Research

External collaborations

Reckitt-Benkiser, Parsippany, USA, Dr Gail Solomon. Oct 2011 - Oct 2013.

GlaxoSmithKline (UK), Dr Keith Bunce.

GlaxoSmithKline (USA), Dr Thomas Leonard.

Health Protection Agency (Porton Down), Dr Keith Foster.

GlaxoSmithKline (UK), Dr Malcolm Johnson.

GlaxoSmithKline (USA), Dr Rupert Vessey.

Fellowships

Institute of Biology, Fellow.

Guest lectures

Airway mucus hypersecretion: targeting intracellular mechanisms for pharmacotherapy. XXXIII Congreso Annual, Sociedad de Farmacologia de Chile, Olmue, V Region, Chile. 2011.

Novel pharmacotherapeutic targets for asthma and COPD. Simposio Internacional, Facultad de Medicina, Instituto de Ciencias Biomedicas, Santiago, Chile. 2011.

Small airways structure and function. Simposio Internacional, Facultad de Medicina, Instituto de Ciencias Biomedicas, Santiago, Chile. 2011.

Airway mucus secretion and hypersecretion. Simposio Internacional, Facultad de Medicina, Instituto de Ciencias Biomedicas, Santiago, Chile. 2011.

Airway mucus and mucin genes in COPD. Hot Issues in Chronic Obstructive Pulmonary Disease – Update. Chang Gung Memorial Hospital Medical School, Taipei, Taiwan. 2011.

Future therapeutic targets for respiratory disease. 5th Annual Drug Delivery Systems, BSG Conference Centre, London. 2010.

Role of mucin in asthma pathogenesis. XXVIII Congress of the European Academy of Allergy and Clinical Immunology (EAACI 2009), Warsaw, Poland. 2009.

Muco-inhibitory drugs for airway mucus hypersecretion. International Society for Aerosols in Medicine, 17th Congress, Monterey, USA. 2009.

Targets for the future. Academy of Pharmaceutical Sciences: ‘APS Inhalation 2009’, Nottingham Conference Centre, Nottingham. 2009.

Mucoactive agents for mucus hypersecretory airway diseases. Gordon Research Conference: ‘Cilia, Mucus & Mucociliary Interactions’, Lucca, Italy. 2009.

Re-targeted Botox for chronic bronchitis. Infection, Inflammation & Repair Seminar Series, University of Southampton, Southampton. 2009.

Novel targets in mucus hypersecretion and modifying agents. COPD & Asthma: State of the Art, Management Forum, London. 2009.

Inhibition of airway mucus hypersecretion: Botox for the lungs?. Respiratory Research Group Seminar Series 2009, Wythenshawe Hospital, University of Manchester, Manchester. 2009.

Botox for the lungs?. Drug Delivery to the Lungs 19 (DDL19), The Aerosol Society, Edinburgh, Scotland. 2008.

New therapies to target MCC/CC in chronic bronchitis and asthma. ISAM/UNC Focus Symposium/ Workshop: ‘Mucociliary/Cough Clearance as a Biomarker for Therapeutic Development’, Research Triangle Park,, North Carolina, USA. ‘. 2008.

Mucus hypersecretion and modifying agents. The Management of Chronic Obstructive Pulmonary Disease and Asthma, Management Forum, London. 2008.

Inhibition of airway mucus hypersecretion. International Centre for Advanced Respiratory Medicine (CIMERA), Mallorca, Spain. 2008.

BoTox for the lungs?. Institute of Clinical Science, The Queen’s University of Belfast, Belfast, Northern Ireland. 2007.

Mucolytics and mucokinetics: acetylcysteine, Dornase, hyperosmolar aerosols and surfactant. 39th Journal Respiratory Care Conference: ‘Airway Clearance: Physiology, Pharmacology, Techniques and Practice’, Cancun, Mexico. 2007.

Physiology of mucus secretion. 39th Journal Respiratory Care Conference: ‘Airway Clearance: Physiology, Pharmacology, Techniques and Practice’, Cancun, Mexico. 2007.

Function of goblet cells in mucus secretion. Gordon Research Conference: ‘Cilia, Mucus & Mucociliary Interactions’, Ventura Beach, California, USA. 2007.

Retargeted botulinum endopeptidases inhibit airway mucus secretion: tox blocks snot. Biological Sciences Seminar Series, AstraZeneca, Lund, Sweden. 2007.

Mucus hypersecretion and modifying agents. The Management of Chronic Obstructive Pulmonary Disease and Asthma, Management Forum, London. 2006.

Inhibition of airway mucus secretion in asthm. XXV Congress of the European Academy of Allergology and Clinical Immunology (EAACI), Vienna. 2006.

Botulism for the lungs: inhibition of airway mucus secretion. Department of Infection, Immunity and Inflammation, University of Leicester, Leicester. 2005.

Mucus hypersecretion and modifying agents. COPD: Chronic Obstructive Pulmonary Disease, Management Forum, London. 2005.

Airway mucus hypersecretion: rationales for pharmacotherapy. Second Shanghai International Symposium on Respiratory Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. 2005.

Mucus hypersecretion in COPD. Department of Academic Respiratory Medicine, St. Bartholomew’s Hospital, london. 2005.

Targeting mucus production in lung disease. British Thoracic Society, Winter Meeting, London. 2004.

Airway mucus hypersecretion: basic mechanisms and rationales for novel therapy. Heatherwood and Wexham NHS Trust Medical Academic Half Day, Heatherwood Hospital, Ascot. 2004.

Mucus hypersecretion and modifying agents. Annual Conference on COPD, Management Forum, London. 2004.

Airway mucus hypersecretion: new pharmacotherapy in asthma and COPD. Centre for Respiratory Research, The Rayne Institute, University College London, London. 2004.

Mucus regulation and treatment. The Breathing Club: All Change in COPD, Chantilly, France. 2004.

Mucoregulators. COPD: The Important Questions III. Therapeutic Interventions Now and in the Future, Marbella, Spain. 2004.

Airway mucus hypersecretion: models and pharmacotherapeutics. Oxagen Limited, Oxford. 2004.

Airway mucus secretion: stimulation and rational approaches to inhibition of hypersecretion. Centre for Applied Microbiological Research, Porton Down, Wiltshire. 2003.

Mucus hypersecretion in COPD: pathophysiology and novel treatments. 6th Annual Conference on COPD, Management Forum, London. 2003.

Regulation of airway mucin secretion: stimulation and inhibition in experimental models and human disease. British Association for Lung Research Symposium on Airway Epithelial Defence Mechanisms, University of Brighton. 2003.

Neuronal control of airway mucus secretion. British Society for Allergy and Clinical Immunology, East Midlands Conference Centre, Nottingham. 2003.

Airway mucus hypersecretion: basic mechanisms and novel pharmacotherapy (Molecular Biology of the Cell Forum). University of Sunderland, Sunderland. 2003.

2002 International Meeting of the Interest Group for Cilia, Mucus and Mucociliary Interactions, 'Airway mucus hypersecretion and considerations for rational novel therapy.'. Miami Beach, USA. 2002.

COPD 3, International Convention Centre. 'Mucus regulation.'. Birmingham, UK. 2002.

National Clinical Coding Conference. 'Mucous hypersecrtetion in asthma and COPD.'. London, UK. 2002.

British Society for Allergy & Clinical Immunology: 'Neuronal Control of airway mucus secretion'. East Midlands Conference Centre, Nottingham, UK. 2003.

British Association for Lung Research: 'Regulation of airway mucin secretion: stimulation and inhibition in expermental models and human disease'. University of Brighton, UK. 2003.

6th Annual Conference on COPD: 'Mucus hypersecretion in COPD: pathophysiology and novel treatments'. Management Forum, London, UK. 2003.

COPD: The Important Questions III: 'Mucoregulators'. Marbella, Spain. 2004.

The Breathing Club: All Change in COPD: ' Mucus regulation and treatment'. Chantilly, France. 2004.

'Airway mucosa: secretory cells, mucus and mucin genes'. The XXth Congress of the European Acadamy of Allergology and Clinical Immunology, Berlin, Germany. 2001.

'Mucus hypersecretion in asthma and COPD: pathophysiology and models'. Roche Bioscience, Palo Alto, USA. 2001.

'Mucin gene expression in airway inflammation'. The Rayne Institute, University College London. 2001.

Airway mucin gene expression: pathophysiology and models'. Department of Cell and Molecular Biology, University of Lund, Sweden. 2001.

'Mucus hypersecretion in asthma and COPD: pathophysiology, models and treatment'. Merck Frosst Canada, Quebec, Canada. 2002.

'Airway mucus hypersecretion: models and therapies'. AstraZeneca, Charnwood, Loughborough. 2003.

'Airway secretions'. The Triangle of Asthma Management, Imperial College London. 2003.

'Airway mucus hypersecretion: basic mechanisms and novel pharmacotherapy'. Molecular Biology of the Cell Forum, University of Sunderland. 2003.

'Airway mucus secretion: stimulation and rational approaches to inhibition of hypersecretion'. Centre for Applied Microbiological Research, Porton Down, Salisbury. 2003.

'Airway mucus hypersecretion: models and pharmacotherapies'. Oxagen Limited, Oxford. 2004.

'Mucus regulation and treatment in asthma, COPD and allergic rhinitis'. Asthma and Allergy Research group, NHLI, Imperial College London. 2004.

'Airway mucus hypersecretion: new pharmacotherapy in asthma and COPD'. The Rayne Institute, University College London. 2004.

'Mucus hypersecretion and modyfying agents'. Annual Conference on COPD, Management Forum, London. 2004.

'Airway mucus hypersecretio: basic mechanisms and rationales for novel therapy'. Heatherwood and Wexham NHS Trust Medical half Day, Heatherwood Hospital, Ascot. 2004.

'Targeting mucus production in lung disease'. British Thoracic Society Winter Meeting, London. 2004.