Dr Louise J Fleming

Dr Louise Fleming is a Clinical Senior Lecturer in Respiratory Paediatrics at the National Heart and Lung Institute with a research interest in children with problematic asthma.

She completed her undergraduate degree in medicine at the University of Manchester before moving to London for postgraduate training in Paediatrics. This included an 18 month VSO/RCPCH Fellowship in The Gambia.

Dr Fleming undertook postgraduate research at NHLI and the Royal Brompton Hospital, funded by the British Lung Foundation, under the supervision of Professor Andrew Bush and Dr Nicola Wilson. She carried out a randomised controlled trial investigating the use of inflammatory markers to guide management in children with severe asthma leading to the award of an MD(Res) degree. During this time she also developed the difficult asthma protocol at the Royal Brompton Hospital and the National Registry for children with difficult asthma. She subsequently undertook further research investigating the use of non-invasive measures of inflammation in children with asthma.

In 2008 she joined the U-BIOPRED (unbiased biomarkers for the prediction of respiratory disease outcomes) consortium working on protocol development. This is an IMI funded European wide study recruiting adults and children with severe asthma.

Dr Fleming’s research interests include distinguishing difficult from severe therapy resistant asthma, phenotyping severe asthma and the use of biomarkers in asthma and pre school wheeze.