Prof Simon A McG Thom MD FRCP

Publications


Journals

  • Zhang X; Luckham PF; Hughes AD; Thom S; Xu XY. (15 Dec 2011). Development of lysolipid-based thermosensitive liposomes for delivery of high molecular weight proteins. Int J Pharm. 421:291-292. DOI.
  • Khamis RY; Johns M; Thom S; Mayet J; McConnell E; Stanton A; Jeyapalan S; Annon S; et alWrigley S; Hughes A; Haskard DO. (Oct 2011). IGG ANTI-MALONEDIALDEHYDE-LDL ANTIBODIES ARE ASSOCIATED WITH LOW RISK OF CARDIOVASCULAR EVENTS IN A SUBSTUDY OF THE ANGLO-SCANDINAVIAN CARDIAC OUTCOMES TRIAL (ASCOT), AND ARE UNRELATED TO LDL, CRP LEVELS AND STATIN TREATMENT. HEART. 97:5-5. DOI.
  • McCarthy N; Vangjeli C; Surendran P; Treumann A; Rooney C; Ho E; Sever P; Thom S; et alHughes A; Munroe P; Howard P; Johnson T; Caulfield MJ; Shields D; O'Brien E; Fitzgerald D; Stanton A. (Oct 2011). PPARGC1 beta is a genetic determinant of the cardiovascular risk factor, Thromboxane A2-an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) sub-study. J HUM HYPERTENS. 25:625-625.
  • Sever PS; Poulter NR; Chang CL; Hingorani A; Thom SA; Hughes AD; Welsh P; Sattar N; et alon behalf of the ASCOT Investigators. (28 Jul 2011). Evaluation of C-reactive protein prior to and on-treatment as a predictor of benefit from atorvastatin: observations from the Anglo-Scandinavian Cardiac Outcomes Trial. Eur Heart J. DOI.
  • Bathula R; Hughes AD; Panerai RB; Potter JF; McG Thom SA; Tillin T; Shore AC; Hale R; et alChambers J; Kooner J; Chaturvedi N. (Dec 2011). South Asians have adverse cerebrovascular haemodynamics, despite equivalent blood pressure, compared with Europeans. This is due to their greater hyperglycaemia. Int J Epidemiol. 40:1490-1498. DOI.
  • Rodgers A; Patel A; Berwanger O; Bots M; Grimm R; Grobbee DE; Jackson R; Neal B; et alNeaton J; Poulter N; Rafter N; Raju PK; Reddy S; Thom S; Vander Hoorn S; Webster R; PILL Collaborative Grp. (25 May 2011). An International Randomised Placebo-Controlled Trial of a Four-Component Combination Pill ("Polypill") in People with Raised Cardiovascular Risk. PLOS ONE. 6. DOI.
  • Starmans-Kool MJ; Stanton AV; Xu YY; McG Thom SA; Parker KH; Hughes AD. (Feb 2011). High dietary salt intake increases carotid blood pressure and wave reflection in normotensive healthy young men. J Appl Physiol. 110:468-471. DOI.
  • Sofat R; Casas JP; Kumari M; Talmud PJ; Ireland H; Kivimaki M; Marmot M; Hughes AD; et alThom S; Ebrahim S; Whittaker JC; Smeeth L; Lawlor DA; Humphries SE; Hingorani AD. (Nov 2010). Genetic variation in complement factor H and risk of coronary heart disease: Eight new studies and a meta-analysis of around 48,000 individuals. ATHEROSCLEROSIS. 213:184-190. DOI.
  • Witt NW; Chapman N; Thom SA; Stanton AV; Parker KH; Hughes AD. (Sep 2010). A novel measure to characterise optimality of diameter relationships at retinal vascular bifurcations. Artery Res. 4:75-80. DOI.
  • Ariff BB; Glor FP; Crowe L; Xu XY; Vennart W; Firmin DN; Thom SM; Hughes AD. (Dec 2010). Carotid artery hemodynamics: observing patient-specific changes with amlodipine and lisinopril by using MR imaging computation fluid dynamics. Radiology. 257:662-669. DOI.
  • Manisty C; Mayet J; Tapp RJ; Parker KH; Sever P; Poulter NR; Thom SA; Hughes AD; et alASCOT Investigators. (29 Jun 2010). Wave reflection predicts cardiovascular events in hypertensive individuals independent of blood pressure and other cardiovascular risk factors: an ASCOT (Anglo-Scandinavian Cardiac Outcome Trial) substudy. J Am Coll Cardiol. 56:24-30. DOI.
  • Bathula R; Hughes AD; Panerai R; Potter J; Thom SA; Francis DP; Shore AC; Kooner J; et alChaturvedi N. (Oct 2010). Indian Asians have poorer cardiovascular autonomic function than Europeans: this is due to greater hyperglycaemia and may contribute to their greater risk of heart disease. Diabetologia. 53:2120-2128. DOI.
  • Justesen BL; Mistry P; Chaturvedi N; Thom SA; Witt N; Kohler D; Hughes AD; Sjolie AK. (Jun 2010). Retinal arterioles have impaired reactivity to hyperoxia in type 1 diabetes. ACTA OPHTHALMOL. 88:453-457. DOI.
  • Tapp RJ; Sharp A; Stanton AV; O'Brien E; Chaturvedi N; Poulter NR; Sever PS; Thom SA; et alHughes AD; Mayet J; ASCOT Investigators. (27 Apr 2010). Differential effects of antihypertensive treatment on left ventricular diastolic function: an ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) substudy. J Am Coll Cardiol. 55:1875-1881. DOI.
  • Wimalasundera RC; Wijetunge S; Thom SM; Regan L; Hughes AD. (Mar 2010). Impaired recovery of intracellular calcium and force after activation in isolated myometrial and subcutaneous resistance arteries from women with preeclampsia. J Hypertens. 28:568-574. DOI.
  • Sharp AS; Tapp RJ; Thom SA; Francis DP; Hughes AD; Stanton AV; Zambanini A; O'Brien E; et alChaturvedi N; Lyons S; Byrd S; Poulter NR; Sever PS; Mayet J; ASCOT Investigators. (Mar 2010). Tissue Doppler E/E' ratio is a powerful predictor of primary cardiac events in a hypertensive population: an ASCOT substudy. Eur Heart J. 31:747-752. DOI.
  • Liu D; Wood NB; Witt N; Hughes AD; Thom SA; Xu XY. (Nov 2009). Computational analysis of oxygen transport in the retinal arterial network. Curr Eye Res. 34:945-956. DOI.
  • Manisty C; Mayet J; Tapp RJ; Sever PS; Poulter N; McG Thom SA; Hughes AD; ASCOT Investigators. (Nov 2009). Atorvastatin treatment is associated with less augmentation of the carotid pressure waveform in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT). Hypertension. 54:1009-1013. DOI.
  • Manisty CH; Zambanini A; Parker KH; Davies JE; Francis DP; Mayet J; McG Thom SA; Hughes AD; et alAnglo-Scandinavian Cardiac Outcome Trial Investigators. (Oct 2009). Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian Cardiac Outcome Trial substudy. Hypertension. 54:724-730. DOI.
  • Mahal S; Strain WD; Martinez-Perez ME; Thom SA; Chaturvedi N; Hughes AD. (Sep 2009). Comparison of the retinal microvasculature in European and African-Caribbean people with diabetes. Clin Sci (Lond). 117:229-236. DOI.
  • Thom S; Stettler C; Stanton A; Witt N; Tapp R; Chaturvedi N; Allemann S; Mayet J; et alSever P; Poulter N; O'Brien E; Hughes A. (Aug 2009). Differential Effects of Antihypertensive Treatment on the Retinal Microcirculation An Anglo-Scandinavian Cardiac Outcomes Trial Substudy. HYPERTENSION. 54:405-408. DOI.
  • Stettler C; Witt N; Tapp RJ; Thom S; Allemann S; Tillin T; Stanton A; O'Brien E; et alPoulter N; Gallimore JR; Hughes AD; Chaturvedi N. (Jun 2009). Serum Amyloid A, C-Reactive Protein, and Retinal Microvascular Changes in Hypertensive Diabetic and Nondiabetic Individuals An Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy. DIABETES CARE. 32:1098-1100. DOI.
  • Dolan E; Stanton AV; Thom S; Caulfield M; Atkins N; McInnes G; Collier D; Dicker P; et alO'Brien E; ASCOT Investigators. (Apr 2009). Ambulatory blood pressure monitoring predicts cardiovascular events in treated hypertensive patients--an Anglo-Scandinavian cardiac outcomes trial substudy. J Hypertens. 27:876-885. DOI.
  • Torii R; Wood NB; Hadjiloizou N; Dowsey AW; Wright AR; Hughes AD; Davies J; Francis DP; et alMayet J; Yang GZ; Thom SA; Xu XY. (Mar 2009). Stress phase angle depicts differences in coronary artery hemodynamics due to changes in flow and geometry after percutaneous coronary intervention. Am J Physiol Heart Circ Physiol. 296:H765-H776. DOI.
  • Diller GP; Wasan BS; Thom SA; Foale RA; Hughes AD; Francis DP; Mayet J. (Feb 2009). Evidence of improved regional myocardial function in patients with chronic stable angina and apparent normal ventricular function--a tissue Doppler study before and after percutaneous coronary intervention. J Am Soc Echocardiogr. 22:177-182. DOI.
  • Sun N; Torii R; Wood NB; Hughes AD; Thom SA; Xu XY. (Feb 2009). Computational modeling of LDL and albumin transport in an in vivo CT image-based human right coronary artery. J Biomech Eng. 131:021003. DOI.
  • Williams B; Lacy PS; Cruickshank JK; Collier D; Hughes AD; Stanton A; Thom S; Thurston H; et alCAFE and ASCOT Investigators. (6 Jan 2009). Impact of statin therapy on central aortic pressures and hemodynamics: principal results of the Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) Study. Circulation. 119:53-61. DOI.
  • Hughes AD; Wong TY; Witt N; Evans R; Thom SA; Klein BE; Chaturvedi N; Klein R. (Feb 2009). Determinants of retinal microvascular architecture in normal subjects. Microcirculation. 16:159-166. DOI.
  • Sun N; Leung JH; Wood NB; Hughes AD; Thom SA; Cheshire NJ; Xu XY. (Jan 2009). Computational analysis of oxygen transport in a patient-specific model of abdominal aortic aneurysm with intraluminal thrombus. BRIT J RADIOL. 82:S18-S23. DOI.
  • Torii R; Keegan J; Wood NB; Dowsey AW; Hughes AD; Yang GZ; Firmin DN; Thom SAM; et alXu XY. (Jan 2009). The effect of dynamic vessel motion on haemodynamic parameters in the right coronary artery: a combined MR and CFD study. BRIT J RADIOL. 82:S24-S32. DOI.
  • Tan FPP; Soloperto G; Bashford S; Wood NB; Thom S; Hughes A; Xu XY. (Dec 2008). Analysis of Flow Disturbance in a Stenosed Carotid Artery Bifurcation Using Two-Equation Transitional and Turbulence Models. J BIOMECH ENG-T ASME. 130. DOI.
  • Bathula R; Hughes AD; Thom S; Panerai R; Potter J; Francis DP; Shore A; Kooner J; et alChaturvedi N. (Oct 2008). Mechanisms for the greater impact of diabetes on stroke risk in Indian Asians compared to Europeans. J HUM HYPERTENS. 22:720-720.
  • Sharp A; Tapp R; Francis DP; McG Thom SA; Hughes AD; Stanton AV; Zambanini A; Chaturvedi N; et alByrd S; Poulter NR; Sever PS; Mayet J. (16 Sep 2008). Ethnicity and left ventricular diastolic function in hypertension an ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) substudy. J Am Coll Cardiol. 52:1015-1021. DOI.
  • Stettler C; Witt N; Tapp R; Stanton A; Thom S; Allemann S; Tillin T; Hughes AD; et alChaturvedi N. (Sep 2008). Retinal microvascular changes and risk of coronary heart disease in hypertensive diabetic and non-diabetic individuals: an ASCOT substudy. DIABETOLOGIA. 51:S16-S16.
  • Hughes AD; Stanton AV; Jabbar AS; Chapman N; Martinez-Perez ME; McG Thom SA. (Aug 2008). Effect of antihypertensive treatment on retinal microvascular changes in hypertension. J Hypertens. 26:1703-1707. DOI.
  • Downie SP; Raynor SM; Firmin DN; Wood NB; Thom SA; Hughes AD; Parker KH; Wolfe JHN; et alXu XY. (May 2008). Effects of elastic compression stockings on wall shear stress in deep and superficial veins of the calf. AM J PHYSIOL-HEART C. 294:H2112-H2120. DOI.
  • Tapp RJ; Witt N; Chaturvedi N; Evans R; Thom SA; Hughes AD; Ness A; Williams C. (Apr 2008). Low birth weight and retinal vascular caliber in young children - Reply. PEDIATRICS. 121:863-863. DOI.
  • Tillin T; Dhutia H; Chambers J; Malik I; Coady E; Mayet J; Wright AR; Kooner J; et alShore A; Thom S; Chaturvedi N; Hughes A. (13 Oct 2008). South Asian men have different patterns of coronary artery disease when compared with European men. INT J CARDIOL. 129:406-413. DOI.
  • Tapp RJ; Williams C; Witt N; Chaturvedi N; Evans R; Thom SA; Hughes AD; Ness A. (Nov 2007). Impact of size at birth on the microvasculature: the Avon Longitudinal Study of Parents and Children. Pediatrics. 120:e1225-e1228. DOI.
  • Dowsey AW; Keegan J; Lerotic M; Thom S; Firmin D; Yang GZ. (Oct 2007). Motion-compensated MR valve imaging with COMB tag tracking and super-resolution enhancement. MED IMAGE ANAL. 11:478-491.
  • Dotsenko O; Chaturvedi N; Thom SA; Wright AR; Mayet J; Shore A; Schalkwijk C; Hughes AD. (Oct 2007). Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men. J Thromb Haemost. 5:2036-2042. DOI.
  • Malaweera A; Davies JE; Hadjiloizou N; Manisty C; Zambanini A; Aguado-Sierra J; Thom SA; Parker KH; et alFrancis DP; Mayet J; Hughes AD. (Oct 2007). Pulsatile arterial pressure is predominantly determined by the aortic reservoir, which can be determined non-invasively from peripheral measurement sites. J HUM HYPERTENS. 21:849-850.
  • Sun N; Wood NB; Hughes AD; Thom SA; Xu XY. (Oct 2007). Influence of pulsatile flow on LDL transport in the arterial wall. Ann Biomed Eng. 35:1782-1790. DOI.
  • Augst AD; Ariff B; McG Thom SA; Xu XY; Hughes AD. (Aug 2007). Analysis of complex flow and the relationship between blood pressure, wall shear stress, and intima-media thickness in the human carotid artery. Am J Physiol Heart Circ Physiol. 293:H1031-H1037. DOI.
  • Curtis SL; Zambanini A; Mayet J; McG Thom SA; Foale R; Parker KH; Hughes AD. (Jul 2007). Reduced systolic wave generation and increased peripheral wave reflection in chronic heart failure. Am J Physiol Heart Circ Physiol. 293:H557-H562. DOI.
  • Downie SP; Firmin DN; Wood NB; Thom SA; Hughes AD; Wolfe JNH; Xu XY. (Jul 2007). Role of MRI in investigating the effects of elastic compression stockings on the deformation of the superficial and deep veins in the lower leg. J MAGN RESON IMAGING. 26:80-85. DOI.
  • Chaturvedi N; Coady E; Mayet J; Wright AR; Shore AC; Byrd S; McG Thom SA; Kooner JS; et alSchalkwijk CG; Hughes AD. (Jul 2007). Indian Asian men have less peripheral arterial disease than European men for equivalent levels of coronary disease. Atherosclerosis. 193:204-212. DOI.
  • Sun N; Wood NB; Hughes AD; Thom SA; Yun Xu X. (Jun 2007). Effects of transmural pressure and wall shear stress on LDL accumulation in the arterial wall: a numerical study using a multilayered model. Am J Physiol Heart Circ Physiol. 292:H3148-H3157. DOI.
  • Martinez-Perez ME; Hughes AD; Thom SA; Bharath AA; Parker KH. (Feb 2007). Segmentation of blood vessels from red-free and fluorescein retinal images. MED IMAGE ANAL. 11:47-61. DOI.
  • Tillin T; Chambers J; Malik I; Coady E; Byrd S; Mayet J; Wright AR; Kooner J; et alShore A; Thom S; Chaturvedi N; Hughes A. (Feb 2007). Measurement of pulse wave velocity: site matters. J Hypertens. 25:383-389. DOI.
  • Torii R; Wood NB; Hughes AD; Thom SA; Aguado-Sierra J; Davies JE; Francis DP; Parker KH; et alXu XY. (2007). A computational study on the influence of catheter-delivered intravascular probes on blood flow in a coronary artery model. J Biomech. 40:2501-2509. DOI.
  • Hughes AD; Coady E; Raynor S; Mayet J; Wright AR; Shore AC; Kooner JS; Thom SA; et alChaturvedi N. (Jan 2007). Reduced endothelial progenitor cells in European and South Asian men with atherosclerosis. Eur J Clin Invest. 37:35-41. DOI.
  • Wood NB; Zhao SZ; Zambanini A; Jackson M; Gedroyc W; Thom SA; Hughes AD; Xu XY. (Nov 2006). Curvature and tortuosity of the superficial femoral artery: a possible risk factor for peripheral arterial disease. J Appl Physiol. 101:1412-1418. DOI.
  • Williams B; Lacy PS; Thurston H; Thom S; Hughes A; Cruickshank K; Stanton A; Collier D; et alO'Rourke M. (10 Oct 2006). Response to letters regarding article, "differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: Principal results of the Conduit Artery Function Evaluation (CAFE) Study". CIRCULATION. 114:E540-E541. DOI.
  • Ariff B; Zambanini A; Vamadeva S; Barratt D; Xu Y; Sever P; Stanton A; Hughes A; et alThom S. (Sep 2006). Candesartan- and atenolol-based treatments induce different patterns of carotid artery and left ventricular remodeling in hypertension. Stroke. 37:2381-2384. DOI.
  • Sun N; Wood NB; Hughes AD; Thom SA; Xu XY. (Jul 2006). Fluid-wall modelling of mass transfer in an axisymmetric stenosis: effects of shear-dependent transport properties. Ann Biomed Eng. 34:1119-1128. DOI.
  • Witt N; Wong TY; Hughes AD; Chaturvedi N; Klein BE; Evans R; McNamara M; Thom SA; et alKlein R. (May 2006). Abnormalities of retinal microvascular structure and risk of mortality from ischemic heart disease and stroke. Hypertension. 47:975-981. DOI.
  • Hughes AD; Martinez-Perez E; Jabbar AS; Hassan A; Witt NW; Mistry PD; Chapman N; Stanton AV; et alBeevers G; Pedrinelli R; Parker KH; Thom SA. (May 2006). Quantification of topological changes in retinal vascular architecture in essential and malignant hypertension. J Hypertens. 24:889-894. DOI.
  • Williams B; Lacy PS; Thom SM; Cruickshank K; Stanton A; Collier D; Hughes AD; Thurston H; et alO'Rourke M; CAFE Investigators; Anglo-Scandinavian Cardiac Outcomes Trial Investigators; CAFE Steering Committee and Writing Committee. (7 Mar 2006). Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study. Circulation. 113:1213-1225. DOI.
  • Leung JH; Wright AR; Cheshire N; Crane J; Thom SA; Hughes AD; Xu Y. (19 May 2006). Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models. BIOMED ENG ONLINE. 5. DOI.
  • Zambanini A; Cunningham SL; Parker KH; Khir AW; McG Thom SA; Hughes AD. (Jul 2005). Wave-energy patterns in carotid, brachial, and radial arteries: a noninvasive approach using wave-intensity analysis. Am J Physiol Heart Circ Physiol. 289:H270-H276. DOI.
  • Crowe LA; Ariff B; Keegan J; Mohiaddin RH; Yang GZ; Hughes AD; McG Thom SA; Firmin DN. (Mar 2005). Comparison between three-dimensional volume-selective turbo spin-echo imaging and two-dimensional ultrasound for assessing carotid artery structure and function. J Magn Reson Imaging. 21:282-289. DOI.
  • Wimalasundera RC; Thom SA; Regan L; Hughes AD. (Feb 2005). Effects of vasoactive agents on intracellular calcium and force in myometrial and subcutaneous resistance arteries isolated from preeclamptic, pregnant, and nonpregnant woman. Am J Obstet Gynecol. 192:625-632. DOI.
  • Glor FP; Ariff B; Hughes AD; Crowe LA; Verdonck PR; Barratt DC; McG Thom SA; Firmin DN; et alXu XY. (Dec 2004). Image-based carotid flow reconstruction: a comparison between MRI and ultrasound. Physiol Meas. 25:1495-1509.
  • Barratt DC; Ariff BB; Humphries KN; Thom SA; Hughes AD. (May 2004). Reconstruction and quantification of the carotid artery bifurcation from 3-D ultrasound images. IEEE Trans Med Imaging. 23:567-583.
  • Williams B; Poulter NR; Brown MJ; Davis M; McInnes GT; Potter JF; Sever PS; Thom SM; et alBHS guidelines working party, for the British Hypertension Society. (13 Mar 2004). British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary. BMJ. 328:634-640. DOI.
  • Williams B; Poulter NR; Brown MJ; Davis M; McInnes GT; Potter JF; Sever PS; Thom SM. (Mar 2004). Guidelines for management of hypertension: Report of the fourth working party of the British Hypertension Society, 2004 - BHSIV. J HUM HYPERTENS. 18:139-185. DOI.
  • Leung J; Wright A; Cheshire N; Thom SA; Hughes AD; Xu XY. (2004). Flow patterns and wall shear stresses in patient-specific models of the abdominal aortic aneurysm. Stud Health Technol Inform. 103:235-242.
  • Glor FP; Ariff B; Crowe LA; Hughes AD; Cheong PL; Thom SA; Verdonck PR; Firmin DN; et alBarratt DC; Xu XY. (Dec 2003). Carotid geometry reconstruction: a comparison between MRI and ultrasound. Med Phys. 30:3251-3261.
  • Bicknell CD; Cowling MG; Clark MW; Delis KT; Jenkins MP; Hughes AD; Thom SA; Wolfe JH; et alCheshire NJ. (Jul 2003). Carotid angioplasty in a pulsatile flow model: factors affecting embolic potential. Eur J Vasc Endovasc Surg. 26:22-31.
  • Long Q; Ariff B; Zhao SZ; Thom SA; Hughes AD; Xu XY. (Apr 2003). Reproducibility study of 3D geometrical reconstruction of the human carotid bifurcation from magnetic resonance images. Magn Reson Med. 49:665-674. DOI.
  • Augst AD; Barratt DC; Hughes AD; Glor FP; McG Thom SA; Xu XY. (Apr 2003). Accuracy and reproducibility of CFD predicted wall shear stress using 3D ultrasound images. J Biomech Eng. 125:218-222.
  • Brown MJ; Cruickshank JK; Dominiczak AF; MacGregor GA; Poulter NR; Russell GI; Thom S; Williams B. (Feb 2003). Better blood pressure control: how to combine drugs. J HUM HYPERTENS. 17:81-86. DOI.
  • Glor FP; Long Q; Hughes AD; Augst AD; Ariff B; Thom SA; Verdonck PR; Xu XY. (Feb 2003). Reproducibility study of magnetic resonance image-based computational fluid dynamics prediction of carotid bifurcation flow. Ann Biomed Eng. 31:142-151.
  • Augst AD; Barratt DC; Hughes AD; Thom SA; Xu XY. (2003). Various issues relating to computational fluid dynamics simulations of carotid bifurcation flow based on models reconstructed from three-dimensional ultrasound images. Proc Inst Mech Eng H. 217:393-403.
  • Mayet J; Ariff B; Wasan B; Chapman N; Shahi M; Senior R; Foale RA; Thom SA. (Dec 2002). Midwall myocardial shortening in athletic left ventricular hypertrophy. Int J Cardiol. 86:233-238.
  • Langham J; Tucker H; Sloan D; Pettifer J; Thom S; Hemingway H. (Oct 2002). Secondary prevention of cardiovascular disease: a randomised trial of training in information management, evidence-based medicine, both or neither: the PIER trial. Br J Gen Pract. 52:818-824.
  • Zhao SZ; Ariff B; Long Q; Hughes AD; Thom SA; Stanton AV; Xu XY. (Oct 2002). Inter-individual variations in wall shear stress and mechanical stress distributions at the carotid artery bifurcation of healthy humans. J Biomech. 35:1367-1377.
  • Martinez-Perez ME; Hughes AD; Stanton AV; Thom SA; Chapman N; Bharath AA; Parker KH. (Aug 2002). Retinal vascular tree morphology: a semi-automatic quantification. IEEE Trans Biomed Eng. 49:912-917. DOI.
  • Chapman N; Dell'omo G; Sartini MS; Witt N; Hughes A; Thom S; Pedrinelli R. (Aug 2002). Peripheral vascular disease is associated with abnormal arteriolar diameter relationships at bifurcations in the human retina. Clin Sci (Lond). 103:111-116.
  • Ariff B; Stanton A; Barratt D; Augst A; Glor F; Poulter N; Sever P; Xu Y; et alHughes A; Thom SA. (Jun 2002). Comparison of the effects of antihypertensive treatment with angiotensin II blockade and beta-blockade on carotid wall structure and haemodynamics: protocol and baseline demographics. J Renin Angiotensin Aldosterone Syst. 3:116-122. DOI.
  • Wimalasundera RC; McG Thom SA; Regan L; Hughes AD. (Jun 2002). Action of the endothelin receptor (ETA) antagonist BQ-123 on forearm blood flow in young normotensive subjects. Clin Sci (Lond). 102:661-666.
  • Mayet J; Stanton AV; Chapman N; Foale RA; Hughes AD; Thom SA. (Apr 2002). Is carotid artery intima-media thickening a reliable marker of early atherosclerosis?. J Cardiovasc Risk. 9:77-81.
  • Wasan BS; Patel N; Stanbridge R; Glenville B; Thom S; Foale RA; Mayet J. (6 Mar 2002). Does off pump coronary artery bypass graft surgery reduce post-operative right ventricular dysfunction?. J AM COLL CARDIOL. 39:320A-320A.
  • Starmans-Kool MJ; Stanton AV; Zhao S; Xu XY; Thom SA; Hughes AD. (Mar 2002). Measurement of hemodynamics in human carotid artery using ultrasound and computational fluid dynamics. J Appl Physiol. 92:957-961. DOI.
  • Stanton AV; Mayet J; Chapman N; Foale RA; Hughes AD; Thom SA. (Mar 2002). Ethnic differences in carotid and left ventricular hypertrophy. J Hypertens. 20:539-543.
  • Zambanini A; Khir AW; Byrd SM; Parker KH; Thom SAM; Hughes AD. (2002). Wave intensity analysis: a novel non-invasive method for determining arterial wave transmission. Comp Cardiol. 29:717-720.
  • King E; Xu XY; Hughes AD; Long Q; Thom SA; Parker KH. (2002). Quantification of the non-planarity of the human carotid bifurcation. Biorheology. 39:419-424.
  • Stanton AV; Chapman JN; Mayet J; Sever PS; Poulter NR; Hughes AD; Thom SA. (Nov 2001). Effects of blood pressure lowering with amlodipine or lisinopril on vascular structure of the common carotid artery. Clin Sci (Lond). 101:455-464.
  • Wasan BS; Hughes A; Thom SA; Foale RA; Mayet J. (23 Oct 2001). Regional diastolic dysfunction in coronary artery disease. CIRCULATION. 104:636-636.
  • Barratt DC; Davies AH; Hughes AD; Thom SA; Humphries KN. (Oct 2001). Accuracy of an electromagnetic three-dimensional ultrasound system for carotid artery imaging. Ultrasound Med Biol. 27:1421-1425.
  • Stanton A; Fitzgerald D; Hughes A; Mayet J; O'Brien E; Poulter NR; Sever PS; Shields D; et alThom S; Anglo-Scandinavian Cardiac Outcomes Trial. (Aug 2001). An intensive phenotyping study to enable the future examination of genetic influences on hypertension-associated cardiovascular disease. J Hum Hypertens. 15 Suppl 1:S13-S18.
  • O'Brien E; McInnes GT; Stanton A; Thom S; Caulfield M; Atkins N; Nichol FM; Anglo-Scandinavian Cardiac Outcomes Trial. (Aug 2001). Ambulatory blood pressure monitoring and 24-h blood pressure control as predictors of outcome in treated hypertensive patients. J Hum Hypertens. 15 Suppl 1:S47-S51.
  • Thom S; Whitehouse A; Sever P; Poulter N; Anglo-Scandinavian Cardiac Outcomes Trial. (Aug 2001). Non-specific effects of inclusion in a clinical trial: information from ASCOT. J Hum Hypertens. 15 Suppl 1:S81-S82.
  • Francis D; Lane R; Mayet J; Foale RA; Thom S; Peters NS; Anglo-Scandinavian Cardiac Outcomes Trial. (Aug 2001). Microvolt T wave alternans in patients with hypertension and left ventricular hypertrophy. J Hum Hypertens. 15 Suppl 1:S95-S96.
  • Hughes AD; Thom S. (Jul 2001). Wearing your heart in your sleeve?. Eur Heart J. 22:1071-1073. DOI.
  • Barratt DC; Davies AH; Hughes AD; Thom SA; Humphries KN. (Jul 2001). Optimisation and evaluation of an electromagnetic tracking device for high-accuracy three-dimensional ultrasound imaging of the carotid arteries. Ultrasound Med Biol. 27:957-968.
  • Chapman N; Mayet J; Ozkor M; Lampe FC; Thom SA; Poulter NR. (May 2001). QT intervals and QT dispersion as measures of left ventricular hypertrophy in an unselected hypertensive population. Am J Hypertens. 14:455-462.
  • Chapman N; Witt N; Gao X; Bharath AA; Stanton AV; Thom SA; Hughes AD. (Jan 2001). Computer algorithms for the automated measurement of retinal arteriolar diameters. Br J Ophthalmol. 85:74-79.
  • Chapman N; Haimes G; Stanton AV; Thom SA; Hughes AD. (Dec 2000). Acute effects of oxygen and carbon dioxide on retinal vascular network geometry in hypertensive and normotensive subjects. Clin Sci (Lond). 99:483-488.
  • Mayet J; Ariff B; Wasan B; Chapman N; Shahi M; Poulter NR; Sever PS; Foale RA; et alThom SA. (Nov 2000). Improvement in midwall myocardial shortening with regression of left ventricular hypertrophy. Hypertension. 36:755-759.
  • Ariff BB; Zambanini A; Mayet J; Hughes AD; Thom SM. (31 Oct 2000). Intima-medial area: A more robust method than intima media thickness for analysing non-cardiac gated common carotid images. CIRCULATION. 102:729-729.
  • Gao XW; Bharath A; Stanton A; Hughes A; Chapman N; Thom S. (Oct 2000). Quantification and characterisation of arteries in retinal images. Comput Methods Programs Biomed. 63:133-146.
  • Zhao SZ; Zambanini A; Long Q; Xu XY; Hughes AD; Thom SA. (Oct 2000). Difference in anatomical features of the femoral artery between male and female. HYPERTENSION. 36:666-666.
  • Zhao SZ; Xu XY; Hughes AD; Thom SA; Stanton AV; Ariff B; Long Q. (Aug 2000). Blood flow and vessel mechanics in a physiologically realistic model of a human carotid arterial bifurcation. J Biomech. 33:975-984.
  • Chapman JN; Haimes G; Stanton AV; Thom SA; Hughes AD. (Jun 2000). Acute effects of oxygen and carbon dioxide on retinal arteriolar network geometry: differences between hypertensives and normotensives. J PHYSIOL-LONDON. 525:20P-21P.
  • Xu XY; Zhao SZ; Long Q; Ariff B; Hughes AD; Thom SA. (Jun 2000). 3D reconstruction of flow patterns and shear stress in human arteries. J PHYSIOL-LONDON. 525:4P-4P.
  • Chapman N; Mayet J; Ozkor M; Foale R; Thom S; Poulter N. (Jun 2000). Ethnic and gender differences in electrocardiographic QT length and QT dispersion in hypertensive subjects. J Hum Hypertens. 14:403-405.
  • Ariff B; Thom SA; Foale RA; Mayet J. (Jun 2000). Stress echocardiography for the diagnosis of ischaemia in hypertensives. J Hum Hypertens. 14:399-401.
  • Long Q; Xu XY; Ariff B; Thom SA; Hughes AD; Stanton AV. (Mar 2000). Reconstruction of blood flow patterns in a human carotid bifurcation: a combined CFD and MRI study. J Magn Reson Imaging. 11:299-311.
  • Chapman JN; Mayet J; Foale RA; Thom SA. (Dec 1999). Intraventricular dispersion of E wave velocity: an alternative measure of left ventricular diastolic function in hypertensive patients?. J Hum Hypertens. 13:867-869.
  • Coombes JE; Hughes AD; Thom SA. (Dec 1999). Intravascular pressure-evoked changes in intracellular calcium [Ca2+]i and tone in rat mesenteric and rabbit cerebral arteries in vitro. J Hum Hypertens. 13:855-858.
  • Starmans-Kool M; Stanton A; Zhao S; Xu Y; Hughes A; Thom S; Struijker H. (Oct 1999). Carotid haemodynamics and the effects of salt. HYPERTENSION. 34:706-706.
  • Wimalasundera R; Regan L; Thom S; Hughes A. (Oct 1999). Effects of TNF-alpha on relaxation of rat mesenteric vessels: a role in pre-eclampsia?. HYPERTENSION. 34:701-701.
  • Chapman JN; Mayet J; Chang CL; Foale RA; Thom SA; Poulter NR. (May 1999). Ethnic differences in the identification of left ventricular hypertrophy in the hypertensive patient. Am J Hypertens. 12:437-442.
  • Zhao SZ; Xu XY; Collins MW; Stanton AV; Hughes AD; Thom SA. (May 1999). Flow in carotid bifurcations: effect of the superior thyroid artery. Med Eng Phys. 21:207-214.
  • Mayet J; Kanagaratnam P; Shahi M; Senior R; Doherty M; Poulter NR; Sever PS; Handler CE; et alThom SA; Foale RA. (Apr 1999). QT dispersion in athletic left ventricular hypertrophy. Am Heart J. 137:678-681.
  • Stanton AV; Chapman JN; Sever PS; Poulter NR; Hughes AD; Thom SA. (Oct 1998). Greater regression of early atherosclerosis by calcium channel blockade than by angiotensin converting enzyme inhibition. HYPERTENSION. 32:795-795.
  • Thom SA; Gao X; Stanton AV; Chapman JN; Bharath A; Hughes AD. (Jun 1998). A computer system for automated retinal microvascular architecture quantification. J HYPERTENS. 16:S106-S106.
  • Stanton AV; Chapman JN; Sever PS; Poulter NR; Hughes AD; Thom SA. (Jun 1998). Greater regression of early atherosclerosis by calcium channel blockade than by angiotensin converting enzyme inhibition. J HYPERTENS. 16:S25-S25.
  • Chapman N; Mayet J; Chang L; Foale R; Thom S; Poulter N. (Jun 1998). Ethnic differences in ECG detection of left ventricular hypertrophy. J HYPERTENS. 16:S199-S199.
  • Chester AH; Borland JA; Morrison KJ; Amrani M; Thom SM; Yacoub MH. (May 1998). Reactivity of small intramyocardial arteries from atherosclerotic and non-atherosclerotic human hearts. J Vasc Res. 35:170-178.
  • Mayet J; Chapman N; Li CK; Shahi M; Poulter NR; Sever PS; Foale RA; Thom SA. (May 1998). Ethnic differences in the hypertensive heart and 24-hour blood pressure profile. Hypertension. 31:1190-1194.
  • Chapman N; Mohamudally A; Cerutti A; Stanton A; Sayer AA; Cooper C; Barker D; Rauf A; et alEvans J; Wormald R; Sever P; Hughes A; Thom S. (Dec 1997). Retinal vascular network architecture in low-birth-weight men. J Hypertens. 15:1449-1453.
  • Thom S. (Nov 1997). Arterial structural modifications in hypertension - Effects of treatment. EUROPEAN HEART JOURNAL. 18:E2-E4.
  • Mayet J; O'Kane KP; Elton R; Johnstone HA; Shahi M; Ozkor MA; Stanton AV; Poulter NR; et alSever PS; Foale RA; Webb DJ; Thom SA. (Sep 1997). Left ventricular hypertrophy, blood pressure and ACE genotype in untreated hypertension. J Hum Hypertens. 11:595-597.
  • Mayet J; Shahi M; Poulter NR; Sever PS; Foale RA; Thom SA. (Sep 1997). Left ventricular geometry in presenting untreated hypertension. J Hum Hypertens. 11:593-594.
  • Mayet J; Chapman N; Shahi M; Poulter NR; Cunningham DA; Dave S; Kooner J; Sever PS; et alFoale RA; Thom SA. (Jun 1997). The effects on cardiac arrhythmias of antihypertensive therapy causing regression of left ventricular hypertrophy. Am J Hypertens. 10:611-618.
  • Mayet J; Shahi M; McGrath K; Poulter NR; Sever PS; Foale RA; Thom SA. (Nov 1996). Left ventricular hypertrophy and QT dispersion in hypertension. Hypertension. 28:791-796.
  • Mayet J; Shahi M; McGrath K; Poulter NR; Sever PS; Foale RA; Thom SA. (Oct 1996). QT dispersion is improved by antihypertensive therapy. HYPERTENSION. 28:703-703.
  • Stanton AV; Mayet J; Hughes AD; Chapman NJ; Sever PS; Thom SA. (Oct 1996). Carotid and femoral artery intima-media thickness is similar in black and white hypertensive patients. HYPERTENSION. 28:703-703.
  • Chapman N; Mohamudally A; Stanton A; Sever P; Sayer AA; Cooper C; Barker D; Wormald R; et alEvans J; Rauf A; Hughes A; Thom S. (Oct 1996). Abnormal microvascular network geometry - The link between low birth weight and increased cardiovascular risk?. HYPERTENSION. 28:703-703.
  • Thom SA; Stanton AV; King LA; Sever PS; Hughes AD. (Oct 1996). Arteriolar length-diameter ratio; A geometric parameter of the retinal vasculature diagnostic of hypertension. HYPERTENSION. 28:703-703.
  • King LA; Stanton AV; Sever PS; Thom SA; Hughes AD. (Jun 1996). Arteriolar length-diameter (L:D) ratio: a geometric parameter of the retinal vasculature diagnostic of hypertension. J Hum Hypertens. 10:417-418.
  • Stanton AV; Wasan B; Cerutti A; Ford S; Marsh R; Sever PP; Thom SA; Hughes AD. (Dec 1995). Vascular network changes in the retina with age and hypertension. J Hypertens. 13:1724-1728.
  • Mayet J; Stanton AV; Sinclair AM; MacKay J; Shahi M; Foale RA; Nicolaides A; Poulter NR; et alSever PS; Thom SA. (Jul 1995). The effects of antihypertensive therapy on carotid vascular structure in man. Cardiovasc Res. 30:147-152.
  • Mayet J; Shahi M; Poulter NR; Sever PS; Foale RA; Thom SA. (30 Jun 1995). Left ventricular diastolic function in hypertension: a 4 year follow-up study. Int J Cardiol. 50:181-188.
  • Mayet J; Shahi M; Hughes AD; Stanton AV; Poulter NR; Sever PS; Foale RA; Thom SA. (Jun 1995). Left ventricular structure and function in previously untreated hypertensive patients: the importance of blood pressure, the nocturnal blood pressure dip and heart rate. J Cardiovasc Risk. 2:255-261.
  • Mayet J; Shahi M; Poulter NR; Sever PS; Thom SA; Foale RA. (Feb 1995). Ventricular arrhythmias in hypertension: in which patients do they occur?. J Hypertens. 13:269-276.
  • Hughes AD; Sinclair AM; Geroulakos G; Mayet J; Mackay J; Shahi M; Thom S; Nicolaides A; et alSever PS. (Jan 1995). Structural changes in the cardiovascular system of untreated essential hypertensives. Blood Press. 4:42-47.
  • Mayet J; Shahi M; Foale RA; Poulter NR; Sever PS; McG Thom SA. (16 Apr 1994). Racial differences in cardiac structure and function in essential hypertension. BMJ. 308:1011-1014.
  • Hughes AD; Sinclair AM; Geroulakos G; Mayet J; Mackay J; Shahi M; Thom S; Nicolaides A; et alSever PS. (Aug 1993). Structural changes in the heart and carotid arteries associated with hypertension in humans. J Hum Hypertens. 7:395-397.
  • McManus IC; Vincent CA; Thom S; Kidd J. (15 May 1993). Teaching communication skills to clinical students. BMJ. 306:1322-1327.
  • MCMANUS IC; VINCENT CA; THOM S; KIDD J. (15 May 1993). HOW-TO-DO-IT - TEACHING COMMUNICATION-SKILLS TO CLINICAL STUDENTS. BRIT MED J. 306:1322-1327.
  • Parkinson NA; Thom SM; Hughes AD; Sever PS; Mulvany MJ; Nielsen H. (Jul 1992). Neurally evoked responses of human isolated resistance arteries are mediated by both alpha 1- and alpha 2-adrenoceptors. Br J Pharmacol. 106:568-573.
  • THOM S; HUGHES A; SCHACHTER M; SEVER P. (25 Jan 1992). CELIPROLOL. LANCET. 339:247-247.
  • Garcha R; Schachter M; Hughes A; Thom SM; Sever P. (Dec 1991). Amlodipine inhibition of alpha-agonist induced contraction in human resistance vessels. J Hypertens Suppl. 9:S368-S369.
  • Shahi M; Thom S; Poulter N; Sever PS; Foale RA. (Sep 1991). The effects of blood pressure reduction on abnormal left ventricular diastolic function in hypertensive patients. Eur Heart J. 12:974-979.
  • Martin GN; Thom SA; Sever PS. (Mar 1991). The effects of adenosine triphosphate (ATP) and related purines on human isolated subcutaneous and omental resistance arteries. Br J Pharmacol. 102:645-650.
  • Shahi M; Thom S; Poulter N; Sever PS; Foale RA. (Feb 1991). Determinants of left ventricular filling in hypertension. J Hum Hypertens. 5:27-34.
  • Shahi M; Thom S; Poulter N; Sever PS; Foale RA. (25 Aug 1990). Regression of hypertensive left ventricular hypertrophy and left ventricular diastolic function. Lancet. 336:458-461.
  • Thom S; Bunker J; Callister W; Poulter N; Sever P; Zographos D. (Dec 1989). Multiple risk factor evaluation in a hypertension clinic. J Hypertens Suppl. 7:S330-S331.
  • Nielsen H; Thom SM; Hughes AD; Martin GN; Mulvany MJ; Sever PS. (Jul 1989). Postjunctional alpha 2-adrenoceptors mediate vasoconstriction in human subcutaneous resistance vessels. Br J Pharmacol. 97:829-834.
  • Hughes AD; Thom SA; Woodall N; Schachter M; Hair WM; Martin GN; Sever PS. (1989). Human vascular responses to endothelin-1: observations in vivo and in vitro. J Cardiovasc Pharmacol. 13 Suppl 5:S225-S228.
  • Hughes AD; Thom SA; Martin GN; Nielsen H; Hair WM; Schachter M; Sever PS. (Dec 1988). Size and site-dependent heterogeneity of human vascular responses in vitro. J Hypertens Suppl. 6:S173-S175.
  • Hughes A; Thom S; Goldberg P; Martin G; Sever P. (Feb 1988). Direct effect of alpha-human atrial natriuretic peptide on human vasculature in vivo and in vitro. Clin Sci (Lond). 74:207-211.
  • Thom S; Hughes A; Martin G; Sever PS. (Nov 1987). Endothelium-dependent relaxation in isolated human arteries and veins. Clin Sci (Lond). 73:547-552.
  • Hughes A; Martin G; Goldberg P; Thom S; Sever P. (Nov 1987). No evidence for a direct vasodilatory effect of celiprolol on human vasculature in vivo or in vitro. J Cardiovasc Pharmacol. 10:589-592.
  • Thom SA; Hughes AD; Martin GN; Sever PS. (Dec 1985). The release of the endothelium derived relaxing factor from isolated human arteries. J Hypertens Suppl. 3:S97-S99.
  • Redman D; Thom SA; Hughes AD; Hasan S; Sever PS. (Dec 1985). Human vasodilator responses to a dopamine agonist: possible mechanisms. J Hypertens Suppl. 3:S177-S178.
  • Torii R; Keegan J; Wood NB; Dowsey AW; Hughes AD; Yang G; Firmin DN; Thom SA; et alXu Y. (2010). MR image-based geometric and hemodynamic investigation of the right coronary artery with dynamic vessel motion. Annals of Biomedical Engineering. in press.

Books

  • Poulter N; Thom S; Kirby M. Shared care for hypertension. (2001).

Conferences

  • Davies JE; Lacy PS; Cruickshank K; Stanton A; Collier D; Thurston H; Williams B; Parker KH; et alThom SM; Hughes AD. Excess pressure is higher in atenolol-treated individuals and independently predicts cardiovascular events in the CAFE substudy of ASCOT. 31:902-902. (Sep 2010).
  • Sever PS; Poulter NR; Chang CL; Thom SA; Hughes AD; Welsh P; Sattar N. The Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT): Testing C-Reactive Protein at Baseline and on-Treatment as an Independent Predictor of Cardiovascular Outcomes. 122:2219-2219. (23 Nov 2010).
  • Dolan E; Caulfield M; Thom S; McInnes G; Collier D; O'Brien E; Stanton A. AMBULATORY ARTERIAL STIFFNESS INDEX PREDICTS CARDIOVASCULAR MORBIDITY AND MORTALITY IN TREATED HYPERTENSIVE PATIENTS - AN ANGLO - SCANDINAVIAN CARDIAC OUTCOME TRIAL SUB-STUDY. 28:E13-E14. (Jun 2010).
  • Davies J; Tillin T; Malaweera A; Lacy P; Cruickshank K; Stanton A; Collier D; Thurston H; et alWilliams B; Parker K; Thom S; Hughes A. EXCESS PRESSURE IS HIGHER IN ATENOLOL-TREATED INDIVIDUALS AND INDEPENDENTLY PREDICTS CARDIOVASCULAR EVENTS IN THE CAFE SUBSTUDY OF ASCOT. 28:E247-E247. (Jun 2010).
  • Tan FPP; Borghi A; Mohiaddin RH; Wood NB; Thom S; Xu XY. Analysis of flow patterns in a patient-specific thoracic aortic aneurysm model. 87:680-690. (2009). DOI.
  • Liu D; Wood NB; Xu XY; Witt N; Hughes AD; Thom SAMcG. 3D Reconstruction of the Retinal Arterial Tree Using Subject-Specific Fundus Images. 13:187-201. (2009).
  • Bathula R; Hughes AD; Thom S; Panerai R; Potter J; Francis D; Shore A; Kooner J; et alChaturvedi N. Ethnic differences in sympathovagal balance and baroreceptor function are explained by dysglycaemia. 52:758-758. (Oct 2008).
  • Stettler C; Witt N; Tapp R; Stanton A; Thom S; Allemann S; Tillin T; Hughes AD; et alChaturvedi N. Retinal microvascular changes and risk of coronary heart disease in hypertensive diabetic and non-diabetic individuals: an ASCOT substudy. 44th Annual Meeting of the European-Association-for-the-Study-of-Diabetes. 51:S16-S16. (Sep 2008).
  • Torii R; Wood NB; Hadjiloizou N; Dowsey AW; Wright AR; Hughes AD; Davies J; Francis D; et alMayet J; Yang GZ; Thom SA; Xu XY. Differences in coronary artery haemodynamics due to changes in flow and vascular geometry after percutaneous coronary intervention. Annual Scientific Conference of the British-Cardiovascular-Society. 94:A1-A2. (Jul 2008).
  • Mansity C; Zambanini A; Poulter N; Sever P; Parker K; Thom S; Hughes A. Atorvastatin lowers augmentation index and wave reflection in hypertensive subjects: An ASCOT-LLA substudy. 18th Scientific Meeting of the European-Society-of-Hypertension/22nd Scientific Meeting of the International-Society-of-Hypertension. 26:S458-S458. (Jun 2008).
  • Tan FPP; Soloperto G; Wood NB; Thom S; Hughes A; Xu XY. Advanced Computational Models for Disturbed and Turbulent Flow in Stenosed Human Carotid Artery Bifurcation. 21:390-394. (2008).
  • Tapp R; Sharp A; Stanton A; O'Brien E; Chaturvedi N; Sever P; Poulter N; Hughes A; et alThom S; Mayet J. Left ventricular diastolic function assessed by tissue Doppler echocardiography is impaired by beta-blocker plus diuretic-based therapy compared with calcium, antagonist plus Ace inhibitor-based therapy: An ASCOT substudy. 116:609-609. (16 Oct 2007).
  • Hughes A; Manisty C; Zambanini A; Mayet J; Poulter N; Sever P; Parker K; Thom S. Lower augmentation index and wave reflection in hypertensive subjects treated with atorvastatin; An ASCOT-LLA substudy. 116:609-609. (16 Oct 2007).
  • Alakakone A; Tillin T; Chambers J; Malik I; Coady E; Raynor S; Mayet J; Wright A; et alKooner J; Shore A; Thom S; Chaturvedi N; Hughes A. Do differences in lower limb blood flow explain the ethnic disparity in peripheral arterial disease incidence between South Asians and Europeans?. 12th Annual Meeting of the European-Council-for-Cardiovascular-Research. 50:803-803. (Oct 2007).
  • Joshi M; Tillin T; Malik I; Coady E; Raynor S; Mayet J; Wright A; Kooner J; et alShore A; Thom S; Chaturvedi N; Hughes A. Associations between lower limb arterial calcification and markers of coronary and peripheral arterial disease in South Asian and European men. 50:819-820. (Oct 2007).
  • Manisty C; Davies J; Whinnett Z; Francis D; Zambanini A; Zambanini A; Curtis S; Thom S; et alHughes A; Mayet J. Differences in the magnitude rather than the timing of wave reflection can explain the ASCOT results. 93:A80-A80. (Jun 2007).
  • Lacy P; Cruickshank K; Thom S; Stanton A; Collier D; Williams B. Diabetes accentuates the differential impact of blood pressure lowering drugs on central aortic pressure: Principal results from cafe-diabetes; The diabetic cohort within the conduit artery functional evaluation (CAFE) study. 17th European Meeting on Hypertension. 25:S279-S280. (Jun 2007).
  • Williams B; Lacy PS; Cruickshank KJ; Thom S; Stanton A; Collier D. Effect of statin therapy on central aortic pressures and hemodynamics: Principal results of the lipid lowering arm of the conduit artery function evaluation study (CAFE-LLA). 49:404A-404A. (6 Mar 2007).
  • Manisty CH; Davies JE; Zambanini A; Curtis SL; Whinnett ZI; Thom SM; Francis DP; Hughes A; et alMayet J. Differential arterial wave reflection in ASCOT: An explanation for the results?. 79th Annual Scientific Session of the American-Heart-Association. 114:537-537. (31 Oct 2006).
  • Dowsey AW; Keegan J; Lerotic M; Thom S; Firmin D; Yang GZ. Motion-compensated MR valve imaging with COMB tag tracking and super-resolution enhancement. 9th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2006). 11:478-491. Lecture Notes in Computer Science (Oct 2006).
  • Chaturvedi N; Coady E; Mayet J; Wright AR; Shore AC; Thom SAMCG; Kooner J; Hughes AD. Femoral atherosclerosis is reduced in South Asian compared with European men. 7:104-104. (Jun 2006).
  • Sharp A; Thom S; Francis D; Hughes A; Stanton A; Zambanini A; O'Brien E; Lyons S; et alByrd S; Poulter N; Sever P; Mayet J. Ethnicity and left ventricular diastolic function in hypertension: An ASCOT substudy. Annual Scientific Conference of the British-Society-Promoting-Cardiovascular-Health. 92:A34-A34. (May 2006).
  • Sharp A; Mayet J; Francis D; Hughes A; Stanton A; Kyd P; Zambanini A; Poulter N; et alSever P; Thom S. The effect of ethnicity on BNP levels in hyplkiension - An ASCOT sub-study. 92:A49-A49. (May 2006).
  • Manisty C; Davies J; Francis D; Zambanini A; Thom S; Hughes A; Mayet J. The protodiastolic expansion wave: A compensatory mechanism for the reduction in longitudinal relaxation velocity with ageing?. 92:A61-A62. (May 2006).
  • Sharp A; Thom S; Francis D; Hughes A; Stanton A; Zombanini A; O'Brien E; Lyons S; et alLang C; Byrd S; Poulter N; Sever P; Mayet J. The ability of tissue Doppler echocardiography to predict future cardiovascular events in a hypertensive population: An ASCOT substudy. 92:A34-A35. (May 2006).
  • Manisty C; Davies J; Whinnett Z; Francis D; Zambanini A; Cunningham S; Thom S; Hughes A; et alMayet J. The role of wave reflection in the pathophysiology of hypertension: Assessed using non-invasive wave intensity analysis. Annual Scientific Conference of the British-Society-Promoting-Cardiovascular-Health. 92:A33-A33. (May 2006).
  • Dowsey AW; Keegan J; Lerotic M; Thom S; Firmin D; Yang GZ. Motion-compensated MR valve imaging with COMB tag tracking and super-resolution enhancement. 9:364-371. (2006).
  • Tapp R; Sharp A; Chaturvedi N; Stanton A; Mayet J; Hughes A; Thom S. Effects of blood pressure lowering with beta blocker plus diuretic-based therapy and calcium antagonist plus angiotensin converting enzyme inhibitor-based therapy on left ventricular diastolic function. 78th Annual Scientific Session of the American-Heart-Association. 112:U399-U400. (25 Oct 2005).
  • Hughes AD; Coady E; Byrd S; Mayet J; Wright A; Shore A; Kooner J; Thom SA. Circulating endothelial progenitor cells and atherosclerosis in European and South Asian subjects. 10th Annual Meeting of the European-Council-for-Cardiovascular-Research. 46:900-900. (Oct 2005).
  • Davies J; Whinnett Z; Francis D; Willson K; Foale R; Malik I; Thom S; Hughes A; et alParker K; Mayet J. Effect of nitrate administration on wave speed propagation in the human coronary artery. Annual Conference of G-MEX/MICC. 91:A66-A67. (May 2005).
  • Sharp A; Thom S; Hughes A; Francis D; Stanton A; O'Brien E; Fitzgerald D; Shields D; et alPoulter N; Sever P; Mayet J. Black hypertensives have significantly lower B-Natriuretic peptide levels than South Asians or Whites. 45:381A-381A. (1 Feb 2005).
  • Ho E; Rooney C; Harhen B; Sever P; Poulter N; Hughes A; Thom S; O'Brien E; et alFitzgerald D; Stanton A. Atherosclerosis and oxidative stress contribute to aspirin nonresponse in hypertensive subjects. 110:608-608. (26 Oct 2004).
  • Starmans-Kool M; Stanton A; Thom S; Hughes A. The effect of salt intake on arterio-ventricular function and wave reflection in the carotid artery. 14th European Meeting on Hypertension. 22:S299-S299. (Jun 2004).
  • Hughes A; Ariff B; Stanton A; Xu Y; Sever P; Thom S. Differential efects of antihypertensive drugs on vascular structure. 22:S201-S201. (Jun 2004).
  • Dotsenko O; Barratt D; Ariff B; Thom S; Hughes A. Vascular geometry reconstruction with 3D ultrasound, applied to anthropomorphic phantoms models. 22:S13-S13. (Jun 2004).
  • Ariff B; Zambanini A; Sarita V; Barratt D; Xu Y; Sever P; Chaturvedi N; Stanton A; et alThom S; Hughes A. Hemodynamic determinants of carotid artery structure in essential hypertension. 17:131A-132A. (May 2004).
  • Ho E; Rooney C; Harhen B; Sever P; Hughes A; Thom S; Fitzgerald D; Stanton A. Doubling of isoprostane formation in a large cohort of hypertensive patients despite optimal medical management. 22:S43-S43. (Feb 2004).
  • Ariff B; Zambanini A; Vamadeva S; O'Neill A; Stanton A; Xu Y; Hughes A; Thom S. Differing effects of candesartan cilexetil and atenolol on carotid artery remodelling and carotid flow in hypertension. 108:452-452. (28 Oct 2003).
  • Bicknell CD; Alkhamesi NA; Delis KD; Cowling MG; Clark MW; Thom SA; Hughes AH; Jenkins MP; et alWolfe JHN; Darzi AW; Cheshire NJW. Pre-operative biological and duplex features of carotid plaques predict embolisation during carotid endoluminal intervention. 90:120-120. (Jun 2003).
  • Ariff B; O'Neill A; Stanton A; Zambanini A; Vamadeva S; Poulter N; Sever P; Xu Y; et alHughes A; Thom S. Candesartan cilexetil & atenolol have different effects on common carotid artery remodelling in hypertension. 21:S153-S154. (Jun 2003).
  • Bicknell CD; Clark MW; Cowling MG; Alkemasi NA; Thom SA; Hughes AH; Jenkins MP; Wolfe JHN; et alDarzi AW; Cheshire NJW. Statin use and plasma matrix metalloproteinase-2 and 9 levels predict embolic potential during carotid angioplasty: an ex-vivo model. 3rd Meeting of the Society-of-Academic-and-Research-Surgery. 90:632-632. (May 2003).
  • Ariff B; O'Neill A; Xu Y; Stanton A; Sever P; Hughes A; Thom S. Divergent effects on cardiac and vascular structure in hypertensive subjects treated with candesartan and atenolol. 106:575-575. (5 Nov 2002).
  • Wasan BS; Patel N; Lane R; Thom S; Foale R; Mayet J. Does resting regional myocardial function improve after percutaneous revascularisation?. American-Heart-Association Abstracts From Scientific Sessions. 106:557-557. (5 Nov 2002).
  • Wasan BS; Lane R; Zambanini A; Thom S; Foale R; Mayet J. How does age affect regional systolic and diastolic myocardial velocities in normal subjects?. 106:709-709. (5 Nov 2002).
  • Ariff B; O'Neill A; Xu XY; Sever PS; Stanton AV; Hughes AD; Thom SM. Divergent effects on cardiac and carotid vascular remodelling in hypertensive subjects treated with candesartan cilexitil & atenolol. 40:582-582. (Oct 2002).
  • Augst AD; Barratt DC; Hughes AD; Thom SA; Xu XY. CFD modeling of carotid bifurcation blood flow using 3D ultrasound. 7th Annual Meeting of the European-Council-for-Blood-Pressure-and-Cardiovascular-Research. 40:571-571. (Oct 2002).
  • Wasan BS; Patel N; Lane R; Thom SA; Foale RA; Mayet J. Myocardial regions supplied by stenosed coronary arteries nave impaired resting diastolic function. 23:34-34. (Aug 2002).
  • Stanton A; Ghiuzeli C; Chapman N; Hughes A; Thom S. Human retinal arteriolar dilatation occurs with blood pressure lowering with amlodipine but not with lisinopril. 20:S73-S73. (Jun 2002).
  • Gao XH; Bharath A; Stanton A; Hughes A; Chapman N; Thom S. A method of vessel tracking for vessel diameter measurement on retinal images. 881-884. (2001).
  • Martinez-Perez ME; Hughes AD; Stanton AV; Thom SA; Chapman N; Bharath AA; Parker KH. Geometrical and morphological analysis of vascular branches from fundus retinal images. 3rd International Conference on Medical Image Computing and Computer-Assisted Intervention. 1935:756-765. (2000).
  • Zhao SZ; Xu XY; Collins MW; Stanton AV; Hughes AD; Thom SA. The convergence technique in numerical solutions of coupled fluid-wall problems. 70:125-134. (1999).
  • Martinez-Perez ME; Hughes AD; Stanton AV; Thom SA; Bharath AA; Parker KH. Retinal blood vessel segmentation by means of scale-space analysis and region growing. 1679:90-97. (1999).
  • Thom S. Regression of hypertensive structural changes in large arteries. Satellite Symposium on the Rationale of Combination Therapy in Hypertension, at the 18th Congress of the European-Society-of-Cardiology. 59-61. (Jun 1997).
  • Gao XH; Bharath AA; Hughes A; Stanton A; Chapman N; Thom S. Towards retinal vessel parameterisation. Medical Imaging 1997 Symposium - Image Processing. 3034:734-744. (1997).
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