Professor Maria G Belvisi

Publications


Journals

  • Clark AR; Belvisi MG. (Apr 2012). Maps and legends: the quest for dissociated ligands of the glucocorticoid receptor. Pharmacol Ther. 134:54-67. DOI.
  • Grace MS; Dubuis E; Birrell MA; Belvisi MG. (Feb 2012). TRP channel antagonists as potential antitussives. Lung. 190:11-15. DOI.
  • Belvisi MG; Dubuis E; Birrell MA. (Oct 2011). Transient receptor potential A1 channels: insights into cough and airway inflammatory disease. Chest. 140:1040-1047. DOI.
  • Eltom S; Stevenson CS; Rastrick J; Dale N; Raemdonck K; Wong S; Catley MC; Belvisi MG; et alBirrell MA. (2011). P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke. PLoS One. 6:e24097. DOI.
  • Raemdonck K; de Alba J; Birrell MA; Grace M; Maher SA; Irvin CG; Fozard JR; O'Byrne PM; et alBelvisi MG. (Jan 2012). A role for sensory nerves in the late asthmatic response. Thorax. 67:19-25. DOI.
  • Belvisi MG; Dale N; Birrell MA; Canning BJ. (Jul 2011). Bronchodilator activity of bitter tastants in human tissue. Nat Med. 17:776. DOI.
  • Maher SA; Dubuis ED; Belvisi MG. (Jun 2011). G-protein coupled receptors regulating cough. Curr Opin Pharmacol. 11:248-253. DOI.
  • Buckley J; Birrell MA; Maher SA; Nials AT; Clarke DL; Belvisi MG. (Dec 2011). EP4 receptor as a new target for bronchodilator therapy. Thorax. 66:1029-1035. DOI.
  • Schmidt LM; Belvisi MG; Bode KA; Bauer J; Schmidt C; Suchy MT; Tsikas D; Scheuerer J; et alLasitschka F; Gröne HJ; Dalpke AH. (15 Feb 2011). Bronchial epithelial cell-derived prostaglandin E2 dampens the reactivity of dendritic cells. J Immunol. 186:2095-2105. DOI.
  • Sadofsky LR; Boa AN; Maher SA; Birrell MA; Belvisi MG; Morice AH. (Jan 2011). TRPA1 is activated by direct addition of cysteine residues to the N-hydroxysuccinyl esters of acrylic and cinnamic acids. Pharmacol Res. 63:30-36. DOI.
  • Slater L; Bartlett NW; Haas JJ; Zhu J; Message SD; Walton RP; Sykes A; Dahdaleh S; et alClarke DL; Belvisi MG; Kon OM; Fujita T; Jeffery PK; Johnston SL; Edwards MR. (2010). Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium. PLoS Pathog. 6:e1001178. DOI.
  • Grace MS; Belvisi MG. (Jun 2011). TRPA1 receptors in cough. Pulm Pharmacol Ther. 24:286-288. DOI.
  • Birrell MA; Van Oosterhout AJ; Belvisi MG. (Nov 2010). Do the current house dust mite-driven models really mimic allergic asthma?. Eur Respir J. 36:1220-1221. DOI.
  • Freund-Michel VC; Birrell MA; Belvisi MG. (1 Aug 2010). Do beta(2)-agonists inhibit capsaicin-induced cough?. EUROPEAN RESPIRATORY JOURNAL. 36:460-461. DOI.
  • Clarke DL; Clifford RL; Jindarat S; Proud D; Pang L; Belvisi MG; Knox AJ. (14 Jul 2010). TNF{alpha} and IFN{gamma} synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-{kappa}B and the transcriptional coactivator CREB-binding protein. J Biol Chem. DOI.
  • Nasra J; Belvisi MG. (Dec 2009). Modulation of sensory nerve function and the cough reflex: understanding disease pathogenesis. Pharmacol Ther. 124:354-375. DOI.
  • Birrell MA; Belvisi MG; Grace M; Sadofsky L; Faruqi S; Hele DJ; Maher SA; Freund-Michel V; et alMorice AH. (1 Dec 2009). TRPA1 Agonists Evoke Coughing in Guinea Pig and Human Volunteers. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 180:1042-1047. Author weblink DOI.
  • Maher SA; Birrell MA; Belvisi MG. (15 Nov 2009). Prostaglandin E2 mediates cough via the EP3 receptor: implications for future disease therapy. Am J Respir Crit Care Med. 180:923-928. DOI.
  • De Alba J; Raemdonck K; Dekkak A; Collins M; Wong S; Nials AT; Knowles RG; Belvisi MG; et alBirrell MA. (Jun 2010). House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?. Eur Respir J. 35:1377-1387. DOI.
  • Maher SA; Belvisi MG. (Jan 2010). Prostanoids and the cough reflex. Lung. 188 Suppl 1:S9-12. DOI.
  • Belvisi MG; Mitchell JA. (Oct 2009). Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease. Br J Pharmacol. 158:994-1003. DOI.
  • Freund-Michel VC; Birrell MA; Giembycz MA; Hele DJ; Haj-Yahia S; Belvisi MG. (Mar 2010). Beta(2)-agonists block tussive responses in guinea pigs via an atypical cAMP-dependent pathway. Eur Respir J. 35:647-654. DOI.
  • Wong S; Belvisi MG; Birrell MA. (3 Aug 2009). MMP/TIMP expression profiles in distinct lung disease models: implications for possible future therapies. RESPIRATORY RESEARCH. 10. Author weblink DOI.
  • Belvisi MG; Hele DJ. (2009). Cough sensors. III. Opioid and cannabinoid receptors on vagal sensory nerves. Handb Exp Pharmacol. 63-76. DOI.
  • Belvisi MG; Patel HJ; Freund-Michel V; Hele DJ; Crispino N; Birrell MA. (Oct 2008). Inhibitory activity of the novel CB2 receptor agonist, GW833972A, on guinea-pig and human sensory nerve function in the airways. Br J Pharmacol. 155:547-557. DOI.
  • Birrell MA; De Alba J; Catley MC; Hardaker E; Wong S; Collins M; Clarke DL; Farrow SN; et alWillson TM; Collins JL; Belvisi MG. (15 Sep 2008). Liver X receptor agonists increase airway reactivity in a model of asthma via increasing airway smooth muscle growth. JOURNAL OF IMMUNOLOGY. 181:4265-4271. Author weblink.
  • Freund-Michel VC; Birrell MA; Patel HJ; Murray-Lyon IM; Belvisi MG. (Sep 2008). Modulation of cholinergic contractions of airway smooth muscle by cathinone: potential beneficial effects in airway diseases. Eur Respir J. 32:579-584. DOI.
  • Catley MC; Birrell MA; Hardaker EL; de Alba J; Farrow S; Haj-Yahia S; Belvisi MG. (1 Jul 2008). Estrogen receptor beta: Expression profile and possible anti-inflammatory role in disease. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. 326:83-88. Author weblink DOI.
  • Belvisi MG; Hele DJ. (1 Jul 2008). Peroxisome proliferator-activated receptors as novel targets in lung disease. CHEST. 134:152-157. Author weblink DOI.
  • Belvisi MG. (2008). Preclinical assessment of novel therapeutics on the cough reflex: cannabinoid agonists as potential antitussives. Lung. 186 Suppl 1:S66-S69. DOI.
  • Birrell MA; Catley MC; Hardaker E; Wong S; Willson TM; McCluskie K; Leonard T; Farrow SN; et alCollins JL; Haj-Yahia S; Belvisi MG. (2 Nov 2007). Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses. JOURNAL OF BIOLOGICAL CHEMISTRY. 282:31882-31890. Author weblink DOI.
  • Morice AH; Fontana GA; Belvisi MG; Birring SS; Chung KF; Dicpinigaitis PV; Kastelik JA; McGarvey LP; et alSmith JA; Tatar M; Widdicombe J; European Respiratory Society (ERS). (Jun 2007). ERS guidelines on the assessment of cough. Eur Respir J. 29:1256-1276. DOI.
  • Birrell MA; Wong S; Catley MC; Belvisi MG. (Jan 2008). Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages. J Cell Physiol. 214:27-37. DOI.
  • Moschos SA; Williams AE; Perry MM; Birrell MA; Belvisi MG; Lindsay MA. (2007). Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids. BMC Genomics. 8:240. DOI.
  • Birrell MA; McCluskie K; Hardaker E; Knowles R; Belvisi MG. (Dec 2006). Utility of exhaled nitric oxide as a noninvasive biomarker of lung inflammation in a disease model. Eur Respir J. 28:1236-1244. DOI.
  • Birrell MA; Wong S; Dekkak A; De Alba J; Haj-Yahia S; Belvisi MG. (Aug 2006). Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease. J Pharmacol Exp Ther. 318:741-750. DOI.
  • Belvisi MG; Birrell M; Wong S; Hardaker E; Catley M; McCluskie K. (1 Jul 2006). Pharmacological approaches for the treatment of COPD. ACTA PHARMACOLOGICA SINICA. 27:37-38. Author weblink.
  • Birrell MA; Wong S; Hardaker EL; Catley MC; McCluskie K; Collins M; Haj-Yahia S; Belvisi MG. (Jun 2006). IkappaB kinase-2-independent and -dependent inflammation in airway disease models: relevance of IKK-2 inhibition to the clinic. Mol Pharmacol. 69:1791-1800. DOI.
  • Belvisi MG; Hele DJ; Birrell MA. (8 Mar 2006). Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation. Eur J Pharmacol. 533:101-109. DOI.
  • Birrell MA; Wong S; McCluskie K; Catley MC; Hardaker EL; Haj-Yahia S; Belvisi MG. (Mar 2006). Second-generation inhibitors demonstrate the involvement of p38 mitogen-activated protein kinase in post-transcriptional modulation of inflammatory mediator production in human and rodent airways. J Pharmacol Exp Ther. 316:1318-1327. DOI.
  • Birrell MA; Hardaker E; Wong S; McCluskie K; Catley M; De Alba J; Newton R; Haj-Yahia S; et alPun KT; Watts CJ; Shaw RJ; Savage TJ; Belvisi MG. (15 Oct 2005). I kappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 172:962-971. Author weblink DOI.
  • Belvisi MG; Bundschuh DS; Stoeck M; Wicks S; Underwood S; Battram CH; Haddad ELB; Webber SE; et alFoster ML. (Aug 2005). Preclinical profile of ciclesonide, a novel corticosteroid for the treatment of asthma. J Pharmacol Exp Ther. 314:568-574. DOI.
  • Birrell MA; Wong S; Hele DJ; McCluskie K; Hardaker E; Belvisi MG. (1 Jul 2005). Steroid-resistant inflammation in a rat model of chronic obstructive pulmonary disease is associated with a lack of nuclear factor-kappaB pathway activation. Am J Respir Crit Care Med. 172:74-84. DOI.
  • Belvisi MG; Broadley K. (1 Jun 2005). Don't forget the nose and pulmonary circulation! Editorial overview. CURRENT OPINION IN PHARMACOLOGY. 5:211-213. Author weblink DOI.
  • Birrell MA; McCluskie K; Wong SS; Donnelly LE; Barnes PJ; Belvisi MG. (1 Feb 2005). Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF-kappa B-independent mechanism. FASEB JOURNAL. 19:840-+. Author weblink DOI.
  • Clarke DL; Belvisi MG; Smith SJ; Hardaker E; Yacoub MH; Meja KK; Newton R; Slater DM; et alGiembycz MA. (Feb 2005). Prostanoid receptor expression by human airway smooth muscle cells and regulation of the secretion of granulocyte colony-stimulating factor. Am J Physiol Lung Cell Mol Physiol. 288:L238-L250. DOI.
  • Clarke DL; Belvisi MG; Hardaker E; Newton R; Giembycz MA. (Feb 2005). E-ring 8-isoprostanes are agonists at EP2- and EP4-prostanoid receptors on human airway smooth muscle cells and regulate the release of colony-stimulating factors by activating cAMP-dependent protein kinase. Mol Pharmacol. 67:383-393. DOI.
  • Usmani OS; Belvisi MG; Patel HJ; Crispino N; Birrell MA; Korbonits M; Korbonits D; Barnes PJ. (Feb 2005). Theobromine inhibits sensory nerve activation and cough. FASEB J. 19:231-233. DOI.
  • McCluskie K; Birrell MA; Wong S; Belvisi MG. (Nov 2004). Nitric oxide as a noninvasive biomarker of lipopolysaccharide-induced airway inflammation: possible role in lung neutrophilia. J Pharmacol Exp Ther. 311:625-633. DOI.
  • Belvisi MG; Hele DJ; Birrell MA. (Aug 2004). New anti-inflammatory therapies and targets for asthma and chronic obstructive pulmonary disease. Expert Opin Ther Targets. 8:265-285. DOI.
  • Birrell MA; Patel HJ; McCluskie K; Wong S; Leonard T; Yacoub MH; Belvisi MG. (Jul 2004). PPAR-gamma agonists as therapy for diseases involving airway neutrophilia. Eur Respir J. 24:18-23.
  • Belvisi MG; Geppetti P. (1 May 2004). Cough center dot 7: Current and future drugs for the treatment of chronic cough. THORAX. 59:438-440. Author weblink DOI.
  • Belvisi MG; Geppetti P. (May 2004). Cough. 7: Current and future drugs for the treatment of chronic cough. Thorax. 59:438-440.
  • Clarke DL; Belvisi MG; Catley MC; Yacoub MH; Newton R; Giembycz MA. (Apr 2004). Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF. Br J Pharmacol. 141:1141-1150. DOI.
  • Clarke DL; Giembycz MA; Patel HJ; Belvisi MG. (Feb 2004). E-ring 8-isoprostanes inhibit ACh release from parasympathetic nerves innervating guinea-pig trachea through agonism of prostanoid receptors of the EP3-subtype. Br J Pharmacol. 141:600-609. DOI.
  • Belvisi MG. (2004). Regulation of inflammatory cell function by corticosteroids. Proc Am Thorac Soc. 1:207-214. DOI.
  • Belvisi MG; Hele DJ; Birrell MA. (2004). New advances and potential therapies for the treatment of asthma. BioDrugs. 18:211-223.
  • Belvisi MG. (1 Jan 2004). Ciclesonide - A viewpoint. DRUGS. 64:520-520. Author weblink DOI.
  • Patel HJ; Birrell MA; Crispino N; Hele DJ; Venkatesan P; Barnes PJ; Yacoub MH; Belvisi MG. (Sep 2003). Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation. Br J Pharmacol. 140:261-268. DOI.
  • Belvisi MG. (Jun 2003). Airway sensory innervation as a target for novel therapies: an outdated concept?. Curr Opin Pharmacol. 3:239-243.
  • Birrell MA; Battram CH; Woodman P; McCluskie K; Belvisi MG. (21 Mar 2003). Dissociation by steroids of eosinophilic inflammation from airway hyperresponsiveness in murine airways. RESPIRATORY RESEARCH. 4. Author weblink DOI.
  • Belvisi MG; Bottomley KM. (Mar 2003). The role of matrix metalloproteinases (MMPs) in the pathophysiology of chronic obstructive pulmonary disease (COPD): a therapeutic role for inhibitors of MMPs?. Inflamm Res. 52:95-100.
  • Patel HJ; Belvisi MG; Bishop-Bailey D; Yacoub MH; Mitchell JA. (1 Mar 2003). Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. J Immunol. 170:2663-2669.
  • Birrell MA; McCluskie K; Haddad ELB; Battram CH; Webber SE; Foster ML; Yacoub MH; Belvisi MG. (Mar 2003). Pharmacological assessment of the nitric-oxide synthase isoform involved in eosinophilic inflammation in a rat model of sephadex-induced airway inflammation. J Pharmacol Exp Ther. 304:1285-1291. DOI.
  • Belvisi MG; Hele DJ. (2003). Soft steroids: a new approach to the treatment of inflammatory airways diseases. Pulm Pharmacol Ther. 16:321-325. DOI.
  • Hele DJ; Belvisi MG. (Jan 2003). Novel therapies for the treatment of inflammatory airway disease. Expert Opin Investig Drugs. 12:5-18. DOI.
  • Belvisi MG. (2003). Sensory nerves and airway inflammation: role of A delta and C-fibres. Pulm Pharmacol Ther. 16:1-7. DOI.
  • Underwood SL; Haddad ELB; Birrell MA; McCluskie K; Pecoraro M; Dabrowski D; Webber SE; Foster ML; et alBelvisi MG. (Sep 2002). Functional characterization and biomarker identification in the Brown Norway model of allergic airway inflammation. Br J Pharmacol. 137:263-275. DOI.
  • Haddad ELB; McCluskie K; Birrell MA; Dabrowski D; Pecoraro M; Underwood S; Chen B; De Sanctis GT; et alWebber SE; Foster ML; Belvisi MG. (15 Jul 2002). Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation. J Immunol. 169:974-982.
  • Birrell MA; Crispino N; Hele DJ; Patel HJ; Yacoub MH; Barnes PJ; Belvisi MG. (Jun 2002). Effect of dopamine receptor agonists on sensory nerve activity: possible therapeutic targets for the treatment of asthma and COPD. Br J Pharmacol. 136:620-628. DOI.
  • Belvisi MG. (Jun 2002). Overview of the innervation of the lung. Curr Opin Pharmacol. 2:211-215.
  • Parikh A; Scadding GK; Gray P; Belvisi MG; Mitchell JA. (Apr 2002). High levels of nitric oxide synthase activity are associated with nasal polyp tissue from aspirin-sensitive asthmatics. Acta Otolaryngol. 122:302-305.
  • Haddad ELB; Underwood SL; Dabrowski D; Birrell MA; McCluskie K; Battram CH; Pecoraro M; Foster ML; et alBelvisi MG. (15 Mar 2002). Critical role for T cells in Sephadex-induced airway inflammation: pharmacological and immunological characterization and molecular biomarker identification. J Immunol. 168:3004-3016.
  • Clarke DL; Belvisi MG; Patel HJ; Yacoub MH; Giembycz MA. (1 Mar 2002). Prostaglandin E-2 inhibits GM-CSF release from interleukin-1 beta-stimulated human airway smooth muscle cells by interacting with prostanoid receptors of the EP2-subtype. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • McCluskie K; Birrell MA; Yacoub MH; Mitchell JA; Belvisi MG. (1 Mar 2002). The role of nitric oxide synthase in antigen-induced airway eosinophilia in the rat. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Birrell M; McCluskie K; Yacoub MH; Belvisi MG. (1 Mar 2002). The role of nitric oxide synthase in an acute model of LPS-induced airway inflammation in the rat. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Clarke DL; Giembycz MA; Yacoub MH; Belvisi MG. (1 Mar 2002). Regulation of the release of colony-stimulating factors from human airway smooth muscle cells by isoprostanes. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Birrell MA; McCluskie K; Wong S; Yacoub MH; Belvisi MG. (1 Mar 2002). Characterisation of an acute model of COPD in the rat. BRITISH JOURNAL OF PHARMACOLOGY. 135. Author weblink.
  • Spicuzza L; Basile L; Belvisi MG; Bellofiore S; Matera MG; Cazzola M; Di Maria GU. (2002). The protective role of epithelium-derived nitric oxide in isolated bovine trachea. Pulm Pharmacol Ther. 15:357-362. DOI.
  • Bottomley KM; Belvisi MG. (1 Jan 2002). Matrix metalloproteinases and the potential therapeutic role for matrix metalloproteinase inhibitors in chronic obstructive pulmonary disease (COPD). ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 37. 37:209-216. Author weblink DOI.
  • Belvisi MG; Bolser DC. (2002). Summary: animal models for cough. Pulm Pharmacol Ther. 15:249-250. DOI.
  • Lazzeri N; Belvisi MG; Patel HJ; Chung KF; Yacoub MH; Mitchell JA. (21 Dec 2001). RANTES release by human airway smooth muscle: effects of prostaglandin E(2) and fenoterol. Eur J Pharmacol. 433:231-235.
  • Spicuzza L; Belvisi MG; Birrell MA; Barnes PJ; Hele DJ; Giembycz MA. (Aug 2001). Evidence that the anti-spasmogenic effect of the beta-adrenoceptor agonist, isoprenaline, on guinea-pig trachealis is not mediated by cyclic AMP-dependent protein kinase. Br J Pharmacol. 133:1201-1212. DOI.
  • Fox AJ; Patel HJ; Barnes PJ; Belvisi MG. (20 Jul 2001). Release of nerve growth factor by human pulmonary epithelial cells: role in airway inflammatory diseases. Eur J Pharmacol. 424:159-162.
  • Patel HJ; Belvisi MG; Bishop-Bailey D; Yacoub MH; Mitchell JA. (1 May 2001). Evidence for an anti-proliferative role of peroxisome-proliferator-activated receptors in human airway smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 133:U24-U24. Author weblink.
  • Clarke DL; Patel HJ; Mitchell JA; Yacoub MH; Giembycz MA; Belvisi MG. (1 May 2001). Regulation of the release of colony-stimulating factors from human airway smooth muscle cells by prostaglandin E-2. BRITISH JOURNAL OF PHARMACOLOGY. 133:U23-U23. Author weblink.
  • Birrell M; McCluskie K; Yacoub MH; Belvisi MG. (1 May 2001). Effect of the HMG-CoA reductase inhibitor, pravastatin, on sephadex-induced airway inflammation in the rat. BRITISH JOURNAL OF PHARMACOLOGY. 133:U105-U105. Author weblink.
  • Haddad EB; Birrell M; McCluskie K; Ling A; Webber SE; Foster ML; Belvisi MG. (Apr 2001). Role of p38 MAP kinase in LPS-induced airway inflammation in the rat. Br J Pharmacol. 132:1715-1724. DOI.
  • Spicuzza L; Barnes PJ; Di Maria GU; Belvisi MG. (30 Mar 2001). Effect of 8-iso-prostaglandin F(2 alpha) on acetylcholine release from parasympathetic nerves in guinea pig airways. Eur J Pharmacol. 416:231-234.
  • Finney PA; Donnelly LE; Belvisi MG; Chuang TT; Birrell M; Harris A; Mak JC; Scorer C; et alBarnes PJ; Adcock IM; Giembycz MA. (Mar 2001). Chronic systemic administration of salmeterol to rats promotes pulmonary beta(2)-adrenoceptor desensitization and down-regulation of G(s alpha). Br J Pharmacol. 132:1261-1270. DOI.
  • Belvisi MG; Wicks SL; Battram CH; Bottoms SE; Redford JE; Woodman P; Brown TJ; Webber SE; et alFoster ML. (1 Feb 2001). Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity. J Immunol. 166:1975-1982.
  • Mclay LM; Halley F; Souness JE; McKenna J; Benning V; Birrell M; Burton B; Belvisi M; et alCollis A; Constan A; Foster M; Hele D; Jayyosi Z; Kelley M; Maslen C; Miller G; Ouldelhkim MC; Page K; Phipps S; Pollock K; Porter B; Ratcliffe AJ; Redford EJ; Webber S; Slater B; Thybaud V; Wilsher N. (Feb 2001). The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy. Bioorg Med Chem. 9:537-554.
  • Hele DJ; Yacoub MH; Belvisi MG. (2001). The heterotopic tracheal allograft as an animal model of obliterative bronchiolitis. Respir Res. 2:169-183.
  • Belvisi MG; Brown TJ; Wicks S; Foster ML. (2001). New Glucocorticosteroids with an improved therapeutic ratio?. Pulm Pharmacol Ther. 14:221-227. DOI.
  • Lazzeri N; Belvisi MG; Patel HJ; Yacoub MH; Chung KF; Mitchell JA. (Jan 2001). Effects of prostaglandin E2 and cAMP elevating drugs on GM-CSF release by cultured human airway smooth muscle cells. Relevance to asthma therapy. Am J Respir Cell Mol Biol. 24:44-48.
  • Hele DJ; Birrell MA; Webber SE; Foster ML; Belvisi MG. (Jan 2001). Mediator involvement in antigen-induced bronchospasm and microvascular leakage in the airways of ovalbumin sensitized Brown Norway rats. Br J Pharmacol. 132:481-488. DOI.
  • Hele DJ; Birrell MA; Webber SE; Foster ML; Belvisi MG. (Nov 2000). Effect of endothelin antagonists, including the novel ET(A) receptor antagonist LBL 031, on endothelin-1 and lipopolysaccharide-induced microvascular leakage in rat airways. Br J Pharmacol. 131:1129-1134. DOI.
  • Birrell M; Hele D; McCluskie K; Webber S; Foster M; Belvisi MG. (Nov 2000). Effect of the p38 kinase inhibitor, SB 203580, on sephadex induced airway inflammation in the rat. Eur Respir J. 16:947-950.
  • Escott KJ; Belvisi MG; Birrell MA; Webber SE; Foster ML; Sargent CA. (Sep 2000). Effect of the p38 kinase inhibitor, SB 203580, on allergic airway inflammation in the rat. Br J Pharmacol. 131:173-176. DOI.
  • Spicuzza L; Haddad EB; Birrell M; Ling A; Clarke D; Venkatesan P; Barnes PJ; Belvisi MG. (Aug 2000). Characterization of the effects of cannabinoids on guinea-pig tracheal smooth muscle tone: role in the modulation of acetylcholine release from parasympathetic nerves. Br J Pharmacol. 130:1720-1726. DOI.
  • Finney PA; Belvisi MG; Donnelly LE; Chuang TT; Mak JC; Scorer C; Barnes PJ; Adcock IM; et alGiembycz MA. (Jul 2000). Albuterol-induced downregulation of Gsalpha accounts for pulmonary beta(2)-adrenoceptor desensitization in vivo. J Clin Invest. 106:125-135. DOI.
  • Belvisi MG; Haddad EB; Battram C; Birrell M; Foster M; Webber S. (Mar 2000). Anti-inflammatory properties of ebselen in a model of sephadex-induced lung inflammation. Eur Respir J. 15:579-581.
  • McCluskie K; Haddad EB; Birrell MA; Webber SE; Foster M; Belvisi MG. (1 Jan 2000). The effect of the seleno-organic compound ebselen on LPS-induced airway inflammation. BRITISH JOURNAL OF PHARMACOLOGY. 129:U121-U121. Author weblink.
  • Birrell MA; Battram CH; Haddad EB; McCluskie K; Bohme GA; Webber SE; Foster ML; Belvisi MG. (1 Jan 2000). The role of inducible nitric oxide synthase in sephadex-induced airway inflammation in the rat. BRITISH JOURNAL OF PHARMACOLOGY. 129. Author weblink.
  • Birrell MA; Battram CH; McCluskie K; Pecoraro M; Webber SE; Foster ML; Belvisi MG. (1 Jan 2000). Effect of the p38 kinase inhibitor, SB203580, on sephadex-induced airway inflammation in the rat. BRITISH JOURNAL OF PHARMACOLOGY. 129:U119-U119. Author weblink.
  • Hele DJ; Birrell MA; Webber SE; Foster M; Belvisi MG. (1 Jan 2000). Mediator involvement in antigen-induced microvascular leakage into the airways and bronchospasm in ovalbumin sensitised brown Norway rats. BRITISH JOURNAL OF PHARMACOLOGY. 129:U119-U119. Author weblink.
  • Battram CH; Birrell M; Foster M; Webber SE; Belvisi MG. (1 Nov 1999). Comparison of inhaled spasmogen as determinants of airway hyperresponsiveness in a murine model of asthma. BRITISH JOURNAL OF PHARMACOLOGY. 128:U29-U29. Author weblink.
  • Patel HJ; Belvisi MG; Donnelly LE; Yacoub MH; Chung KF; Mitchell JA. (Oct 1999). Constitutive expressions of type I NOS in human airway smooth muscle cells: evidence for an antiproliferative role. FASEB J. 13:1810-1816.
  • Bernareggi MM; Belvisi MG; Patel H; Barnes PJ; Giembycz MA. (Sep 1999). Anti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis. Br J Pharmacol. 128:327-336. DOI.
  • Patel HJ; Venkatesan P; Halfpenny J; Yacoub MH; Fox A; Barnes PJ; Belvisi MG. (11 Jun 1999). Modulation of acetylcholine release from parasympathetic nerves innervating guinea-pig and human trachea by endomorphin-1 and -2. Eur J Pharmacol. 374:21-24.
  • Haddad EB; Patel H; Keeling JE; Yacoub MH; Barnes PJ; Belvisi MG. (May 1999). Pharmacological characterization of the muscarinic receptor antagonist, glycopyrrolate, in human and guinea-pig airways. Br J Pharmacol. 127:413-420. DOI.
  • Lazzeri N; Belvisi MG; Patel HJ; Yacoub MH; Chung KF; Mitchell JA. (1 Mar 1999). Inhibitors of phosphodiesterase type 4 enzymes inhibit RANTES release by cytokine treated human airway smooth muscle cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A401-A401.
  • Finney PA; Belvisi MG; Barnes PJ; Donnelly LE; Adcock IM; Giembycz MA. (1 Mar 1999). In vivo heterologous desensitisation of pulmonary beta(2)-adrenoceptors in Sprague-Dawley rats after chronic treatment with salmeterol. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A396-A396. Author weblink.
  • Spicuzza L; Mistretta A; Belvisi MG; Di Maria GU. (1 Mar 1999). Antispasmogenic role of epithelium-derived nitric oxide (NO) in isolated bovine trachea. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A410-A410. Author weblink.
  • Patel HJ; Douglas GJ; Herd CM; Spina D; Giembycz MA; Barnes PJ; Belvisi MG; Page CP. (1 Mar 1999). Sensitization of rabbits to allergen increases acetylcholine release from rabbit airways but is not associated with alterations in M-2-receptor function. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A535-A535. Author weblink.
  • Spicuzza L; Patel HJ; Venkatesari P; Barnes PJ; Belvisi MG. (1 Mar 1999). Effect of cannabinoid receptor agonists on cholinergic neurotransmission in guinea-pig trachea. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A536-A536. Author weblink.
  • Saunders MA; Belvisi MG; Cirino G; Barnes PJ; Warner TD; Mitchell JA. (Mar 1999). Mechanisms of prostaglandin E2 release by intact cells expressing cyclooxygenase-2: evidence for a 'two-component' model. J Pharmacol Exp Ther. 288:1101-1106.
  • Hele DJ; Birrell M; Foster M; Webber SE; Belvisi MG. (1 Mar 1999). The effect of endothelin antagonists on endothelin-1 and lipopolysaccharide-induced microvascular leakage in rat airways. BRITISH JOURNAL OF PHARMACOLOGY. 126:U84-U84. Author weblink.
  • Patel HJ; Belvisi MG; Fadlon EJ; Rousell J; Haddad EB; Jose PJ; Mitchell JA; Chung KF. (1 Mar 1999). Induction of eotaxin expression and release from human airway smooth muscle cells by IL-1 beta & TNF alpha: Effects of IL-10 and corticosteroids. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A401-A401. Author weblink.
  • Lazzeri N; Mitchell JA; Patel HJ; Yacoub MH; Chung KF; Belvisi MG. (1 Mar 1999). Inhibitors of phosphodiesterase type 4 enzymes inhibit GMCSF release by cytokine treated human airway smooth muscle cells. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A395-A395. Author weblink.
  • Battram CH; Birrell MA; Ling A; Webber SE; Belvisi MG. (1 Mar 1999). The time course of sephadex-induced rat lung inflammation and a comparison of the activity of various anti-inflammatory drugs. BRITISH JOURNAL OF PHARMACOLOGY. 126:U85-U85. Author weblink.
  • Belvisi MG; Hele DJ; Birrell M; Foster M; Webber SE. (1 Mar 1999). The effect of endothelin antagonists on endothelin-1 and lipopolysaccharide-induced microvascular leakage in rat airways. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A330-A330. Author weblink.
  • Patel HJ; Belvisi MG; Donnelly LE; Yacoub MH; Chung KF; Mitchell JA. (1 Mar 1999). Constitutive expression of nNOS in human cultured airway smooth muscle cells: Evidence for an anti-proliferative role. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A531-A531. Author weblink.
  • Patel HJ; Halfpenny J; Venkatesan P; Barnes PJ; Yacoub MH; Fox A; Belvisi MG. (1 Mar 1999). Modulation of acetylcholine release from cholinergic nerves innervating human and guinea-pig trachea by endomorphin-1 and-2. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A535-A535. Author weblink.
  • Belvisi MG; Wicks S; Battram C; Bottoms S; Redford J; Webber S; Foster M. (1 Mar 1999). Does the synthetic glucocorticoid, RU 24858, which dissociates transactivation and transrepression in vitro possess anti-inflammatory properties without steroid adverse side effects in vivo?. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A108-A108. Author weblink.
  • Haddad EB; McCluskie K; Birrell MA; Webber SE; Belvisi MG. (1 Mar 1999). Effect of Ebselen on LPS-induced airway inflammation in the rat. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A331-A331. Author weblink.
  • Venkatesan P; Fox A; Barnes PJ; Belvisi MG. (1 Mar 1999). Effect of endomorphin 1 & 2 on vagal sensory activity and cough. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A534-A534. Author weblink.
  • Haddad EB; Birrell MA; McCluskie K; Hele D; Ling A; Foster M; Webber SE; Belvisi MG. (1 Mar 1999). Effect of the P38 kinase inhibitor, SB 203580, on IL-1 beta levels and cell influx in a model of airway inflammation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A331-A331. Author weblink.
  • Belvisi MG; Battram CH; Birrell MA; Ling A; Webber SE. (1 Mar 1999). Characterisation of an acute rat lung oedema model. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 159:A330-A330. Author weblink.
  • Patel HJ; Douglas GJ; Herd CM; Spina D; Giembycz MA; Barnes PJ; Belvisi MG; Page CP. (1999). Antigen-induced bronchial hyperresponsiveness in the rabbit is not dependent on M(2)-receptor dysfunction. Pulm Pharmacol Ther. 12:245-255. DOI.
  • Liu YC; Patel HJ; Khawaja AM; Belvisi MG; Rogers DF. (Jan 1999). Neuroregulation by vasoactive intestinal peptide (VIP) of mucus secretion in ferret trachea: activation of BK(Ca) channels and inhibition of neurotransmitter release. Br J Pharmacol. 126:147-158. DOI.
  • Patel HJ; Halfpenny J; Venkatesan P; Barnes PJ; Yacoub MH; Fox A; Belvisi MG. (1 Dec 1998). Modulation of acetylcholine release from cholinergic nerves innervating human and guinea-pig trachea by endomorphin-1 and -2. BRITISH JOURNAL OF PHARMACOLOGY. 125:U6-U6. Author weblink.
  • Birrell M; Haddad EB; McCluskie K; Hele D; Phipps S; Webber SE; Foster M; Belvisi MG. (1 Dec 1998). Effect of the p38 kinase inhibitor, SB203580, in a model of airway inflammation. BRITISH JOURNAL OF PHARMACOLOGY. 125:U46-U46. Author weblink.
  • Belvisi MG; Saunders M; Yacoub M; Mitchell JA. (Nov 1998). Expression of cyclo-oxygenase-2 in human airway smooth muscle is associated with profound reductions in cell growth. Br J Pharmacol. 125:1102-1108. DOI.
  • Patel HJ; Giembycz MA; Keeling JE; Barnes PJ; Belvisi MG. (Aug 1998). Inhibition of cholinergic neurotransmission in guinea pig trachea by NS1619, a putative activator of large-conductance, calcium-activated potassium channels. J Pharmacol Exp Ther. 286:952-958.
  • Mitchell JA; Belvisi MG. (1 Aug 1998). Cyclo-oxygenase - Reply. THORAX. 53:719-720. Author weblink.
  • Spicuzza L; Giembycz MA; Barnes PJ; Belvisi MG. (Mar 1998). Prostaglandin E2 suppression of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by interacting with prostanoid receptors of the EP3-subtype. Br J Pharmacol. 123:1246-1252. DOI.
  • Mitchell JA; Bishop-Bailey D; Evans TW; Giembycz MA; Belvisi MG; Chivers S; Williams TJ; Pepper JR. (1 Mar 1998). Release of neutrophil activating cytokines by human arterial and venous smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 123:U56-U56. Author weblink.
  • Cirino G; Saunders M; Belvisi MG; Jourdan KB; Evans TW; Coppini A; Mitchell JA. (1 Mar 1998). Relative potencies of nonsteroidal anti-inflammatory drugs on purified cyclo-oxygenase-1 and -2. BRITISH JOURNAL OF PHARMACOLOGY. 123:U101-U101. Author weblink.
  • Finney PA; Belvisi MG; Adcock IM; Donnelly LE; Barnes PJ; Giembycz MA. (1 Jan 1998). Chronic treatment with salbutamol causes in vivo heterologous desensitisation of beta(2)-adrenoceptors and down-regulation of G(s alpha) in Sprague-Dawley rats. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 358:R648-R648. Author weblink.
  • Belvisi MG; Haddad EB; Battram C; Birrell M; Webber SW. (1 Jan 1998). In vivo anti-inflammatory properties of ebselen in a model of sephadex-induced lung inflammation in the rat. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 358:R329-R329. Author weblink.
  • Patel HJ; Mitchell JA; Chung FK; Belvisi MG. (1 Jan 1998). Endogenous nitric oxide suppresses growth of human ASM cells. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 358:R310-R310. Author weblink.
  • Escott KJ; Birrell MA; McCluskie K; Belvisi MG; McMillan SJ; Webber SE; Sargent CA. (1 Jan 1998). Effect of SB203580 on murine airway inflammation. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 358:R329-R329. Author weblink.
  • John M; Au BT; Jose PJ; Lim S; Saunders M; Barnes PJ; Mitchell JA; Belvisi MG; et alChung KF. (Jan 1998). Expression and release of interleukin-8 by human airway smooth muscle cells: inhibition by Th-2 cytokines and corticosteroids. Am J Respir Cell Mol Biol. 18:84-90.
  • Battram CH; Birrell M; McCluskie K; Foster M; Belvisi MG; Webber SE. (1 Dec 1997). A method for measuring airways mechanics and hyper-responsiveness in spontaneously breathing mice. BRITISH JOURNAL OF PHARMACOLOGY. 122:U130-U130. Author weblink.
  • Mitchell JA; Belvisi MG. (Nov 1997). Too many COX (cyclo-oxygenase) spoil the broth: aspirin-sensitive asthma and 5-lypoxygenase. Thorax. 52:933-935.
  • Mitchell JA; Saunders M; Barnes PJ; Newton R; Belvisi MG. (Jun 1997). Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 51:907-912.
  • Takahashi T; Barnes PJ; Kawikova I; Yacoub MH; Warner TD; Belvisi MG. (18 Apr 1997). Contraction of human airway smooth muscle by endothelin-1 and IRL 1620: effect of bosentan. Eur J Pharmacol. 324:219-222.
  • Bernareggi M; Mitchell JA; Barnes PJ; Belvisi MG. (Mar 1997). Dual action of nitric oxide on airway plasma leakage. Am J Respir Crit Care Med. 155:869-874.
  • Patel HJ; Giembycz MA; Spicuzza L; Barnes PJ; Belvisi MG. (Mar 1997). Naloxone-insensitive inhibition of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by the novel opioid, nociceptin. Br J Pharmacol. 120:735-736. DOI.
  • Belvisi MG; Saunders MA; Haddad el-B; Hirst SJ; Yacoub MH; Barnes PJ; Mitchell JA. (Mar 1997). Induction of cyclo-oxygenase-2 by cytokines in human cultured airway smooth muscle cells: novel inflammatory role of this cell type. Br J Pharmacol. 120:910-916. DOI.
  • Fox AJ; Barnes PJ; Venkatesan P; Belvisi MG. (1 Feb 1997). Activation of large conductance potassium channels inhibits the afferent and efferent function of airway sensory nerves in the guinea pig. J Clin Invest. 99:513-519. DOI.
  • Saunders MA; Mitchell JA; Seldon PM; Yacoub MH; Barnes PJ; Giembycz MA; Belvisi MG. (Feb 1997). Release of granulocyte-macrophage colony stimulating factor by human cultured airway smooth muscle cells: suppression by dexamethasone. Br J Pharmacol. 120:545-546. DOI.
  • Patel HJ; Giembycz MA; Keeling JEA; Barnes PJ; Belvisi MG. (1 Oct 1996). Role of large-conductance calcium-activated potassium channels in the regulation of acetylcholine release by pre-junctional M(2)-muscarinic receptors. BRITISH JOURNAL OF PHARMACOLOGY. 119:P42-P42. Author weblink.
  • Saunders MA; Belvisi MG; Corden MB; Fox AJ; Evans TW; Barnes PJ; Mitchell JA. (1 Oct 1996). Exacerbation of the release of prostaglandin E(2) by bradykinin after COX-2 induction in human airway epithelial cells. BRITISH JOURNAL OF PHARMACOLOGY. 119:P46-P46. Author weblink.
  • Fox AJ; Lalloo UG; Belvisi MG; Bernareggi M; Chung KF; Barnes PJ. (Jul 1996). Bradykinin-evoked sensitization of airway sensory nerves: a mechanism for ACE-inhibitor cough. Nat Med. 2:814-817.
  • Haddad EB; Mak JC; Belvisi MG; Nishikawa M; Rousell J; Barnes PJ. (Jun 1996). Muscarinic and beta-adrenergic receptor expression in peripheral lung from normal and asthmatic patients. Am J Physiol. 270:L947-L953.
  • Bernareggi M; Mitchell JA; Barnes PJ; Belvisi MG. (1 Apr 1996). Dual action of nitric oxide on airway inflammation: Differential effects at different airway levels. BRITISH JOURNAL OF PHARMACOLOGY. 117:P52-P52. Author weblink.
  • Saunders MA; Mitchell JA; HIrst SJ; Williams TJ; Yacoub MH; Barnes PJ; Belvisi MG. (1 Apr 1996). Characterisation of cyclo-oxygenase-2 induction in human airway smooth muscle cells. BRITISH JOURNAL OF PHARMACOLOGY. 117:P82-P82. Author weblink.
  • Belvisi MG; Patel HJ; Takahashi T; Barnes PJ; Giembycz MA. (Apr 1996). Paradoxical facilitation of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by isoprenaline. Br J Pharmacol. 117:1413-1420.
  • Kawikova I; Barnes PJ; Takahashi T; Tadjkarimi S; Yacoub MH; Belvisi MG. (Feb 1996). 8-Epi-PGF2 alpha, a novel noncyclooxygenase-derived prostaglandin, constricts airways in vitro. Am J Respir Crit Care Med. 153:590-596.
  • Lalloo UG; Fox AJ; Belvisi MG; Chung KF; Barnes PJ. (Oct 1995). Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs. J Appl Physiol. 79:1082-1087.
  • Patel HJ; Barnes PJ; Takahashi T; Tadjkarimi S; Yacoub MH; Belvisi MG. (Sep 1995). Evidence for prejunctional muscarinic autoreceptors in human and guinea pig trachea. Am J Respir Crit Care Med. 152:872-878.
  • Ward JK; Barnes PJ; Springall DR; Abelli L; Tadjkarimi S; Yacoub MH; Polak JM; Belvisi MG. (Aug 1995). Distribution of human i-NANC bronchodilator and nitric oxide-immunoreactive nerves. Am J Respir Cell Mol Biol. 13:175-184.
  • Takahashi T; Ward JK; Tadjkarimi S; Yacoub MH; Barnes PJ; Belvisi MG. (Jul 1995). 5-Hydroxytryptamine facilitates cholinergic bronchoconstriction in human and guinea pig airways. Am J Respir Crit Care Med. 152:377-380.
  • Ward JK; Barnes PJ; Tadjkarimi S; Yacoub MH; Belvisi MG. (1 Mar 1995). Evidence for the involvement of cGMP in neural bronchodilator responses in humal trachea. J Physiol. 483 ( Pt 2):525-536.
  • WARD JK; BARNES PJ; TADJKARIMI S; YACOUB MH; BELVISI MG. (1 Mar 1995). EVIDENCE FOR THE INVOLVEMENT OF CGMP IN NEURAL BRONCHODILATOR RESPONSES IN HUMAN TRACHEA. JOURNAL OF PHYSIOLOGY-LONDON. 483:525-536. Author weblink.
  • Barnes PJ; Belvisi MG; Mak JC; Haddad EB; O'Connor B. (1995). Tiotropium bromide (Ba 679 BR), a novel long-acting muscarinic antagonist for the treatment of obstructive airways disease. Life Sci. 56:853-859.
  • Belvisi MG; Ward JK; Mitchell JA; Barnes PJ. (Jan 1995). Nitric oxide as a neurotransmitter in human airways. Arch Int Pharmacodyn Ther. 329:97-110.
  • Takahashi T; Belvisi MG; Patel H; Ward JK; Tadjkarimi S; Yacoub MH; Barnes PJ. (Dec 1994). Effect of Ba 679 BR, a novel long-acting anticholinergic agent, on cholinergic neurotransmission in guinea pig and human airways. Am J Respir Crit Care Med. 150:1640-1645.
  • Mitchell JA; Belvisi MG; Akarasereenont P; Robbins RA; Kwon OJ; Croxtall J; Barnes PJ; Vane JR. (Nov 1994). Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone. Br J Pharmacol. 113:1008-1014.
  • MITCHELL JA; BELVISI MG; ROBBINS RA; KWON OJ; BARNES PJ; VANE J. (1 May 1994). INDUCTION OF CYCLOOXYGENASE-2 IN HUMAN PULMONARY EPITHELIAL-CELLS. BRITISH JOURNAL OF PHARMACOLOGY. 112:U41-U41. Author weblink.
  • WARD JK; BARNES PJ; TADJKARIMI S; KELLY JJ; YACOUB MH; BELVISI MG. (1 May 1994). NONADRENERGIC NONCHOLINERGIC NEURAL RELAXATION IN HUMAN TRACHEAL SMOOTH-MUSCLE IS MEDIATED BY AN INCREASE IN CGMP - FURTHER EVIDENCE FOR THE ROLE OF NITRIC-OXIDE. BRITISH JOURNAL OF PHARMACOLOGY. 112:U42-U42. Author weblink.
  • Ward JK; Fox AJ; Barnes PJ; Belvisi MG. (Apr 1994). Inhibition of excitatory non-adrenergic non-cholinergic bronchoconstriction in guinea-pig airways in vitro by activation of an atypical 5-HT receptor. Br J Pharmacol. 111:1095-1102.
  • Takahashi T; Belvisi MG; Barnes PJ. (Apr 1994). Modulation of neurotransmission in guinea-pig airways by galanin and the effect of a new antagonist galantide. Neuropeptides. 26:245-251.
  • Miura M; Belvisi MG; Barnes PJ. (Jan 1994). Modulation of nonadrenergic noncholinergic neural bronchoconstriction by bradykinin in anesthetized guinea pigs in vivo. J Pharmacol Exp Ther. 268:482-486.
  • Belvisi MG; Patacchini R; Barnes PJ; Maggi CA. (Jan 1994). Facilitatory effects of selective agonists for tachykinin receptors on cholinergic neurotransmission: evidence for species differences. Br J Pharmacol. 111:103-110.
  • Barnes PJ; Belvisi MG. (Oct 1993). Nitric oxide and lung disease. Thorax. 48:1034-1043.
  • Ward JK; Belvisi MG; Fox AJ; Miura M; Tadjkarimi S; Yacoub MH; Barnes PJ. (Aug 1993). Modulation of cholinergic neural bronchoconstriction by endogenous nitric oxide and vasoactive intestinal peptide in human airways in vitro. J Clin Invest. 92:736-742. DOI.
  • MIURA M; BELVISI MG; WARD JK; BARNES PJ. (1 Apr 1993). ROLE OF CA2+-ACTIVATED K+ CHANNELS IN OPIOID-INDUCED PREJUNCTIONAL MODULATION OF AIRWAY SENSORY NERVES. AMERICAN REVIEW OF RESPIRATORY DISEASE. 147:A815-A815. Author weblink.
  • BELVISI MG; WARD JK; PATEL HJ; TADJKARIMI S; YACOUB MH; BARNES PJ. (1 Apr 1993). MU-OPIOIDS INHIBIT ELECTRICALLY EVOKED ACETYLCHOLINE-RELEASE IN HUMAN AND GUINEA-PIG TRACHEA. AMERICAN REVIEW OF RESPIRATORY DISEASE. 147:A502-A502. Author weblink.
  • BELVISI MG; WARD JK; TADJKARIMI S; YACOUB MH; BARNES PJ. (1 Apr 1993). INHIBITORY NANC NERVES IN HUMAN AIRWAYS - DIFFERENCES IN DISEASE AND AFTER EXTRINSIC DENERVATION. AMERICAN REVIEW OF RESPIRATORY DISEASE. 147:A286-A286. Author weblink.
  • BELVISI MG; PATACCHINI R; BARNES PJ; MAGGI CA. (1 Apr 1993). FACILITATORY EFFECTS OF SELECTIVE AGONISTS FOR TACHYKININ RECEPTORS ON CHOLINERGIC NEUROTRANSMISSION. AMERICAN REVIEW OF RESPIRATORY DISEASE. 147:A502-A502. Author weblink.
  • WARD JK; FOX AJ; BARNES PJ; BELVISI MG. (1 Apr 1993). 5-HYDROXYTRYPTAMINE INHIBITS EXCITATORY NONADRENERGIC NONCHOLINERGIC NEUROTRANSMISSION IN GUINEA-PIG AIRWAYS. AMERICAN REVIEW OF RESPIRATORY DISEASE. 147:A814-A814. Author weblink.
  • WARD JK; FOX AJ; MIURA M; TADJKARIMI S; YACOUB MY; BARNES PJ; BELVISI MG. (1 Apr 1993). NITRIC-OXIDE MODULATES CHOLINERGIC NEUROTRANSMISSION IN HUMAN AIRWAYS. AMERICAN REVIEW OF RESPIRATORY DISEASE. 147:A515-A515. Author weblink.
  • Verleden GM; Belvisi MG; Rabe KF; Miura M; Barnes PJ. (Mar 1993). Beta 2-adrenoceptor agonists inhibit NANC neural bronchoconstrictor responses in vitro. J Appl Physiol. 74:1195-1199.
  • Miura M; Belvisi MG; Ward JK; Tadjkarimi S; Yacoub MH; Barnes PJ. (Mar 1993). Bronchodilating effects of the novel potassium channel opener HOE 234 in human airways in vitro. Br J Clin Pharmacol. 35:318-320.
  • Belvisi MG; Miura M; Stretton D; Barnes PJ. (26 Jan 1993). Endogenous vasoactive intestinal peptide and nitric oxide modulate cholinergic neurotransmission in guinea-pig trachea. Eur J Pharmacol. 231:97-102.
  • Belvisi MG; Stretton CD; Miura M; Verleden GM; Tadjkarimi S; Yacoub MH; Barnes PJ. (Dec 1992). Inhibitory NANC nerves in human tracheal smooth muscle: a quest for the neurotransmitter. J Appl Physiol. 73:2505-2510.
  • GIEMBYCZ MA; BELVISI MG; MIURA M; PERKINS RS; KELLY J; TADJKARIMI S; YACOUB MH; BARNES PJ. (1 Oct 1992). SOLUBLE CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE ISOENZYMES FROM HUMAN TRACHEAL SMOOTH-MUSCLE. BRITISH JOURNAL OF PHARMACOLOGY. 107:P52-P52. Author weblink.
  • BELVISI MG; MIURA M; PETERS MJ; WARD JK; TADJKARIMI S; YACOUB MH; GIEMBYCZ MA; BARNES PJ. (1 Oct 1992). EFFECT OF ISOENZYME-SELECTIVE CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS ON HUMAN TRACHEAL SMOOTH-MUSCLE TONE. BRITISH JOURNAL OF PHARMACOLOGY. 107:P53-P53. Author weblink.
  • Miura M; Belvisi MG; Barnes PJ. (Oct 1992). Effect of bradykinin on airway neural responses in vitro. J Appl Physiol. 73:1537-1541.
  • WARD JK; FOX AJ; MIURA M; TADJKARIMI S; YACOUB MH; BARNES PJ; BELVISI MG. (1 Oct 1992). MODULATION OF CHOLINERGIC NEUROTRANSMISSION BY NITRIC-OXIDE IN HUMAN AIRWAY SMOOTH-MUSCLE. BRITISH JOURNAL OF PHARMACOLOGY. 107:P85-P85. Author weblink.
  • Miura M; Belvisi MG; Stretton CD; Yacoub MH; Barnes PJ. (Sep 1992). Role of K+ channels in the modulation of cholinergic neural responses in guinea-pig and human airways. J Physiol. 455:1-15.
  • Miura M; Belvisi MG; Stretton CD; Yacoub MH; Barnes PJ. (Jul 1992). Role of potassium channels in bronchodilator responses in human airways. Am Rev Respir Dis. 146:132-136.
  • Belvisi MG; Miura M; Stretton D; Barnes PJ. (14 May 1992). Capsazepine as a selective antagonist of capsaicin-induced activation of C-fibres in guinea-pig bronchi. Eur J Pharmacol. 215:341-344.
  • Belvisi MG; Stretton CD; Verleden GM; Ledingham SJ; Yacoub MH; Barnes PJ. (Mar 1992). Inhibition of cholinergic neurotransmission in human airways by opioids. J Appl Physiol. 72:1096-1100.
  • Stretton D; Belvisi MG; Barnes PJ. (Mar 1992). The effect of sensory nerve depletion on cholinergic neurotransmission in guinea pig airways. J Pharmacol Exp Ther. 260:1073-1080.
  • Stretton D; Miura M; Belvisi MG; Barnes PJ. (15 Feb 1992). Calcium-activated potassium channels mediate prejunctional inhibition of peripheral sensory nerves. Proc Natl Acad Sci U S A. 89:1325-1329.
  • Belvisi MG; Stretton CD; Yacoub M; Barnes PJ. (14 Jan 1992). Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans. Eur J Pharmacol. 210:221-222.
  • Barnes PJ; Baraniuk JN; Belvisi MG. (Dec 1991). Neuropeptides in the respiratory tract. Part II. Am Rev Respir Dis. 144:1391-1399.
  • BARNES PJ; BARANIUK JN; BELVISI MG. (1 Dec 1991). NEUROPEPTIDES IN THE RESPIRATORY-TRACT .2. AMERICAN REVIEW OF RESPIRATORY DISEASE. 144:1391-1399. Author weblink.
  • HAMID Q; BELVISI MG; STRETTON D; ROHDE J; HARMAR AJ; BARNES PJ. (1 Nov 1991). LOCALIZATION OF BETA-PRE-PROTACHYKININ MESSENGER-RNA IN NODOSE GANGLION. NEUROPEPTIDES. 20:145-150. Author weblink DOI.
  • Barnes PJ; Baraniuk JN; Belvisi MG. (Nov 1991). Neuropeptides in the respiratory tract. Part I. Am Rev Respir Dis. 144:1187-1198.
  • BARNES PJ; BARANIUK JN; BELVISI MG. (1 Nov 1991). NEUROPEPTIDES IN THE RESPIRATORY-TRACT .1. AMERICAN REVIEW OF RESPIRATORY DISEASE. 144:1187-1198. Author weblink.
  • Hamid Q; Belvisi MG; Stretton D; Rohde J; Harmar AJ; Barnes PJ. (Nov 1991). Localization of beta pre-protachykinin mRNA in nodose ganglion. Neuropeptides. 20:145-150.
  • Belvisi MG; Stretton CD; Barnes PJ. (1 Jul 1991). Bombesin-induced bronchoconstriction in the guinea pig: mode of action. J Pharmacol Exp Ther. 258:36-41.
  • Belvisi MG; Stretton D; Barnes PJ. (6 Jun 1991). Nitric oxide as an endogenous modulator of cholinergic neurotransmission in guinea-pig airways. Eur J Pharmacol. 198:219-221.
  • Stretton CD; Belvisi MG; Barnes PJ. (Mar 1991). Modulation of neural bronchoconstrictor responses in the guinea pig respiratory tract by vasoactive intestinal peptide. Neuropeptides. 18:149-157.
  • Verleden GM; Belvisi MG; Stretton CD; Barnes PJ. (Jan 1991). Nedocromil sodium modulates nonadrenergic, noncholinergic bronchoconstrictor nerves in guinea pig airways in vitro. Am Rev Respir Dis. 143:114-118.
  • Stretton CD; Belvisi MG; Barnes PJ. (Dec 1990). Neuropeptide Y modulates non-adrenergic, non-cholinergic neural bronchoconstriction in vivo and in vitro. Neuropeptides. 17:163-170.
  • Stretton CD; Mak JC; Belvisi MG; Yacoub MH; Barnes PJ. (Nov 1990). Cholinergic control of human airways in vitro following extrinsic denervation of the human respiratory tract by heart-lung transplantation. Am Rev Respir Dis. 142:1030-1033.
  • Stretton CD; Belvisi MG; Barnes PJ. (10 Aug 1990). Sensory nerve depletion potentiates inhibitory non-adrenergic, non-cholinergic nerves in guinea-pig airways. Eur J Pharmacol. 184:333-337.
  • Barnes PJ; Belvisi MG; Rogers DF. (May 1990). Modulation of neurogenic inflammation: novel approaches to inflammatory disease. Trends Pharmacol Sci. 11:185-189.
  • Belvisi MG; Stretton CD; Barnes PJ. (May 1990). Modulation of cholinergic neurotransmission in guinea-pig airways by opioids. Br J Pharmacol. 100:131-137.
  • Belvisi MG; Barnes PJ; Rogers DF. (May 1990). Neurogenic inflammation in the airways: characterisation of electrical parameters for vagus nerve stimulation in the guinea pig. J Neurosci Methods. 32:159-167.
  • Ichinose M; Belvisi MG; Barnes PJ. (May 1990). Bradykinin-induced bronchoconstriction in guinea pig in vivo: role of neural mechanisms. J Pharmacol Exp Ther. 253:594-599.
  • Evans TW; Rogers DF; Belvisi MG; Rohde JA; Chung KF; Barnes PJ. (Mar 1990). Endotoxin-induced plasma exudation in guinea-pig airways in vivo and the effect of neutrophil depletion. Eur Respir J. 3:299-303.
  • Ichinose M; Belvisi MG; Barnes PJ. (Jan 1990). Histamine H3-receptors inhibit neurogenic microvascular leakage in airways. J Appl Physiol. 68:21-25.
  • Stretton CD; Belvisi MG; Barnes PJ. (Dec 1989). The effect of sensory nerve depletion on cholinergic neurotransmission in guinea-pig airways. Br J Pharmacol. 98 Suppl:782P.
  • Stretton CD; Belvisi MG; Barnes PJ. (Dec 1989). Neuropeptide Y modulates non-adrenergic, non-cholinergic neural bronchoconstriction in vivo and in vitro. Br J Pharmacol. 98 Suppl:781P.
  • Stretton CD; Belvisi MG; Barnes PJ. (Dec 1989). Sensory nerve depletion potentiates non-adrenergic, non-cholinergic inhibitory nerves in guinea-pig trachea. Br J Pharmacol. 98 Suppl:780P.
  • Belvisi MG; Ichinose M; Barnes PJ. (Aug 1989). Modulation of non-adrenergic, non-cholinergic neural bronchoconstriction in guinea-pig airways via GABAB-receptors. Br J Pharmacol. 97:1225-1231.
  • Belvisi MG; Rogers DF; Barnes PJ. (Jan 1989). Neurogenic plasma extravasation: inhibition by morphine in guinea pig airways in vivo. J Appl Physiol. 66:268-272.
  • Rogers DF; Belvisi MG; Aursudkij B; Evans TW; Barnes PJ. (Dec 1988). Effects and interactions of sensory neuropeptides on airway microvascular leakage in guinea-pigs. Br J Pharmacol. 95:1109-1116.
  • Belvisi MG; Chung KF; Jackson DM; Barnes PJ. (Oct 1988). Opioid modulation of non-cholinergic neural bronchoconstriction in guinea-pig in vivo. Br J Pharmacol. 95:413-418.
  • AURSUDKIJ B; BARNES PJ; BELVISI MG; DIJK S; EVANS TW; ROGERS DF. (1 Apr 1988). EFFECT OF SUBSTANCE-P, NEUROKININS AND CALCITONIN GENE-RELATED PEPTIDE ON MICROVASCULAR PERMEABILITY IN GUINEA-PIG AIRWAYS. JOURNAL OF PHYSIOLOGY-LONDON. 398:P51-P51. Author weblink.
  • Stevenson CS; Belvisi MG. Preclinical animal models of asthma and chronic obstructive pulmonary disease. Expert Review of Respiratory Medicine. In Press.

Chapters in books

  • Brown TJ; Belvisi MG; Foster ML. Dissociated steroids. 98-101. (2001).

Conferences

  • Khalid S; Dockry R; Holt K; Sumner H; Valdramidou D; Birrell MA; Belvisi MG; Woodcock A; et alSmith JA. COUGH RESPONSES TO TUSSIVE AGENTS IN HEALTH AND DISEASE. Winter Meeting of the British-Thoracic-Society, 7 Dec 2011 - 9 Dec 2011. 66:A64-A64. B M J PUBLISHING GROUP (1 Dec 2011). Author weblink DOI.
  • Belvisi MG. Preclinical assessment of novel therapeutics on the cough reflex: Cannabinoid agonists as potential antitussives. 1st American Cough Conference. 186:S66-S69. (Jan 2008).
  • Patel HJ; Birrell MA; Crispino N; Hele DJ; Yacoub MH; Venkatesan P; Barnes PJ; Belvisi MG. The effect of a cannabinoid (CB2) agonist on activation of airway sensory nerves in vitro and the cough reflex. Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, 7 Jan 2003 - 10 Jan 2003. 138:U37-U37. NATURE PUBLISHING GROUP (1 Apr 2003). Author weblink.
  • Birrell MA; Patel HJ; McCluskie K; Wong S; Leonard T; Yacoub MH; Belvisi MG. Peroxisome proliferator-activated receptor gamma (PPAR gamma) agonists: A possible therapy for chronic obstructive pulmonary disease (COPD). Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section. 138:U38-U38. (Apr 2003).
  • Usmani OS; Patel HJ; Belvisi MG; Barnes PJ. Chocolate, chilli pepper, and cough. Winter Meeting of the British-Thoracic-Society, 4 Dec 2002 - 6 Dec 2002. 57. BRITISH MED JOURNAL PUBL GROUP (1 Dec 2002). Author weblink.
  • BELVISI MG. EFFECTS OF NEUROPEPTIDES ON NEUROTRANSMISSION IN THE AIRWAYS. Conference on Neuropeptides in Respiratory Medicine. 4:477-500. (1994).
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