Professor Brian G Spratt CBE FRS FMedSci

Publications


Journals

  • Dale J; Price EP; Hornstra H; Busch JD; Mayo M; Godoy D; Wuthiekanun V; Baker A; et alFoster JT; Wagner DM; Tuanyok A; Warner J; Spratt BG; Peacock SJ; Currie BJ; Keim P; Pearson T. (Dec 2011). Epidemiological tracking and population assignment of the non-clonal bacterium, Burkholderia pseudomallei. PLoS Negl Trop Dis. 5:e1381. DOI.
  • Ahmed A; Thaipadungpanit J; Boonsilp S; Wuthiekanun V; Nalam K; Spratt BG; Aanensen DM; Smythe LD; et alAhmed N; Feil EJ; Hartskeerl RA; Peacock SJ. (Nov 2011). Comparison of two multilocus sequence based genotyping schemes for Leptospira species. PLoS Negl Trop Dis. 5:e1374. DOI.
  • Hyams C; Opel S; Hanage W; Yuste J; Bax K; Henriques-Normark B; Spratt BG; Brown JS. (2011). Effects of Streptococcus pneumoniae strain background on complement resistance. PLoS One. 6:e24581. DOI.
  • Cheng L; Connor TR; Aanensen DM; Spratt BG; Corander J. (26 Jul 2011). Bayesian semi-supervised classification of bacterial samples using MLST databases. BMC BIOINFORMATICS. 12. DOI.
  • Hampton V; Kaestli M; Mayo M; Choy JL; Harrington G; Richardson L; Benedict S; Noske R; et alGarnett ST; Godoy D; Spratt BG; Currie BJ. (Jul 2011). Melioidosis in Birds and Burkholderia pseudomallei Dispersal, Australia. Emerg Infect Dis. 17:1310-1312. DOI.
  • Mayo M; Kaesti M; Harrington G; Cheng AC; Ward L; Karp D; Jolly P; Godoy D; et alSpratt BG; Currie BJ. (Jul 2011). Burkholderia pseudomallei in unchlorinated domestic bore water, Tropical Northern Australia. Emerg Infect Dis. 17:1283-1285. DOI.
  • Mukhopadhyay C; Kaestli M; Vandana KE; Sushma K; Mayo M; Richardson L; Tuanyok A; Keim P; et alGodoy D; Spratt BG; Currie BJ. (Jul 2011). Molecular characterization of clinical Burkholderia pseudomallei isolates from India. Am J Trop Med Hyg. 85:121-123. DOI.
  • Nghia HD; Tu LETP; Wolbers M; Thai CQ; Hoang NV; Nga TV; Thao LETP; Phu NH; et alChau TT; Sinh DX; Diep TS; Hang HT; Chau NV; Chinh NT; Dung NV; Hoa NT; Spratt BG; Hien TT; Farrar J; Schultsz C. (2011). Risk factors of Streptococcus suis infection in Vietnam. A case-control study. PLoS One. 6:e17604. DOI.
  • Enright MC; Spratt BG. (28 Jan 2011). Genomics. The genomic view of bacterial diversification. Science. 331:407-409. DOI.
  • Mavroidi A; Tzelepi E; Siatravani E; Godoy D; Miriagou V; Spratt BG. (Apr 2011). Analysis of emergence of quinolone-resistant gonococci in Greece by combined use of Neisseria gonorrhoeae multiantigen sequence typing and multilocus sequence typing. J Clin Microbiol. 49:1196-1201. DOI.
  • Lima JB; Ribeiro GS; Cordeiro SM; Gouveia EL; Salgado K; Spratt BG; Godoy D; Reis MG; et alKo AI; Reis JN. (15 Nov 2010). Poor clinical outcome for meningitis caused by Haemophilus influenzae serotype A strains containing the IS1016-bexA deletion. J Infect Dis. 202:1577-1584. DOI.
  • Grundmann H; Aanensen DM; van den Wijngaard CC; Spratt BG; Harmsen D; Friedrich AW; European Staphylococcal Reference Laboratory Working Group. (Jan 2010). Geographic distribution of Staphylococcus aureus causing invasive infections in Europe: a molecular-epidemiological analysis. PLoS Med. 7:e1000215. DOI.
  • Aanensen DM; Huntley DM; Feil EJ; al-Own F; Spratt BG. (16 Sep 2009). EpiCollect: Linking Smartphones to Web Applications for Epidemiology, Ecology and Community Data Collection. PLOS ONE. 4. DOI.
  • Dean D; Bruno WJ; Wan R; Gomes JP; Devignot S; Mehari T; de Vries HJC; Morre SA; et alMyers G; Read TD; Spratt BG. (Sep 2009). Predicting Phenotype and Emerging Strains among Chlamydia trachomatis Infections. EMERG INFECT DIS. 15:1385-1394. DOI.
  • Holden MT; Hauser H; Sanders M; Ngo TH; Cherevach I; Cronin A; Goodhead I; Mungall K; et alQuail MA; Price C; Rabbinowitsch E; Sharp S; Croucher NJ; Chieu TB; Mai NT; Diep TS; Chinh NT; Kehoe M; Leigh JA; Ward PN; Dowson CG; Whatmore AM; Chanter N; Iversen P; Gottschalk M; Slater JD; Smith HE; Spratt BG; Xu J; Ye C; Bentley S; Barrell BG; Schultsz C; Maskell DJ; Parkhill J. (2009). Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis. PLoS One. 4:e6072. DOI.
  • Bilek N; Ison CA; Spratt BG. (Mar 2009). Relative contributions of recombination and mutation to the diversification of the opa gene repertoire of Neisseria gonorrhoeae. J Bacteriol. 191:1878-1890. DOI.
  • Holden MTG; Heather Z; Paillot R; Steward KF; Webb K; Ainslie F; Jourdan T; Bason NC; et alHolroyd NE; Mungall K; Quail MA; Sanders M; Simmonds M; Willey D; Brooks K; Aanensen DM; Spratt BG; Jolley KA; Maiden MCJ; Kehoe M; Chanter N; Bentley SD; Robinson C; Maskell DJ; Parkhill J; Waller AS. (Mar 2009). Genomic Evidence for the Evolution of Streptococcus equi: Host Restriction, Increased Virulence, and Genetic Exchange with Human Pathogens. PLOS PATHOG. 5. DOI.
  • Fraser C; Alm EJ; Polz MF; Spratt BG; Hanage WP. (6 Feb 2009). The bacterial species challenge: making sense of genetic and ecological diversity. Science. 323:741-746. DOI.
  • Currie BJ; Haslem A; Pearson T; Hornstra H; Leadem B; Mayo M; Gal D; Ward L; et alGodoy D; Spratt BG; Keim P. (Feb 2009). Identification of Melioidosis Outbreak by Multilocus Variable Number Tandem Repeat Analysis. EMERG INFECT DIS. 15:169-174. DOI.
  • Bishop CJ; Aanensen DM; Jordan GE; Kilian M; Hanage WP; Spratt BG. (26 Jan 2009). Assigning strains to bacterial species via the internet. BMC BIOL. 7. DOI.
  • Reis JN; Palma T; Ribeiro GS; Pinheiro RM; Ribeiro CT; Cordeiro SM; da Silva HP; Moschioni M; et alThompson TA; Spratt B; Riley LW; Barocchi MA; Reis MG; Ko AI. (Sep 2008). Transmission of Streptococcus pneumoniae in an urban slum community. J INFECTION. 57:204-213. DOI.
  • Nghia HDT; Hoa NT; Linh LD; Campbell J; Diep TS; Chau NVV; Mai NTH; Hien TT; et alSpratt B; Farrar J; Schultsz C. (Jan 2008). Human case of Streptococcus suis serotype 16 infection. EMERG INFECT DIS. 14:155-157.
  • Cheng AC; Ward L; Godoy D; Norton R; Mayo M; Gal D; Spratt BG; Currie BJ. (Jan 2008). Genetic diversity of Burkholderia pseudomallei isolates in Australia. J Clin Microbiol. 46:249-254. DOI.
  • Mavroidi A; Aanensen DM; Godoy D; Skovsted IC; Kaltoft MS; Reeves PR; Bentley SD; Spratt BG. (Nov 2007). Genetic relatedness of the Streptococcus pneumoniae capsular biosynthetic loci. J Bacteriol. 189:7841-7855. DOI.
  • Aanensen DM; Mavroldi A; Bentley SD; Reeves PR; Spratt BG. (Nov 2007). Predicted functions and linkage Specificities of the products of the Streptococcus pneumoniae capsular biosynthetic loci. J BACTERIOL. 189:7856-7876. DOI.
  • Mavroidi A; Aanensen DM; Godoy D; Skovsted IC; Kaltoft MS; Reeves PR; Bentley SD; Spratt BG. (Nov 2007). Genetic relatedness of the Streptococcus pneumoniae capsular Biosynthetic loci. J BACTERIOL. 189:7841-7855. DOI.
  • Bishop EJ; Shilton C; Benedict S; Kong F; Gilbert GL; Gal D; Godoy D; Spratt BG; et alCurrie BJ. (Nov 2007). Necrotizing fasciitis in captive juvenile Crocodylus porosus caused by Streptococcus agalactiae: an outbreak and review of the animal and human literature. Epidemiol Infect. 135:1248-1255. DOI.
  • Bilek N; Martin IM; Bell G; Kinghorn GR; Ison CA; Spratt BG. (Nov 2007). Concordance between Neisseria gonorrhoeae genotypes recovered from known sexual contacts. J Clin Microbiol. 45:3564-3567. DOI.
  • Currie BJ; Thomas AD; Godoy D; Dance DA; Cheng AC; Ward L; Mayo M; Pitt TL; et alSpratt BG. (Nov 2007). Australian and Thai isolates of Burkholderia pseudomallei are distinct by multilocus sequence typing: revision of a case of mistaken identity. J Clin Microbiol. 45:3828-3829. DOI.
  • Risley CL; Ward H; Choudhury B; Bishop CJ; Fenton KA; Spratt BG; Ison CA; Ghani AC. (1 Oct 2007). Geographical and demographic clustering of gonorrhoea in London. SEX TRANSM INFECT. 83:481-487. DOI.
  • Fraser C; Hanage WP; Spratt BG. (26 Jan 2007). Recombination and the nature of bacterial speciation. Science. 315:476-480. DOI.
  • Turner KM; Hanage WP; Fraser C; Connor TR; Spratt BG. (2007). Assessing the reliability of eBURST using simulated populations with known ancestry. BMC Microbiol. 7:30. DOI.
  • Currie BJ; Gal D; Mayo M; Ward L; Godoy D; Spratt BG; LiPuma JJ. (2007). Using BOX-PCR to exclude a clonal outbreak of melioidosis. BMC Infect Dis. 7:68. DOI.
  • Glass MB; Gee JE; Steigerwalt AG; Cavuoti D; Barton T; Hardy RD; Godoy D; Spratt BG; et alClark TA; Wilkins PP. (Dec 2006). Pneumonia and septicemia caused by Burkholderia thailandensis in the United States. J Clin Microbiol. 44:4601-4604. DOI.
  • Spratt BG; Staley JT; Fisher MC. (29 Nov 2006). Introduction: species and speciation in micro-organisms. Philos Trans R Soc Lond B Biol Sci. 361:1897-1898. Publisher weblink DOI.
  • Hanage WP; Fraser C; Spratt BG. (29 Nov 2006). Sequences, sequence clusters and bacterial species. Philos Trans R Soc Lond B Biol Sci. 361:1917-1927. DOI.
  • Hanage WP; Spratt BG; Turner KM; Fraser C. (29 Nov 2006). Modelling bacterial speciation. Philos Trans R Soc Lond B Biol Sci. 361:2039-2044. DOI.
  • Choudhury B; Risley CL; Ghani AC; Bishop CJ; Ward H; Fenton KA; Ison CA; Spratt BG. (8 Jul 2006). Identification of individuals with gonorrhoea within sexual networks: a population-based study. Lancet. 368:139-146. DOI.
  • Vesaratchavest M; Tumapa S; Day NP; Wuthiekanun V; Chierakul W; Holden MT; White NJ; Currie BJ; et alSpratt BG; Feil EJ; Peacock SJ. (Jul 2006). Nonrandom distribution of Burkholderia pseudomallei clones in relation to geographical location and virulence. J Clin Microbiol. 44:2553-2557. DOI.
  • Jones N; Oliver KA; Barry J; Harding RM; Bisharat N; Spratt BG; Peto T; Crook DW; et alOxford Grp B Streptococus Consorti. (1 Apr 2006). Enhanced invasiveness of bovine-derived neonatal sequence type 17 group B Streptococcus is independent of capsular serotype. CLIN INFECT DIS. 42:915-924.
  • Hanage WP; Fraser C; Spratt BG. (21 Mar 2006). The impact of homologous recombination on the generation of diversity in bacteria. J Theor Biol. 239:210-219. DOI.
  • Bentley SD; Aanensen DM; Mavroidi A; Saunders D; Rabbinowitsch E; Collins M; Donohoe K; Harris D; et alMurphy L; Quail MA; Samuel G; Skovsted IC; Kaltoft MS; Barrell B; Reeves PR; Parkhill J; Spratt BG. (Mar 2006). Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. PLoS Genet. 2:e31. DOI.
  • Hanage WP; Kaijalainen T; Saukkoriipi A; Rickcord JL; Spratt BG. (Mar 2006). A successful, diverse disease-associated lineage of nontypeable pneumococci that has lost the capsular biosynthesis locus. J Clin Microbiol. 44:743-749. DOI.
  • Le Hello S; Currie BJ; Godoy D; Spratt BG; Mikulski M; Lacassin F; Garin B. (Oct 2005). Melioidosis in New Caledonia. Emerg Infect Dis. 11:1607-1609.
  • Martin IM; Ison CA; Aanensen DM; Fenton KA; Spratt BG. (1 Oct 2005). Changing epidemiologic profile of quinolone-resistant Neisseria gonorrhoeae in London. J Infect Dis. 192:1191-1195. DOI.
  • Palmer HM; Young H; Martin IM; Ison CA; Spratt BG. (Oct 2005). The epidemiology of ciprofloxacin resistant isolates of Neisseria gonorrhoeae in Scotland 2002: a comparison of phenotypic and genotypic analysis. Sex Transm Infect. 81:403-407. DOI.
  • Abbott JC; Aanensen DM; Rutherford K; Butcher S; Spratt BG. (15 Sep 2005). WebACT--an online companion for the Artemis Comparison Tool. Bioinformatics. 21:3665-3666. DOI.
  • Hanage WP; Kaijalainen T; Herva E; Saukkoriipi A; Syrjänen R; Spratt BG. (Sep 2005). Using multilocus sequence data to define the pneumococcus. J Bacteriol. 187:6223-6230. DOI.
  • Gevers D; Cohan FM; Lawrence JG; Spratt BG; Coenye T; Feil EJ; Stackebrandt E; Van de Peer Y; et alVandamme P; Thompson FL; Swings J. (Sep 2005). Opinion: Re-evaluating prokaryotic species. Nat Rev Microbiol. 3:733-739. DOI.
  • Luan SL; Granlund M; Sellin M; Lagergård T; Spratt BG; Norgren M. (Aug 2005). Multilocus sequence typing of Swedish invasive group B streptococcus isolates indicates a neonatally associated genetic lineage and capsule switching. J Clin Microbiol. 43:3727-3733. DOI.
  • Aanensen DM; Spratt BG. (1 Jul 2005). The multilocus sequence typing network: mlst.net. NUCLEIC ACIDS RES. 33:W728-W733. DOI.
  • McGregor KF; Spratt BG. (Apr 2005). Identity and prevalence of multilocus sequence typing-defined clones of group A streptococci within a hospital setting. J Clin Microbiol. 43:1963-1967. DOI.
  • Hanage WP; Fraser C; Spratt BG. (2005). Fuzzy species among recombinogenic bacteria. BMC Biol. 3:6. DOI.
  • Fraser C; Hanage WP; Spratt BG. (8 Feb 2005). Neutral microepidemic evolution of bacterial pathogens. Proc Natl Acad Sci U S A. 102:1968-1973. DOI.
  • Hanage WP; Kaijalainen TH; Syrjänen RK; Auranen K; Leinonen M; Mäkelä PH; Spratt BG. (Jan 2005). Invasiveness of serotypes and clones of Streptococcus pneumoniae among children in Finland. Infect Immun. 73:431-435. DOI.
  • Porat N; Arguedas A; Spratt BG; Trefler R; Brilla E; Loaiza C; Godoy D; Bilek N; et alDagan R. (15 Dec 2004). Emergence of penicillin-nonsusceptible Streptococcus pneumoniae clones expressing serotypes not present in the antipneumococcal conjugate vaccine. J Infect Dis. 190:2154-2161. DOI.
  • Spratt BG; Hanage WP; Li B; Aanensen DM; Feil EJ. (15 Dec 2004). Displaying the relatedness among isolates of bacterial species -- the eBURST approach. FEMS Microbiol Lett. 241:129-134. DOI.
  • Spratt BG. (Dec 2004). John Maynard Smith (1920-2004). Infect Genet Evol. 4:297-300.
  • Cheng AC; Godoy D; Mayo M; Gal D; Spratt BG; Currie BJ. (Dec 2004). Isolates of Burkholderia pseudomallei from Northern Australia are distinct by multilocus sequence typing, but strain types do not correlate with clinical presentation. J Clin Microbiol. 42:5477-5483. DOI.
  • Mavroidi A; Godoy D; Aanensen DM; Robinson DA; Hollingshead SK; Spratt BG. (Dec 2004). Evolutionary genetics of the capsular locus of serogroup 6 pneumococci. J Bacteriol. 186:8181-8192. DOI.
  • Brueggemann AB; Peto TE; Crook DW; Butler JC; Kristinsson KG; Spratt BG. (1 Oct 2004). Temporal and geographic stability of the serogroup-specific invasive disease potential of Streptococcus pneumoniae in children. J Infect Dis. 190:1203-1211. DOI.
  • Bougnoux ME; Aanensen DM; Morand S; Théraud M; Spratt BG; d'Enfert C. (Sep 2004). Multilocus sequence typing of Candida albicans: strategies, data exchange and applications. Infect Genet Evol. 4:243-252. DOI.
  • McGregor KF; Spratt BG; Kalia A; Bennett A; Bilek N; Beall B; Bessen DE. (Jul 2004). Multilocus sequence typing of Streptococcus pyogenes representing most known emm types and distinctions among subpopulation genetic structures. J Bacteriol. 186:4285-4294. DOI.
  • Holden MT; Feil EJ; Lindsay JA; Peacock SJ; Day NP; Enright MC; Foster TJ; Moore CE; et alHurst L; Atkin R; Barron A; Bason N; Bentley SD; Chillingworth C; Chillingworth T; Churcher C; Clark L; Corton C; Cronin A; Doggett J; Dowd L; Feltwell T; Hance Z; Harris B; Hauser H; Holroyd S; Jagels K; James KD; Lennard N; Line A; Mayes R; Moule S; Mungall K; Ormond D; Quail MA; Rabbinowitsch E; Rutherford K; Sanders M; Sharp S; Simmonds M; Stevens K; Whitehead S; Barrell BG; Spratt BG; Parkhill J. (29 Jun 2004). Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A. 101:9786-9791. DOI.
  • Martin IM; Ison CA; Aanensen DM; Fenton KA; Spratt BG. (15 Apr 2004). Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area. J Infect Dis. 189:1497-1505. DOI.
  • Brown JS; Gilliland SM; Spratt BG; Holden DW. (Mar 2004). A locus contained within a variable region of pneumococcal pathogenicity island 1 contributes to virulence in mice. Infect Immun. 72:1587-1593.
  • Feil EJ; Li BC; Aanensen DM; Hanage WP; Spratt BG. (Mar 2004). eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J Bacteriol. 186:1518-1530.
  • McGregor KF; Bilek N; Bennett A; Kalia A; Beall B; Carapetis JR; Currie BJ; Sriprakash KS; et alSpratt BG; Bessen DE. (15 Feb 2004). Group A streptococci from a remote community have novel multilocus genotypes but share emm types and housekeeping alleles with isolates from worldwide sources. J Infect Dis. 189:717-723. DOI.
  • Hanage WP; Auranen K; Syrjänen R; Herva E; Mäkelä PH; Kilpi T; Spratt BG. (Jan 2004). Ability of pneumococcal serotypes and clones to cause acute otitis media: implications for the prevention of otitis media by conjugate vaccines. Infect Immun. 72:76-81.
  • Spratt BG. (2004). Exploring the concept of clonality in bacteria. Methods Mol Biol. 266:323-352. DOI.
  • Reinert RR; Muckel S; Al-Lahham A; Spratt BG; Brueggemann AB; Hakenbeck R; Lütticken R. (Nov 2003). Characterization of German penicillin non-susceptible serotype 23F pneumococci using multilocus sequence typing. J Med Microbiol. 52:981-987.
  • Eriksson BK; Norgren M; McGregor K; Spratt BG; Normark BH. (1 Nov 2003). Group A streptococcal infections in Sweden: a comparative study of invasive and noninvasive infections and analysis of dominant T28 emm28 isolates. Clin Infect Dis. 37:1189-1193. DOI.
  • Brueggemann AB; Spratt BG. (Nov 2003). Geographic distribution and clonal diversity of Streptococcus pneumoniae serotype 1 isolates. J Clin Microbiol. 41:4966-4970.
  • Godoy D; Randle G; Simpson AJ; Aanensen DM; Pitt TL; Kinoshita R; Spratt BG. (Oct 2003). Multilocus sequence typing and evolutionary relationships among the causative agents of melioidosis and glanders, Burkholderia pseudomallei and Burkholdefia mallei (vol 41, pg 2068, 2003). J CLIN MICROBIOL. 41:4913-4913. DOI.
  • Jones N; Bohnsack JF; Takahashi S; Oliver KA; Chan MS; Kunst F; Glaser P; Rusniok C; et alCrook DW; Harding RM; Bisharat N; Spratt BG. (Jun 2003). Multilocus sequence typing system for group B streptococcus. J Clin Microbiol. 41:2530-2536.
  • Feil EJ; Cooper JE; Grundmann H; Robinson DA; Enright MC; Berendt T; Peacock SJ; Smith JM; et alMurphy M; Spratt BG; Moore CE; Day NP. (Jun 2003). How clonal is Staphylococcus aureus?. J Bacteriol. 185:3307-3316.
  • Spratt B. (17 May 2003). DU alarmists. NEW SCI. 178:24-24.
  • Brueggemann AB; Griffiths DT; Meats E; Peto T; Crook DW; Spratt BG. (1 May 2003). Clonal relationships between invasive and carriage Streptococcus pneumoniae and serotype- and clone-specific differences in invasive disease potential. J Infect Dis. 187:1424-1432. DOI.
  • Godoy D; Randle G; Simpson AJ; Aanensen DM; Pitt TL; Kinoshita R; Spratt BG. (May 2003). Multilocus sequence typing and evolutionary relationships among the causative agents of melioidosis and glanders, Burkholderia pseudomallei and Burkholderia mallei. J Clin Microbiol. 41:2068-2079.
  • Meats E; Feil EJ; Stringer S; Cody AJ; Goldstein R; Kroll JS; Popovic T; Spratt BG. (Apr 2003). Characterization of encapsulated and noncapsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J Clin Microbiol. 41:1623-1636.
  • Spratt BG. (7 Mar 2003). Microbiology. Stomachs out of Africa. Science. 299:1528-1529. DOI.
  • Sadowy E; Zhou J; Meats E; Gniadkowski M; Spratt BG; Hryniewicz W. (2003). Identification of multidrug-resistant Streptococcus pneumoniae strains isolated in Poland by multilocus sequence typing. Microb Drug Resist. 9:81-86. DOI.
  • Meats E; Brueggemann AB; Enright MC; Sleeman K; Griffiths DT; Crook DW; Spratt BG. (Jan 2003). Stability of serotypes during nasopharyngeal carriage of Streptococcus pneumoniae. J Clin Microbiol. 41:386-392.
  • Murray VS; Bailey MR; Spratt BG. (Dec 2002). Depleted uranium: a new battlefield hazard. Lancet. 360 Suppl:s31-s32.
  • Parry CM; Duong NM; Zhou J; Mai NT; Diep TS; Thinh LEQ; Wain J; Van Vinh Chau N; et alGriffiths D; Day NP; White NJ; Hien TT; Spratt BG; Farrar JJ. (Nov 2002). Emergence in Vietnam of Streptococcus pneumoniae resistant to multiple antimicrobial agents as a result of dissemination of the multiresistant Spain(23F)-1 clone. Antimicrob Agents Chemother. 46:3512-3517.
  • Spratt BG. (Jun 2002). Depleted uranium munitions-where are we now?. J Radiol Prot. 22:125-129.
  • Enright MC; Robinson DA; Randle G; Feil EJ; Grundmann H; Spratt BG. (28 May 2002). The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA). Proc Natl Acad Sci U S A. 99:7687-7692. DOI.
  • Kalia A; Spratt BG; Enright MC; Bessen DE. (Apr 2002). Influence of recombination and niche separation on the population genetic structure of the pathogen Streptococcus pyogenes. Infect Immun. 70:1971-1983.
  • Chan MS; Maiden MC; Spratt BG. (Nov 2001). Database-driven multi locus sequence typing (MLST) of bacterial pathogens. Bioinformatics. 17:1077-1083.
  • Spratt BG; Hanage WP; Feil EJ. (Oct 2001). The relative contributions of recombination and point mutation to the diversification of bacterial clones. Curr Opin Microbiol. 4:602-606.
  • Henriques Normark B; Kalin M; Ortqvist A; Akerlund T; Liljequist BO; Hedlund J; Svenson SB; Zhou J; et alSpratt BG; Normark S; Källenius G. (1 Oct 2001). Dynamics of penicillin-susceptible clones in invasive pneumococcal disease. J Infect Dis. 184:861-869. DOI.
  • Kalia A; Enright MC; Spratt BG; Bessen DE. (Aug 2001). Directional gene movement from human-pathogenic to commensal-like streptococci. Infect Immun. 69:4858-4869. DOI.
  • McGee L; McDougal L; Zhou J; Spratt BG; Tenover FC; George R; Hakenbeck R; Hryniewicz W; et alLefévre JC; Tomasz A; Klugman KP. (Jul 2001). Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. J Clin Microbiol. 39:2565-2571. DOI.
  • Enright MC; Spratt BG; Kalia A; Cross JH; Bessen DE. (Apr 2001). Multilocus sequence typing of Streptococcus pyogenes and the relationships between emm type and clone. Infect Immun. 69:2416-2427. DOI.
  • Feil EJ; Holmes EC; Bessen DE; Chan MS; Day NPJ; Enright MC; Goldstein R; Hood DW; et alKalia A; Moore CE; Zhou JJ; Spratt BG. (27 Mar 2001). Recombination within natural populations of pathogenic bacteria: Short-term empirical estimates and long-term phylogenetic consequences (vol 98, pg 182, 2001). P NATL ACAD SCI USA. 98:4276-4276.
  • Feil EJ; Holmes EC; Bessen DE; Chan MS; Day NP; Enright MC; Goldstein R; Hood DW; et alKalia A; Moore CE; Zhou J; Spratt BG. (2 Jan 2001). Recombination within natural populations of pathogenic bacteria: short-term empirical estimates and long-term phylogenetic consequences. Proc Natl Acad Sci U S A. 98:182-187. DOI.
  • Feil EJ; Spratt BG. (2001). Recombination and the population structures of bacterial pathogens. Annu Rev Microbiol. 55:561-590. DOI.
  • Spratt BG; Greenwood BM. (7 Oct 2000). Prevention of pneumococcal disease by vaccination: does serotype replacement matter?. Lancet. 356:1210-1211. DOI.
  • Feil EJ; Enright MC; Spratt BG. (Jul 2000). Estimating the relative contributions of mutation and recombination to clonal diversification: a comparison between Neisseria meningitidis and Streptococcus pneumoniae. Res Microbiol. 151:465-469.
  • Feil EJ; Smith JM; Enright MC; Spratt BG. (Apr 2000). Estimating recombinational parameters in Streptococcus pneumoniae from multilocus sequence typing data. Genetics. 154:1439-1450.
  • Parkhill J; Achtman M; James KD; Bentley SD; Churcher C; Klee SR; Morelli G; Basham D; et alBrown D; Chillingworth T; Davies RM; Davis P; Devlin K; Feltwell T; Hamlin N; Holroyd S; Jagels K; Leather S; Moule S; Mungall K; Quail MA; Rajandream MA; Rutherford KM; Simmonds M; Skelton J; Whitehead S; Spratt BG; Barrell BG. (30 Mar 2000). Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. Nature. 404:502-506. DOI.
  • Enright MC; Day NP; Davies CE; Peacock SJ; Spratt BG. (Mar 2000). Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. J Clin Microbiol. 38:1008-1015.
  • Zhou J; Enright MC; Spratt BG. (Mar 2000). Identification of the major Spanish clones of penicillin-resistant pneumococci via the Internet using multilocus sequence typing. J Clin Microbiol. 38:977-986.
  • Bowler LD; Hubank M; Spratt BG. (Dec 1999). Representational difference analysis of cDNA for the detection of differential gene expression in bacteria: development using a model of iron-regulated gene expression in Neisseria meningitidis. Microbiology. 145 ( Pt 12):3529-3537.
  • Enright MC; Spratt BG. (Dec 1999). Extensive variation in the ddl gene of penicillin-resistant Streptococcus pneumoniae results from a hitchhiking effect driven by the penicillin-binding protein 2b gene. Mol Biol Evol. 16:1687-1695.
  • Enright MC; Spratt BG. (Dec 1999). Multilocus sequence typing. Trends Microbiol. 7:482-487.
  • Feil EJ; Maiden MC; Achtman M; Spratt BG. (Nov 1999). The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis. Mol Biol Evol. 16:1496-1502.
  • Enright MC; Fenoll A; Griffiths D; Spratt BG. (Oct 1999). The three major Spanish clones of penicillin-resistant Streptococcus pneumoniae are the most common clones recovered in recent cases of meningitis in Spain. J Clin Microbiol. 37:3210-3216.
  • Maiden MC; Spratt BG. (21 Aug 1999). Meningococcal conjugate vaccines: new opportunities and new challenges. Lancet. 354:615-616.
  • Coffey TJ; Daniels M; Enright MC; Spratt BG. (Aug 1999). Serotype 14 variants of the Spanish penicillin-resistant serotype 9V clone of Streptococcus pneumoniae arose by large recombinational replacements of the cpsA-pbp1a region. MICROBIOL-UK. 145:2023-2031.
  • Smith NH; Holmes EC; Donovan GM; Carpenter GA; Spratt BG. (Jun 1999). Networks and groups within the genus Neisseria: analysis of argF, recA, rho, and 16S rRNA sequences from human Neisseria species. Mol Biol Evol. 16:773-783.
  • Spratt BG. (Jun 1999). Multilocus sequence typing: molecular typing of bacterial pathogens in an era of rapid DNA sequencing and the internet. Curr Opin Microbiol. 2:312-316. DOI.
  • Spratt BG; Maiden MC. (29 Apr 1999). Bacterial population genetics, evolution and epidemiology. Philos Trans R Soc Lond B Biol Sci. 354:701-710. DOI.
  • Morona JK; Miller DC; Coffey TJ; Vindurampulle CJ; Spratt BG; Morona R; Paton JC. (Apr 1999). Molecular and genetic characterization of the capsule biosynthesis locus of Streptococcus pneumoniae type 23F. MICROBIOL-UK. 145:781-789.
  • Shi ZY; Enright MC; Wilkinson P; Griffiths D; Spratt BG. (Dec 1998). Identification of three major clones of multiply antibiotic-resistant Streptococcus pneumoniae in Taiwanese hospitals by multilocus sequence typing. J Clin Microbiol. 36:3514-3519.
  • Enright MC; Spratt BG. (Nov 1998). A multilocus sequence typing scheme for Streptococcus pneumoniae: identification of clones associated with serious invasive disease. MICROBIOL-UK. 144:3049-3060.
  • Maiden MC; Bygraves JA; Feil E; Morelli G; Russell JE; Urwin R; Zhang Q; Zhou J; et alZurth K; Caugant DA; Feavers IM; Achtman M; Spratt BG. (17 Mar 1998). Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms. Proc Natl Acad Sci U S A. 95:3140-3145.
  • Veal WL; Yellen A; Balthazar JT; Pan W; Spratt BG; Shafer WM. (Mar 1998). Loss-of-function mutations in the mtr efflux system of Neisseria gonorrhoeae. Microbiology. 144 ( Pt 3):621-627.
  • Coffey TJ; Enright MC; Daniels M; Morona JK; Morona R; Hryniewicz W; Paton JC; Spratt BG. (Jan 1998). Recombinational exchanges at the capsular polysaccharide biosynthetic locus lead to frequent serotype changes among natural isolates of Streptococcus pneumoniae. Mol Microbiol. 27:73-83.
  • Crook DW; Spratt BG. (1998). Multiple antibiotic resistance in Streptococcus pneumoniae. Br Med Bull. 54:595-610.
  • Coffey TJ; Enright MC; Daniels M; Wilkinson P; Berrón S; Fenoll A; Spratt BG. (1998). Serotype 19A variants of the Spanish serotype 23F multiresistant clone of Streptococcus pneumoniae. Microb Drug Resist. 4:51-55.
  • Spratt BG. (1998). Resurgent emergent infectious diseases - Preface. BRIT MED BULL. 54:521-521.
  • Gutjahr TS; O'Rourke M; Ison CA; Spratt BG. (Feb 1997). Arginine-, hypoxanthine-, uracil-requiring isolates of Neisseria gonorrhoeae are a clonal lineage with a non-clonal population. Microbiology. 143 ( Pt 2):633-640.
  • Zhou J; Bowler LD; Spratt BG. (Feb 1997). Interspecies recombination, and phylogenetic distortions, within the glutamine synthetase and shikimate dehydrogenase genes of Neisseria meningitidis and commensal Neisseria species. Mol Microbiol. 23:799-812.

Books

  • Spratt BG; Bailey MR; Beral V; Clayton B; Goodhead DT; Darby SC; Hendry J; MArsh C; et alMurray V; Smith B; Stoneham M. Report of the royal society working group on the health hazards of depleted uranium munitions, part II - chemical toxicity and environmental effects. (Jun 2005). Author weblink.

Chapters in books

  • Spratt BG. Health Hazards of Depleted Uranium Munitions: Estimatesof Exposures and Risks in the Gulf War, the Balkans, and Iraq. In Depleted Uranium: Properties, Uses, and Health Consequences. 121-141. Miller AC (ed). CRC Press, USA (2006).
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