Professor H Terence Cook

Publications


Journals

  • Vernon KA; Goicoechea de Jorge E; Hall AE; Fremeaux-Bacchi V; Aitman TJ; Cook HT; Hangartner R; Koziell A; et alPickering MC. (12 Apr 2012). Acute Presentation and Persistent Glomerulonephritis Following Streptococcal Infection in a Patient With Heterozygous Complement Factor H-Related Protein 5 Deficiency. Am J Kidney Dis. DOI.
  • Vernon KA; Cook HT. (Mar 2012). Complement in glomerular disease. Adv Chronic Kidney Dis. 19:84-92. DOI.
  • Le Roux S; Pepper RJ; Dufay A; Neel M; Meffray E; Lamande N; Rimbert M; Josien R; et alHamidou M; Hourmant M; Cook HT; Charreau B; Larger E; Salama AD; Fakhouri F. (1 Jan 2012). Elevated Soluble Flt1 Inhibits Endothelial Repair in PR3-ANCA-Associated Vasculitis. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 23:155-164. DOI.
  • Cook HT; Tarzi R; D'Souza Z; Laurent G; Lin W-C; Aitman TJ; Mechta-Grigoriou F; Behmoaras J. (1 Jul 2011). AP-1 Transcription Factor JunD Confers Protection from Accelerated Nephrotoxic Nephritis and Control Podocyte-Specific Vegfa Expression. AMERICAN JOURNAL OF PATHOLOGY. 179:134-140. DOI.
  • Sharp PE; Martin-Ramirez J; Boross P; Mangsbo SM; Reynolds J; Moss J; Pusey CD; Cook HT; et alTarzi RM; Verbeek JS. (Feb 2012). Increased incidence of anti-GBM disease in Fcgamma receptor 2b deficient mice, but not mice with conditional deletion of Fcgr2b on either B cells or myeloid cells alone. Mol Immunol. 50:49-56. DOI.
  • Page TH; D'Souza Z; Nakanishi S; Serikawa T; Pusey CD; Aitman TJ; Cook HT; Behmoaras J. (17 Feb 2012). Role of novel rat-specific Fc receptor in macrophage activation associated with crescentic glomerulonephritis. J Biol Chem. 287:5710-5719. DOI.
  • Reynolds J; Sando GS; Marsh OB; Salama AD; Evans DJ; Cook HT; Pusey CD. (Apr 2012). Stimulation of the PD-1/PDL-1 T-cell co-inhibitory pathway is effective in treatment of experimental autoimmune glomerulonephritis. Nephrol Dial Transplant. 27:1343-1350. DOI.
  • Tarzi RM; Sharp PE; McDaid JP; Fossati-Jimack L; Herbert PE; Pusey CD; Cook HT; Warrens AN. (Jan 2012). Mice with defective Fas ligand are protected from crescentic glomerulonephritis. Kidney Int. 81:170-178. DOI.
  • Bellur SS; Troyanov S; Cook HT; Roberts ISD. (1 Aug 2011). Immunostaining findings in IgA nephropathy: correlation with histology and clinical outcome in the Oxford classification patient cohort. NEPHROLOGY DIALYSIS TRANSPLANTATION. 26:2533-2536. DOI.
  • Tarzi RM; Cook HT; Pusey CD. (Jul 2011). Crescentic glomerulonephritis: new aspects of pathogenesis. Semin Nephrol. 31:361-368. DOI.
  • Chan K; Taube D; Roufosse C; Cook T; Brookes P; Goodall D; Galliford J; Cairns T; et alDorling A; Duncan N; Hakim N; Palmer A; Papalois V; Warrens AN; Willicombe M; McLean AG. (15 Oct 2011). Kidney transplantation with minimized maintenance: alemtuzumab induction with tacrolimus monotherapy--an open label, randomized trial. Transplantation. 92:774-780. DOI.
  • Boross P; Arandhara VL; Martin-Ramirez J; Santiago-Raber M-L; Carlucci F; Flierman R; van der Kaa J; Breukel C; et alClaassens JWC; Camps M; Lubberts E; Salvatori D; Rastaldi MP; Ossendorp F; Daha MR; Cook HT; Izui S; Botto M; Verbeek JS. (1 Aug 2011). The Inhibiting Fc Receptor for IgG, Fc gamma RIIB, Is a Modifier of Autoimmune Susceptibility. JOURNAL OF IMMUNOLOGY. 187:1304-1313. DOI.
  • Ling GS; Cook HT; Botto M; Lau YL; Huang FP. (Oct 2011). An essential protective role of IL-10 in the immunological mechanism underlying resistance vs. susceptibility to lupus induction by dendritic cells and dying cells. Rheumatology (Oxford). 50:1773-1784. DOI.
  • Bravou V; McLean AG; Loucaidou M; Cairns TD; Cook HT; Roufosse CA. (Jul 2011). Paraprotein 'zippers'. Kidney Int. 80:126. DOI.
  • Athanasiou Y; Voskarides K; Gale DP; Damianou L; Patsias C; Zavros M; Maxwell PH; Cook HT; et alDemosthenous P; Hadjisavvas A; Kyriacou K; Zouvani I; Pierides A; Deltas C. (1 Jun 2011). Familial C3 Glomerulopathy Associated with CFHR5 Mutations: Clinical Characteristics of 91 Patients in 16 Pedigrees. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 6:1436-1446. Author weblink DOI.
  • Cook HT; Tarzi R; D'Souza Z; Laurent G; Lin WC; Aitman TJ; Mechta-Grigoriou F; Behmoaras J. (Jul 2011). AP-1 transcription factor JunD confers protection from accelerated nephrotoxic nephritis and control podocyte-specific Vegfa expression. Am J Pathol. 179:134-140. DOI.
  • David AL; McIntosh J; Peebles DM; Cook T; Waddington S; Weisz B; Wigley V; Abi-Nader K; et alBoyd M; Davidoff AM; Nathwani AC. (1 Apr 2011). Recombinant Adeno-Associated Virus-Mediated In Utero Gene Transfer Gives Therapeutic Transgene Expression in the Sheep. HUMAN GENE THERAPY. 22:419-426. Author weblink DOI.
  • Sheryanna AM; Smith J; Bhangal G; Barnett A; McClue S; Tam FW; Cook T; Pusey CD. (May 2011). Treatment with a cyclin-dependent kinase inhibitor, seliciclib, is effective in reducing glomerular macrophage numbers and the severity of established experimental glomerulonephritis. Nephrology (Carlton). 16:410-416. DOI.
  • Mansfield N; Hamour S; Habib AM; Tarzi R; Levy J; Griffith M; Cairns T; Cook HT; et alPusey CD; Salama AD. (Oct 2011). Prolonged disease-free remission following rituximab and low-dose cyclophosphamide therapy for renal ANCA-associated vasculitis. Nephrol Dial Transplant. 26:3280-3286. DOI.
  • Pickering M; Cook HT. (May 2011). Complement and glomerular disease: new insights. Curr Opin Nephrol Hypertens. 20:271-277. DOI.
  • Cook HT. (Mar 2011). Focal segmental glomerulosclerosis in IgA nephropathy: a result of primary podocyte injury?. Kidney Int. 79:581-583. DOI.
  • Willicombe M; Brookes P; Santos-Nunez E; Galliford J; Ballow A; Mclean A; Roufosse C; Cook HT; et alDorling A; Warrens AN; Cairns T; Taube D. (Mar 2011). Outcome of patients with preformed donor-specific antibodies following alemtuzumab induction and tacrolimus monotherapy. Am J Transplant. 11:470-477. DOI.
  • Vernon KA; Pickering MC; Cook T. (2011). Experimental models of membranoproliferative glomerulonephritis, including dense deposit disease. Contrib Nephrol. 169:198-210. DOI.
  • Maratou K; Behmoaras J; Fewings C; Srivastava P; D'Souza Z; Smith J; Game L; Cook T; et alAitman T. (Mar 2011). Characterization of the macrophage transcriptome in glomerulonephritis-susceptible and -resistant rat strains. Genes Immun. 12:78-89. DOI.
  • de Jorge EG; Macor P; Paixão-Cavalcante D; Rose KL; Tedesco F; Cook HT; Botto M; Pickering MC. (Jan 2011). The development of atypical hemolytic uremic syndrome depends on complement C5. J Am Soc Nephrol. 22:137-145. DOI.
  • Vernon KA; Gale DP; de Jorge EG; McLean AG; Galliford J; Pierides A; Maxwell PH; Taube D; et alPickering MC; Cook HT. (Jan 2011). Recurrence of complement factor H-related protein 5 nephropathy in a renal transplant. Am J Transplant. 11:152-155. DOI.
  • Gale DP; de Jorge EG; Cook HT; Martinez-Barricarte R; Hadjisavvas A; McLean AG; Pusey CD; Pierides A; et alKyriacou K; Athanasiou Y; Voskarides K; Deltas C; Palmer A; Fremeaux-Bacchi V; Rodriguez de Cordoba S; Maxwell PH; Pickering MC. (4 Sep 2010). Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis. LANCET. 376:794-801. DOI.
  • Fakhouri F; Fremeaux-Bacchi V; Noel L-H; Cook HT; Pickering MC. (1 Aug 2010). C3 glomerulopathy: a new classification. NATURE REVIEWS NEPHROLOGY. 6:494-499. DOI.
  • Stangou M; Bhangal G; Lai PC; Smith J; Keith JC; Boyle JJ; Pusey CD; Cook T; et alTam FW. (Jan 2011). Effect of IL-11 on glomerular expression of TGF-beta and extracellular matrix in nephrotoxic nephritis in Wistar Kyoto rats. J Nephrol. 24:106-111.
  • Behmoaras J; Smith J; D'Souza Z; Bhangal G; Chawanasuntoropoj R; Tam FW; Pusey CD; Aitman TJ; et alCook HT. (Jul 2010). Genetic loci modulate macrophage activity and glomerular damage in experimental glomerulonephritis. J Am Soc Nephrol. 21:1136-1144. DOI.
  • David AL; Abi-Nader KN; Weisz B; Shaw SWS; Themis M; Cook T; Coutelle C; Rodeck CH; et alPeebles DM. (1 Mar 2010). ULTRASONOGRAPHIC DEVELOPMENT OF THE FETAL SHEEP STOMACH AND EVALUATION OF EARLY GESTATION ULTRASOUND-GUIDED IN UTERO I NTRAGASTRIC INJECTION. TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY. 49:23-29. Author weblink.
  • Carlucci F; Fossati-Jimack L; Dumitriu IE; Heidari Y; Walport MJ; Szajna M; Baruah P; Garden OA; et alCook HT; Botto M. (1 Jun 2010). Identification and characterization of a lupus suppressor 129 locus on chromosome 3. J Immunol. 184:6256-6265. DOI.
  • Coppo R; Troyanov S; Camilla R; Hogg RJ; Cattran DC; Cook HT; Feehally J; Roberts ISD; et alAmore A; Alpers CE; Barratt J; Berthoux F; Bonsib S; Bruijn JA; D'Agati V; D'Amico G; Emancipator SN; Emma F; Ferrario F; Fervenza FC; Florquin S; Fogo AB; Geddes CC; Groene HJ; Haas M; Herzenberg AM; Hill PA; Hsu SI; Jennette JC; Joh K; Julian BA; Kawamura T; Lai FM; Li LS; Li PK; Liu ZH; Mezzano S; Schena FP; Tomino Y; Walker PD; Wang H; Weening JJ; Yoshikawa N; Zhang H. (1 May 2010). The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults. KIDNEY INTERNATIONAL. 77:921-927. Author weblink DOI.
  • Tervaert TWC; Mooyaart AL; Amann K; Cohen AH; Cook HT; Drachenberg CB; Ferrario F; Fogo AB; et alHaas M; de Heer E; Joh K; Noel LH; Radhakrishnan J; Seshan SV; Bajema IM; Bruijn JA. (1 Apr 2010). Pathologic Classification of Diabetic Nephropathy. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 21:556-563. Author weblink DOI.
  • Fakhouri F; de Jorge EG; Brune F; Azam P; Cook HT; Pickering MC. (Aug 2010). Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice. Kidney Int. 78:279-286. DOI.
  • Chavele KM; Martinez-Pomares L; Domin J; Pemberton S; Haslam SM; Dell A; Cook HT; Pusey CD; et alGordon S; Salama AD. (May 2010). Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice. J Clin Invest. 120:1469-1478. DOI.
  • Chambers JC; Zhang W; Lord GM; van der Harst P; Lawlor DA; Sehmi JS; Gale DP; Wass MN; et alAhmadi KR; Bakker SJ; Beckmann J; Bilo HJ; Bochud M; Brown MJ; Caulfield MJ; Connell JM; Cook HT; Cotlarciuc I; Davey Smith G; de Silva R; Deng G; Devuyst O; Dikkeschei LD; Dimkovic N; Dockrell M; Dominiczak A; Ebrahim S; Eggermann T; Farrall M; Ferrucci L; Floege J; Forouhi NG; Gansevoort RT; Han X; Hedblad B; Homan van der Heide JJ; Hepkema BG; Hernandez-Fuentes M; Hypponen E; Johnson T; de Jong PE; Kleefstra N; Lagou V; Lapsley M; Li Y; Loos RJ; Luan J; Luttropp K; Maréchal C; Melander O; Munroe PB; Nordfors L; Parsa A; Peltonen L; Penninx BW; Perucha E; Pouta A; Prokopenko I; Roderick PJ; Ruokonen A; Samani NJ; Sanna S; Schalling M; Schlessinger D; Schlieper G; Seelen MA; Shuldiner AR; Sjögren M; Smit JH; Snieder H; Soranzo N; Spector TD; Stenvinkel P; Sternberg MJ; Swaminathan R; Tanaka T; Ubink-Veltmaat LJ; Uda M; Vollenweider P; Wallace C; Waterworth D; Zerres K; Waeber G; Wareham NJ; Maxwell PH; McCarthy MI; Jarvelin MR; Mooser V; Abecasis GR; Lightstone L; Scott J; Navis G; Elliott P; Kooner JS. (May 2010). Genetic loci influencing kidney function and chronic kidney disease. Nat Genet. 42:373-375. DOI.
  • Baruah P; Simpson E; Dumitriu IE; Derbyshire K; Coe D; Addey C; Dyson J; Chai JG; et alCook T; Scott D; Botto M. (Jun 2010). Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance. Eur J Immunol. 40:1758-1767. DOI.
  • Karcz M; Cook HT; Sibbons P; Gray C; Dorling A; Papalois V. (Mar 2010). An ex-vivo model for hypothermic pulsatile perfusion of porcine pancreata: hemodynamic and morphologic characteristics. Exp Clin Transplant. 8:55-60.
  • Carlucci F; Cook HT; Garg A; Pepys MB; Botto M. (Jan 2010). Lack of effect of a single injection of human C-reactive protein on murine lupus or nephrotoxic nephritis. Arthritis Rheum. 62:245-249. DOI.
  • Annear NMP; Cook HT; Atkins M; Pusey CD; Salama AD. (1 Jan 2010). Non-hepatitis virus associated mixed essential cryoglobulinemia. KIDNEY INTERNATIONAL. 77:161-164. Author weblink DOI.
  • Cook HT. (Jan 2010). The origin of renal fibroblasts and progression of kidney disease. Am J Pathol. 176:22-24. DOI.
  • Smith J; McDaid JP; Bhangal G; Chawanasuntorapoj R; Masuda ES; Cook HT; Pusey CD; Tam FW. (Feb 2010). A spleen tyrosine kinase inhibitor reduces the severity of established glomerulonephritis. J Am Soc Nephrol. 21:231-236. DOI.
  • Shea-Simonds P; Cairns TD; Roufosse C; Cook T; Vyse TJ. (1 Dec 2009). Lupus podocytopathy. RHEUMATOLOGY. 48:1616-1618. Author weblink DOI.
  • Behmoaras J; Cook HT; Pusey CD. (1 Oct 2009). Kallikreins: unravelling the genetics of autoimmune glomerulonephritis. NEPHROLOGY DIALYSIS TRANSPLANTATION. 24:2987-2989. Author weblink DOI.
  • Roberts ISD; Cook HT; Troyanov S; Alpers CE; Amore A; Barratt J; Berthoux F; Bonsib S; et alBruijn JA; Cattran DC; Coppo R; D'Agati V; D'Amico G; Emancipator S; Emma F; Feehally J; Ferrario F; Fervenza FC; Florquin S; Fogo A; Geddes CC; Groene H-J; Haas M; Herzenberg AM; Hill PA; Hogg RJ; Hsu SI; Jennette JC; Joh K; Julian BA; Kawamura T; Lai FM; Li L-S; Li PKT; Liu Z-H; Mackinnon B; Mezzano S; Schena FP; Tomino Y; Walker PD; Wang H; Weening JJ; Yoshikawa N; Zhang H. (1 Sep 2009). The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. KIDNEY INTERNATIONAL. 76:546-556. Author weblink DOI.
  • Cattran DC; Coppo R; Cook HT; Feehally J; Roberts ISD; Troyanov S; Alpers CE; Amore A; et alBarratt J; Berthoux F; Bonsib S; Bruijn JA; D'Agati V; D'Amico G; Emancipator S; Emma F; Ferrario F; Fervenza FC; Florquin S; Fogo A; Geddes CC; Groene H-J; Haas M; Herzenberg AM; Hill PA; Hogg RJ; Hsu SI; Jennette JC; Joh K; Julian BA; Kawamura T; Lai FM; Leung CB; Li L-S; Li PKT; Liu Z-H; Mackinnon B; Mezzano S; Schena FP; Tomino Y; Walker PD; Wang H; Weening JJ; Yoshikawa N; Zhang H. (1 Sep 2009). The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. KIDNEY INTERNATIONAL. 76:534-545. Author weblink DOI.
  • Chavele K-M; Martinez-Pomares L; Gordon S; Cook T; Pusey C; Salama A. (1 Jun 2009). Circulating mannose receptor is elevated in acute ANCA-associated vasculitis and contributes in the development of experimental glomerulonephritis. APMIS. 117:154-154. Author weblink.
  • Gleeson CM; Levy JB; Cook HT; Francis ND; Robson A; Pope FM. (Dec 2009). An atypical cutaneous presentation of vasculitis with features of Churg-Strauss syndrome, associated with anti-neutrophil cytoplasmic antibodies and anti-glomerular basement membrane antibodies. Clin Exp Dermatol. 34:e577-e580. DOI.
  • Paixão-Cavalcante D; Hanson S; Botto M; Cook HT; Pickering MC. (Jun 2009). Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phase. Mol Immunol. 46:1942-1950. DOI.
  • Taylor SR; Turner CM; Elliott JI; McDaid J; Hewitt R; Smith J; Pickering MC; Whitehouse DL; et alCook HT; Burnstock G; Pusey CD; Unwin RJ; Tam FW. (Jun 2009). P2X7 deficiency attenuates renal injury in experimental glomerulonephritis. J Am Soc Nephrol. 20:1275-1281. DOI.
  • Baruah P; Dumitriu IE; Malik TH; Cook HT; Dyson J; Scott D; Simpson E; Botto M. (9 Apr 2009). C1q enhances IFN-gamma production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells. BLOOD. 113:3485-3493. Author weblink DOI.
  • Roufosse CA; Cook HT. (May 2009). Pathological predictors of prognosis in immunoglobulin A nephropathy: a review. Curr Opin Nephrol Hypertens. 18:212-219. DOI.
  • Little MA; Smyth L; Salama AD; Mukherjee S; Smith J; Haskard D; Nourshargh S; Cook HT; et alPusey CD. (Apr 2009). Experimental autoimmune vasculitis: an animal model of anti-neutrophil cytoplasmic autoantibody-associated systemic vasculitis. Am J Pathol. 174:1212-1220. DOI.
  • Yee MS; Pavitt DV; Richmond W; Cook HT; McLean AG; Valabhji J; Elkeles RS. (Aug 2009). Changes in lipoprotein profile and urinary albumin excretion in familial LCAT deficiency with lipid lowering therapy. Atherosclerosis. 205:528-532. DOI.
  • Paixao-Cavalcante D; Botto M; Cook HT; Pickering MC. (1 Feb 2009). Shiga toxin-2 results in renal tubular injury but not thrombotic microangiopathy in heterozygous factor H-deficient mice. CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 155:339-347. Author weblink DOI.
  • Galliford J; Charif R; Chan KK; Loucaidou M; Cairns T; Cook HT; Dorling A; Hakim N; et alMcLean A; Papalois V; Malde R; Regan F; Redman M; Warrens AN; Taube D. (15 Oct 2008). ABO Incompatible Living Renal Transplantation With a Steroid Sparing Protocol. TRANSPLANTATION. 86:901-906. Author weblink DOI.
  • Heidari Y; Fossati-Jimack L; Carlucci F; Walport MJ; Cook HT; Botto M. (Jan 2009). A lupus-susceptibility C57BL/6 locus on chromosome 3 (Sle18) contributes to autoantibody production in 129 mice. Genes Immun. 10:47-55. DOI.
  • David AL; Torondel B; Zachary I; Wigley V; Nader KA; Mehta V; Buckley SMK; Cook T; et alBoyd M; Rodeck CH; Martin J; Peebles DM. (1 Oct 2008). Local delivery of VEGF adenovirus to the uterine artery increases vasorelaxation and uterine blood flow in the pregnant sheep. GENE THERAPY. 15:1344-1350. Author weblink DOI.
  • Roufosse C; Cook HT. (1 Jan 2008). Stem cells and renal regeneration. NEPHRON EXPERIMENTAL NEPHROLOGY. 109:E39-E45. Author weblink DOI.
  • Fang T-C; Otto WR; Jeffery R; Hunt T; Alison MR; Cook HT; Wright NA; Poulsom R. (1 Aug 2008). Exogenous bone marrow cells do not rescue non-irradiated mice from acute renal tubular damage caused by HgCl(2), despite establishment of chimaerism and cell proliferation in bone marrow and spleen. CELL PROLIFERATION. 41:592-606. Author weblink DOI.
  • Fossati-Jimack L; Cortes-Hernandez J; Norsworthy PJ; Cook HT; Walport MJ; Botto M. (1 Jul 2008). Regulation of B cell tolerance by 129-derived chromosome 1 loci in C57BL/6 mice. ARTHRITIS AND RHEUMATISM. 58:2131-2141. Author weblink DOI.
  • Behmoaras J; Bhangal G; Smith J; McDonald K; Mutch B; Lai PC; Domin J; Game L; et alSalama A; Foxwell BM; Pusey CD; Cook HT; Aitman TJ. (1 May 2008). Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility. NATURE GENETICS. 40:553-559. Author weblink DOI.
  • Guillot PV; Cook HT; Pusey CD; Fisk NM; Harten S; Moss J; Shore I; Bou-Gharios G. (Apr 2008). Transplantation of human fetal mesenchymal stem cells improves glomerulopathy in a collagen type I alpha 2-deficient mouse. J Pathol. 214:627-636. DOI.
  • Salama AD; Cook HT; Pusey CD; Pepper RJ. (1 Mar 2008). A case of treated ANCA-associated vasculitis with recurrent renal failure. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 3:637-645. Author weblink DOI.
  • Philibert D; Cattran D; Cook T. (1 Jan 2008). Clinicopathologic correlation in IgA nephropathy. SEMINARS IN NEPHROLOGY. 28:10-17. Author weblink DOI.
  • Rose KL; Paixao-Cavalcante D; Fish J; Manderson AP; Malik TH; Bygrave AE; Lin T; Sacks SH; et alWalport MJ; Cook HT; Botto M; Pickering MC. (1 Feb 2008). Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. JOURNAL OF CLINICAL INVESTIGATION. 118:608-618. Author weblink DOI.
  • Hill P; Shukla D; Tran MG; Aragones J; Cook HT; Carmeliet P; Maxwell PH. (Jan 2008). Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury. J Am Soc Nephrol. 19:39-46. DOI.
  • Pickering MC; Cook HT. (Feb 2008). Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals. Clin Exp Immunol. 151:210-230. DOI.
  • Satchell SC; Buchatska O; Khan SB; Bhangal G; Tasman CH; Saleem MA; Baker DP; Lobb RR; et alSmith J; Cook HT; Mathieson PW; Pusey CD. (Nov 2007). Interferon-beta reduces proteinuria in experimental glomerulonephritis. J Am Soc Nephrol. 18:2875-2884. DOI.
  • Rose KL; Paixao-Cavalcante D; Fish J; Manderson AP; Malik T; Bygrave AE; Lin T; Sacks SH; et alWalport MJ; Cook HT; Botto M; Pickering MC. (1 Sep 2007). Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. MOLECULAR IMMUNOLOGY. 44:3924-3924. Author weblink DOI.
  • Fossati-Jimack L; Cortes-Hernandez J; Norsworthy PJ; Walport MJ; Cook HT; Botto M. (Feb 2008). C1q deficiency promotes the production of transgenic-derived IgM and IgG3 autoantibodies in anti-DNA knock-in transgenic mice. Mol Immunol. 45:787-795. DOI.
  • Smith RJ; Alexander J; Barlow PN; Botto M; Cassavant TL; Cook HT; de Córdoba SR; Hageman GS; et alJokiranta TS; Kimberling WJ; Lambris JD; Lanning LD; Levidiotis V; Licht C; Lutz HU; Meri S; Pickering MC; Quigg RJ; Rops AL; Salant DJ; Sethi S; Thurman JM; Tully HF; Tully SP; van der Vlag J; Walker PD; Würzner R; Zipfel PF; Dense Deposit Disease Focus Group. (Sep 2007). New approaches to the treatment of dense deposit disease. J Am Soc Nephrol. 18:2447-2456. DOI.
  • Poulsom R; Alison MR; Cook T; Jeffery R; Ryan E; Forbes SJ; Hunt T; Wyles S; et alWright NA. (Jun 2003). Bone marrow stem cells contribute to healing of the kidney. J AM SOC NEPHROL. 14:S48-S54.
  • Weisz B; David AL; Gregory LG; Perocheau D; Ruthe A; Waddington SN; Themis M; Cook T; et alCoutelle C; Rodeck CH; Peebles DM. (Sep 2005). Targeting the respiratory muscles of fetal sheep for prenatal gene therapy for Duchenne muscular dystrophy. AM J OBSTET GYNECOL. 193:1105-1109.
  • David AL; Themis M; Cook T; Coutelle C; Rodeck C. (2001). Fetal gene therapy. Ultrasound Rev Obstet Gynecol. 1, 1:14-27.
  • Fanciulli M; Norsworthy PJ; Petretto E; Dong R; Harper L; Kamesh L; Heward JM; Gough SC; et alde Smith A; Blakemore AI; Froguel P; Owen CJ; Pearce SH; Teixeira L; Guillevin L; Graham DS; Pusey CD; Cook HT; Vyse TJ; Aitman TJ. (Jun 2007). FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity. Nat Genet. 39:721-723. DOI.
  • Pickering MC; de Jorge EG; Martinez-Barricarte R; Recalde S; Garcia-Layana A; Rose KL; Moss J; Walport MJ; et alCook HT; de Córdoba SR; Botto M. (11 Jun 2007). Spontaneous hemolytic uremic syndrome triggered by complement factor H lacking surface recognition domains. J Exp Med. 204:1249-1256. DOI.
  • Cook HT. (2007). Interpretation of renal biopsies in IgA nephropathy. Contrib Nephrol. 157:44-49. DOI.
  • Cook T. (Jun 2007). A new pathologic scoring system for renal calcineurin-inhibitor toxicity correlates with future graft function. Nat Clin Pract Nephrol. 3:316-317. DOI.
  • Smith J; Lai PC; Behmoaras J; Roufosse C; Bhangal G; McDaid JP; Aitman T; Tam FW; et alPusey CD; Cook HT. (Jun 2007). Genes expressed by both mesangial cells and bone marrow-derived cells underlie genetic susceptibility to crescentic glomerulonephritis in the rat. J Am Soc Nephrol. 18:1816-1823. DOI.
  • Carlucci F; Cortes-Hernandez J; Fossati-Jimack L; Bygrave AE; Walport MJ; Vyse TJ; Cook HT; Botto M. (15 Feb 2007). Genetic dissection of spontaneous autoimmunity driven by 129-derived chromosome 1 Loci when expressed on C57BL/6 mice. J Immunol. 178:2352-2360.
  • Turner CM; Tam FWK; Lai P-C; Tarzi RM; Burnstock G; Pusey CD; Cook HT; Unwin RJ. (1 Feb 2007). Increased expression of the pro-apoptotic ATP-sensitive P2X(7) receptor in experimental and human glomerulonephritis. NEPHROLOGY DIALYSIS TRANSPLANTATION. 22:386-395. DOI.
  • Sheryanna A; Bhangal G; McDaid J; Smith J; Manning A; Foxwell BM; Feldmann M; Cook HT; et alPusey CD; Tam FW. (Apr 2007). Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1beta or IL-6. J Am Soc Nephrol. 18:1167-1179. DOI.
  • Poulsom R; Prodromidi EI; Pusey CD; Cook HT. (1 Dec 2006). Cell therapy for renal regeneration-time for some joined-up thinking?. NEPHROLOGY DIALYSIS TRANSPLANTATION. 21:3349-3353. Author weblink DOI.
  • Cobb BS; Hertweck A; Smith J; O'Connor E; Graf D; Cook T; Smale ST; Sakaguchi S; et alLivesey FJ; Fisher AG; Merkenschlager M. (30 Oct 2006). A role for Dicer in immune regulation. J Exp Med. 203:2519-2527. DOI.
  • Heidari Y; Bygrave AE; Rigby RJ; Rose KL; Walport MJ; Cook HT; Vyse TJ; Botto M. (Oct 2006). Identification of chromosome intervals from 129 and C57BL/6 mouse strains linked to the development of systemic lupus erythematosus. Genes Immun. 7:592-599. DOI.
  • Turnberg D; Lewis M; Moss J; Xu Y; Botto M; Cook HT. (15 Sep 2006). Complement activation contributes to both glomerular and tubulointerstitial damage in adriamycin nephropathy in mice. J Immunol. 177:4094-4102.
  • David AL; Weisz B; Gregory L; Themis M; Cook T; Roubliova X; Deprest J; Coutelle C; et alRodeck CH; Peebles DM. (1 Jul 2006). Ultrasound-guided injection and occlusion of the trachea in fetal sheep. ULTRASOUND IN OBSTETRICS & GYNECOLOGY. 28:82-88. Author weblink DOI.
  • David AL; Peebles DM; Gregory L; Waddington SN; Themis M; Weisz B; Ruthe A; Lawrence L; et alCook T; Rodeck CH; Coutelle C. (1 Jul 2006). Clinically applicable procedure for gene delivery to fetal gut by ultrasound-guided gastric injection: Toward prenatal prevention of early-onset intestinal diseases. HUMAN GENE THERAPY. 17:767-779. Author weblink DOI.
  • Prodromidi EI; Poulsom R; Jeffery R; Roufosse CA; Pollard PJ; Pusey CD; Cook HT. (Nov 2006). Bone marrow-derived cells contribute to podocyte regeneration and amelioration of renal disease in a mouse model of Alport syndrome. Stem Cells. 24:2448-2455. DOI.
  • Cook HT; Botto M. (1 Jun 2006). Mechanisms of disease: the complement system and the pathogenesis of systemic lupus erythematosus. NATURE CLINICAL PRACTICE RHEUMATOLOGY. 2:330-337. Author weblink DOI.
  • Pickering MC; Warren J; Rose KL; Carlucci F; Wang Y; Walport MJ; Cook HT; Botto M. (20 Jun 2006). Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice. Proc Natl Acad Sci U S A. 103:9649-9654. DOI.
  • Manderson AP; Carlucci F; Lachmann PJ; Lazarus RA; Festenstein RJ; Cook HT; Walport MJ; Botto M. (2006). The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus. Arthritis Res Ther. 8:R68. DOI.
  • Aitman TJ; Dong R; Vyse TJ; Norsworthy PJ; Johnson MD; Smith J; Mangion J; Roberton-Lowe C; et alMarshall AJ; Petretto E; Hodges MD; Bhangal G; Patel SG; Sheehan-Rooney K; Duda M; Cook PR; Evans DJ; Domin J; Flint J; Boyle JJ; Pusey CD; Cook HT. (16 Feb 2006). Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature. 439:851-855. DOI.
  • Roufosse C; Bou-Gharios G; Prodromidi E; Alexakis C; Jeffery R; Khan S; Otto WR; Alter J; et alPoulsom R; Cook HT. (Mar 2006). Bone marrow-derived cells do not contribute significantly to collagen I synthesis in a murine model of renal fibrosis. J Am Soc Nephrol. 17:775-782. DOI.
  • Hamdulay SS; Cook HT; Strickland N; Davies KA; Mason JC. (Apr 2007). Peritoneal mesothelioma: an unusual cause of an acute phase response presenting to the rheumatologist. Clin Rheumatol. 26:584-586. DOI.
  • CATTELL V; COOK HT. (1 Sep 1993). NITRIC-OXIDE - ROLE IN THE PHYSIOLOGY AND PATHOLOGY OF THE GLOMERULUS. EXPERIMENTAL NEPHROLOGY. 1:265-280. Author weblink.
  • Cook HT; Cattell V. (1 Oct 1996). Role of nitric oxide in immune-mediated diseases. CLINICAL SCIENCE. 91:375-384. Author weblink.
  • Marshall BG; Wangoo A; Shaw RJ; Cook HT. (1 Jun 1997). Growth factors and granulomatous inflammation - Reply. THORAX. 52:588-588. Author weblink.
  • Ehrenstein MR; Cook HT; Neuberger MS. (3 Apr 2000). Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies. JOURNAL OF EXPERIMENTAL MEDICINE. 191:1253-1257. Author weblink DOI.
  • Lawman S; Mauri C; Jury EC; Cook HT; Ehrenstein MR. (15 Dec 2004). Atorvastatin inhibits autoreactive B cell activation and delays lupus development in New Zealand black/white F(1) mice. JOURNAL OF IMMUNOLOGY. 173:7641-7646. Author weblink.
  • Appel GB; Cook HT; Hageman G; Jennette JC; Kashgarian M; Kirschfink M; Lambris JD; Lanning L; et alLutz HU; Meri S; Rose NR; Salant DJ; Sethi S; Smith RJH; Smoyer W; Tully HF; Tully SP; Walker P; Welsh M; Wurzner R; Zipfel PF. (1 May 2005). Membranoproliferative glomerulonephritis type II (dense deposit disease): An update. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 16:1392-1403. Author weblink DOI.
  • Elliot V; Cairns T; Cook HT. (Jan 2006). Evolution of lesions over 10 years in a patient with SLE: flowchart approach to the new International Society of Nephrology (ISN)/Renal Pathology Society (RPS) classification of lupus nephritis. Am J Kidney Dis. 47:184-190. DOI.
  • Little MA; Bhangal G; Smyth CL; Nakada MT; Cook HT; Nourshargh S; Pusey CD. (Jan 2006). Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis. J Am Soc Nephrol. 17:160-169. DOI.
  • Kodama T; Tan PH; Offiah I; Partridge T; Cook T; George AJ; Blomley MJ. (Dec 2005). Delivery of oligodeoxynucleotides into human saphenous veins and the adjunct effect of ultrasound and microbubbles. Ultrasound Med Biol. 31:1683-1691. DOI.
  • Trendelenburg M; Fossati-Jimack L; Cortes-Hernandez J; Turnberg D; Lewis M; Izui S; Cook HT; Botto M. (15 Nov 2005). The role of complement in cryoglobulin-induced immune complex glomerulonephritis. J Immunol. 175:6909-6914.
  • Little MA; Smyth CL; Yadav R; Ambrose L; Cook HT; Nourshargh S; Pusey CD. (15 Sep 2005). Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo. BLOOD. 106:2050-2058. Author weblink DOI.
  • Khan SB; Cook HT; Bhangal G; Smith J; Tam FW; Pusey CD. (May 2005). Antibody blockade of TNF-alpha reduces inflammation and scarring in experimental crescentic glomerulonephritis. Kidney Int. 67:1812-1820. DOI.
  • Turnberg D; Cook HT. (May 2005). Complement and glomerulonephritis: new insights. Curr Opin Nephrol Hypertens. 14:223-228.
  • Lai PC; Smith J; Bhangal G; Chaudhry KA; Chaudhry AN; Keith JC; Tam FWK; Pusey CD; et alCook HT. (1 Jan 2005). Interleukin-11 reduces renal injury and glomerular NF-Kappa B activity in murine experimental glomerulonephritis. NEPHRON EXPERIMENTAL NEPHROLOGY. 101:E146-E154. Author weblink DOI.
  • Cortes-Hernandez J; Fossati-Jimack L; Petry F; Loos M; Izui S; Walport MJ; Cook HT; Botto M. (Dec 2004). Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice. Eur J Immunol. 34:3713-3722. DOI.
  • Waddington SN; Nivsarkar MS; Mistry AR; Buckley SM; Kemball-Cook G; Mosley KL; Mitrophanous K; Radcliffe P; et alHolder MV; Brittan M; Georgiadis A; Al-Allaf F; Bigger BW; Gregory LG; Cook HT; Ali RR; Thrasher A; Tuddenham EG; Themis M; Coutelle C. (1 Nov 2004). Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy. Blood. 104:2714-2721. DOI.
  • Tam FW; Sanders JS; George A; Hammad T; Miller C; Dougan T; Cook HT; Kallenberg CG; et alGaskin G; Levy JB; Pusey CD. (Nov 2004). Urinary monocyte chemoattractant protein-1 (MCP-1) is a marker of active renal vasculitis. Nephrol Dial Transplant. 19:2761-2768. DOI.
  • Turnberg D; Botto M; Lewis M; Zhou W; Sacks SH; Morgan BP; Walport MJ; Cook HT. (Sep 2004). CD59a deficiency exacerbates ischemia-reperfusion injury in mice. Am J Pathol. 165:825-832. DOI.
  • Bygrave AE; Rose KL; Cortes-Hernandez J; Warren J; Rigby RJ; Cook HT; Walport MJ; Vyse TJ; et alBotto M. (Aug 2004). Spontaneous autoimmunity in 129 and C57BL/6 mice-implications for autoimmunity described in gene-targeted mice. PLoS Biol. 2:E243. DOI.
  • Waddington SN; Buckley SM; Bernloehr C; Bossow S; Ungerechts G; Cook T; Gregory L; Rahim A; et alThemis M; Neubert WJ; Coutelle C; Lauer UM; Bitzer M. (Apr 2004). Reduced toxicity of F-deficient Sendai virus vector in the mouse fetus. Gene Ther. 11:599-608. DOI.
  • Mirenda V; Berton I; Read J; Cook T; Smith J; Dorling A; Lechler RI. (Apr 2004). Modified dendritic cells coexpressing self and allogeneic major histocompatability complex molecules: an efficient way to induce indirect pathway regulation. J Am Soc Nephrol. 15:987-997.
  • Lord GM; Hollstein M; Arlt VM; Roufosse C; Pusey CD; Cook T; Schmeiser HH. (1 Apr 2004). DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy. AMERICAN JOURNAL OF KIDNEY DISEASES. 43. Author weblink DOI.
  • Weening JJ; D'Agati VD; Schwartz MM; Seshan SV; Alpers CE; Appel GB; Balow JE; Bruijn JA; et alCook T; Ferrario F; Fogo AB; Ginzler EM; Hebert L; Hill G; Hill P; Jennette JC; Kong NC; Lesavre P; Lockshin M; Looi LM; Makino H; Moura LA; Nagata M. (Feb 2004). The classification of glomerulonephritis in systemic lupus erythematosus revisited. J Am Soc Nephrol. 15:241-250.
  • Tarzi RM; Cook HT; Jackson I; Pusey CD; Lord GM. (Feb 2004). Leptin-deficient mice are protected from accelerated nephrotoxic nephritis. Am J Pathol. 164:385-390. DOI.
  • Weening JJ; D'Agati VD; Schwartz MM; Seshan SV; Alpers CE; Appel GB; Balow JE; Bruijn JA; et alCook T; Ferrario F; Fogo AB; Ginzler EM; Hebert L; Hill G; Hill P; Jennette JC; Kong NC; Lesavre P; Lockshin M; Looi LM; Makino H; Moura LA; Nagata M; International Society of Nephrology Working Group on the Classification of Lupus Nephritis; Renal Pathology Society Working Group on the Classification of Lupus Nephritis. (Feb 2004). The classification of glomerulonephritis in systemic lupus erythematosus revisited. Kidney Int. 65:521-530. DOI.
  • Peebles D; Gregory LG; David A; Themis M; Waddington SN; Knapton HJ; Miah M; Cook T; et alLawrence L; Nivsarkar M; Rodeck C; Coutelle C. (Jan 2004). Widespread and efficient marker gene expression in the airway epithelia of fetal sheep after minimally invasive tracheal application of recombinant adenovirus in utero. Gene Ther. 11:70-78. DOI.
  • Coutelle C; Themis M; Waddington S; Gregory L; Nivsarkar M; Buckley S; Cook T; Rodeck C; et alPeebles D; David A. (Oct 2003). The hopes and fears of in utero gene therapy for genetic disease--a review. Placenta. 24 Suppl B:S114-S121.
  • Robson MG; Cook HT; Pusey CD; Walport MJ; Davies KA. (Sep 2003). Antibody-mediated glomerulonephritis in mice: the role of endotoxin, complement and genetic background. Clin Exp Immunol. 133:326-333.
  • Turnberg D; Botto M; Warren J; Morgan BP; Walport MJ; Cook HT. (Sep 2003). CD59a deficiency exacerbates accelerated nephrotoxic nephritis in mice. J Am Soc Nephrol. 14:2271-2279.
  • Dupont PJ; Dooldeniya M; Cook T; Warrens AN. (Sep 2003). Role of duplex Doppler sonography in diagnosis of acute allograft dysfunction-time to stop measuring the resistive index?. Transpl Int. 16:648-652. DOI.
  • Waddington SN; Mitrophanous KA; Ellard FM; Buckley SM; Nivsarkar M; Lawrence L; Cook HT; Al-Allaf F; et alBigger B; Kingsman SM; Coutelle C; Themis M. (Aug 2003). Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice. Gene Ther. 10:1234-1240. DOI.
  • Tarzi RM; Davies KA; Claassens JW; Verbeek JS; Walport MJ; Cook HT. (May 2003). Both Fcgamma receptor I and Fcgamma receptor III mediate disease in accelerated nephrotoxic nephritis. Am J Pathol. 162:1677-1683.
  • Clarke HC; Kocher HM; Khwaja A; Kloog Y; Cook HT; Hendry BM. (Apr 2003). Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis. J Am Soc Nephrol. 14:848-854.
  • David A; Cook T; Waddington S; Peebles D; Nivsarkar M; Knapton H; Miah M; Dahse T; et alNoakes D; Schneider H; Rodeck C; Coutelle C; Themis M. (1 Mar 2003). Ultrasound-guided percutaneous delivery of adenoviral vectors encoding the beta-galactosidase and human factor IX genes to early gestation fetal sheep in utero. Hum Gene Ther. 14:353-364. DOI.
  • Tarzi RM; Cook HT. (2003). Role of Fcgamma receptors in glomerulonephritis. Nephron Exp Nephrol. 95:e7-12. DOI.
  • Khan SB; Allen AR; Bhangal G; Smith J; Lobb RR; Cook HT; Pusey CD. (2003). Blocking VLA-4 prevents progression of experimental crescentic glomerulonephritis. Nephron Exp Nephrol. 95:e100-e110. DOI.
  • Cortes-Hernandez J; Fossati-Jimack L; Carugati A; Potter PK; Walport MJ; Cook HT; Botto M. (Dec 2002). Murine glomerular mesangial cell uptake of apoptotic cells is inefficient and involves serum-mediated but complement-independent mechanisms. Clin Exp Immunol. 130:459-466.
  • Tarzi RM; Davies KA; Robson MG; Fossati-Jimack L; Saito T; Walport MJ; Cook HT. (Dec 2002). Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells. Kidney Int. 62:2087-2096. DOI.
  • Cook HT; Khan SB; Allen A; Bhangal G; Smith J; Lobb RR; Pusey CD. (Oct 2002). Treatment with an antibody to VLA-1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescentic glomerulonephritis. Am J Pathol. 161:1265-1272. DOI.
  • Pickering MC; Cook HT; Warren J; Bygrave AE; Moss J; Walport MJ; Botto M. (Aug 2002). Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H. Nat Genet. 31:424-428. DOI.
  • Salama AD; Dougan T; Levy JB; Cook HT; Morgan SH; Naudeer S; Maidment G; George AJ; et alEvans D; Lightstone L; Pusey CD. (Jun 2002). Goodpasture's disease in the absence of circulating anti-glomerular basement membrane antibodies as detected by standard techniques. Am J Kidney Dis. 39:1162-1167. DOI.
  • Gladman MA; MacDonald D; Webster JJ; Cook T; Williams G. (Apr 2002). Renal cell carcinoma in pregnancy. J R Soc Med. 95:199-201.
  • Mitchell DA; Pickering MC; Warren J; Fossati-Jimack L; Cortes-Hernandez J; Cook HT; Botto M; Walport MJ. (1 Mar 2002). C1q deficiency and autoimmunity: the effects of genetic background on disease expression. J Immunol. 168:2538-2543.
  • Cronin AJ; Maidment G; Cook T; Kite GC; Simmonds MS; Pusey CD; Lord GM. (Mar 2002). Aristolochic acid as a causative factor in a case of Chinese herbal nephropathy. Nephrol Dial Transplant. 17:524-525.
  • Reynolds J; Norgan VA; Bhambra U; Smith J; Cook HT; Pusey CD. (Feb 2002). Anti-CD8 monoclonal antibody therapy is effective in the prevention and treatment of experimental autoimmune glomerulonephritis. J Am Soc Nephrol. 13:359-369.
  • Baker RJ; Hernandez-Fuentes MP; Brookes PA; Chaudhry AN; Cook HT; Lechler RI. (15 Dec 2001). Loss of direct and maintenance of indirect alloresponses in renal allograft recipients: implications for the pathogenesis of chronic allograft nephropathy. J Immunol. 167:7199-7206.
  • Lord GM; Cook T; Arlt VM; Schmeiser HH; Williams G; Pusey CD. (3 Nov 2001). Urothelial malignant disease and Chinese herbal nephropathy. Lancet. 358:1515-1516.
  • Lai PC; Cook HT; Smith J; Keith JC; Pusey CD; Tam FW. (Nov 2001). Interleukin-11 attenuates nephrotoxic nephritis in Wistar Kyoto rats. J Am Soc Nephrol. 12:2310-2320.
  • Marshall BG; Wangoo A; O'Gaora P; Cook HT; Shaw RJ; Young DB. (Nov 2001). Enhanced antimycobacterial response to recombinant Mycobacterium bovis BCG expressing latency-associated peptide. Infect Immun. 69:6676-6682. DOI.
  • Salama AD; Delikouras A; Pusey CD; Cook HT; Bhangal G; Lechler RI; Dorling A. (Sep 2001). Transplant accommodation in highly sensitized patients: a potential role for Bcl-xL and alloantibody. Am J Transplant. 1:260-269.
  • Poulsom R; Forbes SJ; Hodivala-Dilke K; Ryan E; Wyles S; Navaratnarasah S; Jeffery R; Hunt T; et alAlison M; Cook T; Pusey C; Wright NA. (Sep 2001). Bone marrow contributes to renal parenchymal turnover and regeneration. J Pathol. 195:229-235. DOI.
  • Pickering MC; Fischer S; Lewis MR; Walport MJ; Botto M; Cook HT. (Jul 2001). Ultraviolet-radiation-induced keratinocyte apoptosis in C1q-deficient mice. J Invest Dermatol. 117:52-58. DOI.
  • Robson MG; Cook HT; Botto M; Taylor PR; Busso N; Salvi R; Pusey CD; Walport MJ; et alDavies KA. (1 Jun 2001). Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice. J Immunol. 166:6820-6828.
  • Ball S; Lloyd J; Cairns T; Cook T; Palmer A; Cattell V; Taube D. (Apr 2001). Why is there so much end-stage renal failure of undetermined cause in UK Indo-Asians?. QJM. 94:187-193.
  • Wangoo A; Sparer T; Brown IN; Snewin VA; Janssen R; Thole J; Cook HT; Shaw RJ; et alYoung DB. (1 Mar 2001). Contribution of Th1 and Th2 cells to protection and pathology in experimental models of granulomatous lung disease. J Immunol. 166:3432-3439.
  • Cook HT. (2001). Complement deficiencies, lupus and apoptosis. Adv Nephrol Necker Hosp. 31:29-41.
  • Coutelle C; Themis M; Schneider H; Kiserud T; Cook T; Douar AM; Hanson M; Pavirani A; et alRodeck C. (2001). Fetal somatic gene therapy--a preventive approach to the treatment of genetic disease: the case for. Ernst Schering Res Found Workshop. 99-114.
  • Dupont PJ; Lightstone L; Clutterbuck EJ; Gaskin G; Pusey CD; Cook T; Warrens AN. (28 Oct 2000). Lesson of the week: cholesterol emboli syndrome. BMJ. 321:1065-1067.
  • Taylor PR; Carugati A; Fadok VA; Cook HT; Andrews M; Carroll MC; Savill JS; Henson PM; et alBotto M; Walport MJ. (7 Aug 2000). A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med. 192:359-366.
  • Wangoo A; Brown IN; Marshall BG; Cook HT; Young DB; Shaw RJ. (Jan 2000). Bacille Calmette-Guérin (BCG)-associated inflammation and fibrosis: modulation by recombinant BCG expressing interferon-gamma (IFN-gamma). Clin Exp Immunol. 119:92-98.
  • Lord GM; Tagore R; Cook T; Gower P; Pusey CD. (7 Aug 1999). Nephropathy caused by Chinese herbs in the Uh. LANCET. 354:481-482. Author weblink DOI.
  • Tam FW; Smith J; Morel D; Karkar AM; Thompson EM; Cook HT; Pusey CD. (Jul 1999). Development of scarring and renal failure in a rat model of crescentic glomerulonephritis. Nephrol Dial Transplant. 14:1658-1666.
  • Themis M; Schneider H; Kiserud T; Cook T; Adebakin S; Jezzard S; Forbes S; Hanson M; et alPavirani A; Rodeck C; Coutelle C. (Jul 1999). Successful expression of beta-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein. Gene Ther. 6:1239-1248. DOI.
  • Clarke HC; Cook HT; Hendry BM. (1 Jul 1999). Gene therapy for renal fibroblasts. NEPHROLOGY DIALYSIS TRANSPLANTATION. 14:1615-1617. Author weblink DOI.
  • Bickerstaff MC; Botto M; Hutchinson WL; Herbert J; Tennent GA; Bybee A; Mitchell DA; Cook HT; et alButler PJ; Walport MJ; Pepys MB. (Jun 1999). Serum amyloid P component controls chromatin degradation and prevents antinuclear autoimmunity. Nat Med. 5:694-697. DOI.
  • Mitchell DA; Taylor PR; Cook HT; Moss J; Bygrave AE; Walport MJ; Botto M. (15 May 1999). Cutting edge: C1q protects against the development of glomerulonephritis independently of C3 activation. J Immunol. 162:5676-5679.
  • Allen AR; McHale J; Smith J; Cook HT; Karkar A; Haskard DO; Lobb RR; Pusey CD. (1 May 1999). Endothelial expression of VCAM-1 in experimental crescentic nephritis and effect of antibodies to very late antigen-4 or VCAM-1 on glomerular injury. J Immunol. 162:5519-5527.
  • Cook HT; Singh SJ; Wembridge DE; Smith J; Tam FW; Pusey CD. (Apr 1999). Interleukin-4 ameliorates crescentic glomerulonephritis in Wistar Kyoto rats. Kidney Int. 55:1319-1326. DOI.
  • Waddington SN; Mosley K; Cook HT; Tam FW; Cattell V. (9 Jun 1998). Arginase AI is upregulated in acute immune complex-induced inflammation. Biochem Biophys Res Commun. 247:84-87. DOI.
  • Botto M; Dell'Agnola C; Bygrave AE; Thompson EM; Cook HT; Petry F; Loos M; Pandolfi PP; et alWalport MJ. (May 1998). Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet. 19:56-59. DOI.
  • Robson MG; Cook HT; Botto M; Pusey CD; Walport MJ; Davies KA. (1 Apr 1998). Delayed resolution of inflammation in heterologous nephrotoxic nephritis in Clq deficient mice. MOLECULAR IMMUNOLOGY. 35:343-343. DOI.
  • Cattell V; Cook HT; Ebrahim H; Waddington SN; Wei XQ; Assmann KJ; Liew FY. (Apr 1998). Anti-GBM glomerulonephritis in mice lacking nitric oxide synthase type 2. Kidney Int. 53:932-936. DOI.
  • Waddington SN; Tam FW; Cook HT; Cattell V. (Mar 1998). Arginase activity is modulated by IL-4 and HOArg in nephritic glomeruli and mesangial cells. Am J Physiol. 274:F473-F480.
  • Powles AV; Hardman CM; Porter WM; Cook T; Hulme B; Fry L. (Mar 1998). Renal function after 10 years' treatment with cyclosporin for psoriasis. Br J Dermatol. 138:443-449.
  • Mosley K; Wembridge DE; Cattell V; Cook HT. (Mar 1998). Heme oxygenase is induced in nephrotoxic nephritis and hemin, a stimulator of heme oxygenase synthesis, ameliorates disease. Kidney Int. 53:672-678. DOI.
  • Taylor GM; Cook HT. (1998). A practical protocol for the demonstration of NOS using in-situ hybridization. Methods Mol Biol. 100:191-204.
  • Douar AM; Adebakin S; Themis M; Pavirani A; Cook T; Coutelle C. (Sep 1997). Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus. Gene Ther. 4:883-890. DOI.
  • Chambers MA; Marshall BG; Wangoo A; Bune A; Cook HT; Shaw RJ; Young DB. (15 Feb 1997). Differential responses to challenge with live and dead Mycobacterium bovis Bacillus Calmette-Guérin. J Immunol. 158:1742-1748.
  • Wangoo A; Laban C; Cook HT; Glenville B; Shaw RJ. (Feb 1997). Interleukin-10- and corticosteroid-induced reduction in type I procollagen in a human ex vivo scar culture. Int J Exp Pathol. 78:33-41.
  • Ball S; Cook T; Hulme B; Palmer A; Taube D. (Jan 1997). The diagnosis and racial origin of 394 patients undergoing renal biopsy: an association between Indian race and interstitial nephritis. Nephrol Dial Transplant. 12:71-77.
  • Marshall BG; Wangoo A; Cook HT; Shaw RJ. (Dec 1996). Increased inflammatory cytokines and new collagen formation in cutaneous tuberculosis and sarcoidosis. Thorax. 51:1253-1261.
  • Wangoo A; Martin N; Cook HT; Glenville B; Shaw RJ. (Aug 1996). Effect of injection of triamcinolone on type 1 procollagen and fibronectin in scar tissue. Br J Surg. 83:1136-1137.
  • Cairns T; Lee J; Goldberg LC; Hakim N; Cook T; Rydberg L; Samuelsson B; Taube D. (Apr 1996). Thomsen-Friedenreich and PK antigens in pig-to-human xenotransplantation. Transplant Proc. 28:795-796.
  • Waddington S; Cook HT; Reaveley D; Jansen A; Cattell V. (Apr 1996). L-arginine depletion inhibits glomerular nitric oxide synthesis and exacerbates rat nephrotoxic nephritis. Kidney Int. 49:1090-1096.
  • Bune AJ; Brand MP; Heales SJ; Shergill JK; Cammack R; Cook HT. (7 Mar 1996). Inhibition of tetrahydrobiopterin synthesis reduces in vivo nitric oxide production in experimental endotoxic shock. Biochem Biophys Res Commun. 220:13-19. DOI.
  • Cairns T; Lee J; Goldberg L; Cook T; Simpson P; Spackman D; Palmer A; Taube D. (15 Dec 1995). Inhibition of the pig to human xenograft reaction, using soluble Gal alpha 1-3Gal and Gal alpha 1-3Gal beta 1-4GlcNAc. Transplantation. 60:1202-1207.
  • Thomas DM; Wilkins MJ; Witana JS; Cook T; Jefferis AF; Walsh-Waring GP. (Nov 1995). Giant cell reparative granuloma of the cricoid cartilage. J Laryngol Otol. 109:1120-1123.
  • Cattell V; Cook T. (Jul 1995). The nitric oxide pathway in glomerulonephritis. Curr Opin Nephrol Hypertens. 4:359-364.
  • Bune AJ; Shergill JK; Cammack R; Cook HT. (12 Jun 1995). L-arginine depletion by arginase reduces nitric oxide production in endotoxic shock: an electron paramagnetic resonance study. FEBS Lett. 366:127-130.
  • Wangoo A; Cook HT; Taylor GM; Shaw RJ. (Apr 1995). Enhanced expression of type 1 procollagen and transforming growth factor-beta in tuberculin induced delayed type hypersensitivity. J Clin Pathol. 48:339-345.
  • Goldberg L; Lee J; Cairns T; Cook T; Lin CK; Palmer A; Simpson P; Taube D. (Feb 1995). Inhibition of the human antipig xenograft reaction with soluble oligosaccharides. Transplant Proc. 27:249-250.
  • Riaz Y; Cook HT; Wangoo A; Glenville B; Shaw RJ. (Oct 1994). Type 1 procollagen as a marker of severity of scarring after sternotomy: effects of topical corticosteroids. J Clin Pathol. 47:892-899.
  • Cook HT; Jansen A; Lewis S; Largen P; O'Donnell M; Reaveley D; Cattell V. (Oct 1994). Arginine metabolism in experimental glomerulonephritis: interaction between nitric oxide synthase and arginase. Am J Physiol. 267:F646-F653.
  • Cook HT; Bune AJ; Jansen AS; Taylor GM; Loi RK; Cattell V. (Aug 1994). Cellular localization of inducible nitric oxide synthase in experimental endotoxic shock in the rat. Clin Sci (Lond). 87:179-186.
  • Cook HT; Ebrahim H; Jansen AS; Foster GR; Largen P; Cattell V. (Aug 1994). Expression of the gene for inducible nitric oxide synthase in experimental glomerulonephritis in the rat. Clin Exp Immunol. 97:315-320.
  • Cook HT; Avey C; Taylor GM. (Jun 1994). Interleukin-1 beta gene expression in experimental glomerulonephritis in the rat: an in-situ hybridization study. Int J Exp Pathol. 75:157-163.
  • Jansen A; Cook T; Taylor GM; Largen P; Riveros-Moreno V; Moncada S; Cattell V. (Apr 1994). Induction of nitric oxide synthase in rat immune complex glomerulonephritis. Kidney Int. 45:1215-1219.
  • Goldberg LC; Cook T; Taube D. (1994). Pretreatment of renal transplants with anti-CD45 antibodies: optimization of perfusion technique. Transpl Immunol. 2:27-34.
  • Thom M; Palmer A; Cattell V; Cook T. (1994). Proliferating cell nuclear antigen (PCNA) as a diagnostic marker of acute cellular rejection in routinely processed biopsies of renal allografts. Nephrol Dial Transplant. 9:153-155.
  • Toynton SC; Wilkins MJ; Cook HT; Stafford ND. (Jan 1994). True malignant mixed tumour of a minor salivary gland. J Laryngol Otol. 108:76-79.
  • Goldberg LC; Cook HT; Welsh KI; Hall L; Thick MG; Taube D. (Feb 1993). Optimizing kidney perfusion with anti-CD45 monoclonal antibody. Transplant Proc. 25:1056-1057.
  • Powles AV; Cook T; Hulme B; Baker BS; Lewis HM; Thomas E; Valdimarsson H; Fry L. (Feb 1993). Renal function and biopsy findings after 5 years' treatment with low-dose cyclosporin for psoriasis. Br J Dermatol. 128:159-165.
  • Jansen A; Lewis S; Cattell V; Cook HT. (Nov 1992). Arginase is a major pathway of L-arginine metabolism in nephritic glomeruli. Kidney Int. 42:1107-1112.
  • Sever R; Cook T; Cattell V. (Nov 1992). Urinary excretion of nitrite and nitrate in experimental glomerulonephritis reflects systemic immune activation and not glomerular synthesis. Clin Exp Immunol. 90:326-329.
  • Coker RJ; Bignardi G; Horner P; Savage M; Cook T; Tomlinson D; Weber J. (Sep 1992). Nocardia infection in AIDS: a clinical and microbiological challenge. J Clin Pathol. 45:821-822.
  • Cattell V; Largen P; de Heer E; Cook T. (Nov 1991). Glomeruli synthesize nitrite in active Heymann nephritis; the source is infiltrating macrophages. Kidney Int. 40:847-851.
  • Cook HT; Sullivan R. (Nov 1991). Glomerular nitrite synthesis in in situ immune complex glomerulonephritis in the rat. Am J Pathol. 139:1047-1052.
  • Cattell V; Cook T; Moncada S. (Dec 1990). Glomeruli synthesize nitrite in experimental nephrotoxic nephritis. Kidney Int. 38:1056-1060.
  • Cattell V; Smith J; Cook HT. (Feb 1990). Prostaglandin E1 suppresses macrophage infiltration and ameliorates injury in an experimental model of macrophage-dependent glomerulonephritis. Clin Exp Immunol. 79:260-265.
  • Diggory P; Jacyna MR; Booth JC; Cook HT; Thomas HC. (Oct 1989). Gallbladder cancer presenting with Trousseau's sign in a 31-year-old man with occupational exposure to aromatic hydrocarbons. J R Soc Med. 82:631-632.
  • Taylor M; Cook T; Pearson C; Risdon RA; Peart S. (Sep 1989). Renin messenger RNA localization in congenital mesoblastic nephroma using in situ hybridization. J Hypertens. 7:733-740.
  • Cook HT; Smith J; Salmon JA; Cattell V. (Feb 1989). Functional characteristics of macrophages in glomerulonephritis in the rat. O2- generation, MHC class II expression, and eicosanoid synthesis. Am J Pathol. 134:431-437.
  • Cook HT; Taylor GM; Malone P; Risdon RA. (Nov 1988). Renin in mesoblastic nephroma: an immunohistochemical study. Hum Pathol. 19:1347-1351.
  • Taylor GM; Cook HT; Hanson C; Peart WS; Zondek T; Zondek LH. (Oct 1988). Renin in human fetal lung--a biochemical and immunohistochemical study. J Hypertens. 6:845-851.
  • Cook HT; Stafford ND. (Sep 1988). Angiolymphoid hyperplasia with eosinophilia involving the lacrimal gland: case report. Br J Ophthalmol. 72:710-712.
  • Kitchen VS; Cook T; Doble A; Harris JR. (Aug 1988). Gummatous penile ulceration and generalised lymphadenopathy in homosexual man: case report. Genitourin Med. 64:276-279.
  • Taylor GM; Cook HT; Sheffield EA; Hanson C; Peart WS. (Mar 1988). Renin in blood vessels in human pulmonary tumors. An immunohistochemical and biochemical study. Am J Pathol. 130:543-551.
  • Cook HT; Boylston AW. (Mar 1988). Plasmacytoma of the ovary. Gynecol Oncol. 29:378-381.
  • Francis ND; Goldin RD; Forster SM; Cook HT; Coleman DV; Shaw R; Pinching AJ; Boylston AW. (Nov 1987). Diagnosis of lung disease in acquired immune deficiency syndrome: biopsy or cytology and implications for management. J Clin Pathol. 40:1269-1273.
  • Bune AJ; Cook HT. (Jan 1996). Inhibition of tetrahydrobiopterin synthesis reduces nitric oxide production by isolated glomeruli in immune complex glomerulonephritis. Exp Nephrol. 4:43-47.
  • Schneider H; Adebakin S; Themis M; Cook T; Douar AM; Pavirani A; Coutelle C. (Nov 1999). Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B. J Gene Med. 1:424-432. DOI.
  • Mosley K; Waddington SN; Ebrahim H; Cook T; Cattell V. (Jan 1999). Inducible nitric oxide synthase induction in Thy 1 glomerulonephritis is complement and reactive oxygen species dependent. Exp Nephrol. 7:26-34.
  • David AL; Peebles DM; Gregory L; Themis M; Cook T; Coutelle C; Rodeck CH. (Sep 2003). Percutaneous ultrasound-guided injection of the trachea in fetal sheep: a novel technique to target the fetal airways. Fetal Diagn Ther. 18:385-390. DOI.

Chapters in books

  • Cook HT; Pusey CD. Pathology of vascular disease. 3-21. (2001).
  • Coutelle C; Themis M; Schneider H; Cook HT. Fetal somatic gene therapy - a preventive approach to the treatment of genetic disease: the case for. 99-114. (2001).

Conferences

  • Carlucci F; Cortes-Hernandez J; Fossati-Jimack LM; Bygrave AE; Cook TH; Vyse TJ; Botto M. Genetic contribution of 129 chromosome 1 intervals to autoimmunity in C57BL/6 mice. BSR Annual Meeting/BHPR Spring Meeting. 45:I4-I4. (Apr 2006).
  • Fossati-Jimack L; Carlucci F; Heidari Y; Cook H; Botto M. Murine lupus susceptibility locus Sle16: autoantibody suppression by an epistatic effect of a chromosome 3 locus. Annual Congress of the British-Society-of-Immunology, 17 Nov 2008 - 21 Nov 2008. 125:35-35. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2008). Author weblink.
  • Ling GS; Fossati-Jimack L; Szajna M; Tahir S; Cook HT; Scott D; Simpson E; Botto M. Intranasal tolerance induction is maintained in mice lacking CD11b but through different mechanisms. Annual Congress of the British-Society-for-Immunology, 5 Dec 2011 - 8 Dec 2011. 135:196-196. WILEY-BLACKWELL (1 Dec 2011).
  • Vernon KA; de Jorge EG; Rose KL; Hall AE; Rigby E; Hangartner R; Cook HT; Koziell A; et alPickering MC. Complement Factor H-related protein 5 deficiency is a risk factor for chronic renal disease following acute post-streptococcal glomerulonephritis. 13th European Meeting on Complement in Human Disease, 21 Aug 2011 - 24 Aug 2011. 48:1728-1728. PERGAMON-ELSEVIER SCIENCE LTD (1 Aug 2011). Author weblink DOI.
  • Lawrence C; Willicombe M; Brookes P; Santos-Nunez E; Bajaj R; Cook T; Roufosse C; Taube D; et alWarrens AN. Preformed Anti-HLA -A, -B and -DR but Not -DQ Complement-Activating Low-Level Donor- Specific Antibodies Predict Early Antibody- Mediated Rejection in Renal Allografts. American Transplant Congress, 2011. 11:471-472. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Willicombe M; Galliford J; Roufosse C; Brookes P; Cook HT; Cairns T; Taube D. Acute Cellular Rejection with a Humoral Component Is Associated with Increased Risk of Subsequent Antibody Mediated Rejection, Transplant Glomerulopathy and Allograft Loss. American Transplant Congress, 2011. 11:448-448. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Galliford J; Roufosse C; Chan K; Filiopoulos V; Willicombe M; Shiu K; Dorling A; McLean A; et alCook HT; Taube D. Lack of Effective Therapy for Transplant Glomerulopathy. American Transplant Congress, 2011. 11:401-401. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Galliford J; Lawrence C; Willicombe M; Chan K; Roufosse C; McLean A; Cairns T; Cook HT; et alTaube D. Reversal of Refractory Acute Antibody Mediated Rejection with Eculizumab. American Transplant Congress, 2011. 11:352-352. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Willicombe M; Brookes P; Roufosse C; Galliford J; Cook HT; Cairns T; McLean A; Taube D. Detection of Donor Specific Antibodies Predicts Antibody Mediated Rejection and Transplant Glomerulopathy. American Transplant Congress, 2011. 11:295-296. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Willicombe M; Santos-Nunez E; Brookes P; Roufosse C; Cook HT; Galliford J; Taube D. De Novo HLA-DQ Donor Specific Antibodies Are Associated with a Higher Risk of Rejection and Transplant Glomerulopathy. American Transplant Congress, 2011. 11:203-203. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Shiu KY; Mesa IR; Perucha E; Sagoo P; Cook HT; Roufosse C; Brookes P; Clarke H; et alWillicombe M; Lechler RI; Hernandez-Fuentes M; Dorling A. Alloreactive IFN gamma-Producing CD4+T-Cells from Renal Transplant Recipients with Chronic Antibody-Mediated Rejection (CAMR) Are B-Cell Dependent In Vitro. American Transplant Congress, 2011. 11:195-195. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Shiu KY; Mesa IR; Perucha E; Sagoo P; Jimenez-Vera E; Cook HT; Brookes P; Galliford J; et alTaube D; Lechler RI; Hernandez-Fuentes M; Dorling A. CD4+T Cell IFN gamma-Production Strongly Predicts Future Graft Dysfunction in Patients with Chronic Antibody-Mediated Rejection (CAMR) Diagnosed on Protocol Biopsy. American Transplant Congress, 2011. 11:194-194. WILEY-BLACKWELL (1 Apr 2011). Author weblink.
  • Pepper RJ; Tarzi R; Wang H-H; Pusey CD; Cook HT; Salama AD. Critical role for calprotectin in ANCA-AAV and GN. 15th International Vasculitis/ANCA Workshop, 15 May 2011 - 18 May 2011. 164:129-129. WILEY-BLACKWELL (1 May 2011). Author weblink.
  • Santos-Nunez E; Willicombe M; Brookes P; Galliford J; Mclean A; Roufosse C; Cook T; Cairns T; et alTaube D. De novo donor specific antibodies are associated with a high incidence of antibody mediated rejection, transplant glomerulopathy and graft loss. 25th Conference on European Immunogenetics and Histocompatibility, 4 May 2011 - 7 May 2011. 77:453-454. WILEY-BLACKWELL (1 May 2011). Author weblink.
  • de Jorge EG; Cook HT; Botto M; Pickering MC. Insights into the role of complement dysregulation in atypical haemolytic uremic syndrome. 12th European Meeting on Complement in Human Disease, 5 Sep 2009 - 8 Sep 2009. 46:2851-2851. PERGAMON-ELSEVIER SCIENCE LTD (1 Sep 2009). DOI.
  • de Jorge EG; Gale DP; Cook HT; Martinez-Barricarte R; Hadjisavvas A; Pusey CD; Palmer A; Fremeaux-Bacchi V; et alRodriguez de Cordoba S; Maxwell PH; Pickering MC. A mutant complement factor H-related 5 protein is associated with familial C3 glomerulonephritis. 12th European Meeting on Complement in Human Disease, 5 Sep 2009 - 8 Sep 2009. 46:2822-2822. PERGAMON-ELSEVIER SCIENCE LTD (1 Sep 2009). Author weblink DOI.
  • Chan K; Galliford J; Charif R; Cook T; Chusney G; Goodall D; Roufosse C; McLean A; et alTaube D. Tacrolimus Weaning Is Not Necessary after Alemtuzumab Induction in Live Related Renal Transplantation. 9th Joint Meeting of the American-Society-of-Transplant-Surgeon/American-Society-of-Transplantation, 30 May 2009 - 3 Jun 2009. 9:675-675. WILEY-BLACKWELL PUBLISHING, INC (1 Jan 2009). Author weblink.
  • Galliford J; Chan K; Willicombe M; Roufosse C; Hakim N; Papalois V; Warrens A; McLean A; et alCook T; Taube D. Renal Allograft Rejection after Alemtuzumab Induction and Tacrolimus Monotherapy. 9th Joint Meeting of the American-Society-of-Transplant-Surgeon/American-Society-of-Transplantation, 30 May 2009 - 3 Jun 2009. 9:620-621. WILEY-BLACKWELL PUBLISHING, INC (1 Jan 2009). Author weblink.
  • Galliford J; Chan K; Charif R; Cook T; Roufosse C; Kumar N; Loucaidou M; McLean A; et alHakim N; Papalois V; Taube D. ABO Incompatible Live Donor Transplantation with Alemtuzumab Induction, Tacrolimus Monotherapy and a Steroid Sparing Protocol. 9th Joint Meeting of the American-Society-of-Transplant-Surgeon/American-Society-of-Transplantation, 30 May 2009 - 3 Jun 2009. 9:557-557. WILEY-BLACKWELL PUBLISHING, INC (1 Jan 2009). Author weblink.
  • Karcz M; Dorling A; Cook HT; Papalois V. An Ex-Vivo Model for Hypothermic Pulsatile Perfusion of Porcine Pancreata. 9th Joint Meeting of the American-Society-of-Transplant-Surgeon/American-Society-of-Transplantation, 30 May 2009 - 3 Jun 2009. 9:267-268. WILEY-BLACKWELL PUBLISHING, INC (1 Jan 2009). Author weblink.
  • Reynolds J; Marshall D; Shaw S; Gelinas RE; Cook HT; Pusey CD. Effect of anti-IL6 monoclonal antibody therapy in experimental autoimmune glomerulonephritis in the CD1 mouse. Annual Congress of the British-Society-of-Immunology, 17 Nov 2008 - 21 Nov 2008. 125:60-60. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2008). Author weblink.
  • Reynolds J; Tadros S; Smith J; Cook PR; Bhangal G; Salama AD; Aitman TJ; Cook HT; et alPusey CD. Genetic susceptibility to experimental autoimmune glomerulonephritis in congenic rats. Annual Congress of the British-Society-of-Immunology, 17 Nov 2008 - 21 Nov 2008. 125:36-37. WILEY-BLACKWELL PUBLISHING, INC (1 Dec 2008). Author weblink.
  • Paixao-Cavalcante D; Hanson S; Cook HT; Botto M; Pickering MC. Administration of purified mouse factor H into factor H-deficient mice removes glomerular basement membrane C3. 22nd International Complement Workshop, 28 Sep 2008 - 2 Oct 2008. 45:4127-4127. PERGAMON-ELSEVIER SCIENCE LTD (1 Oct 2008). Author weblink DOI.
  • Baruah P; Dumitriu IE; Malik T; Cook HT; Dyson J; Scott D; Simpson E; Botto M. C1q enhances IFN-gamma production by antigen specific T cells via the CD40 co-stimulatory pathway on dendritic cells. 22nd International Complement Workshop, 28 Sep 2008 - 2 Oct 2008. 45:4105-4106. PERGAMON-ELSEVIER SCIENCE LTD (1 Oct 2008). Author weblink DOI.
  • de Jorge EG; Paixao-Cavalcante D; Rose KL; Cook HT; Botto M; Pickering MC. C5 activation is required for the development of atypical haemolytic uraemic syndrome in Cfh-/-FH Delta 16-20 mice. 22nd International Complement Workshop, 28 Sep 2008 - 2 Oct 2008. 45:4100-4101. PERGAMON-ELSEVIER SCIENCE LTD (1 Oct 2008). Author weblink DOI.
  • Fang TC; Otto WR; Rao J; Jeffery R; Hunt T; Alison MR; Cook HT; Wright NA; et alPoulsom R. Haematopoietic lineage-committed bone marrow cells, but not cloned cultured mesenchymal stem cells, contribute to regeneration of renal tubular epithelium after HgCl2-induced acute tubular injury. 43rd Annual Congress of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA). 41:575-591. (Aug 2008).
  • Prodromidi E; Poulsom R; Pusey C; Cook T. Bone marrow-derived stem cells contribute to regeneration and repair of the kidney. Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, 28 Jun 2008 - 3 Jul 2008. 275:462-462. BLACKWELL PUBLISHING (1 Jun 2008). Author weblink.
  • Galliford J; Shiu K; Chan K; England M; Cook T; McLean A; Warrens A; Taube D; et alDorling A. Treatment of late antibody mediated rejection in renal transplant recipients. 8th American Transplant Congress. 8:442-443. (May 2008).
  • Galliford JW; Chan K; McLean AG; Cook HT; Charif R; Dorling A; Warrens AN; Taube D. Renal allograft rejection after Campath induction and medium dose tacrolimus monotherapy without steroids. 8th American Transplant Congress, 31 May 2008 - 4 Jun 2008. 8:580-580. BLACKWELL PUBLISHING (1 May 2008). Author weblink.
  • David AL; McIntosh J; Weisz B; Boyd M; Cook T; Wigley V; Kymalainen H; Abi-Nader K; et alRodeck CH; Peebles DM; Nathwani A. Long term perinatal gene transfer after clinically applicable delivery of prenatal gene therapy in the sheep. 5th Annual Conference of the British-Society-for-Gene-Therapy. 19:397-397. (Apr 2008).
  • David AL; Torondel B; Wigley V; Abi-Nader K; Zachary I; Martin J; Boyd M; Cook T; et alRodeck C; Peebles D. Long-term increases in vasorelaxation and blood flow to the pregnant sheep uterus following local delivery of adenovirus VEGF to uterine arteries. 55th Annual Meeting of the Society-for-Gynecologic-Investigation. 15:62A-62A. (Feb 2008).
  • David AL; McIntosh J; Nathwani A; Cook T; Boyd M; Weisz B; Wigley V; Abi-Nader K; et alRodeck C; Peebles D. Long term expression of human factor IX after ultrasound-guided fetal gene therapy in sheep. 55th Annual Meeting of the Society-for-Gynecologic-Investigation, 26 Mar 2008 - 29 Mar 2008. 15:134A-134A. SAGE PUBLICATIONS INC (1 Feb 2008). Author weblink.
  • Cook HT. Interpretation of renal biopsies in IgA nephropathy. 11th International Symposium on IgA Nephropathy. 157:44-49. (2007).
  • Paixao-Cavalcante D; Cook HT; Botto M; Pickering MC. Shigatoxin-2 does not result in thrombotic microangiopathy in heterozygous factor H-deficient mice. 11th European Meeting on Complement in Human Disease. 44:3974-3974. (Sep 2007).
  • Rose KL; Paixao-Cavalcante D; Fish J; Manderson AP; Malik T; Bygrave AE; Lin T; Sacks SH; et alWalport MJ; Cook HT; Botto M; Pickering MC. Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. 11th European Meeting on Complement in Human Disease. 44:3924-3924. (Sep 2007).
  • Themis M; Waddington S; Holder M; Buckley S; Mitrophanos K; Bigger B; Lawrence L; Cook T; et alAllaf F; Kingsman S; Coutelle C; Gregory L. Highly efficient and comprehensive gene transfer to all muscle groups necessary for the potential treatment of Duchenne/Becker muscular dystrophies following in utero delivery of a lentivirus vector in immuno-competent mice. 6th Annual Meeting of the American-Society-of-Gene-Therapy. 7:S320-S320. (May 2003).
  • Waddington SN; Buckley SMK; Cook T; Gregory L; Rahim A; Nivsarkar M; Themis M; Bernloehr C; et alNeubert WJ; Lauer UM; Coutelle C; Bitzer M. Fetal gene delivery using first and second generation Sendai virus. 6th Annual Meeting of the American-Society-of-Gene-Therapy. 7:S4-S4. (May 2003).
  • Tarzi RM; Cook HT; Jackson I; Pusey CD; Lord GM. Leptin deficient mice are protected from nephrotoxic nephritis. 36th Annual Meeting of the American-Society-of-Nephrology. 14:175A-175A. (Nov 2003).
  • Waddington SN; Nivsarkar M; Mistry A; Buckley SMK; Kemball-Cook G; Mosley KL; Mitrophanous K; Radcliffe P; et alHolder M; Brittan M; Georgiadis T; Al-Allaf F; Bigger B; Gregory L; Cook HT; Ali RR; Thrasher A; Tuddenham EGD; Themis M; Coutelle C. Permanent phenotypic correction of Haemophilia B in immunocompetent mice by prenatal gene therapy. 1st Annual Conference of the British-Society-for-Gene-Therapy. 6:S17-S17. (Sep 2004).
  • David A; Weisz B; Peebles D; Roubliova X; Perocheau D; Themis M; Cook T; Coutelle C; et alDeprest J; Rodeck C. Ultrasound guided placement of an occlusive balloon in the trachea of fetal sheep. 25th Annual Meeting of the Society-for-Maternal-Fetal-Medicine. 191:S166-S166. (Dec 2004).
  • Weisz B; David A; Peebles D; Gregory L; Perocheau D; Waddington S; Themis M; Cook T; et alCoutelle C; Rodeck C. Targeting the fetal respiratory muscles for prenatal gene therapy for Duchenne muscular dystrophy. 25th Annual Meeting of the Society-for-Maternal-Fetal-Medicine. 191:S22-S22. (Dec 2004).
  • Pickering MC; Turnberg DA; Warren J; Carlucci F; Cook HT; Botto M. The role of the alternative pathway in accelerated serum nephrotoxic nephritis in C57BL/6 mice. 10th Meeting on Complement in Human Disease. 43:170-170. (Jan 2006).
  • Prodromidi EI; Turnberg D; Roufosse CA; Jeffery R; Pusey CD; Poulsom R; Cook HT. Bone marrow-derived cells contribute to a small extent to regeneration of renal parenchyma after injury. 3rd Joint Meeting of the British Division of the International-Academy-of-Pahtology/Meeting of the Pathological-Society-of-Great-Britian-and-Ireland. 207:2-2. (Oct 2005).
  • Roufosse C; Bou-Gharios G; Prodromidi E; Jeffery R; Hunt T; Alexakis C; Khan S; Cook T; et alPoulsom R. Bone marrow-derived cells participate in renal regeneration but make a trivial contribution to collagen I synthesis in a murine model of kidney fibrosis. Spring Meeting of the British-Society-for-Matrix-Biology. 86:A78-A79. (Dec 2005).
  • Prodromidi EI; Poulsom R; Jeffery R; Roufosse CA; Hunt T; Pusey CD; Cook HT. Bone marrow contributes to podocyte regeneration and amelioration of renal disease in Alport's syndrome. 190th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland. 210:60-60. (Sep 2006).
  • Pickering MC; Rose KL; Carlucci F; Howard J; Cook HT; Botto M. Increased susceptibility of heterozygous factor H deficient mice to accelerated serum nephrotoxic nephritis. 21st International Complement Workshop. 44:228-228. (Jan 2007).
  • Fossati-Jimack L; Cortes-Hernandez J; Norsworthy P; Cook HT; Botto M. C1q can alter the levels of IgM autoantibody production in anti-DNA transgenic models. 21st International Complement Workshop. 44:171-171. (Jan 2007).
  • Yen TH; Alison MR; Cook HT; Jeffery R; Otto WR; Wright NA; Poulsom R. The cellular origin and proliferative status of regenerating renal parenchyma after mercuric chloride damage and erythropoietin treatment. 189th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland. 40:143-156. (Apr 2007).
  • Galliford J; Cook T; Brookes P; Chan K; Taube D; Dorling A. Reversal of refractory c4d chronic allograft nephropathy with ritximab. Annual American Transplant Congress. 7:526-526. (May 2007).
  • Pickering MC; de Jorge EG; Rose KL; Moss J; Cook HT; de Cordoba SR; Botto M. Spontaneous haemolytic uraemic syndrome (HUS) in factor H-deficient mice transgenic for murine factor H protein lacking the five C-terminal domains (FH Delta 16-20). 21st International Complement Workshop, 22 Oct 2006 - 26 Oct 2006. 44:227-228. PERGAMON-ELSEVIER SCIENCE LTD (1 Jan 2007). Author weblink DOI.
  • Fang T-C; Poulsom R; Alison MR; Cook HT; Otto WR; Rao J; Jeffery R; Hunt T; et alWright NA. Haematopoietic lineage-committed marrow cells, but not cloned cultured mesenchymal stem cells, contribute to regeneration after acute tubular necrosis. 43rd ERA-EDTA Congress, 15 Jul 2006 - 18 Jul 2006. 21:319-320. OXFORD UNIV PRESS (1 Jul 2006). Author weblink.
  • Stangou M; Bhangal G; Lai P-C; Smith J; Keith J; Boyle J; Pusey C; Cook T; et alTam F. Interleukin-11 suppressed fibrotic processes in nephrotoxic nephritis in Wistar Kyoto Rats. 43rd ERA-EDTA Congress, 15 Jul 2006 - 18 Jul 2006. 21:36-37. OXFORD UNIV PRESS (1 Jul 2006). Author weblink.
  • Yen TH; Alison MR; Cook HT; Wright NA; Poulsom R. Renal regeneration following acute tubular necrosis utilises cells of bone marrow origin, but is unaffected by EPO. 189th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, 4 Jan 2006 - 6 Jan 2006. 208:31A-31A. JOHN WILEY & SONS LTD (1 Mar 2006). Author weblink.
  • Roufosse C; Alexakis C; Bou-Gharios G; Otto W; Prodromidi E; Alter J; Jeffery R; Cook HT; et alPoulsom R. Bone marrow-derived haematopoietic and mesenchymal stem cells colonise kidney but fail to produce collagen I in renal fibrosis. 189th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, 4 Jan 2006 - 6 Jan 2006. 208:17A-17A. JOHN WILEY & SONS LTD (1 Mar 2006). Author weblink.
  • Turnberg D; Botto M; Warren J; Zhou WD; Sacks SH; Morgan P; Walport MJ; Cook T. CD59a deficiency exacerbates adriamycin nephropathy and ischaemia-reperfusion injury in mice. 36th Annual Meeting of the American-Society-of-Nephrology, 12 Nov 2003 - 17 Nov 2003. 14:163A-163A. LIPPINCOTT WILLIAMS & WILKINS (1 Nov 2003). Author weblink.
  • Themis M; Gregory LG; Waddington SN; Holder MV; Mitrophanous KA; Buckley SMK; Bigger BW; Ellard FE; et alWalmsley LE; Radcliff P; Mazarakis N; Azzouz M; Lawrence L; Cook T; Allaf FA; Kingsman S; Coutelle C. The fetal approach: A novel therapy for the treatment of musculo-skeletal disease. 7th Annual Meeting of the American-Society-of-Gene-Therapy, 2 Jun 2004 - 6 Jun 2004. 9:S91-S91. ACADEMIC PRESS INC ELSEVIER SCIENCE (1 May 2004). Author weblink.
  • Fang TC; Poulsom R; Cook HT; Alison MR; Wright NA. Tubular regeneration after folie acid-induced acute renal failure involves proliferation of bone marrow-derived epithelium. 186th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland/Dutch-Pathological-Society, 6 Jul 2004 - 9 Jul 2004. 204:11A-11A. JOHN WILEY & SONS LTD (1 Sep 2004). Author weblink.
  • Fang TC; Alison MR; Cook HT; Jeffery R; Wright NA; Poulsom R. Proliferation of bone marrow-derived cells contributes to regeneration after folic acid-induced acute tubular injury. 186th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland/Dutch-Pathological-Society, 6 Jul 2004 - 9 Jul 2004. 16:1723-1732. LIPPINCOTT WILLIAMS & WILKINS (1 Jun 2005). DOI.
  • Roufosse CA; Bou-Gharios G; Prodromidi E; Jeffery R; Hunt T; Alexakis C; Khan S; Cook T; et alPoulsom R. Bone marrow-derived cells and mesenchymal-epithelial transition in kidney fibrosis. 3rd Joint Meeting of the British Division of the International-Academy-of-Pahtology/Meeting of the Pathological-Society-of-Great-Britian-and-Ireland, 5 Jul 2005 - 8 Jul 2005. 207:3-3. JOHN WILEY & SONS LTD (1 Oct 2005). Author weblink.
  • Trendelenburg M; Hernandes-Cortes J; Walport SIMJ; Cook HT; Fossati-Jimack L; Botto M. The role of complement in cryoglobulin-induced immune complex glomerulonephritis. 9th European Meeting on Complement in Human Disease, 6 Sep 2003 - 9 Sep 2003. 40:192-192. PERGAMON-ELSEVIER SCIENCE LTD (1 Sep 2003). Author weblink.
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