Dr Nadire N. Ali

Publications


Journals

  • Reed DM; Foldes G; Badiger RV; Ali NN; Wheeler-Jones CP; Paul-Clark MJ; Harding SE; Mitchell JA. (Oct 2011). TLR3 AND INTERFERON FUNCTION IN HUMAN EMBRYONIC STEM CELL-DERIVED ENDOTHELIAL CELLS (HESC-EC): RELEVANCE TO VIRAL IMMUNITY. HEART. 97:12-12. DOI.
  • Chahine MN; Mioulane M; Foldes G; Lyon A; Ali NN; Schneider MD; Harding SE. (Oct 2011). NUCLEAR PROTEIN IMPORT MEDIATES PHENYLEPHRINE-INDUCED HYPERTROPHY IN ADULT AND HUMAN EMBRYONIC STEM CELL-DERIVED CARDIOMYOCYTES. HEART. 97:10-10. DOI.
  • Foldes G; Ali NN; Randi A; Starke R; Paschalaki K; Gatheral T; Harding SE; Mitchell JA. (2011). PATHOGEN SENSING PATHWAYS IN HUMAN STEM CELL-DERIVED ENDOTHELIAL CELLS. SHOCK. 36:4-4.
  • Jawad H; Boccaccini AR; Ali NN; Harding SE. (Sep 2011). Assessment of cellular toxicity of TiO2 nanoparticles for cardiac tissue engineering applications. NANOTOXICOLOGY. 5:372-380. DOI.
  • Földes G; Mioulane M; Wright JS; Liu AQ; Novak P; Merkely B; Gorelik J; Schneider MD; et alAli NN; Harding SE. (Feb 2011). Modulation of human embryonic stem cell-derived cardiomyocyte growth: a testbed for studying human cardiac hypertrophy?. J Mol Cell Cardiol. 50:367-376. DOI.
  • Jawad H; Boccaccini AR; Ali NN; Harding SE. (Sep 2011). Assessment of cellular toxicity of TiO2 nanoparticles for cardiac tissue engineering applications. Nanotoxicology. 5:372-380. DOI.
  • Stuckey DJ; Ishii H; Chen QZ; Boccaccini AR; Hansen U; Carr CA; Roether JA; Jawad H; et alTyler DJ; Ali NN; Clarke K; Harding SE. (Nov 2010). Magnetic resonance imaging evaluation of remodeling by cardiac elastomeric tissue scaffold biomaterials in a rat model of myocardial infarction. Tissue Eng Part A. 16:3395-3402. DOI.
  • Földes G; Liu A; Badiger R; Paul-Clark M; Moreno L; Lendvai Z; Wright JS; Ali NN; et alHarding SE; Mitchell JA. (2010). Innate immunity in human embryonic stem cells: comparison with adult human endothelial cells. PLoS One. 5:e10501. DOI.
  • Chen QZ; Ishii H; Thouas GA; Lyon AR; Wright JS; Blaker JJ; Chrzanowski W; Boccaccini AR; et alAli NN; Knowles JC; Harding SE. (May 2010). An elastomeric patch derived from poly(glycerol sebacate) for delivery of embryonic stem cells to the heart. BIOMATERIALS. 31:3885-3893. DOI.
  • Abdul Kadir SH; Ali NN; Mioulane M; Brito-Martins M; Abu-Hayyeh S; Foldes G; Moshkov AV; Williamson C; et alHarding SE; Gorelik J. (Sep 2009). Embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease. J Cell Mol Med. 13:3730-3741. DOI.
  • Gorelik J; Ali NN; Kadir SHSA; Lab M; Stojkovic P; Armstrong L; Sviderskaya EV; Negulyaev YA; et alKlenerman D; Bennett DC; Lako M; Harding SE; Stojkovic M; Korchev YE. (Dec 2008). Non-invasive Imaging of Stem Cells by Scanning Ion Conductance Microscopy: Future Perspective. TISSUE ENG PT C-METH. 14:311-318. DOI.
  • Jawad H; Lyon AR; Harding SE; Ali NN; Boccaccini AR. (Sep 2008). Myocardial tissue engineering. BRIT MED BULL. 87:31-47. DOI.
  • Földes G; Harding SE; Ali NN. (Oct 2008). Cardiomyocytes from embryonic stem cells: towards human therapy. Expert Opin Biol Ther. 8:1473-1483. DOI.
  • Chen QZ; Harding SE; Ali NN; Lyon AR; Boccaccini AR. (29 Feb 2008). Biomaterials in cardiac tissue engineering: Ten years of research survey. MAT SCI ENG R. 59:1-37. DOI.
  • Brito-Martins M; Harding SE; Ali NN. (Feb 2008). beta(1)- and beta(2)-adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non-failing adult human heart. Br J Pharmacol. 153:751-759. DOI.
  • Jawad H; Ali NN; Lyon AR; Chen QZ; Harding SE; Boccaccini AR. (Sep 2007). Myocardial tissue engineering: a review. J Tissue Eng Regen Med. 1:327-342. DOI.
  • Chen QZ; Bismarck A; Hansen U; Junaid S; Tran MQ; Harding SE; Ali NN; Boccaccini AR. (Jan 2008). Characterisation of a soft elastomer poly(glycerol sebacate) designed to match the mechanical properties of myocardial tissue. Biomaterials. 29:47-57. DOI.
  • Harding SE; Ali NN; Brito-Martins M; Gorelik J. (Feb 2007). The human embryonic stem cell-derived cardiomyocyte as a pharmacological model. Pharmacol Ther. 113:341-353. DOI.
  • Gorelik J; Ali NN; Shevchuk AI; Lab M; Williamson C; Harding SE; Korchev YE. (Apr 2006). Functional characterization of embryonic stem cell-derived cardiomyocytes using scanning ion conductance microscopy. Tissue Eng. 12:657-664. DOI.
  • Ali NN; Xu X; Brito-Martins M; Poole-Wilson PA; Harding SE; Fuller SJ. (Nov 2004). Beta-adrenoceptor subtype dependence of chronotropy in mouse embryonic stem cell-derived cardiomyocytes. Basic Res Cardiol. 99:382-391. DOI.
  • Rippon HJ; Ali NN; Polak JM; Bishop AE. (2004). Initial observations on the effect of medium composition on the differentiation of murine embryonic stem cells to alveolar type II cells. Cloning Stem Cells. 6:49-56. DOI.
  • Ali NN; Edgar AJ; Samadikuchaksaraei A; Timson CM; Romanska HM; Polak JM; Bishop AE. (Aug 2002). Derivation of type II alveolar epithelial cells from murine embryonic stem cells. Tissue Eng. 8:541-550. DOI.
  • Ali NN; Gilston V; Winyard PG. (29 Oct 1999). Activation of NF-kappaB in human osteoblasts by stimulators of bone resorption. FEBS Lett. 460:315-320.
  • Ali NN; Rowe J; Teich NM. (Apr 1996). Constitutive expression of non-bone/liver/kidney alkaline phosphatase in human osteosarcoma cell lines. J Bone Miner Res. 11:512-520. DOI.
  • Skerry TM; Suswillo R; el Haj AJ; Ali NN; Dodds RA; Lanyon LE. (May 1990). Load-induced proteoglycan orientation in bone tissue in vivo and in vitro. Calcif Tissue Int. 46:318-326.
  • Ali NN; Melhuish PB; Boyde A; Bennett A; Jones SJ. (Feb 1990). Parathyroid hormone, but not prostaglandin E2, changes the shape of osteoblasts maintained on bone in vitro. J Bone Miner Res. 5:115-121. DOI.
  • Delaisse JM; Boyde A; Maconnachie E; Ali NN; Sear CH; Eeckhout Y; Vaes G; Jones SJ. (1987). The effects of inhibitors of cysteine-proteinases and collagenase on the resorptive activity of isolated osteoclasts. Bone. 8:305-313.
  • Jones SJ; Ali NN; Boyde A. (1986). Survival and resorptive activity of chick osteoclasts in culture. Anat Embryol (Berl). 174:265-275.
  • Jones SJ; Boyde A; Ali NN; Maconnachie E. (1986). Variation in the sizes of resorption lacunae made in vitro. Scan Electron Microsc. 1571-1580.
  • Boyde A; Ali NN; Jones SJ. (1985). Optical and scanning electron microscopy in the single osteoclast resorption assay. Scan Electron Microsc. 1259-1271.
  • Boyde A; Ali NN; Jones SJ. (24 Mar 1984). Resorption of dentine by isolated osteoclasts in vitro. Br Dent J. 156:216-220.
  • Ali NN; Jones SJ; Boyde A. (1984). Monocyte-enriched cells on calcified tissues. Anat Embryol (Berl). 170:169-175.
  • Jones SJ; Boyde A; Ali NN. (1984). The resorption of biological and non-biological substrates by cultured avian and mammalian osteoclasts. Anat Embryol (Berl). 170:247-256.
  • Ali NN; Boyde A; Jones SJ. (1984). Motility and resorption: osteoclastic activity in vitro. Anat Embryol (Berl). 170:51-56.
  • Ali NN; Chambers TJ. (May 1983). The effect of prostaglandin I2 and 6a-Carba-PGI2 on the motility of isolated osteoclasts. Prostaglandins. 25:603-614.
  • Chambers TJ; Ali NN. (Mar 1983). Inhibition of osteoclastic motility by prostaglandins I2, E1, E2 and 6-oxo-E1. J Pathol. 139:383-397. DOI.
  • Ali NN; Harrison MA; Rowe J; Teich NM. (Nov 1993). Spectrum of osteoblastic differentiation in new cell lines derived from spontaneous murine osteosarcomas. Bone. 14:847-858.

Chapters in books

  • Ali, N N; Brito-Martins, M; Gorelik, J; Xu, X; Korchev, Y; Zhu, H; Poole-Wilson, P A; Fuller, S J; et alHarding, S E. Pharmacological characterisation of embryonic stem cell-derived cardiomyocyte cultures. In Stem Cells:Repair and Regeneration. 139-147. Habib (ed); N (ed); Gordon (ed); Y M (ed); Levicar (ed); N (ed); Jiao (ed); L (ed). Imperial College Press, London (2005).
  • Stevens, C R; Sahinoglu, T; Bhatt, B; Ali, N N; Blake, D R. The role of xanthine oxidase in disease. In Natural Antioxidants: Molecular mechanisms and health effects. 34-44. AOCS press, Champaign Illinois (1996).
  • Ali, N N; Auger, D W; Bennet, A; Edwards, D A; Harris, M. Effect of prostacyclin and its breakdown product 6-oxo-PGF1a on bone resorption in vitro. In Prostacyclin. 179-185. Vane (ed); R J (ed); Bergstrom (ed); S (ed). Raven Press, New York (1979).

Conferences

  • Reed DM; Foldes G; Gatheral T; Badiger RV; Wheeler-Jones CP; Ali NN; Harding SE; Mitchell JA. ENDOTHELIN-1 RELEASE FROM HUMAN EMBRYONIC STEM CELL DERIVED-ENDOTHELIAL CELLS (HESC-EC): COMPARISONS WITH HUMAN ENDOTHELIAL CELLS. 60:224-224. (Jun 2011).
  • Jawad H; El Fray M; Boccaccini AR; Harding SE; Wright JS; Chen QZ; Piegat A; Ali NN. Nanocomposite Elastomeric Biomaterials for Myocardial Tissue Engineering Using Embryonic Stem Cell-derived Cardiomyocytes. 12:B664-B674. (Dec 2010). DOI.
  • Mioulane M; Foldes G; Ali NN; Harding SE. Cardiomyocytes derived from human embryonic stem cells as an alternative model for cardiotoxicity and contractility studies. 87:S110-S110. (Jul 2010).
  • Foldes G; Mioulane M; Iqbal A; Schneider MD; Ali NN; Harding SE. Growth and proliferative activity of human embryonic stem cell-derived cardiomyocytes is modulated in a calcineurin-NFAT-dependent manner. 87:S111-S111. (Jul 2010).
  • Jawad H; Harding SE; Piegat A; El Fray M; Boccaccini AR; Ali NN. Myocardial tissue engineering using ES cell-derived cardiomyocytes and elastomeric polymers. Annual Tissue-Engineering-and-Regenerative-Medicine-International-Society-European-Chapter Meeting. 14:759-759. (May 2008).
  • Kadir SHSA; Ali NN; Abu-Hayyeh S; Harding SE; Williamson C; Gorelik J. The use of embryonic stem cell-derived cardiomyocytes as a model to study fetal arrhythmia related to maternal disease. 44:774-774. (Apr 2008). DOI.
  • Terracciano CMN; Payne J; Harding SE; Ali NN. Human embryonic stem cell-derived cardiomyocytes as a model for assessing HERG channel blockade. 94. (Feb 2008).
  • Chena QZ; Wright JS; Harding SE; Junaid S; Hansen U; Jawad H; Boccaccini AR; Ali NN. Heart tissue engineering using a novel elastomer and ES-derived cardiac cells. Conference of the Tissue-Engineering-and-Regenerative-Medicine-International-Society (TERMIS-EU). 13:1703-1703. (Jul 2007).
  • Ali NN; Xu X; Martins M; Poole-Wilson PA; Harding SE; Fuller SJ. Characterisation of beta-adrenoceptor responses in mouse embryonic stem cell-derived cardiomyocytes. 24th Annual Scientific Sessions of the European-Section of the International-Society-for-Heart-Research. 36:731-732. (May 2004).
  • Wright J; Ahmet S; Harding SE; Ali NN. Responses to endothelin in human embryonic stem cell-derived cardiomyocytes. 42:S88-S88. (Jun 2007). DOI.
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Internal Collaborators

External Collaborators

  • Dr. Ivana Barbaric
    (Centre for Stem Cell Biology, Sheffield University)
  • Dr. Lyn Healy
    Senior Stem cell Biologist (UK Stem Cell Bank)
  • Dr. Joseph Gold (Geron Corp., Menlo Park, USA)
  • Dr. Roland Fletcher and Dr. Jun Wheeler
    National Institute for Biological Standards and Control (NIBSC), UK
  • Professor Paul Townsend
    (University of Southampton)