Publications
Journals
- Thorley AJ; Grandolfo D; Lim E; Goldstraw P; Young A; Tetley TD. (15 Jul 2011). Innate immune responses to bacterial ligands in the peripheral human lung - role of alveolar epithelial TLR expression and signalling. PLoS One. 6(7):.
- Maynard RL; Donaldson K; Tetley TD. (31 Jan 2012). Type 1 pulmonary epithelial cells: a new compartment involved in the slow phase of particle clearance from alveoli. Nanotoxicology. DOI.
- Thorley AJ; Grandolfo D; Lim E; Goldstraw P; Young A; Tetley TD. (2011). Innate immune responses to bacterial ligands in the peripheral human lung--role of alveolar epithelial TLR expression and signalling. PLoS One. 6:e21827. DOI.
- Ruenraroengsak P; Novak P; Berhanu D; Thorley AJ; Valsami-Jones E; Gorelik J; Korchev YE; Tetley TD. (Feb 2012). Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles. Nanotoxicology. 6:94-108. DOI.
- Bolasco G; Tracey-White DC; Tolmachova T; Thorley AJ; Tetley TD; Seabra MC; Hume AN. (Mar 2011). Loss of Rab27 function results in abnormal lung epithelium structure in mice. Am J Physiol Cell Physiol. 300:C466-C476. DOI.
- Swain RJ; Kemp SJ; Goldstraw P; Tetley TD; Stevens MM. (21 Apr 2010). Assessment of cell line models of primary human cells by Raman spectral phenotyping. Biophys J. 98:1703-1711. DOI.
- Maher TM; Evans IC; Bottoms SE; Mercer PF; Thorley AJ; Nicholson AG; Laurent GJ; Tetley TD; et alChambers RC; McAnulty RJ. (1 Jul 2010). Diminished prostaglandin E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med. 182:73-82. DOI.
- Tsoumakidou M; Kemp SJ; Thorley AJ; Zhu J; Dewar A; Jeffery PK; Tetley TD. (1 Jun 2009). Expression of blood dendritic cell antigens (BDCAs) by CD1a(+) human pulmonary cells. RESPIRATORY MEDICINE. 103:935-938. Author weblink DOI.
- van den Bogaard EHJ; Dailey LA; Thorley AJ; Tetley TD; Forbes B. (1 May 2009). Inflammatory Response and Barrier Properties of a New Alveolar Type 1-Like Cell Line (TT1). PHARMACEUTICAL RESEARCH. 26:1172-1180. Author weblink DOI.
- Mercer PF; Johns RH; Scotton CJ; Krupiczojc MA; Königshoff M; Howell DC; McAnulty RJ; Das A; et alThorley AJ; Tetley TD; Eickelberg O; Chambers RC. (1 Mar 2009). Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Am J Respir Crit Care Med. 179:414-425. DOI.
- BéruBé K; Aufderheide M; Breheny D; Clothier R; Combes R; Duffin R; Forbes B; Gaça M; et alGray A; Hall I; Kelly M; Lethem M; Liebsch M; Merolla L; Morin JP; Seagrave J; Swartz MA; Tetley TD; Umachandran M. (Feb 2009). In vitro models of inhalation toxicity and disease. The report of a FRAME workshop. Altern Lab Anim. 37:89-141.
- Medford ARL; Douglas SK; Godinho SIH; Uppington KM; Armstrong L; Gillespie KM; van Zyl B; Tetley TD; et alIbrahim NBN; Millar AB. (9 Apr 2009). Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury. RESPIRATORY RESEARCH. 10. Author weblink DOI.
- Swain RJ; Kemp SJ; Goldstraw P; Tetley TD; Stevens MM. (15 Dec 2008). Spectral Monitoring of Surfactant Clearance during Alveolar Epithelial Type II Cell Differentiation. BIOPHYSICAL JOURNAL. 95:5978-5987. Author weblink DOI.
- Kemp SJ; Thorley AJ; Gorelik J; Seckl MJ; O'Hare MJ; Arcaro A; Korchev Y; Goldstraw P; et alTetley TD. (1 Nov 2008). Immortalization of Human Alveolar Epithelial Cells to Investigate Nanoparticle Uptake. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 39:591-597. DOI.
- Tetley TD. (Jun 2007). Health effects of nanomaterials. Biochem Soc Trans. 35:527-531. DOI.
- Arcaro A; Aubert M; Espinosa del Hierro ME; Khanzada UK; Angelidou S; Tetley TD; Bittermann AG; Frame MC; et alSeckl MJ. (May 2007). Critical role for lipid raft-associated Src kinases in activation of PI3K-Akt signalling. Cell Signal. 19:1081-1092. DOI.
- Thorley AJ; Ford PA; Giembycz MA; Goldstraw P; Young A; Tetley TD. (1 Jan 2007). Differential regulation of cytokine release and leukocyte migration by lipopolysaccharide-stimulated primary human lung alveolar type II epithelial cells and macrophages. J Immunol. 178:463-473.
- Thorley AJ; Tetley TD. (2007). Pulmonary epithelium, cigarette smoke, and chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2:409-428.
- T D Tetley. (Dec 2005). Inflammatory cells and chronic obstructive pulmonary disease. Current Drug Targets Inflammation & Allergy. 6, 4:607-618.
- Thorley AJ; Goldstraw P; Young A; Tetley TD. (Apr 2005). Primary human alveolar type II epithelial cell CCL20 (macrophage inflammatory protein-3alpha)-induced dendritic cell migration. Am J Respir Cell Mol Biol. 32:262-267. DOI.
- Armstrong L; Medford AR; Uppington KM; Robertson J; Witherden IR; Tetley TD; Millar AB. (Aug 2004). Expression of functional toll-like receptor-2 and -4 on alveolar epithelial cells. Am J Respir Cell Mol Biol. 31:241-245. DOI.
- Pardo OE; Lesay A; Arcaro A; Lopes R; Ng BL; Warne PH; McNeish IA; Tetley TD; et alLemoine NR; Mehmet H; Seckl MJ; Downward J. (1 Aug 2004). Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells (vol 23, pg 7600, 2003). MOLECULAR AND CELLULAR BIOLOGY. 24:6887-6887. Author weblink DOI.
- Payne JP; Kemp SJ; Dewar A; Goldstraw P; Kendall M; Chen LC; Tetley TD. (May 2004). Effects of airborne World Trade Center dust on cytokine release by primary human lung cells in vitro. J Occup Environ Med. 46:420-427.
- Witherden IR; Vanden Bon EJ; Goldstraw P; Ratcliffe C; Pastorino U; Tetley TD. (Apr 2004). Primary human alveolar type II epithelial cell chemokine release: effects of cigarette smoke and neutrophil elastase. Am J Respir Cell Mol Biol. 30:500-509. DOI.
- Maynard RM; Tetley TD. (Mar 2004). Bioterrorism: the lung under attack. Thorax. 59:188-189.
- Kendall M; Guntern J; Lockyer NP; Jones FH; Hutton BM; Lippmann M; Tetley TD. (2004). Urban PM2.5 surface chemistry and interactions with bronchoalveolar lavage fluid. Inhal Toxicol. 16 Suppl 1:115-129. DOI.
- Lucattelli M; Cavarra E; de Santi MM; Tetley TD; Martorana PA; Lungarella G. (Nov 2003). Collagen phagocytosis by lung alveolar macrophages in animal models of emphysema. Eur Respir J. 22:728-734.
- Pardo OE; Lesay A; Arcaro A; Lopes R; Ng BL; Warne PH; McNeish IA; Tetley TD; et alLemoine NR; Mehmet H; Seckl MJ; Downward J. (Nov 2003). Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells. Mol Cell Biol. 23:7600-7610.
- Arcaro A; Khanzada UK; Vanhaesebroeck B; Tetley TD; Waterfield MD; Seckl MJ. (1 Oct 2002). Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation. EMBO J. 21:5097-5108.
- Kamal AM; Corrigan CJ; Tetley TD; Alaghband-Zadeh J; Smith SF. (Sep 2002). Effect of fluticasone on the elastase:antielastase profile of the normal lung. Eur J Clin Invest. 32:713-719.
- Tetley TD. (May 2002). Macrophages and the pathogenesis of COPD. Chest. 121:156S-159S.
- Kendall M; Tetley TD; Wigzell E; Hutton B; Nieuwenhuijsen M; Luckham P. (Jan 2002). Lung lining liquid modifies PM(2.5) in favor of particle aggregation: a protective mechanism. Am J Physiol Lung Cell Mol Physiol. 282:L109-L114.
- Pardo OE; Arcaro A; Salerno G; Tetley TD; Valovka T; Gout I; Seckl MJ. (15 Nov 2001). Novel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cells. Oncogene. 20:7658-7667. DOI.
- Bingle L; Tetley TD; Bingle CD. (Jul 2001). Cytokine-mediated induction of the human elafin gene in pulmonary epithelial cells is regulated by nuclear factor-kappaB. Am J Respir Cell Mol Biol. 25:84-91.
- Kendall M; Hutton BM; Tetley TD; Nieuwenhuijsen MJ; Wigzell E; Jones FH. (2 Jul 2001). Investigation of fine atmospheric particle surfaces and lung lining fluid interactions using XPS. APPLIED SURFACE SCIENCE. 178:27-36. Author weblink DOI.
- Mistry R; Snashall PD; Totty N; Guz A; Tetley TD. (1 Aug 1999). Purification and N-terminal amino acid sequence of sheep neutrophil cathepsin G and elastase. Arch Biochem Biophys. 368:7-13. DOI.
- Hall SE; Lim S; Witherden IR; Tetley TD; Barnes PJ; Kamal AM; Smith SF. (Jan 1999). Lung type II cell and macrophage annexin I release: differential effects of two glucocorticoids. Am J Physiol. 276:L114-L121.
- Smith SF; Benjamin A; Dewar A; Sheppard M; Fox B; Smith T; Guz A; Tetley TD. (1995). Effect of dexamethasone on carrageenin-induced inflammation in the lung. Mediators Inflamm. 4:273-281. DOI.
Chapters in books
- Tetley TD. Proteinase inhibitors: Secretory Leukoprotease Inhibitor and Elafin. In Encyclopedia of Respiratory Medicine. Laurent GJ (ed); Shapiro S (ed). Elsevier (2006).
- Tetley TD. Antiprotease therapy. In Therapeutic strategies in COPD. 233-246. Cazzola M (ed); Celli B (ed); Dahl R (ed); Rennard S (ed). Taylor & Francis, Oxford (2005).
- Tetley TD. Smoking and the Lung. In Drink, Drugs and Dependency. From science to clinical practice. 93-106. Caan W (ed); De BJ (ed). Gordon & Breach, New York; London (2002).
- Witherden IR; Tetley TD. Isolation and Culture of Human Alveolar Type II Pneumocytes. In Human Airway Inflammation: Sampling Techniques and Analytical Protocols. 137-146. Rogers DF (ed); Donnelly LE (ed). Humana Press, New Jersey (2001).
- Tetley TD. Neutrophil- and macrophage-derived proteases in chronic obstructive pulmonary disease and acute respiratory distress syndrome. In Acute Lung Injury: From Inflammation to Repair. 129-142. Bellingan G (ed); Laurent GJ (ed). IOS Press, Amsterdam (2000).
Conferences
- Berhanu D; Dybowska A; Misra SK; Stanley CJ; Ruenraroengsak P; Boccaccini AR; Tetley TD; Luoma SN; et alPlant JA; Valsami-Jones E. Characterisation of carbon nanotubes in the context of toxicity studies. Joint Environment and Human Health Programme/Annual Science Day Conference and Workshop, 24 Feb 2009 - 25 Feb 2009. 8. BIOMED CENTRAL LTD (1 Jan 2009). DOI.
- Valsami-Jones E; Berhanu D; Dybowska A; Misra S; Boccaccini AR; Tetley TD; Luoma SN; Plant JA. Nanomaterial synthesis and characterization for toxicological studies: TiO2 case study. 8th International Symposium on the Geochemistry of the Earths Surface (GES-8), 18 Aug 2008 - 22 Aug 2008. 72:515-519. MINERALOGICAL SOC (1 Feb 2008). Author weblink DOI.
- Maher TM; Bottoms SE; Mercer PF; Scotton CJ; Thorley A; Wells AU; Nicholson AG; Laurent GJ; et alTetley TD; Chambers RC; Mcanulty RJ. Differential modulation of lung fibroblast and alveolar epithelial cell apoptosis by cyclo-oxygenase (COX)-2 and prostaglandin E-2 is an important mechanism in the pathogenesis of idiopathic pulmonary fibrosis. Winter Meeting of the British-Thoracic-Society. 62:A24-A24. (Dec 2007).


