Dr Vithanage S Wijetunge

Publications


Journals

  • Wimalasundera RC; Wijetunge S; Thom SM; Regan L; Hughes AD. (Mar 2010). Impaired recovery of intracellular calcium and force after activation in isolated myometrial and subcutaneous resistance arteries from women with preeclampsia. J Hypertens. 28:568-574. DOI.
  • Wijetunge S; Hughes AD. (1 Sep 2007). Src family tyrosine kinases mediate contraction of rat isolated tail arteries in response to a hyposmotic stimulus. JOURNAL OF HYPERTENSION. 25:1871-1878. Author weblink DOI.
  • Kox M; Wijetunge S; Pickkers P; Hughes AD. (Mar 2007). Inhibition of Src family tyrosine kinases prevents lipopolysaccharide-induced hyporeactivity in isolated rat tail arteries. Vascul Pharmacol. 46:195-200. DOI.
  • Wijetunge S; Hughes AD. (Mar 2005). Mechanism of contraction of rat isolated tail arteries by hyposmotic solutions. J Vasc Res. 42:93-100. DOI.
  • Wijetunge S; Dolphin AC; Hughes AD. (1 Feb 2002). Tyrosine kinases act directly on the alpha1 subunit to modulate Ca(v)2.2 calcium channels. Biochem Biophys Res Commun. 290:1246-1249. DOI.
  • Wijetunge S; Dolphin AC; Hughes AD. (1 Jun 2000). Effect of tyrosine kinase inhibitors on voltage operated calcium channels expressed in COS-7 cells. JOURNAL OF PHYSIOLOGY-LONDON. 525:70P-71P.
  • Wijetunge S; Lymn JS; Hughes AD. (Apr 2000). Effects of protein tyrosine kinase inhibitors on voltage-operated calcium channel currents in vascular smooth muscle cells and pp60(c-src) kinase activity. Br J Pharmacol. 129:1347-1354. DOI.
  • Clunn GF; Wijetunge S; Hughes AD. (Dec 1999). Effect of hypercholesterolaemia on voltage-operated calcium channel currents in rabbit arterial smooth muscle cells. J Hum Hypertens. 13:849-853.
  • Wijetunge S; Lymn J; Hughes AD. (1 Oct 1999). Endogenous c-src regulates L-type calcium channels in vascular smooth muscle cells (VSMC). HYPERTENSION. 34:712-712. Author weblink.
  • Hughes AD; Wijetunge S. (Dec 1998). Role of tyrosine phosphorylation in excitation-contraction coupling in vascular smooth muscle. Acta Physiol Scand. 164:457-469.
  • Wijetunge S; Lymn JS; Hughes AD. (May 1998). Effect of inhibition of tyrosine phosphatases on voltage-operated calcium channel currents in rabbit isolated ear artery cells. Br J Pharmacol. 124:307-316. DOI.
  • Wijetunge S; Hughes AD. (1 Jan 1998). Tyrosine phosphatases regulate voltage-operated calcium channels in smooth muscle cells isolated from rabbit ear artery. JOURNAL OF VASCULAR RESEARCH. 35:12-12. Author weblink.
  • Wijetunge S; Hughes AD. (1 Mar 1997). An activator of c-Src tyrosine kinase (pY)EEI peptide increases voltage-operated calcium channel currents in vascular smooth muscle cells isolated from rabbit ear artery. BRITISH JOURNAL OF PHARMACOLOGY. 120:P83-P83. Author weblink.
  • Wijetunge S; Hughes AD. (9 Dec 1996). Activation of endogenous c-Src or a related tyrosine kinase by intracellular (pY)EEI peptide increases voltage-operated calcium channel currents in rabbit ear artery cells. FEBS Lett. 399:63-66.
  • Hughes AD; Parkinson NA; Wijetunge S. (Jan 1996). alpha2-Adrenoceptor activation increases calcium channel currents in single vascular smooth muscle cells isolated from human omental resistance arteries. J Vasc Res. 33:25-31.
  • Wijetunge S; Hughes AD. (26 Dec 1995). pp60c-src increases voltage-operated calcium channel currents in vascular smooth muscle cells. Biochem Biophys Res Commun. 217:1039-1044. DOI.
  • Wijetunge S; Hughes AD. (Jun 1995). Effect of platelet-derived growth factor on voltage-operated calcium channels in rabbit isolated ear artery cells. Br J Pharmacol. 115:534-538.
  • Hughes AD; Patel M; Wijetunge S; Clunn G; Schachter M. (Mar 1995). Comparison of effects of platelet-derived growth factor isoforms on signaling and DNA synthesis of human cultured saphenous vein cells. J Cardiovasc Pharmacol. 25:481-485.
  • Hughes AD; Wijetunge S; Parkinson NA. (Aug 1994). Isolation of single vascular smooth muscle cells from human omental resistance arteries. J Hum Hypertens. 8:615-618.
  • PARKINSON NA; WIJETUNGE S; HUGHES AD. (1 May 1994). ALPHA(2)-ADRENOCEPTOR ACTIVATION INCREASES VOLTAGE-DEPENDENT CALCIUM-CHANNEL CURRENTS IN HUMAN ARTERIAL SMOOTH-MUSCLE CELLS. BRITISH JOURNAL OF PHARMACOLOGY. 112:U111-U111. Author weblink.
  • WIJETUNGE S; HUGHES AD. (1 May 1994). THE ACTION OF ENANTIOMERS OF AMLODIPINE ON VOLTAGE-OPERATED CALCIUM CHANNELS IN VASCULAR SMOOTH-MUSCLE CELLS. BRITISH JOURNAL OF PHARMACOLOGY. 112:U208-U208. Author weblink.
  • WIJETUNGE S; HUGHES AD. (1 Jan 1994). INVOLVEMENT OF G-PROTEINS IN AGONIST-INDUCED OPENING OF RECEPTOR-OPERATED CHANNELS IN VASCULAR SMOOTH-MUSCLE CELLS. BRITISH JOURNAL OF PHARMACOLOGY. 111:P265-P265. Author weblink.
  • Hughes AD; Wijetunge S. (May 1993). The action of amlodipine on voltage-operated calcium channels in vascular smooth muscle. Br J Pharmacol. 109:120-125.
  • Wijetunge S; Aalkjaer C; Schachter M; Hughes AD. (30 Dec 1992). Tyrosine kinase inhibitors block calcium channel currents in vascular smooth muscle cells. Biochem Biophys Res Commun. 189:1620-1623.
  • WIJETUNGE S; HUGHES AD; SEVER PS. (1 Oct 1992). AMLODIPINE-INDUCED INHIBITION OF CALCIUM-CHANNEL CURRENTS IN SINGLE SMOOTH-MUSCLE CELLS ISOLATED FROM RABBIT EAR ARTERY. BRITISH JOURNAL OF PHARMACOLOGY. 107:P153-P153. Author weblink.

Conferences

  • Akunuri S; Christofi F; Wijetunge S; Hughes AD. EFFECTS OF PRORENIN-DERIVED PEPTIDES ON THE PROLIFERATION OF HUMAN CULTURED SAPHENOUS VEIN SMOOTH MUSCLE CELLS. 15th Annual Meeting of the European Council for Cadiovascular Research (ECCR), 8 Oct 2010 - 10 Oct 2010. 56:1174-1174. LIPPINCOTT WILLIAMS & WILKINS (1 Dec 2010).
  • Christofi F; Wijetunge S; Sever PS; Hughes AD. Expression and function of the tissue renin-angiotensin system in human vascular smooth muscle cells in culture. Conference on Frontiers in Cardiovascular Biology, 16 Jul 2010 - 19 Jul 2010. 87:S60-S60. OXFORD UNIV PRESS (1 Jul 2010).
  • Wijetunge S; Hughes AD. Src family tyrosine kinases mediate hypotonicity- induced activation of L-type calcium channels in vascular smooth muscle cells. Conference on Frontiers in Cardiovascular Biology, 16 Jul 2010 - 19 Jul 2010. 87:S61-S61. OXFORD UNIV PRESS (1 Jul 2010).
  • Manickavasagar M; Wijetunge S; Ramakers BP; Pickkers P; Hughes AD. EFFECTS OF ADENOSINE ON ENDOTOXIN-INDUCED VASCULAR DYSFUNCTION IN RAT TAIL ARTERIES. 14th Annual Meeting of the European-Council-for-Cardiovascular-Research, 9 Oct 2009 - 11 Oct 2009. 54:1182-1182. LIPPINCOTT WILLIAMS & WILKINS (1 Nov 2009). Author weblink.
  • Chew FM; Wijetunge S; Hughes AD. EFFECT OF METHYLGLYOXAL ON EXPRESSION OF ENOS AND INOS IN RAT TAIL ARTERY: IMPLICATIONS FOR VASCULAR DYSFUNCTION IN DIABETES?. 14th Annual Meeting of the European-Council-for-Cardiovascular-Research, 9 Oct 2009 - 11 Oct 2009. 54:1177-1178. LIPPINCOTT WILLIAMS & WILKINS (1 Nov 2009). Author weblink.
  • Christofi F; Wijetunge S; Sever P; Hughes A. EXPRESSION OF THE TISSUE RENIN-ANGIOTENSIN SYSTEM IN HUMAN VASCULAR SMOOTH MUSCLE CELLS (VSMC'S) IN CULTURE. 19th European Meeting on Hypertension, 12 Jun 2009 - 16 Jun 2009. 27:S452-S452. LIPPINCOTT WILLIAMS & WILKINS (1 Jun 2009). Author weblink.
  • Sujenthiran A; Gulati M; Wijetunge S; Hughes A. SOLUBLE ENDOGLIN INHIBITS ENDOTHELIUM-DEPENDENT RELAXATION IN RAT ISOLATED TAIL ARTERY: A POSSIBLE LINK BETWEEN PRE-ECLAMPSIA AND ENDOTHELIAL DYSFUNCTION. 19th European Meeting on Hypertension, 12 Jun 2009 - 16 Jun 2009. 27:S217-S217. LIPPINCOTT WILLIAMS & WILKINS (1 Jun 2009). Author weblink.
  • Hughes AD; Betteridge L; Clunn G; Patel M; Schachter M; Wijetunge S. Signals evoked by angiotensin II in vascular smooth muscle cells. International Workshop on Adrenal Glands, Vascular System and Hypertension, 20 Apr 1995 - 22 Apr 1995. 89-102. SOCIETY ENDOCRINOLOGY (1 Jan 1996). Author weblink.
  • Sujenthiran A; Wijetunge S; Hughes AD. Soluble endoglin causes impaired endothelium dependent relaxation in rat tail artery: A possible pathogenic mechanism in pre-eclampsia. 12th Annual Meeting of the European-Council-for-Cardiovascular-Research. 50:810-810. (Oct 2007).
  • Kox M; Wijetunge S; Pickkers P; Hughes AD. SRC family tyrosine kinase inhibition by SU6656 reverses lipopolysaccharide-induced hyporeactivity in rat isolated tail arteries. Annual Meeting of the Dutch-Society-of-Pharmacology, 3 Oct 2005 - 5 Oct 2005. 373:94-94. SPRINGER (1 Apr 2006). Author weblink.
  • Kox M; Wijetunge S; Pickkers P; Hughes AD. The role of SRC-family tyrosine kinases in the effects of lipopolysaccharide on rat isolated tail arteries. 10th Annual Meeting of the European-Council-for-Cardiovascular-Research. 46:909-909. (Oct 2005).
  • Wijetunge S; Hughes AD. SRC-family tyrosine kinase(s) is involved in hyposmotic swelling-induced contraction of rat tail arteries. 15th European Meeting on Hypertension. 23:S347-S347. (Jun 2005).
  • Wijetunge S; Hughes AD. Mechanism of contraction of rat isolated tail arteries by hyposmotic solutions. 9th Annual Meeting of the European Council for Cardiovascular Research, 1 Oct 2004 - 3 Oct 2004. 44:588-588. LIPPINCOTT WILLIAMS & WILKINS (1 Oct 2004). Author weblink.
  • Wijetunge S; Hughes A. Hypo-osmotic swelling-induced contraction of rat tail arteries involves CaV1.2 calcium channels and protein tyrosine kinase. 14th European Meeting on Hypertension, 13 Jun 2004 - 17 Jun 2004. 22:S203-S204. LIPPINCOTT WILLIAMS & WILKINS (1 Jun 2004). Author weblink.
  • Wijetunge S; Hughes AD. Role of voltage-operated calcium channels and tyrosine kinases in the contaction of rat isolated tail artery by hyposmotic conditions. 8th Annual Meeting of the European-Council-for-Blood-Pressure-and-Cardiovascular-Research (ECCR). 42:647-647. (Oct 2003).
  • S Wijetunge; AD HUghes. An activator of c-Src tyrosine kinase (pY)EEI peptide increases voltage-operated calcium channel currents in vascular smooth muscle cells isolated from rabbit ear artery. British Society of Pharmacology (1997), 1997.
  • S Wijetunge. Contraction of rat isolated tail artery by hyposmotic solutions. ISRA, 2004.
  • Wijetunge S; Hughes AD. Inhibition of endogenous tyrosine phosphates increase voltage-operated calcium channel currents in single rabbit ear artery cells. FEBS Special Meeting, 1997.
  • S Wijetunge. Tyrosine kinases modulate voltage-operated calcium channels expressed in cos-7 cells via the α1 pore-forming subunit. International Society of Hypertension, meeting, 2002. J.Hypertens.
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