Publications

Journals

• Chuang SC; Vermeulen R; Sharabiani MTA; Sacerdote C; Fatemeh SH; Berrino F; Krogh V; Palli D; et alPanico S; Tumino R; Athersuch TJ; Vineis P. (Sep 2011). The intake of grain fibers modulates cytokine levels in blood. BIOMARKERS. 16:504-510. DOI.
• Chuang SC; Vermeulen R; Sharabiani MT; Sacerdote C; Fatemeh SH; Berrino F; Krogh V; Palli D; et alPanico S; Tumino R; Athersuch TJ; Vineis P. (Sep 2011). The intake of grain fibers modulates cytokine levels in blood. Biomarkers. 16:504-510. DOI.
• Stebbing J; Sharma A; North B; Athersuch TJ; Zebrowski A; Pchejetski D; Coombes RC; Nicholson JK; et alKeun HC. (4 Aug 2011). A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy. Ann Oncol. DOI.
• Ellis JK; Athersuch TJ; Cavill R; Radford R; Slattery C; Jennings P; McMorrow T; Ryan MP; et alEbbels TMD; Keun HC. (2011). Metabolic response to low level toxicant exposure in a novel renal tubule epithelial cell system (vol 7, pg 247, 2011). MOL BIOSYST. 7:2081-2086.
• Cavill R; Kamburov A; Ellis JK; Athersuch TJ; Blagrove MS; Herwig R; Ebbels TM; Keun HC. (Mar 2011). Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. PLoS Comput Biol. 7:e1001113. DOI.
• Keun HC; Ellis JK; Thomas LDK; Teichert F; Athersuch TJ; Svendsen C; Spurgeon DJ; Singh R; et alJarup L; Bundy JG. (Nov 2010). Metabolomics, human health and the environment: big opportunities for small molecule profiling. MUTAGENESIS. 25:637-638.
• Keun HC; Athersuch TJ. (2011). Nuclear magnetic resonance (NMR)-based metabolomics. Methods Mol Biol. 708:321-334. DOI.
• Ellis JK; Athersuch TJ; Cavill R; Radford R; Slattery C; Jennings P; McMorrow T; Ryan MP; et alEbbels TM; Keun HC. (Jan 2011). Metabolic response to low-level toxicant exposure in a novel renal tubule epithelial cell system. Mol Biosyst. 7:247-257. DOI.
• Chadeau-Hyam M; Athersuch TJ; Keun HC; De Iorio M; Ebbels TM; Jenab M; Sacerdote C; Bruce SJ; et alHolmes E; Vineis P. (Feb 2011). Meeting-in-the-middle using metabolic profiling - a strategy for the identification of intermediate biomarkers in cohort studies. Biomarkers. 16:83-88. DOI.
• Athersuch TJ; Castro-Perez J; Rodgers C; Nicholson JK; Wilson ID. (Jul 2010). UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat. Xenobiotica. 40:510-523. DOI.
• Vinken M; Doktorova T; Ellinger-Ziegelbauer H; Ahr HJ; Lock E; Carmichael P; Roggen E; van Delft J; et alKleinjans J; Castell J; Bort R; Donato T; Ryan M; Corvi R; Keun H; Ebbels T; Athersuch T; Sansone SA; Rocca-Serra P; Stierum R; Jennings P; Pfaller W; Gmuender H; Vanhaecke T; Rogiers V. (Sep 2008). The carcinoGENOMICS project: Critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays. MUTAT RES-REV MUTAT. 659:202-210. DOI.
• Ellis JK; Chan PH; Doktorova T; Athersuch TJ; Cavill R; Vanhaecke T; Rogiers V; Vinken M; et alNicholson JK; M D Ebbels T; Keun HC. (Jan 2010). Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes. J Proteome Res. 9:413-419. DOI.
• Parry JD; Pointon AV; Lutz U; Teichert F; Charlwood JK; Chan PH; Athersuch TJ; Taylor EL; et alSingh R; Luo J; Phillips KM; Vetillard A; Lyon JJ; Keun HC; Lutz WK; Gant TW. (Apr 2009). Pivotal Role for Two Electron Reduction in 2,3-Dimethoxy-1,4-naphthoquinone and 2-Methyl-1,4-naphthoquinone Metabolism and Kinetics in Vivo That Prevents Liver Redox Stress. CHEM RES TOXICOL. 22:717-725. DOI.
• Athersuch TJ; Sison RL; Kenyon ASJ; Clarkson-Jones JA; Wilson ID. (10 Sep 2008). Evaluation of the use of UPLC-TOFMS with simultaneous [C-14]-radioflow detection for drug metabolite profiling: Application to propranolol metabolites in rat urine. J PHARMACEUT BIOMED. 48:151-157. DOI.
• Pearce JTM; Athersuch TJ; Ebbels TMD; Lindon JC; Nicholson JK; Keun HC. (15 Sep 2008). Robust algorithms for automated chemical shift calibration of 1D H-1 NMR spectra of blood serum. ANAL CHEM. 80:7158-7162. DOI.
• Johnson CH; Athersuch TJ; Wilson ID; Iddon L; Meng X; Stachulski AV; Lindon JC; Nicholson JK. (1 Jul 2008). Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions. Anal Chem. 80:4886-4895. DOI.
• Keun HC; Athersuch TJ; Beckonert O; Wang Y; Saric J; Shockcor JP; Lindon JC; Wilson ID; et alHolmes E; Nicholson JK. (15 Feb 2008). Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation. Anal Chem. 80:1073-1079. DOI.
• Keun HC; Athersuch TJ. (Jul 2007). Application of metabonomics in drug development. PHARMACOGENOMICS. 8:731-741. DOI.
• Athersuch TJ; Keun H; Tang H; Nicholson JK. (13 Feb 2006). Quantitative urinalysis of the mercapturic acid conjugates of allyl formate using high-resolution NMR spectroscopy. J Pharm Biomed Anal. 40:410-416. DOI.
• Athersuch TJ; Duckett CJ; Castro-Perez J; Rodgers C; Nicholson JK; Wilson ID. (Jan 2007). Metabolism of [14C]-5-chloro-1,3-benzodioxol-4-amine in male Wistar-derived rats following intraperitoneal administration. Xenobiotica. 37:44-58. DOI.

Conferences

• Gant T; Lutz U; Parry J; Pointon A; Charlwood J; Teichert F; Athersuch T; Taylor E; et alKeun H; Lyon J; Lutz W. Two electron reduction of 2,3-dimethoxy-1,4-naphthoquinone metabolism in vivo prevents redox stress but interaction with the electron transport chain may be a mechanism of toxicity. 189:S119-S119. (13 Sep 2009). DOI.
• Athersuch TJ; Nicholson JK; Wilson ID. Isotopic enrichment enhancement in metabonomic analysis of UPLC-MS data sets. 9th International Symposium on Synthesis and Application of Isotopes and Isotopically Labelled Compounds. 50:303-307. (Apr 2007).