Publications

Journals

Mahul-Mellier AL; Pazarentzos E; Datler C; Iwasawa R; Abuali G; Lin B; Grimm S. (16 Dec 2011). De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF. Cell Death Differ. DOI.
Lemarie A; Grimm S. (Sep 2011). Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer. ONCOGENE. 30:3985-4003. DOI.
Lin B; Huntley D; Abuali G; Langley SR; Sindelar G; Petretto E; Butcher S; Grimm S. (2011). Determining signalling nodes for apoptosis by a genetic high-throughput screen. PLoS One. 6:e25023. DOI.
Iwasawa R; Mahul-Mellier AL; Datler C; Pazarentzos E; Grimm S. (2 Feb 2011). Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J. 30:556-568. DOI.
Lemarie A; Huc L; Pazarentzos E; Mahul-Mellier AL; Grimm S. (Feb 2011). Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction. Cell Death Differ. 18:338-349. DOI.
Grimm S; Noteborn M. (Feb 2010). Anticancer genes: inducers of tumour-specific cell death signalling. Trends Mol Med. 16:88-96. DOI.
Lemarie A; Grimm S. (Jul 2009). Mutations in the heme b-binding residue of SDHC inhibit assembly of respiratory chain complex II in mammalian cells. Mitochondrion. 9:254-260. DOI.
Irshad S; Mahul-Mellier AL; Kassouf N; Lemarie A; Grimm S. (Jun 2009). Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers. Cell Death Differ. 16:890-898. DOI.
Grimm S; Lin B. (2009). Genetic cell culture screens reveal mitochondrial apoptosis control. Front Biosci. 14:1471-1478.
Grimm S; Brdiczka D. (May 2007). The permeability transition pore in cell death. Apoptosis. 12:841-855. DOI.
Brenner C; Grimm S. (Aug 2006). The permeability transition pore complex in cancer cell death. ONCOGENE. 25:4744-4756. DOI.
Kachel V; Sindelar G; Grimm S. (2006). High-throughput isolation of ultra-pure plasmid DNA by a robotic system. BMC Biotechnol. 6:9. DOI.
Grimm S. (Mar 2004). The art and design of genetic screens: mammalian culture cells. Nat Rev Genet. 5:179-189. DOI.
Schubert A; Grimm S. (1 Jan 2004). Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor. Cancer Res. 64:85-93.
Schoenfeld N; Bauer MK; Grimm S. (Jan 2004). The metastasis suppressor gene C33/CD82/KAI1 induces apoptosis through reactive oxygen intermediates. FASEB J. 18:158-160. DOI.
Gewies A; Grimm S. (20 Oct 2003). Cathepsin-B and cathepsin-L expression levels do not correlate with sensitivity of tumour cells to TNF-alpha-mediated apoptosis. Br J Cancer. 89:1574-1580. DOI.
Albayrak T; Scherhammer V; Schoenfeld N; Braziulis E; Mund T; Bauer MK; Scheffler IE; Grimm S. (Aug 2003). The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction. Mol Biol Cell. 14:3082-3096. DOI.
Albayrak T; Grimm S. (16 May 2003). A high-throughput screen for single gene activities: isolation of apoptosis inducers. Biochem Biophys Res Commun. 304:772-776.
Mund T; Gewies A; Schoenfeld N; Bauer MKA; Grimm S. (Feb 2003). Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum. FASEB J. 17:696-+. DOI.
Gewies A; Grimm S. (1 Feb 2003). UBP41 is a proapoptotic ubiquitin-specific protease. Cancer Res. 63:682-688.
Grimm S; Voss-Neudecker F. (2003). High-purity plasmid isolation using silica oxide. Methods Mol Biol. 235:83-87. DOI.
De Giorgi F; Lartigue L; Bauer MK; Schubert A; Grimm S; Hanson GT; Remington SJ; Youle RJ; et alIchas F. (Apr 2002). The permeability transition pore signals apoptosis by directing Bax translocation and multimerization. FASEB J. 16:607-609.
Grimm S; Kachel V. (Mar 2002). Robotic high-throughput assay for isolating apoptosis-inducing genes. BIOTECHNIQUES. 32:670-+.
De Giorgi F; Lartigue L; Bauer MKA; Schubert A; Grimm S; Hanson GT; Remington SJ; Youle RJ; et alIchas F. (Feb 2002). The permeability transition pore signals apoptosis by directing Bax translocation and multimerization. FASEB J. 16:607-+. DOI.
Neudecker F; Grimm S. (Jan 2000). High-throughput method for isolating plasmid DNA with reduced lipopolysaccharide content. Biotechniques. 28:107-109.
Bauer MK; Schubert A; Rocks O; Grimm S. (27 Dec 1999). Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis. J Cell Biol. 147:1493-1502.
Bauer MKA; Schubert A; Rocks O; Grimm S. (27 Dec 1999). Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis. J CELL BIOL. 147:1493-1501.
Weinstein EJ; Grimm S; Leder P. (22 Oct 1998). The oncogene heregulin induces apoptosis in breast epithelial cells and tumors. Oncogene. 17:2107-2113. DOI.
Grimm S; Weinstein EJ; Krane IM; Leder P. (19 Oct 1998). Neu differentiation factor (NDF), a dominant oncogene, causes apoptosis in vitro and in vivo. J Exp Med. 188:1535-1539.
Kelliher MA; Grimm S; Ishida Y; Kuo F; Stanger BZ; Leder P. (Mar 1998). The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity. 8:297-303.
Grimm S; Leder P. (17 Mar 1997). An apoptosis-inducing isoform of neu differentiation factor (NDF) identified using a novel screen for dominant, apoptosis-inducing genes. J Exp Med. 185:1137-1142.
Grimm S; Stanger BZ; Leder P. (1 Oct 1996). RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways. Proc Natl Acad Sci U S A. 93:10923-10927.
Foos G; Grimm S; Klempnauer KH. (Sep 1994). The chicken A-myb protein is a transcriptional activator. Oncogene. 9:2481-2488.
Foos G; Grimm S; Klempnauer KH. (Dec 1992). Functional antagonism between members of the myb family: B-myb inhibits v-myb-induced gene activation. EMBO J. 11:4619-4629.