Professor Desmond G Johnston

Publications


Journals

  • Patel DC; Albrecht C; Pavitt D; Paul V; Pourreyron C; Newman SP; Godsland IF; Valabhji J; et alJohnston DG. (2011). Type 2 diabetes is associated with reduced ATP-binding cassette transporter A1 gene expression, protein and function. PLoS One. 6:e22142. DOI.
  • Forbes S; Taylor-Robinson SD; Patel N; Allan P; Walker BR; Johnston DG. (Mar 2011). Increased prevalence of non-alcoholic fatty liver disease in European women with a history of gestational diabetes. Diabetologia. 54:641-647. DOI.
  • Godsland IF; North BV; Johnston DG. (May 2011). Simple indices of inflammation as predictors of death from cancer or cardiovascular disease in a prospective cohort after two decades of follow-up. QJM. 104:387-394. DOI.
  • Yee MS; Pavitt DV; Dhanjil S; Godsland IF; Richmond W; Johnston DG. (Dec 2010). The effects of rosiglitazone on atherosclerotic progression in patients with Type 2 diabetes at high cardiovascular risk. Diabet Med. 27:1392-1400. DOI.
  • Mehta SR; Godsland IF; Bell JD; Thomas EL; McCarthy J; Durighel G; Fitzpatrick J; Taylor-Robinson SD; et alJohnston DG. (1 May 2008). INTRA-HEPATIC INSULIN EXPOSURE IS INCREASED IN SUBJECTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD). ATHEROSCLEROSIS SUPPLEMENTS. 9:121-121. DOI.
  • Mehta SR; Thomas EL; Patel N; Crofton ME; McCarthy J; Eliahoo J; Morin SX; Fitzpatrick J; et alDurighel G; Goldstone AP; Johnston DG; Bell JD; Taylor-Robinson SD. (Apr 2010). Proton magnetic resonance spectroscopy and ultrasound for hepatic fat quantification. Hepatol Res. 40:399-406. DOI.
  • Loh WJ; North BV; Johnston DG; Godsland IF. (May 2010). Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up. Cancer Causes Control. 21:709-718. DOI.
  • Forbes S; Robinson S; Parker KH; MacDonald IA; McCarthy MI; Johnston DG. (1 Nov 2009). The thermic response to food is related to sensitivity to adrenaline in a group at risk for the development of type II diabetes. EUROPEAN JOURNAL OF CLINICAL NUTRITION. 63:1360-1367. Author weblink DOI.
  • Varghese A; Yee MS; Chan CF; Crowe LA; Keenan NG; Johnston DG; Pennell DJ. (2009). Effect of rosiglitazone on progression of atherosclerosis: insights using 3D carotid cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 11:24. DOI.
  • Oliver NS; Toumazou C; Cass AE; Johnston DG. (Mar 2009). Glucose sensors: a review of current and emerging technology. Diabet Med. 26:197-210. DOI.
  • Godsland IF; Johnston DG. (1 Sep 2008). Co-associations between insulin sensitivity and measures of liver function, subclinical inflammation, and hematology. METABOLISM-CLINICAL AND EXPERIMENTAL. 57:1190-1197. Author weblink DOI.
  • Atta M; Crook D; Shafique F; Johnston DG; Godsland IF. (1 Sep 2008). Procoagulant activities of plasma factor VIIc and factor Xc are positively and independently associated with concentrations of the high-density lipoprotein apolipoprotein, apoA-II. THROMBOSIS AND HAEMOSTASIS. 100:391-396. Author weblink DOI.
  • Mehta SR; Thomas EL; Bell JD; Johnston DG; Taylor-Robinson SD. (14 Jun 2008). Non-invasive means of measuring hepatic fat content. World J Gastroenterol. 14:3476-3483.
  • Yee MS; Pavitt DV; Tan T; Venkatesan S; Godsland IF; Richmond W; Johnston DG. (Jun 2008). Lipoprotein separation in a novel iodixanol density gradient, for composition, density, and phenotype analysis. J Lipid Res. 49:1364-1371. DOI.
  • Sharp PS; Johnston DG. (Jul 1990). Growth hormone and the microvascular complications of diabetes. Trends Endocrinol Metab. 1:315-318.
  • Portman O; Flemming S; Cox JP; Johnston DG; Bydder GM. (Mar 2008). Magnetic resonance imaging of the normal pituitary gland using ultrashort TE (UTE) pulse sequences (REV 1.0). Neuroradiology. 50:213-220. DOI.
  • Laspa E; Christen A; Efstathiadou Z; Johnston DG; Godsland IF. (1 Nov 2007). Long-term changes and variability in diabetes risk factors prior to the development of impaired glucose homeostasis. DIABETIC MEDICINE. 24:1269-1278. Author weblink DOI.
  • Christen A; Efstathiadou Z; Laspa E; Johnston DG; Godsland IF. (1 Oct 2007). Rate of change and instability in body mass index, insulin resistance, and lipid metabolism as predictors of atherosclerotic vascular disease. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 92:3780-3787. Author weblink DOI.
  • Kousta E; Lawrence NJ; Godsland IF; Penny A; Anyaoku V; Millauer BA; Robinson S; Johnston DG; et alMcCarthy MI. (Apr 2007). Early metabolic defects following gestational diabetes in three ethnic groups of anti-GAD antibodies negative women with normal fasting glucose. Hormones (Athens). 6:138-147.
  • Gallager JJ; Gray RM; Bannister PA; Chrisoulidou A; Robinson ACJ; Johnston DG; Venkatesan S. (Nov 1997). Turnover of pro- and mature apolipoprotein A-I in diabetic patients and normolipidaemic controls. BIOCHEM SOC T. 25:S686-S686.
  • Leonce J; Brockton N; Robinson S; Venkatesan S; Bannister P; Raman V; Murphy K; Parker K; et alPavitt D; Teoh TG; Regan L; Burchell A; Steer P; Johnston DG. (Apr 2006). Glucose production in the human placenta. PLACENTA. 27:S103-S108.
  • Godsland IF; Johnston DG; Chaturvedi N. (1 Jul 2007). Mechanisms of Disease: lessons from ethnicity in the role of triglyceride metabolism in ischemic heart disease. NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM. 3:530-538. Author weblink DOI.
  • Johnston DG. (2004). NICE guidance on Type 1 diabetes in adults. Clinical Medicine. 4:491-493.
  • Englegau MM; Colagiuri S; Ramachandran A; Borch-Johnsen K; Narayan KMV. (2004). Prevention of Type 2 diabetes: issues and strategies for identifying persons for interventions. Diabetes, Technology & Therapeutics. 6:874-882.
  • Mehta SR; Godsland IF; Thomas EL; Bell JD; Patel N; Fitzpatrick J; Durighel G; Westerland O; et alAnyakou U; Pavitt D; Taylor-Robinson SD; Johnston DG. (1 Mar 2007). Relationship between intrahepatocellular lipid content and features of the metabolic syndrome in subjects with known nonalcoholic fatty liver disease and healthy volunteers. DIABETIC MEDICINE. 24:45-46. Author weblink.
  • Godsland IF; Loh WJ; Johnston DG. (1 Mar 2007). Insulin and cancer mortality during 19.2 years of follow-up in the heart disease and diabetes risk in a screened cohort (HDDRISC) study. DIABETIC MEDICINE. 24:25-26. Author weblink.
  • Godsland IF; Lecamwasam KL; Johnston DG. (1 Mar 2007). Surrogate indices of the insulin resistance syndrome as predictors of atherosclerotic vascular disease during 9.4 years follow-up. DIABETIC MEDICINE. 24:25-25. Author weblink.
  • Matthews DR; Kennedy ED; Darbyshire JH; Johnston DG. (1 Jan 2007). The UK Diabetes Research Network - an opportunity and a challenge. DIABETIC MEDICINE. 24:7-9. Author weblink DOI.
  • Forbes S; Robinson S; Dungu J; Anyaoku V; Bannister P; Forster D; Dissanayake S; McCarthy MI; et alMacDonald IA; Venkatesan S; Johnston DG. (Sep 2006). Sustained endogenous glucose production, diminished lipolysis and non-esterified fatty acid appearance and oxidation in non-obese women at high risk of type 2 diabetes. Eur J Endocrinol. 155:469-476. DOI.
  • ROBINSON S; JOHNSTON DG. (22 Jun 1995). ADVANTAGE OF DIABETES. NATURE. 375:640-640. Author weblink DOI.
  • McAinsh AM; Turner MA; OHare D; Nithythyananthan R; Johnston DG; OGorman DJ; Sheridan DJ. (1 Dec 1995). Cardiac hypertrophy impairs recovery from ischaemia because there is a reduced reactive hyperaemic response (vol 30, pg 113, 1995). CARDIOVASCULAR RESEARCH. 30:1044-1044. Author weblink DOI.
  • Kong C; Nimmo L; Anyaoku VN; McColl A; Richmond W; Johnston DG; Robinson S; Elkeles RS. (1 Jun 1997). Insulin insensitivity, minimal modelling and hepatic lipase activity in the dyslipidaemia of type 2 diabetes. DIABETOLOGIA. 40:1659-1659. Author weblink.
  • Robinson ACJ; Johnston DG; Robinson S; Burke J; Elkeles RS. (1 Jun 1997). Glycaemic control of poorly controlled insulin treated type II diabetic patients is improved by metformin therapy. DIABETOLOGIA. 40:1353-1353. Author weblink.
  • Kong C; Anyaoku VN; Batty S; Chong P; Goulis DG; Johnston DG; Elkeles RS; Robinson S. (1 Jun 1997). Insulin resistance measured with specific insulin assay and minimal modelling in subjects with NIDDM. DIABETOLOGIA. 40:1137-1137. Author weblink.
  • Kousta E; Anyaoku V; Goulis DG; Batty S; Kong C; Johnston DG; McCarthy M; Robinson S. (1 Jun 1997). Specific insulin essay demonstrates insulin resistance in women who have bad gestational diabetes mellitus. DIABETOLOGIA. 40:855-855. Author weblink.
  • Saker PJ; Kousta E; Goulis DG; Robinson S; Dornhorst A; Johnston DG; Hitman GA; McCarthy MI. (1 Jun 1997). Screening of candidate genes involved in regulation of thermogenesis amongst gestational diabetic subjects. DIABETOLOGIA. 40:707-707. Author weblink.
  • Kalidas K; Dow E; Saker PJ; Walker M; Gelding SV; McCarthy MI; Johnston DG. (1 Jun 1997). Linkage analysis and molecular scanning of the PC3 gene in NIDDM. DIABETOLOGIA. 40:629-629. Author weblink.
  • AlShoumer KAS; Anyaoku V; Ali K; Johnston DG. (1 May 1997). Metabolic effects of short-term reproduction of the normal diurnal cortisol rhythm in hypopituitary adults. ENDOCRINOLOGY AND METABOLISM. 4:207-214. Author weblink.
  • Saker PJ; Huxtable SJ; Kousla E; Robinson S; Gharani N; Conway G; Franks S; Warden C; et alHitman GA; Johnston DG; McCarthy MI. (1 Aug 1998). Adrenergic receptor and uncoupling protein gene variants and susceptibility to NIDDM and related conditions. DIABETOLOGIA. 41:A110-A110. Author weblink.
  • Kousta E; Lawrence NJ; Penny A; Millauer B; Mulnier H; Johnston DG; Robinson S; McCarthy MI. (1 Aug 1999). Insulin resistance is the predominant feature in normoglycaemic women with previous gestational diabetes. DIABETOLOGIA. 42:A161-A161. Author weblink.
  • Lawrence NJ; Kousta E; Mulnier H; Penny A; Millauer B; Johnston DG; Robinson S; McCarthy MI. (1 Aug 1999). Normoglycaemic women with previous gestational diabetes have decreased postprandial energy expenditure. DIABETOLOGIA. 42:A53-A53. Author weblink.
  • Kousta E; Lawrence NJ; Penny A; Cela E; Millauer BA; Robinson S; Johnston DG; McCarthy MI. (1 Aug 2000). Women from different ethnic groups display divergent relationships between insulin sensitivity and lipid profiles. DIABETOLOGIA. 43:A291-A291. Author weblink.
  • Smith MR; Anyaoku V; Johnston DG; Robinson S. (1 Aug 2001). Disordered kinetics of exogenous insulin in type 2 diabetes: A study of insulin volume of distribution and metabolic clearance in diabetic and non-diabetic subjects. DIABETOLOGIA. 44:A158-A158. Author weblink.
  • Virjee S; Teoh TG; Johnston DG; Robinson S. (1 Aug 2001). The benefits of the thrifty genotype. DIABETOLOGIA. 44:A85-A85. Author weblink.
  • Liew CF; Groves CJ; Wiltshire S; Zeggini E; Frayling TM; Owen KR; Walker M; Hitman GA; et alLevy JC; O'Rahilly S; Hattersley AT; Johnston DG; McCarthy MI. (1 Dec 2004). Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism. DIABETOLOGIA. 47:2168-2175. Author weblink DOI.
  • Godsland IF; Johnston DG. (1 Oct 2005). Reply to comment on: Godsland IF, Jeffs JA, Johnston DG (2004) Loss of beta cell function as fasting glucose increases in the non-diabetic range. Diabetologia 47 : 1157-1166. DIABETOLOGIA. 48:2189-2190. Author weblink DOI.
  • Jeffs JA; Godsland IF; Johnston DG. (Jan 2006). Less than 50% of variation in HDL cholesterol between and within individuals, is explained by established predictors. Atherosclerosis. 184:178-187. DOI.
  • Kousta E; Efstathiadou Z; Lawrence NJ; Jeffs JA; Godsland IF; Barrett SC; Doré CJ; Penny A; et alAnyaoku V; Millauer BA; Cela E; Robinson S; McCarthy MI; Johnston DG. (Jan 2006). The impact of ethnicity on glucose regulation and the metabolic syndrome following gestational diabetes. Diabetologia. 49:36-40. DOI.
  • Tillin T; Forouhi N; Johnston DG; McKeigue PM; Chaturvedi N; Godsland IF. (Apr 2005). Metabolic syndrome and coronary heart disease in South Asians, African-Caribbeans and white Europeans: a UK population-based cross-sectional study. Diabetologia. 48:649-656. DOI.
  • Forbes S; Moonan M; Robinson S; Anyaoku V; Patterson M; Murphy KG; Ghatei MA; Bloom SR; et alJohnston DG. (Jan 2005). Impaired circulating glucagon-like peptide-1 response to oral glucose in women with previous gestational diabetes. Clin Endocrinol (Oxf). 62:51-55. DOI.
  • Hannan FM; Fairney A; Johnston DG. (Sep 2004). Vitamin D deficiency masking primary hyperparathyroidism. Ann Clin Biochem. 41:405-407. DOI.
  • Williamson C; Hems LM; Goulis DG; Walker I; Chambers J; Donaldson O; Swiet M; Johnston DG. (Jul 2004). Clinical outcome in a series of cases of obstetric cholestasis identified via a patient support group. BJOG. 111:676-681. DOI.
  • Godsland IF; Jeffs JA; Johnston DG. (Jul 2004). Loss of beta cell function as fasting glucose increases in the non-diabetic range. Diabetologia. 47:1157-1166. DOI.
  • Jolly M; Bertie J; Gray R; Bannister P; Venkatesan S; Johnston D; Robinson S. (May 2004). Increased leucine turnover in women during the third trimester of uncomplicated pregnancy. Metabolism. 53:545-549.
  • Albrecht C; Simon-Vermot I; Elliott JI; Higgins CF; Johnston DG; Valabhji J. (Jan 2004). Leukocyte ABCA1 gene expression is associated with fasting glucose concentration in normoglycemic men. Metabolism. 53:17-21.
  • Robinson AC; Jeffs JA; Gray RG; Bannister PA; Mather H; Gallagher JJ; Robinson S; Nattrass M; et alVenkatesan S; Halliday D; Johnston DG. (Jan 2004). Metabolic effects of Troglitazone in patients with diet-controlled type 2 diabetes. Eur J Clin Invest. 34:29-36.
  • Kousta E; Lawrence NJ; Godsland IF; Penny A; Anyaoku V; Millauer BA; Cela E; Johnston DG; et alRobinson S; McCarthy MI. (Sep 2003). Insulin resistance and beta-cell dysfunction in normoglycaemic European women with a history of gestational diabetes. Clin Endocrinol (Oxf). 59:289-297.
  • Jolly MC; Hovorka R; Godsland I; Amin R; Lawrence N; Anyaoku V; Johnston D; Robinson S. (Aug 2003). Relation between insulin kinetics and insulin sensitivity in pregnancy. Eur J Clin Invest. 33:698-703.
  • Mullenbach R; Linton KJ; Wiltshire S; Weerasekera N; Chambers J; Elias E; Higgins CF; Johnston DG; et alMcCarthy MI; Williamson C. (1 May 2003). ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy. JOURNAL OF MEDICAL GENETICS. 40. Author weblink DOI.
  • Kearney T; de Gallegos CN; Proudler A; Parker K; Anayaoku V; Bannister P; Venkatesan S; Johnston DG. (Jan 2003). Effects of short- and long-term growth hormone replacement on lipoprotein composition and on very-low-density lipoprotein and low-density lipoprotein apolipoprotein B100 kinetics in growth hormone-deficient hypopituitary subjects. Metabolism. 52:50-59. DOI.
  • Patel P; Weerasekera N; Hitchins M; Boyd CA; Johnston DG; Williamson C. (Jan 2003). Semi quantitative expression analysis of MDR3, FIC1, BSEP, OATP-A, OATP-C,OATP-D, OATP-E and NTCP gene transcripts in 1st and 3rd trimester human placenta. Placenta. 24:39-44.
  • Patel P; Boyd CA; Johnston DG; Williamson C. (Sep 2002). Analysis of GAPDH as a standard for gene expression quantification in human placenta. Placenta. 23:697-698.
  • Johnston DG; Kearney T; Robinson S; Al-Mrayat M. (Aug 2002). Some elucidation of the mechanisms of vascular disease in hypopituitarism. Clin Endocrinol (Oxf). 57:159-160.
  • Kousta E; Parker KH; Lawrence NJ; Penny A; Millauer BA; Anyaoku V; Mulnier H; Forster DC; et alMacDonald IA; Robinson S; McCarthy MI; Johnston DG. (Jul 2002). Delayed metabolic and thermogenic response to a mixed meal in normoglycemic European women with previous gestational diabetes. J Clin Endocrinol Metab. 87:3407-3412.
  • Johnston DG; Robinson S; Forbes S. (Jul 2002). What should we measure in the diabetic patient and how does this respond to therapy?. Br J Clin Pharmacol. 54:81-86.
  • Lawrence NJ; Kousta E; Penny A; Millauer B; Robinson S; Johnston DG; McCarthy MI. (Mar 2002). Elevation of soluble E-selectin levels following gestational diabetes is restricted to women with persistent abnormalities of glucose regulation. Clin Endocrinol (Oxf). 56:335-340.
  • Johnston DG. (Nov 2001). Committee on Publication Ethics 1997-2000. Clin Med. 1:462-463.
  • Virjee S; Robinson S; Johnston DG. (Oct 2001). Screening for diabetes in pregnancy. J R Soc Med. 94:502-509.
  • Kearney T; Navas de Gallegos C; Chrisoulidou A; Gray R; Bannister P; Venkatesan S; Johnston DG. (Aug 2001). Hypopituitarsim is associated with triglyceride enrichment of very low-density lipoprotein. J Clin Endocrinol Metab. 86:3900-3906.
  • Kousta E; Lawrence NJ; Anyaoku V; Johnston DG; McCarthy MI. (Jul 2001). Prevalence and features of pancreatic islet cell autoimmunity in women with gestational diabetes from different ethnic groups. BJOG. 108:716-720.
  • Godsland IF; Rosankiewicz JR; Proudler AJ; Johnston DG. (Feb 2001). Plasma total homocysteine concentrations are unrelated to insulin sensitivity and components of the metabolic syndrome in healthy men. J Clin Endocrinol Metab. 86:719-723.
  • Kousta E; Lawrence NJ; Penny A; Millauer BA; Robinson S; Johnston DG; McCarthy MI. (Nov 2000). Women with a history of gestational diabetes of European and South Asian origin are shorter than women with normal glucose tolerance in pregnancy. Diabet Med. 17:792-797.
  • Chrisoulidou A; Beshyah SA; Rutherford O; Spinks TJ; Mayet J; Kyd P; Anyaoku V; Haida A; et alAriff B; Murphy M; Thomas E; Robinson S; Foale R; Johnston DG. (Oct 2000). Effects of 7 years of growth hormone replacement therapy in hypopituitary adults. J Clin Endocrinol Metab. 85:3762-3769.
  • Kousta E; Cela E; Lawrence N; Penny A; Millauer B; White D; Wilson H; Robinson S; et alJohnston D; McCarthy M; Franks S. (Oct 2000). The prevalence of polycystic ovaries in women with a history of gestational diabetes. Clin Endocrinol (Oxf). 53:501-507.
  • Chrisoulidou A; Kousta E; Venkatesan S; Gray R; Bannister PA; Gallagher JJ; Lawrence N; Johnston DG. (May 2000). Effects of growth hormone treatment on very-low density lipoprotein apolipoprotein B100 turnover in adult hypopituitarism. Metabolism. 49:563-566.
  • Dixon PH; Weerasekera N; Linton KJ; Donaldson O; Chambers J; Egginton E; Weaver J; Nelson-Piercy C; et alde Swiet M; Warnes G; Elias E; Higgins CF; Johnston DG; McCarthy MI; Williamson C. (1 May 2000). Heterozygous MDR3 missense mutation associated with intrahepatic cholestasis of pregnancy: evidence for a defect in protein trafficking. Hum Mol Genet. 9:1209-1217.
  • Kearney T; Robinson S; Johnston DG. (Jan 2000). Isolated corticotropin deficiency in chronic alcoholism. J R Soc Med. 93:15-17.
  • Kousta E; Chrisoulidou A; Lawrence NJ; Anyaoku V; Al-Shoumer KA; Johnston DG. (Jan 2000). The effects of growth hormone replacement therapy on overnight metabolic fuels in hypopituitary patients. Clin Endocrinol (Oxf). 52:17-24.
  • Prendergast CH; Parker KH; Gray R; Venkatesan S; Bannister P; Castro-Soares J; Murphy KW; Beard RW; et alRegan L; Robinson S; Steer P; Halliday D; Johnston DG. (Sep 1999). Glucose production by the human placenta in vivo. Placenta. 20:591-598. DOI.
  • Chrisoulidou A; Kousta E; Venkatesan S; Gray R; Bannister PA; Gallagher JJ; Johnston DG. (Aug 1999). Very-low-density lipoprotein apolipoprotein B100 kinetics in adult hypopituitarism. Metabolism. 48:1057-1062.
  • Kousta E; Lawrence NJ; Penny A; Millauer BA; Robinson S; Dornhorst A; de Swiet M; Steer PJ; et alGrenfell A; Mather HM; Johnston DG; McCarthy MI. (Jun 1999). Implications of new diagnostic criteria for abnormal glucose homeostasis in women with previous gestational diabetes. Diabetes Care. 22:933-937.
  • Beshyah SA; Johnston DG. (Jan 1999). Cardiovascular disease and risk factors in adults with hypopituitarism. Clin Endocrinol (Oxf). 50:1-15.
  • Johnston DG; Al-Shoumer KA; Chrisoulidou A; Kousta E; Beshyah S; Robinson S. (1999). Long-term effects of growth hormone therapy on intermediary metabolism and insulin sensitivity in hypopituitary adults. J Endocrinol Invest. 22:37-40.
  • Chrisoulidou A; Kousta E; Beshyah SA; Robinson S; Johnston DG. (Jul 1998). How much, and by what mechanisms, does growth hormone replacement improve the quality of life in GH-deficient adults?. Baillieres Clin Endocrinol Metab. 12:261-279.
  • al-Shoumer KA; Gray R; Anyaoku V; Hughes C; Beshyah S; Richmond W; Johnston DG. (Jun 1998). Effects of four years' treatment with biosynthetic human growth hormone (GH) on glucose homeostasis, insulin secretion and lipid metabolism in GH-deficient adults. Clin Endocrinol (Oxf). 48:795-802.
  • Kousta E; Chrisoulidou A; Lawrence NJ; al-Shoumer KA; Parker KH; McCarthy MI; Johnston DG. (Jun 1998). The circadian rhythm of leptin is preserved in growth hormone deficient hypopituitary adults. Clin Endocrinol (Oxf). 48:685-690.
  • Robinson AC; Burke J; Robinson S; Johnston DG; Elkeles RS. (May 1998). The effects of metformin on glycemic control and serum lipids in insulin-treated NIDDM patients with suboptimal metabolic control. Diabetes Care. 21:701-705.
  • Kalidas K; Dow E; Saker PJ; Wareham N; Halsall D; Jackson RS; Chan SP; Gelding S; et alWalker M; Kousta E; Johnston DG; O'Rahilly S; McCarthy MI. (Feb 1998). Prohormone convertase 1 in obesity, gestational diabetes mellitus, and NIDDM: no evidence for a major susceptibility role. Diabetes. 47:287-289.
  • Ding C; Bordin P; Gray RM; Bannister PA; Johnston DG; Venkatesan S. (Nov 1997). Changes in fatty acid profile in plasma and very low density lipoprotein lipids after fish oil supplementation. Biochem Soc Trans. 25:S687.
  • al-Shoumer KA; Anyaoku V; Richmond W; Johnston DG. (Aug 1997). Elevated leptin concentrations in growth hormone-deficient hypopituitary adults. Clin Endocrinol (Oxf). 47:153-159.
  • al-Shoumer KA; Cox KH; Hughes CL; Richmond W; Johnston DG. (Aug 1997). Fasting and postprandial lipid abnormalities in hypopituitary women receiving conventional replacement therapy. J Clin Endocrinol Metab. 82:2653-2659.
  • Johnston DG. (Apr 1997). Growth hormone deficiency and quality of life in hypopituitary adults. Clin Endocrinol (Oxf). 46:407-408.
  • Markussis V; Beshyah SA; Fisher C; Parker KH; Nicolaides AN; Johnston DG. (Feb 1997). Abnormal carotid arterial wall dynamics in symptom-free hypopituitary adults. Eur J Endocrinol. 136:157-164.
  • Al-Shoumer KA; Page B; Thomas E; Murphy M; Beshyah SA; Johnston DG. (Nov 1996). Effects of four years' treatment with biosynthetic human growth hormone (GH) on body composition in GH-deficient hypopituitary adults. Eur J Endocrinol. 135:559-567.
  • Al-Shoumer KA; Ali K; Anyaoku V; Niththyananthan R; Johnston DG. (Aug 1996). Overnight metabolic fuel deficiency in patients treated conventionally for hypopituitarism. Clin Endocrinol (Oxf). 45:171-178.
  • Robinson S; Henderson AD; Gelding SV; Kiddy D; Niththyananthan R; Bush A; Richmond W; Johnston DG; et alFranks S. (Mar 1996). Dyslipidaemia is associated with insulin resistance in women with polycystic ovaries. Clin Endocrinol (Oxf). 44:277-284.
  • Beshyah SA; Gelding SV; Andres C; Johnston DG; Gray IP. (Sep 1995). Beta-cell function in hypopituitary adults before and during growth hormone treatment. Clin Sci (Lond). 89:321-328.
  • Johnston DG; Beard RW; Chan SP; Dornhorst A; Elkeles RS; Gelding SV; Nicholls JS; Robinson S. (Aug 1995). Aspects of metabolism in normal and gestational diabetic pregnancy. Biochem Soc Trans. 23:512-516.
  • McAinsh AM; Turner MA; O'Hare D; Nithythyananthan R; Johnston DG; O'Gorman DJ; Sheridan DJ. (Jul 1995). Cardiac hypertrophy impairs recovery from ischaemia because there is a reduced reactive hyperaemic response. Cardiovasc Res. 30:113-121.
  • Beshyah SA; Freemantle C; Thomas E; Johnston DG. (Jun 1995). Comparison of measurements of body composition by total body potassium, bioimpedance analysis, and dual-energy X-ray absorptiometry in hypopituitary adults before and during growth hormone treatment. Am J Clin Nutr. 61:1186-1194.
  • Gelding SV; Andres C; Niththyananthan R; Gray IP; Mather H; Johnston DG. (Mar 1995). Increased secretion of 32,33 split proinsulin after intravenous glucose in glucose-tolerant first-degree relatives of patients with non-insulin dependent diabetes of European, but not Asian, origin. Clin Endocrinol (Oxf). 42:255-264.
  • Beshyah SA; Kyd P; Thomas E; Fairney A; Johnston DG. (Mar 1995). The effects of prolonged growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults. Clin Endocrinol (Oxf). 42:249-254.
  • Beshyah SA; Freemantle C; Thomas E; Rutherford O; Page B; Murphy M; Johnston DG. (Feb 1995). Abnormal body composition and reduced bone mass in growth hormone deficient hypopituitary adults. Clin Endocrinol (Oxf). 42:179-189.
  • Beshyah SA; Henderson A; Niththyananthan R; Skinner E; Anyaoku V; Richmond W; Sharp P; Johnston DG. (Feb 1995). The effects of short and long-term growth hormone replacement therapy in hypopituitary adults on lipid metabolism and carbohydrate tolerance. J Clin Endocrinol Metab. 80:356-363.
  • Beshyah SA; Shahi M; Foale R; Johnston DG. (Jan 1995). Cardiovascular effects of prolonged growth hormone replacement in adults. J Intern Med. 237:35-42.
  • Rutherford OM; Beshyah SA; Schott J; Watkins Y; Johnston DG. (Jan 1995). Contractile properties of the quadriceps muscle in growth hormone-deficient hypopituitary adults. Clin Sci (Lond). 88:67-71.
  • al-Shoumer KA; Beshyah SA; Niththyananthan R; Johnston DG. (Jan 1995). Effect of glucocorticoid replacement therapy on glucose tolerance and intermediary metabolites in hypopituitary adults. Clin Endocrinol (Oxf). 42:85-90.
  • Gelding SV; Coldham N; Niththyananthan R; Anyaoku V; Johnston DG. (Jan 1995). Insulin resistance with respect to lipolysis in non-diabetic relatives of European patients with type 2 diabetes. Diabet Med. 12:66-73.
  • Beshyah SA; Henderson A; Baynes C; Copping D; Richmond W; Johnston DG. (1995). Post-heparin plasma lipase activity in hypopituitary adults. Horm Res. 44:69-74.
  • Beshyah SA; Freemantle C; Shahi M; Anyaoku V; Merson S; Lynch S; Skinner E; Sharp P; et alFoale R; Johnston DG. (Jan 1995). Replacement treatment with biosynthetic human growth hormone in growth hormone-deficient hypopituitary adults. Clin Endocrinol (Oxf). 42:73-84.
  • Dow E; Gelding SV; Skinner E; Hewitt JE; Gray IP; Mather H; Williamson R; Johnston DG. (Nov 1994). Genetic analysis of glucokinase and the chromosome 20 diabetes susceptibility locus in families with type 2 diabetes. Diabet Med. 11:856-861.
  • Gelding SV; Andres C; Niththyananthan R; Richmond W; Gray IP; Johnston DG. (Oct 1994). Serum lipoprotein levels and plasma concentrations of insulin, intact and 32, 33 split proinsulin in normoglycaemic relatives of patients with type 2 diabetes. Diabet Med. 11:748-754.
  • Lynch S; Merson S; Beshyah SA; Skinner E; Sharp P; Priest RG; Johnston DG. (Aug 1994). Psychiatric morbidity in adults with hypopituitarism. J R Soc Med. 87:445-447.
  • Robinson S; Niththyananthan R; Anyaoku V; Elkeles RS; Beard RW; Johnston DG. (Jul 1994). Reduced postprandial energy expenditure in women predisposed to type 2 diabetes. Diabet Med. 11:545-550.
  • Beshyah SA; Shahi M; Skinner E; Sharp P; Foale R; Johnston DG. (May 1994). Cardiovascular effects of growth hormone replacement therapy in hypopituitary adults. Eur J Endocrinol. 130:451-458.
  • Gelding SV; Robinson S; Lowe S; Niththyananthan R; Johnston DG. (May 1994). Validation of the low dose short insulin tolerance test for evaluation of insulin sensitivity. Clin Endocrinol (Oxf). 40:611-615.
  • Beshyah SA; Thomas E; Kyd P; Sharp P; Fairney A; Johnston DG. (Mar 1994). The effect of growth hormone replacement therapy in hypopituitary adults on calcium and bone metabolism. Clin Endocrinol (Oxf). 40:383-391.
  • Gelding SV; Niththyananthan R; Chan SP; Skinner E; Robinson S; Gray IP; Mather H; Johnston DG. (Jan 1994). Insulin sensitivity in non-diabetic relatives of patients with non-insulin-dependent diabetes from two ethnic groups. Clin Endocrinol (Oxf). 40:55-62.
  • Robinson S; Kiddy D; Gelding SV; Willis D; Niththyananthan R; Bush A; Johnston DG; Franks S. (Sep 1993). The relationship of insulin insensitivity to menstrual pattern in women with hyperandrogenism and polycystic ovaries. Clin Endocrinol (Oxf). 39:351-355.
  • Beshyah SA; Markussis V; Harbourne T; Nicolaides AN; Johnston DG. (Aug 1993). Haemostatic mechanisms are normal despite increased vascular mortality in hypopituitary adults. Horm Metab Res. 25:449-450. DOI.
  • Beshyah SA; Sharp PS; Gelding SV; Halliday D; Johnston DG. (Aug 1993). Whole-body leucine turnover in adults on conventional treatment for hypopituitarism. Acta Endocrinol (Copenh). 129:158-164.
  • Gelding SV; Coldham N; Anyaoku V; Heslop K; Halliday D; Johnston DG. (Jun 1993). Differential metabolic actions of biosynthetic insulin analogues in normal man assessed by stable isotopic tracers. Diabet Med. 10:470-476.
  • Anyaoku VN; Wood DF; Pavlou R; Williams P; Tan K; Fidler S; Johnston DG. (Mar 1993). An enzyme-linked immunoadsorbent assay for human pituitary glycoprotein free alpha-subunit: evaluation and initial experience in patients with pituitary disease. J Endocrinol. 136:511-516.
  • Johnston JM; Wood DF; Read S; Johnston DG. (Mar 1993). Dopamine regulates D2 receptor gene expression in normal but not in tumorous rat pituitary cells. Mol Cell Endocrinol. 92:63-68.
  • Robinson S; Viira J; Learner J; Chan SP; Anyaoku V; Beard RW; Johnston DG. (Mar 1993). Insulin insensitivity is associated with a decrease in postprandial thermogenesis in normal pregnancy. Diabet Med. 10:139-145.
  • Baynes C; Elkeles RS; Henderson AD; Richmond W; Johnston DG. (Feb 1993). The effects of glibenclamide on glucose homeostasis and lipoprotein metabolism in poorly controlled type 2 diabetes. Horm Metab Res. 25:96-101. DOI.
  • Markussis V; Beshyah SA; Fisher C; Sharp P; Nicolaides AN; Johnston DG. (14 Nov 1992). Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults. Lancet. 340:1188-1192.
  • Dornhorst A; Paterson CM; Nicholls JS; Wadsworth J; Chiu DC; Elkeles RS; Johnston DG; Beard RW. (Nov 1992). High prevalence of gestational diabetes in women from ethnic minority groups. Diabet Med. 9:820-825.
  • Sharp PS; Beshyah SA; Johnston DG. (Oct 1992). Growth hormone disorders and secondary diabetes. Baillieres Clin Endocrinol Metab. 6:819-828.
  • Johnston JM; Wood DF; James JD; Johnston DG. (Aug 1992). Preparation and characterization of an antibody specific to the rat dopamine D2 receptor. J Endocrinol. 134:227-233.
  • Robinson S; Chan SP; Spacey S; Anyaoku V; Johnston DG; Franks S. (Jun 1992). Postprandial thermogenesis is reduced in polycystic ovary syndrome and is associated with increased insulin resistance. Clin Endocrinol (Oxf). 36:537-543.
  • Baynes C; Henderson AD; Richmond W; Johnston DG; Elkeles RS. (May 1992). The response of hepatic lipase and serum lipoproteins to acute hyperinsulinaemia in type 2 diabetes. Eur J Clin Invest. 22:341-346.
  • Chan SP; Gelding SV; McManus RJ; Nicholls JS; Anyaoku V; Niththyananthan R; Johnston DG; Dornhorst A. (Apr 1992). Abnormalities of intermediary metabolism following a gestational diabetic pregnancy. Clin Endocrinol (Oxf). 36:417-420.
  • Dornhorst A; Chan SP; Gelding SV; Nicholls JS; Baynes C; Elkeles RS; Beard RW; Anyaoku V; et alJohnston DG. (Apr 1992). Ethnic differences in insulin secretion in women at risk of future diabetes. Diabet Med. 9:258-262.
  • Rogers ME; Williams DT; Niththyananthan R; Rampling MW; Heslop KE; Johnston DG. (Mar 1992). Decrease in erythrocyte glycophorin sialic acid content is associated with increased erythrocyte aggregation in human diabetes. Clin Sci (Lond). 82:309-313.
  • Johnston DG; Beshyah SA; Markussis V; Shahi M; Sharp PS; Foale RA; Skinner EM. (1992). Metabolic changes and vascular risk factors in hypopituitarism. Horm Res. 38 Suppl 1:68-72.
  • Shahi M; Beshyah SA; Hackett D; Sharp PS; Johnston DG; Foale RA. (Jan 1992). Myocardial dysfunction in treated adult hypopituitarism: a possible explanation for increased cardiovascular mortality. Br Heart J. 67:92-96.
  • Wood DF; Johnston JM; Johnston DG. (Dec 1991). Dopamine, the dopamine D2 receptor and pituitary tumours. Clin Endocrinol (Oxf). 35:455-466.
  • Baynes C; Anyaoku V; Johnston DG; Elkeles RS. (Nov 1991). Feedback inhibition of insulin secretion in type 2 diabetes. Clin Sci (Lond). 81:685-690.
  • Beshyah SA; Anyaoku V; Niththyananthan R; Sharp P; Johnston DG. (Nov 1991). The effect of subcutaneous injection site on absorption of human growth hormone: abdomen versus thigh. Clin Endocrinol (Oxf). 35:409-412.
  • Johnston JM; Wood DF; Bolaji EA; Johnston DG. (Oct 1991). The dopamine D2 receptor is expressed in GH3 cells. J Mol Endocrinol. 7:131-136.
  • Sharp PS; Kiddy DS; Reed MJ; Anyaoku V; Johnston DG; Franks S. (Sep 1991). Correlation of plasma insulin and insulin-like growth factor-I with indices of androgen transport and metabolism in women with polycystic ovary syndrome. Clin Endocrinol (Oxf). 35:253-257.
  • Dornhorst A; Edwards SG; Nicholls JS; Anyaoku V; McLaren D; Heslop KE; Elkeles RS; Beard RW; et alJohnston DG. (Aug 1991). A defect in insulin release in women at risk of future non-insulin-dependent diabetes. Clin Sci (Lond). 81:195-199.
  • Baynes C; Henderson AD; Anyaoku V; Richmond W; Hughes CL; Johnston DG; Elkeles RS. (Jul 1991). The role of insulin insensitivity and hepatic lipase in the dyslipidaemia of type 2 diabetes. Diabet Med. 8:560-566.
  • Baynes C; Henderson AD; Anyaoku V; Richmond W; Johnston DG; Elkeles RS. (Jun 1991). The influence of regional adiposity on atherogenic risk factors in men and women with type 2 diabetes. Diabet Med. 8:458-463.
  • Dornhorst A; Davies M; Anyaoku V; Hampton SM; Elkeles RS; Beard RW; Johnston DG. (Mar 1991). Abnormalities in fasting circulating proinsulin concentration in mild gestational diabetes. Clin Endocrinol (Oxf). 34:211-213.
  • Baynes C; Henderson AD; Hughes CL; Richmond W; Johnston DG; Elkeles RS. (Mar 1991). Determinants of mild fasting hypertriglyceridaemia in non-insulin-dependent diabetes. J Intern Med. 229:267-273.
  • Dornhorst A; Bailey PC; Anyaoku V; Elkeles RS; Johnston DG; Beard RW. (Dec 1990). Abnormalities of glucose tolerance following gestational diabetes. Q J Med. 77:1219-1228.
  • Wood DF; Goodchild K; Guillou P; Thomas DJ; Johnston DG. (17 Nov 1990). Management of "brittle" diabetes with a preprogrammable implanted insulin pump delivering intraperitoneal insulin. BMJ. 301:1143-1144.
  • BARNES AJ; KOHNER EM; JOHNSTON DG; ALBERTI KGMM. (1 Jan 1985). SEVERE RETINOPATHY AND MILD CARBOHYDRATE INTOLERANCE - POSSIBLE ROLE OF INSULIN DEFICIENCY AND ELEVATED CIRCULATING GROWTH-HORMONE. LANCET. 1:1465-1468. Author weblink.
  • JOHNSTON DG; ALBERTI KGMM; NATTRASS M; BARNES AJ; BLOOM S; JOPLIN GF. (1 Jan 1980). HORMONAL AND METABOLIC RHYTHMS IN CUSHINGS-SYNDROME. METABOLISM-CLINICAL AND EXPERIMENTAL. 29:1046-1052. Author weblink DOI.
  • BARNES AJ; KOHNER EM; BLOOM S; JOHNSTON DG; ALBERTI KGMM; SMYTHE P. (1 Jan 1978). IMPORTANCE OF PITUITARY HORMONES IN ETIOLOGY OF DIABETIC KETOACIDOSIS. LANCET. 1:1171-1174. Author weblink.
  • BARNES AJ; KOHNER EM; BLOOM S; JOHNSTON DG; SMYTHE P. (1 Jan 1977). IMPORTANCE OF PITUITARY IN DEVELOPMENT OF DIABETIC KETOACIDOSIS. DIABETOLOGIA. 13:380-380. Author weblink.
  • JOHNSTON DG; ALBERTI KGMM; HINKS L; SMYTHE P; BARNES AJ; BLOOM S; JOPLIN GF. (1 Jan 1977). METABOLIC RHYTHMS IN CUSHINGS-SYNDROME. ACTA ENDOCRINOLOGICA. 85:89-89. Author weblink.

Chapters in books

  • Johnston DG; Alberti KGMM; Godsland IF; Pierce M; Shepperd S. Screening for Type 2 diabetes. In Coronary Heart Disease Epidemiology. 2nd Edition:714-750. Marmot M (ed); Elliott P (ed). OUP, Oxford (2005).
  • Johnston DG; Al Mrayat M; Kearney T. Hypopituitarism in adults. In Conn's current therapy. 637-643. (2002).
  • Kearney T; Johnston DG. Pituitary adenomas. In Endocrinology: specialist handbook. 1-19. (2002).

Conferences

  • Patel DC; Pavitt D; Albrecht C; Dhanjil S; Hannen R; Valabhj J; Higgins CF; Johnston DG. Hyperglycaemic patients have decreased ATP-binding cassette transporter-A1 (ABCA-1) gene expression: A novel disease mechanism. 22nd Annual Conference of HEART UK. 199:231-232. (Jul 2008).
  • Patel DC; Albrecht C; Pavitt D; Pourreyron C; Valabhji J; Higgins CF; Johnston DG. Hyperglycemia specifically correlates with ATP-Binding Cassette Transporter-A1 gene expression and function in humans. 9th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology, 16 Apr 2008 - 18 Apr 2008. 28:E96-E96. LIPPINCOTT WILLIAMS & WILKINS (1 Jun 2008). Author weblink.
  • Mehta SR; Barton N; Godsland IF; Robinson S; Bell JD; Thomas EL; Patel N; Fitzpatrick J; et alDurighel G; Pavitt D; Taylor-Robinson SD; Johnston DG. Impaired insulin-mediated non-esterified fatty acid suppression in patients with hepatic steatosis quantified using proton magnetic resonance spectroscopy. 43rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes. 50:S295-S296. (Sep 2007).
  • Smith MR; Anyaoku V; Johnston DG; Robinson S. The whole body kinetics of insulin: insulin resistance is associated with reduced insulin volume of distribution and slower plasma clearance of insulin in Type 2 diabetes and non diabetic subjects. 38th EASD Annual Meeting of the European-Association-for-the-Study-of-Diabetes. 45:A184-A184. (Aug 2002).
  • Godsland IF; Johnston DG. Extending the metabolic syndrome: Insulin sensitivity, liver function, subclinical inflammation and haematological measures. 19th Annual Medical and Scientific Meeting of HEART UK, 30 Jun 2005 - 1 Jul 2005. 182:S3-S3. ELSEVIER IRELAND LTD (1 Sep 2005). Author weblink.
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