Dr James Ware

James Ware is a Cardiology Specialist Registrar and NIHR Clinical Lecturer at the NIHR Royal Brompton Cardiovascular Biomedical Research Unit.

Dr Ware graduated from the University of Cambridge in 2000, and pursued general medical training in Cambridge, London and Geneva before appointment to specialist training in Cardiology in 2007.

He undertook doctoral research at the MRC Clinical Sciences Centre (2008-2011) in the laboratories of Prof Stuart Cook, Prof Tim Aitman and Prof Nicholas Peters, funded by a Fellowship from the Wellcome Trust.  He applied integrative genomics approaches to identify determinants of arrhythmia susceptibility in humans and modal systems.

Following a post-doctoral fellowship from the MRC, and a Leducq travelling fellowship in the Seidman laboratory in Harvard, Dr Ware was appointed an NIHR Clinical Lecturer in Cardiology in 2012. He is pursuing sub-specialty cardiology training in rhythm management and inherited cardiac conditions alongside ongoing research.

Research interests include:

Identifying genetic determinants of arrhythmia and sudden cardiac death

Understanding the molecular basis of inherited cardiac conditions

Applying "Next-Generation Sequencing” technologies for molecular diagnosis

Interpreting genetic variation for application in cardiovascular clinical genetics: particularly to discriminate rare benign genetic polymorphisms from pathogenic mutations