Dr Graeme M Birdsey

Publications


Journals

  • Dryden NH; Sperone A; Martin-Almedina S; Hannah RL; Birdsey GM; Khan ST; Layhadi JA; Mason JC; et alHaskard DO; Göttgens B; Randi AM. (6 Apr 2012). The Transcription Factor Erg Controls Endothelial Cell Quiescence by Repressing Activity of Nuclear Factor (NF)-κB p65. J Biol Chem. 287:12331-12342. DOI.
  • Birdsey GM; Dryden NH; Shah AV; Hannah R; Hall MD; Haskard DO; Parsons M; Mason JC; et alZvelebil M; Gottgens B; Ridley AJ; Randi AM. (19 Jan 2012). The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis. Blood. 119:894-903. DOI.
  • Garonna E; Botham KM; Birdsey GM; Randi AM; Gonzalez-Perez RR; Wheeler-Jones CP. (2011). Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells. PLoS One. 6:e18823. DOI.
  • Sperone A; Dryden NH; Birdsey GM; Madden L; Johns M; Evans PC; Mason JC; Haskard DO; et alBoyle JJ; Paleolog EM; Randi AM. (Jan 2011). The transcription factor Erg inhibits vascular inflammation by repressing NF-kappaB activation and proinflammatory gene expression in endothelial cells. Arterioscler Thromb Vasc Biol. 31:142-150. DOI.
  • McKinnon TA; Goode EC; Birdsey GM; Nowak AA; Chan AC; Lane DA; Laffan MA. (29 Jul 2010). Specific N-linked glycosylation sites modulate synthesis and secretion of von Willebrand factor. Blood. 116:640-648. DOI.
  • Hamdulay SS; Wang B; Birdsey GM; Ali F; Dumont O; Evans PC; Haskard DO; Wheeler-Jones CP; et alMason JC. (15 Apr 2010). Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. Free Radic Biol Med. 48:1013-1023. DOI.
  • Shovlin CL; Angus G; Manning RA; Okoli GN; Govani FS; Elderfield K; Birdsey GM; Mollet IG; et alLaffan MA; Mauri FA. (2010). Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension. PLoS One. 5:e9154. DOI.
  • Randi AM; Sperone A; Dryden NH; Birdsey GM. (1 Dec 2009). Regulation of angiogenesis by ETS transcription factors. BIOCHEMICAL SOCIETY TRANSACTIONS. 37:1248-1253. Author weblink DOI.
  • Birdsey GM; Dryden NH; Amsellem V; Gebhardt F; Sahnan K; Haskard DO; Dejana E; Mason JC; et alRandi AM. (1 Apr 2008). Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin. Blood. 111:3498-3506. DOI.
  • Huang MT; Mason JC; Birdsey GM; Amsellem V; Gerwin N; Haskard DO; Ridley AJ; Randi AM. (1 Sep 2005). Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis. Blood. 106:1636-1643. DOI.
  • Huber PA; Birdsey GM; Lumb MJ; Prowse DT; Perkins TJ; Knight DR; Danpure CJ. (22 Jul 2005). Peroxisomal import of human alanine:glyoxylate aminotransferase requires ancillary targeting information remote from its C terminus. J Biol Chem. 280:27111-27120. DOI.
  • Birdsey GM; Lewin J; Holbrook JD; Simpson VR; Cunningham AA; Danpure CJ. (22 Apr 2005). A comparative analysis of the evolutionary relationship between diet and enzyme targeting in bats, marsupials and other mammals. Proc Biol Sci. 272:833-840. DOI.
  • Birdsey GM; Lewin J; Cunningham AA; Bruford MW; Danpure CJ. (Apr 2004). Differential enzyme targeting as an evolutionary adaptation to herbivory in carnivora. Mol Biol Evol. 21:632-646. DOI.
  • Smith CL; Birdsey GM; Anthony S; Arrigoni FI; Leiper JM; Vallance P. (5 Sep 2003). Dimethylarginine dimethylaminohydrolase activity modulates ADMA levels, VEGF expression, and cell phenotype. Biochem Biophys Res Commun. 308:984-989.
  • Lumb MJ; Birdsey GM; Danpure CJ. (15 Aug 2003). Correction of an enzyme trafficking defect in hereditary kidney stone disease in vitro. Biochem J. 374:79-87. DOI.
  • van der Giezen M; Birdsey GM; Horner DS; Lucocq J; Dyal PL; Benchimol M; Danpure CJ; Embley TM. (Jul 2003). Fungal hydrogenosomes contain mitochondrial heat-shock proteins. Mol Biol Evol. 20:1051-1061. DOI.
  • Danpure CJ; Lumb MJ; Birdsey GM; Zhang X. (11 Apr 2003). Alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting in human hereditary kidney stone disease. Biochim Biophys Acta. 1647:70-75.
  • Knott TG; Birdsey GM; Sinclair KE; Gallagher IM; Purdue PE; Danpure CJ. (1 Dec 2000). The peroxisomal targeting sequence type 1 receptor, Pex5p, and the peroxisomal import efficiency of alanine:glyoxylate aminotransferase. Biochem J. 352 Pt 2:409-418.
  • Achan V; Tran C; Maria JS; Birdsey GM; Whitley GSJ; Leiper JM; Vallance PJ. (31 Oct 2000). All-trans-retinoic acid increases nitric oxide synthesis by endothelial cells: A role for the induction of dimethylarginine dimethylaminohydrolase. CIRCULATION. 102:17-17. Author weblink.
  • Holbrook JD; Birdsey GM; Yang Z; Bruford MW; Danpure CJ. (Mar 2000). Molecular adaptation of alanine:glyoxylate aminotransferase targeting in primates. Mol Biol Evol. 17:387-400.
  • Birdsey GM; Leiper JM; Vallance P. (Jan 2000). Intracellular localization of dimethylarginine dimethylaminohydrolase overexpressed in an endothelial cell line. Acta Physiol Scand. 168:73-79.
  • Birdsey GM; Danpure CJ. (1 Apr 1998). Evolution of alanine:glyoxylate aminotransferase intracellular targeting: structural and functional analysis of the guinea pig gene. Biochem J. 331 ( Pt 1):49-60.
  • Leiper JM; Birdsey GM; Oatey PB. (Nov 1995). Peroxisomes proliferate. Trends Cell Biol. 5:435-437.
  • Danpure CJ; Birdsey GM; Rumsby G; Lumb MJ; Purdue PE; Allsop J. (Jul 1994). Molecular characterization and clinical use of a polymorphic tandem repeat in an intron of the human alanine:glyoxylate aminotransferase gene. Hum Genet. 94:55-64.

Conferences

  • Sperone A; Dryden N; Birdsey GM; Madden LE; Evans P; Mason JC; Boyle J; Paleolog E; et alHaskard DO; Randi AM. The transcription factor Erg represses ICAM-1 expression and vascular inflammation. 213:E17-E17. ELSEVIER IRELAND LTD (1 Nov 2010). Author weblink DOI.
  • Sperone A; Birdsey GM; Dryden N; Madden LE; Evans P; Mason JC; Paleolog E; Haskard DO; et alRandi AM. The Transcription Factor Erg Represses ICAM-1 Expression and Vascular Inflammation. Scientific Sessions on Arteriosclerosis, Thrombosis and Vascular Biology, 8 Apr 2010 - 10 Apr 2010. 30:E228-E228. LIPPINCOTT WILLIAMS & WILKINS (1 Nov 2010). Author weblink.
  • Sperone A; Birdsey GM; Dryden N; Evans P; Boyle J; Haskard DO; Mason JC; Randi AM. THE TRANSCRIPTION FACTOR ERG PREVENTS VASCULAR INFLAMMATION BY REPRESSING ICAM-1 EXPRESSION. Spring Meeting of the British-Society-for-Cardiovascular-Research, 2 Apr 2009 - 4 Apr 2009. 95. B M J PUBLISHING GROUP (15 Nov 2009). Author weblink DOI.
  • Birdsey GM; Dryden NH; Arnsellem V; Gebhardt F; Haskard DO; Dejana E; Mason JC; Randi AM. The transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin. Spring Meeting of the British-Atherosclerosis-Society on Angiogenesis and Atherosclerosis, 3 Apr 2008 - 4 Apr 2008. 199:465-465. ELSEVIER IRELAND LTD (1 Aug 2008). Author weblink DOI.
  • Birdsey GM; Amsellem V; Mason JC; Gebhardt F; Taylor KM; Haskard DO; Randi AM. The transcription factor ERG regulates angiogenesis and apoptosis. Joint Autumn Meeting of the British-Society-for-Cardiovascular-Research/British-Atherosclerosis-Society, 21 Sep 2006 - 22 Sep 2006. 93. B M J PUBLISHING GROUP (1 Feb 2007). Author weblink.
  • Garonna E; Birdsey GM; Botham KM; Randi AM; Wheeler-Jones CPD. Leptin-memated proliferation and migration of human endothelial depends on cyclooxygenase-2 [COX-2] activity and requires activation of vascular endothelial growth factor receptor 2 [VEGFR2]. 24th Conference of the European-Society-for-Microcirculation, 30 Aug 2006 - 2 Sep 2006. 43:58-58. KARGER (1 Jan 2006). Author weblink.
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