Dr Keith G Gould

Publications


Journals

  • Köhler K; Xiong S; Brzostek J; Mehrabi M; Eissmann P; Harrison A; Cordoba SP; Oddos S; et alMiloserdov V; Gould K; Burroughs NJ; van der Merwe PA; Davis DM. (2010). Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells. PLoS One. 5:e15374. DOI.
  • Kotsiou E; Brzostek J; Gould KG. (1 Aug 2011). Properties and applications of single-chain major histocompatibility complex class I molecules. Antioxid Redox Signal. 15:645-655. DOI.
  • Kotsiou E; Brzostek J; Lenart I; Antoniou AN; Dyson J; Gould KG. (1 Aug 2011). Dimerization of soluble disulfide trap single-chain major histocompatibility complex class I molecules dependent on peptide binding affinity. Antioxid Redox Signal. 15:635-644. DOI.
  • Hansen TH; Connolly JM; Gould KG; Fremont DH. (Oct 2010). Basic and translational applications of engineered MHC class I proteins. Trends Immunol. 31:363-369. DOI.
  • Brzostek J; Chai JG; Gebhardt F; Busch DH; Zhao R; van der Merwe PA; Gould KG. (Jul 2010). Ligand dimensions are important in controlling NK-cell responses. Eur J Immunol. 40:2050-2059. DOI.
  • Palankar R; Skirtach AG; Kreft O; Bédard M; Garstka M; Gould K; Möhwald H; Sukhorukov GB; et alWinterhalter M; Springer S. (23 Sep 2009). Intracellular transport: Small 19/2009. Small. 5. DOI.
  • Palankar R; Skirtach AG; Kreft O; Bédard M; Garstka M; Gould K; Möhwald H; Sukhorukov GB; et alWinterhalter M; Springer S. (Oct 2009). Controlled intracellular release of peptides from microcapsules enhances antigen presentation on MHC class I molecules. Small. 5:2168-2176. DOI.
  • Choudhuri K; Parker M; Milicic A; Cole DK; Shaw MK; Sewell AK; Stewart-Jones G; Dong T; et alGould KG; van der Merwe PA. (18 Sep 2009). Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activation. J Biol Chem. 284:26096-26105. DOI.
  • Palmowski MJ; Parker M; Choudhuri K; Chiu C; Callan MFC; van der Merwe PA; Cerundolo V; Gould KG. (15 Apr 2009). A Single-Chain H-2D(b) Molecule Presenting an Influenza Virus Nucleoprotein Epitope Shows Enhanced Ability at Stimulating CD8(+) T Cell Responses In Vivo. JOURNAL OF IMMUNOLOGY. 182:4565-4571. Author weblink DOI.
  • Powis SJ; Nesbeth D; Lenart I; Fussell H; Lamb T; Gould K; Antoniou AN. (1 Jan 2009). Rapid acidification and alkylation: redox analysis of the MHC class I pathway. J Immunol Methods. 340:81-85. DOI.
  • Fussell H; Nesbeth D; Lenart I; Campbell EC; Lynch S; Santos S; Gould K; Powis SJ; et alAntoniou AN. (Nov 2008). Novel detection of in vivo HLA-B27 conformations correlates with ankylosing spondylitis association. Arthritis Rheum. 58:3419-3424. DOI.
  • Zhang Y; Li S; Shan M; Pan X; Zhuang K; He L; Gould K; Tien P. (1 May 2007). Hepatitis B virus core antigen epitopes presented by HLA-A2 single-chain trimers induce functional epitope-specific CD8(+) T-cell responses in HLA-A2.1/Kb transgenic mice. IMMUNOLOGY. 121:105-112. Author weblink DOI.
  • Choudhuri K; Wiseman D; Brown MH; Gould K; van der Merwe PA. (28 Jul 2005). T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand. Nature. 436:578-582. DOI.
  • Tourdot S; Nejmeddine M; Powis SJ; Gould KG. (15 Jan 2005). Different MHC class I heavy chains compete with each other for folding independently of beta 2-microglobulin and peptide. J Immunol. 174:925-933.
  • Goon PK; Biancardi A; Fast N; Igakura T; Hanon E; Mosley AJ; Asquith B; Gould KG; et alMarshall S; Taylor GP; Bangham CR. (15 Jun 2004). Human T cell lymphotropic virus (HTLV) type-1-specific CD8+ T cells: frequency and immunodominance hierarchy. J Infect Dis. 189:2294-2298. DOI.
  • Goon PK; Igakura T; Hanon E; Mosley AJ; Asquith B; Gould KG; Taylor GP; Weber JN; et alBangham CR. (Sep 2003). High circulating frequencies of tumor necrosis factor alpha- and interleukin-2-secreting human T-lymphotropic virus type 1 (HTLV-1)-specific CD4+ T cells in patients with HTLV-1-associated neurological disease. J Virol. 77:9716-9722.
  • Tourdot S; Gould KG. (15 Nov 2002). Competition between MHC class I alleles for cell surface expression alters CTL responses to influenza A virus. J Immunol. 169:5615-5621.
  • Lomas M; Hanon E; Tanaka Y; Bangham CR; Gould KG. (Mar 2002). Presentation of a new H-2D(k)-restricted epitope in the Tax protein of human T-lymphotropic virus type I is enhanced by the proteasome inhibitor lactacystin. J Gen Virol. 83:641-650.
  • Tourdot S; Herath S; Gould KG. (Jul 2001). Characterization of a new H-2D(k)-restricted epitope prominent in primary influenza A virus infection. J Gen Virol. 82:1749-1755.
  • Potter P; Tourdot S; Blanchard T; Smith GL; Gould KG. (May 2001). Differential processing and presentation of the H-2D(b)-restricted epitope from two different strains of influenza virus nucleoprotein. J Gen Virol. 82:1069-1074.
  • Neyrolles O; Gould K; Gares MP; Brett S; Janssen R; O'Gaora P; Herrmann JL; Prévost MC; et alPerret E; Thole JE; Young D. (1 Jan 2001). Lipoprotein access to MHC class I presentation during infection of murine macrophages with live mycobacteria. J Immunol. 166:447-457.
  • Gould, K G; Bangham, C R. (1998). Virus variation, escape from cytotoxic T lymphocytes and human retroviral persistence. Semin Cell Dev Biol. 9:321-328.
  • Cerundolo, V; Benham, A; Braud, V; Mukherjee, S; Gould, K; Macino, B; Neefjes, J; Townsend, A. (1997). The proteasome-specific inhibitor lactacystin blocks presentation of cytotoxic T lymphocyte epitopes in human and murine cells. European Journal of Immunology. 27:336-341.

Conferences

  • Antoniou AN; Guiliano D; Lenart I; North H; Nesbeth D; Gould K; Powis S. Does the build up of molecular garbage lead to inflammatory arthritis?. Annual Congress of the British-Society-for-Immunology, 5 Dec 2011 - 8 Dec 2011. 135:159-159. WILEY-BLACKWELL (1 Dec 2011). Author weblink.
  • Guiliano D; Lenart I; Fussell H; Nesbeth D; Tsao E; Cameron A; Gould K; Powis S; et alAntoniou A. Calnexin modulates HLA-B27 homodimerisation. Annual Congress of the British-Society-for-Immunology, 6 Dec 2010 - 10 Dec 2010. 131:109-109. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2010). Author weblink.
  • Lenart I; Nesbeth D; Gould K; Antoniou A. HLA-B27 homodimerisation: consequences for inflammatory arthritis?. Annual Congress of the British-Society-for-Immunology, 6 Dec 2010 - 10 Dec 2010. 131:108-108. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2010). Author weblink.
  • Guiliano DB; Nesbeth D; Gould K; Noursadeghi M; Antoniou AN. The folding status of HLA-B27 influences the outcome S. typhimurium infection. Annual Congress of the British-Society-for-Immunology, 6 Dec 2010 - 10 Dec 2010. 131:107-107. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2010). Author weblink.
  • Kotsiou E; Silk J; Cerundolo V; Dyson PJ; Gould KG. Application of HLA class I single chain trimers for leukaemia immunotherapy. Annual Congress of the British-Society-of-Immunology, 17 Nov 2008 - 21 Nov 2008. 125:52-52. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2008). Author weblink.
  • Brzostek J; van der Merwe PA; Gould KG. The importance of ligand dimensions in natural killer cell inhibition. Annual Congress of the British-Society-of-Immunology, 17 Nov 2008 - 21 Nov 2008. 125:15-15. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2008). Author weblink.
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