Dr Irina Udalova

Dr Irina Udalova

All Publications

Journals

  • Goh FG; Piccinini AM; Krausgruber T; Udalova IA; Midwood KS. (1 Mar 2010). Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation. J Immunol. 184:2655-2662. DOI.
  • Thomson SJP; Goh FG; Banks H; Krausgruber T; Kotenko SV; Foxwell BMJ; Udalova IA. (14 Jul 2009). The role of transposable elements in the regulation of IFN-lambda 1 gene expression. P NATL ACAD SCI USA. 106:11564-11569. DOI.
  • Goh FG; Banks H; Udalova IA. (2009). Detecting and modulating the NF-kB activity in human immune cells: generation of human cell lines with altered levels of NF-kappaB. Methods Mol Biol. 512:39-54. DOI.
  • Thomson S; Udalova IA. (2009). Quantitative measurement of cytokine expression in synoviocytes derived from rheumatoid arthritis patients. Methods Mol Biol. 512:233-248. DOI.
  • Thomson S; Kotenko S; Foxwell B; Udalova I. (Aug 2007). Role for IFN-lambda s in rheumatoid arthritis. J INTERF CYTOK RES. 27:703-703.
  • Copley RR; Totrov M; Linnell J; Field S; Ragoussis J; Udalova IA. (Sep 2007). Functional conservation of Rel binding sites in drosophilid genomes. Genome Res. 17:1327-1335. DOI.
  • Field S; Udalova I; Ragoussis J. (2007). Accuracy and reproducibility of protein-DNA microarray technology. Adv Biochem Eng Biotechnol. 104:87-110.
  • Forton JT; Udalova IA; Campino S; Rockett KA; Hull J; Kwiatkowski DP. (Jan 2007). Localization of a long-range cis-regulatory element of IL13 by allelic transcript ratio mapping. Genome Res. 17:82-87. DOI.
  • Koch O; Kwiatkowski DP; Udalova IA. (1 May 2006). Context-specific functional effects of IFNGR1 promoter polymorphism. Hum Mol Genet. 15:1475-1481. DOI.
  • Hanchard N; Rockett K; Udalova I; Wilson J; Keating B; Koch O; Nijnik A; Diakite M; et al. (Jan 2006). An investigation of transmission ratio distortion in the central region of the human MHC. Genes Immun. 7:51-58. DOI.
  • Hacking D; Knight JC; Rockett K; Brown H; Frampton J; Kwiatkowski DP; Hull J; Udalova IA. (Jun 2004). Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility. Genes Immun. 5:274-282. DOI.
  • Linnell J; Mott R; Field S; Kwiatkowski DP; Ragoussis J; Udalova IA. (Feb 2004). Quantitative high-throughput analysis of transcription factor binding specificities. NUCLEIC ACIDS RES. 32. DOI.
  • Nijnik A; Mott R; Kwiatkowski DP; Udalova IA. (1 Mar 2003). Comparing the fine specificity of DNA binding by NF-kappaB p50 and p52 using principal coordinates analysis. Nucleic Acids Res. 31:1497-1501.
  • Udalova IA; Mott R; Field D; Kwiatkowski D. (11 Jun 2002). Quantitative prediction of NF-kappa B DNA-protein interactions. Proc Natl Acad Sci U S A. 99:8167-8172. DOI.
  • Udalova IA; Richardson A; Ackerman H; Wordsworth P; Kwiatkowski D. (Jul 2002). Association of accelerated erosive rheumatoid arthritis with a polymorphism that alters NF-kappa B binding to the TNF promoter region. RHEUMATOLOGY. 41:830-U5.
  • Ackerman H; Udalova I; Hull J; Kwiatkowski D. (Jun 2002). Evolution of a polymorphic regulatory element in interferon-gamma through transposition and mutation. Mol Biol Evol. 19:884-890.
  • van Heel DA; Udalova IA; De Silva AP; McGovern DP; Kinouchi Y; Hull J; Lench NJ; Cardon LR; et al. (15 May 2002). Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. Hum Mol Genet. 11:1281-1289.
  • van Heel DA; Udalova IA; De Silva AP; McGovern DP; Kinouchi Y; Hull J; Lench NJ; Cardon LR; et al. (Apr 2002). Inflammatory bowel disease is associated with functional TNF polymorphism affecting OCT1/NF-kappa B interaction. GUT. 50:A30-A30.
  • Denys A; Udalova IA; Smith C; Williams LM; Ciesielski CJ; Campbell J; Andrews C; Kwaitkowski D; et al. (15 May 2002). Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophages. J Immunol. 168:4837-4845.
  • Udalova IA; Kwiatkowski D. (23 Nov 2001). Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region. Biochem Biophys Res Commun. 289:25-33. DOI.
  • Udalova IA; Richardson A; Denys A; Smith C; Ackerman H; Foxwell B; Kwiatkowski D. (Dec 2000). Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region. Mol Cell Biol. 20:9113-9119.
  • Udalova IA; Vidal V; Scragg IG; Kwiatkowski D. (Sep 2000). Direct evidence for involvement of NF-kappaB in transcriptional activation of tumor necrosis factor by a spirochetal lipoprotein. Infect Immun. 68:5447-5449.
  • Kuprash DV; Udalova IA; Turetskaya RL; Kwiatkowski D; Rice NR; Nedospasov SA. (1 Apr 1999). Similarities and differences between human and murine TNF promoters in their response to lipopolysaccharide. J IMMUNOL. 162:4045-4052.
  • Knight JC; Udalova I; Hill AV; Greenwood BM; Peshu N; Marsh K; Kwiatkowski D. (Jun 1999). A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat Genet. 22:145-150. DOI.
  • Udalova IA; Knight JC; Vidal V; Nedospasov SA; Kwiatkowski D. (14 Aug 1998). Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes. J Biol Chem. 273:21178-21186.

Chapters in books

  • Andreakos E; Udalova IA; Sacre S. The role of NF-kappaB in inflammatory diseases. In Nuclear Factor kappaB. Regulation and Role in Disease. 297-325. Beyaert R (ed). Kluwer Academic Publishers, Netherlands (2003).
  • Ragoussis J; Field S; Udalova IA. Quantitative Profiling of Protein-DNA Binding on Microarrays. In Methods in Molecular Biology, vol. 338: Gene Mapping, Discovery, and Expression: Methods and Protocols. Bina M (ed). Humana Press Inc, USA (2005).

Conferences

  • Goh F; Thomson SJP; Udalova IA. Examining the role of nuclear factor kappa-B proteins in human cytokine gene expression: Comparison of type I and type III interferons. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, 12 Oct 2008 - 16 Oct 2008. 43:315-315. ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD (Sep 2008). DOI.
  • Krausgrube T; Thomson SJP; Saliba DG; Udalova IA. Role of interferon regulatory factor 5 in regulation of the human tumor necrosis factor gene expression. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, 12 Oct 2008 - 16 Oct 2008. 43:313-313. ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD (Sep 2008). DOI.
  • Thomson SJP; Goh F; Banks H; Foxwell B; Kotenko SV; Udalova IA. Identification of a novel enhancer region in the distal promoter region of the human interferon-lambda1 gene. 7th Joint Conference of the International-Cytokine-Society/International-Society-for-Interferon-and-Cytoklin-Research, 12 Oct 2008 - 16 Oct 2008. 43:281-281. ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD (Sep 2008). DOI.
  • Vagenas P; Clark JM; Testar J; Panesar M; Udalova I; Freeman T; Lyons P; Cope AP. Engagement of the p55 TNF-R for different periods of time induces qualitatively distinct pathways of tumour necrosis factor signalling and gene expression profiles in murine T cells. 25th European Workshop for Rheumatology Research, 24 Feb 2005 - 27 Feb 2005. 7:S27-S27. BIOMED CENTRAL LTD (Feb 2005). DOI.
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