Professor Jane A Mitchell

Publications


Journals

  • Wojciak-Stothard B; Zhao L; Oliver E; Dubois O; Wu Y; Kardassis D; Vasilaki E; Huang M; et alMitchell JA; Louise H; Prendergas GC; Wilkins MR. (26 Apr 2012). Role of RhoB in the Regulation of Pulmonary Endothelial and Smooth Muscle Cell Responses to Hypoxia. Circ Res. DOI.
  • George PM; Badiger R; Alazawi W; Foster GR; Mitchell JA. (28 Mar 2012). Pharmacology and therapeutic potential of interferons. Pharmacol Ther. DOI.
  • Wright WR; Parzych K; Crawford D; Mein C; Mitchell JA; Paul-Clark MJ. (2012). Inflammatory transcriptome profiling of human monocytes exposed acutely to cigarette smoke. PLoS One. 7:e30120. DOI.
  • Potter CM; Schobesberger S; Lundberg MH; Weinberg PD; Mitchell JA; Gorelik J. (2012). Shape and compliance of endothelial cells after shear stress in vitro or from different aortic regions: scanning ion conductance microscopy study. PLoS One. 7:e31228. DOI.
  • Kirkby NS; Leadbeater PD; Chan MV; Nylander S; Mitchell JA; Warner TD. (Oct 2011). 22 Inhibition Of ADP- and thromboxane-dependent pathways of platelet aggregation by The P2Y12 antagonists, ticagrelor and prasugrel. Heart. 97:e7. DOI.
  • Leadbeater PD; Kirkby NS; Thomas S; Dhanji AR; Tucker AT; Milne GL; Mitchell JA; Warner TD. (Oct 2011). 46 Urinary prostanoid metabolites in healthy volunteers taking prasugrel and aspirin. Heart. 97:e7. DOI.
  • Reed DM; Foldes G; Badiger RV; Ali NN; Wheeler-Jones CP; Paul-Clark MJ; Harding SE; Mitchell JA. (1 Oct 2011). TLR3 AND INTERFERON FUNCTION IN HUMAN EMBRYONIC STEM CELL-DERIVED ENDOTHELIAL CELLS (HESC-EC): RELEVANCE TO VIRAL IMMUNITY. HEART. 97:12-12. Author weblink DOI.
  • Pathan N; Burmester M; Adamovic T; Berk M; Ng KW; Betts H; Macrae D; Waddell S; et alPaul-Clark M; Nuamah R; Mein C; Levin M; Montana G; Mitchell JA. (1 Dec 2011). Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease. Am J Respir Crit Care Med. 184:1261-1269. DOI.
  • Kirkby NS; Leadbeater PD; Chan MV; Nylander S; Mitchell JA; Warner TD. (Oct 2011). Antiplatelet effects of aspirin vary with level of P2Y₁₂ receptor blockade supplied by either ticagrelor or prasugrel. J Thromb Haemost. 9:2103-2105. DOI.
  • Leadbeater PD; Kirkby NS; Thomas S; Dhanji AR; Tucker AT; Milne GL; Mitchell JA; Warner TD. (Oct 2011). Aspirin has little additional anti-platelet effect in healthy volunteers receiving prasugrel. J Thromb Haemost. 9:2050-2056. DOI.
  • Harrington LS; Lundberg MH; Waight M; Rozario A; Mitchell JA. (20 May 2011). Reduced endothelial dependent vasodilation in vessels from TLR4(-/-) mice is associated with increased superoxide generation. Biochem Biophys Res Commun. 408:511-515. DOI.
  • Miragoli M; Moshkov A; Novak P; Shevchuk A; Nikolaev VO; El-Hamamsy I; Potter CM; Wright P; et alKadir SH; Lyon AR; Mitchell JA; Chester AH; Klenerman D; Lab MJ; Korchev YE; Harding SE; Gorelik J. (6 Jul 2011). Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells. J R Soc Interface. 8:913-925. DOI.
  • Foldes G; Ali NN; Randi A; Starke R; Paschalaki K; Gatheral T; Harding SE; Mitchell JA. (1 Jan 2011). PATHOGEN SENSING PATHWAYS IN HUMAN STEM CELL-DERIVED ENDOTHELIAL CELLS. SHOCK. 36:4-4. Author weblink.
  • Armstrong PC; Kirkby NS; Zain ZN; Emerson M; Mitchell JA; Warner TD. (2011). Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse. PLoS One. 6:e20062. DOI.
  • Armstrong PC; Leadbeater PD; Chan MV; Kirkby NS; Jakubowski JA; Mitchell JA; Warner TD. (Mar 2011). In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation. J Thromb Haemost. 9:552-561. DOI.
  • Potter CM; Lundberg MH; Harrington LS; Warboys CM; Warner TD; Berson RE; Moshkov AV; Gorelik J; et alWeinberg PD; Mitchell JA. (Feb 2011). Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms. Arterioscler Thromb Vasc Biol. 31:384-391. DOI.
  • Cartwright N; Noulin N; Couillin L; Quesniaux V; Ryffel B; Mitchell JA. (23 Nov 2010). Macrophage Sensing of Lps in vivo is Not Required for the Induction of Systemic Inflammation. CIRCULATION. 122. Author weblink.
  • Warner TD; Armstrong PCJ; Curzen NP; Mitchell JA. (1 Nov 2010). Dual antiplatelet therapy in cardiovascular disease: does aspirin increase clinical risk in the presence of potent P2Y(12) receptor antagonists?. HEART. 96:1693-1694. DOI.
  • Moreno L; McMaster SK; Gatheral T; Bailey LK; Harrington LS; Cartwright N; Armstrong PC; Warner TD; et alPaul-Clark M; Mitchell JA. (Aug 2010). Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages. Br J Pharmacol. 160:1997-2007. DOI.
  • Hansel TT; Kropshofer H; Singer T; Mitchell JA; George AJ. (Apr 2010). The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov. 9:325-338. DOI.
  • Armstrong PCJ; Dhanji A-RA; Tucker AT; Mitchell JA; Warner TD. (1 Mar 2010). Reduction of platelet thromboxane A(2) production ex vivo and in vivo by clopidogrel therapy. JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 8:613-615. Author weblink DOI.
  • Földes G; Liu A; Badiger R; Paul-Clark M; Moreno L; Lendvai Z; Wright JS; Ali NN; et alHarding SE; Mitchell JA. (2010). Innate immunity in human embryonic stem cells: comparison with adult human endothelial cells. PLoS One. 5:e10501. DOI.
  • Harrington LS; Moreno L; Reed A; Wort SJ; Desvergne B; Garland C; Zhao L; Mitchell JA. (2010). The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension. PLoS One. 5:e9526. DOI.
  • Ali FY; Hall MG; Desvergne B; Warner TD; Mitchell JA. (Nov 2009). PPARbeta/delta agonists modulate platelet function via a mechanism involving PPAR receptors and specific association/repression of PKCalpha--brief report. Arterioscler Thromb Vasc Biol. 29:1871-1873. DOI.
  • Belvisi MG; Mitchell JA. (Oct 2009). Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease. Br J Pharmacol. 158:994-1003. DOI.
  • Armstrong PCJ; Dhanji A-R; Truss NJ; Zain ZNM; Tucker AT; Mitchell JA; Warner TD. (1 Oct 2009). Utility of 96-well plate aggregometry and measurement of thrombi adhesion to determine aspirin and clopidogrel effectiveness. THROMBOSIS AND HAEMOSTASIS. 102:772-778. Author weblink DOI.
  • Wort SJ; Ito M; Chou P-C; Mc Master SK; Badiger R; Jazrawi E; de Souza P; Evans TW; et alMitchell JA; Pinhu L; Ito K; Adcock IM. (4 Sep 2009). Synergistic Induction of Endothelin-1 by Tumor Necrosis Factor alpha and Interferon gamma Is due to Enhanced NF-kappa B Binding and Histone Acetylation at Specific kappa B Sites. JOURNAL OF BIOLOGICAL CHEMISTRY. 284:24297-24305. Author weblink DOI.
  • Piqueras L; Sanz MJ; Perretti M; Morcillo E; Norling L; Mitchell JA; Li Y; Bishop-Bailey D. (Jul 2009). Activation of PPARbeta/delta inhibits leukocyte recruitment, cell adhesion molecule expression, and chemokine release. J Leukoc Biol. 86:115-122. DOI.
  • Secher T; Vasseur V; Poisson DM; Mitchell JA; Cunha FQ; Alves-Filho JC; Ryffel B. (15 Jun 2009). Crucial Role of TNF Receptors 1 and 2 in the Control of Polymicrobial Sepsis. JOURNAL OF IMMUNOLOGY. 182:7855-7864. Author weblink DOI.
  • Ali FY; Armstrong PCJ; Dhanji A-RA; Tucker AT; Paul-Clark MJ; Mitchell JA; Warner TD. (1 May 2009). Antiplatelet Actions of Statins and Fibrates Are Mediated by PPARs. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 29:706-711. Author weblink DOI.
  • Paul-Clark MJ; McMaster SK; Sorrentino R; Sriskandan S; Bailey LK; Moreno L; Ryffel B; Quesniaux VF; et alMitchell JA. (15 Feb 2009). Toll-like receptor 2 is essential for the sensing of oxidants during inflammation. Am J Respir Crit Care Med. 179:299-306. DOI.
  • Armstrong PCJ; Truss NJ; Ali FY; Dhanji AA; Vojnovic I; Zain ZNM; Bishop-Bailey D; Paul-Clark MJ; et alTucker AT; Mitchell JA; Warner TD. (1 Nov 2008). Aspirin and the in vitro linear relationship between thromboxane A(2)-mediated platelet aggregation and platelet production of thromboxane A(2). JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 6:1933-1943. Author weblink DOI.
  • Harrington LS; Lucas R; McMaster SK; Moreno L; Scadding G; Warner TD; Mitchell JA. (1 Nov 2008). COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma. FASEB JOURNAL. 22:4005-4010. Author weblink DOI.
  • Ali FY; Warner TD; Mitchell JA. (1 Sep 2008). Comparison of responses in IP and PPAR beta deleted murine platelets. HEART. 94. Author weblink.
  • Zain ZNM; Armstrong PCJ; Pearson NJ; Mitchell JA; Warner TD. (1 Sep 2008). Evaluation of aspirin inhibition of platelet aggregation induced by combination of collagen and adrenaline in a 96-well plate format. HEART. 94. Author weblink.
  • Dhanji AA; Truss NJ; Bishop-Bailey D; Shipolini A; Mitchell JA; Warner TD. (1 Sep 2008). Generation of clonal populations of prostaglandin I(2)-producing rat vascular smooth muscle cells: Potential utility for production of bypass vessels. HEART. 94. Author weblink.
  • Armstrong PCJ; Zain ZNM; Truss NJ; Vojnovic I; Bishop-Bailey D; Mitchell JA; Warner TD. (1 Sep 2008). Linear relationship between platelet aggregation and thromboxane A(2) production. HEART. 94. Author weblink.
  • Moreno L; Bailey LK; Cartwright N; Paul-Clark M; Mitchell JA. (1 Aug 2008). Rip2 mediates NOSII-induction by NOD1 activation in vascular smooth muscle cells but not by TLR4 activation in macrophages. FUNDAMENTAL & CLINICAL PHARMACOLOGY. 22:86-87. Author weblink.
  • Moreno L; McMaster SK; Paul-Clark M; Harrington L; Cartwright N; Secher T; Quesniaux V; Ryffel B; et alMitchell JA. (1 Aug 2008). The PPAR target gene CD36 is a rate limiting factor for the sensing of gram positive S-aureus in vascular smooth muscle cells but not in macrophages. FUNDAMENTAL & CLINICAL PHARMACOLOGY. 22:48-48. Author weblink.
  • Sorrentino R; de Souza PM; Sriskandan S; Duffin C; Paul-Clark MJ; Mitchell JA. (Jun 2008). Pattern recognition receptors and interleukin-8 mediate effects of Gram-positive and Gram-negative bacteria on lung epithelial cell function. Br J Pharmacol. 154:864-871. DOI.
  • Paul-Clark MJ; Sorrentino R; Bailey LK; Sriskandan S; Mitchell JA. (May 2008). Gram-positive and Gram-negative bacteria synergize with oxidants to release CXCL8 from innate immune cells. Mol Med. 14:238-246. DOI.
  • Issa R; Sorrentino R; Sukkar MB; Sriskandan S; Chung KF; Mitchell JA. (1 Apr 2008). Differential regulation of CCL-II/eotaxin-I and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells. RESPIRATORY RESEARCH. 9. Author weblink DOI.
  • McMaster SK; Paul-Clark MJ; Walters M; Fleet M; Anandarajah J; Sriskandan S; Mitchell JA. (Feb 2008). Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress. Br J Pharmacol. 153:536-543. DOI.
  • Warner TD; Mitchell JA. (19 Jan 2008). COX-2 selectivity alone does not define the cardiovascular risks associated with non-steroidal anti-inflammatory drugs. LANCET. 371:270-273. Author weblink DOI.
  • Mitchell JA; Ali F; Bailey L; Moreno L; Harrington LS. (1 Jan 2008). Role of nitric oxide and prostacyclin as vasoactive hormones released by the endothelium. EXPERIMENTAL PHYSIOLOGY. 93:141-147. Author weblink DOI.
  • Harrington LS; Belcher E; Moreno L; Carrier MJ; Mitchell JA. (Dec 2007). Homeostatic role of Toll-like receptor 4 in the endothelium and heart. J Cardiovasc Pharmacol Ther. 12:322-326. DOI.
  • Mitchell JA; Ryffel B; Quesniaux VF; Cartwright N; Paul-Clark M. (Dec 2007). Role of pattern-recognition receptors in cardiovascular health and disease. Biochem Soc Trans. 35:1449-1452. DOI.
  • Harrington LS; Evans RJ; Wray J; Norling L; Swales KE; Vial C; Ali F; Carrier MJ; et alMitchell JA. (Nov 2007). Purinergic 2X1 receptors mediate endothelial dependent vasodilation to ATP. Mol Pharmacol. 72:1132-1136. DOI.
  • Patel TA; Belcher E; Warner TD; Harding SE; Mitchell JA. (1 Oct 2007). Identification and characterization of a dysfunctional cardiac myocyte phenotype: Role of bacteria, toll-like receptors, and endothelin. SHOCK. 28:434-440. Author weblink DOI.
  • Williams AS; Leung S-Y; Nath P; Khorasani NM; Bhavsar P; Issa R; Mitchell JA; Adcock IM; et alChung KF. (1 Oct 2007). Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia. JOURNAL OF APPLIED PHYSIOLOGY. 103:1189-1195. Author weblink DOI.
  • Harrington LS; Carrier MJ; Gallagher N; Gilroy D; Garland CJ; Mitchell JA. (Sep 2007). Elucidation of the temporal relationship between endothelial-derived NO and EDHF in mesenteric vessels. Am J Physiol Heart Circ Physiol. 293:H1682-H1688. DOI.
  • Faro R; Moreno L; Hislop AA; Sturton G; Mitchell JA. (19 Jul 2007). Pulmonary endothelium dependent vasodilation emergres after birth in mice. EUROPEAN JOURNAL OF PHARMACOLOGY. 567:240-244. Author weblink DOI.
  • Mitchell JA; Paul-Clark MJ; Clarke GW; McMaster SK; Cartwright N. (1 Jun 2007). Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease. JOURNAL OF ENDOCRINOLOGY. 193:323-330. Author weblink DOI.
  • Cartwright N; Murch O; McMaster SK; Paul-Clark MJ; van Heel DA; Ryffel B; Quesniaux VF; Evans TW; et alThiemermann C; Mitchell JA. (15 Mar 2007). Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. Am J Respir Crit Care Med. 175:595-603. DOI.
  • Cartwright N; McMaster SK; Sorrentino R; Paul-Clark M; Sriskandan S; Ryffel B; Quesniaux VF; Evans TW; et alMitchell JA. (Jan 2007). Elucidation of toll-like receptor and adapter protein signaling in vascular dysfunction induced by gram-positive Staphylococcus aureus or gram-negative Escherichia coli. Shock. 27:40-47. DOI.
  • Mitchell JA; Lucas R; Vojnovic I; Hasan K; Pepper JR; Warner TD. (Dec 2006). Stronger inhibition by nonsteroid anti-inflammatory drugs of cyclooxygenase-1 in endothelial cells than platelets offers an explanation for increased risk of thrombotic events. FASEB J. 20:2468-2475. DOI.
  • Moreno L; Perez-Vizcaino F; Harrington L; Faro R; Sturton G; Barnes PJ; Mitchell JA. (2006). Pharmacology of airways and vessels in lung slices in situ: role of endogenous dilator hormones. Respir Res. 7:111. DOI.
  • Perez-Vizcaino F; Bishop-Bailley D; Lodi F; Duarte J; Cogolludo A; Moreno L; Bosca L; Mitchell JA; et alWarner TD. (4 Aug 2006). The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 346:919-925. Author weblink DOI.
  • Paul-Clark MJ; McMaster SK; Belcher E; Sorrentino R; Anandarajah J; Fleet M; Sriskandan S; Mitchell JA. (Aug 2006). Differential effects of Gram-positive versus Gram-negative bacteria on NOSII and TNFalpha in macrophages: role of TLRs in synergy between the two. Br J Pharmacol. 148:1067-1075. DOI.
  • Mitchell JA; Fitzgerald KA; Coyle A; Silverman N; Cartwright N. (Jul 2006). TOLLing away in Brazil. Nat Immunol. 7:675-679. DOI.
  • Bishop-Bailey D; Mitchell JA; Warner TD. (1 May 2006). COX-2 in cardiovascular disease. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 26:956-958. Author weblink DOI.
  • Ali FY; Davidson SJ; Moraes LA; Traves SL; Paul-Clark M; Bishop-Bailey D; Warner TD; Mitchell JA. (1 Feb 2006). Role of nuclear receptor signaling in platelets: antithrombotic effects of PPAR beta. FASEB JOURNAL. 20:326-328. DOI.
  • Ali FY; Davidson SJ; Moraes LA; Traves SL; Paul-Clark M; Bishop-Bailey D; Warner TD; Mitchell JA. (Feb 2006). Role of nuclear receptor signaling in platelets: antithrombotic effects of PPARbeta. FASEB J. 20:326-328. DOI.
  • Ali FY; Egan K; FitzGerald GA; Desvergne B; Wahli W; Bishop-Bailey D; Warner TD; Mitchell JA. (Feb 2006). Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts. Am J Respir Cell Mol Biol. 34:242-246. DOI.
  • Mitchell JA; Warner TD. (Jan 2006). COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs. Nat Rev Drug Discov. 5:75-86. DOI.
  • Warner TD; Vojnovic I; Bishop-Bailey D; Mitchell JA. (1 Jan 2006). Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and-2. FASEB JOURNAL. 20:542-+. Author weblink DOI.
  • Walters MJ; Paul-Clark MJ; McMaster SK; Ito K; Adcock IM; Mitchell JA. (Nov 2005). Cigarette smoke activates human monocytes by an oxidant-AP-1 signaling pathway: implications for steroid resistance. Mol Pharmacol. 68:1343-1353. DOI.
  • Jimenez R; Belcher E; Sriskandan S; Lucas R; McMaster S; Vojnovic I; Warner TD; Mitchell JA. (22 Mar 2005). Role of Toll-like receptors 2 and 4 in the induction of cyclooxygenase-2 in vascular smooth muscle. Proc Natl Acad Sci U S A. 102:4637-4642. DOI.
  • Harrington LS; Mitchell JA. (Mar 2005). P2X(1) receptors and the endothelium. MEM I OSWALDO CRUZ. 100:111-112.
  • Lucas R; Warner TD; Vojnovic I; Mitchell JA. (1 Feb 2005). Cellular mechanisms of acetaminophen: role of cyclooxygenase. FASEB JOURNAL. 19:635-+. Author weblink DOI.
  • Stanford SJ; Hislop AA; Oltmanns U; Nabel EG; Sang H; Haworth SG; Mitchell JA. (Feb 2005). Transition from placental to air breathing stimulates haem-oxygenase-1 expression without functional consequence for pulmonary vascular adaptation in pigs and mice. Br J Pharmacol. 144:467-476. DOI.
  • Oltmanns U; Chung KF; Walters M; John M; Mitchell JA. (2005). Cigarette smoke induces IL-8, but inhibits eotaxin and RANTES release from airway smooth muscle. Respir Res. 6:74. DOI.
  • Harrington LS; Falck JR; Mitchell JA. (15 Dec 2004). Not so EEZE: the 'EDHF' antagonist 14, 15 epoxyeicosa-5(Z)-enoic acid has vasodilator properties in mesenteric arteries. Eur J Pharmacol. 506:165-168. DOI.
  • Harrington LS; Mitchell JA. (Nov 2004). Novel role for P2X receptor activation in endothelium-dependent vasodilation. Br J Pharmacol. 143:611-617. DOI.
  • Osborne CS; Chakalova L; Brown KE; Carter D; Horton A; Debrand E; Goyenechea B; Mitchell JA; et alLopes S; Reik W; Fraser P. (1 Oct 2004). Active genes dynamically colocalize to shared sites of ongoing transcription. NATURE GENETICS. 36:1065-1071. Author weblink DOI.
  • Warner TD; Vojnovic I; Giuliano F; Jiménez R; Bishop-Bailey D; Mitchell JA. (Aug 2004). Cyclooxygenases 1, 2, and 3 and the production of prostaglandin I2: investigating the activities of acetaminophen and cyclooxygenase-2-selective inhibitors in rat tissues. J Pharmacol Exp Ther. 310:642-647. DOI.
  • Warner TD; Mitchell JA. (May 2004). Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic. FASEB J. 18:790-804. DOI.
  • Stanford SJ; Walters MJ; Mitchell JA. (23 Feb 2004). Carbon monoxide inhibits endothelin-1 release by human pulmonary artery smooth muscle cells. Eur J Pharmacol. 486:349-352. DOI.
  • Warner TD; Mitchell JA. (Oct 2003). HIF, stretching to get control of VEGF. Clin Sci (Lond). 105:393-394. DOI.
  • Woods M; Wood EG; Bardswell SC; Bishop-Bailey D; Barker S; Wort SJ; Mitchell JA; Warner TD. (Oct 2003). Role for nuclear factor-kappaB and signal transducer and activator of transcription 1/interferon regulatory factor-1 in cytokine-induced endothelin-1 release in human vascular smooth muscle cells. Mol Pharmacol. 64:923-931. DOI.
  • Warner TD; Mitchell JA. (5 Aug 2003). Nonsteroidal antiinflammatory drugs inhibiting prostanoid efflux: as easy as ABC?. Proc Natl Acad Sci U S A. 100:9108-9110. DOI.
  • Stanford SJ; Walters MJ; Hislop AA; Haworth SG; Evans TW; Mann BE; Motterlini R; Mitchell JA. (25 Jul 2003). Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role. Eur J Pharmacol. 473:135-141.
  • Price S; Mitchell JA; Anning PB; Evans TW. (4 Jul 2003). Type II nitric oxide synthase activity is cardio-protective in experimental sepsis. Eur J Pharmacol. 472:111-118.
  • Mistry H; Gitlin JM; Mitchell JA; Hiley CR. (Jun 2003). Endothelium-dependent relaxation and endothelial hyperpolarization by P2Y receptor agonists in rat-isolated mesenteric artery. Br J Pharmacol. 139:661-671. DOI.
  • Patel HJ; Belvisi MG; Bishop-Bailey D; Yacoub MH; Mitchell JA. (1 Mar 2003). Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. J Immunol. 170:2663-2669.
  • Gray PA; Warner TD; Vojnovic I; Del Soldato P; Parikh A; Scadding GK; Mitchell JA. (Dec 2002). Effects of non-steroidal anti-inflammatory drugs on cyclo-oxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors. Br J Pharmacol. 137:1031-1038. DOI.
  • Calatayud S; Warner TD; Breese EJ; Mitchell JA. (24 Nov 2002). Modulation by colony stimulating factors of human epithelial colon cancer cell apoptosis. Cytokine. 20:163-167.
  • Warner TD; Mitchell JA; Vane JR. (23 Nov 2002). Cyclo-oxygenase-2 inhibitors and cardiovascular events. Lancet. 360:1700-1701. DOI.
  • Wort SJ; Woods M; Warner TD; Evans TW; Mitchell JA. (Nov 2002). Cyclooxygenase-2 acts as an endogenous brake on endothelin-1 release by human pulmonary artery smooth muscle cells: implications for pulmonary hypertension. Mol Pharmacol. 62:1147-1153.
  • Warner TD; Mitchell JA. (15 Oct 2002). Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?. Proc Natl Acad Sci U S A. 99:13371-13373. DOI.
  • Price S; Evans TW; Mitchell JA. (9 Aug 2002). Nitric oxide supports atrial function in sepsis: relevance to side effects of inhibitors in shock. Eur J Pharmacol. 449:279-285.
  • Mitchell JA; Lye SJ. (Jul 2002). Differential expression of activator protein-1 transcription factors in pregnant rat myometrium. Biol Reprod. 67:240-246.
  • Belcher E; Mitchell J; Evans T. (Jun 2002). Myocardial dysfunction in sepsis: no role for NO?. Heart. 87:507-509.
  • Calatayud S; Warner TD; Mitchell JA. (22 Apr 2002). Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs. Br J Cancer. 86:1316-1321. DOI.
  • Calatayud S; Mitchell JA; Perretti M; Giuliano F; Warner TD. (5 Apr 2002). Effects of cyclooxygenase-1/cyclooxygenase-2 inhibition on leukocyte/endothelial cell interactions in the rat mesentery. Eur J Pharmacol. 440:71-77.
  • Parikh A; Scadding GK; Gray P; Belvisi MG; Mitchell JA. (Apr 2002). High levels of nitric oxide synthase activity are associated with nasal polyp tissue from aspirin-sensitive asthmatics. Acta Otolaryngol. 122:302-305.
  • Woods M; Wood EG; Mitchell JA; Bishop-Bailey D; Warner TD. (1 Mar 2002). Antisense to STAT1/IRF-1 and NF-kappa B inhibits cytokine-stimulated ET-1 release from human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • McCluskie K; Birrell MA; Yacoub MH; Mitchell JA; Belvisi MG. (1 Mar 2002). The role of nitric oxide synthase in antigen-induced airway eosinophilia in the rat. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Gitlin JM; Zanesco A; Stanford SJ; Evans TW; Anning PB; Mitchell JA. (1 Mar 2002). The second phase of ATP mediated relaxation is mediated through P2Y11 receptors. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Arrigoni FI; Hislop AA; Pollock JS; Haworth SG; Mitchell JA. (22 Feb 2002). Birth upregulates nitric oxide synthase activity in the porcine lung. Life Sci. 70:1609-1620.
  • Stanford SJ; Pepper JR; Mitchell JA. (2 Feb 2002). Cytokine modulation of granulocyte macrophage-CSF and granulocyte-CSF release from stimulated vascular smooth muscle cells. Eur J Pharmacol. 436:241-244.
  • Gray PA; Vojnovic I; Del Soldato P; Mitchell JA; Warner TD. (1 Feb 2002). Effects of plasma proteins and blood elements on the potencies of flurbiprofen and NO-flurbiprofen as inhibitors of thromboxane A(2) formation by human platelets. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Bodenreider O; Mitchell JA; McCray AT. (2002). Evaluation of the UMLS as a terminology and knowledge resource for biomedical informatics. Proc AMIA Symp. 61-65.
  • Bishop-Bailey D; Calatayud S; Warner TD; Hla T; Mitchell JA. (2002). Prostaglandins and the regulation of tumor growth. J Environ Pathol Toxicol Oncol. 21:93-101.
  • Lazzeri N; Belvisi MG; Patel HJ; Chung KF; Yacoub MH; Mitchell JA. (21 Dec 2001). RANTES release by human airway smooth muscle: effects of prostaglandin E(2) and fenoterol. Eur J Pharmacol. 433:231-235.
  • Giuliano F; Mitchell JA; Warner TD. (Dec 2001). Sodium salicylate inhibits prostaglandin formation without affecting the induction of cyclooxygenase-2 by bacterial lipopolysaccharide in vivo. J Pharmacol Exp Ther. 299:894-900.
  • Wort SJ; Evans TW; Mitchell JA. (1 Dec 2001). The effect of growth factors on proliferation of human pulmonary artery smooth muscle cells. THORAX. 56:35-36. Author weblink.
  • Gitlin JM; Stanford SJ; Evans TW; Anning PB; Mitchell JA. (1 Nov 2001). ATP induces a biphasic dilator response in mesenteric vessels from Sprague Dawley as well as Wistar rats. BRITISH JOURNAL OF PHARMACOLOGY. 134. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Nov 2001). Cytokine-induced apoptosis of human cultured venous smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 134. Author weblink.
  • Gitlin JM; Stanford SJ; Evans TW; Anning PB; Mitchell JA. (1 Nov 2001). Evidence for the sustained phase of ATP-induced vasodilation being mediated by endothelial derived hyperpolarising factor. BRITISH JOURNAL OF PHARMACOLOGY. 134. Author weblink.
  • Calatayud S; Warner TD; Breese EJ; Mitchell JA. (Nov 2001). Relationship between endogenous colony stimulating factors and apoptosis in human colon cancer cells: role of cyclo-oxygenase inhibitors. Br J Pharmacol. 134:1237-1244. DOI.
  • Gitlin JM; Stanford SJ; Evans TW; Anning PB; Mitchell JA. (1 Nov 2001). The second phase of ATP-evoked relaxation in the isolated rat mesenteric artery bed may be independent of P2Y receptors. BRITISH JOURNAL OF PHARMACOLOGY. 134. Author weblink.
  • Stanford SJ; Pepper JR; Burke-Gaffney A; Mitchell JA. (Aug 2001). Cytokine-activated human vascular smooth muscle delays apoptosis of neutrophils: relevance of interactions between cyclo-oxygenase-2 and colony-stimulating factors. FASEB J. 15:1813-1815.
  • Wort SJ; Woods M; Warner TD; Evans TW; Mitchell JA. (Jul 2001). Endogenously released endothelin-1 from human pulmonary artery smooth muscle promotes cellular proliferation: relevance to pathogenesis of pulmonary hypertension and vascular remodeling. Am J Respir Cell Mol Biol. 25:104-110.
  • Stanford SJ; Gitlin JM; Mitchell JA. (Jul 2001). Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat. Br J Pharmacol. 133:825-832. DOI.
  • Stanford SJ; Pepper JR; Burke-Gaffney A; Mitchell JA. (1 Jun 2001). Cytokine-activated human vascular smooth muscle delays apoptosis of neutrophils: Relevance of interactions between cyclo-oxygenase-2 and colony stimulating factors. FASEB JOURNAL. 15:1813-+. Author weblink DOI.
  • Calatayud S; Allcock GH; Perretti M; Mitchell JA; Warner TD. (1 May 2001). Comparison of the effects of the selective COX-2 inhibitor, DFP, and indomethacin on leukocyte-endothelial cell interactions in the rat mesentery. BRITISH JOURNAL OF PHARMACOLOGY. 133:U102-U102. Author weblink.
  • Bardswell SC; Woods M; Bishop-Bailey D; Wood EG; Mitchell JA; Warner TD. (1 May 2001). Effect of peroxisome proliferator-activated receptor agonists on cytokine-stimulated endothelin-1 production in human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 133:U52-U52. Author weblink.
  • Price S; Mitchell JA; Anning PB. (1 May 2001). Effect of selective iNOS inhibition on cardiac function in endotoxaemia. BRITISH JOURNAL OF PHARMACOLOGY. 133:U4-U4. Author weblink.
  • Wort SJ; Evans TW; Woods M; Warner TD; Mitchell JA. (1 May 2001). Endogenously released endothelin-1 from human pulmonary artery smooth muscle promotes cellular proliferation. BRITISH JOURNAL OF PHARMACOLOGY. 133:U35-U35. Author weblink.
  • Patel HJ; Belvisi MG; Bishop-Bailey D; Yacoub MH; Mitchell JA. (1 May 2001). Evidence for an anti-proliferative role of peroxisome-proliferator-activated receptors in human airway smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 133:U24-U24. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 May 2001). IL-4, but not IFN gamma, differentially regulates GM-CSF and G-CSF release from stimulated arterial and venous smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 133:U23-U23. Author weblink.
  • Gitlin JM; Evans TW; Stanford SJ; Anning PB; Mitchell JA. (1 May 2001). Modulation of anandamide evoked relaxation in the rat isolated mesenteric bed by the PGI(2) analogue cicaprost. BRITISH JOURNAL OF PHARMACOLOGY. 133:U17-U17. Author weblink.
  • Calatayud S; Warner TD; Mitchell JA. (1 May 2001). Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs. BRITISH JOURNAL OF PHARMACOLOGY. 133:U126-U126. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 May 2001). Pre-treatment with IL-1 beta inhibits SNP-induced apoptosis of human venous smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 133:U38-U38. Author weblink.
  • Clarke DL; Patel HJ; Mitchell JA; Yacoub MH; Giembycz MA; Belvisi MG. (1 May 2001). Regulation of the release of colony-stimulating factors from human airway smooth muscle cells by prostaglandin E-2. BRITISH JOURNAL OF PHARMACOLOGY. 133:U23-U23. Author weblink.
  • Gray PA; Breese EJ; Wood EG; Warner TD; Mitchell JA. (1 May 2001). Respective effects of cAMP elevation versus cGMP elevation on GMCSF release by human synoviocytes. BRITISH JOURNAL OF PHARMACOLOGY. 133:U21-U21. Author weblink.
  • Price S; Warner TD; Evans TW; Anning PB; Mitchell JA. (1 May 2001). Role of endothelin-1 in modulation of cardiac function in endotoxaemia. BRITISH JOURNAL OF PHARMACOLOGY. 133:U4-U4. Author weblink.
  • Cranshaw JH; Evans TW; Mitchell JA. (Apr 2001). Characterization of the effects of isoprostanes on platelet aggregation in human whole blood. Br J Pharmacol. 132:1699-1706. DOI.
  • Wort SJ; Mitchell JA; Evans TW. (Mar 2001). Inducible nitric oxide synthase: a tissue-specific affair?. Am J Physiol Lung Cell Mol Physiol. 280:L387-L389.
  • Lazzeri N; Belvisi MG; Patel HJ; Yacoub MH; Chung KF; Mitchell JA. (Jan 2001). Effects of prostaglandin E2 and cAMP elevating drugs on GM-CSF release by cultured human airway smooth muscle cells. Relevance to asthma therapy. Am J Respir Cell Mol Biol. 24:44-48.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Aug 2000). Reciprocal regulatory mechanisms exist between GM-CSF and COX-2 in human venous smooth muscle cells. EUROPEAN HEART JOURNAL. 21:161-161. Author weblink.
  • Price S; Mitchell JA; Anning PB; Etherington P; Evans TW. (1 Aug 2000). The myocardial dysfunction of endotoxaemia is exacerbated by nitric oxide synthase inhibition. EUROPEAN HEART JOURNAL. 21:486-486. Author weblink.
  • Jordan S; Mitchell JA; Quinlan GJ; Goldstraw P; Evans TW. (Apr 2000). The pathogenesis of lung injury following pulmonary resection. Eur Respir J. 15:790-799.
  • Stanford SJ; Pepper JR; Mitchell JA. (Mar 2000). Cyclooxygenase-2 regulates granulocyte-macrophage colony-stimulating factor, but not interleukin-8, production by human vascular cells: role of cAMP. Arterioscler Thromb Vasc Biol. 20:677-682.
  • Stanford SJ; Pepper JR; Mitchell JA. (Mar 2000). Release of GM-CSF and G-CSF by human arterial and venous smooth muscle cells: differential regulation by COX-2. Br J Pharmacol. 129:835-838. DOI.
  • Mitchell JA; Gray P; Anning PD; Woods M; Warner TD; Evans TW. (18 Feb 2000). Effects of nitric oxide-modulating amino acids on coronary vessels: relevance to sepsis. Eur J Pharmacol. 389:209-215.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Jan 2000). Conditioned medium from human stimulated venous smooth muscle cells inhibits neutrophil apoptosis: Relevance of endogenously produced GM-CSF and G-CSF. BRITISH JOURNAL OF PHARMACOLOGY. 129:U57-U57. Author weblink.
  • Woods M; Wood EG; Mitchell JA; Warner TD. (1 Jan 2000). Cytokine-stimulation of ET-1 release from human vascular smooth muscle cells (HVSMCs) is modulated by cAMP. BRITISH JOURNAL OF PHARMACOLOGY. 129:U12-U12. Author weblink.
  • Price S; Evans TW; Mitchell JA. (1 Jan 2000). Effect of endotoxaemia on the inotropic and chronotropic effects of endothelin: Role of cyclo-oxygenase. BRITISH JOURNAL OF PHARMACOLOGY. 129:U12-U12. Author weblink.
  • Breese EJ; Patchett SE; Warner TD; Mitchell JA. (1 Jan 2000). G-CSF production is elevated from antral biopsies of patients with gastritis, but only increased by indomethacin in patients negative for Helicobacter pylori infection. BRITISH JOURNAL OF PHARMACOLOGY. 129:U23-U23. Author weblink.
  • Woods M; Walcot NR; Wood EG; Mitchell JA; Warner TD. (1 Jan 2000). IL-4 and IL-13 modulate cytokine-induced endothelin-1 production in human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 129:U109-U109. Author weblink.
  • Brooks AVS; Mitchell JA; Burke-Gaffney A. (1 Jan 2000). Involvement of p38 mitogen-activated protein kinase in interleukin-8 release from human neutrophils. BRITISH JOURNAL OF PHARMACOLOGY. 129:U58-U58. Author weblink.
  • Gray PA; Warner TD; Vojnovic I; Parikh A; Scadding G; Del Soldato P; Mitchell JA. (1 Jan 2000). Leukotriene production in human blood is reduced by NO-aspirin but not aspirin: Comparisons between responses in healthy volunteers and aspirin-sensitive asthmatics. BRITISH JOURNAL OF PHARMACOLOGY. 129:U116-U116. Author weblink.
  • Gitlin JM; Evans TW; Pepper JR; Mitchell JA. (1 Jan 2000). The activators of soluble guanylyl cyclase inhibit PGE(2) release under conditions of high and low endogenous arachidonic acid. BRITISH JOURNAL OF PHARMACOLOGY. 129:U23-U23. Author weblink.
  • Price S; Evans TW; Mitchell JA. (1 Jan 2000). The effect of endotoxaemia on the inotropic response to isoprenaline: The role of cyclic AMP. BRITISH JOURNAL OF PHARMACOLOGY. 129:U11-U11. Author weblink.
  • Wort SJ; Mitchell JA; Woods M; Evans TW; Warner TD. (Nov 2000). The prostacyclin-mimetic cicaprost inhibits endogenous endothelin-1 release from human pulmonary artery smooth muscle cells. J Cardiovasc Pharmacol. 36:S410-S413.
  • Jordan S; Evans TW; Burke-Gaffney A; Mitchell JA. (1 Jan 2000). Toxins associated with gram negative and gram positive bacteria stimulate: IL-8 release from human blood: Implications for ARDS. BRITISH JOURNAL OF PHARMACOLOGY. 129:U58-U58. Author weblink.
  • Wort SJ; Evans TW; Woods M; Warner TD; Mitchell JA. (1 Dec 1999). Cicaprost, a stable prostacyclin analogue, inhibits endogenous endothelin-1 release in human pulmonary artery smooth muscle cells. THORAX. 54:A41-A41. Author weblink.
  • Wort SJ; Evans TW; Warner TD; Mitchell JA. (1 Dec 1999). Cyclooxygenase-2 induction represents an endogenous 'brake' on ET-1 production by human pulmonary artery smooth muscle. THORAX. 54:A41-A41. Author weblink.
  • Brooks AVS; Mitchell JA; Evans TW; Burke-Gaffney A. (1 Dec 1999). Stimulus-specific reduction of neutrophil interleukin-8 release in acute respiratory distress syndrome. THORAX. 54:A79-A79. Author weblink.
  • Woods M; Wood EG; Lees DM; Mitchell JA; Warner TD. (1 Nov 1999). A role for NF-kappa B in the stimulation by cytokines of endothelin-1 release in human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 128:U14-U14. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Nov 1999). COX-2 differentially regulates GM-CSF and G-CSF production by human venous smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 128:U14-U14. Author weblink.
  • Mitchell JA; Warner TD. (Nov 1999). Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy. Br J Pharmacol. 128:1121-1132. DOI.
  • Breese EJ; Wood EG; Gray PA; Curtis MJ; Warner TD; Mitchell JA. (1 Nov 1999). Effects of disease modifying anti-rheumatic drugs and corticosteroids on prostaglandin E-2, and GMCSF production by cytokine-stimulated human synoviocytes. BRITISH JOURNAL OF PHARMACOLOGY. 128:U17-U17. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Nov 1999). Endogenous GM-CSF modulates COX-2 activity in human venous smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 128:U28-U28. Author weblink.
  • Price S; Evans TW; Mitchell JA. (1 Nov 1999). Endotoxaemia alters inotropic response to isoprenaline in papillary muscles: An effect that is modulated by L-name. BRITISH JOURNAL OF PHARMACOLOGY. 128:U15-U15. Author weblink.
  • Arrigoni FI; Hislop AA; Haworth SG; Mitchell JA. (1 Nov 1999). Newborn intrapulmonary veins are more reactive than arteries in normal and hypertensive piglets. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 277:L887-L892. Author weblink.
  • Jordan S; Evans TW; Mitchell JA. (1 Nov 1999). Oxidative stress acts synergistically with IL-1 beta, but not TNF alpha, to enhance IL-8 release by human pulmonary artery smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 128:U17-U17. Author weblink.
  • Gray PA; Breese EJ; Wood EG; Del Soldato P; Warner TD; Mitchell JA. (1 Oct 1999). Comparison of NSAIDs and NO-NSAIDs on PGE(2) and GMCSF production by human synoviocytes. BRITISH JOURNAL OF PHARMACOLOGY. 128:U54-U54. Author weblink.
  • Patel HJ; Belvisi MG; Donnelly LE; Yacoub MH; Chung KF; Mitchell JA. (Oct 1999). Constitutive expressions of type I NOS in human airway smooth muscle cells: evidence for an antiproliferative role. FASEB J. 13:1810-1816.
  • Gitlin JM; Evans TW; Pepper JR; Mitchell JA. (1 Oct 1999). Regulation of cyclo-oxygenase activity by activators of soluble guanylyl cyclase in human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 128:U26-U26. Author weblink.
  • Breese EJ; Warner TD; Patchett SE; Mitchell JA. (1 Oct 1999). The prostacyclin analogue cicaprost reverses the increase in GM-CSF production caused by NSAID treatment of human gastric biopsies. BRITISH JOURNAL OF PHARMACOLOGY. 128:U15-U15. Author weblink.
  • McCartney SA; Mitchell JA; Fairclough PD; Farthing MJG; Warner TD. (1 Aug 1999). Selective COX-2 inhibitors and human inflammatory bowel disease. ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 13:1115-1117. Author weblink.
  • Jourdan KB; Evans TW; Lamb NJ; Goldstraw P; Mitchell JA. (Jul 1999). Autocrine function of inducible nitric oxide synthase and cyclooxygenase-2 in proliferation of human and rat pulmonary artery smooth-muscle cells: species variation. Am J Respir Cell Mol Biol. 21:105-110.
  • Warner TD; Giuliano F; Vojnovic I; Bukasa A; Mitchell JA; Vane JR. (22 Jun 1999). Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 96:7563-7568. Author weblink DOI.
  • Jourdan KB; Evans TW; Goldstraw P; Mitchell JA. (Jun 1999). Isoprostanes and PGE2 production in human isolated pulmonary artery smooth muscle cells: concomitant and differential release. FASEB J. 13:1025-1030.
  • Baines PB; Stanford S; Bishop-Bailey D; Sills JA; Thomson APJ; Mitchell JA; Fear SC; Hart CA; et alPetros AJ. (1 Jun 1999). Nitric oxide production in meningococcal disease is directly related to disease severity. CRITICAL CARE MEDICINE. 27:1187-1190. Author weblink DOI.
  • Woods M; Mitchell JA; Wood EG; Barker S; Walcot NR; Rees GM; Warner TD. (1 May 1999). Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: Evidence for intracellular endothelin-converting enzyme. MOLECULAR PHARMACOLOGY. 55:902-909. Author weblink.
  • Price S; Anning PB; Mitchell JA; Evans TW. (May 1999). Myocardial dysfunction in sepsis: mechanisms and therapeutic implications. Eur Heart J. 20:715-724.
  • McCartney SA; Mitchell JA; Warner TD; Farthing MJG. (1 Apr 1999). GM-CSF is produced in high concentrations by colonic mucosa from patients with ulcerative colitis and is down regulated by co-incubation with dexamethasone. GASTROENTEROLOGY. 116:A713-A713. Author weblink.
  • Price S; Evans TW; Mitchell JA. (1 Mar 1999). Atrial dysfunction induced by endotoxin in rats is modulated by L-arginine: Role of nitric oxide. BRITISH JOURNAL OF PHARMACOLOGY. 126:U44-U44. Author weblink.
  • Arrigoni FI; Hislop AA; Pollock J; Haworth SG; Mitchell JA. (1 Mar 1999). Changes in nitric oxide synthase activity in the porcine lung after birth. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A898-A898. Author weblink.
  • Arrigoni FI; Hislop AA; Mitchell JA; Haworth SG. (1 Mar 1999). Characterisation of venous responses in the developing porcine lung. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A899-A899. Author weblink.
  • Patel HJ; Belvisi MG; Donnelly LE; Yacoub MH; Chung KF; Mitchell JA. (1 Mar 1999). Constitutive expression of nNOS in human cultured airway smooth muscle cells: Evidence for an anti-proliferative role. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A531-A531. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Mar 1999). COX-2 inhibits GM-CSF release from human cultured arterial and venous smooth muscle cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A656-A656. Author weblink.
  • Woods M; Wood EG; Mitchell JA; Warner TD. (1 Mar 1999). Effect of tyrosine kinase inhibitors on cytokine-stimulated endothelin production in human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 126:U94-U94. Author weblink.
  • Breese EJ; Wood EG; Curtis MJ; Warner TD; Mitchell JA. (1 Mar 1999). Effects of COX-1 and COX-2-selective NSAIDs on prostaglandin E-2 and GM-CSF production by human synoviocytes. BRITISH JOURNAL OF PHARMACOLOGY. 126:U83-U83. Author weblink.
  • Price S; Mitchell JA; Anning PB; Evans TW. (1 Mar 1999). Effects of experimental sepsis on inotropic responses of isolated atria: The role of nitric oxide. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A245-A245. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Mar 1999). Evidence for a role of prostacyclin in COX-2 suppression of Gm-CSF release by human vascular cells. BRITISH JOURNAL OF PHARMACOLOGY. 126:U26-U26. Author weblink.
  • McCartney SA; Mitchell JA; Farthing MJG; Warner TD. (1 Mar 1999). GM-CSF is produced in high concentrations by inflamed colonic mucosa from patients with ulcerative colitis and is down-regulated by co-incubation with dexamethasone. BRITISH JOURNAL OF PHARMACOLOGY. 126:U78-U78. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Mar 1999). GM-CSF release from human cultured arterial and venous smooth muscle cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A656-A656. Author weblink.
  • Price S; Mitchell JA; Chen Y; Evans TW. (1 Mar 1999). High levels of nitric oxide synthase activity are expressed constitutively in atrial but not ventricular tissue: Modification by endotoxaemia. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A246-A246. Author weblink.
  • Patel HJ; Belvisi MG; Fadlon EJ; Rousell J; Haddad EB; Jose PJ; Mitchell JA; Chung KF. (1 Mar 1999). Induction of eotaxin expression and release from human airway smooth muscle cells by IL-1 beta & TNF alpha: Effects of IL-10 and corticosteroids. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A401-A401. Author weblink.
  • Lazzeri N; Mitchell JA; Patel HJ; Yacoub MH; Chung KF; Belvisi MG. (1 Mar 1999). Inhibitors of phosphodiesterase type 4 enzymes inhibit GMCSF release by cytokine treated human airway smooth muscle cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A395-A395. Author weblink.
  • Lazzeri N; Belvisi MG; Patel HJ; Yacoub MH; Chung KF; Mitchell JA. (1 Mar 1999). Inhibitors of phosphodiesterase type 4 enzymes inhibit RANTES release by cytokine treated human airway smooth muscle cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A401-A401.
  • Saunders MA; Belvisi MG; Cirino G; Barnes PJ; Warner TD; Mitchell JA. (Mar 1999). Mechanisms of prostaglandin E2 release by intact cells expressing cyclooxygenase-2: evidence for a 'two-component' model. J Pharmacol Exp Ther. 288:1101-1106.
  • Jordan SJ; Mitchell JA; Evans TW. (1 Mar 1999). Oxidant stress enhances interleukin-8 release by human pulmonary arteries. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A273-A273. Author weblink.
  • Woods M; Wood EG; Mitchell JA; Warner TD. (1 Mar 1999). Studies with CGS 26303, an inhibitor of endothelin converting enzyme, supports the presence of intracellular endothelin-converting enzyme in human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 126:U30-U30. Author weblink.
  • Jordan SJ; Jourdan KB; Evans TW; Mitchell JA. (1 Mar 1999). The importance of the smooth muscle component of pulmonary arteries in the generation of IL-8. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A511-A511. Author weblink.
  • Stanford SJ; Mitchell JA. (1 Mar 1999). The prolonged phase of ATP-induced vasodilatation in rat mesenteric vessels is mediated by a cannabinoid-type ligand. BRITISH JOURNAL OF PHARMACOLOGY. 126:U45-U45. Author weblink.
  • Hamilton LC; Mitchell JA; Tomlinson AM; Warner TD. (1 Feb 1999). Synergy between cyclo-oxygenase-2 induction and arachidonic acid supply in vivo: consequences for nonsteroidal antiinflammatory drug efficacy. FASEB JOURNAL. 13:245-251. Author weblink.
  • Bishop-Bailey D; Hla T; Mitchell JA. (1 Jan 1999). Cyclo-oxygenase-2 in vascular smooth muscle (Review). INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 3:41-48. Author weblink.
  • Stanford SJ; Pepper JR; Mitchell JA. (1 Dec 1998). GM-CSF release from human vascular smooth muscle cells is suppressed by co-induced COX-2. BRITISH JOURNAL OF PHARMACOLOGY. 125:U11-U11. Author weblink.
  • Belvisi MG; Saunders M; Yacoub M; Mitchell JA. (1 Nov 1998). Expression of cyclo-oxygenase-2 in human airway smooth muscle is associated with profound reductions in cell growth. BRITISH JOURNAL OF PHARMACOLOGY. 125:1102-1108. Author weblink DOI.
  • Mitchell JA; Evans TW. (Oct 1998). Cyclooxygenase-2 as a therapeutic target. Inflamm Res. 47 Suppl 2:S88-S92.
  • Bishop-Bailey D; Pepper JR; Larkin SW; Mitchell JA. (Oct 1998). Differential induction of cyclooxygenase-2 in human arterial and venous smooth muscle: role of endogenous prostanoids. Arterioscler Thromb Vasc Biol. 18:1655-1661.
  • Bishop-Bailey D; Burke-Gaffney A; Hellewell PG; Pepper JR; Mitchell JA. (10 Aug 1998). Cyclo-oxygenase-2 regulates inducible ICAM-1 and VCAM-1 expression in human vascular smooth muscle cells. Biochem Biophys Res Commun. 249:44-47. DOI.
  • Mitchell JA; Belvisi MG. (1 Aug 1998). Cyclo-oxygenase - Reply. THORAX. 53:719-720. Author weblink.
  • Chester AH; Borland JA; Buttery LD; Mitchell JA; Cunningham DA; Hafizi S; Hoare GS; Springall DR; et alPolak JM; Yacoub MH. (Jun 1998). Induction of nitric oxide synthase in human vascular smooth muscle: interactions between proinflammatory cytokines. Cardiovasc Res. 38:814-821.
  • Bryant CE; Appleton I; Mitchell JA. (8 May 1998). Vascular endothelial growth factor upregulates constitutive cyclooxygenase 1 in primary bovine and human endothelial cells. LIFE SCIENCES. 62:2195-2201. Author weblink DOI.
  • Jourdan KB; Evans TW; Mitchell JA. (1 Mar 1998). Interleukin-1 beta inhibits proliferation of human pulmonary artery smooth muscle cells via a cyclooxygenase-2 dependent pathway. BRITISH JOURNAL OF PHARMACOLOGY. 123:U42-U42. Author weblink.
  • Jourdan KB; Mitchell JA; Evans TW. (1 Mar 1998). Interleukin-1 beta inhibits proliferation of rat pulmonary artery smooth muscle cells through a nitric oxide-dependent pathway. BRITISH JOURNAL OF PHARMACOLOGY. 123:U42-U42. Author weblink.
  • Jordan KB; Evans TW; Mitchell JA. (1 Mar 1998). Production of the isoprostane, 8-iso PGF(2)alpha by human pulmonary artery smooth muscle cells is cyclooxygenase-2-dependent. BRITISH JOURNAL OF PHARMACOLOGY. 123:U100-U100. Author weblink.
  • Chabot F; Mitchell JA; Gutteridge JMC; Evans TW. (1 Mar 1998). Reactive oxygen species in acute lung injury. EUROPEAN RESPIRATORY JOURNAL. 11:745-757. Author weblink.
  • Cirino G; Saunders M; Belvisi MG; Jourdan KB; Evans TW; Coppini A; Mitchell JA. (1 Mar 1998). Relative potencies of nonsteroidal anti-inflammatory drugs on purified cyclo-oxygenase-1 and -2. BRITISH JOURNAL OF PHARMACOLOGY. 123:U101-U101. Author weblink.
  • Mitchell JA; Bishop-Bailey D; Evans TW; Giembycz MA; Belvisi MG; Chivers S; Williams TJ; Pepper JR. (1 Mar 1998). Release of neutrophil activating cytokines by human arterial and venous smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 123:U56-U56. Author weblink.
  • Hamilton LC; Tomlinson A; Dye LJ; Mitchell JA; Warner TD. (1 Mar 1998). Use of selective enzyme inhibitors provide NO evidence for cross-talk between inducible nitric oxide synthase and cyclooxygenase-2 in endotoxin-treated rats. BRITISH JOURNAL OF PHARMACOLOGY. 123:U25-U25. Author weblink.
  • Niebauer J; Webb-Peploe KM; Jourdan K; Mitchell JA; Quinlan GJ; Coats AJS. (1 Feb 1998). Chronic exercise training modulates oxidative stress in patients with chronic heart failure. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 31:509A-509A. Author weblink DOI.
  • Patel HJ; Mitchell JA; Chung FK; Belvisi MG. (1 Jan 1998). Endogenous nitric oxide suppresses growth of human ASM cells. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 358:R310-R310. Author weblink.
  • John M; Au BT; Jose PJ; Lim S; Saunders M; Barnes PJ; Mitchell JA; Belvisi MG; et alChung KF. (Jan 1998). Expression and release of interleukin-8 by human airway smooth muscle cells: inhibition by Th-2 cytokines and corticosteroids. Am J Respir Cell Mol Biol. 18:84-90.
  • Lu YT; Liu SF; Mitchell JA; Malik AB; Hellewell PG; Evans TW. (Jan 1998). The role of endogenous nitric oxide in modulating ischemia-reperfusion injury in the isolated, blood-perfused rat lung. Am J Respir Crit Care Med. 157:273-279.
  • Mitchell JA; Belvisi MG. (1 Nov 1997). Too many COX (cyclo-oxygenase) spoil the broth: aspirin-sensitive asthma and 5-lipoxygenase. THORAX. 52:933-935. Author weblink.
  • Woods M; BishopBailey D; Pepper JR; Evans TW; Mitchell JA; Warner TD. (1 Oct 1997). Cytokine and LPS stimulation of endothelin-1 release from internal mammary artery and saphenous vein smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 122:P18-P18. Author weblink.
  • BishopBailey D; Pepper JR; Larkin S; Evans T; Mitchell JA. (1 Oct 1997). Differential induction of cyclo-oxygenase-2 in human arterial and venous smooth muscle cells: Role of endogenous prostanoids. BRITISH JOURNAL OF PHARMACOLOGY. 122:P19-P19. Author weblink.
  • Hamilton LC; Mitchell JA; Warner TD. (1 Oct 1997). Induction of COX-2 in vivo leads to greatly increased production of 6-keto-PGF(1 alpha) following administration of exogenous arachidonic acid or bradykinin. BRITISH JOURNAL OF PHARMACOLOGY. 122:P22-P22. Author weblink.
  • BishopBailey D; BurkeGaffney A; Hellewell PG; Pepper JR; Mitchell JA. (1 Oct 1997). Interleukin (IL)-1 beta-induced cyclo-oxygenase-2 activity inhibits IL-1 beta-induced expression of ICAM-1-and IL-4-induced expression of VCAM-1 on saphenous vein smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 122:P21-P21. Author weblink.
  • BishopBailey D; Pepper JR; Larkin S; Evans T; Mitchell JA. (1 Oct 1997). Interleukin-1 beta induces anti-proliferative prostanoids via cyclo-oxygenase-2 in human saphenous vein and internal mammary artery smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 122:P20-P20. Author weblink.
  • Bishop-Bailey D; Pepper JR; Haddad EB; Newton R; Larkin SW; Mitchell JA. (Sep 1997). Induction of cyclooxygenase-2 in human saphenous vein and internal mammary artery. Arterioscler Thromb Vasc Biol. 17:1644-1648.
  • Griffiths MJ; Curzen NP; Mitchell JA; Evans TW. (Aug 1997). In vivo treatment with endotoxin increases rat pulmonary vascular contractility despite NOS induction. Am J Respir Crit Care Med. 156:654-658.
  • Mitchell JA; Williams FM; Williams TJ; Larkin SW. (Aug 1997). Role of nitric oxide in the dilator actions of capsaicin-sensitive nerves in the rabbit coronary circulation. Neuropeptides. 31:333-338.
  • Chabot F; Mitchell JA; Quinlan GJ; Evans TW. (Jun 1997). Characterization of the vasodilator properties of peroxynitrite on rat pulmonary artery: role of poly (adenosine 5'-diphosphoribose) synthase. Br J Pharmacol. 121:485-490. DOI.
  • Mitchell JA; Saunders M; Barnes PJ; Newton R; Belvisi MG. (Jun 1997). Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 51:907-912.
  • Bishop-Bailey D; Larkin SW; Warner TD; Chen G; Mitchell JA. (May 1997). Characterization of the induction of nitric oxide synthase and cyclo-oxygenase in rat aorta in organ culture. Br J Pharmacol. 121:125-133. DOI.
  • Jourdan KB; Mitchell JA; Evans TW. (28 Apr 1997). Release of isoprostanes by human pulmonary artery in organ culture: a cyclo-oxygenase and nitric oxide dependent pathway. Biochem Biophys Res Commun. 233:668-672. DOI.
  • Jourdan KB; Evans TW; Curzen NP; Mitchell JA. (Apr 1997). Evidence for a dilator function of 8-iso prostaglandin F2 alpha in rat pulmonary artery. Br J Pharmacol. 120:1280-1285. DOI.
  • BishopBailey D; Pepper JR; Larkin S; Evans TW; Mitchell JA. (1 Mar 1997). Cyclo-oxygenase-2 accounts for the sustained release of prostaglandin E(2) from cytokine stimulated human vascular smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 120:P73-P73. Author weblink.
  • Bernareggi M; Mitchell JA; Barnes PJ; Belvisi MG. (Mar 1997). Dual action of nitric oxide on airway plasma leakage. Am J Respir Crit Care Med. 155:869-874.
  • Belvisi MG; Saunders MA; Haddad el-B; Hirst SJ; Yacoub MH; Barnes PJ; Mitchell JA. (Mar 1997). Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type. Br J Pharmacol. 120:910-916. DOI.
  • BishopBailey D; Haddad EB; Larkin S; Newton R; Pepper JR; Evans TW; Mitchell JA. (1 Mar 1997). Induction of cyclo-oxygenase-2 in human internal mammary artery and saphenous vein in organ culture. BRITISH JOURNAL OF PHARMACOLOGY. 120:P72-P72. Author weblink.
  • Jourdan KB; Curzen NP; Evans TW; Mitchell JA. (1 Mar 1997). The isoprostane 8-iso prostaglandin F-2 alpha vasodilates rat pulmonary artery via the release of nitric oxide. BRITISH JOURNAL OF PHARMACOLOGY. 120:P166-P166. Author weblink.
  • Saunders MA; Mitchell JA; Seldon PM; Yacoub MH; Barnes PJ; Giembycz MA; Belvisi MG. (Feb 1997). Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: suppression by dexamethasone. Br J Pharmacol. 120:545-546. DOI.
  • Curzen NP; Mitchell JA; Jourdan KB; Griffiths MJ; Evans TW. (Dec 1996). Endothelin-1-induced contraction of pulmonary arteries from endotoxemic rats is attenuated by the endothelin-A receptor antagonist, BQ123. Crit Care Med. 24:2007-2013.
  • Saunders MA; Belvisi MG; Corden MB; Fox AJ; Evans TW; Barnes PJ; Mitchell JA. (1 Oct 1996). Exacerbation of the release of prostaglandin E(2) by bradykinin after COX-2 induction in human airway epithelial cells. BRITISH JOURNAL OF PHARMACOLOGY. 119:P46-P46. Author weblink.
  • BishopBailey D; Larkin SW; Williams TJ; Mitchell JA. (1 Oct 1996). Roles of nitric oxide and COX-metabolites in proliferation of rat aortic segments in organ culture. BRITISH JOURNAL OF PHARMACOLOGY. 119:P77-P77. Author weblink.
  • Jourdan KB; Curzen NP; Evans TW; Mitchell JA. (1 Jul 1996). Nitric oxide compromises the constrictor effects of the non-cyclooxygenase-derived prostanoid, 8-iso prostaglandin F-2 alpha. BRITISH JOURNAL OF PHARMACOLOGY. 118:P85-P85.
  • Stanford SJ; Mitchell JA; BishopBailey D; Williams TJ; Williams FM; Petros AJ; Larkin SW. (1 Jul 1996). The dilator response to sensory nerve stimulation in the mesenteric circulation of the rat is modulated prejunctionally by nitric oxide. BRITISH JOURNAL OF PHARMACOLOGY. 118:P83-P83. Author weblink.
  • Curzen NP; Jourdan KB; Mitchell JA. (Jun 1996). Endothelial modification of pulmonary vascular tone. Intensive Care Med. 22:596-607.
  • BishopBailey D; Larkin SW; Pepper JR; Yacoub M; Williams TJ; Mitchell JA. (1 Apr 1996). Comparison of the ability of human, rat and rabbit vessels to produce nitric oxide and prostanoids in response to LPS. BRITISH JOURNAL OF PHARMACOLOGY. 117:P78-P78. Author weblink.
  • Mitchell JA; Larkin S; Williams TJ. (9 Nov 1995). Cyclooxygenase-2: regulation and relevance in inflammation. Biochem Pharmacol. 50:1535-1542.
  • Belvisi M; Barnes PJ; Larkin S; Yacoub M; Tadjkarimi S; Williams TJ; Mitchell JA. (5 Sep 1995). Nitric oxide synthase activity is elevated in inflammatory lung disease in humans. Eur J Pharmacol. 283:255-258.
  • BISHOPBAILEY D; LARKIN SW; GRIFFITHS MJD; SWAINE J; PEPPER J; WILLIAMS TJ; MITCHELL JA. (1 Jul 1995). CHARACTERIZATION OF PROSTACYCLIN (PGI(2)) AND PROSTAGLANDIN E(2) (PGE(2)) RELEASE FROM HUMAN SAPHENOUS-VEIN IN RESPONSE TO BACTERIAL LPS. BRITISH JOURNAL OF PHARMACOLOGY. 115:P136-P136. Author weblink.
  • Belvisi MG; Ward JK; Mitchell JA; Barnes PJ. (Jan 1995). Nitric oxide as a neurotransmitter in human airways. Arch Int Pharmacodyn Ther. 329:97-110.
  • Mitchell JA; Belvisi MG; Akarasereenont P; Robbins RA; Kwon OJ; Croxtall J; Barnes PJ; Vane JR. (Nov 1994). Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone. Br J Pharmacol. 113:1008-1014.
  • MITCHELL JA; BATCHELOR J; CHAPEL H; SPIERS CN; SIM E. (1 May 1987). ERYTHROCYTE COMPLEMENT RECEPTOR TYPE-1 (CR-1) EXPRESSION AND CIRCULATING IMMUNE-COMPLEX (CIC) LEVELS IN HYDRALAZINE-INDUCED SLE. CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 68:446-456. Author weblink.
  • Kimber I; Pierce BB; Mitchell JA; Kinnaird A. (1987). Depression of lymph node cell proliferation induced by oxazolone. Int Arch Allergy Appl Immunol. 84:256-262.

Conferences

  • Kirkby NS; Harrington LS; Lundberg MH; Hoefer T; Warner TD; Mitchell JA. CONTRIBUTION OF COX1 AND COX2 TO PROSTACYCLIN RELEASE BY HEALTHY MOUSE TISSUES. 10th World Congress on Inflammation, 25 Jun 2011 - 29 Jun 2011. 60:116-117. BIRKHAUSER VERLAG AG (1 Jun 2011). Author weblink.
  • Reed DM; Foldes G; Gatheral T; Badiger RV; Wheeler-Jones CP; Ali NN; Harding SE; Mitchell JA. ENDOTHELIN-1 RELEASE FROM HUMAN EMBRYONIC STEM CELL DERIVED-ENDOTHELIAL CELLS (HESC-EC): COMPARISONS WITH HUMAN ENDOTHELIAL CELLS. 10th World Congress on Inflammation, 25 Jun 2011 - 29 Jun 2011. 60:224-224. BIRKHAUSER VERLAG AG (1 Jun 2011). Author weblink.
  • Wright WR; Kirkby NS; Harrington LS; Lundberg MH; Paul-Clark MJ; Warner TD; Mitchell JA. ROLE OF COX-1 AND COX-2 IN THE RELEASE OF PROSTANOIDS IN MURINE LUNG AND ISOLATED LUNG FIBROBLASTS. 10th World Congress on Inflammation, 25 Jun 2011 - 29 Jun 2011. 60:232-232. BIRKHAUSER VERLAG AG (1 Jun 2011). Author weblink.
  • Mitchell JA; Badiger R; Tietz A; Atkin C; Gashaw H; Hinton HJ; Hansel TT; Singer T; et alManigold T. INTERFERON (IFN) ALPHA PREPARATIONS ACTIVATE HUMAN LUNG MICROVASCULAR ENDOTHELIAL CELLS TO RELEASE THE CHEMOKINE IP10. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, 29 Oct 2010 - 2 Nov 2010. 52:809A-810A. WILEY-BLACKWELL (1 Oct 2010). Author weblink.
  • Usmani OS; Watson EM; Meah SN; Hodson ME; Mitchell JA. DECLINING RESPIRATORY CLINICAL ACADEMICS: A MODEL FOR REVERSING THE TREND?. Winter Meeting of the British-Thoracic-Society, 2 Dec 2009 - 4 Dec 2009. 64:A165-A166. B M J PUBLISHING GROUP (1 Dec 2009). DOI.
  • Armstrong PCJ; Dhanji AA; Tucker AT; Mitchell JA; Warner TD. URINARY 11-DEHYDRO-THROMBOXANE B2 AS A MARKER OF THE ANTI-PLATELET EFFECTS OF CLOPIDOGREL OR ASPIRIN THERAPY IN HEALTHY MALE VOLUNTEERS. Spring Meeting of the British-Society-for-Cardiovascular-Research, 2 Apr 2009 - 4 Apr 2009. 95. B M J PUBLISHING GROUP (15 Nov 2009). Author weblink DOI.
  • Mitchell JA. Oxidative stress by environmental and host derived sources leading to lung inflammation. 46th Congress of the European-Societies-of-Toxicology, 13 Sep 2009 - 16 Sep 2009. 189:S44-S44. ELSEVIER IRELAND LTD (13 Sep 2009). Author weblink DOI.
  • Mitchell JA; Ali F; Bailey L; Moreno L; Harrington LS. Role of nitric oxide and prostacyclin as vasoactive hormones released by the endothelium. Life Science Conference 2007. 93:141-147. (1 Jan 2008).
  • Moreno L; Faro R; Hislop A; Sturton G; Perez-Vizcaino F; Mitchell JA. Endothelium-dependent dilatation of mice pulmonary arteries increases with postnatal maturation. Experimental Biology 2007 Annual Meeting. 21:A1164-A1164. (Apr 2007).
  • Patel TA; Mitchell JA; Warner TD; Harding SE. Gram positive bacteria reduce viability and contraction of isolated cardiomyocytes: Role of endothelin-1. 28th Annual International-Society-for-Heart-Research North American Section Meeting. 40:1007-1007. (Jun 2006).
  • Cartwright N; Quesniaux V; Ryffel B; Evans TW; Mitchell JA. Gram positive bacteria signal exclusively through toll like receptors 2 and 6 in blood vessels. 78th Annual Scientific Session of the American-Heart-Association, 13 Nov 2005 - 16 Nov 2005. 112:U292-U292. LIPPINCOTT WILLIAMS & WILKINS (25 Oct 2005). Author weblink.
  • Harrington LS; Carrier MJ; Mitchell JA. Toll like receptor 4 is essential for a functional endothelium in mesenteric arteries. 78th Annual Scientific Session of the American-Heart-Association. 112:U366-U367. (25 Oct 2005).
  • Harrington LS; Mitchell JA. Activation of P2X-like receptors in rat isolated 2(nd) order mesenteric arteries induces vasodilation: Role of EDHF. Meeting of the British-Pharmacological-Society. 140:U9-U9. (Sep 2003).
  • Fleet MR; Anandarajah J; Walters MJ; Belcher PE; Sriskandan S; Mitchell JA. Cigarette smoke inhibits the induction of NOSII activity in murine macrophages stimulated with Gram negative bacteria. Meeting of the British-Pharmacological-Society. 140:U7-U7. (Sep 2003).
  • Somuyiwa A; Stanford S; Gitlin J; Vojnovic I; Warner TD; Hislop A; Howarth S; Mitchell JA. Cyclo-oxygenase-2 expression in the lung in the period of pulmonary development after birth. Meeting of the British-Pharmacological-Society. 140:U12-U12. (Sep 2003).
  • Anandarajah J; Fleet MR; Walters MJ; Belcher PE; Sriskandan S; Mitchell JA. Gram positive and Gram negative bacteria synergise to cause nitric oxide synthase induction in murine macrophages. Meeting of the British-Pharmacological-Society. 140:U8-U8. (Sep 2003).
  • Stanford SJ; San H; Nabel EG; Hislop AA; Haworth SG; Mitchell JA. Induction of heme oxygenase-1 in the murine lung afterbirth does not influence vascular remodelling. Meeting of the British-Pharmacological-Society. 140:U11-U11. (Sep 2003).
  • Jimenez R; Warner TD; Belcher PE; Vojnovic I; Mitchell JA. Induction of NOSII and COX activity in primary cultures of murine smooth muscle cells. Meeting of the British-Pharmacological-Society. 140:U9-U9. (Sep 2003).
  • Walters MJ; Mitchell JA. Cigarette smoke extract (CSE) stimulates human THP-1 monocytes directly and synergises with IL-1 beta to release IL-8. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section. 138:U22-U22. (Apr 2003).
  • Belcher E; Evans TW; Sriskandan S; Mitchell JA. Escherichia coli induces nitric oxide release in cardiovascular tissue via a toll like receptor 4-independent pathway. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section. 138:U16-U16. (Apr 2003).
  • Belcher E; Evans TW; Sriskandan S; Mitchell JA. Gram-positive Staphylococcus aureus contrasts with Gram-negative Escherichia coli in the induction of tumour necrosis factor-alpha and nitric oxide from macrophages in urine. Meeting of the Intensive-Care-Society. 90:540P-541P. (Apr 2003).
  • Stanford SJ; Walters MJ; Hislop AA; Haworth SG; Evans TW; Mitchell JA. Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, 7 Jan 2003 - 10 Jan 2003. 138:U26-U26. NATURE PUBLISHING GROUP (1 Apr 2003). Author weblink.
  • Stanford SJ; San H; Nabel EG; Hislop AA; Haworth SG; Mitchell JA. Heme oxygenase-1 deficient mice do not appear to have pulmonary hypertension. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section. 138:U25-U25. (Apr 2003).
  • Stanford SJ; Hislop AA; Haworth SG; Mitchell JA. Induction of heme oxygenase-1 in the porcine lung after birth. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section. 138:U25-U25. (Apr 2003).
  • Belcher E; Evans TW; Sriskandan S; Mitchell JA. Staphylococcus aureus induces nitric oxide release in cardiovascular tissue via a toll like receptor 2-independent pathway. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, 7 Jan 2003 - 10 Jan 2003. 138:U16-U16. NATURE PUBLISHING GROUP (1 Apr 2003). Author weblink.
  • Walters MJ; Warner TD; Bishop-Bailey D; Mitchell JA. The PPAR gamma ligand 15-deoxy-Delta(12,14)-prostaglandin J(2) (15D-PGJ(2)) inhibits proliferation and cytokine release from human pulmonary artery smooth muscle. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section. 138:U66-U66. (Apr 2003).
  • Belcher E; Evans TW; Sriskandan S; Mitchell JA. The main site of iNOS activity induced by Gram postive Staphylococcus aureus may be blood vessels and not macrophages: Comparisons with Gram negative Escherichia coli. Winter Meeting of the British-Thoracic-Society. 57:U28-U28. (Dec 2002).
  • Woods M; Wood EG; Mitchell JA; Warner TD. Cyclic AMP regulates cytokine stimulation of endothelin-1 release in human vascular smooth muscle cells. 6th International Symposium on Endothelin, 10 Oct 1999 - 14 Oct 1999. 36:S404-S406. LIPPINCOTT WILLIAMS & WILKINS (1 Jan 2000). Author weblink DOI.
  • Woods M; Wood EG; Mitchell JA; Warner TD. Signal transduction pathways involved in cytokine stimulation of endothelin-1 release from human vascular smooth muscle cells. 6th International Symposium on Endothelin, 10 Oct 1999 - 14 Oct 1999. 36:S407-S409. LIPPINCOTT WILLIAMS & WILKINS (1 Jan 2000). Author weblink DOI.
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