Dr Kevin G Murphy

Publications


Journals

  • Ramachandran R; Bech P; Murphy KG; Dhillo WS; Meeran KM; Chapman RS; Caplin M; Ghatei MA; et alBloom SR; Martin NM. (Jun 2012). Improved diagnostic accuracy for neuroendocrine neoplasms using two chromogranin A assays. Clin Endocrinol (Oxf). 76:831-836. DOI.
  • McGavigan AK; Murphy KG. (27 Mar 2012). Gut hormones: the future of obesity treatment?. Br J Clin Pharmacol. DOI.
  • Hill NE; Murphy KG; Singer M. (Apr 2012). Ghrelin, appetite and critical illness. Curr Opin Crit Care. 18:199-205. DOI.
  • Greenwood HC; Bloom SR; Murphy KG. (2011). Peptides and their potential role in the treatment of diabetes and obesity. Rev Diabet Stud. 8:355-368. DOI.
  • Kinsey-Jones JS; Murphy KG. (Dec 2011). Current models and strategies in the development of antiobesity drugs. Ann N Y Acad Sci. 1245:3-6. DOI.
  • Addison ML; Minnion JS; Shillito JC; Suzuki K; Tan TM; Field BC; Germain-Zito N; Becker-Pauly C; et alGhatei MA; Bloom SR; Murphy KG. (Dec 2011). A role for metalloendopeptidases in the breakdown of the gut hormone, PYY 3-36. Endocrinology. 152:4630-4640. DOI.
  • Jayasena CN; Nijher GM; Comninos AN; Abbara A; Januszewki A; Vaal ML; Sriskandarajah L; Murphy KG; et alFarzad Z; Ghatei MA; Bloom SR; Dhillo WS. (Dec 2011). The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans. J Clin Endocrinol Metab. 96:E1963-E1972. DOI.
  • Amin A; Dhillo WS; Murphy KG. (2011). The central effects of thyroid hormones on appetite. J Thyroid Res. 2011:306510. DOI.
  • Beale KE; Murphy KG; Harrison EK; Kerton AJ; Ghatei MA; Bloom SR; Smith KL. (Aug 2011). Accurate measurement of body weight and food intake in environmentally enriched male Wistar rats. Obesity (Silver Spring). 19:1715-1721. DOI.
  • McGowan BM; Minnion JS; Murphy KG; White NE; Roy D; Stanley SA; Dhillo WS; Gardiner JV; et alGhatei MA; Bloom SR. (Dec 2010). Central and peripheral administration of human relaxin-2 to adult male rats inhibits food intake. Diabetes Obes Metab. 12:1090-1096. DOI.
  • Nijher GM; Chaudhri OB; Ramachandran R; Murphy KG; Zac-Varghese SE; Fowler A; Chinthapalli K; Patterson M; et alThompson EL; Williamson C; Kumar S; Ghatei MA; Bloom SR; Dhillo WS. (Nov 2010). The effects of kisspeptin-54 on blood pressure in humans and plasma kisspeptin concentrations in hypertensive diseases of pregnancy. Br J Clin Pharmacol. 70:674-681. DOI.
  • Jayasena CN; Nijher GM; Abbara A; Murphy KG; Lim A; Patel D; Mehta A; Todd C; et alDonaldson M; Trew GH; Ghatei MA; Bloom SR; Dhillo WS. (Dec 2010). Twice-weekly administration of kisspeptin-54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea. Clin Pharmacol Ther. 88:840-847. DOI.
  • Boughton CK; Patterson M; Bewick GA; Tadross JA; Gardiner JV; Beale KEL; Chaudery F; Hunter G; et alBusbridge M; Leavy EM; Ghatei MA; Bloom SR; Murphy KG. (1 Oct 2010). Alarin stimulates food intake and gonadotrophin release in male rats. BRITISH JOURNAL OF PHARMACOLOGY. 161:601-613. DOI.
  • Liu YL; Ford HE; Druce MR; Minnion JS; Field BC; Shillito JC; Baxter J; Murphy KG; et alGhatei MA; Bloom SR. (Dec 2010). Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents. Int J Obes (Lond). 34:1715-1725. DOI.
  • Curtis AE; Murphy KG; Chaudhri OB; Ramachandran R; Young AM; Waxman J; Nijher GM; Bewick GA; et alGhatei MA; Bloom SR; Dhillo WS. (Jun 2010). Kisspeptin is released from human prostate cancer cell lines but plasma kisspeptin is not elevated in patients with prostate cancer. Oncol Rep. 23:1729-1734.
  • Thompson EL; Murphy KG. (Apr 2010). Modulation of the hypothalamic-pituitary-gonadal axis by selective ligands of the KISS1R. Curr Opin Investig Drugs. 11:432-439.
  • Nijher GM; Baxter JE; Chaudhri OB; Murphy KG; Ramachandran R; Fowler A; Chinthapalli K; Patterson M; et alJayasena CN; Williamson C; Kumar S; Ghatei MA; Bloom SR; Dhillo WS. (Jun 2010). Identification of the hormone kisspeptin in amniotic fluid. Clin Chem. 56:1029-1031. DOI.
  • Curtis AE; Cooke JH; Baxter JE; Parkinson JR; Bataveljic A; Ghatei MA; Bloom SR; Murphy KG. (Feb 2010). A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10. Am J Physiol Endocrinol Metab. 298:E296-E303. DOI.
  • Corander MP; Challis BG; Thompson EL; Jovanovic Z; Loraine Tung YC; Rimmington D; Huhtaniemi IT; Murphy KG; et alTopaloglu AK; Yeo GS; O'Rahilly S; Dhillo WS; Semple RK; Coll AP. (Mar 2010). The effects of neurokinin B upon gonadotrophin release in male rodents. J Neuroendocrinol. 22:181-187. DOI.
  • Curtis AE; Cooke JH; Baxter JE; Parkinson JR; Bataveljic A; Ghatei MA; Bloom SR; Murphy KG. (Feb 2010). A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10. Am J Physiol Endocrinol Metab. 298:E296-E303. DOI.
  • Gardiner JV; Bataveljic A; Patel NA; Bewick GA; Roy D; Campbell D; Greenwood HC; Murphy KG; et alHameed S; Jethwa PH; Ebling FJ; Vickers SP; Cheetham S; Ghatei MA; Bloom SR; Dhillo WS. (Feb 2010). Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake. Diabetes. 59:397-406. DOI.
  • Jayasena CN; Nijher GM; Chaudhri OB; Murphy KG; Ranger A; Lim A; Patel D; Mehta A; et alTodd C; Ramachandran R; Salem V; Stamp GW; Donaldson M; Ghatei MA; Bloom SR; Dhillo WS. (Nov 2009). Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis. J Clin Endocrinol Metab. 94:4315-4323. DOI.
  • Ashby DR; Gale DP; Busbridge M; Murphy KG; Duncan ND; Cairns TD; Taube DH; Bloom SR; et alTam FW; Chapman R; Maxwell PH; Choi P. (Mar 2010). Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin. Haematologica. 95:505-508. DOI.
  • Patterson M; Murphy KG; Patel SR; Patel NA; Greenwood HC; Cooke JH; Campbell D; Bewick GA; et alGhatei MA; Bloom SR. (1 Aug 2009). Hypothalamic Injection of Oxyntomodulin Suppresses Circulating Ghrelin-Like Immunoreactivity. ENDOCRINOLOGY. 150:3513-3520. Author weblink DOI.
  • Semjonous NM; Smith KL; Parkinson JR; Gunner DJ; Liu YL; Murphy KG; Ghatei MA; Bloom SR; et alSmall CJ. (Jul 2009). Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance. Int J Obes (Lond). 33:775-785. DOI.
  • Ashby DR; Ford HE; Wynne KJ; Wren AM; Murphy KG; Busbridge M; Brown EA; Taube DH; et alGhatei MA; Tam FW; Bloom SR; Choi P. (Jul 2009). Sustained appetite improvement in malnourished dialysis patients by daily ghrelin treatment. Kidney Int. 76:199-206. DOI.
  • Cooke JH; Patterson M; Patel SR; Smith KL; Ghatei MA; Bloom SR; Murphy KG. (1 Jun 2009). Peripheral and Central Administration of Xenin and Neurotensin Suppress Food Intake in Rodents. OBESITY. 17:1135-1143. Author weblink DOI.
  • Ashby DR; Gale DP; Busbridge M; Murphy KG; Duncan ND; Cairns TD; Taube DH; Bloom SR; et alTam FWK; Chapman RS; Maxwell PH; Choi P. (1 May 2009). Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease. KIDNEY INTERNATIONAL. 75:976-981. Author weblink DOI.
  • Druce MR; Minnion JS; Field BCT; Patel SR; Shillito JC; Tilby M; Beale KEL; Murphy KG; et alGhatei MA; Bloom SR. (1 Apr 2009). Investigation of Structure-Activity Relationships of Oxyntomodulin (Oxm) Using Oxm Analogs. ENDOCRINOLOGY. 150:1712-1721. Author weblink DOI.
  • Dhillo WS; Bewick GA; White NE; Gardiner JV; Thompson EL; Bataveljic A; Murphy KG; Roy D; et alPatel NA; Scutt JN; Armstrong A; Ghatei MA; Bloom SR. (1 Mar 2009). The thyroid hormone derivative 3-iodothyronamine increases food intake in rodents. DIABETES OBESITY & METABOLISM. 11:251-260. Author weblink DOI.
  • Thompson EL; Amber V; Stamp GW; Patterson M; Curtis AE; Cooke JH; Appleby GF; Dhillo WS; et alGhatei MA; Bloom SR; Murphy KG. (Feb 2009). Kisspeptin-54 at high doses acutely induces testicular degeneration in adult male rats via central mechanisms. Br J Pharmacol. 156:609-625. DOI.
  • Green DA; Golding JF; Aulakh M; Faldon MC; Murphy KG; Bronstein AM; Gresty MA. (Dec 2008). Adaptation of ventilation to 'buffeting' in vehicles. Clin Auton Res. 18:351-351. Publisher weblink DOI.
  • Green DA; Golding JF; Mandip A; Faldon MC; Murphy KG; Bronstein AM; Gresty MA. (1 Dec 2008). Adaptation of ventilation to 'buffeting' in vehicles. CLINICAL AUTONOMIC RESEARCH. 18:346-U1. Author weblink DOI.
  • Liu Y-L; Semjonous NM; Murphy KG; Ghatei MA; Bloom SR. (1 Nov 2008). The effects of pancreatic polypeptide on locomotor activity and food intake in mice. INTERNATIONAL JOURNAL OF OBESITY. 32:1712-1715. Author weblink DOI.
  • Smith KL; Gardiner JV; Ward HL; Kong WM; Murphy KG; Martin NM; Ghatei MA; Bloom SR. (1 Oct 2008). Overexpression of CART in the PVN increases food intake and weight gain in rats. OBESITY. 16:2239-2244. Author weblink DOI.
  • Patel SR; Murphy KG; Thompson EL; Patterson M; Curtis AE; Ghatei MA; Bloom SR. (1 Sep 2008). Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats. ENDOCRINOLOGY. 149:4747-4754. Author weblink DOI.
  • McGowan BM; Stanley SA; Donovan J; Thompson EL; Patterson M; Semjonous NM; Gardiner JV; Murphy KG; et alGhatei MA; Bloom SR. (1 Aug 2008). Relaxin-3 stimulates the hypothalamic-pituitary-gonadal axis. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 295:E278-E286. Author weblink DOI.
  • Bech P; Winstanley V; Murphy KG; Sam AH; Meeran K; Ghatei MA; Bloom SR. (Apr 2008). Elevated cocaine- and amphetamine-regulated transcript immunoreactivity in the circulation of patients with neuroendocrine malignancy. J Clin Endocrinol Metab. 93:1246-1253. DOI.
  • Ramachandran R; Patterson M; Murphy KG; Dhillo WS; Patel S; Kazarian A; Ghatei MA; Bloom SR. (1 Mar 2008). Preanalytical factors affecting RIA measurement of plasma kisspeptin. CLINICAL CHEMISTRY. 54:615-617. Author weblink DOI.
  • Chaudhri OB; Salem V; Murphy KG; Bloom SR. (1 Jan 2008). Gastrointestinal satiety signals. ANNUAL REVIEW OF PHYSIOLOGY. 70:239-255. Author weblink DOI.
  • le Roux CW; Borg CM; Murphy KG; Vincent RP; Ghatei MA; Bloom SR. (Jan 2008). Supraphysiological doses of intravenous PYY3-36 cause nausea, but no additional reduction in food intake. Ann Clin Biochem. 45:93-95. DOI.
  • Dhillo WS; Chaudhri OB; Thompson EL; Murphy KG; Patterson M; Ramachandran R; Nijher GK; Amber V; et alKokkinos A; Donaldson M; Ghatei MA; Bloom SR. (1 Oct 2007). Kisspeptin-54 stimulates gonadotropin release most potently during the Preovulatory phase of the menstrual cycle in women. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 92:3958-3966. Author weblink DOI.
  • Dhillo WS; Murphy KG; Bloom SR. (Mar 2007). The neuroendocrine physiology of kisspeptin in the human. Rev Endocr Metab Disord. 8:41-46. DOI.
  • Murphy KG; Bloom SR. (16 Jan 2007). Nonpeptidic glucagon-like peptide 1 receptor agonists: a magic bullet for diabetes?. Proc Natl Acad Sci U S A. 104:689-690. DOI.
  • Murphy KG; Bloom SR. (14 Dec 2006). Gut hormones and the regulation of energy homeostasis. Nature. 444:854-859. DOI.
  • Murphy KG; Dhillo WS; Bloom SR. (1 Dec 2006). Gut peptides in the regulation of food intake and energy homeostasis. ENDOCRINE REVIEWS. 27:719-727. Author weblink DOI.
  • Dhillo WS; Savage P; Murphy KG; Chaudhri OB; Patterson M; Nijher GM; Foggo VM; Dancey GS; et alMitchell H; Seckl MJ; Ghatei MA; Bloom SR. (Nov 2006). Plasma kisspeptin is raised in patients with gestational trophoblastic neoplasia and falls during treatment. Am J Physiol Endocrinol Metab. 291:E878-E884. DOI.
  • Thompson EL; Murphy KG; Patterson M; Bewick GA; Stamp GW; Curtis AE; Cooke JH; Jethwa PH; et alTodd JF; Ghatei MA; Bloom SR. (Nov 2006). Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats. Am J Physiol Endocrinol Metab. 291:E1074-E1082. DOI.
  • Patterson M; Murphy KG; Thompson EL; Smith KL; Meeran K; Ghatei MA; Bloom SR. (Oct 2006). Microinjection of galanin-like peptide into the medial preoptic area stimulates food intake in adult male rats. J Neuroendocrinol. 18:742-747. DOI.
  • Dhillo WS; Murphy KG; Bloom S. (Jul 2006). Endocrinology: the next 60 years. J Endocrinol. 190:7-10. DOI.
  • Jethwa PH; Smith KL; Small CJ; Abbott CR; Darch SJ; Murphy KG; Seth A; Semjonous NM; et alPatel SR; Todd JF; Ghatei MA; Bloom SR. (Jun 2006). Neuromedin U partially mediates leptin-induced hypothalamo-pituitary adrenal (HPA) stimulation and has a physiological role in the regulation of the HPA axis in the rat. Endocrinology. 147:2886-2892. DOI Open Access copy.
  • Patterson M; Murphy KG; Thompson EL; Patel S; Ghatei MA; Bloom SR. (May 2006). Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats. J Neuroendocrinol. 18:349-354. DOI.
  • Patel AD; Stanley SA; Murphy KG; Frost GS; Gardiner JV; Kent AS; White NE; Ghatei MA; et alBloom SR. (15 Mar 2006). Ghrelin stimulates insulin-induced glucose uptake in adipocytes. Regul Pept. 134:17-22. DOI.
  • Murphy KG; Bloom SR. (Jan 2006). Are all fats created equal?. Nat Med. 12:32-33. DOI.
  • Mahmoodi M; Gardiner JV; Karam GRA; Khaksari M; Murphy KG; Ghatei MA; Bloom SR. (15 Dec 2005). Implantation of fibre encapsulated RIN 1056a cells transfected with NPY cDNA into the lateral ventricle of rats alters body weight. REGULATORY PEPTIDES. 132:80-84. Author weblink DOI.
  • Dhillo WS; Chaudhri OB; Patterson M; Thompson EL; Murphy KG; Badman MK; McGowan BM; Amber V; et alPatel S; Ghatei MA; Bloom SR. (Dec 2005). Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. J Clin Endocrinol Metab. 90:6609-6615. DOI.
  • Murphy KG; Bloom SR. (Oct 2005). Peripheral influences on central melanocortin neurons. Peptides. 26:1744-1752. DOI.
  • Jethwa PH; Small CJ; Smith KL; Seth A; Darch SJ; Abbott CR; Murphy KG; Todd JF; et alGhatei MA; Bloom SR. (Aug 2005). Neuromedin U has a physiological role in the regulation of food intake and partially mediates the effects of leptin. Am J Physiol Endocrinol Metab. 289:E301-E305. DOI.
  • Bewick GA; Dhillo WS; Darch SJ; Murphy KG; Gardiner JV; Jethwa PH; Kong WM; Ghatei MA; et alBloom SR. (Aug 2005). Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release. Endocrinology. 146:3526-3534. DOI.
  • McGowan BM; Stanley SA; Smith KL; White NE; Connolly MM; Thompson EL; Gardiner JV; Murphy KG; et alGhatei MA; Bloom SR. (Aug 2005). Central relaxin-3 administration causes hyperphagia in male Wistar rats. Endocrinology. 146:3295-3300. DOI Open Access copy.
  • Wynne K; Park AJ; Small CJ; Patterson M; Ellis SM; Murphy KG; Wren AM; Frost GS; et alMeeran K; Ghatei MA; Bloom SR. (Aug 2005). Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial. Diabetes. 54:2390-2395.
  • Murphy KG. (Aug 2005). Kisspeptins: regulators of metastasis and the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol. 17:519-525. DOI.
  • Murphy KG. (Jul 2005). Dissecting the role of cocaine- and amphetamine-regulated transcript (CART) in the control of appetite. Brief Funct Genomic Proteomic. 4:95-111.
  • Patterson M; Murphy KG; le Roux CW; Ghatei MA; Bloom SR. (Apr 2005). Characterization of ghrelin-like immunoreactivity in human plasma. J Clin Endocrinol Metab. 90:2205-2211. DOI.
  • Forbes S; Moonan M; Robinson S; Anyaoku V; Patterson M; Murphy KG; Ghatei MA; Bloom SR; et alJohnston DG. (Jan 2005). Impaired circulating glucagon-like peptide-1 response to oral glucose in women with previous gestational diabetes. Clin Endocrinol (Oxf). 62:51-55. DOI.
  • Gardiner JV; Kong WM; Ward H; Murphy KG; Dhillo WS; Bloom SR. (25 Feb 2005). AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake. Biochem Biophys Res Commun. 327:1088-1093. DOI.
  • Thompson EL; Murphy KG; Todd JF; Martin NM; Small CJ; Ghatei MA; Bloom SR. (8 Oct 2004). Chronic administration of NMU into the paraventricular nucleus stimulates the HPA axis but does not influence food intake or body weight. Biochem Biophys Res Commun. 323:65-71. DOI.
  • Thompson EL; Patterson M; Murphy KG; Smith KL; Dhillo WS; Todd JF; Ghatei MA; Bloom SR. (Oct 2004). Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol. 16:850-858. DOI Open Access copy.
  • Stanley SA; Murphy KG; Bewick GA; Kong WM; Opacka-Juffry J; Gardiner JV; Ghatei M; Small CJ; et alBloom SR. (Sep 2004). Regulation of rat pituitary cocaine- and amphetamine-regulated transcript (CART) by CRH and glucocorticoids. Am J Physiol Endocrinol Metab. 287:E583-E590. DOI.
  • Murphy KG; Bloom SR. (Sep 2004). Gut hormones in the control of appetite. Exp Physiol. 89:507-516. DOI.
  • Abbott CR; Kennedy AR; Wren AM; Rossi M; Murphy KG; Seal LJ; Todd JF; Ghatei MA; et alSmall CJ; Bloom SR. (Sep 2003). Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone. Endocrinology. 144:3943-3949.
  • Kong WM; Stanley S; Gardiner J; Abbott C; Murphy K; Seth A; Connoley I; Ghatei M; et alStephens D; Bloom S. (Sep 2003). A role for arcuate cocaine and amphetamine-regulated transcript in hyperphagia, thermogenesis, and cold adaptation. FASEB J. 17:1688-1690. DOI.
  • Dhillo WS; Small CJ; Jethwa PH; Russell SH; Gardiner JV; Bewick GA; Seth A; Murphy KG; et alGhatei MA; Bloom SR. (Apr 2003). Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis. Endocrinology. 144:1420-1425.
  • Seth A; Stanley S; Dhillo W; Murphy K; Ghatei M; Bloom S. (Feb 2003). Effects of galanin-like peptide on food intake and the hypothalamo-pituitary-thyroid axis. Neuroendocrinology. 77:125-131. DOI.
  • Ward H; Gardiner J; Kong WM; Murphy K; Bloom S. (Feb 2003). Distribution of fluorescence following injection of recombinant adeno-associated virus encoding green fluorescent protein into the paraventricular nucleus. Neuroendocrinology. 77:100-104. DOI.
  • Wren AM; Small CJ; Abbott CR; Jethwa PH; Kennedy AR; Murphy KG; Stanley SA; Zollner AN; et alGhatei MA; Bloom SR. (Nov 2002). Hypothalamic actions of neuromedin U. Endocrinology. 143:4227-4234. Open Access copy.
  • Dhillo WS; Small CJ; Stanley SA; Jethwa PH; Seal LJ; Murphy KG; Ghatei MA; Bloom SR. (Sep 2002). Hypothalamic interactions between neuropeptide Y, agouti-related protein, cocaine- and amphetamine-regulated transcript and alpha-melanocyte-stimulating hormone in vitro in male rats. J Neuroendocrinol. 14:725-730.
  • Dhillo WS; Small CJ; Seal LJ; Kim MS; Stanley SA; Murphy KG; Ghatei MA; Bloom SR. (Apr 2002). The hypothalamic melanocortin system stimulates the hypothalamo-pituitary-adrenal axis in vitro and in vivo in male rats. Neuroendocrinology. 75:209-216.
  • Taheri S; Murphy K; Cohen M; Sujkovic E; Kennedy A; Dhillo W; Dakin C; Sajedi A; et alGhatei M; Bloom S. (15 Mar 2002). The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats. Biochem Biophys Res Commun. 291:1208-1212. DOI.
  • Wren AM; Seal LJ; Cohen MA; Brynes AE; Frost GS; Murphy KG; Dhillo WS; Ghatei MA; et alBloom SR. (Dec 2001). Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab. 86:5992. Open Access copy.
  • Russell SH; Small CJ; Kennedy AR; Stanley SA; Seth A; Murphy KG; Taheri S; Ghatei MA; et alBloom SR. (Dec 2001). Orexin A interactions in the hypothalamo-pituitary gonadal axis. Endocrinology. 142:5294-5302.
  • Wren AM; Seal LJ; Cohen MA; Brynes AE; Frost GS; Murphy KG; Dhillo WS; Ghatei MA; et alBloom SR. (1 Dec 2001). Ghrelin enhances appetite and increases food intake in humans. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 86:5992-5995. Author weblink DOI.
  • Ward HL; Small CJ; Murphy KG; Kennedy AR; Ghatei MA; Bloom SR. (Aug 2001). The actions of tuberoinfundibular peptide on the hypothalamo-pituitary axes. Endocrinology. 142:3451-3456.
  • Abbott CR; Rossi M; Wren AM; Murphy KG; Kennedy AR; Stanley SA; Zollner AN; Morgan DG; et alMorgan I; Ghatei MA; Small CJ; Bloom SR. (Aug 2001). Evidence of an orexigenic role for cocaine- and amphetamine-regulated transcript after administration into discrete hypothalamic nuclei. Endocrinology. 142:3457-3463.
  • Sunter D; Morgan I; Edwards CM; Dakin CL; Murphy KG; Gardiner J; Taheri S; Rayes E; et alBloom SR. (13 Jul 2001). Orexins: effects on behavior and localisation of orexin receptor 2 messenger ribonucleic acid in the rat brainstem. Brain Res. 907:27-34.
  • Taheri S; Gardiner J; Hafizi S; Murphy K; Dakin C; Seal L; Small C; Ghatei M; et alBloom S. (5 Mar 2001). Orexin A immunoreactivity and preproorexin mRNA in the brain of Zucker and WKY rats. Neuroreport. 12:459-464.
  • Stanley SA; Small CJ; Murphy KG; Rayes E; Abbott CR; Seal LJ; Morgan DG; Sunter D; et alDakin CL; Kim MS; Hunter R; Kuhar M; Ghatei MA; Bloom SR. (2 Mar 2001). Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats. Brain Res. 893:186-194.
  • Small CJ; Kim MS; Stanley SA; Mitchell JR; Murphy K; Morgan DG; Ghatei MA; Bloom SR. (Feb 2001). Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals. Diabetes. 50:248-254.
  • Russell SH; Kim MS; Small CJ; Abbott CR; Morgan DG; Taheri S; Murphy KG; Todd JF; et alGhatei MA; Bloom SR. (Dec 2000). Central administration of orexin A suppresses basal and domperidone stimulated plasma prolactin. J Neuroendocrinol. 12:1213-1218.
  • Wren AM; Small CJ; Ward HL; Murphy KG; Dakin CL; Taheri S; Kennedy AR; Roberts GH; et alMorgan DG; Ghatei MA; Bloom SR. (Nov 2000). The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology. 141:4325-4328.
  • Murphy KG; Abbott CR; Mahmoudi M; Hunter R; Gardiner JV; Rossi M; Stanley SA; Ghatei MA; et alKuhar MJ; Bloom SR. (Sep 2000). Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues. J Endocrinol. 166:659-668.
  • Edwards CM; Abbott CR; Sunter D; Kim M; Dakin CL; Murphy KG; Abusnana S; Taheri S; et alRossi M; Bloom SR. (2 Jun 2000). Cocaine- and amphetamine-regulated transcript, glucagon-like peptide-1 and corticotrophin releasing factor inhibit feeding via agouti-related protein independent pathways in the rat. Brain Res. 866:128-134.
  • Satoh F; Smith DM; Gardiner JV; Mahmoodi M; Murphy KG; Ghatei MA; Bloom SR. (Apr 2000). Characterization and distribution of prolactin releasing peptide (PrRP) binding sites in the rat--evidence for a novel binding site subtype in cardiac and skeletal muscle. Br J Pharmacol. 129:1787-1793. DOI.
  • Edwards CM; Abusnana S; Sunter D; Murphy KG; Ghatei MA; Bloom SR. (Mar 1999). The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin. J Endocrinol. 160:R7-12.

Conferences

  • Ramachandran R; Bech P; Murphy KG; Dhillo WS; Marelli L; Ghatei MA; Bloom SR; Caplin M; et alMartin NM. Plasma Somatostatin: Gastrin Ratio Improves the Diagnosis of Gastrinoma. 8th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocine Tumor Disease, 9 Mar 2011 - 11 Mar 2011. 94:9-9. KARGER (1 Jan 2011).
  • Ramachandran R; Bech P; Murphy KG; Dhillo WS; Marelli L; Ghatei MA; Bloom SR; Caplin M; et alMartin NM. PLASMA GASTRIN: SOMATOSTATIN RATIO IS DECREASED IN GASTRINOMAS. Annual Meeting on British-Society-of-Gasenterology, 14 Mar 2011 - 17 Mar 2011. 60:A117-A117. B M J PUBLISHING GROUP (1 Apr 2011). DOI.
  • Ramachandran R; Bech P; Murphy KG; Dhillo WS; Meeran KM; Chapman RC; Caplin M; Ghatei MA; et alBloom SR; Martin NM. Chromogranin A assays: Comparison of diagnostic accuracy. 18th International Symposium on Regulatory Peptides, 5 Sep 2010 - 8 Sep 2010. 164:12-12. ELSEVIER SCIENCE BV (9 Sep 2010). DOI.
  • Jayasena CN; Nijher GMK; Abbara A; Murphy KG; Lim A; Patel DA; Mehta A; Todd C; et alDonaldson M; Trew G; Ghatei MA; Bloom SR; Dhillo WS. Twice-Weekly Administration of Kisspeptin-54 for Eight Weeks Stimulates Reproductive Hormone Release in Women with Hypothalamic Amenorrhea. 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), 19 Jun 2010 - 22 Jun 2010. 31:S2527-S2527. ENDOCRINE SOC (1 Jun 2010). Author weblink.
  • Addison ML; Minnion JS; Shillito JC; Tan T; Murphy KG; Ghatei MG; Bloom SR. Investigating the Metabolic Clearance and Degradation of the Anorexigenic Gut Hormone PYY3-36 as a Tool To Design Long-Acting Analogues of PYY3-36 for the Treatment of Obesity. 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), 19 Jun 2010 - 22 Jun 2010. 31. ENDOCRINE SOC (1 Jun 2010). Author weblink.
  • Hostomska K; Salem V; Field BCT; Murphy KG; Ghatei MA; Bloom SR. Resistance to the Anorectic Effect of PYY3-36 during Continuous Infusion Is Independent from the Stimulation of Appetite Resulting from Weight Loss. 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), 19 Jun 2010 - 22 Jun 2010. 31. ENDOCRINE SOC (1 Jun 2010). Author weblink.
  • Boughton CK; Patterson M; Tadross JA; Bewick GA; Gardiner JV; Ghatei MA; Bloom SR; Murphy KG. The Novel Neuropeptide Alarin Stimulates Food Intake and the Reproductive Axis in Male Rats. 92nd Meeting and Expo of the Endocrine Society (ENDO 2010), 19 Jun 2010 - 22 Jun 2010. 31. ENDOCRINE SOC (1 Jun 2010). Author weblink.
  • Murphy KG; Thompson EL; Patterson M; Bewick GA; Jethwa PH; Stamp GWH; Todd JF; Ghatei MA; et alBloom SR. Continuous subcutaneous administration of kisspeptin-54 causes testicular degeneration in rats. 6th International Congress of Neuroendocrinology, 19 Jun 2006 - 22 Jun 2006. 27:77-77. ACADEMIC PRESS INC ELSEVIER SCIENCE (1 May 2006). Author weblink DOI.
Share this on Delicious
Tweet this
Digg this
Stumble this
Share this on Facebook