Dr Carsten B Schmidt-Weber

Publications


Journals

  • Eyerich S; Eyerich K; Pennino D; Carbone T; Nasorri F; Pallotta S; Cianfarani F; Odorisio T; et alTraidl-Hoffmann C; Behrendt H; Durham SR; Schmidt-Weber CB; Cavani A. (1 Dec 2009). Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling. JOURNAL OF CLINICAL INVESTIGATION. 119:3573-3585. Author weblink DOI.
  • Provoost S; Maes T; van Durme YM; Gevaert P; Bachert C; Schmidt-Weber CB; Brusselle GG; Joos GF; et alTournoy KG. (1 Oct 2009). Decreased FOXP3 protein expression in patients with asthma. ALLERGY. 64:1539-1546. Author weblink DOI.
  • Burgler S; Ouaked N; Bassin C; Basinski TM; Mantel P-Y; Siegmund K; Meyer N; Akdis CA; et alSchmidt-Weber CB. (1 Mar 2009). Differentiation and functional analysis of human T(H)17 cells. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 123:588-595. Author weblink DOI.
  • Broere F; du Pré MF; van Berkel LA; Garssen J; Schmidt-Weber CB; Lambrecht BN; Hendriks RW; Nieuwenhuis EE; et alKraal G; Samsom JN. (May 2009). Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4. Mucosal Immunol. 2:254-264. DOI.
  • Siegmund K; Rückert B; Ouaked N; Bürgler S; Speiser A; Akdis CA; Schmidt-Weber CB. (15 Feb 2009). Unique phenotype of human tonsillar and in vitro-induced FOXP3+CD8+ T cells. J Immunol. 182:2124-2130. DOI.
  • Ouaked N; Mantel PY; Bassin C; Burgler S; Siegmund K; Akdis CA; Schmidt-Weber CB. (15 Jan 2009). Regulation of the foxp3 gene by the Th1 cytokines: the role of IL-27-induced STAT1. J Immunol. 182:1041-1049.
  • Schmidt-Weber CB. (2008). Th17 and treg cells innovate the TH1/TH2 concept and allergy research. Chem Immunol Allergy. 94:1-7. DOI.
  • Mantel P-Y; Kuipers H; Boyman O; Rhyner C; Ouaked N; Ruckert B; Karagiannidis C; Lambrecht BN; et alHendriks RW; Crameri R; Akdis CA; Blaser K; Schmidt-Weber CB. (1 Dec 2007). GATA3-driven Th2 responses inhibit TGF-beta 1-induced FOXP3 expression and the formation of regulatory T cells. PLOS BIOLOGY. 5:2847-2861. Author weblink DOI.
  • Saruta M; Yu QT; Fleshner PR; Mantel PY; Schmidt-Weber CB; Banham AH; Papadakis KA. (Dec 2007). Characterization of FOXP3+CD4+ regulatory T cells in Crohn's disease. Clin Immunol. 125:281-290. DOI.
  • Schmidt-Weber CB; Alexander SI; Henault LE; James L; Lichtman AH. (1 Jan 1999). IL-4 enhances IL-10 gene expression in murine Th2 cells in the absence of TCR engagement. JOURNAL OF IMMUNOLOGY. 162:238-244. Author weblink.
  • Schmidt-Weber CB; Pohlers D; Siegling A; Schadlich H; Buchner E; Volk HD; Palombo-Kinne E; Emmrich F; et alKinne RW. (10 Jul 1999). Cytokine gene activation in synovial membrane, regional lymph nodes, and spleen during the course of rat adjuvant arthritis. CELLULAR IMMUNOLOGY. 195:53-65. Author weblink DOI.
  • Schmidt-Weber CB; Wohlfahrt JG; Blaser K. (1 Sep 2001). DNA arrays in allergy and immunology. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 126:1-10. Author weblink DOI.
  • Schmidt-Weber CB; Wohlfahrt JG; Akdis CA; Blaser K. (1 Apr 2002). The phosphatidylinositol phosphatase PTEN is under control of costimulation and regulates proliferation in human T cells. EUROPEAN JOURNAL OF IMMUNOLOGY. 32:1196-1204. Author weblink DOI.
  • Pohlers D; Schmidt-Weber CB; Franch A; Kuhlmann J; Brauer R; Emmrich F; Kinne RW. (1 Jan 2002). Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-kappa B binding activity and TNF-alpha secretion of T cells. ARTHRITIS RESEARCH. 4:184-U9. Author weblink DOI.
  • Wohlfahrt JG; Kunzmann S; Menz G; Kneist W; Akdis CA; Blaser K; Schmidt-Weber CB. (1 Aug 2003). T cell phenotype in allergic asthma and atopic dermatitis. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 131:272-282. Author weblink DOI.
  • Akdis CA; Kussebi F; Pulendran B; Akdis M; Lauener RP; Schmidt-Weber CB; Klunker S; Isitmangil G; et alHansjee N; Wynn TA; Dillon S; Erb P; Baschang G; Blaser K; Alkan SS. (1 Oct 2003). Inhibition of T helper 2-type responses, IgE production and eosinophilia by synthetic lipopeptides. EUROPEAN JOURNAL OF IMMUNOLOGY. 33:2717-2726. Author weblink DOI.
  • Tiemessen MM; Kunzmann S; Schmidt-Weber CB; Garssen J; Bruijnzeel-Koomen CAFM; Knol EF; Van Hoffen E. (1 Dec 2003). Transforming growth factor-beta inhibits human antigen-specific CD4(+) T cell proliferation without modulating the cytokine response. INTERNATIONAL IMMUNOLOGY. 15:1495-1504. Author weblink DOI.
  • Wohlfahrt JG; Karagiannidis C; Kunzmann S; Epstein MM; Kempf W; Blaser K; Schmidt-Weber CB. (15 Jan 2004). Ephrin-A1 suppresses Th2 cell activation and provides a regulatory link to lung epithelial cells. JOURNAL OF IMMUNOLOGY. 172:843-850. Author weblink.
  • Akdis M; Verhagen J; Taylor A; Karamloo F; Karagiannidis C; Crameri R; Thunberg S; Deniz G; et alValenta R; Fiebig H; Kegel C; Disch R; Schmidt-Weber CB; Blaser K; Akdis CA. (7 Jun 2004). Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. JOURNAL OF EXPERIMENTAL MEDICINE. 199:1567-1575. Author weblink DOI.
  • Karagiannidis C; Ruckert B; Hense G; Willer G; Menz G; Blaser K; Schmidt-Weber CB. (1 Feb 2005). Distinct leucocyte redistribution after glucocorticoid treatment among difficult-to-treat asthmatic patients. SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 61:187-196. Author weblink DOI.
  • Schmidt-Weber CB. (1 Jun 2005). The role of TGF-beta in immune regulation and allergy. ALLERGOLOGIE. 28:238-242. Author weblink.
  • Schmidt-Weber CB; Blaser K. (1 Dec 2005). New insights into the mechanisms of allergen-specific immunotherapy. CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 5:525-530. Author weblink DOI.
  • Karagiannidis C; Hense G; Martin C; Epstein M; Ruckert B; Mantel PY; Menz G; Uhlig S; et alBlaser K; Schmidt-Weber CB. (1 Jan 2006). Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 117:111-118. Author weblink DOI.
  • Schmidt-Weber CB; Akdis M; Akdis CA. (1 Aug 2007). T(H)17 cells in the big picture of immunology. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 120:247-254. Author weblink DOI.
  • Kinne RW; Schmidt-Weber CB; Hoppe R; Buchner E; Palombo-Kinne E; Nürnberg E; Emmrich F. (Dec 1995). Long-term amelioration of rat adjuvant arthritis following systemic elimination of macrophages by clodronate-containing liposomes. Arthritis Rheum. 38:1777-1790.
  • Schmidt-Weber CB; Rittig M; Buchner E; Hauser I; Schmidt I; Palombo-Kinne E; Emmrich F; Kinne RW. (Aug 1996). Apoptotic cell death in activated monocytes following incorporation of clodronate-liposomes. J Leukoc Biol. 60:230-244.
  • Liu L; Buchner E; Beitze D; Schmidt-Weber CB; Kaever V; Emmrich F; Kinne RW. (Oct 1996). Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine. Int J Immunopharmacol. 18:529-543.
  • Schmidt-Weber CB; Rao A; Lichtman AH. (Aug 2000). Integration of TCR and IL-4 signals through STAT6 and the regulation of IL-4 gene expression. Mol Immunol. 37:767-774.
  • Schmidt-Weber CB; Kunzmann S; Blaser K. (May 2002). TGF-beta-mediated control of allergen-specific T-cell responses. Curr Allergy Asthma Rep. 2:259-262.
  • Pohlers D; Schmidt-Weber CB; Franch A; Kuhlmann J; Bräuer R; Emmrich F; Kinne RW. (2002). Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-kappaB binding activity and TNF-alpha secretion of T cells. Arthritis Res. 4:184-189.
  • Schmidt-Weber CB; Blaser K. (Sep 2002). T-cell tolerance in allergic response. Allergy. 57:762-768.
  • Kunzmann S; Wohlfahrt JG; Itoh S; Asao H; Komada M; Akdis CA; Blaser K; Schmidt-Weber CB. (Feb 2003). SARA and Hgs attenuate susceptibility to TGF-beta1-mediated T cell suppression. FASEB J. 17:194-202. DOI.
  • Kunzmann S; Mantel PY; Wohlfahrt JG; Akdis M; Blaser K; Schmidt-Weber CB. (Jun 2003). Histamine enhances TGF-beta1-mediated suppression of Th2 responses. FASEB J. 17:1089-1095. DOI.
  • Schmidt-Weber CB; Blaser K. (Dec 2004). Regulation and role of transforming growth factor-beta in immune tolerance induction and inflammation. Curr Opin Immunol. 16:709-716. DOI.
  • Karagiannidis C; Akdis M; Holopainen P; Woolley NJ; Hense G; Rückert B; Mantel PY; Menz G; et alAkdis CA; Blaser K; Schmidt-Weber CB. (Dec 2004). Glucocorticoids upregulate FOXP3 expression and regulatory T cells in asthma. J Allergy Clin Immunol. 114:1425-1433. DOI.
  • Pohlers D; Siegling A; Buchner E; Schmidt-Weber CB; Palombo-Kinne E; Emmrich F; Bräuer R; Kinne RW. (2005). Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis. Arthritis Res Ther. 7:R445-R457. DOI.
  • Schmidt-Weber CB; Letarte M; Kunzmann S; Rückert B; Bernabéu C; Blaser K. (Jul 2005). TGF-{beta} signaling of human T cells is modulated by the ancillary TGF-{beta} receptor endoglin. Int Immunol. 17:921-930. DOI.
  • Schmidt-Weber CB; Blaser K. (Sep 2005). The role of the FOXP3 transcription factor in the immune regulation of allergic asthma. Curr Allergy Asthma Rep. 5:356-361.
  • Schmidt-Weber CB. (2006). Gene expression profiling in allergy and asthma. Chem Immunol Allergy. 91:188-194. DOI.
  • Mantel PY; Ouaked N; Rückert B; Karagiannidis C; Welz R; Blaser K; Schmidt-Weber CB. (15 Mar 2006). Molecular mechanisms underlying FOXP3 induction in human T cells. J Immunol. 176:3593-3602.
  • Schmidt-Weber CB; Blaser K. (Jan 2006). Immunological mechanisms of specific allergen immunotherapy. Inflamm Allergy Drug Targets. 5:15-21.
  • Karagiannidis C; Hense G; Rueckert B; Mantel PY; Ichters B; Blaser K; Menz G; Schmidt-Weber CB. (Apr 2006). High-altitude climate therapy reduces local airway inflammation and modulates lymphocyte activation. Scand J Immunol. 63:304-310. DOI.
  • Schmidt-Weber CB; Blaser K. (May 2006). The role of TGF-beta in allergic inflammation. Immunol Allergy Clin North Am. 26:233-vii. DOI.

Conferences

  • Scadding GW; Shamji MH; Jacobson MR; Lee DI; Kimber I; Schmidt-Weber CB; Nouri-Aria K; Durham SR. Local mucosal and systemic regulatory effects of grass pollen sublingual immunotherapy. Annual Conference of the British-Society-for-Allergy-and-Clinical-Immunology, 29 Jun 2009 - 1 Jul 2009. 39:1938-1938. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2009). Author weblink.
  • Kinne RW; Pohlers D; Siegling A; Buchner E; Schmidt-Weber CB; Palombo-Kinne E; Emmrich F; Braeuer R. Cytokine expression was assessed during antigen-induced arthritis in the synovial membrane, inguinal lymph node, and spleen using competitive RT-PCR and sandwich ELISA. 25th European Workshop for Rheumatology Research, 24 Feb 2005 - 27 Feb 2005. 7:S46-S46. BIOMED CENTRAL LTD (1 Feb 2005). Author weblink DOI.
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National Hearth & Lung Institute

Allergy and Clinical Immunology section 

Center of Allergy and Environment