Dr Claudia Monaco

Publications


Journals

  • Terrando N; Eriksson LI; Ryu JK; Yang T; Monaco C; Feldmann M; Fagerlund MJ; Charo IF; et alAkassoglou K; Maze M. (1 Dec 2011). Resolving postoperative neuroinflammation and cognitive decline. ANNALS OF NEUROLOGY. 70:986-995. DOI.
  • Seneviratne AN; Sivagurunathan B; Monaco C. (18 Jan 2012). Toll-like receptors and macrophage activation in atherosclerosis. Clin Chim Acta. 413:3-14. DOI.
  • Shalhoub J; Monaco C; Owen DR; Gauthier T; Thapar A; Leen EL; Davies AH. (Dec 2011). Late-phase contrast-enhanced ultrasound reflects biological features of instability in human carotid atherosclerosis. Stroke. 42:3634-3636. DOI.
  • Full LE; Monaco C. (1 Jan 2011). Targeting Inflammation as a Therapeutic Strategy in Accelerated Atherosclerosis in Rheumatoid Arthritis. CARDIOVASCULAR THERAPEUTICS. 29:231-242. DOI.
  • Kiriakidis S; Andreakos E; Monaco C; Foxwell B; Feldmann M; Paleolog E. (1 Apr 2003). REGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) IN RHEUMATOID ARTHRITIS BY THE TRANSCRIPTION FACTOR NF kappa B. RHEUMATOLOGY. 42:42-43. Author weblink.
  • Monaco C; Andreakos E; Kiriakidis S; Feldmann M; Paleolog E. (1 Apr 2002). REQUIREMENT FOR NF kappa B AND IKK-2 IN TISSUE FACTOR EXPRESSION BY CELLS RELEVANT TO THE PATHOGENESIS OF ATHEROSCLEROSIS AND RHEUMATOID ARTHRITIS. RHEUMATOLOGY. 41:32-32. Author weblink.
  • Kiriakidis S; Andreakos E; Monaco C; Foxwell B; Feldmann M; Paleolog E. (1 Apr 2002). VEGF EXPRESSION IN HUMAN MACROPHAGES IS NF kappa B-DEPENDENT: STUDIES USING ADENOVIRUSES EXPRESSING A KINASE DEFECTIVE FORM OF IKK2 or I kappa B alpha THE NATURAL NF kappa B INHIBITOR. RHEUMATOLOGY. 41:66-66. Author weblink.
  • Andreakos E; Kiriakidis S; Monaco C; Smith C; Foxwell B; Paleolog E; Feldmann M. (1 Apr 2002). SELECTIVE USAGE OF IKK2 FOR NF-kappa B ACTIVATION AND PRO-INFLAMMATORY GENE EXPRESSION: STUDIES IN HUMAN PRIMARY CELLS AND RHEUMATOID SYNOVIAL MEMBRANE CELL CULTURES. RHEUMATOLOGY. 41:65-65. Author weblink.
  • Monaco C; Terrando N; Midwood KS. (Apr 2011). Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritis. Arthritis Care Res (Hoboken). 63:500-511. DOI.
  • Cole JE; Mitra AT; Monaco C. (Nov 2010). Treating atherosclerosis: the potential of Toll-like receptors as therapeutic targets. Expert Rev Cardiovasc Ther. 8:1619-1635. DOI.
  • Monaco C. (1 Jan 2011). Innate immunity meets arteriogenesis: The versatility of toll-like receptors. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 50:9-12. DOI.
  • Terrando N; Fidalgo AR; Vizcaychipi M; Cibelli M; Ma D; Monaco C; Feldmann M; Maze M. (2010). The impact of IL-1 modulation on the development of LPS-induced cognitive dysfunction. Crit Care. 14. DOI.
  • Cole JE; Georgiou E; Monaco C. (2010). The expression and functions of toll-like receptors in atherosclerosis. Mediators Inflamm. 2010:393946. DOI.
  • Cibelli M; Fidalgo AR; Terrando N; Ma D; Monaco C; Feldmann M; Takata M; Lever I; et alNanchahal J; Fanselow M; Maze M. (2010). Role of Interleukin-1β in Postoperative Cognitive Dysfunction. Ann Neurol. 68:360-368. DOI.
  • Terrando N; Fidalgo AR; Vizcaychipi MP; Cibelli M; Ma D; Monaco C; Feldmann M; Maze M. (May 2010). The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction. Critical Care. Publisher weblink.
  • Gorman CL; Monaco C; Ammiratti E; Vermi AC; Marelli-Berg FM; Cope AP. (2010). Tracking antigen-experienced effector T cells in vitro and in vivo. Methods Mol Biol. 616:253-267. DOI.
  • Monaco C; Gregan SM; Navin TJ; Foxwell BMJ; Davies AH; Feldmann M. (15 Dec 2009). Toll-Like Receptor-2 Mediates Inflammation and Matrix Degradation in Human Atherosclerosis. CIRCULATION. 120:2462-2469. Author weblink DOI.
  • Full LE; Ruisanchez C; Monaco C. (2009). The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus. Arthritis Res Ther. 11:217. DOI.
  • Ammirati E; Vermi A-C; Cianflone D; Banfi M; Foglieni C; Godino C; Airoldi F; Ferri LA; et alGorman CL; Manfredi AA; Maseri A; Cope AP; Monaco C. (1 Dec 2008). Expansion of T-Cell Receptor zeta(dim) Effector T Cells in Acute Coronary Syndromes. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 28:2305-2311. Author weblink DOI.
  • Lundberg AM; Drexler SK; Monaco C; Williams LM; Sacre SM; Feldmann M; Foxwell BM. (1 Nov 2007). Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems. Blood. 110:3245-3252. DOI.
  • Zhang Z; Gorman CL; Vermi AC; Monaco C; Foey A; Owen S; Amjadi P; Vallance A; et alMcClinton C; Marelli-Berg F; Isomäki P; Russell A; Dazzi F; Vyse TJ; Brennan FM; Cope AP. (15 May 2007). TCRzetadim lymphocytes define populations of circulating effector cells that migrate to inflamed tissues. Blood. 109:4328-4335. DOI.
  • Monaco C; Andreakos E; Feldmann M; Paleolog E. (1 Feb 2001). Inhibition of tissue factor induction by blockade of the nuclear factor-kappa B pathway in human macrophages and endothelial cells using adenoviral gene transfer: Nuclear factor-kappa B as a potential therapeutic target for plaque stabilization. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 37:289A-289A. Author weblink.
  • Kiriakidis S; Andreakos E; Monaco C; Foxwell B; Feldmann M; Paleolog E. (1 Sep 2002). Inhibition of VEGF in human macrophages and rheumatoid synovial cells by blockade of the NF kappa B pathway using adenoviral gene transfer. JOURNAL OF MOLECULAR MEDICINE-JMM. 80:B3-B3. Author weblink.
  • Monaco C; Mathur A; Martin JF. (Mar 2005). What causes acute coronary syndromes? Applying Koch's postulates. Atherosclerosis. 179:1-15. DOI.
  • Monaco C; Rossi E; Milazzo D; Citterio F; Ginnetti F; D'Onofrio G; Cianflone D; Crea F; et alBiasucci LM; Maseri A. (18 Jan 2005). Persistent systemic inflammation in unstable angina is largely unrelated to the atherothrombotic burden. J Am Coll Cardiol. 45:238-243. DOI.
  • Monaco C; Andreakos E; Kiriakidis S; Mauri C; Bicknell C; Foxwell B; Cheshire N; Paleolog E; et alFeldmann M. (13 Apr 2004). Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis. Proc Natl Acad Sci U S A. 101:5634-5639. DOI.
  • Andreakos E; Sacre SM; Smith C; Lundberg A; Kiriakidis S; Stonehouse T; Monaco C; Feldmann M; et alFoxwell BM. (15 Mar 2004). Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. Blood. 103:2229-2237. DOI.
  • Monaco C; Paleolog E. (1 Mar 2004). Nuclear factor kappaB: a potential therapeutic target in atherosclerosis and thrombosis. Cardiovasc Res. 61:671-682. DOI.
  • Monaco C; Andreakos E; Kiriakidis S; Feldmann M; Paleolog E. (Mar 2004). T-cell-mediated signalling in immune, inflammatory and angiogenic processes: the cascade of events leading to inflammatory diseases. Curr Drug Targets Inflamm Allergy. 3:35-42.
  • Andreakos E; Smith C; Kiriakidis S; Monaco C; de Martin R; Brennan FM; Paleolog E; Feldmann M; et alFoxwell BM. (Jul 2003). Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy. Arthritis Rheum. 48:1901-1912. DOI.
  • Kiriakidis S; Andreakos E; Monaco C; Foxwell B; Feldmann M; Paleolog E. (15 Feb 2003). VEGF expression in human macrophages is NF-kappaB-dependent: studies using adenoviruses expressing the endogenous NF-kappaB inhibitor IkappaBalpha and a kinase-defective form of the IkappaB kinase 2. J Cell Sci. 116:665-674.
  • Andreakos E; Smith C; Monaco C; Brennan FM; Foxwell BM; Feldmann M. (1 Feb 2003). Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction. Blood. 101:983-991. DOI.
  • Feldmann M; Andreakos E; Smith C; Bondeson J; Yoshimura S; Kiriakidis S; Monaco C; Gasparini C; et alSacre S; Lundberg A; Paleolog E; Horwood NJ; Brennan FM; Foxwell BM. (Nov 2002). Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?. Ann Rheum Dis. 61 Suppl 2:ii13-ii18.
  • Crea F; Monaco C; Lanza GA; Maggi E; Ginnetti F; Cianflone D; Niccoli G; Cook T; et alBellomo G; Kjekshus J. (Oct 2002). Inflammatory predictors of mortality in the Scandinavian Simvastatin Survival Study. Clin Cardiol. 25:461-466.
  • Monaco C; Andreakos E; Young S; Feldmann M; Paleolog E. (Apr 2002). T cell-mediated signaling to vascular endothelium: induction of cytokines, chemokines, and tissue factor. J Leukoc Biol. 71:659-668.
  • Rossi E; Biasucci LM; Citterio F; Pelliccioni S; Monaco C; Ginnetti F; Angiolillo DJ; Grieco G; et alLiuzzo G; Maseri A. (19 Feb 2002). Risk of myocardial infarction and angina in patients with severe peripheral vascular disease: predictive role of C-reactive protein. Circulation. 105:800-803.
  • Monaco C; Crea F; Niccoli G; Summaria F; Cianflone D; Bordone R; Bellomo G; Maseri A. (Sep 2001). Autoantibodies against oxidized low density lipoproteins in patients with stable angina, unstable angina or peripheral vascular disease; pathophysiological implications. Eur Heart J. 22:1572-1577. DOI.
  • Monaco C; Cianflone D; Summaria F; Maseri A; Crea F. (Jun 1998). Cost-effective pharmacological prevention of acute coronary syndromes. Pharmacol Res. 37:469-475. DOI.
  • Crea F; Biasucci LM; Buffon A; Liuzzo G; Monaco C; Caligiuri G; Kol A; Sperti G; et alCianflone D; Maseri A. (4 Sep 1997). Role of inflammation in the pathogenesis of unstable coronary artery disease. Am J Cardiol. 80:10E-16E.
  • Biasucci LM; Vitelli A; Liuzzo G; Altamura S; Caligiuri G; Monaco C; Rebuzzi AG; Ciliberto G; et alMaseri A. (1 Sep 1996). Elevated levels of interleukin-6 in unstable angina. Circulation. 94:874-877.
  • Biasucci LM; D'Onofrio G; Liuzzo G; Zini G; Monaco C; Caligiuri G; Tommasi M; Rebuzzi AG; et alMaseri A. (1 Mar 1996). Intracellular neutrophil myeloperoxidase is reduced in unstable angina and acute myocardial infarction, but its reduction is not related to ischemia. J Am Coll Cardiol. 27:611-616.
  • Biasucci LM; Liuzzo G; Caligiuri G; van de Greef W; Quaranta G; Monaco C; Rebuzzi AG; Kluft C; et alMaseri A. (1 Jan 1996). Episodic activation of the coagulation system in unstable angina does not elicit an acute phase reaction. Am J Cardiol. 77:85-87.

Conferences

  • Falck-Hansen MA; Goddard ME; Cole JE; Astola N; Cross AC; Krams R; Monaco C. Expression of the inhibitory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis. Immunology, Liverpool, UK (24 Nov 2011). Publisher weblink.
  • Falck-Hansen M; Goddard ME; Cole JE; Astola N; Cross AJ; Krams R; Monaco C. Expression of the regulatory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis. Annual Congress of the British-Society-for-Immunology, 5 Dec 2011 - 8 Dec 2011. 135:109-109. WILEY-BLACKWELL (1 Dec 2011). Author weblink.
  • Shalhoub J; Cross A; Allin DM; Franklin IJ; Monaco C; Davies AH. Intra-plaque production of M1-type cytokines and matrix metalloproteinases differentiate stable from unstable carotid atherosclerosis. 45th Annual Scientific Meeting of the Vascular-Society-of-Great-Britain-and-Ireland, 24 Nov 2010 - 26 Nov 2010. 98:3-3. WILEY-BLACKWELL (1 Jan 2011).
  • Shalhoub J; Cross A; Allin D; Davies AH; Monaco C. Intra-plaque production of M1-type cytokines and matrix metalloproteinases differentiate stable from unstable carotid atherosclerosis. 213:E17-E18. ELSEVIER IRELAND LTD (1 Nov 2010). Author weblink DOI.
  • Montecucco F; Steffens S; Burger F; Pelli G; Monaco C; Mach F. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes. Pennington Scientific Symposium on Neuro-Immune Signaling and Inflammation, 2 Dec 2007 - 5 Dec 2007. 84:1109-1119. FEDERATION AMER SOC EXP BIOL (1 Oct 2008). Author weblink DOI.
  • Monaco C; Paleolog E; Cheshire N; Feldmann M. Direct analysis of gene expression and regulation in human atherosclerotic tissue: Nuclear factor kappa B regulates production of cytokines and tissue factor. American-Heart-Association Abstracts From Scientific Sessions. 106:259-259. (5 Nov 2002).
  • Kiriakidis S; Monaco C; Andreakos E; Foxwell B; Feldmann M; Paleolog E. VEGF expression in human macrophages is NFkB-dependent: studies using adenoviral gene transfer. Congress of the European-Society-of-Cardiology. 23:382-382. (Aug 2002).
  • Raisakis K; Monaco C; Stamatelopoulos K; Desforges L; Liodakis E; Nihoyannopoulos P. Cytokines for myocardial ischaemia: a echocardiographic study. World Congress of Cardiology. 27:561-561. (Aug 2006).
  • Finch J; Navin T; Gregan S; Foxwell B; Haskard D; Monaco C; Hornick P. NF-kappa B inhibition by blockade of IKK-2 and MYD88 in vein graft smooth muscle cells reduces the expression of key mediators of intimal hyperplasia. Annual Scientific Conference of the British-Cardiovascular-Society. 93:A24-A25. (Jun 2007).
  • Persson L; Navin T; Gregan S; Davies AH; Feldmann M; Monaco C. Inhibition of tissue factor signalling reduces production of pro-inflammatory cytokines in atheroma smooth muscle cells. 14th Meeting of the International-Society-of-Atherosclerosis, 18 Jun 2006 - 22 Jun 2006. 7:92-93. ELSEVIER IRELAND LTD (1 Jun 2006). Author weblink DOI.
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