Dr Fang-Ping Huang

Publications


Journals

  • Sun J; Li R; Guo J; Jia Y; Sun X; Liu Y; Li Y; Huang F; et alLu L; Li Z. (9 Jan 2012). A superior molecularly altered influenza virus haemagglutinin (HA) peptide HA308-317 inhibits CIA by inducing CD4(+) regulatory T cell expansion. Arthritis Rheum. DOI.
  • Ling GS; Cook HT; Botto M; Lau YL; Huang FP. (Oct 2011). An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells. Rheumatology (Oxford). 50:1773-1784. DOI.
  • Huang FP; Chen YX; To KW. (Jan 2011). Guiding the “Misguided” - Functional Conditioning of Dendritic Cells for the DC-based Immunotherapy against Tumours. European Journal of Immunology. 41:18-25. DOI.
  • Mok MY; Huang FP; Ip WK; Lo Y; Wong FY; Chan EYT; Lam KF; Xu D. (1 Mar 2010). Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus. RHEUMATOLOGY. 49:520-527. Author weblink DOI.
  • Xie Y; Fang J; Chen J; Huang FP; Cao B; Tam PK; Ren Y. (2009). A novel function for dendritic cell: clearance of VEGF via VEGF receptor-1. Biochem Biophys Res Commun. 380:243-248. DOI.
  • Yang CH; Tian L; Ling GS; Trendell-Smith NJ; Ma L; Lo CK; Stott DI; Liew FY; et alHuang FP. (Jun 2008). Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15. Eur J Immunol. 38:1664-1676. DOI.
  • Sun Q; Kong CT; Huang FP; Chan LC. (Jan 2008). Aberrant dendritic cell differentiation initiated by the Mll-Een fusion gene does not require leukemic transformation. J Leukoc Biol. 83:173-180. DOI.
  • Chen YX; Man K; Ling GS; Chen Y; Sun BS; Cheng Q; Wong OH; Lo CK; et alNg IO; Chan LC; Lau GK; Lin CLS; Huang F; Huang FP. Boss JM (ed). (1 Nov 2007). A crucial role for dendritic cell (DC) IL-10 in inhibiting successful DC-Based immunotherapy: Superior antitumor immunity against hepatocellular carcinoma evoked by DC devoid of IL-10. J IMMUNOL. 179:6009-6015. Publisher weblink.
  • Chen Y; Chan VS; Zheng B; Chan KY; Xu X; To LY; Huang FP; Khoo US; et alLin CL. (29 Oct 2007). A novel subset of putative stem/progenitor CD34+Oct-4+ cells is the major target for SARS coronavirus in human lung. J Exp Med. 204:2529-2536. DOI.
  • Chan KY; Ching JC; Xu MS; Cheung AN; Yip SP; Yam LY; Lai ST; Chu CM; et alWong AT; Song YQ; Huang FP; Liu W; Chung PH; Leung GM; Chow EY; Chan EY; Chan JC; Ngan HY; Tam P; Chan LC; Sham P; Chan VS; Peiris M; Lin SC; Khoo US. (15 Jul 2007). Association of ICAM3 genetic variant with severe acute respiratory syndrome. J Infect Dis. 196:271-280. Publisher weblink.
  • Ma L; Chan KW; Trendell-Smith NJ; Wu A; Tian L; Lam AC; Chan AK; Lo CK; et alChik S; Ko KH; To CK; Kam SK; Li XS; Yang CH; Leung SY; Ng MH; Stott DI; MacPherson GG; Huang FP. (Nov 2005). Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains. Eur J Immunol. 35:3364-3375. DOI.
  • Wong OH; Huang FP; Chiang AK. (Sep 2005). Differential responses of cord and adult blood-derived dendritic cells to dying cells. Immunology. 116:13-20. DOI.
  • MacPherson GG; Milling S; Yrlid U; Cousins L; Turnbull E; Huang FP. (2004). Uptake of antigens from the intestine by dendritic cells. Ann N Y Acad Sci. 1029:75-82.
  • Huang FP; MacPherson GG. (2004). Dendritic cells and oral transmission of prion diseases. Adv Drug Deliv Rev. 56:901-913.
  • Huang F; Farquhar CF; Mabbott NA; Bruce ME; MacPherson GG. (Jan 2002). Migrating intestinal dendritic cells transport PrP(Sc) from the gut. J Gen Virol. 83:267-271. Publisher weblink.
  • Esfandiari E; McInnes I; Lindop G; Huang F; Field M; Liew FY. (1 Nov 2001). A proinflammatory role of IL-18 in the development of spontaneous autoimmune disease. J Immunol. 167:5338-5347. Publisher weblink.
  • Huang FP; MacPherson GG. (2001). Continuing education of the immune system -dendritic cells, immune regulation and tolerance. Curr Mol Med. 1:457-468.
  • Huang FP; Platt N; Wykes M; Major JR; Powell TJ; Jenkins CD; MacPherson GG. (2000). A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J Exp Med. 191:435-444.
  • Huggins ML; Huang FP; Xu D; Lindop G; Stott DI. (1999). Modulation of autoimmune disease in the MRL-lpr/lpr mouse by IL-2 and TGF-beta1 gene therapy using attenuated Salmonella typhimurium as gene carrier. Lupus. 8:29-38.
  • Huang FP; Niedbala W; Wei XQ; Xu D; Feng GJ; Robinson JH; Lam C; Liew FY. (1998). Nitric oxide regulates Th1 cell development through the inhibition of IL-12 synthesis by macrophages. Eur J Immunol. 28:4062-4070.
  • Huang FP; Xu D; Esfandiari EO; Sands W; Wei XQ; Liew FY. (1998). Mice defective in Fas are highly susceptible to Leishmania major infection despite elevated IL-12 synthesis, strong Th1 responses, and enhanced nitric oxide production. J Immunol. 160:4143-4147.
  • MacLean A; Wei XQ; Huang FP; Al-Alem UA; Chan WL; Liew FY. (1998). Mice lacking inducible nitric-oxide synthase are more susceptible to herpes simplex virus infection despite enhanced Th1 cell responses. J Gen Virol. 79:825-830.
  • Casey JJ; Wei XQ; Orr DJ; Gracie JA; Huang FP; Bolton EM; Liew FY; Bradley JA. (1997). Skin allograft rejection in mice lacking inducible nitric oxide synthase. Transplantation. 64:589-593.
  • Huggins ML; Huang FP; Xu D; Lindop G; Stott DI. (1997). Modulation of the autoimmune response in lupus mice by oral administration of attenuated Salmonella typhimurium expressing the IL-2 and TGF-beta genes. Ann N Y Acad Sci. 815:499-502.
  • McInnes IB; Leung BP; Field M; Wei XQ; Huang FP; Sturrock RD; Kinninmonth A; Weidner J; et alMumford R; Liew FY. (1996). Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. J Exp Med. 184(4):1519-24.:1519-1524.
  • Huang FP; Feng GJ; Lindop G; Stott DI; Liew FY. (1996). The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice. J Exp Med. 183:1447-1459.
  • McInnes IB; al-Mughales J; Field M; Leung BP; Huang FP; Dixon R; Sturrock RD; Wilkinson PC; et alLiew FY. (1996). The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis. Nat Med. 2:175-182.
  • Huang FP; Stott DI. (1995). Dual inhibitory and stimulatory activities in serum from SLE patients and lupus mice that regulate the proliferation of an IL-2-dependent T cell line. Lupus. 4:297-303.
  • Wei XQ; Charles IG; Smith A; Ure J; Feng GJ; Huang FP; Xu D; Muller W; et alMoncada S. (1995). Altered immune responses in mice lacking inducible nitric oxide synthase. Nature. 375:408-411.
  • Huang FP; Stott DI. (1993). Restoration of an early, progressive defect in responsiveness to T-cell activation in lupus mice by exogenous IL-2. Autoimmunity. 15:19-29.

Books

  • d’Annunzio G; Russo C; Tallone R; Lorini R; Sarı E; Karaoglu A; Yeşilkaya E. Huang FP (ed). Autoimmune Disorders - Current Concepts and Advances from Bedside to Mechanistic Insights. 1-614. InTech (Nov 2011). Publisher weblink.

Chapters in books

  • Sattler S; van der Vlug LEPM; Hussaarts L; Smits HH; Huang FP. Regulatory B cells - implications in autoimmune and allergic disorders. In Immune System. Kanwar J (ed). Intech (2011). Publisher weblink.
  • Huang FP; Sattler S. Regulatory T cell deficiency in systemic autoimmune disorders – the causal relationship and underlying immunological mechanisms. In Autoimmune Disorders -Pathogenic Aspects. 1:111-126. Mavragani CP (ed). Intech (Oct 2011). Publisher weblink.
  • MacPherson GG; Huang FP; Liu LM. Intestinal Dendritic Cells. In Dendritic Cells: Biology and Clinical Applications. 2nd:325-336. Lotze MT (ed); Thomson AW (ed). Harcourt International Academic Press (Aug 2001).
  • MacPherson GG; Wykes M; Huang FP; Jenkins CD. Isolation of dendritic cells from rat lymph and spleen. In Methods in Molecular Medicine: Dendritic Cell Protocols. 29-41. Robinson SP (ed). Humana Press (2001).

Patents

  • ANTI-TUMOR VACCINES DELIVERED BY DENDRITIC CELLS DEVOID OF INTERLEUKIN-10. Patent number: 20090010948 (US). Application: 11/957,146. Filed: 14 Dec 2007. Published: 8 Jan 2009. Publisher weblink.
  • ANTI-TUMOR VACCINES DELIVERED BY DENDRITIC CELLS DEVOID OF INTERLEUKIN-10. Patent number: WO/2008/071093 (PCT). Application: PCT/CN2007/003619. Filed: 17 Dec 2007. Published: 19 Jun 2008. Publisher weblink.
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