Professor Geoffrey L Smith FRS

Publications


Journals

  • Unterholzner L; Sumner RP; Baran M; Ren H; Mansur DS; Bourke NM; Randow F; Smith GL; et alBowie AG. (Sep 2011). Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7. PLoS Pathog. 7:e1002247. DOI.
  • Johnson BF; Kanatani Y; Fujii T; Saito T; Yokote H; Smith GL. (Oct 2011). Serological responses in humans to the smallpox vaccine LC16m8. J Gen Virol. 92:2405-2410. DOI.
  • Benfield CT; Mansur DS; McCoy LE; Ferguson BJ; Bahar MW; Oldring AP; Grimes JM; Stuart DI; et alGraham SC; Smith GL. (10 Jun 2011). Mapping the IkappaB kinase beta (IKKbeta)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKbeta-mediated activation of nuclear factor kappaB. J Biol Chem. 286:20727-20735. DOI.
  • Bahar MW; Graham SC; Chen RA; Cooray S; Smith GL; Stuart DI; Grimes JM. (Aug 2011). How vaccinia virus has evolved to subvert the host immune response. J Struct Biol. 175:127-134. DOI.
  • Salek-Ardakani S; Flynn R; Arens R; Yagita H; Smith GL; Borst J; Schoenberger SP; Croft M. (1 Jan 2011). The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice. JOURNAL OF CLINICAL INVESTIGATION. 121:296-307. DOI.
  • Smith GL; Davison N. (1 Jan 2010). Assessing the spectrum of biological risks. BULLETIN OF THE ATOMIC SCIENTISTS. 66:1-11. Author weblink DOI.
  • Doceul V; Breiman A; Hollinshead M; Smith GL. (Jun 2010). [Rapid cell-to-cell spread: a story of jumping viruses]. Med Sci (Paris). 26:574-576. DOI.
  • Valentine R; Smith GL. (Sep 2010). Inhibition of the RNA polymerase III-mediated dsDNA-sensing pathway of innate immunity by vaccinia virus protein E3. J Gen Virol. 91:2221-2229. DOI Open Access copy.
  • Lopez D; Garcia-Calvo M; Smith GL; Del Val M. (1 May 2010). Caspases in Virus-Infected Cells Contribute to Recognition by CD8(+) T Lymphocytes. JOURNAL OF IMMUNOLOGY. 184:5193-5199. Author weblink DOI.
  • McCoy LE; Fahy AS; Chen RA; Smith GL. (Sep 2010). Mutations in modified virus Ankara protein 183 render it a non-functional counterpart of B14, an inhibitor of nuclear factor kappaB activation. J Gen Virol. 91:2216-2220. DOI.
  • Osman M; Kubo T; Gill J; Neipel F; Becker M; Smith GL; Weiss R; Gazzard B; et alBoshoff C; Gotch F. Identification of human herpes virus 8-specific cytotoxic T cell responses. J. Virol. 73:6136-6140.
  • Vanderplasschen A; Smith GL. Confocal microscopy: a method to study virus binding and entry into cells. Meth. Enzymol. 307:591-607.
  • Sanderson CM; Smith GL. Cell motility and morphology: viruses in control. Exp. Revs. Molec. Med. http://www-ermm.cbcu.cam.ac.uk/99000629h.htm.
  • Plebanski M; Gilbert SC; Schneider J; Hannan CM; Layton G; Blanchard T; Becker M; Smith GL; et alSinden RE; Hill AVS. Protection from Plasmodium berghei infection by priming and boosting T cells to a single major histocompatibility class I restricted epitope with recombinant carriers suitable for human use. Eur. J. Immunol. 28:4345-4355.
  • Dixon LK; Baylis SA; Vydelingum S; Twigg SRF; Hammond JM; Hingamp PM; Bristow C; Wilkinson PJ; et alSmith GL. African swine fever virus genome variability and content. Arch. Virol. [Suppl] 7, 185-199.
  • Forrester AJ; Sullivan V; Simmons A; Blacklaws BA; Smith GL; Nash AA; Minson AC. Induction of protective immunity with antibody to herpes simplex virus type 1 glycoprotein H (gH) and analysis of the immune response to recombinant vaccinia virus. J. Gen. Virol. 72:369-375.
  • Browne H; Smith GL; Beck S; Minson AC. The MHC class 1 homologue encoded by human cytomegalovirus complexes with 2 microglobulin. Nature. 347:770-772.
  • McClean CS; Churcher MJ; Meinke J; Smith GL; Higgins G; Stanley M; Minson AC. Production and characterisation of a monoclonal antibody to human papillomavirus type 16 using recombinant vaccinia virus. J. Clin. Pathol. 43:488-492.
  • Rodriguez JF; Smith GL. Inducible gene expression from vaccinia virus vectors. Virology. 177:239-250.
  • Howard ST; Smith GL. Two early vaccinia virus genes encode polypeptides related to protein kinases. J. Gen. Virol. 70:3187-3201.
  • Kerr SM; Smith GL. Vaccinia virus encodes a polypeptide with DNA ligase activity. Nucleic Acids Res. 17:9039-9050.
  • Smith GL; Chan YS; Kerr SM. Transcriptional mapping and nucleotide sequence of a vaccinia virus gene encoding a polypeptide with extensive homology to DNA ligases. Nucleic Acids Res. 17:9051-9062.
  • Smith GL; de Carlos A; Chan YS. Vaccinia virus encodes a thymidylate kinase gene: sequence and transcriptional mapping. Nucleic Acids Res. 17:7581-7590.
  • Smith GL; Howard ST; Chan YS. Vaccinia virus encodes a family of genes with homology to serine protease inhibitors. J. Gen. Virol. 70:2333-2343.
  • Yewdell J; Bennink J; Smith GL; Moss B. Use of recombinant vaccinia viruses to examine cytotoxic T lymphocyte recognition of individual viral proteins. Adv. Exp. Med. Biol. 239:151-161.
  • Townsend ARM; Bastin J; Gould K; Brownlee GG; Andrew A; Boyle DB; Chan YS; Smith GL. Defective presentation to class I restricted CTL in vaccinia infected cells is overcome by enhanced degradation of antigen. J. Exp. Med. 168:1211-1224.
  • Browne H; Churcher M; Stanley M; Smith GL; Minson AC. Analysis of the L1 gene product of HPV 16 by expression in a vaccinia virus recombinant. J. Gen. Virol. 69:1263-1273.
  • Cranage MP; Smith GL; Bell SE; Hart H; Brown C; Bankier AT; Tomlinson PA1-; Minson AC. Identification and expression of a human cytomegalovirus (HCMV) glycoprotein with homology to EBV BXLF2 gene product, VZV gpIII and HSV-1 glycoprotein H. J. Virol. 62:1416-1422.
  • Sullivan V.; Smith GL. The herpes simplex virus type 1 US7 gene product is a 66K glycoprotein and is a target for complement-dependent virus neutralisation. J. Gen. Virol. 69:859-867.
  • Sullivan V; Smith GL. Expression and characterization of herpes simplex virus type 1 (HSV-1) glycoprotein G (gG) by recombinant vaccinia virus: neutralisation of HSV-1 infectivity with anti-gG antibody. J. Gen. Virol. 68:2587-2598.
  • Smith GL; Levin J; Palese P; Moss B. Synthesis and cellular location of the ten influenza virus polypeptides individually expressed by recombinant vaccinia viruses. Virology. 160:336-345.
  • Tomley F; Boursnell M; Binns M; Mockett A; Brown TDK; Smith GL. Expression of the IBV spike protein by recombinant vaccinia virus and induction of neutralising antibodies in vaccinated mice. J. Gen. Virol. 68:2291-2298.
  • Smith GL; Hay AJ. (1982). Replication of the influenza virus genome. Virology. 118:96-108.
  • Mackett M; Smith GL; Moss B. (1982). Vaccinia virus: a selectable eukaryotic cloning and expression vector. Proc. Natl. Acad. Sci. USA. 79:7415-7419.
  • Smith GL; Mackett M; Moss B. (1984). Recombinant vaccinia viruses as new live vaccines. Biotechnology Genetic Engineering Reviews. 2:387-405.
  • Smith GL; Moss B. (1984). Use of vaccinia virus as a vector for the construction of live recombinant vaccines. BioEssays. 1:120-124.
  • Bennink JR; Yewdell JW; Smith GL; Moss B. (1 Apr 1987). Anti-influenza cytotoxic T lymphocytes recognise the three viral polymerases and a nonstructural protein: responsiveness to individual virus antigens is major histocompatibility controlled. J. Virol. 61:1098-1102.
  • Smith GL; Mackett M; Moss B. (1983). Infectious vaccinia virus recombinants express hepatitis B virus surface antigen. Nature. 302:490-495.
  • Smith GL; Moss B. (1983). Infectious poxvirus vectors have capacity for at least 25,000 base pairs of foreign DNA. Gene. 25:21-28.
  • Smith GL; Murphy BR; Moss B. (1983). Construction and characterization of an infectious vaccinia virus recombinant that expresses the influenza virus hemagglutinin and induces resistance to influenza virus infection in hamsters. Proc. Natl. Acad. Sci. USA. 80:7155-7159.
  • Mackett M; Smith GL; Moss B. (1984). General method for the production and selection of vaccinia virus recombinants expressing foreign genes. J. Virol. 49:857-864.
  • Smith GL; Godson NG; Nussenzweig V; Nussenzweig RS; Barnwell J; Moss B. (1984). Plasmodium knowlesi sporozoite antigen: expression by infectious recombinant vaccinia virus. Science. 224:337-339.
  • Moss B; Smith GL; Gerin JL; Purcell RH. (1984). Live recombinant vaccinia virus protects chimpanzees against hepatitis B. Nature. 311:67-69.
  • Bennink JR; Yewdell JW; Smith GL; Moller C; Moss B. (1984). Recombinant vaccinia virus primes and stimulates influenza haemagglutinin-specific cytotoxic T cells. Nature. 311:578-579.
  • Smith GL; Moss B. (1984). Vaccinia virus expression vectors: construction, properties and applications. BioTechniques. 2:306-312.
  • Yewdell JW; Bennink JR; Smith GL; Moss B. (1985). Influenza A virus nucleoprotein is a major antigen for influenza A virus cross-reactive cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA. 82:1785-1789.
  • Buller RML; Smith GL; Cremer K; Notkins AL; Moss B. (1985). Decreased virulence of recombinant vaccinia virus expression vectors is associated with a TK negative phenotype. Nature. 317:812-815.
  • Bennink JR; Yewdell JW; Smith GL; Moss B. (1986). Recognition of cloned influenza virus haemagglutinin gene products by cytotoxic T lymphocytes. J. Virol. 57:786-791.
  • Langford CJ; Edwards SJ; Smith GL; Mitchell GF; Moss B; Kemp DJ; Anders RF. (1986). Anchoring a secreted plasmodial antigen on the surface of recombinant vaccinia virus infected cells increases its immunogenicity. Molecular Cellular Biology. 6:3191-3199.
  • Smith GL; Cheng K; Moss B. (1986). Vaccinia virus: an expression vector for genes from parasites. Parasitology. 92S:109-118.
  • Cheng K; Smith GL; Moss B. (1986). Hepatitis B virus large surface protein is not secreted but is immunogenic when selectively expressed by recombinant vaccinia virus. J. Virol. 60:337-344.
  • Mackett M; Smith GL. (1986). Vaccinia virus expression vectors. J. Gen. Virol. 67:2067-2082.
  • Cranage MP; Kouzarides T; Bankier AT; Satchwell S; Weston K; Tomlinson P; Barrell BG; Bell SE; et alMinson AC; Smith GL. (1986). Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralising antibodies via its expression in recombinant vaccinia virus. EMBO Journal. 5:3057-3063.
  • MCMICHAEL AJ; MICHIE CA; GOTCH FM; SMITH GL; MOSS B. (1 Apr 1986). RECOGNITION OF INFLUENZA-A VIRUS NUCLEOPROTEIN BY HUMAN CYTOTOXIC LYMPHOCYTES-T. JOURNAL OF GENERAL VIROLOGY. 67:719-726. Author weblink DOI.
  • Gotch FM; McMichael AJ; Smith GL; Moss B. (1987). Identification of the viral molecules recognized by influenza specific human cytotoxic T lymphocytes. J. Exp. Med. 165:408-416.
  • Good MF; Maloy WL; Lunde MN; Margalit H; Cornette JL; Smith GL; Moss B; Miller LH; et alBerzofsky JA. (1987). Construction of a synthetic immunogen: use of new T-helper epitope on the malaria circumsporozoite protein. Science. 235:1059-1062.
  • Borysiewicz LK; Hickling JK; Graham S; Sinclair J; Cranage MP; Smith GL; Sissons JG. (1 Sep 1988). Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses. J Exp Med. 168:919-931.
  • ZHOU J; CRAWFORD L; MCLEAN L; SUN XY; STANLEY M; ALMOND N; SMITH GL. (1 Sep 1990). INCREASED ANTIBODY-RESPONSES TO HUMAN PAPILLOMAVIRUS TYPE-16 L1 PROTEIN EXPRESSED BY RECOMBINANT VACCINIA VIRUS LACKING SERINE PROTEASE INHIBITOR GENES. JOURNAL OF GENERAL VIROLOGY. 71:2185-2190. Author weblink DOI.
  • Rodriguez JF; Smith GL. (25 Sep 1990). IPTG-dependent vaccinia virus: identification of a virus protein enabling virion envelopment by Golgi membrane and egress. Nucleic Acids Res. 18:5347-5351.
  • HOWARD ST; CHAN YS; SMITH GL. (1 Feb 1991). VACCINIA VIRUS HOMOLOGS OF THE SHOPE FIBROMA VIRUS INVERTED TERMINAL REPEAT PROTEINS AND A DISCONTINUOUS ORF RELATED TO THE TUMOR-NECROSIS-FACTOR RECEPTOR FAMILY. VIROLOGY. 180:633-647. Author weblink DOI.
  • Kerr SM; Smith GL. (Feb 1991). Vaccinia virus DNA ligase is nonessential for virus replication: recovery of plasmids from virus-infected cells. Virology. 180:625-632.
  • SMITH GL; CHAN YS. (1 Mar 1991). 2 VACCINIA VIRUS PROTEINS STRUCTURALLY RELATED TO THE INTERLEUKIN-1 RECEPTOR AND THE IMMUNOGLOBULIN SUPERFAMILY. JOURNAL OF GENERAL VIROLOGY. 72:511-518. Author weblink DOI.
  • Smith GL; Chan YS; Howard ST. (Jun 1991). Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the right inverted terminal repeat. J Gen Virol. 72 ( Pt 6):1349-1376.
  • SMITH GL; CHAN YS; HOWARD ST. (1 Jun 1991). NUCLEOTIDE-SEQUENCE OF 42 KBP OF VACCINIA VIRUS-STRAIN WR FROM NEAR THE RIGHT INVERTED TERMINAL REPEAT. JOURNAL OF GENERAL VIROLOGY. 72:1349-1376. Author weblink DOI.
  • Smith GL. (Oct 1991). Vaccinia virus vectors for gene expression. Curr Opin Biotechnol. 2:713-717.
  • Hughes SJ; Johnston LH; de Carlos A; Smith GL. (25 Oct 1991). Vaccinia virus encodes an active thymidylate kinase that complements a cdc8 mutant of Saccharomyces cerevisiae. J Biol Chem. 266:20103-20109.
  • Kerr SM; Johnston LH; Odell M; Duncan SA; Law KM; Smith GL. (Dec 1991). Vaccinia DNA ligase complements Saccharomyces cerevisiae cdc9, localizes in cytoplasmic factories and affects virulence and virus sensitivity to DNA damaging agents. EMBO J. 10:4343-4350.
  • Duncan SA; Smith GL. (Mar 1992). Identification and characterization of an extracellular envelope glycoprotein affecting vaccinia virus egress. J Virol. 66:1610-1621.
  • LAW KM; SMITH GL. (1 Mar 1992). A VACCINIA SERINE PROTEASE INHIBITOR WHICH PREVENTS VIRUS-INDUCED CELL-FUSION. JOURNAL OF GENERAL VIROLOGY. 73:549-557. Author weblink DOI.
  • DUNCAN SA; SMITH GL. (1 May 1992). VACCINIA VIRUS GENE SALF5R IS NONESSENTIAL FOR VIRUS-REPLICATION INVITRO AND INVIVO. JOURNAL OF GENERAL VIROLOGY. 73:1235-1242. Author weblink DOI.
  • Moore JB; Smith GL. (May 1992). Steroid hormone synthesis by a vaccinia enzyme: a new type of virus virulence factor. EMBO J. 11:1973-1980.
  • Engelstad M; Howard ST; Smith GL. (Jun 1992). A constitutively expressed vaccinia gene encodes a 42-kDa glycoprotein related to complement control factors that forms part of the extracellular virus envelope. Virology. 188:801-810.
  • HAMMOND JM; KERR SM; SMITH GL; DIXON LK. (11 Jun 1992). AN AFRICAN SWINE FEVER VIRUS GENE WITH HOMOLOGY TO DNA LIGASES. NUCLEIC ACIDS RESEARCH. 20:2667-2671. Author weblink DOI.
  • Alcamí A; Smith GL. (2 Oct 1992). A soluble receptor for interleukin-1 beta encoded by vaccinia virus: a novel mechanism of virus modulation of the host response to infection. Cell. 71:153-167.
  • AGUADO B; SELMES IP; SMITH GL. (1 Nov 1992). NUCLEOTIDE-SEQUENCE OF 21.8 KBP OF VARIOLA MAJOR VIRUS-STRAIN HARVEY AND COMPARISON WITH VACCINIA VIRUS. JOURNAL OF GENERAL VIROLOGY. 73:2887-2902. Author weblink DOI.
  • Aguado B; Selmes IP; Smith GL. (Nov 1992). Nucleotide sequence of 21.8 kbp of variola major virus strain Harvey and comparison with vaccinia virus. J Gen Virol. 73 ( Pt 11):2887-2902.
  • Banham AH; Smith GL. (Dec 1992). Vaccinia virus gene B1R encodes a 34-kDa serine/threonine protein kinase that localizes in cytoplasmic factories and is packaged into virions. Virology. 191:803-812.
  • Baylis SA; Dixon LK; Vydelingum S; Smith GL. (5 Dec 1992). African swine fever virus encodes a gene with extensive homology to type II DNA topoisomerases. J Mol Biol. 228:1003-1010.
  • ALCAMI A; SMITH GL. (26 Jan 1993). VACCINIA VIRUS ENCODES A SECRETED RECEPTOR FOR INTERLEUKIN-1 THAT MODULATES THE HOST RESPONSE TO INFECTION. JOURNAL OF CELLULAR BIOCHEMISTRY. 72-72. Author weblink.
  • ENGELSTAD M; SMITH GL. (13 Mar 1993). CHARACTERIZATION OF A VACCINIA VIRUS 42 KD ENVELOPE GLYCOPROTEIN WITH HOMOLOGY TO COMPLEMENT CONTROL PROTEINS. JOURNAL OF CELLULAR BIOCHEMISTRY. 55-55. Author weblink.
  • BLAKE NW; KETTLE S; GOULD K; BASTIN J; TOWNSEND A; SMITH GL. (13 Mar 1993). DO VACCINIA VIRUS-ENCODED SERPINS INHIBIT ANTIGEN PRESENTATION TO CLASS I-RESTRICTED CTL. JOURNAL OF CELLULAR BIOCHEMISTRY. 54-54. Author weblink.
  • Banham AH; Leader DP; Smith GL. (19 Apr 1993). Phosphorylation of ribosomal proteins by the vaccinia virus B1R protein kinase. FEBS Lett. 321:27-31.
  • Engelstad M; Smith GL. (Jun 1993). The vaccinia virus 42-kDa envelope protein is required for the envelopment and egress of extracellular virus and for virus virulence. Virology. 194:627-637. DOI.
  • Baylis SA; Banham AH; Vydelingum S; Dixon LK; Smith GL. (Aug 1993). African swine fever virus encodes a serine protein kinase which is packaged into virions. J Virol. 67:4549-4556.
  • Smith GL. (Sep 1993). Vaccinia virus glycoproteins and immune evasion. The sixteenth Fleming Lecture. J Gen Virol. 74 ( Pt 9):1725-1740.
  • BAYLIS SA; TWIGG SRF; VYDELINGUM S; DIXON LK; SMITH GL. (1 Sep 1993). 3 AFRICAN SWINE FEVER VIRUS GENES ENCODING PROTEINS WITH HOMOLOGY TO PUTATIVE HELICASES OF VACCINIA VIRUS. JOURNAL OF GENERAL VIROLOGY. 74:1969-1974. Author weblink DOI.
  • Baylis SA; Twigg SR; Vydelingum S; Dixon LK; Smith GL. (Sep 1993). Three African swine fever virus genes encoding proteins with homology to putative helicases of vaccinia virus. J Gen Virol. 74 ( Pt 9):1969-1974.
  • SMITH GL. (1 Sep 1993). VACCINIA VIRUS GLYCOPROTEINS AND IMMUNE EVASION - THE 16TH FLEMING LECTURE. JOURNAL OF GENERAL VIROLOGY. 74:1725-1740. Author weblink DOI.
  • VYDELINGUM S; BAYLIS SA; BRISTOW C; SMITH GL; DIXON LK. (1 Oct 1993). DUPLICATED GENES WITHIN THE VARIABLE RIGHT END OF THE GENOME OF A PATHOGENIC ISOLATE OF AFRICAN SWINE FEVER VIRUS. JOURNAL OF GENERAL VIROLOGY. 74:2125-2130. Author weblink DOI.
  • Alcamí A; Smith GL. (29 Nov 1993). Comment on the paper by Shchelkunov et al. (1993) FEBS Letters 319, 80-83. Two genes encoding poxvirus cytokine receptors are disrupted or deleted in variola virus. FEBS Lett. 335:136-137.
  • BANHAM AH; SMITH GL. (1 Dec 1993). CHARACTERIZATION OF VACCINIA VIRUS GENE-B12R. JOURNAL OF GENERAL VIROLOGY. 74:2807-2812. Author weblink DOI.
  • Banham AH; Smith GL. (Dec 1993). Characterization of vaccinia virus gene B12R. J Gen Virol. 74 ( Pt 12):2807-2812.
  • Smith GL. (Mar 1994). Virus strategies for evasion of the host response to infection. Trends Microbiol. 2:81-88.
  • Wilcock D; Smith GL. (Jul 1994). Vaccinia virus core protein VP8 is required for virus infectivity, but not for core protein processing or for INV and EEV formation. Virology. 202:294-304. DOI.
  • DIXON LK; TWIGG SRF; BAYLIS SA; VYDELINGUM S; BRISTOW C; HAMMOND JM; SMITH GL. (1 Jul 1994). NUCLEOTIDE-SEQUENCE OF A 55 KBP REGION FROM THE RIGHT END OF THE GENOME OF A PATHOGENIC AFRICAN SWINE FEVER VIRUS ISOLATE (MALAWI LIL20/1). JOURNAL OF GENERAL VIROLOGY. 75:1655-1684. Author weblink DOI.
  • SKINNER MA; MOORE JB; BINNS MM; SMITH GL; BOURSNELL MEG. (1 Sep 1994). DELETION OF FOWLPOX VIRUS HOMOLOGS OF VACCINIA VIRUS GENES BETWEEN THE 3-BETA-HYDROXYSTEROID DEHYDROGENASE (A44L) AND DNA-LIGASE (A50R) GENES. JOURNAL OF GENERAL VIROLOGY. 75:2495-2498. Author weblink DOI.
  • Parkinson JE; Smith GL. (Oct 1994). Vaccinia virus gene A36R encodes a M(r) 43-50 K protein on the surface of extracellular enveloped virus. Virology. 204:376-390. DOI.
  • ALCAMI A; HIGBEE NC; SMITH GL. (5 Jan 1995). CONTROL OF FEVER BY THE VACCINIA VIRUS IL-1-BETA RECEPTOR. JOURNAL OF CELLULAR BIOCHEMISTRY. 288-288. Author weblink.
  • SYMONS JA; ALCAMI A; SMITH GL. (5 Jan 1995). VACCINIA VIRUS ENCODES A NOVEL SOLUBLE TYPE-I INTERFERON (IFN) RECEPTOR UNRELATED TO EXISTING IFN CELL-SURFACE RECEPTORS. JOURNAL OF CELLULAR BIOCHEMISTRY. 293-293. Author weblink.
  • SMITH GL; ALCAMI A. (5 Jan 1995). VACCINIA AND COWPOX VIRUSES ENCODE SOLUBLE IFN-GAMMA RECEPTORS WITH NOVEL BROAD SPECIES-SPECIFICITY. JOURNAL OF CELLULAR BIOCHEMISTRY. 293-293. Author weblink.
  • Kettle S; Blake NW; Law KM; Smith GL. (10 Jan 1995). Vaccinia virus serpins B13R (SPI-2) and B22R (SPI-1) encode M(r) 38.5 and 40K, intracellular polypeptides that do not affect virus virulence in a murine intranasal model. Virology. 206:136-147.
  • SUN HC; JACOBS SC; SMITH GL; DIXON LK; PARKHOUSE RME. (1 May 1995). AFRICAN SWINE FEVER VIRUS GENE J13L ENCODES A 25-27 KDA VIRION PROTEIN WITH VARIABLE NUMBERS OF AMINO-ACID REPEATS. JOURNAL OF GENERAL VIROLOGY. 76:1117-1127. Author weblink DOI.
  • Symons JA; Alcamí A; Smith GL. (19 May 1995). Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity. Cell. 81:551-560.
  • Alcamí A; Smith GL. (Aug 1995). Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificity. J Virol. 69:4633-4639.
  • BLAKE NW; KETTLE S; LAW KM; GOULD K; BASTIN J; TOWNSEND ARM; SMITH GL. (1 Sep 1995). VACCINIA VIRUS SERPINS B13R AND B22R DO NOT INHIBIT ANTIGEN PRESENTATION TO CLASS I-RESTRICTED CYTOTOXIC T-LYMPHOCYTES. JOURNAL OF GENERAL VIROLOGY. 76:2393-2398. Author weblink DOI.
  • Blake NW; Kettle S; Law KM; Gould K; Bastin J; Townsend AR; Smith GL. (Sep 1995). Vaccinia virus serpins B13R and B22R do not inhibit antigen presentation to class I-restricted cytotoxic T lymphocytes. J Gen Virol. 76 ( Pt 9):2393-2398.
  • Alcamí A; Smith GL. (Oct 1995). Cytokine receptors encoded by poxviruses: a lesson in cytokine biology. Immunol Today. 16:474-478.
  • Parkinson JE; Sanderson CM; Smith GL. (1 Dec 1995). The vaccinia virus A38L gene product is a 33-kDa integral membrane glycoprotein. Virology. 214:177-188. DOI.
  • McIntosh AA; Smith GL. (Jan 1996). Vaccinia virus glycoprotein A34R is required for infectivity of extracellular enveloped virus. J Virol. 70:272-281.
  • Wilcock D; Smith GL. (Feb 1996). Vaccinia virions lacking core protein VP8 are deficient in early transcription. J Virol. 70:934-943.
  • Bayliss CD; Smith GL. (Feb 1996). Vaccinia virion protein I8R has both DNA and RNA helicase activities: implications for vaccinia virus transcription. J Virol. 70:794-800.
  • Sanderson CM; Parkinson JE; Hollinshead M; Smith GL. (Feb 1996). Overexpression of the vaccinia virus A38L integral membrane protein promotes Ca2+ influx into infected cells. J Virol. 70:905-914.
  • Cryz S; Davis SS; Gregoriadis G; Grimaud JA; Kourilsky P; Selkirk ME; Slaoui M; Smith GL. (1 May 1996). European commission COST/STD initiative - Vaccine delivery systems. VACCINE. 14:665-690. Author weblink.
  • Odell M; Kerr SM; Smith GL. (1 Jul 1996). Ligation of double-stranded and single-stranded [oligo(dT)] DNA by vaccinia virus DNA ligase. Virology. 221:120-129. DOI.
  • Alcamí A; Smith GL. (Aug 1996). Receptors for gamma-interferon encoded by poxviruses: implications for the unknown origin of vaccinia virus. Trends Microbiol. 4:321-326.
  • Smith GL. (Aug 1996). Virus proteins that bind cytokines, chemokines or interferons. Curr Opin Immunol. 8:467-471.
  • Alcamí A; Smith GL. (Sep 1996). Soluble interferon-gamma receptors encoded by poxviruses. Comp Immunol Microbiol Infect Dis. 19:305-317.
  • Alcamí A; Smith GL. (1 Oct 1996). A mechanism for the inhibition of fever by a virus. Proc Natl Acad Sci U S A. 93:11029-11034.
  • Blanchard TJ; Andrea P; Alcami A; Smith GL. (1 Nov 1996). Modified Virus Ankara cytokine receptor profile. IMMUNOLOGY. 89:EE357-EE357. Author weblink.
  • Smith GL. (1 Nov 1996). Interfering with interferon by vaccinia virus. IMMUNOLOGY. 89:SE107-SE107. Author weblink.
  • Bayliss CD; Wilcock D; Smith GL. (1 Nov 1996). Stimulation of vaccinia virion DNA helicase 18R, but not A18R, by a vaccinia core protein L4R, an ssDNA binding protein. JOURNAL OF GENERAL VIROLOGY. 77:2827-2831. Author weblink DOI.
  • Symons JA; Smith GL. (1 Nov 1996). Role of the vaccinia virus soluble interferon gamma receptor in virus pathogenesis. IMMUNOLOGY. 89:EE361-EE361. Author weblink.
  • Blanchard T; RowlandJones S; Gotch F; McMichael A; Smith GL. (21 Dec 1996). Future vaccines for HIV. LANCET. 348:1741-1741. Author weblink DOI.
  • Kettle S; Alcami A; Khanna A; Ehret R; Jassoy C; Smith GL. (1 Mar 1997). Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1 beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1 beta-induced fever. JOURNAL OF GENERAL VIROLOGY. 78:677-685. Author weblink.
  • Vanderplasschen A; Smith GL. (May 1997). A novel virus binding assay using confocal microscopy: demonstration that the intracellular and extracellular vaccinia virions bind to different cellular receptors. J Virol. 71:4032-4041.
  • Liptakova H; Kontsekova E; Alcami A; Smith GL; Kontsek P. (26 May 1997). Analysis of an interaction between the soluble vaccinia virus-coded type I interferon (IFN)-receptor and human IFN-alpha 1 and IFN-alpha 2. VIROLOGY. 232:86-90. Author weblink DOI.
  • Vanderplasschen A; Hollinshead M; Smith GL. (1 Aug 1997). Antibodies against vaccinia virus do not neutralize extracellular enveloped virus but prevent virus release from infected cells and comet formation. JOURNAL OF GENERAL VIROLOGY. 78:2041-2048. Author weblink.
  • Smith GL; Symons JA; Khanna A; Vanderplasschen A; Alcamí A. (Oct 1997). Vaccinia virus immune evasion. Immunol Rev. 159:137-154.
  • Bayliss CD; Smith GL. (15 Oct 1997). Vaccinia virion protein VP8, the 25 kDa product of the L4R gene, binds single-stranded DNA and RNA with similar affinity. Nucleic Acids Res. 25:3984-3990.
  • Vanderplasschen A; Smith GL. (1 Nov 1997). Two centuries of vaccination. ANNALES DE MEDECINE VETERINAIRE. 141:425-+.
  • Hanke T; Blanchard TJ; Schneider J; Ogg GS; Tan R; Becker M; Gilbert SC; Hill AV; et alSmith GL; McMichael A. (Jan 1998). Immunogenicities of intravenous and intramuscular administrations of modified vaccinia virus Ankara-based multi-CTL epitope vaccine for human immunodeficiency virus type 1 in mice. J Gen Virol. 79 ( Pt 1):83-90.
  • Smith GL; Vanderplasschen A. (1998). Extracellular enveloped vaccinia virus. Entry, egress, and evasion. Adv Exp Med Biol. 440:395-414.
  • Alcamí A; Symons JA; Collins PD; Williams TJ; Smith GL. (15 Jan 1998). Blockade of chemokine activity by a soluble chemokine binding protein from vaccinia virus. J Immunol. 160:624-633.
  • Sanderson CM; Way M; Smith GL. (Feb 1998). Virus-induced cell motility. J Virol. 72:1235-1243.
  • Major JR; Smith GL; MacPherson GG. (1 Jan 1998). Dendritic cells generated in vitro or derived ex vivo are poorly infectable by vaccinia virus. JOURNAL OF LEUKOCYTE BIOLOGY. 59-59. Author weblink.
  • Sanz-Ezquerro JJ; Santaren JF; Sierra T; Aragon T; Ortega J; Ortin J; Smith GL; Nieto A. (1 Mar 1998). The PA influenza virus polymerase subunit is a phosphorylated protein. JOURNAL OF GENERAL VIROLOGY. 79:471-478. Author weblink.
  • Mathew E; Sanderson CM; Hollinshead M; Smith GL. (Mar 1998). The extracellular domain of vaccinia virus protein B5R affects plaque phenotype, extracellular enveloped virus release, and intracellular actin tail formation. J Virol. 72:2429-2438.
  • Hanke T; Blanchard TJ; Schneider J; Hannan CM; Becker M; Gilbert SC; Hill AV; Smith GL; et alMcMichael A. (Mar 1998). Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime. Vaccine. 16:439-445.
  • Smith GL. (1 Apr 1998). Immunomodulation by virus infection - Introduction. SEMINARS IN VIROLOGY. 8:359-359. DOI.
  • Vanderplasschen A; Hollinshead M; Smith GL. (Apr 1998). Intracellular and extracellular vaccinia virions enter cells by different mechanisms. J Gen Virol. 79 ( Pt 4):877-887.
  • Alcami A; Symons JA; Khanna A; Smith GL. (1 Apr 1998). Poxviruses: Capturing cytokines and chemokines. SEMINARS IN VIROLOGY. 8:419-427. Author weblink DOI.
  • Smith GL; Symons JA; Alcami A. (1 Apr 1998). Poxviruses: Interfering with interferon. SEMINARS IN VIROLOGY. 8:409-418. Author weblink DOI.
  • Schneider J; Gilbert SC; Blanchard TJ; Hanke T; Robson KJ; Hannan CM; Becker M; Sinden R; et alSmith GL; Hill AV. (Apr 1998). Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nat Med. 4:397-402.
  • Jacobs SC; Dixon LK; Brookes SM; Smith GL. (1 May 1998). Expression of African swine fever virus envelope protein j13L inhibits vaccinia virus morphogenesis. JOURNAL OF GENERAL VIROLOGY. 79:1169-1178. Author weblink.
  • Blanchard TJ; Alcami A; Andrea P; Smith GL. (May 1998). Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine. J Gen Virol. 79 ( Pt 5):1159-1167.
  • Sanderson CM; Frischknecht F; Way M; Hollinshead M; Smith GL. (Jun 1998). Roles of vaccinia virus EEV-specific proteins in intracellular actin tail formation and low pH-induced cell-cell fusion. J Gen Virol. 79 ( Pt 6):1415-1425.
  • Vanderplasschen A; Mathew E; Hollinshead M; Sim RB; Smith GL. (23 Jun 1998). Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope. Proc Natl Acad Sci U S A. 95:7544-7549.
  • Puehler F; Weining KC; Symons JA; Smith GL; Staeheli P. (1 Sep 1998). Vaccinia virus-encoded cytokine receptor binds and neutralizes chicken interferon-gamma. VIROLOGY. 248:231-240. Author weblink DOI.
  • Sanderson CM; Smith GL. (Dec 1998). Vaccinia virus induces Ca2+-independent cell-matrix adhesion during the motile phase of infection. J Virol. 72:9924-9933.
  • Smith GL. (Jan 1999). Vaccinia virus immune evasion. Immunol Lett. 65:55-62.
  • Smith GL; Symons JA; Alcamí A. (1999). Immune modulation by proteins secreted from cells infected by vaccinia virus. Arch Virol Suppl. 15:111-129.
  • Hollinshead M; Vanderplasschen A; Smith GL; Vaux DJ. (Feb 1999). Vaccinia virus intracellular mature virions contain only one lipid membrane. J Virol. 73:1503-1517.
  • Hanke T; Neumann VC; Blanchard TJ; Sweeney P; Hill AV; Smith GL; McMichael A. (12 Feb 1999). Effective induction of HIV-specific CTL by multi-epitope using gene gun in a combined vaccination regime. Vaccine. 17:589-596.
  • Goatley LC; Marron MB; Jacobs SC; Hammond JM; Miskin JE; Abrams CC; Smith GL; Dixon LK. (1 Mar 1999). Nuclear and nucleolar localization of an African swine fever virus protein, I14L, that is similar to the herpes simplex virus-encoded virulence factor ICP34.5. JOURNAL OF GENERAL VIROLOGY. 80:525-535. Author weblink.
  • Gilbert SC; Schneider J; Plebanski M; Hannan CM; Blanchard TJ; Smith GL; Hill AV. (Mar 1999). Ty virus-like particles, DNA vaccines and Modified Vaccinia Virus Ankara; comparisons and combinations. Biol Chem. 380:299-303. DOI.
  • Rottger S; Frischknecht F; Reckmann I; Smith GL; Way M. (1 Apr 1999). Interactions between vaccinia virus IEV membrane proteins and their roles in IEV assembly and actin tail formation. JOURNAL OF VIROLOGY. 73:2863-2875. Author weblink.
  • Alcami A; Khanna A; Paul NL; Smith GL. (1 Apr 1999). Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumour necrosis factor receptors. JOURNAL OF GENERAL VIROLOGY. 80:949-959. Author weblink.
  • Blanchard T; Smith GL; Whittle H. (31 Jul 1999). Vaccines for smallpox. LANCET. 354:422-422. Author weblink DOI.
  • Wilcock D; Duncan SA; Traktman P; Zhang WH; Smith GL. (1 Aug 1999). The vaccinia virus A4OR gene product is a nonstructural, type II membrane glycoprotein that is expressed at the cell surface. JOURNAL OF GENERAL VIROLOGY. 80:2137-2148. Author weblink.
  • Hanke T; Samuel RV; Blanchard TJ; Neumann VC; Allen TM; Boyson JE; Sharpe SA; Cook N; et alSmith GL; Watkins DI; Cranage MP; McMichael AJ. (Sep 1999). Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen. J Virol. 73:7524-7532.
  • Tscharke DC; Smith GL. (1 Oct 1999). A model for vaccinia virus pathogenesis and immunity based on intradermal injection of mouse ear pinnae. JOURNAL OF GENERAL VIROLOGY. 80:2751-2755. Author weblink.
  • Mathew EC; Sanderson CM; Hollinshead R; Hollinshead M; Grimley R; Smith GL. (5 Dec 1999). The effects of targeting the vaccinia virus B5R protein to the endoplasmic reticulum on virus morphogenesis and dissemination. Virology. 265:131-146. DOI.
  • Sanderson CM; Hollinshead M; Smith GL. (Jan 2000). The vaccinia virus A27L protein is needed for the microtubule-dependent transport of intracellular mature virus particles. J Gen Virol. 81:47-58.
  • Price N; Tscharke DC; Hollinshead M; Smith GL. (1 Feb 2000). Vaccinia virus gene B7R encodes an 18-kDa protein that is resident in the endoplasmic reticulum and affects virus virulence. Virology. 267:65-79. DOI.
  • van Eijl H; Hollinshead M; Smith GL. (25 May 2000). The vaccinia virus A36R protein is a type Ib membrane protein present on intracellular but not extracellular enveloped virus particles. Virology. 271:26-36. DOI.
  • Bowie A; Kiss-Toth E; Symons JA; Smith GL; Dower SK; O'Neill LA. (29 Aug 2000). A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling. Proc Natl Acad Sci U S A. 97:10162-10167. DOI.
  • Dorrell L; O'Callaghan CA; Britton W; Hambleton S; McMichael A; Smith GL; Rowland-Jones S; Blanchard TJ. (15 Sep 2000). Recombinant modified vaccinia virus Ankara efficiently restimulates human cytotoxic T lymphocytes in vitro. Vaccine. 19:327-336.
  • Zhang WH; Wilcock D; Smith GL. (Dec 2000). Vaccinia virus F12L protein is required for actin tail formation, normal plaque size, and virulence. J Virol. 74:11654-11662.
  • Alcamí A; Symons JA; Smith GL. (Dec 2000). The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral effects of IFN. J Virol. 74:11230-11239.
  • Law M; Smith GL. (1 Feb 2001). Antibody neutralization of the extracellular enveloped form of vaccinia virus. Virology. 280:132-142. DOI.
  • Lee HJ; Essani K; Smith GL. (15 Mar 2001). The genome sequence of Yaba-like disease virus, a yatapoxvirus. Virology. 281:170-192. DOI.
  • Mathew EC; Sanderson CM; Hollinshead R; Smith GL. (May 2001). A mutational analysis of the vaccinia virus B5R protein. J Gen Virol. 82:1199-1213.
  • Potter P; Tourdot S; Blanchard T; Smith GL; Gould KG. (May 2001). Differential processing and presentation of the H-2D(b)-restricted epitope from two different strains of influenza virus nucleoprotein. J Gen Virol. 82:1069-1074.
  • Hollinshead M; Rodger G; Van Eijl H; Law M; Hollinshead R; Vaux DJ; Smith GL. (23 Jul 2001). Vaccinia virus utilizes microtubules for movement to the cell surface. J Cell Biol. 154:389-402.
  • Almazán F; Tscharke DC; Smith GL. (Aug 2001). The vaccinia virus superoxide dismutase-like protein (A45R) is a virion component that is nonessential for virus replication. J Virol. 75:7018-7029. DOI.
  • Gardner JD; Tscharke DC; Reading PC; Smith GL. (Sep 2001). Vaccinia virus semaphorin A39R is a 50-55 kDa secreted glycoprotein that affects the outcome of infection in a murine intradermal model. J Gen Virol. 82:2083-2093.
  • Ng A; Tscharke DC; Reading PC; Smith GL. (Sep 2001). The vaccinia virus A41L protein is a soluble 30 kDa glycoprotein that affects virus virulence. J Gen Virol. 82:2095-2105.
  • Schneider J; Langermans JA; Gilbert SC; Blanchard TJ; Twigg S; Naitza S; Hannan CM; Aidoo M; et alCrisanti A; Robson KJ; Smith GL; Hill AV; Thomas AW. (14 Sep 2001). A prime-boost immunisation regimen using DNA followed by recombinant modified vaccinia virus Ankara induces strong cellular immune responses against the Plasmodium falciparum TRAP antigen in chimpanzees. Vaccine. 19:4595-4602.
  • Feng CG; Blanchard TJ; Smith GL; Hill AV; Britton WJ. (Dec 2001). Induction of CD8+ T-lymphocyte responses to a secreted antigen of Mycobacterium tuberculosis by an attenuated vaccinia virus. Immunol Cell Biol. 79:569-575. DOI.
  • van Eijl H; Hollinshead M; Rodger G; Zhang WH; Smith GL. (Jan 2002). The vaccinia virus F12L protein is associated with intracellular enveloped virus particles and is required for their egress to the cell surface. J Gen Virol. 83:195-207.
  • Law M; Hollinshead R; Smith GL. (Jan 2002). Antibody-sensitive and antibody-resistant cell-to-cell spread by vaccinia virus: role of the A33R protein in antibody-resistant spread. J Gen Virol. 83:209-222.
  • Reading PC; Khanna A; Smith GL. (20 Jan 2002). Vaccinia virus CrmE encodes a soluble and cell surface tumor necrosis factor receptor that contributes to virus virulence. Virology. 292:285-298. DOI.
  • Rodger G; Smith GL. (Feb 2002). Replacing the SCR domains of vaccinia virus protein B5R with EGFP causes a reduction in plaque size and actin tail formation but enveloped virions are still transported to the cell surface. J Gen Virol. 83:323-332.
  • Alcamí A; Smith GL. (Mar 2002). The vaccinia virus soluble interferon-gamma receptor is a homodimer. J Gen Virol. 83:545-549.
  • Smith GL. (1 Mar 2002). Chemokine inhibitors from viruses. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Price N; Tscharke DC; Smith GL. (Apr 2002). The vaccinia virus B9R protein is a 6 kDa intracellular protein that is non-essential for virus replication and virulence. J Gen Virol. 83:873-878.
  • Gubser C; Smith GL. (Apr 2002). The sequence of camelpox virus shows it is most closely related to variola virus, the cause of smallpox. J Gen Virol. 83:855-872.
  • Tscharke DC; Smith GL. (Jul 2002). Notes on transient host range selection for engineering vaccinia virus strain MVA. Biotechniques. 33:186-188.
  • Smith GL; McFadden G. (Jul 2002). Smallpox: anything to declare?. Nat Rev Immunol. 2:521-527. DOI.
  • Bartlett N; Symons JA; Tscharke DC; Smith GL. (Aug 2002). The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence. J Gen Virol. 83:1965-1976.
  • Tscharke DC; Reading PC; Smith GL. (Aug 2002). Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes. J Gen Virol. 83:1977-1986.
  • Symons JA; Tscharke DC; Price N; Smith GL. (Aug 2002). A study of the vaccinia virus interferon-gamma receptor and its contribution to virus virulence. J Gen Virol. 83:1953-1964.
  • Goatley LC; Twigg SR; Miskin JE; Monaghan P; St-Arnaud R; Smith GL; Dixon LK. (Oct 2002). The African swine fever virus protein j4R binds to the alpha chain of nascent polypeptide-associated complex. J Virol. 76:9991-9999.
  • Krauss O; Hollinshead R; Hollinshead M; Smith GL. (Oct 2002). An investigation of incorporation of cellular antigens into vaccinia virus particles. J Gen Virol. 83:2347-2359.
  • Symons JA; Adams E; Tscharke DC; Reading PC; Waldmann H; Smith GL. (Nov 2002). The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model. J Gen Virol. 83:2833-2844.
  • Smith GL; Vanderplasschen A; Law M. (Dec 2002). The formation and function of extracellular enveloped vaccinia virus. J Gen Virol. 83:2915-2931.
  • Smith GL; Murphy BJ; Law M. (2003). Vaccinia virus motility. Annu Rev Microbiol. 57:323-342. DOI.
  • Reading PC; Symons JA; Smith GL. (1 Feb 2003). A soluble chemokine-binding protein from vaccinia virus reduces virus virulence and the inflammatory response to infection. J Immunol. 170:1435-1442.
  • Harte MT; Haga IR; Maloney G; Gray P; Reading PC; Bartlett NW; Smith GL; Bowie A; et alO'Neill LA. (3 Feb 2003). The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense. J Exp Med. 197:343-351.
  • Reading PC; Moore JB; Smith GL. (19 May 2003). Steroid hormone synthesis by vaccinia virus suppresses the inflammatory response to infection. J Exp Med. 197:1269-1278. DOI.
  • McConkey SJ; Reece WH; Moorthy VS; Webster D; Dunachie S; Butcher G; Vuola JM; Blanchard TJ; et alGothard P; Watkins K; Hannan CM; Everaere S; Brown K; Kester KE; Cummings J; Williams J; Heppner DG; Pathan A; Flanagan K; Arulanantham N; Roberts MT; Roy M; Smith GL; Schneider J; Peto T; Sinden RE; Gilbert SC; Hill AV. (Jun 2003). Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans. Nat Med. 9:729-735. DOI.
  • Reading PC; Smith GL. (Aug 2003). A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection. J Gen Virol. 84:1973-1983.
  • Carter GC; Rodger G; Murphy BJ; Law M; Krauss O; Hollinshead M; Smith GL. (Sep 2003). Vaccinia virus cores are transported on microtubules. J Gen Virol. 84:2443-2458.
  • Pires de Miranda M; Reading PC; Tscharke DC; Murphy BJ; Smith GL. (Sep 2003). The vaccinia virus kelch-like protein C2L affects calcium-independent adhesion to the extracellular matrix and inflammation in a murine intradermal model. J Gen Virol. 84:2459-2471.
  • Reading PC; Smith GL. (Sep 2003). Vaccinia virus interleukin-18-binding protein promotes virulence by reducing gamma interferon production and natural killer and T-cell activity. J Virol. 77:9960-9968.
  • Najarro P; Lee HJ; Fox J; Pease J; Smith GL. (Dec 2003). Yaba-like disease virus protein 7L is a cell-surface receptor for chemokine CCL1. J Gen Virol. 84:3325-3336.
  • Law M; Smith GL. (2004). Studying the binding and entry of the intracellular and extracellular enveloped forms of vaccinia virus. Methods Mol Biol. 269:187-204. DOI.
  • Gubser C; Hué S; Kellam P; Smith GL. (Jan 2004). Poxvirus genomes: a phylogenetic analysis. J Gen Virol. 85:105-117.
  • Law M; Hollinshead M; Lee HJ; Smith GL. (May 2004). Yaba-like disease virus protein Y144R, a member of the complement control protein family, is present on enveloped virions that are associated with virus-induced actin tails. J Gen Virol. 85:1279-1290.
  • Bartlett NW; Dumoutier L; Renauld JC; Kotenko SV; McVey CE; Lee HJ; Smith GL. (Jun 2004). A new member of the interleukin 10-related cytokine family encoded by a poxvirus. J Gen Virol. 85:1401-1412.
  • Smith GL; Law M. (Dec 2004). The exit of vaccinia virus from infected cells. Virus Res. 106:189-197. DOI.
  • Stack J; Haga IR; Schroder M; Bartlett NW; Maloney G; Reading PC; Fitzgerald KA; Smith GL; et alBowie AG. (21 Mar 2005). Vaccinia virus protein Toll-like-interleukin-1 A46R targets multiple receptor adaptors and contributes to virulence. JOURNAL OF EXPERIMENTAL MEDICINE. 201:1007-1018. Author weblink DOI.
  • Law M; Pütz MM; Smith GL. (Apr 2005). An investigation of the therapeutic value of vaccinia-immune IgG in a mouse pneumonia model. J Gen Virol. 86:991-1000. DOI.
  • Carter GC; Law M; Hollinshead M; Smith GL. (May 2005). Entry of the vaccinia virus intracellular mature virion and its interactions with glycosaminoglycans. J Gen Virol. 86:1279-1290. DOI.
  • Bartlett NW; Buttigieg K; Kotenko SV; Smith GL. (Jun 2005). Murine interferon lambdas (type III interferons) exhibit potent antiviral activity in vivo in a poxvirus infection model. J Gen Virol. 86:1589-1596. DOI.
  • Pütz MM; Alberini I; Midgley CM; Manini I; Montomoli E; Smith GL. (Nov 2005). Prevalence of antibodies to Vaccinia virus after smallpox vaccination in Italy. J Gen Virol. 86:2955-2960. DOI.
  • Herrero-Martínez E; Roberts KL; Hollinshead M; Smith GL. (Nov 2005). Vaccinia virus intracellular enveloped virions move to the cell periphery on microtubules in the absence of the A36R protein. J Gen Virol. 86:2961-2968. DOI.
  • Clark RH; Kenyon JC; Bartlett NW; Tscharke DC; Smith GL. (Jan 2006). Deletion of gene A41L enhances vaccinia virus immunogenicity and vaccine efficacy. J Gen Virol. 87:29-38. DOI.
  • Ait-Tahar K; Cerundolo V; Banham AH; Hatton C; Blanchard T; Kusec R; Becker M; Smith GL; et alPulford K. (1 Feb 2006). B and CTL responses to the ALK protein in patients with ALK-positive ALCL. Int J Cancer. 118:688-695. DOI.
  • Najarro P; Gubser C; Hollinshead M; Fox J; Pease J; Smith GL. (Apr 2006). Yaba-like disease virus chemokine receptor 7L, a CCR8 orthologue. J Gen Virol. 87:809-816. DOI.
  • Law M; Carter GC; Roberts KL; Hollinshead M; Smith GL. (11 Apr 2006). Ligand-induced and nonfusogenic dissolution of a viral membrane. Proc Natl Acad Sci U S A. 103:5989-5994. DOI.
  • Jacobs N; Chen RA; Gubser C; Najarro P; Smith GL. (May 2006). Intradermal immune response after infection with Vaccinia virus. J Gen Virol. 87:1157-1161. DOI.
  • Beard PM; Froggatt GC; Smith GL. (Jun 2006). Vaccinia virus kelch protein A55 is a 64 kDa intracellular factor that affects virus-induced cytopathic effect and the outcome of infection in a murine intradermal model. J Gen Virol. 87:1521-1529. DOI.
  • Chen RA; Jacobs N; Smith GL. (Jun 2006). Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor. J Gen Virol. 87:1451-1458. DOI.
  • Esposito JJ; Sammons SA; Frace AM; Osborne JD; Olsen-Rasmussen M; Zhang M; Govil D; Damon IK; et alKline R; Laker M; Li Y; Smith GL; Meyer H; LeDuc JW; Wohlhueter RM. (11 Aug 2006). Genome sequence diversity and clues to the evolution of variola (smallpox) virus. SCIENCE. 313:807-812. DOI.
  • Pütz MM; Midgley CM; Law M; Smith GL. (Nov 2006). Quantification of antibody responses against multiple antigens of the two infectious forms of Vaccinia virus provides a benchmark for smallpox vaccination. Nat Med. 12:1310-1315. DOI.
  • Fox JM; Najarro P; Smith GL; Struyf S; Proost P; Pease JE. (1 Dec 2006). Structure/function relationships of CCR8 agonists and antagonists. Amino-terminal extension of CCL1 by a single amino acid generates a partial agonist. J Biol Chem. 281:36652-36661. DOI.
  • Gubser C; Bergamaschi D; Hollinshead M; Lu X; van Kuppeveld FJM; Smith GL. (1 Feb 2007). A new inhibitor of apoptosis from vaccinia virus and eukaryotes. PLOS PATHOGENS. 3:246-259. Author weblink DOI.
  • Schoniger S; Chan DL; Hollinshead M; Humm K; Smith GL; Beard PM. (14 Apr 2007). Cowpox virus pneumonia in a domestic cat in Great Britain. VETERINARY RECORD. 160:522-523. Author weblink.
  • Gubser C; Goodbody R; Ecker A; Brady G; O'Neill LAJ; Jacobs N; Smith GL. (1 Jun 2007). Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence. JOURNAL OF GENERAL VIROLOGY. 88:1667-1676. Author weblink DOI.
  • Cooray S; Bahar MW; Abrescia NG; McVey CE; Bartlett NW; Chen RA; Stuart DI; Grimes JM; et alSmith GL. (Jun 2007). Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein. J Gen Virol. 88:1656-1666. DOI.
  • Huang J; Smirnov SV; Lewis-Antes A; Balan M; Li W; Tang S; Silke GV; Putz MM; et alSmith GL; Kotenko SV. (5 Jun 2007). Inhibition of type I and type III interferons by a secreted glycoprotein from Yaba-like disease virus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 104:9822-9827. Author weblink DOI.
  • Froggatt GC; Smith GL; Beard PM. (Jul 2007). Vaccinia virus gene F3L encodes an intracellular protein that affects the innate immune response. J Gen Virol. 88:1917-1921. DOI.
  • Kotenko SV; Huang JV; Smirnov S; Li W; Lewis-Antes A; Balan M; Tang S; Silke GV; et alPuetz MM; Smith GL. (1 Aug 2007). Inhibition of type I and type III interferons by a secreted glycoprotein from Yaba-like disease virus. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. 27:734-734. Author weblink.
  • Graham SC; Bahar MW; Abrescia NG; Smith GL; Stuart DI; Grimes JM. (21 Sep 2007). Structure of CrmE, a virus-encoded tumour necrosis factor receptor. J Mol Biol. 372:660-671. DOI.
  • Bahar MW; Kenyon JC; Putz MM; Abrescia NG; Pease JE; Wise EL; Stuart DI; Smith GL; et alGrimes JM. (Jan 2008). Structure and function of A41, a vaccinia virus chemokine binding protein. PLoS Pathog. 4:e5. DOI.
  • Chen RA; Ryzhakov G; Cooray S; Randow F; Smith GL. (8 Feb 2008). Inhibition of IkappaB kinase by vaccinia virus virulence factor B14. PLoS Pathog. 4:e22. DOI.
  • Graham SC; Bahar MW; Cooray S; Chen RA-J; Whalen DM; Abrescia NGA; Alderton D; Owens RJ; et alStuart DI; Smith GL; Grimes JM. (1 Aug 2008). Vaccinia virus proteins A52 and B14 share a Bcl-2-like fold but have evolved to inhibit NF-kappa B rather than apoptosis. PLOS PATHOGENS. 4. Author weblink DOI.
  • Roberts KL; Smith GL. (1 Oct 2008). Vaccinia virus morphogenesis and dissemination. TRENDS IN MICROBIOLOGY. 16:472-479. Author weblink DOI.
  • Fahy AS; Clark RH; Glyde EF; Smith GL. (Oct 2008). Vaccinia virus protein C16 acts intracellularly to modulate the host response and promote virulence. J Gen Virol. 89:2377-2387. DOI.
  • Lee LY-H; Ha DLA; Simmons C; de Jong MD; Chau NVV; Schumacher R; Peng YC; McMichael AJ; et alFarrar JJ; Smith GL; Townsend ARM; Askonas BA; Rowland-Jones S; Dong T. (1 Oct 2008). Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals. JOURNAL OF CLINICAL INVESTIGATION. 118:3478-3490. Author weblink DOI.
  • Jacobs N; Bartlett NW; Clark RH; Smith GL. (1 Nov 2008). Vaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infection. JOURNAL OF GENERAL VIROLOGY. 89:2877-2881. Author weblink DOI.
  • Midgley CM; Putz MM; Weber JN; Smith GL. (1 Dec 2008). Vaccinia virus strain NYVAC induces substantially lower and qualitatively different human antibody responses compared with strains Lister and Dryvax. JOURNAL OF GENERAL VIROLOGY. 89:2992-2997. Author weblink DOI.
  • Trilling M; Le VT; Zimmermann A; Ludwig H; Pfeffer K; Sutter G; Smith GL; Hengel H. (Apr 2009). Gamma interferon-induced interferon regulatory factor 1-dependent antiviral response inhibits vaccinia virus replication in mouse but not human fibroblasts. J Virol. 83:3684-3695. DOI.
  • Roberts KL; Breiman A; Carter GC; Ewles HA; Hollinshead M; Law M; Smith GL. (Jul 2009). Acidic residues in the membrane-proximal stalk region of vaccinia virus protein B5 are required for glycosaminoglycan-mediated disruption of the extracellular enveloped virus outer membrane. J Gen Virol. 90:1582-1591. DOI.
  • de Mattia F; Gubser C; van Dommelen MMT; Visch H-J; Distelmaier F; Postigo A; Luyten T; Parys JB; et alde Smedt H; Smith GL; Willems PHGM; van Kuppeveld FJM. (15 Aug 2009). Human Golgi Antiapoptotic Protein Modulates Intracellular Calcium Fluxes. MOLECULAR BIOLOGY OF THE CELL. 20:3638-3645. Author weblink DOI.
  • Doceul V; Hollinshead M; van der Linden L; Smith GL. (12 Feb 2010). Repulsion of superinfecting virions: a mechanism for rapid virus spread. Science. 327:873-876. DOI.
  • Morgan GW; Hollinshead M; Ferguson BJ; Murphy BJ; Carpentier DC; Smith GL. (Feb 2010). Vaccinia protein F12 has structural similarity to kinesin light chain and contains a motor binding motif required for virion export. PLoS Pathog. 6:e1000785. DOI Open Access copy.
  • Breiman A; Smith GL. (Jul 2010). Vaccinia virus B5 protein affects the glycosylation, localization and stability of the A34 protein. J Gen Virol. 91:1823-1827. DOI.

Books

  • Smith GL. New challenges to health: the threat of virus infection. -4. (2001).

Chapters in books

  • Smith GL; Beard P; Skinner MA. Poxviruses. In Encyclopedia of Virology. Third. Mahy BWJ (ed); Van Regenmortel MHV (ed). Academic Press (Mar 2008).

Conferences

  • SMITH GL. Vaccinia virus inhibition of host defenses. 3rd Congress of the European-Society-for-Veterinary-Virology on Immunobiology of Viral Infections, 4 Sep 1994 - 7 Sep 1994. 16-23. FONDATION MERIEUX (1 Jan 1995). Author weblink.
  • Gilbert SC; Schneider J; Hannan CM; Plebanski M; Neuman V; Degano P; Blanchard TJ; Becker M; et alSmith GL; Hill AVS. Development of a CTL inducing vaccine against Plasmodium falciparum using a combination of delivery systems. 9th International Congress of Parasitology (ICOPA IX), 24 Aug 1998 - 28 Aug 1998. 439-444. MEDIMOND S R L (1 Jan 1998). Author weblink.
  • Smith GL; Dunn W. Poxvirus chemokine-binding proteins. Euroconference of Institut Pasteur on Chemokines and Their Receptors - From Basic Research to Therapeutic Intervention, 11 Mar 1999 - 13 Mar 1999. 10:288-289. JOHN LIBBEY EUROTEXT LTD (1 Jun 1999). Author weblink.
  • Smith GL; Vanderplasschen A. Vaccinia virus entry and exit. 2nd ICGEB-UCI Virology Symposium, Nov 1998. 25-42. SCIENCE PUBLISHERS INC (1 Jan 2000). Author weblink.
  • Murphy BJ; Carpentier DCJ; Smith GL. Interaction of vaccinia virus F12L protein with components of microtubules. 42nd Annual Meeting of the American-Society-for-Cell-Biology. 13:464A-464A. (Nov 2002).

Patents

  • Methods and reagents for vaccination which generate CD8 T cell immune response. Patent number: 6,663,871 (USA). Awarded: 16 Dec 2003.
  • Recombinant poxviruses having foreign DNA expressed under the control of poxvirus regulatory sequences. Patent number: 6,998,252 (USA). Awarded: 14 Feb 2006.
  • Compositions containing recombinant poxviruses having foreign DNA expressed under the control of poxvirus regulatory sequences. Patent number: 7,015,024 (USA). Awarded: 21 Mar 2006.
  • Methods of immunization using recombinant poxviruses having foreign DNA expressed under the control of poxvirus regulatory sequences. Patent number: 7,045,136 (USA). Awarded: 16 May 2006.
  • Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA. Patent number: 7,045,313 (USA). Awarded: 16 May 2006.
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