Professor Glenda E Gillies

Publications


Journals

  • McArthur S; Robinson IC; Gillies GE. (2010). Novel Ontogenetic Patterns of Sexual Differentiation in Arcuate Nucleus GHRH Neurons revealed in GHRH-Enhanced Green Fluorescent Protein Transgenic Mice. Endocrinology.
  • Gillies GE; McArthur S. (2010). Estrogen actions in the brain and the bases for differential actions in men and women: a case for sex-specific medicines. Pharmacological Reviews. 62:155-198.
  • McArthur S; Cristante E; Paterno M; Christian H; Roncaroli F; Gillies GE; Solito E. (15 Nov 2010). Annexin A1: a central player in the anti-inflammatory and neuroprotective role of microglia. J Immunol. 185:6317-6328. DOI.
  • Gillies GE; McArthur S. (Jan 2010). Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson's disease: A contribution to sex-specific neuroprotection by estrogens. Horm Behav. 57:23-34. DOI.
  • Dexter D; Allen R; Gillies G; Buckingham J. (15 Sep 2010). Stress is a Predisposing Factor for Parkinson's Disease in Males but Not Females. MOVEMENT DISORDERS. 25:S619-S619.
  • McArthur S; Prasongchean W; Gillies G; Solito E. (1 Aug 2008). A critical role for the anti-inflammatory protein annexin A1 in microglial phagocytosis. FUNDAMENTAL & CLINICAL PHARMACOLOGY. 22:23-23. Author weblink.
  • Solito E; McArthur S; Christian H; Gavins F; Buckingham JC; Gillies GE. (Mar 2008). Annexin A1 in the brain--undiscovered roles?. Trends Pharmacol Sci. 29:135-142. DOI.
  • McArthur S; McHale E; Gillies GE. (1 Jul 2007). The size and distribution of midbrain dopaminergic populations are permanently altered by perinatal glucocorticoid exposure in a sex- region- and time-specific manner. NEUROPSYCHOPHARMACOLOGY. 32:1462-1476. Author weblink DOI.
  • McArthur S; Murray HE; Dhankot A; Dexter DT; Gillies GE. (Feb 2007). Striatal susceptibility to a dopaminergic neurotoxin is independent of sex hormone effects on cell survival and DAT expression but is exacerbated by central aromatase inhibition. J Neurochem. 100:678-692. DOI.
  • Warne JP; John CD; Christian HC; Morris JF; Flower RJ; Sugden D; Solito E; Gillies GE; et alBuckingham JC. (Dec 2006). Gene deletion reveals roles for annexin A1 in the regulation of lipolysis and IL-6 release in epididymal adipose tissue. Am J Physiol Endocrinol Metab. 291:E1264-E1273. DOI.
  • McArthur S; Siddique ZL; Christian HC; Capone G; Theogaraj E; John CD; Smith SF; Morris JF; et alBuckingham JC; Gillies GE. (Apr 2006). Perinatal glucocorticoid treatment disrupts the hypothalamo-lactotroph axis in adult female, but not male, rats. Endocrinology. 147:1904-1915. DOI.
  • McArthur S; McHale E; Dalley JW; Buckingham JC; Gillies GE. (Aug 2005). Altered mesencephalic dopaminergic populations in adulthood as a consequence of brief perinatal glucocorticoid exposure. J Neuroendocrinol. 17:475-482. DOI.
  • Gillies GE; Murray HE; Dexter D; McArthur S. (Jul 2004). Sex dimorphisms in the neuroprotective effects of estrogen in an animal model of Parkinson's disease. Pharmacol Biochem Behav. 78:513-522. DOI.
  • Datla KP; Murray HE; Pillai AV; Gillies GE; Dexter DT. (20 Jan 2003). Differences in dopaminergic neuroprotective effects of estrogen during estrous cycle. Neuroreport. 14:47-50. DOI.
  • Murray HE; Pillai AV; McArthur SR; Razvi N; Datla KP; Dexter DT; Gillies GE. (2003). Dose- and sex-dependent effects of the neurotoxin 6-hydroxydopamine on the nigrostriatal dopaminergic pathway of adult rats: differential actions of estrogen in males and females. Neuroscience. 116:213-222.
  • Pannell C; Simonian SX; Gillies GE; Luscher B; Herbison AE. (Aug 2002). Hypothalamic somatostatin and growth hormone-releasing hormone mRNA expression depend upon GABA(A) receptor expression in the developing mouse. Neuroendocrinology. 76:93-98.
  • Murray HE; McArthur SR; Dexter DT; Gillies GE. (1 Mar 2002). Sex difference in the effects of 6-hydroxydopamine lesions in the nigrostriatal dopaminergic pathway of adult rats and sexually dimorphic actions of 17 beta-estradiol. BRITISH JOURNAL OF PHARMACOLOGY. 135.
  • Lamfon H; Gillies G; Theogaraj E; John C; Smith SF; Buckingham JC. (1 Mar 2002). Effects of neonatal dexamethasone, treatment on thymic NOS-2 expression in the adult rat. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Gillies G; Murray H; Dexter D. (1 Mar 2002). Organizational and activational effects of sex steroid hormones in the brain: Implications for growth, neuroprotection and disease susceptibility. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Murray HE; Rantle CM; Gillies GE. (1 Jun 2000). Differential ontogeny and sexual dimorphism of gamma-aminobutyric acid content and secretion in selected nuclei of the rat hypothalamus. JOURNAL OF PHYSIOLOGY-LONDON. 525:54P-55P. Author weblink.
  • Murray HE; Rantle CM; Simonian SX; DonCarlos LL; Herbison AE; Gillies GE. (Dec 1999). Sexually dimorphic ontogeny of GABAergic influences on periventricular somatostatin neurons. Neuroendocrinology. 70:384-391.
  • Christian M; Gillies G. (Mar 1999). Developing hypothalamic dopaminergic neurones as potential targets for environmental estrogens. J Endocrinol. 160:R1-R6.
  • Christian M; Gillies G. (1 Mar 1999). Effects of beta 17 beta-oestradiol and environmental oestrogens on developing rat hypothalamic dopaminergic neurones in culture. BRITISH JOURNAL OF PHARMACOLOGY. 126:U76-U76. Author weblink.
  • Murray HE; Simonian SX; Herbison AE; Gillies GE. (Jan 1999). Correlation of hypothalamic somatostatin mRNA expression and peptide content with secretion: sexual dimorphism and differential regulation by gonadal factors. J Neuroendocrinol. 11:27-33.
  • Murray HE; Simonian SX; Herbison AE; Gillies GE. (Jan 1999). Ontogeny and sexual differentiation of somatostatin biosynthesis and secretion in the hypothalamic periventricular-median eminence pathway. J Neuroendocrinol. 11:35-42.
  • Simonian SX; Murray HE; Gillies GE; Herbison AE. (1 Mar 1998). Estrogen-dependent ontogeny of sex differences in somatostatin neurons of the hypothalamic periventricular nucleus. ENDOCRINOLOGY. 139:1420-1428. Author weblink DOI.
  • Murray HE; Gillies GE. (Apr 1997). Differential effects of neuroactive steroids on somatostatin and dopamine secretion from primary hypothalamic cell cultures. J Neuroendocrinol. 9:287-295.
  • Gillies G. (Mar 1997). Somatostatin: the neuroendocrine story. Trends Pharmacol Sci. 18:87-95.
  • MURRAY HE; GILLIES GE. (1 Apr 1995). NEGATIVE ALLOSTERIC MODULATION AT GABA RECEPTORS AND SOMATOSTATIN SECRETION. BRITISH JOURNAL OF PHARMACOLOGY. 114:P301-P301.
  • Gillies GE; Buckingham JC. (1995). The application of in vitro models of hypothalamic function in toxicity testing. Methods Mol Biol. 43:95-107. DOI.
  • Gillies GE; Buckingham JC. (1995). The application of in vitro models of anterior pituitary function in toxicity testing. Methods Mol Biol. 43:81-93. DOI.
  • DAVIDSON K; GILLIES GE. (1 May 1994). NOVEL ACTIONS OF A BENZODIAZEPINE AND A BARBITURATE ON SOMATOSTATIN RELEASE FROM THE PERINATAL HYPOTHALAMUS IN CULTURE. BRITISH JOURNAL OF PHARMACOLOGY. 112:U135-U135. Author weblink.
  • HOFFMAN S; MURRAY HE; RANTLE C; GILLIES GE. (1 May 1994). INVESTIGATIONS ON THE UPTAKE AND RELEASE OF [H-3] GABA FROM PERINATAL HYPOTHALAMUS IN PRIMARY-CELL CULTURE. BRITISH JOURNAL OF PHARMACOLOGY. 112:U135-U135. Author weblink.
  • Currie IS; Gillies GE; Brooks AN. (1994). Modulation of arginine vasopressin secretion from cultured ovine hypothalamic cells by glucocorticoids and opioid peptides. Neuroendocrinology 60, (1994), 360-366. 60:360-366.
  • MURRAY HE; GILLIES GE. (1 Dec 1993). INVESTIGATION OF THE ONTOGENIC PATTERNS OF RAT HYPOTHALAMIC DOPAMINERGIC NEURON MORPHOLOGY AND FUNCTION IN-VITRO. JOURNAL OF ENDOCRINOLOGY. 139:403-&. Author weblink DOI.
  • Murray HE; Gillies GE. (Dec 1993). Investigation of the ontogenetic patterns of rat hypothalamic dopaminergic neurone morphology and function in vitro. J Endocrinol. 139:403-414.
  • Davidson K; Gillies GE. (8 Oct 1993). Neuronal vs. glial somatostatin in the hypothalamus: a cell culture study of the ontogenesis of cellular location, content and release. Brain Res. 624:75-84.
  • Hannah M; Jackson S; Gillies GE; Lowry PJ. (1993). Met-enkephalin secretion from mixed cultures of hypothalamic neurons and astrocytes. Neuroendocrinology. 57:884-891.
  • Gillies GE; Davidson K. (1992). GABAergic influences on somatostatin secretion from hypothalamic neurones cultured in defined medium. Neuroendocrinology. 55:248-256.
  • GILLIES GE; GULDENAAR S; DAVIDSON K. (1 Jan 1991). INTERACTIONS BETWEEN GABAERGIC AND SOMATOSTATIN-PRODUCING CELLS IN CULTURES OF FETAL-RAT HYPOTHALAMI. JOURNAL OF PHYSIOLOGY-LONDON. 438:P52-P52. Author weblink.
  • Tsagarakis S; Gillies GE; Rees LH; Besser M; Grossman A. (1989). Interleukin-1 directly stimulates the release of corticotrophin releasing factor from the rat hypothalamus in vitro. Endocrinology. 123:1962-1969.
  • Clarke MJO; Gillies GE. (1988). Comparison of peptide release from fetal rat hypothalamic neurones cultured in defined medium and serum-containing medium. Journal of Endocrinology. 116:349-356.
  • Clarke MJO; Lowry PJ; Gillies GE. (1987). Assessment of corticotropin releasing factor, vasopressin and somatostatin secretion by fetal hypothalamic neurones in culture. Neuroendocrinology. 46:147-154.
  • Lowry PJ; Estivarez FE; Gillies GE; Kruseman AC; Linton EA. (1986). CRF: its regulation of ACTH and pro-opiomelanocortin peptide release and its extra hypothalamic occurrence. Acta Endocrinol Suppl (Copenh). 276:56-62.
  • Gillies GE; Grossman A. (1985). The CRFs and their control: Chemistry, Physiology and clinical implications. Clinics in Endocrinology and Metabolism. 14:821-845.
  • Gillies GE; Puri A; Hodgkinson S; Lowry PJ. (1984). Involvement of rat CRF-41 and vasopressin in ACTH releasing activity from superfused rat hypothalami in vitro. Journal of Endocrinology. 103:25-29.
  • Gillies GE; Puri A; Linton EA; Lowry PJ. (1984). Comparative chromatography of hypothalamic corticotropin-releasing factors. Neuroendocrinology. 36:17-24.
  • Linton EA; Gillies GE; Lowry PJ. (1983). Ovine CRF and vasopressin: Antibody-quenching studies on hypothalamic extract of normal and Brattleboro rat. Endocrinology. 113:1878-1884.
  • Ratter SJ; Gillies GE; Hope J; Hale C; Grossman A; Gaillard R; Cook D; Edwards CRW; et alRees LH. (1983). Pro-opiocortin related peptides in human pituitary and ectopic ACTH secreting tumours. Clinical Endocrinology. 18:211-218.
  • Gillies GE; Linton EA; Lowry PJ. (1982). Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin. Nature. 299:355-356.
  • Forda SR; Gillies GE; Kelly JS; Micklem KJ; Pasternak CA. (1982). Acute membrane response to viral action. Neuroscience Letts. 29:237-242.
  • Batt RAL; Everard DM; Gillies GE; Wilkinson M; Wilson CA; Yeo TA. (1982). Investigations into the hypogonadism of the obese mouse (genotype ob/ob). Journal of Reproduction and Fertility. 64:364-371.
  • Ratter SJ; McLoughlin L; Gillies G; Clement-Jones V; Hope J; Rees LH. (1981). Pars intermedia peptides: studies in adult humans. Ciba Foundation Symposium. 81:224-243.
  • Gaillard RC; Grossman A; Gillies GE; Rees LH; Besser GM. (1981). Angiotensin II stimulates the release of ACTH from dispersed rat anterior pituitary cells. Clinical Endocrinology. 15:573-578.
  • Estivariz FE; Gillies GE; Lowry PJ. (1981). Biosynthesis and control of secretion of corticotrophic, lipotrohic and melanotrophic peptides. Pharmacol. Ther. 13:61-67.
  • Gillies GE; Ratter S; Grossman A; Gaiilard R; Lowry PJ; Besser GM. (1980). ACTH, LPH and ß-endorphin secretion from perfused isolated human pituitary tumour cells in vitro. Hormone Research. 13:280-290.
  • Lowry PJ; Sykes JEC; Gillies GE. (1980). Studies on corticotropin releasing factors using the perfused isolated pituitary cell column. Advanced Biochem Pharmacol. 22:119-129.
  • Gillies GE; Ratter S; Grossman A; Gaillard R; Lowry PJ; Besser GM; Rees LH. (1980). Secretion of ACTH, LPH and Beta-Endorphin from human pituitary tumours in vitro. Clinical Endocirnology. 13:179-205.
  • Gillies GE; Lowry PJ. (1979). Corticotrophin releasing factor may be modulated vasopressin. Nature. 278:463-464.
  • Gillies GE; Lowry PJ. (1980). Reply to Pearlmutter et al. "Is corticotrophin releasing factor modulated vasopressin?". Nature. 283:598.
  • Mashiter K; Adams EF; Gillies GE; van Noorden S; Ratter S. (1980). ACTH and lipotropin secretion by dispersed cell cultures of human corticotropin adenoma: Effects of hypothalamic extract, arginine vasopressin, hydrocortisone and serotonin. Journal of Clinical Endocrinology and Metabolism. 51:566-572.
  • Gillies GE; Lowry PJ. (1980). Corticotropin-releasing activity in extracts of the stalk median eminence of Brattleboro rats. Journal of Endocrinology. 84:65-73.
  • Gillies GE; van Wimersma Greidanus TB; Lowry PJ. (1978). Characterisation of rat stalk median eminence vasopressin and its involvement in adrenocorticotropin release. Endocrinology. 103:528-534.
  • Gillies GE; Lowry PJ. (1978). Perfused rat isolated anterior pituitary cell column as a bioassay for factor(s) controlling release of adrenocorticotropin: Validation of a technique. Endocrinology. 103:521-527.
  • Lowry PJ; Rees LH; Tomlin S; Gillies GE; Landon J. (1978). Chemical characterisation of ectopic ACTH purified from a malignant thymic carcinoid tumour. J. Clin. Endocrol and Metab. 43:831-835.

Conferences

  • Gillies G; McArthur S; McHale E. Sex dimorphisms in the 3D cytoarchitecture of the adult VTA and permanent alterations by glucocorticoid exposure in late gestation. 6th International Congress of Neuroendocrinology, 19 Jun 2006 - 22 Jun 2006. 27:95-96. ACADEMIC PRESS INC ELSEVIER SCIENCE (1 May 2006). Author weblink DOI.
  • Gillies GE; Davidson K; Murray HE; Christian MC. Gonadal steroids and hypothalamic neuronal development. Scientific Meeting of the Physiological-Society, 16 Apr 1996 - 18 Apr 1996. 494P:S10-S11. CAMBRIDGE UNIV PRESS (1 Jul 1996). Author weblink.
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