Publications

Journals

• Chambers JC; Zhang W; Lord GM; van der Harst P; Lawlor DA; Sehmi JS; Gale DP; Wass MN; et alAhmadi KR; Bakker SJ; Beckmann J; Bilo HJ; Bochud M; Brown MJ; Caulfield MJ; Connell JM; Cook HT; Cotlarciuc I; Davey Smith G; de Silva R; Deng G; Devuyst O; Dikkeschei LD; Dimkovic N; Dockrell M; Dominiczak A; Ebrahim S; Eggermann T; Farrall M; Ferrucci L; Floege J; Forouhi NG; Gansevoort RT; Han X; Hedblad B; Homan van der Heide JJ; Hepkema BG; Hernandez-Fuentes M; Hypponen E; Johnson T; de Jong PE; Kleefstra N; Lagou V; Lapsley M; Li Y; Loos RJ; Luan J; Luttropp K; Maréchal C; Melander O; Munroe PB; Nordfors L; Parsa A; Peltonen L; Penninx BW; Perucha E; Pouta A; Prokopenko I; Roderick PJ; Ruokonen A; Samani NJ; Sanna S; Schalling M; Schlessinger D; Schlieper G; Seelen MA; Shuldiner AR; Sjögren M; Smit JH; Snieder H; Soranzo N; Spector TD; Stenvinkel P; Sternberg MJ; Swaminathan R; Tanaka T; Ubink-Veltmaat LJ; Uda M; Vollenweider P; Wallace C; Waterworth D; Zerres K; Waeber G; Wareham NJ; Maxwell PH; McCarthy MI; Jarvelin MR; Mooser V; Abecasis GR; Lightstone L; Scott J; Navis G; Elliott P; Kooner JS. (May 2010). Genetic loci influencing kidney function and chronic kidney disease. Nat Genet. 42:373-375. DOI.
• Chambers JC; Zhao J; Terracciano CM; Bezzina CR; Zhang W; Kaba R; Navaratnarajah M; Lotlikar A; et alSehmi JS; Kooner MK; Deng G; Siedlecka U; Parasramka S; El-Hamamsy I; Wass MN; Dekker LR; de Jong JS; Sternberg MJ; McKenna W; Severs NJ; de Silva R; Wilde AA; Anand P; Yacoub M; Scott J; Elliott P; Wood JN; Kooner JS. (Feb 2010). Genetic variation in SCN10A influences cardiac conduction. Nat Genet. 42:149-152. DOI.
• Chambers JC; Zhang W; Zabaneh D; Sehmi J; Jain P; McCarthy MI; Froguel P; Ruokonen A; et alBalding D; Jarvelin MR; Scott J; Elliott P; Kooner JS. (Nov 2009). Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians. Diabetes. 58:2703-2708. DOI.
• Chambers JC; Zhang WH; Li Y; Sehmi J; Wass MN; Zabaneh D; Hoggart C; Bayele H; et alMcCarthy MI; Peltonen L; Freimer NB; Srai SK; Maxwell PH; Sternberg MJE; Ruokonen A; Abecasis G; Jarvelin MR; Scott J; Elliott P; Kooner JS. (Nov 2009). Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. NAT GENET. 41:1170-1172. DOI.
• Zabaneh D; Chambers JC; Elliott P; Scott J; Balding DJ; Kooner JS. (Dec 2009). Heritability and genetic correlations of insulin resistance and component phenotypes in Asian Indian families using a multivariate analysis. Diabetologia. 52:2585-2589. DOI.
• Elliott P; Chambers JC; Zhang WH; Clarke R; Hopewell JC; Peden JF; Erdmann J; Braund P; et alEngert JC; Bennett D; Coin L; Ashby D; Tzoulaki I; Brown IJ; Mt-Isa S; McCarthy MI; Peltonen L; Freimer NB; Farrall M; Ruokonen A; Hamsten A; Lim N; Froguel P; Waterworth DM; Vollenweider P; Waeber G; Jarvelin MR; Mooser V; Scott J; Hall AS; Schunkert H; Anand SS; Collins R; Samani NJ; Watkins H; Kooner JS. (1 Jul 2009). Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease. JAMA-J AM MED ASSOC. 302:37-48.
• Yuan X; Waterworth D; Perry JR; Lim N; Song K; Chambers JC; Zhang W; Vollenweider P; et alStirnadel H; Johnson T; Bergmann S; Beckmann ND; Li Y; Ferrucci L; Melzer D; Hernandez D; Singleton A; Scott J; Elliott P; Waeber G; Cardon L; Frayling TM; Kooner JS; Mooser V. (Oct 2008). Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet. 83:520-528. DOI.
• Chambers JC; Elliott P; Zabaneh D; Zhang WH; Li Y; Froguel P; Balding D; Scott J; et alKooner JS. (Jun 2008). Common genetic variation near MC4R is associated with waist circumference and insulin resistance. NAT GENET. 40:716-718. DOI.
• Kooner JS; Chambers JC; Aguilar-Salinas CA; Hinds DA; Hyde CL; Warnes GR; Perez FJG; Frazer KA; et alElliott P; Scott J; Milos PM; Cox DR; Thompson JF. (Feb 2008). Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. NAT GENET. 40:149-151. DOI.
• Fearnside JF; Dumas ME; Rothwell AR; Wilder SP; Cloarec O; Toye A; Blancher C; Holmes E; et alTatoud R; Barton RH; Scott J; Nicholson JK; Gauguier D. (2008). Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PLoS One. 3:e1668. DOI.
• Scott J. (22 Nov 2007). The liver X receptor and atherosclerosis. N Engl J Med. 357:2195-2197. DOI.
• Toye AA; Dumas ME; Blancher C; Rothwell AR; Fearnside JF; Wilder SP; Bihoreau MT; Cloarec O; et alAzzouzi I; Young S; Barton RH; Holmes E; McCarthy MI; Tatoud R; Nicholson JK; Scott J; Gauguier D. (Sep 2007). Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice. DIABETOLOGIA. 50:1867-1879. DOI.
• Seth A; Steel JH; Nichol D; Pocock V; Kumaran MK; Fritah A; Mobberley M; Ryder TA; et alRowlerson A; Scott J; Poutanen M; White R; Parker M. (Sep 2007). The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle. CELL METAB. 6:236-245. DOI.
• Parry S; Ledger V; Tissot B; Haslam SM; Scott J; Morris HR; Dell A. (Jun 2007). Integrated mass spectrometric strategy for characterizing the glycans from glycosphingolipids and glycoproteins: direct identification of sialyl Le(x) in mice. GLYCOBIOLOGY. 17:646-654. DOI.
• Dumas ME; Wilder SP; Bihoreau MT; Barton RH; Fearnside JF; Argoud K; D'Amato L; Wallis RH; et alBlancher C; Keun HC; Baunsgaard D; Scott J; Sidelmann UG; Nicholson JK; Gauguier D. (May 2007). Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models. Nat Genet. 39:666-672. DOI.
• Griffin JL; Scott J; Nicholson JK. (Jan 2007). The influence of pharmacogenetics on fatty liver disease in the wistar and kyoto rats: a combined transcriptomic and metabonomic study. J Proteome Res. 6:54-61. DOI.
• Dumas ME; Barton RH; Toye A; Cloarec O; Blancher C; Rothwell A; Fearnside J; Tatoud R; et alBlanc V; Lindon JC; Mitchell SC; Holmes E; McCarthy MI; Scott J; Gauguier D; Nicholson JK. (15 Aug 2006). Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc Natl Acad Sci U S A. 103:12511-12516. DOI.
• Parry S; Hadaschik D; Blancher C; Kumaran MK; Bochkina N; Morris HR; Richardson S; Aitman TJ; et alGauguier D; Siddle K; Scott J; Dell A. (Apr 2006). Glycomics investigation into insulin action. Biochim Biophys Acta. 1760:652-668. DOI.
• Scott J. (Jun 2004). Pathophysiology and biochemistry of cardiovascular disease. Curr Opin Genet Dev. 14:271-279. DOI.
• Griffin JL; Bonney SA; Mann C; Hebbachi AM; Gibbons GF; Nicholson JK; Shoulders CC; Scott J. (13 Apr 2004). An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver. Physiol Genomics. 17:140-149. DOI.
• Eichenbaum-Voline S; Olivier M; Jones EL; Naoumova RP; Jones B; Gau B; Patel HN; Seed M; et alBetteridge DJ; Galton DJ; Rubin EM; Scott J; Shoulders CC; Pennacchio LA. (Jan 2004). Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 24:167-174. DOI.
• Naoumova RP; Bonney SA; Eichenbaum-Voline S; Patel HN; Jones B; Jones EL; Amey J; Colilla S; et alNeuwirth CK; Allotey R; Seed M; Betteridge DJ; Galton DJ; Cox NJ; Bell GI; Scott J; Shoulders CC. (1 Nov 2003). Confirmed locus on chromosome 11p and candidate loci on 6q and 8p for the triglyceride and cholesterol traits of combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 23:2070-2077. DOI.
• Chester A; Somasekaram A; Tzimina M; Jarmuz A; Gisbourne J; O'Keefe R; Scott J; Navaratnam N. (1 Aug 2003). The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay. EMBO J. 22:3971-3982. DOI.
• Jones B; Jones EL; Bonney SA; Patel HN; Mensenkamp AR; Eichenbaum-Voline S; Rudling M; Myrdal U; et alAnnesi G; Naik S; Meadows N; Quattrone A; Islam SA; Naoumova RP; Angelin B; Infante R; Levy E; Roy CC; Freemont PS; Scott J; Shoulders CC. (May 2003). Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders. Nat Genet. 34:29-31. DOI.
• Scott J. (Apr 2003). ATVB in focus - Lipoproteins, inflammation, and atherosclerosis. ARTERIOSCL THROM VAS. 23:528-528. DOI.
• Wallace CA; Ali S; Glazier AM; Norsworthy PJ; Carlos DC; Scott J; Freeman TC; Stanton LW; et alKwitek AE; Aitman TJ. (Apr 2002). Radiation hybrid mapping of 70 rat genes from a data set of differentially expressed genes. Mamm Genome. 13:194-197. DOI.
• Jarmuz A; Chester A; Bayliss J; Gisbourne J; Dunham I; Scott J; Navaratnam N. (Mar 2002). An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics. 79:285-296. DOI.
• Glazier AM; Scott J; Aitman TJ. (Feb 2002). Molecular basis of the Cd36 chromosomal deletion underlying SHR defects in insulin action and fatty acid metabolism. Mamm Genome. 13:108-113. DOI.
• Scott J. (2002). The pathogenesis of atherosclerosis and new opportunities for treatment and prevention. J Neural Transm Suppl. 1-17.
• Griffin JL; Mann CJ; Scott J; Shoulders CC; Nicholson JK. (7 Dec 2001). Choline containing metabolites during cell transfection: an insight into magnetic resonance spectroscopy detectable changes. FEBS Lett. 509:263-266.
• Blanc V; Navaratnam N; Henderson JO; Anant S; Kennedy S; Jarmuz A; Scott J; Davidson NO. (30 Mar 2001). (O)over-cap vertical bar identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing. J BIOL CHEM. 276:10272-10283.
• Chester A; Scott J; Anant S; Navaratnam N. (15 Nov 2000). RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA. Biochim Biophys Acta. 1494:1-13.
• Read J; Anderson TA; Ritchie PJ; Vanloo B; Amey J; Levitt D; Rosseneu M; Scott J; et alShoulders CC. (29 Sep 2000). A mechanism of membrane neutral lipid acquisition by the microsomal triglyceride transfer protein. J Biol Chem. 275:30372-30377. DOI.
• Neuberger MS; Scott J. (8 Sep 2000). Immunology - RNA editing AIDs antibody diversification?. SCIENCE. 289:1705-1706.
• Scott J. (Sep 2000). Pulling apart pulmonary hypertension. NAT GENET. 26:3-4.
• Scott J; Shoulders C; Navaratnam N; Aitman T. (Aug 2000). The genetics of the metabolic overlap syndrome. Proc Nutr Soc. 59:439.
• Aitman TJ; Cooper LD; Norsworthy PJ; Wahid FN; Gray JK; Curtis BR; McKeigue PM; Kwiatkowski D; et alGreenwood BM; Snow RW; Hill AV; Scott J. (29 Jun 2000). Malaria susceptibility and CD36 mutation. Nature. 405:1015-1016. DOI.
• Somasekaram A; Jarmuz A; How A; Scott J; Navaratnam N. (1 Oct 1999). Intracellular localization of human cytidine deaminase - Identification of a functional nuclear localization signal. J BIOL CHEM. 274:28405-28412.
• Scott J. (26 Aug 1999). Heart disease - Good cholesterol news. NATURE. 400:816-+.
• Fujino T; Navaratnam N; Jarmuz A; von Haeseler A; Scott J. (1 Jul 1999). C -> U editing of apolipoprotein B mRNA in marsupials: identification and characterisation of APOBEC-1 from the American opossum Monodelphus domestica. NUCLEIC ACIDS RES. 27:2662-2671.
• Scott J; Navaratnam N; Carter C. (Jul 1999). Molecular modelling of the biosynthesis of the RNA-editing enzyme APOBEC-1, responsible for generating the alternative forms of apolipoprotein B. Exp Physiol. 84:791-800.
• Al-Majali KM; Glazier AM; Norsworthy PJ; Wahid FN; Cooper LD; Wallace CA; Scott J; Lausen B; et alAitman TJ. (May 1999). A high-resolution radiation hybrid map of the proximal region of rat Chromosome 4. MAMM GENOME. 10:471-476.
• Ritchie PJ; Decout A; Amey J; Mann CJ; Read J; Rosseneu M; Scott J; Shoulders CC. (1 Mar 1999). Baculovirus expression and biochemical characterization of the human microsomal triglyceride transfer protein. Biochem J. 338 ( Pt 2):305-310.
• Bradbury P; Mann CJ; Köchl S; Anderson TA; Chester SA; Hancock JM; Ritchie PJ; Amey J; et alHarrison GB; Levitt DG; Banaszak LJ; Scott J; Shoulders CC. (29 Jan 1999). A common binding site on the microsomal triglyceride transfer protein for apolipoprotein B and protein disulfide isomerase. J Biol Chem. 274:3159-3164.
• Nicodeme E; Benoist F; McLeod R; Yao ZM; Scott J; Shoulders CC; Grand-Perret T. (22 Jan 1999). Identification of domains in apolipoprotein B100 that confer a high requirement for the microsomal triglyceride transfer protein. J BIOL CHEM. 274:1986-1993.
• Mann CJ; Anderson TA; Read J; Chester SA; Harrison GB; Kochl S; Ritchie PJ; Bradbury P; et alHussain FS; Amey J; Vanloo B; Rosseneu M; Infante R; Hancock JM; Levitt DG; Banaszak LJ; Scott J; Shoulders CC. (8 Jan 1999). The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins. J MOL BIOL. 285:391-408.
• Aitman TJ; Glazier AM; Wallace CA; Cooper LD; Norsworthy PJ; Wahid FN; Al-Majali KM; Trembling PM; et alMann CJ; Shoulders CC; Graf D; St Lezin E; Kurtz TW; Kren V; Pravenec M; Ibrahimi A; Abumrad NA; Stanton LW; Scott J. (Jan 1999). Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nat Genet. 21:76-83. DOI.
• Scott J; Navaratnam N; Carter C. (Dec 1998). Molecular modelling and the biosynthesis of apolipoprotein B containing lipoproteins. ATHEROSCLEROSIS. 141:S17-S24.
• Richardson N; Navaratnam N; Scott J. (27 Nov 1998). Secondary structure for the apolipoprotein B mRNA editing site. Au-binding proteins interact with a stem loop. J Biol Chem. 273:31707-31717.
• Aitman TJ; Pravenec M; Kurtz TW; Scott J. (Nov 1998). The spontaneously hypertensive rat: a model to dissect cellular defects in glucose and fatty acid metabolism. PATHOL BIOL. 46:693-694.
• Kooner JS; Baliga RR; Wilding J; Crook D; Packard CJ; Banks LM; Peart S; Aitman TJ; et alScott J. (Jul 1998). Abdominal obesity, impaired nonesterified fatty acid suppression, and insulin-mediated glucose disposal are early metabolic abnormalities in families with premature myocardial infarction. Arterioscler Thromb Vasc Biol. 18:1021-1026.
• Navaratnam N; Fujino T; Bayliss J; Jarmuz A; How A; Richardson N; Somasekaram A; Bhattacharya S; et alCarter C; Scott J. (30 Jan 1998). Escherichia coli cytidine deaminase provides a molecular model for ApoB RNA editing and a mechanism for RNA substrate recognition. J MOL BIOL. 275:695-714.
• Fujino T; Navaratnam N; Scott J. (15 Jan 1998). Human apolipoprotein B RNA editing deaminase gene (APOBEC1). Genomics. 47:266-275. DOI.
• Heath KE; Luong LA; Leonard JV; Chester A; Shoulders CC; Scott J; Middleton-Price HR; Humphries SE; et alTalmud PJ. (Dec 1997). The use of a highly informative CA repeat polymorphism within the abetalipoproteinaemia locus (4q22-24). PRENATAL DIAG. 17:1181-1186.
• Gotoda T; Scott J; Aitman TJ. (Aug 1997). Molecular screening of the human melanocortin-4 receptor gene: identification of a missense variant showing no association with obesity, plasma glucose, or insulin. Diabetologia. 40:976-979. DOI.
• Shovlin CL; Hughes JMB; Scott J; Seidman CE; Seidman JG. (Jul 1997). Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia. AM J HUM GENET. 61:68-79.
• Gotoda T; Manning BS; Goldstone AP; Imrie H; Evans AL; Strosberg AD; McKeigue PM; Scott J; et alAitman TJ. (Jun 1997). Leptin receptor gene variation and obesity: Lack of association in a white British male population. HUM MOL GENET. 6:869-876.
• Aitman TJ; Gotoda T; Evans AL; Imrie H; Heath KE; Trembling PM; Truman H; Wallace CA; et alRahman A; Doré C; Flint J; Kren V; Zidek V; Kurtz TW; Pravenec M; Scott J. (Jun 1997). Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats. Nat Genet. 16:197-201. DOI.
• Scott J. (15 May 1997). RNA editing - Message change for a fat controller. NATURE. 387:242-243.
• Thompson GR; Scott J; Walport MJ; Oakley CM; Hughes JMB; Bulpitt CJ; TaylorRobinson SD. (5 Apr 1997). Grand rounds - Hammersmith Hospital - Hazards of running a marathon - Creatine kinase MB can be raised without myocardial infarction. BRIT MED J. 314:1023-1025.
• Aitman TJ; Godsland IF; Farren B; Crook D; Wong HJ; Scott J. (Apr 1997). Defects of insulin action on fatty acid and carbohydrate metabolism in familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol. 17:748-754.
• Kreuzer J; White AL; Knott TJ; Jien ML; Mehrabian M; Scott J; Young SG; Haberland ME. (Feb 1997). Amino terminus of apolipoprotein B suffices to produce recognition of malondialdehyde-modified low density lipoprotein by the scavenger receptor of human monocyte-macrophages. J Lipid Res. 38:324-342.
• Woods A; Salt I; Scott J; Hardie DG; Carling D. (18 Nov 1996). The alpha1 and alpha2 isoforms of the AMP-activated protein kinase have similar activities in rat liver but exhibit differences in substrate specificity in vitro. FEBS Lett. 397:347-351.
• Leiper JM; Harrison GB; Bayliss J; Scott JD; Pease RJ. (Oct 1996). Systematic expression of the complete coding sequence of apoB-100 does not reveal transmembrane determinants. J Lipid Res. 37:2215-2231.
• Morrison JR; Paszty C; Stevens ME; Hughes SD; Forte T; Scott J; Rubin EM. (9 Jul 1996). Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism. P NATL ACAD SCI USA. 93:7154-7159.
• Baliga R; Lammertsma A; Rhodes C; Aitman T; Scott J; Kooner JS. (May 1996). Positron emission tomography localises insulin resistance to skeletal muscle in premature coronary heart disease. HEART. 75:48-48.
• Woods A; Cheung PC; Smith FC; Davison MD; Scott J; Beri RK; Carling D. (26 Apr 1996). Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro. J Biol Chem. 271:10282-10290.
• AlMohammad A; Scott J; Beatt KJ; MacDermot J; Davies K; Aitman T; Clutterbuck E; Beynon H; et alNoble MIM. (20 Apr 1996). Grand Rounds - Hammersmith Hospital - A physiology classic revisited after 60 years. BRIT MED J. 312:1029-1031.
• Lamberg A; Jauhiainen M; Metso J; Ehnholm C; Shoulders C; Scott J; Pihlajaniemi T; Kivirikko KI. (15 Apr 1996). The role of protein disulphide isomerase in the microsomal triacylglycerol transfer protein does not reside in its isomerase activity. BIOCHEM J. 315:533-536.
• Scott J. (11 Jan 1996). New chapter for the fat controller. Nature. 379:113-114. DOI.
• Hughes SD; Rouy D; Navaratnam N; Scott J; Rubin EM. (Jan 1996). Gene transfer of cytidine deaminase apoBEC-1 lowers lipoprotein(a) in transgenic mice and induces apolipoprotein B editing in rabbits. HUM GENE THER. 7:39-49.
• Shovlin CL; Scott J. (1996). Inherited diseases of the vasculature. ANNU REV PHYSIOL. 58:483-507.
• NARCISI TME; SHOULDERS CC; CHESTER SA; READ J; BRETT DJ; HARRISON GB; GRANTHAM TT; FOX MF; et alPOVEY S; DEBRUIN TWA; ERKELENS DW; MULLER DPR; LLOYD JK; SCOTT J. (Dec 1995). MUTATIONS OF THE MICROSOMAL TRIGLYCERIDE-TRANSFER-PROTEIN GENE IN ABETALIPOPROTEINEMIA. AM J HUM GENET. 57:1298-1310.
• BALIGA R; LAMMERTSMA A; RHODES C; AITMAN T; SCOTT J; KOONER JS. (15 Oct 1995). POSITRON EMISSION TOMOGRAPHY LOCALIZES INSULIN-RESISTANCE TO SKELETAL-MUSCLE IN PREMATURE CORONARY HEART-DISEASE. CIRCULATION. 92:77-77.
• KOONER JS; BALIGA RR; WILDING J; PEART S; AITMAN TJ; SCOTT J. (15 Oct 1995). METABOLIC PHENOTYPES FOR GENETIC-ANALYSIS IN CORONARY HEART-DISEASE. CIRCULATION. 92:76-76.
• Brett DJ; Pease RJ; Scott J; Gibbons GF. (15 Aug 1995). Microsomal triglyceride transfer protein activity remains unchanged in rat livers under conditions of altered very-low-density lipoprotein secretion. Biochem J. 310 ( Pt 1):11-14.
• SCOTT J. (16 Jun 1995). A PLACE IN THE WORLD FOR RNA EDITING. CELL. 81:833-836.
• NAVARATNAM N; BHATTACHARYA S; FUJINO T; PATEL D; JARMUZ AL; SCOTT J. (21 Apr 1995). EVOLUTIONARY ORIGINS OF APO-B MESSENGER-RNA EDITING - CATALYSIS BY A CYTIDINE DEAMINASE THAT HAS ACQUIRED A NOVEL RNA-BINDING MOTIF AT ITS ACTIVE-SITE. CELL. 81:187-195.
• Scott J; Hobbs HH. (Apr 1995). Genetics and molecular biology. Curr Opin Lipidol. 6:67-69.
• Pease RJ; Leiper JM; Harrison GB; Scott J. (31 Mar 1995). Studies on the translocation of the amino terminus of apolipoprotein B into the endoplasmic reticulum. J Biol Chem. 270:7261-7271.
• Verhoeven AJ; Woods A; Brennan CH; Hawley SA; Hardie DG; Scott J; Beri RK; Carling D. (1 Mar 1995). The AMP-activated protein kinase gene is highly expressed in rat skeletal muscle. Alternative splicing and tissue distribution of the mRNA. Eur J Biochem. 228:236-243.
• DAVIDSON NO; INNERARITY TL; SCOTT J; SMITH H; DRISCOLL DM; TENG B; CHAN L. (Mar 1995). PROPOSED NOMENCLATURE FOR THE CATALYTIC SUBUNIT OF THE MAMMALIAN APOLIPOPROTEIN-B MESSENGER-RNA EDITING ENZYME - APOBEC-1. RNA. 1:3-3.
• Greeve J; Scott J. (1995). In vitro mRNA editing using S100 extracts. Methods Mol Biol. 37:77-87. DOI.
• Beri RK; Marley AE; See CG; Sopwith WF; Aguan K; Carling D; Scott J; Carey F. (12 Dec 1994). Molecular cloning, expression and chromosomal localisation of human AMP-activated protein kinase. FEBS Lett. 356:117-121.
• TENG BB; BLUMENTHAL S; FORTE T; NAVARATNAM N; SCOTT J; GOTTO AM; CHAN L. (25 Nov 1994). ADENOVIRUS-MEDIATED GENE-TRANSFER OF RAT APOLIPOPROTEIN-B MESSENGER-RNA-EDITING PROTEIN IN MICE VIRTUALLY ELIMINATES APOLIPOPROTEIN B-100 AND NORMAL LOW-DENSITY-LIPOPROTEIN PRODUCTION. J BIOL CHEM. 269:29395-29404.
• Aguan K; Scott J; See CG; Sarkar NH. (18 Nov 1994). Characterization and chromosomal localization of the human homologue of a rat AMP-activated protein kinase-encoding gene: a major regulator of lipid metabolism in mammals. Gene. 149:345-350.
• HUGHES SD; ROUY D; NAVARA N; SCOTT J; RUBIN EM. (Oct 1994). INTRODUCTION OF APOLIPOPROTEIN-B MESSENGER-RNA EDITING FACTOR P27 INCREASES IN-VIVO HEPATIC APO-B EDITING IN RABBITS AND MICE. CIRCULATION. 90:1-1.
• Leiper JM; Bayliss JD; Pease RJ; Brett DJ; Scott J; Shoulders CC. (2 Sep 1994). Microsomal triglyceride transfer protein, the abetalipoproteinemia gene product, mediates the secretion of apolipoprotein B-containing lipoproteins from heterologous cells. J Biol Chem. 269:21951-21954.
• Cullen P; Farren B; Scott J; Farrall M. (Aug 1994). Complex segregation analysis provides evidence for a major gene acting on serum triglyceride levels in 55 British families with familial combined hyperlipidemia. Arterioscler Thromb. 14:1233-1249.
• Woods A; Munday MR; Scott J; Yang X; Carlson M; Carling D. (29 Jul 1994). Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. J Biol Chem. 269:19509-19515.
• Shoulders CC; Narcisi TM; Read J; Chester A; Brett DJ; Scott J; Anderson TA; Levitt DG; et alBanaszak LJ. (May 1994). The abetalipoproteinemia gene is a member of the vitellogenin family and encodes an alpha-helical domain. Nat Struct Biol. 1:285-286.
• Carling D; Aguan K; Woods A; Verhoeven AJ; Beri RK; Brennan CH; Sidebottom C; Davison MD; et alScott J. (15 Apr 1994). Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism. J Biol Chem. 269:11442-11448.
• Scott J; Navaratnam N; Bhattacharya S; Morrison JR. (Apr 1994). The apolipoprotein B messenger RNA editing enzyme. Curr Opin Lipidol. 5:87-93.
• Bhattacharya S; Navaratnam N; Morrison JR; Scott J; Taylor WR. (Mar 1994). Cytosine nucleoside/nucleotide deaminases and apolipoprotein B mRNA editing. Trends Biochem Sci. 19:105-106.
• Perraudeau M; Scott J; Walport M; Oakley C; Bloom S; Brooks D. (19 Feb 1994). Late presentation of Kartagener's syndrome. Consequences of ciliary dysfunction. BMJ. 308:519-521.
• Shovlin CL; Hughes JM; Tuddenham EG; Temperley I; Perembelon YF; Scott J; Seidman CE; Seidman JG. (Feb 1994). A gene for hereditary haemorrhagic telangiectasia maps to chromosome 9q3. Nat Genet. 6:205-209. DOI.
• SHOULDERS CC; BRETT DJ; BAYLISS JD; NARCISI TME; JARMUZ A; GRANTHAM TT; LEONI PRD; BHATTACHARYA S; et alPEASE RJ; CULLEN PM; LEVI S; BYFIELD PGH; PURKISS P; SCOTT J. (Dec 1993). ABETALIPOPROTEINEMIA IS CAUSED BY DEFECTS OF THE GENE ENCODING THE 97 KDA SUBUNIT OF A MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN. HUM MOL GENET. 2:2109-2116.
• Lord GM; Scott J; Pusey CD; Rees AJ; Walport MJ; Davies KA; Bulpitt C; Bloom SR; et alMuntoni FM. (30 Oct 1993). Diabetes and rhabdomyolysis. A rare complication of a common disease. BMJ. 307:1126-1128.
• Clifford CP; Davies GJ; Scott J; Shaunak S; Sarvill J; Schofield JB. (23 Oct 1993). Tuberculous pericarditis with rapid progression to constriction. Prompt diagnosis and treatment are needed. BMJ. 307:1052-1054.
• Navaratnam N; Morrison JR; Bhattacharya S; Patel D; Funahashi T; Giannoni F; Teng BB; Davidson NO; et alScott J. (5 Oct 1993). The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase. J Biol Chem. 268:20709-20712.
• Narcisi TM; Schotz MC; Scott J; Shoulders CC. (1 Oct 1993). Dinucleotide repeat polymorphisms at the lipoprotein lipase (LPL) locus. Hum Genet. 92:312-313.
• Scott J. (18 Sep 1993). Apolipoprotein E and Alzheimer's disease. Lancet. 342:696.
• Venkatesan S; Cullen P; Pacy P; Halliday D; Scott J. (Jul 1993). Stable isotopes show a direct relation between VLDL apoB overproduction and serum triglyceride levels and indicate a metabolically and biochemically coherent basis for familial combined hyperlipidemia. Arterioscler Thromb. 13:1110-1118.
• Scott J. (22 May 1993). Nature, nurture, and hypercholesterolaemia. Lancet. 341:1312-1313.
• Shoulders CC; Narcisi TM; Jarmuz A; Brett DJ; Bayliss JD; Scott J. (Mar 1993). Characterization of genetic markers in the 5'flanking region of the apo A1 gene. Hum Genet. 91:197-198.
• Navaratnam N; Shah R; Patel D; Fay V; Scott J. (1 Jan 1993). Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site. Proc Natl Acad Sci U S A. 90:222-226.
• SCOTT J. (17 Dec 1992). MEDICAL GENETICS - ARTERIAL HARDENING IN MICE. NATURE. 360:631-632.
• PATEL SB; PESSAH M; BEUCLER I; SCOTT J; NAVARRO J; INFANTE R. (Oct 1992). DETECTION OF NORMALLY EDITED APOLIPOPROTEIN-B MESSENGER-RNA IN ANDERSON DISEASE - A DEFECT OF LIPOPROTEIN ASSEMBLY. CIRCULATION. 86:208-208.
• White AL; Graham DL; LeGros J; Pease RJ; Scott J. (5 Aug 1992). Oleate-mediated stimulation of apolipoprotein B secretion from rat hepatoma cells. A function of the ability of apolipoprotein B to direct lipoprotein assembly and escape presecretory degradation. J Biol Chem. 267:15657-15664.
• Borén J; Graham L; Wettesten M; Scott J; White A; Olofsson SO. (15 May 1992). The assembly and secretion of ApoB 100-containing lipoproteins in Hep G2 cells. ApoB 100 is cotranslationally integrated into lipoproteins. J Biol Chem. 267:9858-9867.
• PEASE R; HARRISON G; LEIPER J; SCOTT J. (12 Mar 1992). APOLIPOPROTEIN-B INTERMEDIATES - REPLY. NATURE. 356:115-116.
• Hodges P; Scott J. (Feb 1992). Apolipoprotein B mRNA editing: a new tier for the control of gene expression. Trends Biochem Sci. 17:77-81.
• Pease RJ; Harrison GB; Scott J. (3 Oct 1991). Cotranslocational insertion of apolipoprotein B into the inner leaflet of the endoplasmic reticulum. Nature. 353:448-450. DOI.
• Bhattacharya S; Ameis D; Cullen P; Narcisi TM; Bayliss J; Greten H; Schotz MC; Scott J. (25 Sep 1991). VNTR polymorphism in the hepatic lipase gene (LIPC). Nucleic Acids Res. 19:5088.
• Bhattacharya S; Wilson TM; Wojciechowski AP; Volpe CP; Scott J. (11 Sep 1991). Hypervariable polymorphism in the APOC3 gene. Nucleic Acids Res. 19:4799.
• Shah RR; Knott TJ; Legros JE; Navaratnam N; Greeve JC; Scott J. (5 Sep 1991). Sequence requirements for the editing of apolipoprotein B mRNA. J Biol Chem. 266:16301-16304.
• Greeve J; Navaratnam N; Scott J. (11 Jul 1991). Characterization of the apolipoprotein B mRNA editing enzyme: no similarity to the proposed mechanism of RNA editing in kinetoplastid protozoa. Nucleic Acids Res. 19:3569-3576.
• Graham DL; Knott TJ; Jones TC; Pease RJ; Pullinger CR; Scott J. (4 Jun 1991). Carboxyl-terminal truncation of apolipoprotein B results in gradual loss of the ability to form buoyant lipoproteins in cultured human and rat liver cell lines. Biochemistry. 30:5616-5621.
• Navaratnam N; Patel D; Shah RR; Greeve JC; Powell LM; Knott TJ; Scott J. (25 Apr 1991). An additional editing site is present in apolipoprotein B mRNA. Nucleic Acids Res. 19:1741-1744.
• Hodges PE; Navaratnam N; Greeve JC; Scott J. (25 Mar 1991). Site-specific creation of uridine from cytidine in apolipoprotein B mRNA editing. Nucleic Acids Res. 19:1197-1201.
• Wojciechowski AP; Farrall M; Cullen P; Wilson TM; Bayliss JD; Farren B; Griffin BA; Caslake MJ; et alPackard CJ; Shepherd J. (10 Jan 1991). Familial combined hyperlipidaemia linked to the apolipoprotein AI-CII-AIV gene cluster on chromosome 11q23-q24. Nature. 349:161-164. DOI.
• Borén J; White A; Wettesten M; Scott J; Graham L; Olofsson SO. (1991). The molecular mechanism for the assembly and secretion of ApoB-100-containing lipoproteins. Prog Lipid Res. 30:205-218.
• Kunitake ST; Young SG; Chen GC; Pullinger CR; Zhu S; Pease RJ; Scott J; Hass P; et alSchilling J; Kane JP. (5 Dec 1990). Conformation of apolipoprotein B-100 in the low density lipoproteins of tangier disease. Identification of localized conformational response to triglyceride content. J Biol Chem. 265:20739-20746.
• Law A; Scott J. (Jun 1990). A cross-species comparison of the apolipoprotein B domain that binds to the LDL receptor. J Lipid Res. 31:1109-1120.
• Scott J. (Apr 1990). RNA editing: a novel mechanism for the regulation of dietary cholesterol absorption. The Humphry Davy Rolleston lecture 1989. J R Coll Physicians Lond. 24:101-106.
• Jessup W; Rankin SM; De Whalley CV; Hoult JR; Scott J; Leake DS. (15 Jan 1990). Alpha-tocopherol consumption during low-density-lipoprotein oxidation. Biochem J. 265:399-405.
• Pease RJ; Milne RW; Jessup WK; Law A; Provost P; Fruchart JC; Dean RT; Marcel YL; et alScott J. (5 Jan 1990). Use of bacterial expression cloning to localize the epitopes for a series of monoclonal antibodies against apolipoprotein B100. J Biol Chem. 265:553-568.
• Scott J. (Dec 1989). Messenger RNA editing and modification. Curr Opin Cell Biol. 1:1141-1147.
• Milne R; Théolis R; Maurice R; Pease RJ; Weech PK; Rassart E; Fruchart JC; Scott J; et alMarcel YL. (25 Nov 1989). The use of monoclonal antibodies to localize the low density lipoprotein receptor-binding domain of apolipoprotein B. J Biol Chem. 264:19754-19760.
• Scott J. (7 Sep 1989). Lipoprotein(a). Thrombogenesis linked to atherogenesis at last?. Nature. 341:22-23. DOI.
• Davies MS; Wallis SC; Driscoll DM; Wynne JK; Williams GW; Powell LM; Scott J. (15 Aug 1989). Sequence requirements for apolipoprotein B RNA editing in transfected rat hepatoma cells. J Biol Chem. 264:13395-13398.
• Driscoll DM; Wynne JK; Wallis SC; Scott J. (11 Aug 1989). An in vitro system for the editing of apolipoprotein B mRNA. Cell. 58:519-525.
• Pullinger CR; North JD; Teng BB; Rifici VA; Ronhild de Brito AE; Scott J. (Jul 1989). The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life. J Lipid Res. 30:1065-1077.
• Rajput-Williams J; Eyre J; Nanjee MN; Crook D; Scott J; Miller NE. (May 1989). Plasma lipoprotein lipids in relation to the MspI polymorphism of the apolipoprotein AII gene in Caucasian men. Lack of association with plasma triglyceride concentration. Atherosclerosis. 77:31-36.
• Scott J. (9 Mar 1989). Lipoprotein receptors. Unravelling atherosclerosis. Nature. 338:118-119. DOI.
• Scott J. (Feb 1989). The molecular and cell biology of apolipoprotein-B. Mol Biol Med. 6:65-80.
• Jones T; Rajput-Williams J; Knott TJ; Scott J. (11 Jan 1989). An MspI RFLP in the APOB promoter. Nucleic Acids Res. 17:472.
• Rajput-Williams J; Knott TJ; Wallis SC; Sweetnam P; Yarnell J; Cox N; Bell GI; Miller NE; et alScott J. (24 Dec 1988). Variation of apolipoprotein-B gene is associated with obesity, high blood cholesterol levels, and increased risk of coronary heart disease. Lancet. 2:1442-1446.
• Talmud PJ; Lloyd JK; Muller DP; Collins DR; Scott J; Humphries S. (Nov 1988). Genetic evidence from two families that the apolipoprotein B gene is not involved in abetalipoproteinemia. J Clin Invest. 82:1803-1806. DOI.
• Davidson NO; Powell LM; Wallis SC; Scott J. (25 Sep 1988). Thyroid hormone modulates the introduction of a stop codon in rat liver apolipoprotein B messenger RNA. J Biol Chem. 263:13482-13485.
• COLLINS DR; KNOTT TJ; PEASE RJ; POWELL LM; WALLIS SC; ROBERTSON S; PULLINGER CR; MILNE RW; et alMARCEL YL; HUMPHRIES SE; TALMUD PJ; LLOYD JK; MILLER NE; MULLER D; SCOTT J. (12 Sep 1988). TRUNCATED VARIANTS OF APOLIPOPROTEIN-B CAUSE HYPOBETALIPOPROTEINEMIA. NUCLEIC ACIDS RES. 16:8361-8375.
• Middleton-Price HR; van den Berghe JA; Scott J; Knott TJ; Malcolm S. (Jul 1988). Regional chromosomal localisation of APOA2 to 1q21-1q23. Hum Genet. 79:283-285.
• Krul ES; Kleinman Y; Kinoshita M; Pfleger B; Oida K; Law A; Scott J; Pease R; et alSchonfeld G. (Jul 1988). Regional specificities of monoclonal anti-human apolipoprotein B antibodies. J Lipid Res. 29:937-947.
• (21 May 1988). Apolipoprotein-B and atherogenesis. Lancet. 1:1141-1142.
• Kessling AM; Rajput-Wiliams J; Bainton D; Scott J; Miller NE; Baker I; Humphries SE. (Mar 1988). DNA polymorphisms of the apolipoprotein AII and AI-CIII-AIV genes: a study in men selected for differences in high-density-lipoprotein cholesterol concentration. Am J Hum Genet. 42:458-467.
• Rorsman F; Bywater M; Knott TJ; Scott J; Betsholtz C. (Feb 1988). Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins. Mol Cell Biol. 8:571-577.
• Scott J. (26 Sep 1987). Molecular genetics of common diseases. Br Med J (Clin Res Ed). 295:769-771.
• Powell LM; Wallis SC; Pease RJ; Edwards YH; Knott TJ; Scott J. (11 Sep 1987). A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine. Cell. 50:831-840.
• Ludwig EH; Blackhart BD; Pierotti VR; Caiati L; Fortier C; Knott T; Scott J; Mahley RW; et alLevy-Wilson B; McCarthy BJ. (Aug 1987). DNA sequence of the human apolipoprotein B gene. DNA. 6:363-372.
• Betsholtz C; Bergh J; Bywater M; Pettersson M; Johnsson A; Heldin CH; Ohlsson R; Knott TJ; et alScott J; Bell GI. (15 Apr 1987). Expression of multiple growth factors in a human lung cancer cell line. Int J Cancer. 39:502-507.
• Scott J. (12 Feb 1987). Oncogenes in atherosclerosis. Nature. 325:574-575. DOI.
• Scott J; Pease RJ; Powell LM; Wallis SC; McCarthy BJ; Mahley RW; Levy-Wilson B; Knott TJ. (1987). Apolipoprotein B gene: plasma cholesterol and atherosclerosis. Biochem Soc Symp. 53:155-163.
• Knott TJ; Wallis SC; Pease RJ; Powell LM; Scott J. (25 Nov 1986). A hypervariable region 3' to the human apolipoprotein B gene. Nucleic Acids Res. 14:9215-9216.
• Blackhart BD; Ludwig EM; Pierotti VR; Caiati L; Onasch MA; Wallis SC; Powell L; Pease R; et alKnott TJ; Chu ML. (25 Nov 1986). Structure of the human apolipoprotein B gene. J Biol Chem. 261:15364-15367.
• Knott TJ; Pease RJ; Powell LM; Wallis SC; Rall SC; Innerarity TL; Blackhart B; Taylor WH; et alMarcel Y; Milne R. (23 Oct 1986). Complete protein sequence and identification of structural domains of human apolipoprotein B. Nature. 323:734-738. DOI.
• Forgez P; Gregory H; Young JA; Knott T; Scott J; Chapman MJ. (15 Oct 1986). Identification of surface-exposed segments of apolipoprotein B-100 in the LDL particle. Biochem Biophys Res Commun. 140:250-257.
• Berg K; Powell LM; Wallis SC; Pease R; Knott TJ; Scott J. (Oct 1986). Genetic linkage between the antigenic group (Ag) variation and the apolipoprotein B gene: assignment of the Ag locus. Proc Natl Acad Sci U S A. 83:7367-7370.
• Knott TJ; Wallis SC; Powell LM; Pease RJ; Lusis AJ; Blackhart B; McCarthy BJ; Mahley RW; et alLevy-Wilson B; Scott J. (25 Sep 1986). Complete cDNA and derived protein sequence of human apolipoprotein B-100. Nucleic Acids Res. 14:7501-7503.
• Law A; Wallis SC; Powell LM; Pease RJ; Brunt H; Priestley LM; Knott TJ; Scott J; et alAltman DG; Miller GJ. (7 Jun 1986). Common DNA polymorphism within coding sequence of apolipoprotein B gene associated with altered lipid levels. Lancet. 1:1301-1303.
• Lusis AJ; Heinzmann C; Sparkes RS; Scott J; Knott TJ; Geller R; Sparkes MC; Mohandas T. (Jun 1986). Regional mapping of human chromosome 19: organization of genes for plasma lipid transport (APOC1, -C2, and -E and LDLR) and the genes C3, PEPD, and GPI. Proc Natl Acad Sci U S A. 83:3929-3933.
• Betsholtz C; Johnsson A; Heldin CH; Westermark B; Lind P; Urdea MS; Eddy R; Shows TB; et alPhilpott K; Mellor AL. (24 Apr 1986). cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines. Nature. 320:695-699. DOI.
• Knott TJ; Rall SC; Innerarity TL; Jacobson SF; Urdea MS; Levy-Wilson B; Powell LM; Pease RJ; et alEddy R; Nakai H. (4 Oct 1985). Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization. Science. 230:37-43.
• Priestley L; Knott T; Wallis S; Powell L; Pease R; Scott J. (25 Sep 1985). RFLP for the human apolipoprotein B gene: IV;MspI. Nucleic Acids Res. 13:6792.
• Priestley L; Knott T; Wallis S; Powell L; Pease R; Scott J. (25 Sep 1985). RFLP for the human apolipoprotein B gene: III;EcoRV. Nucleic Acids Res. 13:6791.
• Priestley L; Knott T; Wallis S; Powell L; Pease R; Scott J. (25 Sep 1985). RFLP for the human apolipoprotein B gene: II;EcoRI. Nucleic Acids Res. 13:6790.
• Priestley L; Knott T; Wallis S; Powell L; Pease R; Brunt H; Scott J. (25 Sep 1985). RFLP for the human apolipoprotein B gene: V;XbaI. Nucleic Acids Res. 13:6793.
• Priestley L; Knott T; Wallis S; Powell L; Pease R; Simon A; Scott J. (25 Sep 1985). RFLP for the human apolipoprotein B gene: I;BamHI. Nucleic Acids Res. 13:6789.
• Scott J; Cowell J; Robertson ME; Priestley LM; Wadey R; Hopkins B; Pritchard J; Bell GI; et alRall LB; Graham CF. (19 Sep 1985). Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues. Nature. 317:260-262.
• Knott TJ; Wallis SC; Robertson ME; Priestley LM; Urdea M; Rall LB; Scott J. (11 Sep 1985). The human apolipoprotein AII gene: structural organization and sites of expression. Nucleic Acids Res. 13:6387-6398.
• Wion D; Barrand P; Dicou E; Scott J; Brachet P. (9 Sep 1985). Serum and thyroid hormones T3 and T4 regulate nerve growth factor mRNA levels in mouse L cells. FEBS Lett. 189:37-41.
• (3 Aug 1985). Polypeptide growth factors: a clinical perspective. Lancet. 2:251-253.
• Korsching S; Auburger G; Heumann R; Scott J; Thoenen H. (Jun 1985). Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J. 4:1389-1393.
• Bell GI; Rall LB; Sanchez-Pescador R; Merryweather JP; Scott J; Eddy RL; Shows TB. (May 1985). Human alpha 2-macroglobulin gene is located on chromosome 12. Somat Cell Mol Genet. 11:285-289.
• Scott J; Knott TJ; Priestley LM; Robertson ME; Mann DV; Kostner G; Miller GJ; Miller NE. (6 Apr 1985). High-density lipoprotein composition is altered by a common DNA polymorphism adjacent to apoprotein AII gene in man. Lancet. 1:771-773.
• Rall LB; Scott J; Bell GI; Crawford RJ; Penschow JD; Niall HD; Coghlan JP. (17 Jan 1985). Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues. Nature. 313:228-231.
• Zabel BU; Eddy RL; Lalley PA; Scott J; Bell GI; Shows TB. (Jan 1985). Chromosomal locations of the human and mouse genes for precursors of epidermal growth factor and the beta subunit of nerve growth factor. Proc Natl Acad Sci U S A. 82:469-473.
• Scott J; Knott TJ; Shaw DJ; Brook JD. (1985). Localization of genes encoding apolipoproteins CI, CII, and E to the p13----cen region of human chromosome 19. Hum Genet. 71:144-146.
• Scott J; Patterson S; Rall L; Bell GI; Crawford R; Penschow J; Niall H; Coghlan J. (1985). The structure and biosynthesis of epidermal growth factor precursor. J Cell Sci Suppl. 3:19-28.
• Heumann R; Korsching S; Scott J; Thoenen H. (20 Dec 1984). Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J. 3:3183-3189.
• Knott TJ; Eddy RL; Robertson ME; Priestley LM; Scott J; Shows TB. (30 Nov 1984). Chromosomal localization of the human apoprotein CI gene and of a polymorphic apoprotein AII gene. Biochem Biophys Res Commun. 125:299-306.
• Bell GI; Merryweather JP; Sanchez-Pescador R; Stempien MM; Priestley L; Scott J; Rall LB. (30 Aug 1984). Sequence of a cDNA clone encoding human preproinsulin-like growth factor II. Nature. 310:775-777.
• Tricoli JV; Rall LB; Scott J; Bell GI; Shows TB. (30 Aug 1984). Localization of insulin-like growth factor genes to human chromosomes 11 and 12. Nature. 310:784-786.
• Knott TJ; Priestley LM; Urdea M; Scott J. (16 May 1984). Isolation and characterisation of a cDNA encoding the precursor for human apolipoprotein AII. Biochem Biophys Res Commun. 120:734-740.
• Knott TJ; Robertson ME; Priestley LM; Urdea M; Wallis S; Scott J. (11 May 1984). Characterisation of mRNAs encoding the precursor for human apolipoprotein CI. Nucleic Acids Res. 12:3909-3915.
• Scott J; Urdea M; Quiroga M; Sanchez-Pescador R; Fong N; Selby M; Rutter WJ; Bell GI. (15 Jul 1983). Structure of a mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins. Science. 221:236-240.
• Cooper BT; Scott J; Hopkins J; Peters TJ. (May 1983). Adult onset sucrase-isomaltase deficiency with secondary disaccharidase deficiency resulting from severe dietary carbohydrate restriction. Dig Dis Sci. 28:473-477.
• Scott J; Peters TJ. (May 1983). Protection of epithelial function in human jejunum cultured with hydrocortisone. Am J Physiol. 244:G532-G540.
• Scott J; Selby M; Urdea M; Quiroga M; Bell GI; Rutter WJ. (7 Apr 1983). Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor. Nature. 302:538-540.
• SCOTT J; MAZE M; PETERS TJ. (1982). PREDNISOLONE ENHANCES AMINOPEPTIDASE TURNOVER IN ADULT-RAT SMALL-INTESTINE. BIOCHIM BIOPHYS ACTA. 719:464-473.
• Batt RM; Scott J. (1982). Response of the small intestinal mucosa to oral glucocorticoids. Scand J Gastroenterol Suppl. 74:75-88.
• Elias E; Muller DP; Scott J. (12 Dec 1981). Association of spinocerebellar disorders with cystic fibrosis or chronic childhood cholestasis and very low serum vitamin E. Lancet. 2:1319-1321.
• Scott J; Batt RM; Maddison YE; Peters TJ. (Oct 1981). Differential effect of glucocorticoids on structure and function of adult rat jejunum. Am J Physiol. 241:G306-G312.
• Scott J. (Sep 1981). Physiological, pharmacological and pathological actions of glucocorticoids on the digestive system. Clin Gastroenterol. 10:627-652.
• Smith-Laing G; Scott J; Long RG; Dick R; Sherlock S. (May 1981). Role of percutaneous transhepatic obliteration of varices in the management of hemorrhage from gastroesophageal varices. Gastroenterology. 80:1031-1036.
• Scott J; Jenkins W; Smith GP; Peters TJ. (Feb 1981). Hepatic organelle pathology in primary biliary cirrhosis and the response to low-dose D-penicillamine therapy. Clin Sci (Lond). 60:207-212.
• Bramble MG; Watson AJ; Scott J; Peters TJ; Record CO. (1981). Clinical, biochemical and morphological responses of patients with villous atrophy to oral betamethasone valerate and clobetasone butyrate. Digestion. 22:281-288.
• Scott J; Shousha S; Thomas HC; Sherlock S. (Feb 1980). Bile duct carcinoma: a late complication of congenital hepatic fibrosis. Case report and review of literature. Am J Gastroenterol. 73:113-119.
• Summerfield JA; Scott J; Berman M; Ghent C; Bloomer JR; Berk PD; Sherlock S. (Feb 1980). Benign recurrent intrahepatic cholestasis: studies of bilirubin kinetics, bile acids, and cholangiography. Gut. 21:154-160.
• Scott J; Batt RM; Peters TJ. (Oct 1979). Enhancement of ileal adaptation by prednisolone after proximal small bowel resection in the rat. Gut. 20:858-864.
• Fitchett DH; Scott J; Stephens HR; Peters TJ. (May 1979). Myocardial subcellular fractionation studies on cardiomyopathic Syrian hamsters. Cardiovasc Res. 13:260-268.
• Batey R; Scott J; Jain S; Sherlock S. (Mar 1979). Acute renal insufficiency occurring during intravenous desferrioxamine therapy. Scand J Haematol. 22:277-279.
• Scott J; Gollan JL; Samourian S; Sherlock S. (Apr 1978). Wilson's disease, presenting as chronic active hepatitis. Gastroenterology. 74:645-651.
• SHOUSHA S; SCOTT J; POLAK J. (1978). ILEAL LOOP CARCINOMA AFTER CYSTECTOMY FOR BLADDER EXSTROPHY. BRIT MED J. 2:397-398.
• Ascione A; Elias E; Scott J; Sherlock S. (Jan 1978). Endoscopic retrograde cholangiography (ERC) in nonamebic liver abscesses. Am J Dig Dis. 23:39-44.
• Scott J; Elias E; Moult PJ; Barnes S; Wills MR. (Sep 1977). Rickets in adult cystic fibrosis with myopathy, pancreatic insufficiency and proximal renal tubular dysfunction. Am J Med. 63:488-492.
• Scott J; Summerfield JA; Elias E; Dick R; Sherlock S. (Mar 1977). Chronic pancreatitis: a cause of cholestasis. Gut. 18:196-201.
• Jain S; Long RG; Scott J; Dick R; Sherlock S. (Mar 1977). Percutaneous transhepatic cholangiography using the "Chiba" needle--80 cases. Br J Radiol. 50:175-180.
• Harding AE; Scott J; Jefferson M. (29 Jan 1977). Bladder rupture in multiple sclerosis. Br Med J. 1:270.
• (22 Jan 1977). Clinicopathological Conference. Diagnostic difficulties in a case of polypharmacy. Demonstrated at the Royal College of Physicians of London. Br Med J. 1:213-216.
• Scott J; Humphreys DR. (1 Jan 1977). Dissecting aortic aneurysm and disseminated intravascular coagulation. Br Med J. 1:24.
• Scott J; Dick R; Long RG; Sherlock S. (10 Jul 1976). Percutaneous transhepatic obliteration of gastro-oesophageal varices. Lancet. 2:53-55.
• Pettit JE; Scott J; Hussein S. (Apr 1976). EDTA dependent red cell neutrophil rosetting in autoimmune haemolytic anaemia. J Clin Pathol. 29:345-346.

Chapters in books

• Scott J. Ribonucleic acid (RNA). In McGraw-Hill Yearbook of Science & Technology 1998. 332-335. Staff MEOST (ed). McGraw-Hill Companies (Oct 1997).
• Scott J. Polygenic Disorders. In Molecular biology in medicine. 129-148. Cox TM (ed); Sinclair J (ed). Wiley-Blackwell, Oxford (1997).
• Scott J; Bhattacharya S; Navaratnam N; Patel D; Jarmuz AL. The catalytic subunit of the editing enzyme is a zinc-containing cytidine deaminase with an RNA-binding motif at its active site. In Atherosclerosis X. 949-952. Davignon J (ed); Woodford FP (ed); Sniderman A (ed). Elsevier Science Ltd (1995).
• Scott J. Apolipoprotein B and coronary heart disease. In From genetics to gene therapy. 7-23. Latchman DS (ed). Garland Science (1994).
• Hodges P; Scott J. Editing of Mammalian apolipoprotein B mRNA by site-specific RNA deamination. In RNA editing. 126-143. Benne R (ed). Ellis Horwood Ltd (1993).
• Scott J. The molecular biology of apolipoprotein B. In Cellular and molecular biology of atherosclerosis. 83-92. Gotto AM (ed). Springer, London (1992).
• Scott J. Molecular and cellular biology of apolipoprotein B. In Genetics of coronary heart disease. 99-113. Bearn AG (ed). Institute of Medical Genetics, Oslo (1992).
• Scott J; Wallis SC; Davies MS; Wynne JK; Powell LM; Driscoll DM. RNA editing: a novel mechanism for regulating lipid transport from the intestine. In From phenotype to gene in common disorders. 92-106. Berg K (ed); Retterstøl N (ed); Refsum S (ed). Mosby Elsevier Health Science, Copenhagen (1 Dec 1990).
• Scott J. The genetics of apolipoprotein-B. In Genetics and human nutrition. 187-197. Randle PJ (ed); Bell J (ed); Scott J (ed). John Libbey, London (1990).
• Powell LM; Davidson NO; Scott J. Apolipoprotein B: a novel mechanism for differential gene expression. In Platelets and vascular occlusion. 43-52. Patrono C (ed); FitzGerald GA (ed). Raven Pr, New York (1989).
• Scott J. The human apolipoprotein genes. In Oxford surveys on eukaryotic genes. 168-197. Maclean N (ed). Oxford University Press, USA (1988).
• Scott J; Selby MJ; Bell GI; Wallis SC; Pease RJ; Knott TJ; Powell L. Apolipoprotein B: a novel mechanism for deriving two proteins from one gene. In Hyperlipidaemia and atherosclerosis. 47-64. Suckling KE (ed); Groot PHE (ed). Academic Pr, London (1988).
• Scott J. New horizons in lipoprotein research. In Baillière's clinical endocrinology and metabolism. . Shepherd J (ed). Baillière Tindall, London (31 Dec 1987).
• Scott J; Knott TJ. The role of molecular biology in the assessment of the risk of atherosclerosis. In Pharmacological control of hyperlipidaemia. 491-508. Fears R (ed). JR Prous Science, Barcelona (1986).
• Coghlan JP; Aldred P; Butkus A; Crawford RJ; Darby IA; Fernley RT; Haralambidis J; Hudson PJ; et alMitri R; Niall HD; Penschow JD; Roche PJ; Scanlon DB; Tregear GW; Richards R; Van LB; Rall L; Scott J; Bell GI. Hybridization histochemistry. In Endocrinology. 18-24. Labrie F (ed); Proulx L (ed). Excerpta Medica ; New York : Distributors for Canada, Elsevier Science Pub. Co. (1984).
• Rutter WJ; Scott J; Selby M; Crawford RJ; Shen LP; Hobart P; Sanchez PR; Bell GI. Structure of precursors derived from the sequence of cloned cDNAs. In Biochemical and clinical aspects of neuropeptides: Synthesis, Processing and Gene Structure. 293-308. Koch G (ed); Richter D (ed). Academic Press, New York (1983).
• Batt RM; Scott J. Homeostatic control of cell proliferation in the small intestine: inhibition of DNA synthesis by an endogenous heat stable polypeptide. In Mechanisms of intestinal adaptation. 81-90. Robinson JWL (ed); Dowling RH (ed); Riecken E (ed). Kluwer Academic Pub (1982).
• Batt RM; Scott J. Response of the small intestinal mucosa to oral glucocorticoids. In Structure of the gut. 391-404. Polak JM (ed); Bloom (ed); Wright (ed); Daly (ed). Page Brothers, Norwich (1982).

Conferences

• Chambers J; Zhao J; Terracciano C; Bezzina C; Zhang W; Kaba R; Navaratnarajah M; Lotlikar A; et alSehmi J; Kooner M; Siedlecka U; Wass M; Dekker L; de Jong J; Sternberg M; McKenna W; Severs N; DeSilva R; Wilde A; Anand P; Yacoub M; Scott J; Elliot P; Wood J; Kooner J. Genetic Variation in SCN10a is Associated With Cardiac Conduction, Heart Block and Risk of Ventricular Fibrillation. 120:S579-S580. (3 Nov 2009).
• Elliot P; Chambers J; Sehmi J; Clarke R; Erdmann J; Braund P; Engert J; Ashby D; et alTzoulaki I; Peltonen L; Farrall M; Hamsten A; Froguel P; Waterworth D; Vollenweider P; Waeber G; Jarvelin MR; Scott J; Hall A; Schunkert H; Anand S; Collins R; Samani N; Watkins H; Kooner J. Does CRP Play a Causal Role in the Development of Coronary Heart Disease: Results of a Mendelian Randomisation Experiment Involving 128,935 People. 120:S467-S468. (3 Nov 2009).
• Waller-Evans HE; Fearnside J; Argoud K; Burt A; Wilder SP; Gut I; Scott J; Gauguier D. Identification and characterisation of candidate genes in diet-induced non-alcoholic fatty liver disease in inbred mice. 52:S259-S259. (Sep 2009).
• Elliott P; Chambers JC; Zhang W; Clarke R; Peden JF; Erdmann J; Braund P; Engert J; et alHopewell J; Coin L; Ashby D; McCarthy MI; Farrall M; Jarvelin MR; Scott J; Hall AS; Schunkert H; Anand SS; Collins R; Samani N; Watkins H; Kooner JS. GENETIC LOCI INFLUENCING C-REACTIVE PROTEIN LEVELS AND CORONARY HEART DISEASE RISK: RESULTS OF GENETIC ASSOCIATION AND MENDELIAN RANDOMISATION STUDY WITH META-ANALYSIS IN 80 614 PEOPLE. 95:A61-A61. (Jun 2009).
• Chambers JC; Zhang W; Sehmi J; Jain P; Scott J; Elliott P; Kooner JS. COMMON GENETIC VARIATION NEAR MTNR1B CONTRIBUTES TO RAISED PLASMA GLUCOSE AND INCREASED RISK OF TYPE-2 DIABETES AMONG INDIAN ASIANS. 95:A82-A82. (Jun 2009).
• Fearnside J; Waller-Evans H; Argoud K; Burt A; Wilder S; Gut I; Scott J; Gauguier D. IDENTIFICATION OF CANDIDATE GENES IN DIET INDUCED NON-ALCOHOLIC FATTY LIVER DISEASE IN INBRED MICE. 50:S258-S258. (2009).
• Chambers JC; Zhang W; Zabaneh D; Balding D; McCarthy MI; Scott J; Elliott P; Kooner JS. Does genetic variation in FTO account for the increased risk of obesity and type 2 diabetes in UK Indian Asians?. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A58-A59. (Jul 2008).
• Chambers JC; Elliott P; Scott J; Kooner JS. Genome-wide association study identifies mlxipl as a novel determinant of trigyceride levels in man. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A5-A5. (Jul 2008).
• Zhang W; Zabaneh D; Balding D; McCarthy MI; Elliott P; Scott J; Kooner JS; Chambers JC. Are Indian Asians genetically homogeneous? Implications for genetic association studies. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A65-A65. (Jul 2008).
• Chambers JC; Scott J; Hinds DA; Fraser KA; Warnes GR; Aguilar-Salinas C; Hyde C; Milos PM; et alThompson JF; Cox DR; Kooner JS. A genome-wide scan identifies novel and known DNA variants associated with component phenotypes of metabolic syndrome. 116:507-507. (16 Oct 2007).
• Zabaneh D; Chambers JC; Elliott P; Baliga R; Scott J; Balding DJ; Kooner JS. Estimating heritabilities and genetic correlations of insulin resistance and related metabolic traits in Indian families using a multivariate maximum likelihood approach. 16th Annual Meeting of the International-Genetic-Epidemiology-Society. 31:651-651. (Sep 2007).