Professor Michael Levin

Publications


Journals

  • Renner P; Roger T; Bochud P-Y; Sprong T; Sweep FCGJ; Bochud M; Faust SN; Haralambous E; et alBetts H; Chanson A-L; Reymond MK; Mermel E; Erard V; van Deuren M; Read RC; Levin M; Calandra T. (1 Feb 2012). A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease. FASEB JOURNAL. 26:907-916. Author weblink DOI.
  • Breunis WB; Davila S; Shimizu C; Oharaseki T; Takahashi K; van Houdt M; Khor CC; Wright VJ; et alLevin M; Burns JC; Burgner D; Hibberd ML; Kuijpers TW; International Kawasaki Disease Genetics Consortium. (Jan 2012). Disruption of vascular homeostasis in patients with Kawasaki disease: involvement of vascular endothelial growth factor and angiopoietins. Arthritis Rheum. 64:306-315. DOI.
  • Brent AJ; Mugo D; Musyimi R; Mutiso A; Morpeth S; Levin M; Scott JAG. (1 Dec 2011). Performance of the MGIT TBc Identification Test and Meta-Analysis of MPT64 Assays for Identification of the Mycobacterium tuberculosis Complex in Liquid Culture. JOURNAL OF CLINICAL MICROBIOLOGY. 49:4343-4346. DOI.
  • Khor CC; Davila S; Breunis WB; Lee YC; Shimizu C; Wright VJ; Yeung RS; Tan DE; et alSim KS; Wang JJ; Wong TY; Pang J; Mitchell P; Cimaz R; Dahdah N; Cheung YF; Huang GY; Yang W; Park IS; Lee JK; Wu JY; Levin M; Burns JC; Burgner D; Kuijpers TW; Hibberd ML; Hong Kong–Shanghai Kawasaki Disease Genetics Consortium; Korean Kawasaki Disease Genetics Consortium; Taiwan Kawasaki Disease Genetics Consortium; International Kawasaki Disease Genetics Consortium; US Kawasaki Disease Genetics Consortium; Blue Mountains Eye Study. (Dec 2011). Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet. 43:1241-1246. DOI.
  • Eleftherohorinou H; Hoggart CJ; Wright VJ; Levin M; Coin LJM. (1 Sep 2011). Pathway-driven gene stability selection of two rheumatoid arthritis GWAS identifies and validates new susceptibility genes in receptor mediated signalling pathways. HUMAN MOLECULAR GENETICS. 20:3494-3506. Author weblink DOI.
  • Pathan N; Burmester M; Adamovic T; Berk M; Ng KW; Betts H; Macrae D; Waddell S; et alPaul-Clark M; Nuamah R; Mein C; Levin M; Montana G; Mitchell JA. (1 Dec 2011). Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease. Am J Respir Crit Care Med. 184:1261-1269. DOI.
  • Khor CC; Davila S; Shimizu C; Sheng S; Matsubara T; Suzuki Y; Newburger JW; Baker A; et alBurgner D; Breunis W; Kuijpers T; Wright VJ; Levin M; Hibberd ML; Burns JC; US and International Kawasaki Disease Genetics Consortia. (Jul 2011). Genome-wide linkage and association mapping identify susceptibility alleles in ABCC4 for Kawasaki disease. J Med Genet. 48:467-472. DOI.
  • Maitland K; Kiguli S; Opoka RO; Engoru C; Olupot-Olupot P; Akech SO; Nyeko R; Mtove G; et alReyburn H; Lang T; Brent B; Evans JA; Tibenderana JK; Crawley J; Russell EC; Levin M; Babiker AG; Gibb DM; FEAST Trial Group. (30 Jun 2011). Mortality after fluid bolus in African children with severe infection. N Engl J Med. 364:2483-2495. DOI.
  • Pathan N; Franklin JL; Eleftherohorinou H; Wright VJ; Hemingway CA; Waddell SJ; Griffiths M; Dennis JL; et alRelman DA; Harding SE; Levin M. (Jul 2011). Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase. Crit Care Med. 39:1692-1711. DOI.
  • Brent AJ; Lakhanpaul M; Thompson M; Collier J; Ray S; Ninis N; Levin M; MacFaul R. (1 Apr 2011). Risk score to stratify children with suspected serious bacterial infection: observational cohort study. ARCHIVES OF DISEASE IN CHILDHOOD. 96:361-U182. Author weblink DOI.
  • Brent AJ; Lakhanpaul M; Ninis N; Levin M; MacFaul R; Thompson M. (1 Apr 2011). Evaluation of temperature-pulse centile charts in identifying serious bacterial illness: observational cohort study. ARCHIVES OF DISEASE IN CHILDHOOD. 96:368-373. Author weblink DOI.
  • Shimizu C; Jain S; Davila S; Hibberd ML; Lin KO; Molkara D; Frazer JR; Sun S; et alBaker AL; Newburger JW; Rowley AH; Shulman ST; Burgner D; Breunis WB; Kuijpers TW; Wright VJ; Levin M; Eleftherohorinou H; Coin L; Popper SJ; Relman DA; Fury W; Lin C; Mellis S; Tremoulet AH; Burns JC. (Feb 2011). Transforming growth factor-beta signaling pathway in patients with Kawasaki disease. Circ Cardiovasc Genet. 4:16-25. DOI.
  • Shimizu C; Matsubara T; Onouchi Y; Jain S; Sun S; Nievergelt CM; Shike H; Brophy VH; et alTakegawa T; Furukawa S; Akagi T; Newburger JW; Baker AL; Burgner D; Hibberd ML; Davila S; Levin M; Mamtani M; He W; Ahuja SK; Burns JC. (Dec 2010). Matrix metalloproteinase haplotypes associated with coronary artery aneurysm formation in patients with Kawasaki disease. J Hum Genet. 55:779-784. DOI.
  • Herberg JA; Jones KD; Paulus S; Gormley S; Muir D; Cooper M; Levin M. (May 2011). Comparison of pandemic and seasonal influenza reveals higher mortality and increased prevalence of shock in children with severe h1n1/09 infection. Pediatr Infect Dis J. 30:438-440. DOI.
  • de Beaucoudrey L; Samarina A; Bustamante J; Cobat A; Boisson-Dupuis S; Feinberg J; Al-Muhsen S; Jannière L; et alRose Y; de Suremain M; Kong XF; Filipe-Santos O; Chapgier A; Picard C; Fischer A; Dogu F; Ikinciogullari A; Tanir G; Al-Hajjar S; Al-Jumaah S; Frayha HH; AlSum Z; Al-Ajaji S; Alangari A; Al-Ghonaium A; Adimi P; Mansouri D; Ben-Mustapha I; Yancoski J; Garty BZ; Rodriguez-Gallego C; Caragol I; Kutukculer N; Kumararatne DS; Patel S; Doffinger R; Exley A; Jeppsson O; Reichenbach J; Nadal D; Boyko Y; Pietrucha B; Anderson S; Levin M; Schandené L; Schepers K; Efira A; Mascart F; Matsuoka M; Sakai T; Siegrist CA; Frecerova K; Blüetters-Sawatzki R; Bernhöft J; Freihorst J; Baumann U; Richter D; Haerynck F; De Baets F; Novelli V; Lammas D; Vermylen C; Tuerlinckx D; Nieuwhof C; Pac M; Haas WH; Müller-Fleckenstein I; Fleckenstein B; Levy J; Raj R; Cohen AC; Lewis DB; Holland SM; Yang KD; Wang X; Wang X; Jiang L; Yang X; Zhu C; Xie Y; Lee PP; Chan KW; Chen TX; Castro G; Natera I; Codoceo A; King A; Bezrodnik L; Di Giovani D; Gaillard MI; de Moraes-Vasconcelos D; Grumach AS; da Silva Duarte AJ; Aldana R; Espinosa-Rosales FJ; Bejaoui M; Bousfiha AA; Baghdadi JE; Ozbek N; Aksu G; Keser M; Somer A; Hatipoglu N; Aydogmus C; Asilsoy S; Camcioglu Y; Gülle S; Ozgur TT; Ozen M; Oleastro M; Bernasconi A; Mamishi S; Parvaneh N; Rosenzweig S; Barbouche R; Pedraza S; Lau YL; Ehlayel MS; Fieschi C; Abel L; Sanal O; Casanova JL. (Nov 2010). Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries. Medicine (Baltimore). 89:381-402. DOI.
  • Davila S; Wright VJ; Khor CC; Sim KS; Binder A; Breunis WB; Inwald D; Nadel S; et alBetts H; Carrol ED; de Groot R; Hermans PW; Hazelzet J; Emonts M; Lim CC; Kuijpers TW; Martinon-Torres F; Salas A; Zenz W; Levin M; Hibberd ML; International Meningococcal Genetics Consortium. (Sep 2010). Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. Nat Genet. 42:772-776. DOI.
  • Waddell SJ; Popper SJ; Rubins KH; Griffiths MJ; Brown PO; Levin M; Relman DA. (22 Mar 2010). Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood Cells. PLOS ONE. 5. DOI.
  • Emonts M; Vermont CL; Houwing-Duistermaat JJ; Haralambous E; Gaast-de Jongh CE; Hazelzet JA; Faust SN; Betts H; et alHermans PW; Levin M; de Groot R; St. Mary's-Imperial College and Erasmus MC-Sophia Children's Hospitals Meningococcal Research Groups. (Jul 2010). Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations. Shock. 34:17-22. DOI.
  • Eleftherohorinou H; Wright V; Hoggart C; Hartikainen AL; Jarvelin MR; Balding D; Coin L; Levin M. (2009). Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases. PLoS One. 4:e8068. DOI.
  • Martineau AR; Leandro AC; Anderson ST; Newton SM; Wilkinson KA; Nicol MP; Pienaar SM; Skolimowska KH; et alRocha MA; Rolla VC; Levin M; Davidson RN; Bremner SA; Griffiths CJ; Eley BS; Bonecini-Almeida MG; Wilkinson RJ. (May 2010). Association between Gc genotype and susceptibility to TB is dependent on vitamin D status. Eur Respir J. 35:1106-1112. DOI.
  • Dissanayeke SR; Levin S; Pienaar S; Wood K; Eley B; Beatty D; Henderson H; Anderson S; et alLevin M. (2009). Polymorphic variation in TIRAP is not associated with susceptibility to childhood TB but may determine susceptibility to TBM in some ethnic groups. PLoS One. 4:e6698. DOI.
  • Wright V; Hibberd M; Levin M. (24 Jun 2009). Genetic polymorphisms in host response to meningococcal infection: The role of susceptibility and severity genes. VACCINE. 27:B90-B102. Author weblink DOI.
  • Burgner D; Davila S; Breunis WB; Ng SB; Li Y; Bonnard C; Ling L; Wright VJ; et alThalamuthu A; Odam M; Shimizu C; Burns JC; Levin M; Kuijpers TW; Hibberd ML. (1 Jan 2009). A Genome-Wide Association Study Identifies Novel and Functionally Related Susceptibility Loci for Kawasaki Disease. PLOS GENETICS. 5. Author weblink DOI.
  • Cathie K; Levin M; Faust SN. (1 Oct 2008). Drug use in acute meninglococcal disease. ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION. 93:151-158. DOI.
  • Allport T; Read L; Nadel S; Levin M. (1 Sep 2008). Critical illness and amputation in meningococcal septicemia: Is life worth saving?. PEDIATRICS. 122:629-632. Author weblink DOI.
  • Callaghan MJ; Buckee C; McCarthy ND; Pavon ABI; Jolley KA; Faust S; Gray SJ; Kaczmarski EB; et alLevin M; Kroll JS; Maiden MCJ; Pollard AJ. (1 Sep 2008). Opa protein repertoires of disease-causing and carried meningococci. JOURNAL OF CLINICAL MICROBIOLOGY. 46:3033-3041. Author weblink DOI.
  • Pulickal AS; Hambleton S; Callaghan MJ; Moore CE; Goulding J; Goodsall A; Baretto R; Lammas DA; et alAnderson ST; Levin M; Pollard AJ. (1 Aug 2008). Biliary cirrhosis in a child with inherited interleukin-12 deficiency. JOURNAL OF TROPICAL PEDIATRICS. 54:269-271. Author weblink DOI.
  • Newton SM; Mackie SL; Martineau AR; Wilkinson KA; Kampmann B; Fisher C; Dutta S; Levin M; et alWilkinson RJ; Pasvol G. (1 Mar 2008). Reduction of chemokine secretion in response to mycobacteria in infliximab-treated patients. CLINICAL AND VACCINE IMMUNOLOGY. 15:506-512. Author weblink DOI.
  • Faust SN; Pollard AJ; Nadel S; Ninis N; Levin M. (1 Feb 2008). Ceftriaxone drug alert: no longer for first line use in meningococcal sepsis. ARCHIVES OF DISEASE IN CHILDHOOD. 93:184-185. Author weblink.
  • Callaghan MJ; Rockett K; Banner C; Haralambous E; Betts H; Faust S; Maiden MCJ; Kroll JS; et alLevin M; Kwiatkowski DP; Pollard AJ. (1 Jan 2008). Haplotypic diversity in human CEACAM genes: effects on susceptibility to meningococcal disease. GENES AND IMMUNITY. 9:30-37. Author weblink DOI.
  • Pollard AJ; Nadel S; Ninis N; Faust SN; Levin M. (1 Apr 2007). Emergency management of meningococcal disease: eight years on. ARCHIVES OF DISEASE IN CHILDHOOD. 92:283-286. Author weblink DOI.
  • Maitland K; Akech S; Gwer S; Idro R; Fegan G; Eziefula AC; Levin M; Newton CRJC. (9 Feb 2007). Phase III trials required to resolve clinical equipoise over optimal fluid management in children with severe malaria. PLOS CLINICAL TRIALS. 2. Author weblink DOI.
  • Hodgetts A; Levin M; Kroll JS; Langford PR. (Feb 2007). Biomarker discovery in infectious diseases using SELDI. Future Microbiol. 2:35-49. DOI.
  • Akech S; Gwer S; Richard I; Fegan G; Eziefula AC; Newton CRJC; Levin M; Maitland K. (15 Sep 2006). Volume expansion with albumin compared to gelofusine in children with severe malaria: Results of a controlled trial. PLOS CLINICAL TRIALS. 1. Author weblink DOI.
  • Inwald DP; Faust SN; Lister P; Peters MJ; Levin M; Heyderman R; Klein NJ. (Sep 2006). Platelet and soluble CD40L in meningococcal sepsis. Intensive Care Med. 32:1432-1437. DOI.
  • Levin M. (Jul 2006). Anti-interferon auto-antibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS Med. 3:e292. DOI.
  • Harnden A; Ninis N; Thompson M; Perera R; Levin M; Mant D; Mayon-White R. (3 Jun 2006). Parenteral penicillin for children with meningococcal disease before hospital admission: case-control study. BRITISH MEDICAL JOURNAL. 332:1295-1297. Author weblink DOI.
  • Kelleher P; Goodsall A; Mulgirigama A; Kunst H; Henderson DC; Wilson R; Newman-Taylor A; Levin M. (Jun 2006). Interferon-gamma therapy in two patients with progressive chronic pulmonary aspergillosis. Eur Respir J. 27:1307-1310. DOI.
  • Anderson ST; Williams AJ; Brown JR; Newton SM; Simsova M; Nicol MP; Sebo P; Levin M; et alWilkinson RJ; Wilkinson KA. (1 May 2006). Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing. Am J Respir Crit Care Med. 173:1038-1042. DOI.
  • Kampmann B; Tena-Coki GN; Nicol MP; Levin M; Eley B. (24 Apr 2006). Reconstitution of antimycobacterial immune responses in HIV-infected children receiving HAART. AIDS. 20:1011-1018. DOI.
  • Thompson MJ; Ninis N; Perera R; Mayon-White R; Phillips C; Bailey L; Harnden A; Mant D; et alLevin M. (4 Feb 2006). Clinical recognition of meningococcal disease in children and adolescents. Lancet. 367(9508):397-403.
  • Haralambous E; Dolly SO; Hibberd ML; Litt DJ; Udalova IA; O'dwyer C; Langford PR; Simon Kroll J; et alLevin M. (2006). Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients. Scand J Infect Dis. 38:764-771. DOI.
  • Kampmann B; Hemingway C; Stephens A; Davidson R; Goodsall A; Anderson S; Nicol M; Schölvinck E; et alRelman D; Waddell S; Langford P; Sheehan B; Semple L; Wilkinson KA; Wilkinson RJ; Ress S; Hibberd M; Levin M. (Sep 2005). Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-gamma. J Clin Invest. 115:2480-2488. DOI.
  • Maitland K,; Simon Nadel; Andrew J Pollard; Thomas N Williams; Charles R J C Newton; Michael Levin. (6 Aug 2005). Management of severe malaria in children: proposed guidelines for the United Kingdom. BMJ. 331:337-343.
  • Pathan N; Williams EJ; Oragui EE; Stephens AC; Levin M. (Aug 2005). Changes in the interleukin-6/soluble interleukin-6 receptor axis in meningococcal septic shock. Crit Care Med. 33:1839-1844.
  • Ninis N; Phillips C; Bailey L; Pollock JI; Nadel S; Britto J; Maconochie I; Winrow A; et alCoen PG; Booy R; Levin M. (25 Jun 2005). The role of healthcare delivery in the outcome of meningococcal disease in children: case-control study of fatal and non-fatal cases. BRITISH MEDICAL JOURNAL. 330:1475-1478. Author weblink DOI.
  • Griffiths MJ; Shafi MJ; Popper SJ; Hemingway CA; Kortok MM; Wathen A; Rockett KA; Mott R; et alLevin M; Newton CR; Marsh K; Relman DA; Kwiatkowski DP. (15 May 2005). Genomewide analysis of the host response to malaria in Kenyan children. JOURNAL OF INFECTIOUS DISEASES. 191:1599-1611. Author weblink DOI.
  • Wilkinson KA; Simsova M; Schölvinck E; Sebo P; Leclerc C; Vordermeier HM; Dickson SJ; Brown JR; et alDavidson RN; Pasvol G; Levin M; Wilkinson RJ. (May 2005). Efficient Ex vivo stimulation of Mycobacterium tuberculosis-specific T cells by genetically detoxified Bordetella pertussis adenylate cyclase antigen toxoids. Infect Immun. 73:2991-2998. DOI.
  • Maitland K; Pamba A; English M; Peshu N; Marsh K; Newton C; Levin M. (15 Feb 2005). Randomized trial of volume expansion with albumin or saline in children with severe malaria: Preliminary evidence of albumin benefit. CLINICAL INFECTIOUS DISEASES. 40:538-545. Author weblink DOI.
  • Kampmann B; Hemingway C; Stephens A; Davidson R; Goodsall A; Anderson S; Nicol M; Scholvinck E; et alRelman D; Waddell S; Langford P; Sheehan B; Semple L; Wilkinson KA; Wilkinson RJ; Ress S; Hibberd M; Levin M. (2005). Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-gamma. J Clin Invest. 115:2480-2488.
  • Maitland K; Pamba A; English ME; Peshu N; Levin M; Marsh K; Newton CRJ. (2005). Pre-transfusion management of children with severe malarial anaemia: a randomised controlled trial of intravascular volume expansion. Br J Haematol. 128:393-400. Publisher weblink.
  • Dorman SE; Picard C; Lammas D; Heyne K; van Dissel JT; Baretto R; Rosenzweig SD; Newport M; et alLevin M; Roesler J; Kumararatne D; Casanova JL; Holland SM. (11 Dec 2004). Clinical features of dominant and recessive interferon gamma receptor 1 deficiencies. LANCET. 364:2113-2121. Author weblink DOI.
  • Roesler J; Horwitz ME; Picard C; Bordigoni P; Davies G; Koscielniak F; Levin M; Veys P; et alReuter UF; Schulz A; Thede C; Klingebiel T; Fischer A; Holland SM; Casanova JL; Friedrich W. (1 Dec 2004). Hematopoietic stem cell transplantation for complete IFN-gamma receptor 1 deficiency: A multi-institutional survey. JOURNAL OF PEDIATRICS. 145:806-812. Author weblink DOI.
  • Kampmann B; Tena GN; Mzazi S; Eley B; Young DB; Levin M. (Nov 2004). Novel human in vitro system for evaluating antimycobacterial vaccines. Infect Immun. 72:6401-6407. DOI.
  • Litt DJ; Savino S; Beddek A; Comanducci M; Sandiford C; Stevens J; Levin M; Ison C; et alPizza M; Rappuoli R; Kroll JS. (15 Oct 2004). Putative vaccine antigens from Neisseria meningitidis recognized by serum antibodies of young children convalescing after meningococcal disease. J Infect Dis. 190:1488-1497. DOI.
  • Zenz W; Zoehrer B; Levin M; Fanconi S; Hatzis TD; Knight G; Mullner M; Faust SN. (1 Aug 2004). Use of recombinant tissue plasminogen activator in children with meningococcal purpura fulminans: A retrospective study. CRITICAL CARE MEDICINE. 32:1777-1780. Author weblink DOI.
  • Fielder AR; Levin M; Tudor-Williams G. (5 Jun 2004). Campaign to revitalise academic medicine - Crisis in UK academia affects academic medicine too. BRITISH MEDICAL JOURNAL. 328:1376-1376. Author weblink DOI.
  • Lichtarowicz-Krynska EJ; Cole TJ; Camacho-Hubner C; Britto J; Levin M; Klein N; Aynsley-Green A. (1 Mar 2004). Circulating aldosterone levels are unexpectedly low in children with acute meningococcal disease. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 89:1410-1414. Author weblink DOI.
  • Schölvinck E; Wilkinson KA; Whelan AO; Martineau AR; Levin M; Wilkinson RJ. (Feb 2004). Gamma interferon-based immunodiagnosis of tuberculosis: comparison between whole-blood and enzyme-linked immunospot methods. J Clin Microbiol. 42:829-831.
  • Pathan N; Hemingway CA; Alizadeh AA; Stephens AC; Boldrick JC; Oragui EE; McCabe C; Welch SB; et alWhitney A; O'Gara P; Nadel S; Relman DA; Harding SE; Levin M. (17 Jan 2004). Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock. Lancet. 363:203-209. DOI.
  • Barton P; Kalil AC; Nadel S; Goldstein B; Okhuysen-Cawley R; Brilli RJ; Takano JS; Martin LD; et alQuint P; Yeh TS; Dalton HJ; Gessouron MR; Brown KE; Betts H; Levin M; Macias WL; Small DS; Wyss VL; Bates BM; Utterback BG; Giroir BP. (1 Jan 2004). Safety, pharmacokinetics, and pharmacodynamics of drotrecogin alfa (activated) in children with severe sepsis. PEDIATRICS. 113:7-17. Author weblink DOI.
  • Haralambous E; Hibberd ML; Hermans PW; Ninis N; Nadel S; Levin M. (Dec 2003). Role of functional plasminogen-activator-inhibitor-1 4G/5G promoter polymorphism in susceptibility, severity, and outcome of meningococcal disease in Caucasian children. Crit Care Med. 31:2788-2793. DOI.
  • Ison CA; Anwar N; Cole MJ; Pollard AJ; Morley SL; Fidler K; Sandiford C; Banks J; et alKroll SJ; Levin M. (Oct 2003). Age dependence of in vitro survival of meningococci in whole blood during childhood. Pediatr Infect Dis J. 22:868-873. DOI.
  • Pathan N; Faust SN; Levin M. (Jul 2003). Pathophysiology of meningococcal meningitis and septicaemia. Arch Dis Child. 88:601-607.
  • Maitland K; Levin M; English M; Mithwani S; Peshu N; Marsh K; Newton CRJC. (1 Jun 2003). Severe P-falciparum malaria in Kenyan children: evidence for hypovolaemia. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE. 96:427-434. Author weblink DOI.
  • Haralambous E; Weiss HA; Radalowicz A; Hibberd ML; Booy R; Levin M. (Jun 2003). Sibling familial risk ratio of meningococcal disease in UK Caucasians. Epidemiol Infect. 130:413-418.
  • Tena GN; Young DB; Eley B; Henderson H; Nicol MP; Levin M; Kampmann B. (15 May 2003). Failure to control growth of mycobacteria in blood from children infected with human immunodeficiency virus and its relationship to T cell function. JOURNAL OF INFECTIOUS DISEASES. 187:1544-1551. Author weblink DOI.
  • Smirnova I; Mann N; Dols A; Derkx HH; Hibberd ML; Levin M; Beutler B. (13 May 2003). Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 100:6075-6080. Author weblink DOI.
  • Burgner D; Levin M. (1 Jan 2003). Genetic susceptibility to infectious diseases. PEDIATRIC INFECTIOUS DISEASE JOURNAL. 22:1-6. Author weblink DOI.
  • Pathan N; Sandiford C; Harding SE; Levin M. (Oct 2002). Characterization of a myocardial depressant factor in meningococcal septicemia. Crit Care Med. 30:2191-2198. DOI.
  • Harrison OB; Robertson BD; Faust SN; Jepson MA; Goldin RD; Levin M; Heyderman RS. (Sep 2002). Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo. Infect Immun. 70:5193-5201.
  • Wills BA; Oragui EE; Stephens AC; Daramola OA; Dung NM; Loan HT; Chau NV; Chambers M; et alStepniewska K; Farrar JJ; Levin M. (1 Aug 2002). Coagulation abnormalities in dengue hemorrhagic Fever: serial investigations in 167 Vietnamese children with Dengue shock syndrome. Clin Infect Dis. 35:277-285. DOI.
  • Jacobs M; Levin M. (Jul 2002). An improved endothelial barrier model to investigate dengue haemorrhagic fever. J Virol Methods. 104:173-185.
  • Brogan PA; Bose A; Burgner D; Shingadia D; Tulloh R; Michie C; Klein N; Booy R; et alLevin M; Dillon MJ. (Apr 2002). Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research. Arch Dis Child. 86:286-290.
  • Faust SN; Heyderman RS; Levin M. (13 Dec 2001). Endothelial protein C activation in meningococcal sepsis. Reply. NEW ENGLAND JOURNAL OF MEDICINE. 345:1777-1777. Author weblink.
  • Morley SL; Cole MJ; Ison CA; Camaraza MA; Sotolongo F; Anwar N; Cuevas I; Carbonero M; et alCampa HC; Sierra G; Levin M. (Nov 2001). Immunogenicity of a serogroup B meningococcal vaccine against multiple Neisseria meningitidis strains in infants. Pediatr Infect Dis J. 20:1054-1061.
  • Booy R; Habibi P; Nadel S; de Munter C; Britto J; Morrison A; Levin M; Meningococcal Research Group. (Nov 2001). Reduction in case fatality rate from meningococcal disease associated with improved healthcare delivery. Arch Dis Child. 85:386-390.
  • Faust SN; Levin M; Harrison OB; Goldin RD; Lockhart MS; Kondaveeti S; Laszik Z; Esmon CT; et alHeyderman RS. (9 Aug 2001). Dysfunction of endothelial protein C activation in severe meningococcal sepsis. N Engl J Med. 345:408-416. DOI.
  • Sandell JM; Ramnarayan P; Welch S; Levin M; Britto J. (7 Jul 2001). Meningococcal disease due to strain W135. Lancet. 358:76.
  • Faust SN; Heyderman RS; Levin M. (Jul 2001). Coagulation in severe sepsis: a central role for thrombomodulin and activated protein C. Crit Care Med. 29:S62-S67.
  • Eling M; Stephens AC; Oragui EE; Rivers RP; Levin M. (Feb 2001). Tissue factor pathway inhibitor (TFPI) levels in the plasma and urine of children with meningococcal disease. Thromb Haemost. 85:240-244.
  • Pathan N; Faust SN; Levin M. (2001). Bacterial meningitis and brain abscess. Medicine. 29:49-54.
  • Bolt P; Britto J; Nadel S; Levin M. (1 Jan 2001). Meningococcal disease due to W135: fresh public health concerns. ARCHIVES OF DISEASE IN CHILDHOOD. 84:90-91. Author weblink.
  • Hibberd M; Summerfield JA; Levin M. (2001). Variation in the mannose binding lectin (MBL) gene and susceptibility to sepsis. Sepsis. 201-207.
  • Pollard AJ; Levin M. (16 Dec 2000). Production of low-avidity antibody by infants after infection with serogroup B meningococci. LANCET. 356:2065-2066. Author weblink DOI.
  • Levin M; Newport M. (Nov 2000). Inherited predisposition to mycobacterial infection: historical considerations. Microbes Infect. 2:1549-1552.
  • Levin M; Quint PA; Goldstein B; Barton P; Bradley JS; Shemie SD; Yeh T; Kim SS; et alCafaro DP; Scannon PJ; Giroir BP. (16 Sep 2000). Recombinant bactericidal/permeability-increasing protein (rBPI(21)) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. LANCET. 356:961-967. Author weblink DOI.
  • Levin M; Quint PA; Goldstein B; Barton P; Bradley JS; Shemie SD; Yeh T; Kim SS; et alCafaro DP; Scannon PJ; Giroir BP. (16 Sep 2000). Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group. Lancet. 356:961-967.
  • Kampmann B; Gaora PO; Snewin VA; Gares MP; Young DB; Levin M. (Sep 2000). Evaluation of human antimycobacterial immunity using recombinant reporter mycobacteria. J Infect Dis. 182:895-901. DOI.
  • Pathan N; Nadel S; Levin M. (Sep 2000). Pathophysiology and management of meningococcal septicaemia. J R Coll Physicians Lond. 34:436-444.
  • Mehta N; Levin M. (15 Aug 2000). Management and prevention of meningococcal disease. Hosp Pract (Minneap). 35:75-86.
  • Thiru Y; Pathan N; Bignall S; Habibi P; Levin M. (1 Aug 2000). A myocardial cytotoxic process is involved in the cardiac dysfunction of meningococcal septic shock. CRITICAL CARE MEDICINE. 28:2979-2983. Author weblink DOI.
  • Oragui EE; Nadel S; Kyd P; Levin M. (Aug 2000). Increased excretion of urinary glycosaminoglycans in meningococcal septicemia and their relationship to proteinuria. Crit Care Med. 28:3002-3008.
  • Faust SN; Heyderman RS; Levin M. (Jun 2000). Disseminated intravascular coagulation and purpura fulminans secondary to infection. Baillieres Best Pract Res Clin Haematol. 13:179-197. DOI.
  • Curtis N; Goodsall A; Levin M. (1 Apr 2000). Evidence that staphylococcal toxic shock syndrome and Kawasaki Disease share a common etiology. PEDIATRIC RESEARCH. 47:562-562. Author weblink.
  • Davies MS; Nadel S; Habibi P; Levin M; Hunt DM. (Apr 2000). The orthopaedic management of peripheral ischaemia in meningococcal septicaemia in children. J Bone Joint Surg Br. 82:383-386.
  • Pollard AJ; Levin M. (1 Apr 2000). Vaccines for prevention of meningococcal disease. PEDIATRIC INFECTIOUS DISEASE JOURNAL. 19:333-345. Author weblink DOI.
  • Rangel L; Garralda ME; Levin M; Roberts H. (Mar 2000). The course of severe chronic fatigue syndrome in childhood. J R Soc Med. 93:129-134.
  • Garralda E; Rangel L; Levin M; Roberts H; Ukoumunne O. (Dec 1999). Psychiatric adjustment in adolescents with a history of chronic fatigue syndrome. J Am Acad Child Adolesc Psychiatry. 38:1515-1521. DOI.
  • Ison CA; Anwar N; Cole MJ; Galassini R; Heyderman RS; Klein NJ; West J; Pollard AJ; et alMorley S; Levin and the Meningococcal R. (Oct 1999). Assessment of immune response to meningococcal disease: comparison of a whole-blood assay and the serum bactericidal assay. Microb Pathog. 27:207-214. DOI.
  • Kondaveeti S; Hibberd ML; Booy R; Nadel S; Levin M. (Oct 1999). Effect of the Factor V Leiden mutation on the severity of meningococcal disease. Pediatr Infect Dis J. 18:893-896.
  • Newport M; Levin M. (1 Sep 1999). Genetic susceptibility to tuberculosis. JOURNAL OF INFECTION. 39:117-121. Author weblink DOI.
  • Hermans PWM; Hibberd ML; Booy R; Daramola O; Hazelzet JA; de Groot R; Levin M. (14 Aug 1999). 4G/5G promoter polymorphism in the plasminogen-activator-inhibitor-1 gene and outcome of meningococcal disease. LANCET. 354:556-560. Author weblink DOI.
  • Hibberd ML; Sumiya M; Summerfield JA; Booy R; Levin M. (24 Jul 1999). Mannose-binding lectin and meningococcal disease. LANCET. 354:337-337. Author weblink DOI.
  • Kondaveeti S; Hibberd ML; Levin M. (1 Jul 1999). The insertion/deletion polymorphism in the t-PA gene does not significantly affect outcome of meningococcal disease. THROMBOSIS AND HAEMOSTASIS. 82:161-162. Author weblink.
  • Levin M; Newport M. (Jul 1999). Understanding the genetic basis of susceptibility to mycobacterial infection. Proc Assoc Am Physicians. 111:308-312.
  • Pollard AJ; Galassini R; Rouppe van der Voort EM; Hibberd M; Booy R; Langford P; Nadel S; Ison C; et alKroll JS; Poolman J; Levin M. (May 1999). Cellular immune responses to Neisseria meningitidis in children. Infect Immun. 67:2452-2463.
  • Pollard AJ; Galassini R; van der Voort EM; Booy R; Langford P; Nadel S; Ison C; Kroll JS; et alPoolman J; Levin M. (May 1999). Humoral immune responses to Neisseria meningitidis in children. Infect Immun. 67:2441-2451.
  • Heyderman RS; Ison CA; Peakman M; Levin M; Klein NJ. (1 May 1999). Neutrophil response to Neisseria meningitidis: Inhibition of adhesion molecule expression and phagocytosis by recombinant bactericidal permeability-increasing protein (rBPI(21)). JOURNAL OF INFECTIOUS DISEASES. 179:1288-1292. Author weblink DOI.
  • Hibberd ML; Sumiya M; Summerfield JA; Booy R; Levin M. (27 Mar 1999). Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease. Meningococcal Research Group. Lancet. 353:1049-1053.
  • Hibberd ML; Sumiya M; Summerfield JA; Booy R; Levin M. (27 Mar 1999). Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease. LANCET. 353:1049-1053. Author weblink DOI.
  • Pollard AJ; Britto J; Nadel S; DeMunter C; Habibi P; Levin M. (Mar 1999). Emergency management of meningococcal disease. Arch Dis Child. 80:290-296.
  • Nadel S; Britto J; Booy R; Maconochie I; Habibi P; Levin M. (Sep 1998). Avoidable deficiencies in the delivery of health care to children with meningococcal disease. J Accid Emerg Med. 15:298-303.
  • Festa M; Nadel S; Levin M; Gamble J. (1 Aug 1998). Microvascular changes in meningococcal disease. JOURNAL OF VASCULAR RESEARCH. 35:91-91. Author weblink.
  • Pollard AJ; Faust SN; Levin M. (1 Jul 1998). Meningitis and meningococcal septicaemia - Extended review. JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF LONDON. 32:319-328. Author weblink.
  • Pollard AJ; Faust SN; Levin M. (Jul 1998). Meningitis and meningococcal septicaemia. J R Coll Physicians Lond. 32:319-328.
  • Levin M. (Jun 1998). Experimental treatments of meningococcal sepsis. Curr Opin Infect Dis. 11:309-311.
  • Curtis N; Levin M. (Feb 1998). Kawasaki disease thirty years on. Curr Opin Pediatr. 10:24-33.
  • Nadel S; De Munter C; Britto J; Levin M; Habibi P. (1998). Albumin: saint or sinner?. Archives of Disease in Childhood. 79.
  • Jouanguy E; Lamhamedi-Cherradi S; Altare F; Fondaneche MC; Tuerlinckx D; Blanche S; Emile JF; Gaillard JL; et alSchreiber R; Levin M; Fischer A; Hivroz C; Casanova JL. (1 Dec 1997). Partial interferon-gamma receptor 1 deficiency in a child with tuberculoid bacillus Calmette-Guerin infection and a sibling with clinical tuberculosis. JOURNAL OF CLINICAL INVESTIGATION. 100:2658-2664. Author weblink DOI.
  • Altare F; Jouanguy E; Newport M; Lamhamedi S; Fischer A; Levin M; Casanova JL. (1 Jul 1997). IFNgR1, a human mycobacterial susceptibility candidate gene. BULLETIN DE L INSTITUT PASTEUR. 95:143-146. Author weblink DOI.
  • Heyderman RS; Ison CA; Peters M; Peakman M; Levin M; Klein NJ. (1 Jun 1997). Characterisation of platelet activation in an ex-vivo whole blood model of meningococcal bacteraemia. THROMBOSIS AND HAEMOSTASIS. P2512-P2512. Author weblink.
  • Levin M. (1 Jun 1997). Paediatric and neonatal infections. CURRENT OPINION IN INFECTIOUS DISEASES. 10:209-212. Author weblink DOI.
  • Heyderman RS; Klein NJ; Daramola OA; Hammerschmidt S; Frosch M; Robertson BD; Levin M; Ison CA. (May 1997). Induction of human endothelial tissue factor expression by Neisseria meningitidis: the influence of bacterial killing and adherence to the endothelium. Microb Pathog. 22:265-274. DOI.
  • Summerfield JA; Sumiya M; Levin M; Turner MW. (26 Apr 1997). Association of mutations in mannose binding protein gene with childhood infection in consecutive hospital series. BMJ. 314:1229-1232.
  • Booy R; Nadel S; Hibberd M; Levin M; Newport MJ. (19 Apr 1997). Genetic influence on cytokine production in meningococcal disease. LANCET. 349:1176-1176. Author weblink DOI.
  • Levin M; Newport M. (Jan 1997). Unravelling the genetic basis of susceptibility to mycobacterial infection. J Pathol. 181:5-7. DOI.
  • Newport MJ; Huxley CM; Huston S; Hawrylowicz CM; Oostra BA; Williamson R; Levin M. (26 Dec 1996). A mutation in the interferon-gamma-receptor gene and susceptibility to mycobacterial infection. N Engl J Med. 335:1941-1949. DOI.
  • Jouanguy E; Altare F; Lamhamedi S; Revy P; Emile JF; Newport M; Levin M; Blanche S; et alSeboun E; Fischer A; Casanova JL. (26 Dec 1996). Interferon-gamma-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection. NEW ENGLAND JOURNAL OF MEDICINE. 335:1956-1961. Author weblink DOI.
  • Nadel S; Newport MJ; Booy R; Levin M. (Oct 1996). Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease. J Infect Dis. 174:878-880.
  • Pollard AJ; Isaacs A; Hermione Lyall EG; Curtis N; Lee K; Walters S; Levin M. (3 Aug 1996). Potentially lethal bacterial infection associated with varicella zoster virus. BMJ. 313:283-285.
  • Britto J; Habibi P; Walters S; Levin M; Nadel S. (Mar 1996). Systemic complications associated with bacterial tracheitis. Arch Dis Child. 74:249-250.
  • Chan B; Kalabalikis P; Klein N; Heyderman R; Levin M. (1996). Assessment of the effect of candidate anti-inflammatory treatments on the interaction between meningococci and inflammatory cells in vitro in a whole blood model. Biotherapy. 9:221-228.
  • D'Souza S; Levin M; Faith A; Yssel H; Bennett B; Lake RA; Brown IN; Lamb JR. (Jan 1996). Defective antigen processing associated with familial disseminated mycobacteriosis. Clin Exp Immunol. 103:35-39.
  • Newport M; Levin M; Blackwell J; Shaw MA; Williamson R; Huxley C. (Nov 1995). Evidence for exclusion of a mutation in NRAMP as the cause of familial disseminated atypical mycobacterial infection in a Maltese kindred. J Med Genet. 32:904-906.
  • Britto J; Nadel S; Maconochie I; Levin M; Habibi P. (30 Sep 1995). Morbidity and severity of illness during interhospital transfer: impact of a specialised paediatric retrieval team. BMJ. 311:836-839.
  • Evans JA; Marriage SC; Walters MD; Levin M. (13 May 1995). Unsuspected HIV infection presenting in first year of life. BMJ. 310:1235-1236.
  • Britto J; Nadel S; Habibi P; Levin M. (May 1995). Gastrointestinal perforation complicating meningococcal disease. Pediatr Infect Dis J. 14:393-394.
  • Curtis N; Zheng R; Lamb JR; Levin M. (Apr 1995). Evidence for a superantigen mediated process in Kawasaki disease. Arch Dis Child. 72:308-311.
  • Ison CA; Heyderman RS; Klein NJ; Peakman M; Levin M. (Feb 1995). Whole blood model of meningococcal bacteraemia--a method for exploring host-bacterial interactions. Microb Pathog. 18:97-107.
  • Levin M; Newport MJ; D'Souza S; Kalabalikis P; Brown IN; Lenicker HM; Agius PV; Davies EG; et alThrasher A; Klein N. (14 Jan 1995). Familial disseminated atypical mycobacterial infection in childhood: a human mycobacterial susceptibility gene?. Lancet. 345:79-83.
  • Newport M; Levin M. (Dec 1994). Familial disseminated atypical mycobacterial disease. Immunol Lett. 43:133-138.
  • Stephens AC; Zheng RQ; Russell AR; Levin M; Rivers RP. (1 Oct 1994). Production of tissue factor by monocyte progenitor cells. Thromb Res. 76:33-45.
  • Klein NJ; Heyderman RS; Levin M. (16 Jun 1993). Management of meningococcal infections. Br J Hosp Med. 50:42-49.
  • Klein NJ; Levin M; Strobel S; Finn A. (Apr 1993). Degradation of glycosaminoglycans and fibronectin on endotoxin-stimulated endothelium by adherent neutrophils: relationship to CD11b/CD18 and L-selectin expression. J Infect Dis. 167:890-898.
  • Nadel S; Levin M. (Feb 1993). Kawasaki disease. Curr Opin Pediatr. 5:29-34.
  • Heyderman RS; Klein NJ; Shennan GI; Levin M. (15 Sep 1992). Reduction of the anticoagulant activity of glycosaminoglycans on the surface of the vascular endothelium by endotoxin and neutrophils: evaluation by an amidolytic assay. Thromb Res. 67:677-685.
  • Klein NJ; Shennan GI; Heyderman RS; Levin M. (Aug 1992). Alteration in glycosaminoglycan metabolism and surface charge on human umbilical vein endothelial cells induced by cytokines, endotoxin and neutrophils. J Cell Sci. 102 ( Pt 4):821-832.
  • Klein NJ; Heyderman RS; Levin M. (Feb 1992). Antibiotic choices for meningitis beyond the neonatal period. Arch Dis Child. 67:157-159.
  • Torres-Martínez C; Mehta D; Butt A; Levin M. (Jan 1992). Streptococcus associated toxic shock. Arch Dis Child. 67:126-130.
  • Levin M; Tizard EJ; Dillon MJ. (Dec 1991). Kawasaki disease: recent advances. Arch Dis Child. 66:1369-1372.

Chapters in books

  • Cooke GS; Levin M; Wilkinson RJ; Pasvol G. Host Genetics and Susceptibility to Infection. In Tropcial Infectious Diseases: Principles, Pathogens and Practice. Third. Guerrant RL (ed); Walker DH (ed); Weller PF (ed). Elsevier (2011).

Conferences

  • Wills B; Diet TV; Trung DT; Goldin R; Lad A; Dung NM; Levin M; Farrar J. Immunohistochemistry on skin biopsies from Vietnamese patients with dengue shock syndrome. 56th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene, 4 Nov 2007 - 8 Nov 2007. 77:130-130. AMER SOC TROP MED & HYGIENE (1 Nov 2007). Author weblink.
  • Burns JC; Shimizu C; Nievergelt CM; Shike H; Sundel RP; Newburger JW; Baker AL; Burgner D; et alHibberd ML; Levin M; Schork NJ. Angiotensin converting enzyme and beta 3-integrin influence susceptibility to Kawasaki disease. 79th Annual Scientific Session of the American-Heart-Association, 12 Nov 2006 - 15 Nov 2006. 114:584-584. LIPPINCOTT WILLIAMS & WILKINS (31 Oct 2006). Author weblink.
  • Wills BA; Oragui EE; Dung NM; Loan HT; Chau NV; Farrar JJ; Levin M. Size and charge characteristics of the protein leak in dengue shock syndrome. 52nd Meeting of the American-Society-for-Tropical-Medicine-and-Hygiene, Dec 2003. 190:810-818. UNIV CHICAGO PRESS (15 Aug 2004). Author weblink DOI.
  • Pathan N; Stephens A; Oragui E; Levin M; McAbe C; O'Gara P; Harding S. IL6 and TNF alpha: A double-edged sword in the myocardial dysfunction of meningococcal septicaemia. 32nd Critical Care Congress of the Society-of-Critical-Care-Medicine. 31:A49-A49. (Feb 2003).
  • Pathan N; Hemingway C; Levin M; Whitney A; Popper S; Relman D. The complexity of the inflammatory response to meningococcal sepsis revealed by gene expression profiling using cDNA microarrays. 32nd Critical Care Congress of the Society-of-Critical-Care-Medicine, 28 Jan 2003 - 2 Feb 2003. 31:A47-A47. LIPPINCOTT WILLIAMS & WILKINS (1 Feb 2003). Author weblink.
  • Burgner D; Curtis N; Goodsall A; Xixi E; Levin M. Novel staphylococcal superantigens in children with Kawasaki disease. 7th International Kawasaki Disease Symposium, 4 Dec 2001 - 7 Dec 2001. 53:159-159. INT PEDIATRIC RESEARCH FOUNDATION, INC (1 Jan 2003). Author weblink.
  • Pathan N; Stephens A; Oragui E; Levin M. IL6 and TNF alpha: A double-edged sword in the myocardial dysfunction of meningococcal septicaemia?. 32nd Critical Care Congress. 30:A49-A49. (Dec 2002).
  • Pathan N; Hemingway C; Levin M. The complexity of the inflammatory response to meningococcal sepsis revealed by gene expression profiling using CDNA microarrays. 32nd Critical Care Congress. 30:A47-A47. (Dec 2002).
  • Giroir BP; Scannon PJ; Levin M. Bactericidal/permeability-increasing protein - Lessons learned from the phase III, randomized, clinical trial of rBPI(21) for adjunctive treatment of children with severe meningococcemia. Margaux Conference on Critical Illness, 8 Nov 2000 - 12 Nov 2000. 29:S130-S135. LIPPINCOTT WILLIAMS & WILKINS (1 Jul 2001). Author weblink DOI.
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