF SOLUBLE HLA CLASS-II ANTIGENIC MATERIAL IN PATIENTS WITH IMMUNOLOGICAL DISEASES USING MONOCLONAL-ANTIBODIES. JOURNAL OF IMMUNOLOGICAL METHODS. 86:187-190. Author weblink DOI.

Books

  • George AJT; Urch CE. Diagnostic and Therapeutic Antibodies. 1-477. Humana Press, Totowa, New Jersey (2000).

Chapters in books

  • Lechler, RI; George, AJT. Transplantation and Rejection. In Immunology. 7th:383-399. Male D (ed); Brostoff J (ed); Roth DB (ed); Roitt I (ed). Mosby Elsevier, Philadelphia (2006).
  • George AJT. Monoclonal antibody therapy. In Topley & Wilson's Microbiology and Microbial Infections: Immunology. 10th Edition. 353-374. SHE K (ed); Steward MW (ed). Hodder Arnold, London (2005).
  • George, AJT; Lechler RI. Xenotransplantation: will pigs fly?. In Future Strategies for Tissue and Organ Replacement. 215-236. (2002).
  • George AJT. The antibody molecule. In Diagnostic and Therapeutic Antibodies. 1-21. AJT G (ed); Urch CE (ed). Humana Press, Totowa, NJ (2000).
  • George AJT. Use of biosensors to measure the kinetics of antibody-antigen interactions. In Diagnostic and Therapeutic Antibodies. 363-372. AJT G (ed); Urch CE (ed). Humana Press, Totowa NJ (2000).

Conferences

  • Buckland M; Jago C; Fazekesova H; George A; Lechler R; Lombardi G. Aspirin modified dendritic cells are potent inducers of allo-specific regulatory T-cells. 7th International Conference on New Trends in Immunosuppression and Immunotherapy. 6:1895-1901. (20 Dec 2006).
  • Boleti E; George AJT; Epenetos AA. Therapeutic monoclonals. 655th Meeting of the Biochemical-Society. 23:1044-1047. (Nov 1995).
  • GEORGE AJT; TITUS JA; JOST CR; KURUCZ I; PEREZ P; ANDREW SM; NICHOLLS PJ; HUSTON JS; et alSEGAL DM. REDIRECTION OF CELLULAR CYTOTOXICITY - A 2-STEP APPROACH USING RECOMBINANT SINGLE-CHAIN FV MOLECULES. 11th Conference on Advances in the Applications of Monoclonal Antibodies in Clinical Oncology, 23 May 1994 - 26 May 1994. 26:153-165. HUMANA PRESS INC (1 Jun 1995). Author weblink.
  • SEGAL DM; QIAN JH; MEZZANZANICA D; GARRIDO MA; TITUS JA; ANDREW SM; GEORGE AJT; JOST CR; et alPEREZ P; WUNDERLICH JR. TARGETING OF ANTITUMOR RESPONSES WITH BISPECIFIC ANTIBODIES. 7TH SYMP ON SIGNALS AND SIGNAL PROCESSING IN THE IMMUNE SYSTEM. 185:390-402. (Aug 1992).
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