Dr Linda Troeberg

Publications


Journals

  • Selvais C; D'Auria L; Tyteca D; Perrot G; Lemoine P; Troeberg L; Dedieu S; Noel A; et alNagase H; Henriet P; Courtoy PJ; Marbaix E; Emonard H. (1 Aug 2011). Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function. FASEB JOURNAL. 25:2770-2781. DOI.
  • Durigova M; Troeberg L; Nagase H; Roughley PJ; Mort JS. (1 Jan 2011). INVOLVEMENT OF ADAMTS5 AND HYALURONIDASE IN AGGRECAN DEGRADATION AND RELEASE FROM OSM-STIMULATED CARTILAGE. EUROPEAN CELLS & MATERIALS. 21:31-45.
  • Jain A; Miller M-C; Troeberg L; Itoh Y; Brennan F; Nanchahal J. (1 Sep 2009). Invasive Potential of Human Rheumatoid Tenosynovial Cells Is in Part MT1-MMP Dependent. JOURNAL OF HAND SURGERY-AMERICAN VOLUME. 34A:1282-1290. Author weblink DOI.
  • Troeberg L; Fushimi K; Scilabra SD; Nakamura H; Dive V; Thøgersen IB; Enghild JJ; Nagase H. (Oct 2009). The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3. Matrix Biol. 28:463-469. DOI.
  • Miller MC; Manning HB; Jain A; Troeberg L; Dudhia J; Essex D; Sandison A; Seiki M; et alNanchahal J; Nagase H; Itoh Y. (Mar 2009). Membrane type 1 matrix metalloproteinase is a crucial promoter of synovial invasion in human rheumatoid arthritis. Arthritis Rheum. 60:686-697. DOI.
  • Troeberg L; Fushimi K; Khokha R; Emonard H; Ghosh P; Nagase H. (1 Oct 2008). Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases. FASEB JOURNAL. 22:3515-3524. Author weblink DOI.
  • Troeberg L; Nagase H. (Nov 2004). Zymography of metalloproteinases. Curr Protoc Protein Sci. Chapter 21:Unit-21.15. DOI.
  • Troeberg L; Nagase H. (Nov 2004). Monitoring metalloproteinase activity using synthetic fluorogenic substrates. Curr Protoc Protein Sci. Chapter 21:Unit-21.16. DOI.
  • Fushimi K; Troeberg L; Nakamura H; Lim NH; Nagase H. (14 Mar 2008). Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity. JOURNAL OF BIOLOGICAL CHEMISTRY. 283:6706-6716. Author weblink DOI.
  • Emonard H; Bellon G; Troeberg L; Berton A; Robinet A; Henriet P; Marbaix E; Kirkegaard K; et alPatthy L; Eeckhout Y; Nagase H; Hornebeck W; Courtoy PJ. (24 Dec 2004). Low density lipoprotein receptor-related protein mediates endocytic clearance of Pro-MMP-2 center dot TIMP-2 complex through a thrombospondin-independent mechanism. JOURNAL OF BIOLOGICAL CHEMISTRY. 279:54944-54951. Author weblink DOI.
  • Emonard H; Bellon G; Troeberg L; Berton A; Robinet A; Henriet P; Marbaix E; Kirkegaard K; et alPatthy L; Eeckhout Y; Nagase H; Hornebeck W; Courtoy PJ. (24 Dec 2004). Low density lipoprotein receptor-related protein mediates endocytic clearance of pro-MMP-2.TIMP-2 complex through a thrombospondin-independent mechanism. J Biol Chem. 279:54944-54951. DOI.
  • Jain A; Brennan F; Troeberg L; Nanchahal J. (1 Nov 2002). The role of matrix metalloproteinases in rheumatoid tendon disease. JOURNAL OF HAND SURGERY-AMERICAN VOLUME. 27A:1059-1064. Author weblink DOI.
  • Troeberg L; Nagase H. (2003). Measurement of matrix metalloproteinase activities in the medium of cultured synoviocytes using zymography. Methods Mol Biol. 225:77-87. DOI.
  • Troeberg L; Tanaka M; Wait R; Shi YE; Brew K; Nagase H. (17 Dec 2002). E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A). Biochemistry. 41:15025-15035.
  • Jain A; Nanchahal J; Troeberg L; Green P; Brennan F. (Aug 2001). Production of cytokines, vascular endothelial growth factor, matrix metalloproteinases, and tissue inhibitor of metalloproteinases 1 by tenosynovium demonstrates its potential for tendon destruction in rheumatoid arthritis. Arthritis Rheum. 44:1754-1760. DOI.

Conferences

  • Troeberg L; Mulloy B; Lee M-H; Murphy G; Nagase H. Calcium pentosan polysulfate increases affinity between aggrecanases (ADAMTS-4 and-5) and TIMP-3 by a conformational change. Spring Meeting of the British-Society-for-Matrix-Biology, 29 Mar 2010 - 30 Mar 2010. 91:A40-A40. WILEY-BLACKWELL (1 Dec 2010). Author weblink.
  • Sofat N; Troeberg L; Nagase H. The type III 8-10 repeats of fibronectin induce aggrecanase activity via alpha(5)beta(1) integrin and type III 13-14 repeats act via TLR 4 receptors. Annual General Meeting of the British-Society-for-Matrix-Biology, 7 Apr 2008 - 8 Apr 2008. 90:A129-A130. WILEY-BLACKWELL (1 Apr 2009). Author weblink.
  • Miller M-C; Manning HB; Jain A; Troeberg L; Dudhia J; Essex D; Sandison A; Seiki M; et alNanchahal J; Nagase H; Itoh Y. MT1-MMP in human rheumatoid arthritis. Annual General Meeting of the British-Society-for-Matrix-Biology, 7 Apr 2008 - 8 Apr 2008. 90:A97-A97. WILEY-BLACKWELL PUBLISHING, INC (1 Apr 2009). Author weblink.
  • Troeberg L; Nagase H. Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage. Annual General Meeting of the British-Society-for-Matrix-Biology, 7 Apr 2008 - 8 Apr 2008. 90:A67-A67. WILEY-BLACKWELL PUBLISHING, INC (1 Feb 2009). Author weblink.
  • Owen K; Troeberg L; Parker A; Nagase H. Investigation of the endocytic pathway of ADAMTS-4. Annual General Meeting of the British-Society-for-Matrix-Biology, 7 Apr 2008 - 8 Apr 2008. 90:A64-A64. WILEY-BLACKWELL PUBLISHING, INC (1 Feb 2009). Author weblink.
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