Professor Mary A Ritter MA, DPhil, FRCPath, FCGI, FRSA

Publications


Journals

  • Ritter MA. (2000). Polyclonal and monoclonal antibodies. Methods Mol Med. 40:23-34. DOI.
  • Shrimpton RE; Butler M; Morel AS; Eren E; Hue SS; Ritter MA. (Mar 2009). CD205 (DEC-205): a recognition receptor for apoptotic and necrotic self. Mol Immunol. 46:1229-1239. DOI.
  • Butler M; Morel AS; Jordan WJ; Eren E; Hue S; Shrimpton RE; Ritter MA. (Mar 2007). Altered expression and endocytic function of CD205 in human dendritic cells, and detection of a CD205-DCL-1 fusion protein upon dendritic cell maturation. Immunology. 120:362-371. DOI.
  • RITTER MA; MORRIS RJ. (1980). THY-1 ANTIGEN - SELECTIVE ASSOCIATION IN LYMPHOID ORGANS WITH THE VASCULAR BASEMENT-MEMBRANE INVOLVED IN LYMPHOCYTE RECIRCULATION. IMMUNOLOGY. 39:85-91.
  • RITTER MA; MORRIS RJ; GOLDSCHNEIDER I. (1980). HIDDEN THY-1 ANTIGEN IN A SUB-POPULATION OF MOUSE BONE-MARROW CELLS. IMMUNOLOGY. 39:375-384.
  • WALSH FS; RITTER MA. (1981). SURFACE-ANTIGEN DIFFERENTIATION DURING HUMAN MYOGENESIS IN CULTURE. NATURE. 289:60-64.
  • DHUT S; RITTER MA; WALSH FS. (1981). SPECIFIC CELL-SURFACE ANTIGENS OF HUMAN-MUSCLE CELLS IN CULTURE. J PHYSIOL-LONDON. 312:P34-P34.
  • RITTER MA; SAUVAGE CA; COTMORE SF. (1981). THE HUMAN THYMUS MICRO-ENVIRONMENT - INVIVO IDENTIFICATION OF THYMIC NURSE CELLS AND OTHER ANTIGENICALLY-DISTINCT SUB-POPULATIONS OF EPITHELIAL-CELLS. IMMUNOLOGY. 44:439-446.
  • KEMSHEAD JT; RITTER MA; COTMORE SF; GREAVES MF. (1982). HUMAN THY-1 - EXPRESSION ON THE CELL-SURFACE OF NEURONAL AND GLIAL-CELLS. BRAIN RES. 236:451-461.
  • RUDLAND PS; WARBURTON MJ; MONAGHAN P; RITTER MA. (1982). THY-1 ANTIGEN ON NORMAL AND NEOPLASTIC RAT MAMMARY TISSUES - CHANGES IN LOCATION AND AMOUNT OF ANTIGEN DURING DIFFERENTIATION OF CULTURED STEM-CELLS. J NATL CANCER I. 68:799-811.
  • GREAVES MF; HARIRI G; NEWMAN RA; SUTHERLAND DR; RITTER MA; RITZ J. (1983). SELECTIVE EXPRESSION OF THE COMMON ACUTE LYMPHOBLASTIC-LEUKEMIA (GP100) ANTIGEN ON IMMATURE LYMPHOID-CELLS AND THEIR MALIGNANT COUNTERPARTS. BLOOD. 61:628-639.
  • RITTER MA; SAUVAGE CA; DELIA D. (1983). HUMAN THY-1 ANTIGEN - CELL-SURFACE EXPRESSION ON EARLY LYMPHOCYTE-T AND LYMPHOCYTE-B. IMMUNOLOGY. 49:555-564.
  • RITTER MA; SAUVAGE CA; PEGRAM SM; MYERS CD; DALCHAU R; FABRE JW. (1985). THE HUMAN LEUCOCYTE-COMMON (LC) MOLECULE - DISSECTION OF LEUKEMIAS USING MONOCLONAL-ANTIBODIES DIRECTED AGAINST FRAMEWORK AND RESTRICTED ANTIGENIC DETERMINANTS. LEUKEMIA RES. 9:1249-1254.
  • KATZ FE; LAM G; RITTER MA. (1985). THE HUMAN LEUCOCYTE-COMMON ANTIGEN - DIFFERENTIAL EXPRESSION OF FRAMEWORK AND RESTRICTED ANTIGENIC DETERMINANTS ON EARLY HEMATOPOIETIC PROGENITORS. BRIT J HAEMATOL. 61:695-705.
  • COURTENAYLUCK NS; EPENETOS AA; SIVOLAPENKO GB; LARCHE M; BARKANS JR; RITTER MA. (15 Oct 1988). DEVELOPMENT OF ANTI-IDIOTYPIC ANTIBODIES AGAINST TUMOR-ANTIGENS AND AUTO-ANTIGENS IN OVARIAN-CANCER PATIENTS TREATED INTRAPERITONEALLY WITH MOUSE MONOCLONAL-ANTIBODIES. LANCET. 2:894-897.
  • ALJABAARI B; LADYMAN HM; LARCHE M; SIVOLAPENKO GB; EPENETOS AA; RITTER MA. (Jun 1989). ELEVATED EXPRESSION OF THE INTERLEUKIN-4 RECEPTOR IN CARCINOMA - A TARGET FOR IMMUNOTHERAPY. BRIT J CANCER. 59:910-914.
  • SIVOLAPENKO GB; KANARIOU M; EDWARDS RJ; EPENETOS AA; RITTER MA. (Oct 1989). IMMUNOSUPPRESSION BY IMMUNOGLOBULIN DEAGGREGATION IS NOT EFFECTIVE IN REDUCING THE ANTI-XENOGENEIC IMMUNOGLOBULIN RESPONSE - EXPERIMENTAL AND CLINICAL-STUDIES. BRIT J CANCER. 60:511-516.
  • TUNGEKAR MF; TURLEY H; DUNNILL MS; GATTER KC; RITTER MA; HARRIS AL. (Feb 1991). INTERLEUKIN-4 RECEPTOR EXPRESSION ON HUMAN LUNG-TUMORS AND NORMAL LUNG. J PATHOL. 163:A164-A164.
  • SIVOLAPENKO GB; MORENO C; SMITH W; CORVALAN J; RITTER MA; EPENETOS AA. (Aug 1991). XENOGENEIC MONOCLONAL-ANTIBODIES IN THE MANAGEMENT OF CANCER - CONTROL OF THEIR INVIVO IMMUNOGENICITY AND INDUCTION OF SPECIFIC UNRESPONSIVENESS USING AN ANTIBODY-DRUG IMMUNOCONJUGATE. BRIT J CANCER. 64:281-287.
  • Almarri A; El Dwick N; Al Kabi S; Sleem K; Rashed A; Ritter MA; Batchelor JR. (Apr 1998). Interferon-alpha therapy in HCV hepatitis: HLA phenotype and cirrhosis are independent predictors of clinical outcome. HUM IMMUNOL. 59:239-242.
  • Scupoli MT; Vinante F; Vincenzi C; Nadali G; Ritter MA; Eeren E; Santini F; Pizzolo G. (16 Nov 2001). Bone marrow-, but not thymus-, derived stromal cells inhibit spontaneous apoptosis and induce proliferation in blasts of T-lineage ALL. BLOOD. 98:81A-81A.
  • Scupoli MT; Vinante F; Krampera M; Vincenzi C; Nadali G; Zampieri F; Ritter MA; Eren E; et alSantini F; Pizzolo G. (Nov 2003). Thymic epithelial cells promote survival of human T-cell acute lymphoblastic leukemia blasts: the role of interleukin-7. HAEMATOLOGICA. 88:1229-1237.
  • Stewart JS; Sivolapenko GB; Hird V; Davies KA; Walport M; Ritter MA; Epenetos AA. (1 Feb 1990). Clearance of 131I-labeled murine monoclonal antibody from patients' blood by intravenous human anti-murine immunoglobulin antibody. Cancer Res. 50:563-567.
  • Palmer DB; Viney JL; Ritter MA; Hayday AC; Owen MJ. (1993). Expression of the alpha beta T-cell receptor is necessary for the generation of the thymic medulla. Dev Immunol. 3:175-179.
  • Imami N; Brookes PA; Lombardi G; Hakooz B; Johns M; Goldman JM; Batchelor JR; Lechler RI; et alRitter MA. (15 Apr 1998). Association between interleukin-4-producing T lymphocyte frequencies and reduced risk of graft-versus-host disease. Transplantation. 65:979-988.
  • Imami N; Ladyman HM; Vincents B; al-Tubuly A; Freysdóttir J; Sedibane ML; Taylor-Fishwick DA; Foxwell BM; et alRitter MA. (1998). K21-antigen: a molecule shared by the microenvironments of the human thymus and germinal centers. Dev Immunol. 6:41-52.
  • Reza JN; Ritter MA. (1998). Positive and negative selection in the thymus and the thymic paradox. Dev Immunol. 5:161-168.
  • McKay PF; Imami N; Johns M; Taylor-Fishwick DA; Sedibane LM; Totty NF; Hsuan JJ; Palmer DB; et alGeorge AJ; Foxwell BM; Ritter MA. (Dec 1998). The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family. Eur J Immunol. 28:4071-4083. DOI.
  • Ritter MA; Palmer DB. (Feb 1999). The human thymic microenvironment: new approaches to functional analysis. Semin Immunol. 11:13-21. DOI.
  • Palmer DB; Crompton T; Marandi MB; George AJ; Ritter MA. (Feb 1999). Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development. Immunology. 96:236-245.
  • Howard JK; Lord GM; Matarese G; Vendetti S; Ghatei MA; Ritter MA; Lechler RI; Bloom SR. (Oct 1999). Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice. J Clin Invest. 104:1051-1059. DOI Open Access copy.
  • Midulla M; Verma R; Pignatelli M; Ritter MA; Courtenay-Luck NS; George AJ. (1 Jan 2000). Source of oncofetal ED-B-containing fibronectin: implications of production by both tumor and endothelial cells. Cancer Res. 60:164-169.
  • Johns M; George AJ; Ritter MA. (26 May 2000). In vivo selection of sFv from phage display libraries. J Immunol Methods. 239:137-151.
  • Tan PH; Yates JB; Xue SA; Chan C; Jordan WJ; Harper JE; Watson MP; Dong R; et alRitter MA; Lechler RI; Lombardi G; George AJ. (1 Nov 2005). Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression. Blood. 106:2936-2943. DOI.
  • Freysdottir J; Ritter MA. (2001). Antibodies to human thymic epithelium form part of the murine autoreactive repertoire. Dev Immunol. 8:75-93.
  • Jordan WJ; Ritter MA. (1 Feb 2002). Optimal analysis of composite cytokine responses during alloreactivity. J Immunol Methods. 260:1-14.
  • De Lorenzo C; Palmer DB; Piccoli R; Ritter MA; D'Alessio G. (Jun 2002). A new human antitumor immunoreagent specific for ErbB2. Clin Cancer Res. 8:1710-1719.
  • Solomou K; Ritter MA; Palmer DB. (Jun 2002). Somatostatin is expressed in the murine thymus and enhances thymocyte development. Eur J Immunol. 32:1550-1559. DOI.
  • Blackburn CC; Manley NR; Palmer DB; Boyd RL; Anderson G; Ritter MA. (Aug 2002). One for all and all for one: thymic epithelial stem cells and regeneration. Trends Immunol. 23:391-395.
  • Jordan WJ; Brookes PA; Szydlo RM; Goldman JM; Lechler RI; Ritter MA. (15 Jan 2004). IL-13 production by donor T cells is prognostic of acute graft-versus-host disease following unrelated donor stem cell transplantation. Blood. 103:717-724. DOI.
  • Tan PH; Beutelspacher SC; Xue SA; Wang YH; Mitchell P; McAlister JC; Larkin DF; McClure MO; et alStauss HJ; Ritter MA; Lombardi G; George AJ. (15 May 2005). Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy. Blood. 105:3824-3832. DOI.
  • Kokkinopoulos I; Jordan WJ; Ritter MA. (May 2005). Toll-like receptor mRNA expression patterns in human dendritic cells and monocytes. Mol Immunol. 42:957-968. DOI.
  • Tan PH; Beutelspacher SC; Wang YH; McClure MO; Ritter MA; Lombardi G; George AJ. (May 2005). Immunolipoplexes: an efficient, nonviral alternative for transfection of human dendritic cells with potential for clinical vaccination. Mol Ther. 11:790-800. DOI.

Conferences

  • Palmer DB; Solomou A; Ritter MA. Functional analysis of the thymic microenvironment using recombinant single chain antibodies. Meeting on New Horizons for Phage Antibody Display Technology. 16:69-69. (2000).
  • Tan PH; Yates J; Xue S; Jordan WJ; Dong R; Ritter MA; Lechler RI; Lombardi G; et alGeorge AJT. Prevention of co-stimulation molecule expression using intracellular CTLA4: a novel strategy for induction of T cell anergy. 7th Congress of the International-Xenotransplantation-Association. 10:531-531. (Sep 2003).
  • Tan PH; Herrera OB; Yates J; Harper JE; Watson MP; Chan C; Xue SA; Jordan WJ; et alDong R; Stauss HJ; Ritter MA; Lechler RI; Lombardi G; George AJT. Creation of tolerogenic antigen presenting cells via intracellular CTLA4: a novel strategy with potential clinical utility in transplantation. Annual Meeting of the Association-of-Surgeons-of-Great-Britian-and-Ireland. 92:72-72. (Apr 2005).
  • Tan PH; Beutelspacher SC; Wang YH; McClure MO; Ritter MA; Lombardi G; George AJT. Immunolipoplexes: An efficient, non-viral alternative for transfection of human dendritic cells with potential for clinical vaccination. 6th American Transplant Congress. 5:367-367. (May 2005).
  • Tan PH; Xue SA; Wang YH; Beutelspacher SC; McAlister JC; Larkin DFP; McClure MO; Stauss HJ; et alRitter MA; Lombardi G; George AJT. Modulation of human dendritic cell function following viral vectors: implications for gene therapy in vaccination. 92:134-134. (Apr 2005).

Patents

  • MR6 antibody. Application: 633819. Published: 1998.
  • Human mini-antibody cytotoxic for tumor cells which express the Erb B2 receptor. Application: PCT/EP02/07671. II UDSDNF. Published: Jul 2002.
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