Professor Ajit Lalvani

Publications


Journals

  • Lalvani A; Behr MA; Sridhar S. (3 Feb 2012). Innate Immunity to TB: A Druggable Balancing Act. Cell. 148:389-391. DOI.
  • Dosanjh DP; Bakir M; Millington KA; Soysal A; Aslan Y; Efee S; Deeks JJ; Lalvani A. (2011). Novel M tuberculosis antigen-specific T-cells are early markers of infection and disease progression. PLoS One. 6:e28754. DOI.
  • Singanayagam A; Sridhar S; Dhariwal J; Abdel-Aziz D; Munro K; Connell DW; George PM; Molyneaux PL; et alCooke GS; Burroughs AK; Lalvani A; Wickremasinghe M; Kon OM. (26 Jan 2012). A Comparison between Two Strategies for Monitoring Hepatic Function during Anti-Tuberculous Therapy. Am J Respir Crit Care Med. DOI.
  • Kasprowicz VO; Churchyard G; Lawn SD; Squire SB; Lalvani A. (15 Nov 2011). Diagnosing latent tuberculosis in high-risk individuals: rising to the challenge in high-burden areas. J Infect Dis. 204 Suppl 4:S1168-S1178. DOI.
  • Sridhar S; Pollock K; Lalvani A. (Sep 2011). Redefining latent tuberculosis. Future Microbiol. 6:1021-1035. DOI.
  • Kasprowicz VO; Mitchell JE; Chetty S; Govender P; Huang KH; Fletcher HA; Webster DP; Brown S; et alKasmar A; Millington K; Day CL; Mkhwanazi N; McClurg C; Chonco F; Lalvani A; Walker BD; Ndung'u T; Klenerman P. (2011). A molecular assay for sensitive detection of pathogen-specific T-cells. PLoS One. 6:e20606. DOI.
  • Navani N; Molyneaux PL; Breen RA; Connell DW; Jepson A; Nankivell M; Brown JM; Morris-Jones S; et alNg B; Wickremasinghe M; Lalvani A; Rintoul RC; Santis G; Kon OM; Janes SM. (Oct 2011). Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study. Thorax. 66:889-893. DOI.
  • Pollock KM; Lalvani A. (2008). Tuberculosis of the central nervous system: recognition, diagnosis and treatment in a low-prevalence country. Acute Med. 7:113-121.
  • Broniatowska B; Allmendinger A; Kaiser M; Montamat-Sicotte D; Hingley-Wilson S; Lalvani A; Guiry M; Blunden G; et alTasdemir D. (May 2011). Antiprotozoal, antitubercular and cytotoxic potential of cyanobacterial (blue-green algal) extracts from Ireland. Nat Prod Commun. 6:689-694.
  • Montamat-Sicotte DJ; Millington KA; Willcox CR; Hingley-Wilson S; Hackforth S; Innes J; Kon OM; Lammas DA; et alMinnikin DE; Besra GS; Willcox BE; Lalvani A. (Jun 2011). A mycolic acid-specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection. J Clin Invest. 121:2493-2503. DOI.
  • Pareek M; Watson JP; Ormerod LP; Kon OM; Woltmann G; White PJ; Abubakar I; Lalvani A. (Jun 2011). Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis. Lancet Infect Dis. 11:435-444. DOI.
  • Süzgeç-Selçuk S; Meriçli AH; Güven KC; Kaiser M; Casey R; Hingley-Wilson S; Lalvani A; Tasdemir D. (May 2011). Evaluation of Turkish seaweeds for antiprotozoal, antimycobacterial and cytotoxic activities. Phytother Res. 25:778-783. DOI.
  • Pollock K; Tam H; Montamat-Sicotte D; Grass L; Cooke G; Kapembwa M; Taylor G; Lalvani A. (Apr 2011). Screening for latent tuberculosis infection in HIV: should we do more?. HIV MED. 12:42-42.
  • Millington KA; Fortune SM; Low J; Garces A; Hingley-Wilson SM; Wickremasinghe M; Kon OM; Lalvani A. (5 Apr 2011). Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A. 108:5730-5735. DOI.
  • Sester U; Fousse M; Dirks J; Mack U; Prasse A; Singh M; Lalvani A; Sester M. (2011). Whole-blood flow-cytometric analysis of antigen-specific CD4 T-cell cytokine profiles distinguishes active tuberculosis from non-active states. PLoS One. 6:e17813. DOI.
  • Pareek M; Abubakar I; White PJ; Garnett GP; Lalvani A. (Nov 2011). U.K. immigrant screening is inversely related to regional tuberculosis burden. Thorax. 66:1010. DOI.
  • Westwood IM; Bhakta S; Russell AJ; Fullam E; Anderton MC; Kawamura A; Mulvaney AW; Vickers RJ; et alBhowruth V; Besra GS; Lalvani A; Davies SG; Sim E. (Jan 2010). Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars. Protein Cell. 1:82-95. DOI.
  • Casey R; Blumenkrantz D; Millington K; Montamat-Sicotte D; Kon OM; Wickremasinghe M; Bremang S; Magtoto M; et alSridhar S; Connell D; Lalvani A. (2010). Enumeration of functional T-cell subsets by fluorescence-immunospot defines signatures of pathogen burden in tuberculosis. PLoS One. 5:e15619. DOI.
  • Pareek M; Abubakar I; White PJ; Garnett GP; Lalvani A. (May 2011). Tuberculosis screening of migrants to low-burden nations: insights from evaluation of UK practice. Eur Respir J. 37:1175-1182. DOI.
  • Lalvani A; Sridhar S. (Dec 2010). BCG vaccination: 90 years on and still so much to learn ... Thorax. 65:1036-1038. DOI.
  • Millington KA; Gooding S; Hinks TS; Reynolds DJ; Lalvani A. (1 Dec 2010). Mycobacterium tuberculosis-specific cellular immune profiles suggest bacillary persistence decades after spontaneous cure in untreated tuberculosis. J Infect Dis. 202:1685-1689. DOI.
  • Spavieri J; Allmendinger A; Kaiser M; Casey R; Hingley-Wilson S; Lalvani A; Guiry MD; Blunden G; et alTasdemir D. (Nov 2010). Antimycobacterial, antiprotozoal and cytotoxic potential of twenty-one brown algae (Phaeophyceae) from British and Irish waters. Phytother Res. 24:1724-1729. DOI.
  • Joshi MS; Lalvani A. (Aug 2010). 'Home from home': risk perceptions, malaria and the use of chemoprophylaxis among UK South Asians. Ethn Health. 15:365-375. DOI.
  • Mutsvangwa J; Millington KA; Chaka K; Mavhudzi T; Cheung YB; Mason PR; Butterworth AE; Corbett EL; et alLalvani A. (Apr 2010). Identifying recent Mycobacterium tuberculosis transmission in the setting of high HIV and TB burden. Thorax. 65:315-320. DOI.
  • Dodd PJ; Millington KA; Ghani AC; Mutsvangwa J; Butterworth AE; Lalvani A; Corbett EL. (1 May 2010). Interpreting tuberculin skin tests in a population with a high prevalence of HIV, tuberculosis, and nonspecific tuberculin sensitivity. Am J Epidemiol. 171:1037-1045. DOI.
  • Pareek M; White PJ; Lalvani A; Garnett GP. (Dec 2009). MODELLING THE HEALTH IMPACT AND COST-EFFECTIVENESS OF SCREENING NEW ENTRANTS TO THE UK FOR LATENT TUBERCULOSIS INFECTION. J INFECTION. 59:S442-S442.
  • Allmendinger A; Spavieri J; Kaiser M; Casey R; Hingley-Wilson S; Lalvani A; Guiry M; Blunden G; et alTasdemir D. (Jul 2010). Antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three British and Irish red algae. Phytother Res. 24:1099-1103. DOI.
  • Spavieri J; Kaiser M; Casey R; Hingley-Wilson S; Lalvani A; Blunden G; Tasdemir D. (Jul 2010). Antiprotozoal, antimycobacterial and cytotoxic potential of some british green algae. Phytother Res. 24:1095-1098. DOI.
  • Lalvani A; Pareek M. (2010). A 100 year update on diagnosis of tuberculosis infection. Br Med Bull. 93:69-84. DOI.
  • Lalvani A; Pareek M. (Apr 2010). Interferon gamma release assays: principles and practice. Enferm Infecc Microbiol Clin. 28:245-252. DOI.
  • Hinks TS; Dosanjh DP; Innes JA; Pasvol G; Hackforth S; Varia H; Millington KA; Liu XQ; et alBakir M; Soysal A; Davidson RN; Gunatheesan R; Lalvani A. (Dec 2009). Frequencies of region of difference 1 antigen-specific but not purified protein derivative-specific gamma interferon-secreting T cells correlate with the presence of tuberculosis disease but do not distinguish recent from remote latent infections. Infect Immun. 77:5486-5495. DOI.
  • Lalvani A; Hingley-Wilson S. (Jul 2009). Editorial: Live or let die--does HIV exacerbate tuberculosis by attenuating M. tuberculosis-induced apoptosis?. J Leukoc Biol. 86:9-11. DOI.
  • Lalvani A; Millington KA. (17 Mar 2009). The Predictive Value of the ELISpot-Based Interferon-gamma-Release Assay for Tuberculosis Disease Response. ANN INTERN MED. 150:429-430.
  • Bakir M; Dosanjh DP; Deeks JJ; Soysal A; Millington KA; Efe S; Aslan Y; Polat D; et alKodalli N; Yagci A; Barlan I; Bahceciler N; Demiralp EE; Lalvani A. (1 Feb 2009). Use of T cell-based diagnosis of tuberculosis infection to optimize interpretation of tuberculin skin testing for child tuberculosis contacts. Clin Infect Dis. 48:302-312. DOI.
  • Bakir M; Millington KA; Soysal A; Deeks JJ; Efee S; Aslan Y; Dosanjh DPS; Lalvani A. (2 Dec 2008). Prognostic Value of a T-Cell-Based, Interferon-gamma Biomarker in Children with Tuberculosis Contact. ANN INTERN MED. 149:777-W163.
  • Lalvani A; Millington KA. (Dec 2008). T-cell interferon-gamma release assays: can we do better?. EUR RESPIR J. 32:1428-1430. DOI.
  • Hingley-Wilson S; Lalvani A. (Dec 2008). An exit strategy for the tubercle bacillus?. NAT REV MICROBIOL. 6:954-954. DOI.
  • Bakir M; Millington KA; Soysal A; Deeks JJ; Efee S; Aslan Y; Dosanjh DP; Lalvani A. (2 Dec 2008). Prognostic value of a T-cell-based, interferon-gamma biomarker in children with tuberculosis contact. Ann Intern Med. 149:777-787.
  • Lalvani A; Millington KA. (Dec 2008). Screening for tuberculosis infection prior to initiation of anti-TNF therapy. Autoimmun Rev. 8:147-152. DOI.
  • Lee B; Lim A; Lalvani A; Descamps MJ; Leonard R; Nallamala S; Lewis JS; Coombes RC; et alStebbing J. (Dec 2008). The clinical significance of radiologically detected silent pulmonary nodules in early breast cancer. Ann Oncol. 19:2001-2006. DOI.
  • Thomas MM; Hinks TSC; Raghuraman S; Ramalingam N; Ernst M; Nau R; Lange C; Kosters K; et alGnanamuthu C; John GT; Marshall B; Lalvani A. (Jun 2008). Rapid diagnosis of Mycobacterium tuberculosis meningitis by enumeration of cerebrospinal fluid antigen-specific T-cells. INT J TUBERC LUNG D. 12:651-657.
  • Lalvani A; Meroni PL; Millington KA; Modolo ML; Plebani M; Tincani A; Villalta D; Doria A; et alGhirardello A. (Jan 2008). Recent advances in diagnostic technology: applications in autoimmune and infectious diseases. CLIN EXP RHEUMATOL. 26:S62-S66.
  • Dosanjh D; Hinks T; Innes J; Deeks J; Pasvol G; Hackforth S; Varia H; Liu XQ; et alMillington K; Gunatheesan R; Guyot-Revol V; Lalvani A. (Apr 2008). Improved diagnostic evaluation of suspected tuberculosis by use of T cell-based assay in routine practice. J INFECTION. 56:302-302.
  • Dosanjh DPS; Hinks TSC; Innes JA; Deeks JJ; Pasvol G; Hackforth S; Varia H; Millington KA; et alGunatheesan R; Guyot-Revol V; Lalvani A. (4 Mar 2008). Improved diagnostic evaluation of suspected tuberculosis. ANN INTERN MED. 148:325-W72.
  • Lalvani A; Millington KA. (1 Apr 2008). T cells and tuberculosis: Beyond interferon-gamma. J INFECT DIS. 197:941-943. DOI.
  • Kösters K; Nau R; Bossink A; Greiffendorf I; Jentsch M; Ernst M; Thijsen S; Hinks T; et alLalvani A; Lange C. (Dec 2008). Rapid diagnosis of CNS tuberculosis by a T-cell interferon-gamma release assay on cerebrospinal fluid mononuclear cells. Infection. 36:597-600. DOI.
  • Seyler L; Lalvani A; Collins L; Goddard L; Bowler ICJW. (Oct 2007). Safety and cost savings of an improved three-day rule for stool culture in hospitalised children and adults. J HOSP INFECT. 67:121-126. DOI.
  • Lange C; Jafari C; Lalvani A. (1 Aug 2007). Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked immunospot. AM J RESP CRIT CARE. 176:317-317.
  • Lalvani A. (Jun 2007). Diagnosing tuberculosis infection in the 21st century: new tools to tackle an old enemy. Chest. 131:1898-1906. DOI.
  • Lalvani A; Millington KA. (Jun 2007). T cell-based diagnosis of childhood tuberculosis infection. Curr Opin Infect Dis. 20:264-271. DOI.
  • Millington KA; Innes JA; Hackforth S; Hinks TS; Deeks JJ; Dosanjh DP; Guyot-Revol V; Gunatheesan R; et alKlenerman P; Lalvani A. (15 Apr 2007). Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load. J Immunol. 178:5217-5226.
  • Dinnes J; Deeks J; Kunst H; Gibson A; Cummins E; Waugh N; Drobniewski F; Lalvani A. (Jan 2007). A systematic review of rapid diagnostic tests for the detection of tuberculosis infection. HEALTH TECHNOL ASSES. 11:1-+.
  • Lalvani A; Millington K; Ewer K. (15 Jan 2007). Should individuals who are tuberculin skin test negative and positive to RD1-IFN-gamma assay receive preventive therapy? From the authors. AM J RESP CRIT CARE. 175:199-199.
  • Dinnes J; Deeks J; Kunst H; Gibson A; Cummins E; Waugh N; Drobniewski F; Lalvani A. (Jan 2007). A systematic review of rapid diagnostic tests for the detection of tuberculosis infection. Health Technol Assess. 11:1-196.
  • Richeldi L; Ewer K; Losi M; Bergamini BM; Millington K; Fabbri LM; Lalvani A. (Jan 2007). T-cell-based diagnosis of neonatal multidrug-resistant latent tuberculosis infection. Pediatrics. 119:e1-e5. DOI.
  • Gooding S; Chowdhury O; Hinks T; Richeldi L; Losi M; Ewer K; Millington K; Gunatheesan R; et alCerri S; McNally J; Lalvani A. (Mar 2007). Impact of a T cell-based blood test for tuberculosis infection on clinical decision-making in routine practice. J Infect. 54:e169-e174. DOI.
  • Jafari C; Ernst M; Kalsdorf B; Greinert U; Diel R; Kirsten D; Marienfeld K; Lalvani A; et alLange C. (1 Nov 2006). Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked immunospot. Am J Respir Crit Care Med. 174:1048-1054. DOI.
  • Ewer K; Millington KA; Deeks JJ; Alvarez L; Bryant G; Lalvani A. (1 Oct 2006). Dynamic antigen-specific T-cell responses after point-source exposure to Mycobacterium tuberculosis. Am J Respir Crit Care Med. 174:831-839. DOI.
  • Lalvani A; Guyot-Revol V. (1 Aug 2006). FoxP3 mRNA expression in regulatory T cells from patients with tuberculosis - Reply. AM J RESP CRIT CARE. 174:356-357.
  • Lalvani A; Bakir M; Millington KA; Dosanjh D; Soysal A. (Jul 2006). BCG: protection against infection with Mycobacterium tuberculosis - Reply. INT J TUBERC LUNG D. 10:826-826.
  • Guyot-Revol V; Innes JA; Hackforth S; Hinks T; Lalvani A. (1 Apr 2006). Regulatory T cells are expanded in blood and disease sites in patients with tuberculosis. Am J Respir Crit Care Med. 173:803-810. DOI.
  • Segal S; Pollard AJ; Watts C; Wainwright A; Lalvani A; Connell J. (Mar 2006). Osteomyelitis of the humerus complicating BCG vaccination. Arch Dis Child. 91:244. DOI.
  • Lalvani A; Bakir M; Millington KA; Dosanjh D; Soysal A. (4 Feb 2006). BCG and protection against Mycobacterium tuberculosis infection - Authors' reply. LANCET. 367:393-394.
  • Lalvani A; Bakir M; Millington KA; Dosanjh D; Soysal A. (4 Feb 2006). BCG and protection against Mycobacterium tuberculosis infection. Lancet. 367:391-392. DOI.
  • Richeldi L; Luppi M; Losi M; Luppi F; Potenza L; Roversi P; Cerri S; Millington KA; et alEwer K; Fabbri LM; Torelli G; Lalvani A. (Feb 2006). Diagnosis of occult tuberculosis in hematological malignancy by enumeration of antigen-specific T cells. Leukemia. 20:379-381. DOI.
  • Richeldi L; Ewer K; Losi M; Roversi P; Fabbri LM; Lalvani A. (Feb 2006). Repeated tuberculin testing does not induce false positive ELISPOT results. Thorax. 61:180. DOI.
  • Dheda K; Lalvani A; Miller RF; Scott G; Booth H; Johnson MA; Zumla A; Rook GA. (18 Nov 2005). Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count. AIDS. 19:2038-2041.
  • Shams H; Weis SE; Klucar P; Lalvani A; Moonan PK; Pogoda JM; Ewer K; Barnes PF. (1 Nov 2005). Enzyme-linked immunospot and tuberculin skin testing to detect latent tuberculosis infection. Am J Respir Crit Care Med. 172:1161-1168. DOI.
  • Soysal A; Millington KA; Bakir M; Dosanjh D; Aslan Y; Deeks JJ; Efe S; Staveley I; et alEwer K; Lalvani A. (22 Oct 2005). Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study. Lancet. 366:1443-1451. DOI.
  • Lalvani A; Richeldi L; Kunst H. (Jun 2005). Interferon gamma assays for tuberculosis. Lancet Infect Dis. 5:322-324. DOI.
  • Almeida D; Rodrigues C; Ashavaid TF; Lalvani A; Udwadia ZF; Mehta A. (15 Mar 2005). High incidence of the Beijing genotype among multidrug-resistant isolates of Mycobacterium tuberculosis in a tertiary care center in Mumbai, India. Clin Infect Dis. 40:881-886. DOI.
  • Wilkinson KA; Wilkinson RJ; Pathan A; Ewer K; Prakash M; Klenerman P; Maskell N; Davies R; et alPasvol G; Lalvani A. (1 Jan 2005). Ex vivo characterization of early secretory antigenic target 6-specific T cells at sites of active disease in pleural tuberculosis. CLINICAL INFECTIOUS DISEASES. 40:184-187.
  • Liebeschuetz S; Bamber S; Ewer K; Deeks J; Pathan AA; Lalvani A. (18 Dec 2004). Diagnosis of tuberculosis in South African children with a T-cell-based assay: a prospective cohort study. Lancet. 364:2196-2203. DOI.
  • Shams H; Klucar P; Weis SE; Lalvani A; Moonan PK; Safi H; Wizel B; Ewer K; et alNepom GT; Lewinsohn DM; Andersen P; Barnes PF. (1 Aug 2004). Characterization of a Mycobacterium tuberculosis peptide that is recognized by human CD4+ and CD8+ T cells in the context of multiple HLA alleles. J Immunol. 173:1966-1977.
  • Richeldi L; Ewer K; Losi M; Bergamini BM; Roversi P; Deeks J; Fabbri LM; Lalvani A. (1 Aug 2004). T cell-based tracking of multidrug resistant tuberculosis infection after brief exposure. Am J Respir Crit Care Med. 170:288-295. DOI.
  • Richeldi L; Ewer K; Losi M; Hansell DM; Roversi P; Fabbri LM; Lalvani A. (4 May 2004). Early diagnosis of subclinical multi drug-resistant tuberculosis. ANN INTERN MED. 140:709-713.
  • Liu XQ; Dosanjh D; Varia H; Ewer K; Cockle P; Pasvol G; Lalvani A. (May 2004). Evaluation of T-cell responses to novel RD1- and RD2-encoded Mycobacterium tuberculosis gene products for specific detection of human tuberculosis infection. INFECT IMMUN. 72:2574-2581. DOI.
  • Sester M; Sester U; Clauer P; Heine G; Mack U; Moll T; Sybrecht GW; Lalvani A; et alKöhler H. (May 2004). Tuberculin skin testing underestimates a high prevalence of latent tuberculosis infection in hemodialysis patients. Kidney Int. 65:1826-1834. DOI.
  • Lalvani A. (1 Mar 2004). Counting antigen-specific T cells: a new approach for monitoring response to tuberculosis treatment?. Clin Infect Dis. 38:757-759. DOI.
  • Lalvani A. (Nov 2003). Spotting latent infection: the path to better tuberculosis control. Thorax. 58:916-918.
  • Chapman A; Lalvani A. (15 Aug 2003). Response to letter from Jalba re: Rapid detection of Mycobacterium tuberculosis infection in HIV-infected Zambians by enumeration of RD1 gene product-specific T cells. AIDS. 17:1860-1861. DOI.
  • Almeida D; Rodrigues C; Udwadia ZF; Lalvani A; Gothi GD; Mehta P; Mehta A. (15 Jun 2003). Incidence of multidrug-resistant tuberculosis in urban and rural India and implications for prevention. Clin Infect Dis. 36:e152-e154. DOI.
  • Lalvani A; Ewer K; Bryant G; Monk P. (14 Jun 2003). Diagnosis of tuberculosis - Reply. LANCET. 361:2082-2083.
  • Ewer K; Deeks J; Alvarez L; Bryant G; Waller S; Andersen P; Monk P; Lalvani A. (5 Apr 2003). Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet. 361:1168-1173. DOI.
  • Cockle PJ; Gordon SV; Lalvani A; Buddle BM; Hewinson RG; Vordermeier HM. (Dec 2002). Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics. Infect Immun. 70:6996-7003.
  • Chapman AL; Munkanta M; Wilkinson KA; Pathan AA; Ewer K; Ayles H; Reece WH; Mwinga A; et alGodfrey-Faussett P; Lalvani A. (22 Nov 2002). Rapid detection of active and latent tuberculosis infection in HIV-positive individuals by enumeration of Mycobacterium tuberculosis-specific T cells. AIDS. 16:2285-2293.
  • Lalvani A. (15 Sep 2002). CD8 cytotoxic T cells and the development of new tuberculosis vaccines. Am J Respir Crit Care Med. 166:789-790.
  • Lalvani A. (15 May 2002). Improving tuberculin skin testing in HIV-infected individuals. AM J RESP CRIT CARE. 165:1452-1452.
  • Pathan AA; Wilkinson KA; Klenerman P; McShane H; Davidson RN; Pasvol G; Hill AVS; Lalvani A. (1 Nov 2001). Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: Associations with clinical disease state and effect of treatment. J IMMUNOL. 167:5217-5225.
  • Lalvani A; Pathan AA; Durkan H; Wilkinson KA; Whelan A; Deeks JJ; Reece WHH; Latif M; et alPasvol G; Hill AVS. (23 Jun 2001). Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. LANCET. 357:2017-2021.
  • Lalvani A; Pathan AA; McShane H; Wilkinson RJ; Latif M; Conlon CP; Pasvol G; Hill AVS. (Mar 2001). Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells. AM J RESP CRIT CARE. 163:824-828.
  • Lalvani A; Nagvenkar P; Udwadia Z; Pathan AA; Wilkinson KA; Shastri JS; Ewer K; Hill AV; et alMehta A; Rodrigues C. (1 Feb 2001). Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians. J Infect Dis. 183:469-477. DOI.
  • Bauer TM; Lalvani A; Fehrenbach J; Steffen I; Aponte JJ; Segovia R; Vila J; Philippczik G; et alSteinbrückner B; Frei R; Bowler I; Kist M. (17 Jan 2001). Derivation and validation of guidelines for stool cultures for enteropathogenic bacteria other than Clostridium difficile in hospitalized adults. JAMA. 285:313-319.
  • Pathan AA; Wilkinson KA; Wilkinson RJ; Latif M; McShane H; Pasvol G; Hill AVS; Lalvani A. (Sep 2000). High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M-tuberculosis-infected subjects without disease. EUR J IMMUNOL. 30:2713-2721.
  • Wilkinson RJ; Llewelyn M; Toossi Z; Patel P; Pasvol G; Lalvani A; Wright D; Latif M; et alDavidson RN. (19 Feb 2000). Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study. LANCET. 355:618-621.
  • Aidoo M; Lalvani A; Gilbert SC; Hu JT; Daubersies P; Hurt N; Whittle HC; Druihle P; et alHill AV. (Jan 2000). Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3. Infect Immun. 68:227-232.
  • Lalvani A; Moris P; Voss G; Pathan AA; Kester KE; Brookes R; Lee E; Koutsoukos M; et alPlebanski M; Delchambre M; Flanagan KL; Carton C; Slaoui M; Van Hoecke C; Ballou WR; Hill AV; Cohen J. (Nov 1999). Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine. J Infect Dis. 180:1656-1664. DOI.
  • Cooke GS; Lalvani A; Gleeson FV; Conlon CP. (Oct 1999). Acute pulmonary schistosomiasis in travelers returning from Lake Malawi, sub-Saharan Africa. Clin Infect Dis. 29:836-839. DOI.
  • Wilkinson RJ; Zhu X; Wilkinson KA; Lalvani A; Ivanyi J; Pasvol G; Vordermeier HM. (Dec 1998). 38 000 MW antigen-specific major histocompatibility complex class I restricted interferon-gamma-secreting CD8+ T cells in healthy contacts of tuberculosis. Immunology. 95:585-590.
  • Lalvani A; Hill AV. (Nov 1998). Cytotoxic T-lymphocytes against malaria and tuberculosis: from natural immunity to vaccine design. Clin Sci (Lond). 95:531-538.
  • Ockenhouse CF; Sun PF; Lanar DE; Wellde BT; Hall BT; Kester K; Stoute JA; Magill A; et alKrzych U; Farley L; Wirtz RA; Sadoff JC; Kaslow DC; Kumar S; Church LW; Crutcher JM; Wizel B; Hoffman S; Lalvani A; Hill AV; Tine JA; Guito KP; de Taisne C; Anders R; Ballou WR. (Jun 1998). Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria. J Infect Dis. 177:1664-1673.
  • Lalvani A; Brookes R; Wilkinson RJ; Malin AS; Pathan AA; Andersen P; Dockrell H; Pasvol G; et alHill AV. (6 Jan 1998). Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 95:270-275.
  • Lalvani A; Dong T; Ogg G; Patham AA; Newell H; Hill AV; McMichael AJ; Rowland-Jones S. (15 Dec 1997). Optimization of a peptide-based protocol employing IL-7 for in vitro restimulation of human cytotoxic T lymphocyte precursors. J Immunol Methods. 210:65-77.
  • Lalvani A; Brookes R; Hambleton S; Britton WJ; Hill AV; McMichael AJ. (15 Sep 1997). Rapid effector function in CD8+ memory T cells. J Exp Med. 186:859-865.
  • Aidoo M; Lalvani A; Whittle HC; Hill AV; Robson KJ. (May 1997). Recombinant vaccinia viruses for the characterization of Plasmodium falciparum-specific cytotoxic T lymphocytes: recognition of processed antigen despite limited re-stimulation efficacy. Int Immunol. 9:731-737.
  • Faux JA; Moffatt MF; Lalvani A; Dekker J; Warrell DA; Cookson WO. (May 1997). Sensitivity to bee and wasp venoms: association with specific IgE responses to the bee and wasp venom and HLA DRB1 and DPB1. Clin Exp Allergy. 27:578-583.
  • Lalvani A; Newton P; Conlon CP. (Mar 1997). Salmonella enteritidis and acute renal failure: Report of five cases and review. INFECT DIS CLIN PRAC. 6:193-195.
  • Lalvani A; Shastri JS. (18 May 1996). HIV epidemic in India: opportunity to learn from the past. Lancet. 347:1349-1350.
  • Lalvani A; Hurt N; Aidoo M; Kibatala P; Tanner M; Hill AV. (Apr 1996). Cytotoxic T lymphocytes to Plasmodium falciparum epitopes in an area of intense and perennial transmission in Tanzania. Eur J Immunol. 26:773-779. DOI.
  • Newton P; Lalvani A; Conlon CP. (Jan 1996). Psittacosis associated with bilateral 4th cranial nerve palsies. J Infect. 32:63-65.
  • Aidoo M; Lalvani A; Allsopp CE; Plebanski M; Meisner SJ; Krausa P; Browning M; Morris-Jones S; et alGotch F; Fidock DA. (22 Apr 1995). Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria. Lancet. 345:1003-1007.
  • O'Callaghan CA; Wells AU; Lalvani A; Dhillon PD; Hansell DM; Mitchell DN. (Dec 1994). Effective use of cyclosporin in sarcoidosis: a treatment strategy based on computed tomography scanning. Eur Respir J. 7:2255-2256.
  • Hill AV; Yates SN; Allsopp CE; Gupta S; Gilbert SC; Lalvani A; Aidoo M; Davenport M; et alPlebanski M. (29 Nov 1994). Human leukocyte antigens and natural selection by malaria. Philos Trans R Soc Lond B Biol Sci. 346:379-385. DOI.
  • Lalvani A; Aidoo M; Allsopp CE; Plebanski M; Whittle HC; Hill AV. (Jul 1994). An HLA-based approach to the design of a CTL-inducing vaccine against Plasmodium falciparum. Res Immunol. 145:461-468.

Conferences

  • Pareek M; Bond M; Shorey J; Seneviratne S; Lalvani A; Kon OM. COMMUNITY-BASED EVALUATION OF IMMIGRANT TB SCREENING USING INTERFERON GAMMA RELEASE ASSAYS AND TUBERCULIN SKIN TESTING: YIELDS AND COST-EFFECTIVENESS. 66:A20-A20. (Dec 2011). DOI.
  • Almond MH; O'Donoghue M; Drey N; Seneviratne S; Lalvani A; Wickremasinghe M; Kon OM. INTERFERON-GAMMA RELEASE ASSAY (IGRA) CONVERSION, REVERSION AND IMPLICATIONS FOR THE DIAGNOSIS OF LATENT TUBERCULOSIS INFECTION USING A MULTIMODALITY APPROACH: A RETROSPECTIVE, OBSERVATIONAL STUDY WITHIN A CENTRAL LONDON TB CENTRE. 66:A72-A72. (Dec 2011). DOI.
  • Asgheddi M; Connell DW; Nooredinvand HA; Abdullah M; O'Donoghue M; Campbell L; Lalvani A; Wickremasinghe M; et alKhan S; Kon OM. THE PREVALENCE OF VIRAL HEPATITIS IN PATIENTS UNDERGOING ANTI-TUBERCULOUS THERAPY. 66:A93-A94. (Dec 2011). DOI.
  • Dhasmana DJ; Bradley CJ; George P; Connell DW; Molyneaux P; Singanayagam A; Lalvani A; Jepson A; et alKon OM; Cooke GS. GENEXPERT MTB.RIF ASSAY IMPROVES THE DIAGNOSTIC YIELD OF EBUS-TBNA IN SMEAR-NEGATIVE INTRA-THORACIC TUBERCULOUS LYMPHADENOPATHY. 66:A75-A75. (Dec 2011). DOI.
  • Pollock KM; Montamat-Sicotte D; Cooke G; Kapembwa M; Kon OM; Taylor GP; Lalvani A. POLYFUNCTIONAL T CELLS REVEAL THE SPECTRUM OF TUBERCULOSIS IN HIV CO-INFECTION THROUGH THE IDENTIFICATION OF IMMUNOLOGICAL CORRELATES OF LATENT AND ACTIVE DISEASE. 66:A22-A23. (Dec 2011). DOI.
  • Sridhar S; Begom S; Bermingham A; Roberts K; Barclay W; Openshaw P; Lalvani A. Predominance of heterosubtypic IFN-gamma-only-secreting effector memory T cells in pandemic H1N1 naive adults. 135:65-65. (Dec 2011).
  • Hingley-Wilson S; Connell D; Pollock K; Min KO; Jacobs W; Lalvani A. Fractalkine production mediates virulence-associated monocyte recruitment and Mycobacterium tuberculosis infection. 135:167-167. (Dec 2011).
  • Bwalya AG; Stapleton P; Phiri P; Montamat SD; Hingley WS; Lalvani A; Tasdemir D. Screening of Zambian Ficus species for antibacterial and antimycobacterial activity. 77:1383-1383. (Aug 2011).
  • Asgheddi M; Abdullah M; ODonoghue M; Campbell L; Lalvani A; Wickremasinghe M; Kon OM; Khan SA. PREVALENCE OF VIRAL HEPATITIS IN PATIENTS UNDERGOING ANTI-TUBERCULOSIS THERAPY IN WEST LONDON. 52:685A-686A. (Oct 2010).
  • Pareek M; Watson JP; Kon OM; Woltmann G; Lalvani A. PREVALENCE OF LATENT TUBERCULOSIS INFECTION IN IMMIGRANTS TO THE UK: FINDINGS FROM A MULTI-CENTRE STUDY. 65:A5-A6. (Dec 2010). DOI.
  • Singanayagam A; George P; Connell D; Kaneria S; Dhariwal J; Molyneaux P; Wickremasinghe M; Lalvani A; et alWright A; Kon OM. CHARACTERISATION OF TUBERCULOUS MEDIASTINAL LYMPHADENOPATHY ON CT AND CORRELATION WITH BIOMARKERS AND CHEST RADIOGRAPH FINDINGS. 65:A148-A149. (Dec 2010). DOI.
  • Sridhar S; Begom S; Bermingham A; Bremang S; Magtoto M; Grass L; Potiphar L; Openshaw P; et alLalvani A. Cross-reactive T cells to pandemic influenza H1N1 are predominantly of an effector phenotype. 131:176-176. (Dec 2010).
  • Hingley-Wilson S; Kon OM; Hsu T; Jacobs W; Lalvani A. Mycobacterium tuberculosis RD1 is a requisite for virulence-associated cellular recruitment. 131:173-173. (Dec 2010).
  • Montamat-Sicotte D; Millington K; Willcox CR; Hingley-Wilson S; Hackforth S; Innes J; Kon OM; Minnikin DE; et alBesra GS; Willcox BE; Lalvani A. Mycolic acid-specific T-cells in human tuberculosis are dynamically related to antigen load and exhibit memory expansion after cure. 131:171-171. (Dec 2010).
  • Pollock K; Montamat-Sicotte D; Cooke G; Kapembwa M; Kon OM; Taylor GP; Lalvani A. Exploring polyfunctional T cells in HIV and Mycobacterium tuberculosis co-infection; multi-colour flow for a multi-faceted problem. 131:147-147. (Dec 2010).
  • Shora F; Cook G; Lewis J; Lalvani A; Wickremasinghe M; Kon OM. ROLE FOR 2-[FLUORINE-18]FLUORO-2-DEOXY-D-GLUCOSE (FDG) POSITRON EMISSION TOMOGRAPHY SCANNING IN ACTIVE TUBERCULOSIS. 64:A125-A125. (Dec 2009). DOI.
  • Pareek M; Abubakar I; White PJ; Garnett GP; Lalvani A. INCONSISTENT AND INCOHERENT METHODS OF SCREENING NEW ENTRANTS TO THE UK FOR TUBERCULOSIS. 64:A106-A107. (Dec 2009). DOI.
  • Connell DW; Nathavitharana R; Jepson A; Deeab D; Dhawan R; O'Donoghue M; Molyneaux P; Lalvani A; et alKon OM. PROLONGED INFECTIVITY IN URBAN UK PATIENTS WITH TB: AN UNDERAPPRECIATED PROBLEM?. 64:A126-A126. (Dec 2009). DOI.
  • Molyneaux PL; Muttardi K; Connell DW; Wickremasinghe M; Lalvani A; Jepson A; McCarthy J; Wright C; et alKon OM. CLINICAL UTILITY OF ENDOBRONCHIAL ULTRASOUND-GUIDED TRANSBRONCHIAL NEEDLE ASPIRATION (EBUS-TBNA) FOR THE DIAGNOSIS OF MEDIASTINAL TUBERCULOUS LYMPHADENITIS. 64:A124-A125. (Dec 2009). DOI.
  • Montamat-Sicotte D; Millington K; Willcox C; Besra GS; Innes J; Hackforth S; Willcox BE; Lalvani A. Monitoring of mycolic acid-specific T cell responses in TB patients during treatment. 125:139-139. (Dec 2008).
  • Lalvani A; Millington KA. Screening for tuberculosis infection prior to initiation of anti-TNF therapy. 8:147-152. (Dec 2008). DOI.
  • Connell DW; Lalvani A; O'Donoghue M; Kon OM. TUBERCULOSIS-ASSOCIATED VITAMIN D DEFICIENCY IS NOT SECONDARY TO MYCOBACTERIAL DISEASE ACTIVITY. 63:A113-A113. (Dec 2008).
  • Hinks TSC; Dosanjh DPS; Innes JA; Pasvol G; Hackforth S; Varia H; Millington KA; Gunatheesan R; et alDeeks JJ; Lalvani A. FREQUENCY OF MYCOBACTERIUM TUBERCULOSIS ANTIGEN-SPECIFIC IFN-Gamma-SECRETING T CELLS CORRELATES WITH PRESENCE OF PATHOLOGY IN TUBERCULOSIS. 63:A63-A64. (Dec 2008).
  • Hinks TSC; Dosanjh DPS; Innes JA; Deeks J; Pasvol G; Hackforth S; Varia H; Liu XQ; et alMillington K; Gunatheesan R; Guyot-Revol V; Lalvani A. The role of T cell based interferon-gamma release assays in the evaluation of patients with suspected active tuberculosis. Winter Meeting of the British-Thoracic-Society. 62:A22-A22. (Dec 2007).
  • Di Felice A; Losi M; Roversi P; Cerri S; Debbi A; Ferrari F; Ferramosca E; Millington K; et alCappelli G; Albertazzi A; Fabbri LM; Lalvani A; Richeldi L. Comparison of the tuberculin skin test and the elispot blood test for the diagnosis of latent tuberculosis infection in pre-transplant dialysis patients. 6th American Transplant Congress. 5:289-290. (May 2005).
  • Di Felice A; Losi M; Roversi P; Cerri S; Debbi A; Ferrari F; Ferramosca E; Ravera F; et alMillington K; Cappelli G; Lucchi L; Albertazzi A; Fabbri LM; Lalvani A; Richeldi L. Empoyment of the ELISPOT blood test for the diagnosis of latent tuberculosis infection in dialysis patients awaiting renal transplantation. 42nd Annual Meeting of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA). 20:V180-V180. (Jun 2005).
  • Shams H; Klucar P; Weis SE; Lalvani A; Safi H; Wizel B; Moonan PK; Ewer K; et alBarnes PF. Identification of M-Tuberculosis peptides that are recognized by human CD4+ and CD8+ T-cells from persons expressing different HLA alleles. 17:C27-C27. (14 Apr 2003).
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