Contact details
Mr Daniel Reed
Daniel Reed is a PhD student at the National Heart and Lung Institute, Imperial College London.
Daniel obtained his BSc. Honours degree in Pharmacology in 2009 from the University of Liverpool during which he was awarded the Syngenta Prize for Pharmacology.
As of 2009, Daniel holds an MRC funded studentship within the Faculty of Medicine and is carrying out his research with Prof. Jane A. Mitchell, Dr Mark Paul-Clark, Prof. Sian Harding and Dr Gabor Foldes at the National Heart Lung Institute.
His research focusses on the pharmacology and function of stem cell derived endothelial cells with partciular emphasis on vasoactive genes and pattern recognition receptors (PRRs).Studying these pathways will be important for the optimal use of stem cell derived endothelial cells in both research and in the clinical setting.
Daniel also holds positions on the Young Pharmacologists Committee and the Education and Training Committee at the British Pharmacological Society.
Selected Publications
Conferences
- Wright WR; Kirkby NS; Reed DM; Gashaw HH; Phillips N; Paul-Clark MJ. Investigating the role of cycloxygenase in Toll-like receptor responses in lung fibroblasts. BPS Winter Meeting 2011. pA2 online (Dec 2011).
- Reed DM; Foldes G; Badiger RV; Wheeler-Jones CP; Ali NN; Harding SE; Mitchell JA. TLR3 and Interferon pathways in human embryonic stem cell derived endothelial cells: Implications in viral immunity. British Society of Cardiovascular Research, Jun 2011.
- Gatheral T; Moreno L; Reed DM; Badiger RV; Bailey LK; Galloway-Phillips N; Mitchell JA. Stimulation of NOD1 induces RIP2, TAK-1 and p38 MAPK dependent pro-inflammatory signalling in Human Lung Microvascular Endothelial Cells. European Respiratory Society, Sep 2011.
- Reed DM; Foldes G; Gatheral T; Badiger RV; Ali NN; Wheeler-Jones CP; Harding SE; Mitchell JA. Endothelin-1 pathways in human embryonic stem cell-derived endothelial cells (hESC-EC): Comparisons with primary human endothelial cells. World Congress on Inflammation 2011, Jun 2011. Inflammation Research.
- Parzych K; Wright WR; Crawford DC; Reed DM; Mitchell JA; Paul-Clark MJ. Pharmacology of TLR1 and TLR2 agonists in IL-1β release for human monocytes. BPS Winter Meeting 2010, Dec 2010.
- Parzych K; Reed DM; Paul-Clark MJ. TLR2/1 activation induced proliferation of A549 cells under certain conditions. Toll 2011, Jun 2011.
- Reed DM; Foldes G; Mioulane M; Ali NN; Schneider MD; Harding SE; Mitchell JA. Identification of NF-κB pathways in human embryonic stem cell-derived endothelial cells: comparison with human umbilical vein endothelial cells. BHF Centre for Research Excellence Symposium, Jun 2010.
- Reed DM; Foldes G; Gatheral T; Ali NN; Schneider MD; Harding SE; Mitchell JA. Characterisation of Pattern Recognition Receptor (PRR) function in Human Embryonic Stem cell-derived Endothelial Cells. BPS Winter Meeting 2010, Dec 2010.
- Reed DM; Wright WR; Potter CMF; Gashaw HH; Bailey LK; Paul-Clark MJ; Mitchell JA. TLR3 and TLR4 ligands induce intracellular IL-1β immunoreactivity in human aortic endothelial cells (HAEC) and lung microvascular endothelial cells (HLMVECs). World Congress of Basic and Clinical Pharmacology (WorldPharma 2010), Copenhagen, Denmark, Jul 2010.
