Publications

Journals

• Martinez-Sanchez A; Dudek KA; Murphy CL. (6 Jan 2012). Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145). J Biol Chem. 287:916-924. DOI.
• Murphy CL. (Sep 2011). What makes the permanent articular cartilage permanent?. Arthritis Rheum. 63:2564-2566. DOI.
• Murphy CL. (Jul 2010). HIF-2alpha - a mediator of osteoarthritis?. Cell Research. Publisher weblink Author weblink DOI.
• Dudek K; Lafont J; Martinez-Sanchez A; Murphy CL. (Jun 2010). Type II Collagen Expression is Regulated by Tissue-specific miR-675 in Human Articular Chondrocytes. The Journal of Biological Chemistry. Epub ahead of print. Publisher weblink DOI.
• Thoms BL; Murphy CL. (Apr 2010). Inhibition of hypoxia-inducible factor-targeting prolyl hydroxylase domain-containing protein 2 (PHD2) enhances matrix synthesis by human chondrocytes. The Journal of Biological Chemistry. Epub ahead of print. Author weblink DOI.
• Vaghjiani RJ; Talma S; Murphy CL. (1 Aug 2009). Six-Transmembrane Epithelial Antigen of the Prostate (STEAP1 and STEAP2)-Differentially Expressed by Murine and Human Mesenchymal Stem Cells. TISSUE ENGINEERING PART A. 15:2073-2083. Author weblink DOI.
• Jones SW; Watkins G; Le Good N; Roberts S; Murphy CL; Brockbank SMV; Needham MRC; Read SJ; et alNewham P. (1 Apr 2009). The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13. OSTEOARTHRITIS AND CARTILAGE. 17:464-472. Author weblink DOI.
• Murphy CL; Thoms BL; Vaghjiani RJ; Lafont JE. (2009). Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair. Arthritis Res Ther. 11:213. DOI.
• Lafont JE; Talma S; Hopfgarten C; Murphy CL. (2008). Hypoxia promotes the differentiated human articular chondrocyte phenotype through SOX9-dependent and independent pathways. The Journal of Biological Chemistry. 283:4778-4786. Publisher weblink Author weblink DOI.
• Lafont JE; Talma S; Murphy CL. (Oct 2007). Hypoxia-Inducible Factor 2alpha is Essential for Hypoxic Induction of the Human Articular Chondrocyte Phenotype. Arthirtis and Rheumatism. 56:3297-3306. Publisher weblink DOI.
• Rogers BA; Murphy CL; Cannon SR; Briggs TWR. (1 Dec 2006). Topographical variation in glycosaminoglycan content in human articular cartilage. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME. 88B:1670-1674. Author weblink DOI.
• Murphy CL. (2006). Internal standards in differentiating embryonic stem cells in vitro. Methods Mol Biol. 329:101-112. DOI.
• Murphy CL; Polak JM. (Jun 2004). Control of human articular chondrocyte differentiation by reduced oxygen tension. J Cell Physiol. 199:451-459. DOI.
• Tanaka H; Murphy CL; Murphy C; Kimura M; Kawai S; Polak JM. (15 Oct 2004). Chondrogenic differentiation of murine embryonic stem cells: effects of culture conditions and dexamethasone. J Cell Biochem. 93:454-462. DOI.
• Murphy CL; Sambanis A. (Dec 2001). Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes. Tissue Eng. 7:791-803. DOI.
• Murphy CL; Sambanis A. (Oct 2001). Effect of oxygen tension on chondrocyte extracellular matrix accumulation. Connect Tissue Res. 42:87-96.
• Murphy CL; Polak JM. (Aug 2002). Differentiating embryonic stem cells: GAPDH, but neither HPRT nor beta-tubulin is suitable as an internal standard for measuring RNA levels. Tissue Eng. 8:551-559. DOI.
• Murphy CL; Lever MJ. (Mar 2002). A ratiometric method of autofluorescence correction used for the quantification of Evans blue dye fluorescence in rabbit arterial tissues. Exp Physiol. 87:163-170.
• Murphy CL; Lever MJ. (Mar 2002). Sulphorhodamine-B-labelled albumin uptake around the ostium of the renal artery in rabbits: changes with age. J Vasc Res. 39:104-113.

Chapters in books

• Murphy, CL. Internal standards in differentiating embryonic stem cells in vitro. In Methods in Molecular Biology. 329:101-112. Humana Press, United States (19 Jul 2006). Author weblink.