Dr Michael Emerson

Publications


Journals

  • Kilkenny C; Browne WJ; Cuthill IC; Emerson M; Altman DG. (1 Apr 2012). Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. OSTEOARTHRITIS AND CARTILAGE. 20:256-260. Author weblink DOI.
  • Solomon A; Jones S; Sanz-Rosa D; Holbrook L-M; Moore C; Neyses L; Emerson M. (23 Nov 2010). The Plasma Membrane Calcium ATPase Regulates Calcium Homeostasis, Function and Negative Signalling Events in Platelets. CIRCULATION. 122. Author weblink.
  • Kilkenny C; Browne WJ; Cuthill IC; Emerson M; Altman DG. (1 Mar 2012). Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research. VETERINARY CLINICAL PATHOLOGY. 41:27-31. DOI.
  • Holbrook L; Moore C; Sanz-Rosa D; Solomon A; Emerson M. (Mar 2012). A NOD/SCID mouse model for the assessment of human platelet aggregation in vivo. J Thromb Haemost. 10:490-492. DOI.
  • Moore C; Emerson M. (2012). Assessment of platelet aggregation responses in vivo in the mouse. Methods Mol Biol. 788:21-28. DOI.
  • Mohamed TM; Oceandy D; Zi M; Prehar S; Alatwi N; Wang Y; Shaheen MA; Abou-Leisa R; et alSchelcher C; Hegab Z; Baudoin F; Emerson M; Mamas M; Di Benedetto G; Zaccolo M; Lei M; Cartwright EJ; Neyses L. (2 Dec 2011). Plasma membrane calcium pump (PMCA4)-neuronal nitric-oxide synthase complex regulates cardiac contractility through modulation of a compartmentalized cyclic nucleotide microdomain. J Biol Chem. 286:41520-41529. DOI.
  • Armstrong PC; Kirkby NS; Zain ZN; Emerson M; Mitchell JA; Warner TD. (2011). Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse. PLoS One. 6:e20062. DOI.
  • Kilkenny C; Browne W; Cuthill IC; Emerson M; Altman DG. (1 Apr 2011). Animal research: reporting in vivo experiments-The ARRIVE Guidelines. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 31:991-993. Author weblink DOI.
  • Moore C; Sanz-Rosa D; Emerson M. (25 Jan 2011). Distinct role and location of the endothelial isoform of nitric oxide synthase in regulating platelet aggregation in males and females in vivo. Eur J Pharmacol. 651:152-158. DOI.
  • Jones S; Solomon A; Sanz-Rosa D; Moore C; Holbrook L; Cartwright EJ; Neyses L; Emerson M. (Dec 2010). The plasma membrane calcium ATPase modulates calcium homeostasis, intracellular signaling events and function in platelets. J Thromb Haemost. 8:2766-2774. DOI.
  • Emerson M. (Oct 2010). Refinement, reduction and replacement approaches to in vivo cardiovascular research. Br J Pharmacol. 161:749-754. DOI.
  • Kilkenny C; Browne W; Cuthill IC; Emerson M; Altmans DG. (1 Jul 2010). Animal Research: Reporting In Vivo Experiments: The ARRIVE Guidelines. JOURNAL OF GENE MEDICINE. 12:561-563. DOI.
  • Holton M; Mohamed TMA; Oceandy D; Wang W; Lamas S; Emerson M; Neyses L; Armesilla AL. (1 Aug 2010). Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells. CARDIOVASCULAR RESEARCH. 87:440-448. DOI.
  • Kilkenny C; Browne W; Cuthill IC; Emerson M; Altman DG. (1 Aug 2010). Animal research: Reporting in vivo experiments: The ARRIVE guidelines. BRITISH JOURNAL OF PHARMACOLOGY. 160:1577-1579. Author weblink DOI.
  • Kilkenny C; Browne WJ; Cuthill IC; Emerson M; Altman DG. (1 Jun 2010). Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research. PLOS BIOLOGY. 8. DOI.
  • Emerson M. (1 Jun 2010). Kv1.3: the perfect opening of the platelet voltage gate. J Physiol. 588:1809. DOI.
  • Moore C; Tymvios C; Emerson M. (Aug 2010). Functional regulation of vascular and platelet activity during thrombosis by nitric oxide and endothelial nitric oxide synthase. Thromb Haemost. 104:342-349. DOI.
  • Tymvios C; Moore C; Jones S; Solomon A; Sanz-Rosa D; Emerson M. (1 Dec 2009). Platelet aggregation responses are critically regulated in vivo by endogenous nitric oxide but not by endothelial nitric oxide synthase. BRITISH JOURNAL OF PHARMACOLOGY. 158:1735-1742. Author weblink DOI.
  • Izzard AS; Emerson M; Prehar S; Neyses L; Trainer P; List EO; Kopchick JJ; Heagerty AM. (Oct 2009). The cardiovascular phenotype of a mouse model of acromegaly. Growth Horm IGF Res. 19:413-419. DOI.
  • Solomon A; Jones S; Tymvios C; Moore C; Emerson M. (1 Aug 2008). The functional role of the plasma membrane calcium ATPase (PMCA) in platelets. FUNDAMENTAL & CLINICAL PHARMACOLOGY. 22:73-73. Author weblink.
  • Tymvios C; Moore C; Jones S; Solomon A; Emerson M. (1 Aug 2008). Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetised mice. FUNDAMENTAL & CLINICAL PHARMACOLOGY. 22:31-31. Author weblink.
  • Tymvios C; Jones S; Moore C; Pitchford SC; Page CP; Emerson M. (Feb 2008). Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse. Thromb Haemost. 99:435-440. DOI.
  • Jones S; Tucker KL; Sage T; Kaiser WJ; Barrett NE; Lowry PJ; Zimmer A; Hunt SP; et alEmerson M; Gibbins JM. (15 Jan 2008). Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation. BLOOD. 111:605-612. Author weblink DOI.
  • The Eumorphia Consortium. (2005). EMPReSS: standardized phenotype screens for functional annotation of the mouse genome. Nat Genet. 11, 37:1155-1156. Author weblink.
  • Nadif-Savey R; Cartwright EJ; Emerson M; Guo C; Mayer U; Neyses L. (1 Jun 2007). Abnormal electrical function of the heart caused by loss of integrin alpha 7 gene. EUROPEAN JOURNAL OF HEART FAILURE. 6:43-43. Author weblink DOI.
  • Oceandy D; Cartwright EJ; Emerson M; Prehar S; Baudoin FM; Zi M; Alatwi N; Venetucci L; et alSchuh K; Williams JC; Armesilla AL; Neyses L. (30 Jan 2007). Neuronal nitric oxide synthase signaling in the heart is regulated by the sarcolemmal calcium pump 4b. Circulation. 115:483-492. DOI.
  • Williams JC; Armesilla AL; Mohamed TM; Hagarty CL; McIntyre FH; Schomburg S; Zaki AO; Oceandy D; et alCartwright EJ; Buch MH; Emerson M; Neyses L. (18 Aug 2006). The sarcolemmal calcium pump, alpha-1 syntrophin, and neuronal nitric-oxide synthase are parts of a macromolecular protein complex. J Biol Chem. 281:23341-23348. DOI.
  • Guo C; Willem M; Werner A; Raivich G; Emerson M; Neyses L; Mayer U. (15 Mar 2006). Absence of alpha 7 integrin in dystrophin-deficient mice causes a myopathy similar to Duchenne muscular dystrophy. Hum Mol Genet. 15:989-998. DOI.
  • Buch MH; Pickard A; Rodriguez A; Gillies S; Maass AH; Emerson M; Cartwright EJ; Williams JC; et alOceandy D; Redondo JM; Neyses L; Armesilla AL. (19 Aug 2005). The sarcolemmal calcium pump inhibits the calcineurin/nuclear factor of activated T-cell pathway via interaction with the calcineurin A catalytic subunit. J Biol Chem. 280:29479-29487. DOI.
  • Nadif-Savey R; Ismayilova N; Neyses L; Mayer U; Emerson M. (1 Dec 2004). Absence of alpha 7-integrin leads to progressive structural changes in the heart. HEART. 90. Author weblink.
  • Armesilla AL; Williams JC; Buch MH; Pickard A; Emerson M; Cartwright EJ; Oceandy D; Vos MD; et alGillies S; Clark GJ; Neyses L. (23 Jul 2004). Novel functional interaction between the plasma membrane Ca2+ pump 4b and the proapoptotic tumor suppressor Ras-associated factor 1 (RASSF1). J Biol Chem. 279:31318-31328. DOI.
  • Schuh K; Cartwright EJ; Jankevics E; Bundschu K; Liebermann J; Williams JC; Armesilla AL; Emerson M; et alOceandy D; Knobeloch KP; Neyses L. (2 Jul 2004). Plasma membrane Ca2+ ATPase 4 is required for sperm motility and male fertility. JOURNAL OF BIOLOGICAL CHEMISTRY. 279:28220-28226. Author weblink DOI.
  • Emerson M; Renwick L; Tate S; Rhind S; Milne E; Painter H; Boyd AC; McLachlan G; et alGriesenbach U; Cheng SH; Gill DR; Hyde SC; Baker A; Alton EW; Porteous DJ; Collie DDS. (1 Oct 2003). Transfection efficiency and toxicity following delivery of naked plasmid DNA and cationic lipid-DNA complexes to ovine lung segments. MOLECULAR THERAPY. 8:646-653. Author weblink DOI.

Conferences

  • Shaheen MA; Mohamed TMA; Zi M; Prehar S; Alatwi N; Hegab Z; Baudoin F; Emerson M; et alOceandy D; Cartwright EJ; Neyses L. DIFFERENTIAL ROLES OF THE PLASMA MEMBRANE CALCIUM PUMP ISOFORMS 1 AND 4 IN MODULATING CARDIAC CONTRACTILITY. Annual Conference and Exhibition of the British-Cardiovascular-Society, 7 Jun 2010 - 9 Jun 2010. 96:A10-A10. B M J PUBLISHING GROUP (1 Jun 2010). Author weblink DOI.
  • Shaheen MA; Mohamed TM; Zi M; Prehar S; Alatwi N; Hegab Z; Baudoin F; Emerson M; et alOceandy D; Cartwright EJ; Neyses L. Cardiac Contractility is Differentially Modulated by Isoforms 1 and 4 of the Plasma Membrane Calcium Pump. 82nd Scientific Session of the American-Heart-Association, 14 Nov 2009 - 18 Nov 2009. 120:S870-S871. LIPPINCOTT WILLIAMS & WILKINS (3 Nov 2009).
  • Nadif R; Emerson M; Mohamed TM; Oceandy D; Pfeufer A; Sanna S; Arking DE; Mayer U; et alNeyses L; Cartwright E. Integrin Alpha7, a Novel Determinant of QT Duration and Lethal Ventricular Arrhythmias in Mouse and Man. 82nd Scientific Session of the American-Heart-Association, 14 Nov 2009 - 18 Nov 2009. 120:S631-S632. LIPPINCOTT WILLIAMS & WILKINS (3 Nov 2009).
  • Nadif R; Emerson M; Mayer U; Neyses L; Cartwright E. Deletion Of Integrin Alpha7 Leads To Altered Cardiac Conduction And Sudden Death Associated With Connexin43 Downregulation. 81st Annual Scientific Session of the American-Heart-Association, 8 Nov 2008 - 12 Nov 2008. 118:S494-S494. LIPPINCOTT WILLIAMS & WILKINS (28 Oct 2008). Author weblink.
  • Nadif R; Emerson M; Mayer U; Neyses L; Cartwright EJ. Abnormal electrical function and hypertrophy of the heart caused by loss of integrin alpha 7. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A55-A55. (Jul 2008).
  • Emerson M; Cartwright EJ; Prehar S; Zi M; Baudoin F; Kuppitayanant P; Eisner D; Trafford A; et alNeyses L. The sarcolemmal calcium pump regulates in vivo contractile function in the heart. 77th Scientific Meeting of the American-Heart-Association. 110:130-130. (26 Oct 2004).
  • Nadif-Savey R; Emerson M; Prehar S; Mayer U; Neyses L. Integrin alpha 7 is essential for normal heart structure. 25th Annual Scientific Session of the European Section of the International-Society-Heart-Research. 38:1049-1049. (Jun 2005).
  • Zi M; Prehar S; Cartwright EJ; Emerson M; Neyses L. The sarcolemmal calcium pump modulates beta-adrenergic hypertrophic signalling. 28th Annual International-Society-for-Heart-Research North American Section Meeting. 40:1003-1004. (Jun 2006).
  • Nadif-Savey R; Emerson M; Cartwright EJ; Mayer U; Neyses L; Cardiovasc Mole Med Unit. Alpha 7 integrin is a major determinant of heart shape and function. World Congress of Cardiology. 27:954-954. (Aug 2006).
  • Zi M; Oceandy D; Cartwright EJ; Emerson M; Neyses L. Modulation of diastolic function in cardiac hypertrophy by a novel pathway involving the sarcolemmal calcium pump. World Congress of Cardiology. 27:32-32. (Aug 2006).
  • Oceandy D; Cartwright EJ; Prehar S; Zi M; Alatwi N; Emerson M; Neyses L. The sarcolemmal calcium pump: A novel mediator of cellular signalling and contractile function in the heart. World Congress of Cardiology, 2 Sep 2006 - 6 Sep 2006. 27:150-150. OXFORD UNIV PRESS (1 Aug 2006). Author weblink.
  • Tymvios C; Paul W; Page CP; Emerson M. A novel technique for assessing physiological platelet function in the mouse. 28th Annual International-Society-for-Heart-Research North American Section Meeting, 13 Jun 2006 - 16 Jun 2006. 40:922-922. ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD (1 Jun 2006). Author weblink DOI.
  • Nadif-Savey R; Emerson M; Cartwright EJ; Mayer U; Neyses L. Alpha 7 integrin is essential for normal heart shape and function. 28th Annual International-Society-for-Heart-Research North American Section Meeting, 13 Jun 2006 - 16 Jun 2006. 40:1003-1003. ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD (1 Jun 2006). Author weblink DOI.
  • Izzard AS; Emerson M; Prehar S; Neyses L; Trainer P; Coshigano KT; Kopchick JJ; Heagerty AM. The cardiovascular phenotytpe of a mouse model of acromegaly. 16th European Meeting on Hypertension, 12 Jun 2006 - 15 Jun 2006. 24:S362-S362. LIPPINCOTT WILLIAMS & WILKINS (1 Jun 2006). Author weblink.
  • Nadif-Savey R; Emerson M; Prehar S; Ismayilova N; Mayer U; Neyses L. Integrin alpha 7 is required for normal heart structure. Annual Autumn Meeting of the British-Society-for-Cardiovascular-Research, 15 Sep 2005 - 16 Sep 2005. 92. B M J PUBLISHING GROUP (1 Feb 2006). Author weblink.
  • Oceandy D; Cartwright EJ; Emerson M; Prehar S; Baudoin F; Zi M; Neyses L. The plasma membrane calcium ATPase regulates cardiac contractility and beta adrenergic signalling depending on PDZ binding. ESC Congress 2004, 28 Aug 2004 - 1 Sep 2004. 25:636-636. W B SAUNDERS CO LTD (1 Aug 2004). Author weblink.
  • Renwick L; Tate S; Painter H; Gill D; Griesenbach U; Boyd C; Emerson M; Cheng S; et alCollie D. Biological efficacy and toxicity of naked plasmid DNA and cationic liposome-DNA complexes in ovine lung. 6th Annual Meeting of the American-Society-of-Gene-Therapy, 4 Jun 2003 - 8 Jun 2003. 7:S441-S441. ACADEMIC PRESS INC ELSEVIER SCIENCE (1 May 2003). Author weblink.
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