Publications

Journals

• Millour J; de Olano N; Horimoto Y; Monteiro LJ; Langer JK; Aligue R; Hajji N; Lam EW. (Jun 2011). ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance. Mol Cancer Ther. 10:1046-1058. DOI.
• Burguillos MA; Deierborg T; Kavanagh E; Persson A; Hajji N; Garcia-Quintanilla A; Cano J; Brundin P; et alEnglund E; Venero JL; Joseph B. (21 Apr 2011). Caspase signalling controls microglia activation and neurotoxicity. Nature. 472:319-324. DOI.
• Burguillos MA; Hajji N; Englund E; Persson A; Cenci AM; Machado A; Cano J; Joseph B; et alVenero JL. (Jan 2011). Apoptosis-inducing factor mediates dopaminergic cell death in response to LPS-induced inflammatory stimulus: evidence in Parkinson's disease patients. Neurobiol Dis. 41:177-188. DOI.
• Füllgrabe J; Hajji N; Joseph B. (Aug 2010). Cracking the death code: apoptosis-related histone modifications. Cell Death Differ. 17:1238-1243. DOI.
• Hajji N; Wallenborg K; Vlachos P; Füllgrabe J; Hermanson O; Joseph B. (15 Apr 2010). Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. Oncogene. 29:2192-2204. DOI.
• Hajji N; Wallenborg K; Vlachos P; Nyman U; Hermanson O; Joseph B. (15 May 2008). Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. Oncogene. 27:3134-3144. DOI.
• Gallego M-A; Ballot C; Kluza J; Hajji N; Martoriati A; Castera L; Cuevas C; Formstecher P; et alJoseph B; Kroemer G; Bailly C; Marchetti P. (27 Mar 2008). Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway. ONCOGENE. 27:1981-1992. Author weblink DOI.
• R. Matin, N. Hajji, A. Chikh, C.A. Harwood and D. Bergamaschi. (2008). p63 is implicated in apoptotic deregulation in melanoma. British Journal of Dermatology. Volume 158 Issue 4, Pages 874 - 912.
• Vlachos P; Nyman U; Hajji N; Joseph B. (Aug 2007). The cell cycle inhibitor p57(Kip2) promotes cell death via the mitochondrial apoptotic pathway. Cell Death Differ. 14:1497-1507. DOI.
• Mateos S; Hajji N; Pastor N; Cortés F. (25 Jul 2006). Modulation of radiation response by inhibiting topoisomerase II catalytic activity. Mutat Res. 599:105-115. DOI.
• Hajji N; Mateos S; Pastor N; Domínguez I; Cortés F. (2 May 2005). Induction of genotoxic and cytotoxic damage by aclarubicin, a dual topoisomerase inhibitor. Mutat Res. 583:26-35. DOI.
• Pastor N; Baos R; López-Lázaro M; Jovani R; Tella JL; Hajji N; Hiraldo F; Cortés F. (Jan 2004). A 4 year follow-up analysis of genotoxic damage in birds of the Doñana area (south west Spain) in the wake of the 1998 mining waste spill. Mutagenesis. 19:61-65.
• Hajji N; Pastor N; Mateos S; Domínguez I; Cortés F. (29 Sep 2003). DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193. Mutat Res. 530:35-46.

Chapters in books

• Hajji N; Joseph B. Epigenetic Regulation of Cell Life and Death Decisions and Deregulation in Cancer. In Epigenetics, Disease and Behaviour. Essays Biochem. (2010) 48, (121–146). (2010). Publisher weblink.

Conferences

• Hajji N. Molecular mechanisms and outcomes of arsenic-induced alterations in histone acetylation. Oral presentation. Epigenetics in Environmental Research, MRC-HPA Centre conference, Imperial College, London, UK 2009., 2009.
• Matin RN; Hajji N; Hajji N; Chikh A; Harwood CA; Bergamaschi D. p63 is implicated in apoptotic deregulation in melanoma. BSID 2008: University of OXFORD, UK., 2008.
• Hajji N., Vlachos P., Nyman U., and Joseph B. Chemosensitization of NSCLC cells upon pan-HDAC inhibition proceeds through caspase-mediated AIF-dependent mitochondrial death pathway. 5th Annual KI Cancer Meeting,. (2006).
• Hajji N., Vlachos P., Nyman U., and Joseph B. Chemosensitization of NSCLC cells upon pan-HDAC inhibition proceeds through caspase-mediated AIF-dependent mitochondrial death pathway. 14th Euroconference on Apoptosis. 14th Euroconference on Apoptosis,, 2006.
• Hajji N., Pastor N., Baos, López-Lázaro, M., Jovani, R., Tella, J. L., Hiraldo, F., Cortés, F. A 4 year follow-up analysis of genotoxic damage in birds of Donana area (south west Spain) in the wake of the 1998 waste spill. X Meeting of the Spanish Society for Cell Biology, 2003.
• Vlachos P., Nyman U., Hajji N., and Joseph B. p57KIP2 promotes staurosporine induced-apoptotic mitochondrial changes and cell death. 5th Annual KI Cancer. 5th Annual KI Cancer Meeting,, 2006.
• Mateos S; Hajji N; Pastor N; Cantero G; Domínguez I; Cortés F. Modulation of radiation response by inhibiting topoisomerase II catalytic activity. XV Reunión Científica de la Sociedad Española de Mutagénesis Ambiental, 2006.
• Pastor N., Mateos S., Mateos J., Dominguez I., Hajji N., Cortés F. DNA repair kinetics in X-irradiated CHO cells depends on topoisomerase II activity. International Congress of the international radiation protection association., 2004.
• Vlachos P., Nyman U., Hajji N., and Joseph B.. p57KIP2 promotes staurosporine induced-apoptotic mitochondrial changes and cell death. 14th Euroconference on Apoptosis,, 2006.
• Hajji N., Vlachos P., Nyman U., and Joseph B. Histone deacetylase inhibitors sensitize H157 non small cell lung cancer cells to etoposide-induced cell death: epigenetic control and/or mechanistic action. 4th Annual KI Cancer Meeting,, 2007.
• Pastor N., Hajji N., Domínguez I., Mateos S., Cortés F. Cytotoxic and Genotoxic effects of two catalytic inhibitors of topoisomerase II in CHO cells. 32nd Annual Meeting of European Environmental Mutagen Society (EEMS. 32nd Annual Meeting of European Environmental Mutagen Society (EEMS). DNA damage and Repair Fundamental Aspects and Contribution to Human Disorders., 2002.
• Santiago Mateos, Inmaculada Domínguez, Nuria Pastor, Gloria Cantero, Nabil Hajji and Felipe Cortés. Extensive DNA hypomethylation induces endoreduplication in cultured Chinese hamster cells. 35th Annual Meeting of European Environmental Mutagen Society (EEMS). DNA damage and Repair Fundamental Aspects and Contribution to Human Disorders., 2005.
• Pastor N., Hajji N., Cortés F. Miguel López-Lázaro, José Luis Tella, Raquel Boas, Manuela G .Fernando Hiraldo. The Aznalcóllar mine harmful effects on storks and kites. The Aznalcóllar mine harmful effects on storks and kites., 2003.
• Cortés F., Pastor N., Mateos S., Cantero G., Domínguez I.,Hajji N. Halogen substitution protects DNA from “cleavable complex” stabilization by the topoisomerase II poison amsacrine: On the importance of the enzyme for chromosome segregation. 35th Annual Meeting of European Environmental Mutagen Society (EEMS)DNA damage and Repair Fundamental Aspects and Contribution to Human Disorders, 2005.
• Hajji N., Pastor N., Mateos S., Cortés F. DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193. Meeting: X Meeting of Spanish Society for Cell Biology., 2003.