Publications

Journals

• Andersson HM; Siegerink B; Luken BM; Crawley JT; Algra A; Lane DA; Rosendaal FR. (9 Feb 2012). High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women. Blood. 119:1555-1560. DOI.
• Froehlich-Zahnd R; George JN; Vesely SK; Terrell DR; Aboulfatova K; Dong JF; Luken BM; Voorberg J; et alBudde U; Sulzer I; Lämmle B; Kremer Hovinga JA. (Feb 2012). Evidence for a role of anti-ADAMTS13 autoantibodies despite normal ADAMTS13 activity in recurrent thrombotic thrombocytopenic purpura. Haematologica. 97:297-303. DOI.
• Crawley JT; de Groot R; Xiang Y; Luken BM; Lane DA. (22 Sep 2011). Unraveling the scissile bond: how ADAMTS13 recognizes and cleaves von Willebrand factor. Blood. 118:3212-3221. DOI.
• Pos W; Luken BM; Sorvillo N; Hovinga JA; Voorberg J. (Jul 2011). Humoral immune response to ADAMTS13 in acquired thrombotic thrombocytopenic purpura. J Thromb Haemost. 9:1285-1291. DOI.
• Luken BM; Winn LY; Emsley J; Lane DA; Crawley JT. (10 Jun 2010). The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function. Blood. 115:4910-4913. DOI.
• Andersson HM; Arantes MJ; Crawley JT; Luken BM; Tran S; Dahlbäck B; Lane DA; Rezende SM. (10 Jun 2010). Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain. Blood. 115:4878-4885. DOI.
• Pos W; Crawley JT; Fijnheer R; Voorberg J; Lane DA; Luken BM. (25 Feb 2010). An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF. Blood. 115:1640-1649. DOI.
• Crawley JTB; de Groot R; Luken BM. (1 Dec 2009). Circulating ADAMTS-13-von Willebrand factor complexes: an enzyme on demand. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 7:2085-2087. Author weblink DOI.
• Pos W; Luken BM; Hovinga JAK; Turenhout EAM; Scheiflinger F; Dong J-F; Fijnheer R; Voorberg J. (1 Mar 2009). VH1-69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 7:421-428. Author weblink DOI.
• Luken BM. (1 Jul 2008). Extracellular control of VWF multimer size and thiol-disulfide exchange. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 6:1131-1134. Author weblink DOI.
• Riksen NP; Luken BM; Klasen IS; Voorberg J; Crama N; van Deuren M. (Jul 2007). Antibodies against the CUB1-2 domains of ADAMTS13 in a patient with benign monoclonal gammopathy: no causal relationship. Haematologica. 92:e74-e76.
• Tjernberg P; Vos HL; Spaargaren-van Riel CC; Luken BM; Voorberg J; Bertina RM; Eikenboom JC. (Dec 2006). Differential effects of the loss of intrachain- versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand disease. Thromb Haemost. 96:717-724.
• Luken BM; Kaijen PH; Turenhout EA; Kremer Hovinga JA; van Mourik JA; Fijnheer R; Voorberg J. (Nov 2006). Multiple B-cell clones producing antibodies directed to the spacer and disintegrin/thrombospondin type-1 repeat 1 (TSP1) of ADAMTS13 in a patient with acquired thrombotic thrombocytopenic purpura. J Thromb Haemost. 4:2355-2364. DOI.
• Luken BM; Turenhout EA; Kaijen PH; Greuter MJ; Pos W; van Mourik JA; Fijnheer R; Voorberg J. (Sep 2006). Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP. Thromb Haemost. 96:295-301. DOI.
• Luken BM; Turenhout EA; Hulstein JJ; Van Mourik JA; Fijnheer R; Voorberg J. (Feb 2005). The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura. Thromb Haemost. 93:267-274. DOI.