Professor Steven Marston

Publications


Journals

  • Marston SB; Gautel M. (4 May 2012). Introducing a series of topical special issues of the Journal of Muscle Research and Cell Motility : MYBPC3 special issue editorial. J Muscle Res Cell Motil. DOI.
  • Jain RK; Jayawant S; Squier W; Muntoni F; Sewry CA; Manzur A; Quinlivan R; Lillis S; et alJungbluth H; Sparrow JC; Ravenscroft G; Nowak KJ; Memo M; Marston SB; Laing NG. (3 Apr 2012). Nemaline myopathy with stiffness and hypertonia associated with an ACTA1 mutation. Neurology. 78:1100-1103. DOI.
  • Marttila M; Lemola E; Wallefeld W; Memo M; Donner K; Laing NG; Marston S; Gronholm M; et alWallgren-Pettersson C. (15 Feb 2012). Abnormal actin binding of aberrant beta-tropomyosins is a molecular cause of muscle weakness in TPM2-related nemaline and cap myopathy. BIOCHEMICAL JOURNAL. 442:231-239. Author weblink DOI.
  • Vydyanath A; Gurnett CA; Marston S; Luther PK. (14 Mar 2012). Axial distribution of myosin binding protein-C is unaffected by mutations in human cardiac and skeletal muscle. J Muscle Res Cell Motil. DOI.
  • Marston S; Copeland O; Gehmlich K; Schlossarek S; Carrrier L. (5 Nov 2011). How do MYBPC3 mutations cause hypertrophic cardiomyopathy?. J Muscle Res Cell Motil. DOI.
  • Song W; Dyer E; Stuckey DJ; Copeland O; Leung MC; Bayliss C; Messer A; Wilkinson R; et alTremoleda JL; Schneider MD; Harding SE; Redwood CS; Clarke K; Nowak K; Monserrat L; Wells D; Marston SB. (5 Aug 2011). Molecular mechanism of the E99K mutation in cardiac actin (ACTC Gene) that causes apical hypertrophy in man and mouse. J Biol Chem. 286:27582-27593. DOI.
  • Marston SB. (Jun 2011). How do mutations in contractile proteins cause the primary familial cardiomyopathies?. J Cardiovasc Transl Res. 4:245-255. DOI.
  • Hoskins AC; Jacques A; Bardswell SC; McKenna WJ; Tsang V; dos Remedios CG; Ehler E; Adams K; et alJalilzadeh S; Avkiran M; Watkins H; Redwood C; Marston SB; Kentish JC. (1 Nov 2010). Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 49:737-745. DOI.
  • Copeland O; Sadayappan S; Messer AE; Steinen GJ; van der Velden J; Marston SB. (Dec 2010). Analysis of cardiac myosin binding protein-C phosphorylation in human heart muscle. J Mol Cell Cardiol. 49:1003-1011. DOI.
  • Copeland O; Nowak KJ; Laing NG; Ravenscroft G; Messer AE; Bayliss CR; Marston SB. (Sep 2010). Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts. J Muscle Res Cell Motil. 31:207-214. DOI.
  • Song W; Dyer E; Stuckey D; Leung MC; Memo M; Mansfield C; Ferenczi M; Liu K; et alRedwood C; Nowak K; Harding S; Clarke K; Wells D; Marston S. (Sep 2010). Investigation of a transgenic mouse model of familial dilated cardiomyopathy. J Mol Cell Cardiol. 49:380-389. DOI.
  • Messer AE; Gallon CE; McKenna WJ; Dos Remedios CG; Marston SB. (1 Dec 2009). The use of phosphate-affinity SDS-PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle. PROTEOMICS CLINICAL APPLICATIONS. 3:1371-1382. Author weblink DOI.
  • Dyer EC; Jacques AM; Hoskins AC; Ward DG; Gallon CE; Messer AE; Kaski JP; Burch M; et alKentish JC; Marston SB. (1 Sep 2009). Functional Analysis of a Unique Troponin C Mutation, GLY159ASP, that Causes Familial Dilated Cardiomyopathy, Studied in Explanted Heart Muscle. CIRCULATION-HEART FAILURE. 2:456-U101. Author weblink DOI.
  • Marston SB; Walker JW. (2009). Back to the future: new techniques show that forgotten phosphorylation sites are present in contractile proteins of the heart whilst intensively studied sites appear to be absent. J Muscle Res Cell Motil. 30:93-95. DOI.
  • Marston S; Copeland O; Jacques A; Livesey K; Tsang V; McKenna WJ; Jalilzadeh S; Carballo S; et alRedwood C; Watkins H. (31 Jul 2009). Evidence from human myectomy samples that MYBPC3 mutations cause hypertrophic cardiomyopathy through haploinsufficiency. Circ Res. 105:219-222. DOI.
  • Feng JJ; Ushakov DS; Ferenczi MA; Laing NG; Nowak KJ; Marston SB. (2009). Direct visualisation and kinetic analysis of normal and nemaline myopathy actin polymerisation using total internal reflection microscopy. J Muscle Res Cell Motil. 30:85-92. DOI.
  • Hamdani N; de Waard M; Messer AE; Boontje NM; Kooij V; van Dijk S; Versteilen A; Lamberts R; et alMerkus D; dos Remedios C; Duncker DJ; Borbely A; Papp Z; Paulus W; Stienen GJM; Marston SB; van der Velden J. (1 Dec 2008). Myofilament dysfunction in cardiac disease from mice to men. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 29:189-201. DOI.
  • Feng J-J; Marston S. (1 Jan 2009). Genotype-phenotype correlations in ACTA1 mutations that cause congenital myopathies. NEUROMUSCULAR DISORDERS. 19:6-16. Author weblink DOI.
  • Jacques A; Hoskins AC; Kentish JC; Marston SB. (2008). From genotype to phenotype: a longitudinal study of a patient with hypertrophic cardiomyopathy due to a mutation in the MYBPC3 gene. J Muscle Res Cell Motil. 29:239-246. DOI.
  • Marston S; El-Mezgueldi M. (2008). Role of tropomyosin in the regulation of contraction in smooth muscle. Adv Exp Med Biol. 644:110-123.
  • Marston SB; de Tombe PP. (1 Nov 2008). Troponin phosphorylation and myofilament Ca(2+) -sensitivity in heart failure: Increased or decreased?. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 45:603-607. Author weblink DOI.
  • Jacques AM; Copeland O; Messer AE; Gallon CE; King K; McKenna WJ; Tsang VT; Marston SB. (1 Aug 2008). Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 45:209-216. Author weblink DOI.
  • Marston S. (15 Jun 2008). How does genotype define phenotype? Microphysiology of a tropomyosin mutation in situ shows the limitations of reductionism. JOURNAL OF PHYSIOLOGY-LONDON. 586:2821-2821. Author weblink DOI.
  • Ansari S; Alahyan M; Marston SB; El-Mezgueldi M. (4 Jan 2008). Role of caldesmon in the Ca2+ regulation of smooth muscle thin filaments: evidence for a cooperative switching mechanism. J Biol Chem. 283:47-56. DOI.
  • Matsson H; Eason J; Bookwalter CS; Klar J; Gustavsson P; Sunnegardh J; Enell H; Jonzon A; et alVikkula M; Gutierrez I; Granados-Riveron J; Pope M; Bu'Lock F; Cox J; Robinson TE; Song F; Brook DJ; Marston S; Trybus KM; Dahl N. (1 Jan 2008). Alpha-cardiac actin mutations produce atrial septal defects. HUMAN MOLECULAR GENETICS. 17:256-265. Author weblink DOI.
  • Kasakov AS; Bukach OV; Seit-Nebi AS; Marston SB; Gusev NB. (1 Nov 2007). Effect of mutations in the beta 5-beta 7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11). FEBS JOURNAL. 274:5628-5642. Author weblink DOI.
  • Clarke NF; Ilkovski B; Cooper S; Valova VA; Robinson PJ; Nonaka I; Feng J-J; Marston S; et alNorth K. (1 Jun 2007). The pathogenesis of ACTA1-related congenital fiber type disproportion. ANNALS OF NEUROLOGY. 61:552-561. Author weblink DOI.
  • Mirza M; Robinson P; Kremneva E; Copeland O; Nikolaeva O; Watkins H; Levitsky D; Redwood C; et alEl-Mezgueldi M; Marston S. (4 May 2007). The effect of mutations in alpha-tropomyosin (E40K and E54K) that cause familial dilated cardiomyopathy on the regulatory mechanism of cardiac muscle thin filaments. J Biol Chem. 282:13487-13497. DOI.
  • Chernik IS; Seit-Nebi AS; Marston SB; Gusev NB. (1 Jan 2007). Small heat shock protein Hsp20 (HspB6) as a partner of 14-3-3 gamma. MOLECULAR AND CELLULAR BIOCHEMISTRY. 295:9-17. Author weblink DOI.
  • Messer AE; Jacques AM; Marston SB. (Jan 2007). Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure. J Mol Cell Cardiol. 42:247-259. DOI.
  • D'Amico A; Graziano C; Pacileo G; Petrini S; Nowak KJ; Boldrini R; Jacques A; Feng J-J; et alPorfirio B; Sewry CA; Santorelli FM; Limongelli G; Bertini E; Laing N; Marston SB. (1 Oct 2006). Fatal hypertrophic cardiomyopathy and nemaline myopathy associated with ACTA1 K336E mutation. NEUROMUSCULAR DISORDERS. 16:548-552. Author weblink DOI.
  • Kim MV; Kasakov AS; Seit-Nebi AS; Marston SB; Gusev NB. (1 Oct 2006). Structure and properties of K141E mutant of small heat shock protein HSP22 (HspB8, H11) that is expressed in human neuromuscular disorders. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 454:32-41. Author weblink DOI.
  • Alahyan M; Webb MR; Marston SB; El-Mezgueldi M. (14 Jul 2006). The mechanism of smooth muscle caldesmon-tropomyosin inhibition of the elementary steps of the actomyosin ATPase. J Biol Chem. 281:19433-19448. DOI.
  • Mirza M; Marston S; Willott R; Ashley C; Mogensen J; McKenna W; Robinson P; Redwood C; et alWatkins H. (5 Aug 2005). Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype. J Biol Chem. 280:28498-28506. DOI.
  • Holohan SJ; Marston SB. (Jun 2005). Force-velocity relationship of single actin filament interacting with immobilised myosin measured by electromagnetic technique. IEE Proc Nanobiotechnol. 152:113-120. DOI.
  • Gusev NB; Bukach OV; Marston SB. (1 Jun 2005). Structure, properties, and probable physiological role of small heat shock protein with molecular mass 20 kD (Hsp20, HspB6). BIOCHEMISTRY-MOSCOW. 70:629-637. Author weblink DOI.
  • Bukach OV; Marston SB; Gusev NB. (1 Jan 2005). Small heat shock protein with apparent molecular mass 20 kDa (Hsp20, HspB6) is not a genuine actin-binding protein. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 26:175-181. Author weblink DOI.
  • Chernik IS; Panasenko OO; Li Y; Marston SB; Gusev NB. (26 Nov 2004). pH-induced changes of the structure of small heat shock proteins with molecular mass 24/27 kDa (HspB1). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 324:1199-1203. DOI.
  • Kim MV; Seit-Nebi AS; Marston SB; Gusev NB. (19 Mar 2004). Some properties of human small heat shock protein Hsp22 (H11 or HspB8). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 315:796-801. Author weblink DOI.
  • Marston S; Mirza M; Abdulrazzak H; Sewry C. (Feb 2004). Functional characterisation of a mutant actin (Met132Val) from a patient with nemaline myopathy. Neuromuscul Disord. 14:167-174.
  • Bukach OV; Seit-Nebi AS; Marston SB; Gusev NB. (1 Jan 2004). Some properties of human small heat shock protein Hsp20 (HspB6). EUROPEAN JOURNAL OF BIOCHEMISTRY. 271:291-302. Author weblink DOI.
  • Marston SB; Redwood CS. (12 Dec 2003). Modulation of thin filament activation by breakdown or isoform switching of thin filament proteins: physiological and pathological implications. Circ Res. 93:1170-1178. DOI.
  • Panasenko OO; Kim MV; Marston SB; Gusev NB. (1 Mar 2003). Interaction of the small heat shock protein with molecular mass 25 kDa (hsp25) with actin. EUROPEAN JOURNAL OF BIOCHEMISTRY. 270:892-901. Author weblink DOI.
  • Ansari S; El-Mezgueldi M; Marston S. (2003). Cooperative inhibition of actin filaments in the absence of tropomyosin. J Muscle Res Cell Motil. 24:513-520.
  • Marston S. (2003). Random walks with thin filaments: application of in vitro motility assay to the study of actomyosin regulation. J Muscle Res Cell Motil. 24:149-156.
  • Panasenko OO; Seit Nebi A; Bukach OV; Marston SB; Gusev NB. (19 Nov 2002). Structure and properties of avian small heat shock protein with molecular weight 25 kDa. Biochim Biophys Acta. 1601:64-74.
  • Robinson P; Mirza M; Knott A; Abdulrazzak H; Willott R; Marston S; Watkins H; Redwood C. (25 Oct 2002). Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy. J Biol Chem. 277:40710-40716. DOI.
  • Gusev NB; Bogatcheva NV; Marston SB. (May 2002). Structure and properties of small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins. Biochemistry (Mosc). 67:511-519.
  • Knott A; Purcell I; Marston S. (Apr 2002). In vitro motility analysis of thin filaments from failing and non-failing human heart: troponin from failing human hearts induces slower filament sliding and higher Ca(2+) sensitivity. J Mol Cell Cardiol. 34:469-482. DOI.
  • Patchell VB; Vorotnikov AV; Gao Y; Low DG; Evans JS; Fattoum A; El-Mezgueldi M; Marston SB; et alLevine BA. (1 Apr 2002). Phosphorylation of the minimal inhibitory region at the C-terminus of caldesmon alters its structural and actin binding properties. Biochim Biophys Acta. 1596:121-130.
  • Burton D; Abdulrazzak H; Knott A; Elliott K; Redwood C; Watkins H; Marston S; Ashley C. (1 Mar 2002). Two mutations in troponin I that cause hypertrophic cardiomyopathy have contrasting effects on cardiac muscle contractility. Biochem J. 362:443-451.
  • Marston SB; Ingwall JS; Glueck SB. (2002). Calcium, contractions, and tropomyosin Focus on "divergent abnormal muscle relaxation by hypertrophic cardiomyopathy and nemaline myopathy mutant tropomyosins". Physiol Genomics. 9:57-58. DOI.
  • Gusev NB; Bogatcheva NV; Marston S. (2002). Structure and properties of small heat-shock proteins (sHsp) and their interactions with cytoskeletal proteins. Biokhimiia. 67:613-623.
  • Borovikov YS; Avrova SV; Vikhoreva NN; Vikhorev PG; Ermakov VS; Copeland O; Marston SB. (Dec 2001). C-terminal actin-binding sites of smooth muscle caldesmon switch actin between conformational states. Int J Biochem Cell Biol. 33:1151-1159.
  • Knott A; Purcell I; Marston S. (1 Jun 2001). Structural and functional properties of normal, failing and foetal human heart troponin. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 33:A60-A60. Author weblink DOI.
  • Goncharova EA; Shirinsky VP; Shevelev AY; Marston SB; Vorotnikov AV. (25 May 2001). Actomyosin cross-linking by caldesmon in non-muscle cells. FEBS Lett. 497:113-117.
  • Medvedeva MV; Djemuchadze DR; Watterson DM; Marston SB; Gusev NB. (12 Jan 2001). Replacement of Lys-75 of calmodulin affects its interaction with smooth muscle caldesmon. Biochim Biophys Acta. 1544:143-150.
  • Marston SB; Hodgkinson JL. (2001). Cardiac and skeletal myopathies: can genotype explain phenotype?. J Muscle Res Cell Motil. 22:1-4.
  • Abdulrazzak H; Knott A; Redwood C; Esposito G; Watkins H; Marston S. (1 Jan 2001). Investigation of troponin I mutations causing familial hypertrophic cardiomyopathy. BIOPHYSICAL JOURNAL. 80:263A-263A. Author weblink.
  • Bing W; Knott A; Marston SB. (15 Sep 2000). A simple method for measuring the relative force exerted by myosin on actin filaments in the in vitro motility assay: evidence that tropomyosin and troponin increase force in single thin filaments. BIOCHEMICAL JOURNAL. 350:693-699. Author weblink DOI.
  • Bing W; Knott A; Redwood C; Esposito G; Purcell I; Watkins H; Marston S. (Aug 2000). Effect of hypertrophic cardiomyopathy mutations in human cardiac muscle alpha -tropomyosin (Asp175Asn and Glu180Gly) on the regulatory properties of human cardiac troponin determined by in vitro motility assay. J Mol Cell Cardiol. 32:1489-1498. DOI.
  • Redwood C; Lohmann K; Bing W; Esposito GM; Elliott K; Abdulrazzak H; Knott A; Purcell I; et alMarston S; Watkins H. (9 Jun 2000). Investigation of a truncated cardiac troponin T that causes familial hypertrophic cardiomyopathy: Ca(2+) regulatory properties of reconstituted thin filaments depend on the ratio of mutant to wild-type protein. Circ Res. 86:1146-1152.
  • Notarianni G; Gusev N; Lafitte D; Hill TJ; Cooper HS; Derrick PJ; Marston SB. (2000). A novel Ca2+ binding protein associated with caldesmon in Ca2+-regulated smooth muscle thin filaments: evidence for a structurally altered form of calmodulin. J Muscle Res Cell Motil. 21:537-549.
  • Gao Y; Patchell VB; Huber PAJ; Copeland O; El-Mezgueldi M; Fattoum A; Calas B; Thorsted PB; et alMarston SB; Levine BA. (23 Nov 1999). The interface between caldesmon domain 4b and subdomain 1 of actin studied by nuclear magnetic resonance spectroscopy. BIOCHEMISTRY. 38:15459-15469. Author weblink DOI.
  • Purcell IF; Bing W; Marston SB. (Sep 1999). Functional analysis of human cardiac troponin by the in vitro motility assay: comparison of adult, foetal and failing hearts. Cardiovasc Res. 43:884-891.
  • Krymsky MA; Chibalina MV; Shirinsky VP; Marston SB; Vorotnikov AV. (11 Jun 1999). Evidence against the regulation of caldesmon inhibitory activity by p42/p44(erk) mitogen-activated protein kinase in vitro and demonstration of another caldesmon kinase in intact gizaard smooth muscle. FEBS LETTERS. 452:254-258. Author weblink DOI.
  • Burton DJ; Marston SB. (Jan 1999). Control of shortening speed in single guinea-pig taenia coli smooth muscle cells by Ca2+, phosphorylation and caldesmon. Pflugers Arch. 437:267-275.
  • Marston S; Burton D; Copeland O; Fraser I; Gao Y; Hodgkinson J; Huber P; Levine B; et alel-Mezgueldi M; Notarianni G. (Dec 1998). Structural interactions between actin, tropomyosin, caldesmon and calcium binding protein and the regulation of smooth muscle thin filaments. Acta Physiol Scand. 164:401-414.
  • Bing W; Razzaq A; Sparrow J; Marston S. (12 Jun 1998). Tropomyosin and troponin regulation of wild type and E93K mutant actin filaments from Drosophila flight muscle. Charge reversal on actin changes actin-tropomyosin from on to off state. J Biol Chem. 273:15016-15021.
  • El-Mezgueldi M; Copeland O; Fraser ID; Marston SB; Huber PA. (1 Jun 1998). Characterization of the functional properties of smooth muscle caldesmon domain 4a: evidence for an independent inhibitory actin-tropomyosin binding domain. Biochem J. 332 ( Pt 2):395-401.
  • Huber PA; Gao Y; Fraser ID; Copeland O; EL-Mezgueldi M; Slatter DA; Keane NE; Marston SB; et alLevine BA. (24 Feb 1998). Structure-activity studies of the regulatory interaction of the 10 kilodalton C-terminal fragment of caldesmon with actin and the effect of mutation of caldesmon residues 691-696. Biochemistry. 37:2314-2326. DOI.
  • Huber PA; Levine BA; Copeland O; Marston SB; El-Mezgueldi M. (13 Feb 1998). Characterisation of the effects of mutation of the caldesmon sequence 691glu-trp-leu-thr-lys-thr696 to pro-gly-his-tyr-asn-asn on caldesmon-calmodulin interaction. FEBS Lett. 423:93-97.
  • Polyakov AA; Huber PAJ; Marston SB; Gusev NB. (30 Jan 1998). Interaction of isoforms of S100 protein with smooth muscle caldesmon. FEBS LETTERS. 422:235-239. DOI.
  • Vorotnikov AV; Marston SB; Huber PAJ. (15 Nov 1997). Location and functional characterization of myosin contact sites in smooth-muscle caldesmon. BIOCHEMICAL JOURNAL. 328:211-218. Author weblink.
  • Hodgkinson JL; el-Mezgueldi M; Craig R; Vibert P; Marston SB; Lehman W. (17 Oct 1997). 3-D image reconstruction of reconstituted smooth muscle thin filaments containing calponin: visualization of interactions between F-actin and calponin. J Mol Biol. 273:150-159. DOI.
  • Bing W; Fraser ID; Marston SB. (15 Oct 1997). Troponin I and troponin T interact with troponin C to produce different Ca2+-dependent effects on actin-tropomyosin filament motility. Biochem J. 327 ( Pt 2):335-340.
  • Bing W; Redwood CS; Purcell IF; Esposito G; Watkins H; Marston SB. (30 Jul 1997). Effects of two hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on Ca2+ regulation of thin filament motility. Biochem Biophys Res Commun. 236:760-764. DOI.
  • Hodgkinson JL; Marston SB; Craig R; Vibert P; Lehman W. (Jun 1997). Three-dimensional image reconstruction of reconstituted smooth muscle thin filaments: effects of caldesmon. Biophys J. 72:2398-2404. DOI.
  • Medvedeva MV; Kolobova EA; Huber PAJ; Fraser IDC; Marston SB; Gusev NB. (15 May 1997). Mapping of contact sites in the caldesmon-calmodulin complex. BIOCHEMICAL JOURNAL. 324:255-262. Author weblink.
  • Fraser ID; Copeland O; Bing W; Marston SB. (6 May 1997). The inhibitory complex of smooth muscle caldesmon with actin and tropomyosin involves three interacting segments of the C-terminal domain 4. Biochemistry. 36:5483-5492. DOI.
  • EL-Mezgueldi M; Marston SB. (8 Nov 1996). The effects of smooth muscle calponin on the strong and weak myosin binding sites of F-actin. J Biol Chem. 271:28161-28167.
  • Hnath EJ; Wang CLA; Huber PAJ; Marston SB; Phillips GN. (1 Oct 1996). Affinity and structure of complexes of tropomyosin and caldesmon domains. BIOPHYSICAL JOURNAL. 71:1920-1933. Author weblink.
  • Marston SB; Fraser ID; Bing W; Roper G. (Aug 1996). A simple method for automatic tracking of actin filaments in the motility assay. J Muscle Res Cell Motil. 17:497-506.
  • Huber PAJ; ElMezgueldi M; Grabarek Z; Slatter DA; Levine BA; Marston SB. (1 Jun 1996). Multiple-sited interaction of caldesmon with Ca2(+)-calmodulin. BIOCHEMICAL JOURNAL. 316:413-420.
  • Huber PA; Fraser ID; Marston SB. (1 Dec 1995). Location of smooth-muscle myosin and tropomyosin binding sites in the C-terminal 288 residues of human caldesmon. Biochem J. 312 ( Pt 2):617-625.
  • Fraser ID; Marston SB. (25 Aug 1995). In vitro motility analysis of smooth muscle caldesmon control of actin-tropomyosin filament movement. J Biol Chem. 270:19688-19693.
  • Fraser ID; Marston SB. (7 Apr 1995). In vitro motility analysis of actin-tropomyosin regulation by troponin and calcium. The thin filament is switched as a single cooperative unit. J Biol Chem. 270:7836-7841.
  • Hodgkinson JL; Newman TM; Marston SB; Severs NJ. (Mar 1995). The structure of the contractile apparatus in ultrarapidly frozen smooth muscle: freeze-fracture, deep-etch, and freeze-substitution studies. J Struct Biol. 114:93-104. DOI.
  • Marston S. (Feb 1995). Ca(2+)-dependent protein switches in actomyosin based contractile systems. Int J Biochem Cell Biol. 27:97-108.
  • Payne AM; Yue P; Pritchard K; Marston SB. (15 Jan 1995). Caldesmon mRNA splicing and isoform expression in mammalian smooth-muscle and non-muscle tissues. Biochem J. 305 ( Pt 2):445-450.
  • Marston SB; Fraser ID; Huber PA. (23 Dec 1994). Smooth muscle caldesmon controls the strong binding interaction between actin-tropomyosin and myosin. J Biol Chem. 269:32104-32109.
  • Reckless J; Fleetwood G; Tilling L; Huber PA; Marston SB; Pritchard K. (Nov 1994). Changes in the caldesmon isoform content and intimal thickening in the rabbit carotid artery induced by a silicone elastomer collar. Arterioscler Thromb. 14:1837-1845.
  • Marston SB; Fraser ID; Huber PA; Pritchard K; Gusev NB; Torok K. (18 Mar 1994). Location of two contact sites between human smooth muscle caldesmon and Ca(2+)-calmodulin. J Biol Chem. 269:8134-8139.
  • Huber PA; Redwood CS; Avent ND; Tanner MJ; Marston SB. (Aug 1993). Identification of functioning regulatory sites and a new myosin binding site in the C-terminal 288 amino acids of caldesmon expressed from a human clone. J Muscle Res Cell Motil. 14:385-391.
  • Redwood CS; Marston SB; Gusev NB. (19 Jul 1993). The functional effects of mutations Thr673-->Asp and Ser702-->Asp at the Pro-directed kinase phosphorylation sites in the C-terminus of chicken gizzard caldesmon. FEBS Lett. 327:85-89.
  • Marston SB; Redwood CS. (15 Jun 1993). The essential role of tropomyosin in cooperative regulation of smooth muscle thin filament activity by caldesmon. J Biol Chem. 268:12317-12320.
  • Redwood CS; Marston SB. (25 May 1993). Binding and regulatory properties of expressed functional domains of chicken gizzard smooth muscle caldesmon. J Biol Chem. 268:10969-10976.
  • Pritchard K; Marston SB. (29 Jan 1993). The Ca(2+)-sensitizing component of smooth muscle thin filaments: properties of regulatory factors that interact with caldesmon. Biochem Biophys Res Commun. 190:668-673. DOI.
  • Marston SB; Redwood CS. (25 Aug 1992). Inhibition of actin-tropomyosin activation of myosin MgATPase activity by the smooth muscle regulatory protein caldesmon. J Biol Chem. 267:16796-16800.
  • Pinter K; Marston SB. (6 Jul 1992). Phosphorylation of vascular smooth muscle caldesmon by endogenous kinase. FEBS Lett. 305:192-196.
  • Marston S; Pinter K; Bennett P. (Apr 1992). Caldesmon binds to smooth muscle myosin and myosin rod and crosslinks thick filaments to actin filaments. J Muscle Res Cell Motil. 13:206-218.
  • Marston SB. (4 Nov 1991). Properties of calponin isolated from sheep aorta thin filaments. FEBS Lett. 292:179-182.
  • Marston SB; Redwood CS. (1 Oct 1991). The molecular anatomy of caldesmon. Biochem J. 279 ( Pt 1):1-16.
  • Pritchard K; Marston SB. (1 Aug 1991). Ca(2+)-dependent regulation of vascular smooth-muscle caldesmon by S.100 and related smooth-muscle proteins. Biochem J. 277 ( Pt 3):819-824.
  • Marston S. (1 Dec 1990). Stoichiometry and stability of caldesmon in native thin filaments from sheep aorta smooth muscle. Biochem J. 272:305-310.
  • Redwood CS; Marston SB; Bryan J; Cross RA; Kendrick-Jones J. (17 Sep 1990). The functional properties of full length and mutant chicken gizzard smooth muscle caldesmon expressed in Escherichia coli. FEBS Lett. 270:53-56.
  • Marston SB. (1 Apr 1989). A tight-binding interaction between smooth-muscle native thin filaments and heavy meromyosin in the presence of MgATP. Biochem J. 259:303-306.
  • Marston SB. (Apr 1989). What is latch? New ideas about tonic contraction in smooth muscle. J Muscle Res Cell Motil. 10:97-100.
  • Pritchard K; Marston SB. (1 Feb 1989). Ca2+-calmodulin binding to caldesmon and the caldesmon-actin-tropomyosin complex. Its role in Ca2+ regulation of the activity of synthetic smooth-muscle thin filaments. Biochem J. 257:839-843.
  • Marston S. (Jan 1989). Calcium ion-dependent regulation of uterine smooth muscle thin filaments by caldesmon. Am J Obstet Gynecol. 160:252-257.
  • Taggart MJ; Marston SB. (19 Dec 1988). The effects of vascular smooth muscle caldesmon on force production by 'desensitised' skeletal muscle fibres. FEBS Lett. 242:171-174.
  • Marston S. (26 Sep 1988). Aorta caldesmon inhibits actin activation of thiophosphorylated heavy meromyosin Mg2+-ATPase activity by slowing the rate of product release. FEBS Lett. 238:147-150.
  • Marston SB; Redwood CS; Lehman W. (30 Aug 1988). Reversal of caldesmon function by anti-caldesmon antibodies confirms its role in the calcium regulation of vascular smooth muscle thin filaments. Biochem Biophys Res Commun. 155:197-202.
  • Marston S; Pritchard K; Redwood C; Taggart M. (Aug 1988). Ca2+ regulation of the thin filaments: biochemical mechanism and physiological role. Biochem Soc Trans. 16:494-497.
  • MARSTON S; SMITH CW; WALTERS M. (1 Jan 1982). AN IMPROVED PREPARATION OF AORTA SMOOTH-MUSCLE THIN-FILAMENTS. JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 3:476-476. Author weblink.
  • WALTERS M; MARSTON SB. (1 Jan 1981). PHOSPHORYLATION OF THE CALCIUM ION-REGULATED THIN-FILAMENTS FROM VASCULAR SMOOTH-MUSCLE - A NEW REGULATORY MECHANISM. BIOCHEMICAL JOURNAL. 197:127-139. Author weblink.
  • MARSTON SB; TREVETT RM; WALTERS M. (1 Jan 1980). CALCIUM ION-REGULATED THIN-FILAMENTS FROM VASCULAR SMOOTH-MUSCLE. BIOCHEMICAL JOURNAL. 185:355-365. Author weblink.
  • MARSTON SB; TAYLOR EW. (1 Jan 1980). COMPARISON OF THE MYOSIN AND ACTOMYOSIN ATPASE MECHANISMS OF THE 4 TYPES OF VERTEBRATE MUSCLES. JOURNAL OF MOLECULAR BIOLOGY. 139:573-600. Author weblink DOI.
  • MARSTON SB; WALTERS M. (1 Jan 1980). PHOSPHORYLATION OF THIN-FILAMENTS REGULATES VASCULAR SMOOTH-MUSCLE ACTOMYOSIN ATPASE ACTIVITY. CELL BIOLOGY INTERNATIONAL REPORTS. 4:799-799. Author weblink DOI.
  • MARSTON SB; TREGEAR RT; RODGER CD; CLARKE ML. (1 Jan 1979). COUPLING BETWEEN THE ENZYMATIC SITE OF MYOSIN AND THE MECHANICAL OUTPUT OF MUSCLE. JOURNAL OF MOLECULAR BIOLOGY. 128:111-126. Author weblink DOI.
  • TREGEAR RT; MARSTON SB. (1 Jan 1979). CROSSBRIDGE THEORY. ANNUAL REVIEW OF PHYSIOLOGY. 41:723-736. Author weblink DOI.
  • MARSTON S. (1 Jan 1978). COMPLEX KINETICS OF ACTIN-SUBFRAGMENT-1 ATPASE AT LOW-TEMPERATURE. FEBS LETTERS. 92:147-151. Author weblink DOI.
  • MARSTON SB; TAYLOR EW. (1 Jan 1978). MECHANISM OF MYOSIN AND ACTOMYOSIN ATPASE IN CHICKEN GIZZARD SMOOTH-MUSCLE. FEBS LETTERS. 86:167-170. DOI.
  • TAYLOR EW; MARSTON SB. (1 Jan 1977). COMPARISON OF MYOSIN AND ACTOMYOSIN ATPASE CYCLES OF FAST AND SLOW MUSCLES. FEDERATION PROCEEDINGS. 36:830-830. Author weblink.
  • MARSTON SB; RODGER CD; TREGEAR RT. (1 Jan 1976). CHANGES IN MUSCLE CROSSBRIDGES WHEN BETA, GAMMA-IMIDO-ATP BINDS TO MYOSIN. JOURNAL OF MOLECULAR BIOLOGY. 104:263-276. Author weblink DOI.
  • MARSTON S; TREGEAR RT. (1 Jan 1974). CALCIUM-BINDING AND ACTIVATION OF FIBRILLAR INSECT FLIGHT-MUSCLE. BIOCHIMICA ET BIOPHYSICA ACTA. 347:311-318. Author weblink DOI.
  • MARSTON SB; TREGEAR RT. (1 Jan 1974). NUCLEOTIDE BINDING TO MYOSIN IN CALCIUM ACTIVATED MUSCLE. BIOCHIMICA ET BIOPHYSICA ACTA. 333:581-584. Author weblink DOI.
  • MARSTON S. (1 Jan 1973). NUCLEOTIDE COMPLEXES OF MYOSIN IN GLYCEROL-EXTRACTED MUSCLE FIBERS. BIOCHIMICA ET BIOPHYSICA ACTA. 305:397-412. DOI.

Chapters in books

  • El Mezgueldi M; Marston SB. Caldesmon. 428-430. (2001).
Share this on Delicious
Tweet this
Digg this
Stumble this
Share this on Facebook