Professor William O Cookson

Publications


Journals

  • Han MK; Huang YJ; Lipuma JJ; Boushey HA; Boucher RC; Cookson WO; Curtis JL; Erb-Downward J; et alLynch SV; Sethi S; Toews GB; Young VB; Wolfgang MC; Huffnagle GB; Martinez FJ. (May 2012). Significance of the microbiome in obstructive lung disease. Thorax. 67:456-463. DOI.
  • Marth GT; Yu F; Indap AR; Garimella K; Gravel S; Leong WF; Tyler-Smith C; Bainbridge M; et alBlackwell T; Zheng-Bradley X; Chen Y; Challis D; Clarke L; Ball EV; Cibulskis K; Cooper DN; Fulton B; Hartl C; Koboldt D; Muzny D; Smith R; Sougnez C; Stewart C; Ward A; Yu J; Xue Y; Altshuler D; Bustamante CD; Clark AG; Daly M; DePristo M; Flicek P; Gabriel S; Mardis E; Palotie A; Gibbs R. (1 Jan 2011). The functional spectrum of low-frequency coding variation. GENOME BIOLOGY. 12. DOI.
  • Freidin MB; Bhudia N; Lim E; Nicholson AG; Cookson WO; Moffatt MF. (Mar 2012). Impact of collection and storage of lung tumor tissue on whole genome expression profiling. J Mol Diagn. 14:140-148. DOI.
  • Renz H; Autenrieth IB; Brandtzæg P; Cookson WO; Holgate S; von Mutius E; Valenta R; Haller D. (Dec 2011). Gene-environment interaction in chronic disease: a European Science Foundation Forward Look. J Allergy Clin Immunol. 128:S27-S49. DOI.
  • Zhang Y; Moffatt MF; Cookson WO. (Jan 2012). Genetic and genomic approaches to asthma: new insights for the origins. Curr Opin Pulm Med. 18:6-13. DOI.
  • Zhang M; Liang L; Morar N; Dixon AL; Lathrop GM; Ding J; Moffatt MF; Cookson WO; et alKraft P; Qureshi AA; Han J. (Apr 2012). Integrating pathway analysis and genetics of gene expression for genome-wide association study of basal cell carcinoma. Hum Genet. 131:615-623. DOI.
  • Stewart C; Kural D; Strömberg MP; Walker JA; Konkel MK; Stütz AM; Urban AE; Grubert F; et alLam HY; Lee WP; Busby M; Indap AR; Garrison E; Huff C; Xing J; Snyder MP; Jorde LB; Batzer MA; Korbel JO; Marth GT; 1000 Genomes Project. (Aug 2011). A comprehensive map of mobile element insertion polymorphisms in humans. PLoS Genet. 7:e1002236. DOI.
  • Cookson W; Moffatt M; Strachan DP. (Aug 2011). Genetic risks and childhood-onset asthma. J Allergy Clin Immunol. 128:266-270. DOI.
  • Danecek P; Auton A; Abecasis G; Albers CA; Banks E; DePristo MA; Handsaker RE; Lunter G; et alMarth GT; Sherry ST; McVean G; Durbin R. (1 Aug 2011). The variant call format and VCFtools. BIOINFORMATICS. 27:2156-2158. Author weblink DOI.
  • Conrad DF; Keebler JE; DePristo MA; Lindsay SJ; Zhang Y; Casals F; Idaghdour Y; Hartl CL; et alTorroja C; Garimella KV; Zilversmit M; Cartwright R; Rouleau GA; Daly M; Stone EA; Hurles ME; Awadalla P; 1000 Genomes Project. (Jul 2011). Variation in genome-wide mutation rates within and between human families. Nat Genet. 43:712-714. DOI.
  • Cookson WO; Moffatt MF. (May 2011). Genetics of complex airway disease. Proc Am Thorac Soc. 8:149-153. DOI.
  • Renz H; von Mutius E; Brandtzaeg P; Cookson WO; Autenrieth IB; Haller D. (Apr 2011). Gene-environment interactions in chronic inflammatory disease. Nat Immunol. 12:273-277. DOI.
  • Silverman EK; Vestbo J; Agusti A; Anderson W; Bakke PS; Barnes KC; Barr RG; Bleecker ER; et alBoezen HM; Burkart KM; Celli BR; Cho MH; Cookson WO; Croxton T; Daley D; DeMeo DL; Gan W; Garcia-Aymerich J; Hall IP; Hansel NN; Hersh CP; Kalsheker N; Kiley JP; Kim WJ; Lambrechts D; Lee SD; Litonjua AA; Lomas DA; London SJ; Nishimura M; Nørdestgaard BG; O'Donnell CJ; Postma DS; Puhan MA; Tesfaigzi Y; Tobin MD; Vogelmeier C; Wilk JB; Wouters E; Young RP; Ziegler-Heitbrock L; MacNee W; Crapo JD. (Apr 2011). Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD. 8:121-135. DOI.
  • Ege MJ; Mayer M; Normand AC; Genuneit J; Cookson WO; Braun-Fahrländer C; Heederik D; Piarroux R; et alvon Mutius E; GABRIELA Transregio 22 Study Group. (24 Feb 2011). Exposure to environmental microorganisms and childhood asthma. N Engl J Med. 364:701-709. DOI.
  • Holt RJ; Zhang Y; Binia A; Dixon AL; Vandiedonck C; Cookson WO; Knight JC; Moffatt MF. (Apr 2011). Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). J Allergy Clin Immunol. 127:1054-62.e1-2. DOI.
  • Ege MJ; Strachan DP; Cookson WOCM; Moffatt MF; Gut I; Lathrop M; Kabesch M; Genuneit J; et alBuechele G; Sozanska B; Boznanski A; Cullinan P; Horak E; Bieli C; Braun-Fahrlaender C; Heederik D; von Mutius E. (1 Jan 2011). Gene-environment interaction for childhood asthma and exposure to farming in Central Europe. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 127:138-U226. Author weblink DOI.
  • Ege MJ; Strachan DP; Cookson WO; Moffatt MF; Gut I; Lathrop M; Kabesch M; Genuneit J; et alBüchele G; Sozanska B; Boznanski A; Cullinan P; Horak E; Bieli C; Braun-Fahrländer C; Heederik D; von Mutius E; GABRIELA Study Group. (Jan 2011). Gene-environment interaction for childhood asthma and exposure to farming in Central Europe. J Allergy Clin Immunol. 127:138-144.e4. DOI.
  • Chambers JC; Zhang W; Sehmi J; Li X; Wass MN; Van der Harst P; Holm H; Sanna S; et alKavousi M; Baumeister SE; Coin LJ; Deng G; Gieger C; Heard-Costa NL; Hottenga JJ; Kühnel B; Kumar V; Lagou V; Liang L; Luan J; Vidal PM; Mateo Leach I; O'Reilly PF; Peden JF; Rahmioglu N; Soininen P; Speliotes EK; Yuan X; Thorleifsson G; Alizadeh BZ; Atwood LD; Borecki IB; Brown MJ; Charoen P; Cucca F; Das D; de Geus EJ; Dixon AL; Döring A; Ehret G; Eyjolfsson GI; Farrall M; Forouhi NG; Friedrich N; Goessling W; Gudbjartsson DF; Harris TB; Hartikainen AL; Heath S; Hirschfield GM; Hofman A; Homuth G; Hyppönen E; Janssen HL; Johnson T; Kangas AJ; Kema IP; Kühn JP; Lai S; Lathrop M; Lerch MM; Li Y; Liang TJ; Lin JP; Loos RJ; Martin NG; Moffatt MF; Montgomery GW; Munroe PB; Musunuru K; Nakamura Y; O'Donnell CJ; Olafsson I; Penninx BW; Pouta A; Prins BP; Prokopenko I; Puls R; Ruokonen A; Savolainen MJ; Schlessinger D; Schouten JN; Seedorf U; Sen-Chowdhry S; Siminovitch KA; Smit JH; Spector TD; Tan W; Teslovich TM; Tukiainen T; Uitterlinden AG; Van der Klauw MM; Vasan RS; Wallace C; Wallaschofski H; Wichmann HE; Willemsen G; Würtz P; Xu C; Yerges-Armstrong LM; Alcohol Genome-wide Association (AlcGen) Consortium; Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study; Genetic Investigation of Anthropometric Traits (GIANT) Consortium; Global Lipids Genetics Consortium; Genetics of Liver Disease (GOLD) Consortium; International Consortium for Blood Pressure (ICBP-GWAS); Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC); Abecasis GR; Ahmadi KR; Boomsma DI; Caulfield M; Cookson WO; van Duijn CM; Froguel P; Matsuda K; McCarthy MI; Meisinger C; Mooser V; Pietiläinen KH; Schumann G; Snieder H; Sternberg MJ; Stolk RP; Thomas HC; Thorsteinsdottir U; Uda M; Waeber G; Wareham NJ; Waterworth DM; Watkins H; Whitfield JB; Witteman JC; Wolffenbuttel BH; Fox CS; Ala-Korpela M; Stefansson K; Vollenweider P; Völzke H; Schadt EE; Scott J; Järvelin MR; Elliott P; Kooner JS. (Nov 2011). Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 43:1131-1138. DOI.
  • Ding J; Gudjonsson JE; Liang L; Stuart PE; Li Y; Chen W; Weichenthal M; Ellinghaus E; et alFranke A; Cookson W; Nair RP; Elder JT; Abecasis GR. (10 Dec 2010). Gene Expression in Skin and Lymphoblastoid Cells: Refined Statistical Method Reveals Extensive Overlap in cis-eQTL Signals. AMERICAN JOURNAL OF HUMAN GENETICS. 87:779-789. Author weblink DOI.
  • Altshuler DL; Durbin RM; Abecasis GR; Bentley DR; Chakravarti A; Clark AG; Collins FS; De la Vega FM; et alDonnelly P; Egholm M; Flicek P; Gabriel SB; Gibbs RA; Knoppers BM; Lander ES; Lehrach H; Mardis ER; McVean GA; Nickerson D; Peltonen L; Schafer AJ; Sherry ST; Wang J; Wilson RK; Gibbs RA; Deiros D; Metzker M; Muzny D; Reid J; Wheeler D; Wang J; Li J; Jian M; Li G; Li R; Liang H; Tian G; Wang B; Wang J; Wang W; Yang H; Zhang X; Zheng H; Lander ES; Altshuler DL; Ambrogio L; Bloom T; Cibulskis K; Fennell TJ; Gabriel SB; Jaffe DB; Shefler E; Sougnez CL; Bentley DR; Gormley N; Humphray S; Kingsbury Z; Koko-Gonzales P; Stone J; McKernan KJ; Costa GL; Ichikawa JK; Lee CC; Sudbrak R; Lehrach H; Borodina TA; Dahl A; Davydov AN; Marquardt P; Mertes F; Nietfeld W; Rosenstiel P; Schreiber S; Soldatov AV; Timmermann B; Tolzmann M; Egholm M; Affourtit J; Ashworth D; Attiya S; Bachorski M; Buglione E; Burke A; Caprio A; Celone C; Clark S; Conners D; Desany B; Gu L; Guccione L; Kao K; Kebbel A; Knowlton J; Labrecque M; McDade L; Mealmaker C; Minderman M; Nawrocki A; Niazi F; Pareja K; Ramenani R; Riches D; Song W; Turcotte C; Wang S; Mardis ER; Dooling D; Fulton L; Fulton R; Weinstock G; Durbin RM; Burton J; Carter DM; Churcher C; Coffey A; Cox A; Palotie A; Quail M; Skelly T; Stalker J; Swerdlow HP; Turner D; De Witte A; Giles S; Gibbs RA; Wheeler D; Bainbridge M; Challis D; Sabo A; Yu F; Yu J; Wang J; Fang X; Guo X; Li R; Li Y; Luo R; Tai S; Wu H; Zheng H; Zheng X; Zhou Y; Yang H; Marth GT; Garrison EP; Huang W; Indap A; Kural D; Lee W-P; Leong WF; Huang W; Indap A; Kural D; Lee W-P; Leong WF; Quinlan AR; Stewart C; Stromberg MP; Ward AN; Wu J; Lee C; Mills RE; Shi X; Daly MJ; DePristo MA; Altshuler DL; Ball AD; Banks E; Bloom T; Browning BL; Cibulskis K; Fennell TJ; Garimella KV; Grossman SR; Handsaker RE; Hanna M; Hartl C; Jaffe DB; Kernytsky AM; Korn JM; Li H; Maguire JR; McCarroll SA; McKenna A; Nemesh JC; Philippakis AA; Poplin RE; Price A; Rivas MA; Sabeti PC; Schaffner SF; Shefler E; Shlyakhter IA; Cooper DN; Ball EV; Mort M; Phillips AD; Stenson PD; Sebat J; Makarov V; Ye K; Yoon SC; Bustamante CD; Clark AG; Boyko A; Degenhardt J; Gravel S; Gutenkunst RN; Kaganovich M; Keinan A; Lacroute P; Ma X; Reynolds A; Clarke L; Flicek P; Cunningham F; Herrero J; Keenen S; Kulesha E; Leinonen R; McLaren W; Radhakrishnan R; Smith RE; Zalunin V; Zheng-Bradley X; Korbel JO; Stuetz AM; Humphray S; Bauer M; Cheetham RK; Cox T; Eberle M; James T; Kahn S; Murray L; Ye K; De La Vega FM; Fu Y; Hyland FCL; Manning JM; McLaughlin SF; Peckham HE; Sakarya O; Sun YA; Tsung EF; Batzer MA; Konkel MK; Walker JA; Sudbrak R; Albrecht MW; Amstislavskiy VS; Herwig R; Parkhomchuk DV; Sherry ST; Agarwala R; Khouri H; Morgulis AO; Paschall JE; Phan LD; Rotmistrovsky KE; Sanders RD; Shumway MF; Xiao C; McVean GA; Auton A; Iqbal Z; Lunter G; Marchini JL; Moutsianas L; Myers S; Tumian A; Desany B; Knight J; Winer R; Craig DW; Beckstrom-Sternberg SM; Christoforides A; Kurdoglu AA; Pearson J; Sinari SA; Tembe WD; Haussler D; Hinrichs AS; Katzman SJ; Kern A; Kuhn RM; Przeworski M; Hernandez RD; Howie B; Kelley JL; Melton SC; Abecasis GR; Li Y; Anderson P; Blackwell T; Chen W; Cookson WO; Ding J; Kang HM; Lathrop M; Liang L; Moffatt MF; Scheet P; Sidore C; Snyder M; Zhan X; Zoellner S; Awadalla P; Casals F; Idaghdour Y; Keebler J; Stone EA; Zilversmit M; Jorde L; Xing J; Eichler EE; Aksay G; Alkan C; Hajirasouliha I; Hormozdiari F; Kidd JM; Sahinalp SC; Sudmant PH; Mardis ER; Chen K; Chinwalla A; Ding L; Koboldt DC; McLellan MD; Dooling D; Weinstock G; Wallis JW; Wendl MC; Zhang Q; Durbin RM; Albers CA; Ayub Q; Balasubramaniam S; Barrett JC; Carter DM; Chen Y; Conrad DF; Danecek P; Dermitzakis ET; Hu M; Huang N; Hurles ME; Jin H; Jostins L; Keane TM; Keane TM; Le SQ; Lindsay S; Long Q; MacArthur DG; Montgomery SB; Parts L; Stalker J; Tyler-Smith C; Walter K; Zhang Y; Gerstein MB; Snyder M; Abyzov A; Abyzov A; Balasubramanian S; Bjornson R; Du J; Grubert F; Habegger L; Haraksingh R; Jee J; Khurana E; Lam HYK; Leng J; Mu XJ; Urban AE; Zhang Z; Li Y; Luo R; Marth GT; Garrison EP; Kural D; Quinlan AR; Stewart C; Stromberg MP; Ward AN; Wu J; Lee C; Mills RE; Shi X; McCarroll SA; Banks E; DePristo MA; Handsaker RE; Hartl C; Korn JM; Li H; Nemesh JC; Sebat J; Makarov V; Ye K; Yoon SC; Degenhardt J; Kaganovich M; Clarke L; Smith RE; Zheng-Bradley X; Korbel JO; Humphray S; Cheetham RK; Eberle M; Kahn S; Murray L; Ye K; De la Vega FM; Fu Y; Peckham HE; Sun YA; Batzer MA; Konkel MK; Xiao C; Iqbal Z; Desany B; Blackwell T; Snyder M; Xing J; Eichler EE; Aksay G; Alkan C; Hajirasouliha I; Hormozdiari F; Kidd JM; Chen K; Chinwalla A; Ding L; McLellan MD; Wallis JW; Hurles ME; Conrad DF; Walter K; Zhang Y; Gerstein MB; Snyder M; Abyzov A; Du J; Grubert F; Haraksingh R; Jee J; Khurana E; Lam HYK; Leng J; Mu XJ; Urban AE; Zhang Z; Gibbs RA; Bainbridge M; Challis D; Coafra C; Dinh H; Kovar C; Lee S; Muzny D; Nazareth L; Reid J; Sabo A; Yu F; Yu J; Marth GT; Garrison EP; Indap A; Leong WF; Quinlan AR; Stewart C; Ward AN; Wu J; Cibulskis K; Fennell TJ; Gabriel SB; Garimella KV; Hartl C; Shefler E; Sougnez CL; Wilkinson J; Clark AG; Gravel S; Grubert F; Clarke L; Flicek P; Smith RE; Zheng-Bradley X; Sherry ST; Khouri HM; Paschall JE; Shumway MF; Xiao C; McVean GA; Katzman SJ; Abecasis GR; Blackwell T; Mardis ER; Dooling D; Fulton L; Fulton R; Koboldt DC; Durbin RM; Balasubramaniam S; Coffey A; Keane TM; MacArthur DG; Palotie A; Scott C; Stalker J; Tyler-Smith C; Gerstein MB; Balasubramanian S; Chakravarti A; Knoppers BM; Peltonen L; Abecasis GR; Bustamante CD; Gharani N; Gibbs RA; Jorde L; Kaye JS; Kent A; Li T; McGuire AL; McVean GA; Ossorio PN; Rotimi CN; Su Y; Toji LH; Tyler-Smith C; Brooks LD; Felsenfeld AL; McEwen JE; Abdallah A; Juenger CR; Clemm NC; Collins FS; Duncanson A; Green ED; Guyer MS; Peterson JL; Schafer AJ; Abecasis GR; Altshuler DL; Auton A; Brooks LD; Durbin RM; Gibbs RA; Hurles ME; McVean GA. (28 Oct 2010). A map of human genome variation from population-scale sequencing. NATURE. 467:1061-1073. DOI.
  • Binia A; Khorasani N; Bhavsar PK; Adcock I; Brightling CE; Chung KF; Cookson WO; Moffatt MF. (Jan 2011). Chromosome 17q21 SNP and severe asthma. J Hum Genet. 56:97-98. DOI.
  • DeWan AT; Triche EW; Xu X; Hsu L-I; Zhao C; Belanger K; Hellenbrand K; Willis-Owen SAG; et alMoffatt M; Cookson WOC; Himes BE; Weiss ST; Gauderman WJ; Baurley JW; Gilliland F; Wilk JB; O'Connor GT; Strachan DP; Hoh J; Bracken MB. (1 Oct 2010). PDE11A associations with asthma: Results of a genome-wide association scan. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 126:871-U321. DOI.
  • Moffatt MF; Gut IG; Demenais F; Strachan DP; Bouzigon E; Heath S; von Mutius E; Farrall M; et alLathrop M; Cookson WO; GABRIEL Consortium. (23 Sep 2010). A large-scale, consortium-based genomewide association study of asthma. N Engl J Med. 363:1211-1221. DOI.
  • Bouzigon E; Forabosco P; Koppelman GH; Cookson WOCM; Dizier M-H; Duffy DL; Evans DM; Ferreira MAR; et alKere J; Laitinen T; Malerba G; Meyers DA; Moffatt M; Martin NG; Ng MY; Pignatti PF; Wjst M; Kauffmann F; Demenais F; Lewis CM. (1 Jun 2010). Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopy. EUROPEAN JOURNAL OF HUMAN GENETICS. 18:700-706. Author weblink DOI.
  • Mathias RA; Grant AV; Rafaels N; Hand T; Gao L; Vergara C; Tsai YJ; Yang M; et alCampbell M; Foster C; Gao P; Togias A; Hansel NN; Diette G; Adkinson NF; Liu MC; Faruque M; Dunston GM; Watson HR; Bracken MB; Hoh J; Maul P; Maul T; Jedlicka AE; Murray T; Hetmanski JB; Ashworth R; Ongaco CM; Hetrick KN; Doheny KF; Pugh EW; Rotimi CN; Ford J; Eng C; Burchard EG; Sleiman PMA; Hakonarson H; Forno E; Raby BA; Weiss ST; Scott AF; Kabesch M; Liang L; Abecasis G; Moffatt MF; Cookson WOC; Ruczinski I; Beaty TH; Barnes KC. (1 Feb 2010). A genome-wide association study on African-ancestry populations for asthma. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 125:336-346. DOI.
  • Sleiman PM; Flory J; Imielinski M; Bradfield JP; Annaiah K; Willis-Owen SA; Wang K; Rafaels NM; et alMichel S; Bonnelykke K; Zhang H; Kim CE; Frackelton EC; Glessner JT; Hou C; Otieno FG; Santa E; Thomas K; Smith RM; Glaberson WR; Garris M; Chiavacci RM; Beaty TH; Ruczinski I; Orange JS; Allen J; Spergel JM; Grundmeier R; Mathias RA; Christie JD; von Mutius E; Cookson WO; Kabesch M; Moffatt MF; Grunstein MM; Barnes KC; Devoto M; Magnusson M; Li H; Grant SF; Bisgaard H; Hakonarson H. (7 Jan 2010). Variants of DENND1B associated with asthma in children. N Engl J Med. 362:36-44. DOI.
  • Hilty M; Burke C; Pedro H; Cardenas P; Bush A; Bossley C; Davies J; Ervine A; et alPoulter L; Pachter L; Moffatt MF; Cookson WO. (2010). Disordered microbial communities in asthmatic airways. PLoS One. 5:e8578. DOI Open Access copy.
  • Sadri A; Freidin M; Bhudia N; Nicholson A; Moffat M; Cookson W; Lim E. (1 Jan 2010). How does gene expression profile for lung cancer change based on the timing of acquisition? A preliminary study. LUNG CANCER. 67:S2-S2.
  • Grossman S; Shlyakhter I; Karlsson EK; Tabrizi S; Andersen K; Rinn J; Lander E; Schaffner S; et alSabeti PC. (1 Jan 2010). Mining data from 1000 genomes to identify the causal variant in regions under positive selection. GENOME BIOLOGY. 11. Author weblink DOI.
  • Gao J; Li W; Willis-Owen SA; Jiang L; Ma Y; Tian X; Moffatt M; Cookson W; et alLin Y; Zhang Y. (2010). Polymorphisms of PHF11 and DPP10 are associated with asthma and related traits in a Chinese population. Respiration. 79:17-24. DOI.
  • Genuneit J; Cantelmo JL; Weinmayr G; Wong GWK; Cooper PJ; Riikjaerv M-A; Gotua M; Kabesch M; et alvon Mutius E; Forastiere F; Crane J; Nystad W; El-Sharif N; Batlles-Garrido J; Garcia-Marcos L; Garcia-Hernandez G; Morales-Suarez-Varela M; Nilsson L; Braback L; Saraclar Y; Weiland SK; Cookson WOC; Strachan D; Moffatt MF. (1 Dec 2009). A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. CLINICAL AND EXPERIMENTAL ALLERGY. 39:1875-1888. Author weblink DOI.
  • Genuneit J; Cantelmo JL; Weinmayr G; Wong GW; Cooper PJ; Riikjärv MA; Gotua M; Kabesch M; et alvon Mutius E; Forastiere F; Crane J; Nystad W; El-Sharif N; Batlles-Garrido J; García-Marcos L; García-Hernández G; Morales-Suarez-Varela M; Nilsson L; Bråbäck L; Saraçlar Y; Weiland SK; Cookson WO; Strachan D; Moffatt MF; ISAAC Phase 2 Study Group. (Dec 2009). A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. Clin Exp Allergy. 39:1875-1888. DOI.
  • Mathias RA; Grant AV; Rafaels N; Hand T; Gao L; Vergara C; Tsai YJ; Yang M; et alCampbell M; Foster C; Gao P; Togias A; Hansel NN; Diette G; Adkinson NF; Liu MC; Faruque M; Dunston GM; Watson HR; Bracken MB; Hoh J; Maul P; Maul T; Jedlicka AE; Murray T; Hetmanski JB; Ashworth R; Ongaco CM; Hetrick KN; Doheny KF; Pugh EW; Rotimi CN; Ford J; Eng C; Burchard EG; Sleiman PM; Hakonarson H; Forno E; Raby BA; Weiss ST; Scott AF; Kabesch M; Liang L; Abecasis G; Moffatt MF; Cookson WO; Ruczinski I; Beaty TH; Barnes KC. (Feb 2010). A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol. 125:336-346.e4. DOI.
  • Harper JI; Godwin H; Green A; Wilkes LE; Holden NJ; Moffatt M; Cookson WO; Layton G; et alChandler S. (1 Feb 2010). A study of matrix metalloproteinase expression and activity in atopic dermatitis using a novel skin wash sampling assay for functional biomarker analysis. Br J Dermatol. 162:397-403. DOI.
  • Yates L; McMurray F; Zhang Y; Greenfield A; Moffatt M; Cookson W; Dean C. (Aug 2009). ENU mutagenesis as a tool for understanding lung development and disease. Biochem Soc Trans. 37:838-842. DOI.
  • Himes BE; Hunninghake GM; Baurley JW; Rafaels NM; Sleiman P; Strachan DP; Wilk JB; Willis-Owen SAG; et alKlanderman B; Lasky-Su J; Lazarus R; Murphy AJ; Soto-Quiros ME; Avila L; Beaty T; Mathias RA; Ruczinski I; Barnes KC; Celedon JC; Cookson WOC; Gauderman WJ; Gilliland FD; Hakonarson H; Lange C; Moffatt MF; O'Connor GT; Raby BA; Silverman EK; Weiss ST. (15 May 2009). Genome-wide Association Analysis Identifies PDE4D as an Asthma-Susceptibility Gene. AMERICAN JOURNAL OF HUMAN GENETICS. 84:581-593. Author weblink DOI.
  • Cookson W; Liang L; Abecasis G; Moffatt M; Lathrop M. (Mar 2009). Mapping complex disease traits with global gene expression. Nat Rev Genet. 10:184-194. DOI.
  • Taylor JM; Street TL; Hao L; Copley R; Taylor MS; Hayden PJ; Stolper G; Mott R; et alHein J; Moffatt MF; Cookson WO. (2009). Dynamic and physical clustering of gene expression during epidermal barrier formation in differentiating keratinocytes. PLoS One. 4:e7651. DOI Open Access copy.
  • Willis-Owen SA; Cookson WO; Moffatt MF. (Jan 2009). Genome-wide association studies in the genetics of asthma. Curr Allergy Asthma Rep. 9:3-9.
  • Weinmayr G; Forastiere F; Weiland SK; Rzehak P; Abramidze T; Annesi-Maesano I; Björkstén B; Brunekreef B; et alBüchele G; Cookson WO; von Mutius E; Pistelli R; Strachan DP; ISAAC Phase Two Study Group. (Nov 2008). International variation in prevalence of rhinitis and its relationship with sensitisation to perennial and seasonal allergens. Eur Respir J. 32:1250-1261. DOI.
  • Weidinger S; Gieger C; Rodriguez E; Baurecht H; Mempel M; Klopp N; Gohlke H; Wagenpfeil S; et alOllert M; Ring J; Behrendt H; Heinrich J; Novak N; Bieber T; Kraemer U; Berdel D; von Berg A; Bauer CP; Herbarth O; Koletzko S; Prokisch H; Mehta D; Meitinger T; Depner M; von Mutius E; Liang L; Moffatt M; Cookson W; Kabesch M; Wichmann H-E; Illig T. (1 Aug 2008). Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus. PLOS GENETICS. 4. Author weblink DOI.
  • Moffatt MF; Cookson WO. (17 Apr 2008). Asthma and chitinases. N Engl J Med. 358:1725-1726. DOI.
  • Williams H; Stewart A; von Mutius E; Cookson W; Anderson HR; International Study of Asthma and Allergies in Childhood (ISAAC) Phase One and Three Study Groups. (Apr 2008). Is eczema really on the increase worldwide?. J Allergy Clin Immunol. 121:947-54.e15. DOI.
  • Flohr C; Weiland SK; Weinmayr G; Björkstén B; Bråbäck L; Brunekreef B; Büchele G; Clausen M; et alCookson WO; von Mutius E; Strachan DP; Williams HC; ISAAC Phase Two Study Group. (Jan 2008). The role of atopic sensitization in flexural eczema: findings from the International Study of Asthma and Allergies in Childhood Phase Two. J Allergy Clin Immunol. 121:141-147.e4. DOI.
  • Dixon AL; Liang L; Moffatt MF; Chen W; Heath S; Wong KC; Taylor J; Burnett E; et alGut I; Farrall M; Lathrop GM; Abecasis GR; Cookson WO. (Oct 2007). A genome-wide association study of global gene expression. Nat Genet. 39:1202-1207. DOI.
  • Weinmayr G; Weiland SK; Björkstén B; Brunekreef B; Büchele G; Cookson WO; Garcia-Marcos L; Gotua M; et alGratziou C; van Hage M; von Mutius E; Riikjärv MA; Rzehak P; Stein RT; Strachan DP; Tsanakas J; Wickens K; Wong GW; ISAAC Phase Two Study Group. (15 Sep 2007). Atopic sensitization and the international variation of asthma symptom prevalence in children. Am J Respir Crit Care Med. 176:565-574. DOI.
  • Moffatt MF; Kabesch M; Liang L; Dixon AL; Strachan D; Heath S; Depner M; von Berg A; et alBufe A; Rietschel E; Heinzmann A; Simma B; Frischer T; Willis-Owen SA; Wong KC; Illig T; Vogelberg C; Weiland SK; von Mutius E; Abecasis GR; Farrall M; Gut IG; Lathrop GM; Cookson WO. (26 Jul 2007). Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature. 448:470-473. DOI.
  • Morar N; Cookson WO; Harper JI; Moffatt MF. (Jul 2007). Filaggrin mutations in children with severe atopic dermatitis. J Invest Dermatol. 127:1667-1672. DOI.
  • Valdar W; Solberg LC; Gauguier D; Cookson WO; Rawlins JN; Mott R; Flint J. (Oct 2006). Genetic and environmental effects on complex traits in mice. Genetics. 174:959-984. DOI.
  • Valdar W; Solberg LC; Gauguier D; Burnett S; Klenerman P; Cookson WO; Taylor MS; Rawlins JN; et alMott R; Flint J. (Aug 2006). Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet. 38:879-887. DOI.
  • Cookson WO. (Aug 2006). State of the art. Genetics and genomics of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 3:473-475. DOI.
  • Hopkin J; Cookson W. (Jul 2006). Genetic variation in the beta subunit of the high affinity IgE receptor and atopy and asthma. Clin Exp Allergy. 36:855-857. DOI.
  • Morar N; Willis-Owen SA; Moffatt MF; Cookson WO. (Jul 2006). The genetics of atopic dermatitis. J Allergy Clin Immunol. 118:24-34. DOI.
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  • James ES; Harney S; Wordsworth BP; Cookson WO; Davis SJ; Moffatt MF. (Aug 2005). PDCD1: a tissue-specific susceptibility locus for inherited inflammatory disorders. Genes Immun. 6:430-437. DOI.
  • McGovern DP; Hysi P; Ahmad T; van Heel DA; Moffatt MF; Carey A; Cookson WO; Jewell DP. (15 May 2005). Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. Hum Mol Genet. 14:1245-1250. DOI.
  • Moffatt M; Hysi P; Cookson W. (15 May 2005). Haplotypes and asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 171:1066-1067. Author weblink DOI.
  • Hysi P; Kabesch M; Moffatt MF; Schedel M; Carr D; Zhang Y; Boardman B; von Mutius E; et alWeiland SK; Leupold W; Fritzsch C; Klopp N; Musk AW; James A; Nunez G; Inohara N; Cookson WO. (1 Apr 2005). NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet. 14:935-941. DOI.
  • Kurz T; Altmueller J; Strauch K; Rüschendorf F; Heinzmann A; Moffatt MF; Cookson WO; Inacio F; et alNürnberg P; Stassen HH; Deichmann KA. (Feb 2005). A genome-wide screen on the genetics of atopy in a multiethnic European population reveals a major atopy locus on chromosome 3q21.3. Allergy. 60:192-199. DOI.
  • Cookson W. (Dec 2004). The immunogenetics of asthma and eczema: a new focus on the epithelium. Nat Rev Immunol. 4:978-988. DOI.
  • Weiland SK; Björkstén B; Brunekreef B; Cookson WO; von Mutius E; Strachan DP; International Study of Asthma and Allergies in Childhood Phase II Study Group. (Sep 2004). Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II): rationale and methods. Eur Respir J. 24:406-412. DOI.
  • Kauffmann F; Anto J; Baur MP; Bickeboller H; Clayton D; Cookson WOC; Demenais F; Helms PJ; et alHumphery-Smith I; Imbeaud S; Kauffmann F; Knoppers BM; Lathrop M; Little J; Pearce N; Schaid D; Silverman E; Weiss S; Wjst M. (1 Sep 2004). Post-genome respiratory epidemiology: a multidisciplinary challenge. EUROPEAN RESPIRATORY JOURNAL. 24:471-480. Author weblink DOI.
  • Bowcock AM; Cookson WO. (1 Apr 2004). The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. Hum Mol Genet. 13 Spec No 1:R43-R55. DOI.
  • Cookson W; Moffatt M. (2004). Making sense of asthma genes. N Engl J Med. 351:1794-1796.
  • Allen M; Heinzmann A; Noguchi E; Abecasis G; Broxholme J; Ponting CP; Bhattacharyya S; Tinsley J; et alZhang Y; Holt R; Jones EY; Lench N; Carey A; Jones H; Dickens NJ; Dimon C; Nicholls R; Baker C; Xue L; Townsend E; Kabesch M; Weiland SK; Carr D; von Mutius E; Adcock IM; Barnes PJ; Lathrop GM; Edwards M; Moffatt MF; Cookson WO. (Nov 2003). Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet. 35:258-263. DOI.
  • Traherne JA; Hill MR; Hysi P; D'Amato M; Broxholme J; Mott R; Moffatt MF; Cookson WO. (15 Oct 2003). LD mapping of maternally and non-maternally derived alleles and atopy in FcepsilonRI-beta. Hum Mol Genet. 12:2577-2585. DOI.
  • Chapman SJ; Cookson WO; Musk AW; Lee YC. (Jul 2003). Benign asbestos pleural diseases. Curr Opin Pulm Med. 9:266-271.
  • Zhang Y; Leaves NI; Anderson GG; Ponting CP; Broxholme J; Holt R; Edser P; Bhattacharyya S; et alDunham A; Adcock IM; Pulleyn L; Barnes PJ; Harper JI; Abecasis G; Cardon L; White M; Burton J; Matthews L; Mott R; Ross M; Cox R; Moffatt MF; Cookson WO. (Jun 2003). Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat Genet. 34:181-186. DOI.
  • Donnadieu E; Jouvin MH; Rana S; Moffatt MF; Mockford EH; Cookson WO; Kinet JP. (May 2003). Competing functions encoded in the allergy-associated F(c)epsilonRIbeta gene. Immunity. 18:665-674.
  • Cookson W. (Apr 2003). A new gene for asthma: would you ADAM and Eve it?. Trends Genet. 19:169-172.
  • Moffatt MF; Faux JA; Lester S; Pare P; McCluskey J; Spargo R; James A; Musk AW; et alCookson WOCM. (15 Mar 2003). Atopy, respiratory function and HLA-DR in aboriginal Australians. HUMAN MOLECULAR GENETICS. 12:625-630. Author weblink DOI.
  • Moffatt MF; Faux JA; Lester S; Paré P; McCluskey J; Spargo R; James A; Musk AW; et alCookson WO. (15 Mar 2003). Atopy, respiratory function and HLA-DR in Aboriginal Australians. Hum Mol Genet. 12:625-630.
  • Cookson W. (Dec 2002). Genetics and genomics of asthma and allergic diseases. Immunol Rev. 190:195-206.
  • Cookson WO; Moffatt MF. (Oct 2002). The genetics of atopic dermatitis. Curr Opin Allergy Clin Immunol. 2:383-387.
  • van Hage-Hamsten M; Johansson E; Kronqvist M; Loughry A; Cookson WO; Moffatt MF. (Jun 2002). Associations of Fc epsilon R1-beta polymorphisms with immunoglobin E antibody responses to common inhalant allergens in a rural population. Clin Exp Allergy. 32:838-842.
  • Anderson GG; Leaves NI; Bhattacharyya S; Zhang YM; Walshe V; Broxholme J; Abecasis G; Levy E; et alZimmer M; Cox R; Cookson WOCM. (1 Apr 2002). Positive association to IgE levels and a physical map of the 13q14 atopy locus. EUROPEAN JOURNAL OF HUMAN GENETICS. 10:266-270. Author weblink DOI.
  • Anderson GG; Leaves NI; Bhattacharyya S; Zhang Y; Walshe V; Broxholme J; Abecasis G; Levy E; et alZimmer M; Cox R; Cookson WO. (Apr 2002). Positive association to IgE levels and a physical map of the 13q14 atopy locus. Eur J Hum Genet. 10:266-270. DOI.
  • Leaves NI; Bhattacharyya S; Wiltshire S; Cookson WOCM. (1 Mar 2002). A detailed genetic map of the chromosome 7 bronchial hyper-responsiveness locus. EUROPEAN JOURNAL OF HUMAN GENETICS. 10:177-182. Author weblink DOI.
  • Leaves NI; Bhattacharyya S; Wiltshire S; Cookson WO. (Mar 2002). A detailed genetic map of the chromosome 7 bronchial hyper-responsiveness locus. Eur J Hum Genet. 10:177-182. DOI.
  • Cookson WO. (Mar 2002). Asthma genetics. Chest. 121:7S-13S.
  • Zhang Y; Cookson W. (2002). A case study of QTL analysis in a mouse model of asthma. Methods Mol Biol. 195:253-279. DOI.
  • Bracken MB; Belanger K; Cookson WO; Triche E; Christiani DC; Leaderer BP. (2002). Genetic and perinatal risk factors for asthma onset and severity: a review and theoretical analysis. Epidemiol Rev. 24:176-189.
  • Abecasis GR; Cherny SS; Cookson WO; Cardon LR. (Jan 2002). Merlin--rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet. 30:97-101. DOI.
  • Walley AJ; Chavanas S; Moffatt MF; Esnouf RM; Ubhi B; Lawrence R; Wong K; Abecasis GR; et alJones EY; Harper JI; Hovnanian A; Cookson WO. (Oct 2001). Gene polymorphism in Netherton and common atopic disease. Nat Genet. 29:175-178. DOI.
  • Cárdaba B; Moffatt MF; Fernández E; Jurado A; Rojo M; García M; Ansotegui IJ; Cortegano I; et alArrieta I; Etxenagusia MA; del Pozo V; Urraca J; Aceituno E; Gallardo S; Palomino P; Cookson W; Lahoz C. (Aug 2001). Allergy to dermatophagoides in a group of Spanish gypsies: genetic restrictions. Int Arch Allergy Immunol. 125:297-306.
  • Abecasis GR; Cherny SS; Cookson WO; Cardon LR. (Aug 2001). GRR: graphical representation of relationship errors. Bioinformatics. 17:742-743.
  • Cookson WO. (Jul 2001). The genetics of atopic dermatitis: strategies, candidate genes, and genome screens. J Am Acad Dermatol. 45:S7-S9.
  • Abecasis GR; Cookson WO; Cardon LR. (Jun 2001). The power to detect linkage disequilibrium with quantitative traits in selected samples. Am J Hum Genet. 68:1463-1474. DOI.
  • Moffatt MF; Schou C; Faux JA; Abecasis GR; James A; Musk AW; Cookson WO. (May 2001). Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample. Eur J Hum Genet. 9:341-346. DOI.
  • Cookson WO; Ubhi B; Lawrence R; Abecasis GR; Walley AJ; Cox HE; Coleman R; Leaves NI; et alTrembath RC; Moffatt MF; Harper JI. (Apr 2001). Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat Genet. 27:372-373. DOI.
  • Palmer LJ; Cookson WO; James AL; Musk AW; Burton PR. (Apr 2001). Gibbs sampling-based segregation analysis of asthma-associated quantitative traits in a population-based sample of nuclear families. Genet Epidemiol. 20:356-372. DOI.
  • Palmer LJ; Barnes KC; Burton PR; Chen H; Cookson WO; Collaborative Study on the Genetics of Asthma; Deichmann KA; Elston RC; et alHolloway JW; Jacobs KB; Laitinen T; Wjst M. (1 Apr 2001). Meta-analysis for linkage to asthma and atopy in the chromosome 5q31-33 candidate region. Hum Mol Genet. 10:891-899.
  • Walley AJ; Wiltshire S; Ellis CM; Cookson WO. (15 Feb 2001). Linkage and allelic association of chromosome 5 cytokine cluster genetic markers with atopy and asthma associated traits. Genomics. 72:15-20. DOI.
  • Palmer L; Lonjou C; Barnes K; Chen H; Cookson WO; Deichmann KA; Holloway JW; Laitinen T; et alWjst M; Morton NE. (Jan 2001). A retrospective collaboration on chromosome 5 by the International Consortium on Asthma Genetics (COAG). Clin Exp Allergy. 31:152-154.
  • Abecasis GR; Cardon LR; Cookson WO; Sham PC; Cherny SS. (2001). Association analysis in a variance components framework. Genet Epidemiol. 21 Suppl 1:S341-S346.
  • Abecasis GR; Noguchi E; Heinzmann A; Traherne JA; Bhattacharyya S; Leaves NI; Anderson GG; Zhang Y; et alLench NJ; Carey A; Cardon LR; Moffatt MF; Cookson WO. (Jan 2001). Extent and distribution of linkage disequilibrium in three genomic regions. Am J Hum Genet. 68:191-197. DOI.
  • Cookson WO; Abeçasis GR. (2001). Oxford genome screen for asthma-associated traits. Genet Epidemiol. 21 Suppl 1:S1-S3.
  • Palmer LJ; Cookson WO; Deichmann KA; Holloway JW; Laitinen T. (2001). Single region linkage analyses of asthma: description of data sets. Genet Epidemiol. 21 Suppl 1:S9-15.
  • Cherny SS; Abecasis GR; Cookson WO; Sham PC; Cardon LR. (2001). The effect of genotype and pedigree error on linkage analysis: analysis of three asthma genome scans. Genet Epidemiol. 21 Suppl 1:S117-S122.
  • Palmer LJ; Cookson WO. (2001). Using single nucleotide polymorphisms as a means to understanding the pathophysiology of asthma. Respir Res. 2:102-112.
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  • Kurz T; Strauch K; Heinzmann A; Braun S; Jung M; Rüschendorf F; Moffatt MF; Cookson WO; et alInacio F; Ruffilli A; Nordskov-Hansen G; Peltre G; Forster J; Kuehr J; Reis A; Wienker TF; Deichmann KA. (Nov 2000). A European study on the genetics of mite sensitization. J Allergy Clin Immunol. 106:925-932. DOI.
  • Young RP; Barker RD; Pile KD; Cookson WO; Taylor AJ. (Jan 1995). The association of HLA-DR3 with specific IgE to inhaled acid anhydrides. Am J Respir Crit Care Med. 151:219-221.
  • Stafford AN; Rider SH; Hopkin JM; Cookson WO; Monaco AP. (May 1994). A 2.8 Mb YAC contig in 11q12-q13 localizes candidate genes for atopy: Fc epsilon RI beta and CD20. Hum Mol Genet. 3:779-785.

Conferences

  • Williams HC; Stewart A; von Mutius E; Cookson W; Anderson HR. International study of asthma and allergies in childhood (ISAAC) phase 1 and 3 study groups. Annual Meeting of the British-Society-for-Investigative-Dermatology, 16 Apr 2007 - 18 Apr 2007. 156:1109-1109. BLACKWELL PUBLISHING (1 May 2007). Author weblink.
  • Morar N; Edster P; Street TL; Weidinger S; Di W; Dixon AL; Taylor M; Holt R; et alBroxholme J; Kloop N; Novak N; Bockelbrinck A; Ragoussis J; Illig T; Harper JI; Cookson WO; Moffatt MF. Positional cloning of susceptibility genes for atopic dermatitis in the epidermal differentiation complex. 68th Annual Meeting of the Society-for-Investigative-Dermatology, 9 May 2007 - 12 May 2007. 127:S89-S89. NATURE PUBLISHING GROUP (1 Apr 2007). Author weblink.
  • Weinmayr G; Buechele G; Nagel G; Bjoerksten B; Brunekreef B; Cookson WOC; Von Mutius E; Strachan DP; et alAnnesi-Maesano I; Elsharif N; Wickens K; Weiland SK. Indoor air pollutants from heating and cooking in relation to asthma symptoms in children: Results from phase II of the international study of asthma and allergy in childhood (ISAAC II). ISEE/ISEA 2006 Conference, 2006. 17:S231-S232. LIPPINCOTT WILLIAMS & WILKINS (1 Nov 2006). Author weblink DOI.
  • Morar N; Harper JI; Cookson WO; Moffatt MF. Filaggrin mutations in atopic dermatitis. 36th Annual Meeting of the European-Society-of-Dermatology-Research (ESDR). 126:38-38. (Aug 2006).
  • Moffatt MF; Allen MH; Reynolds NJ; Meggitt ST; Cookson WO; Barker JN. A case-control study investigating candidate genes in adult eczema. 35th Annual Meeting of the European-Society-for-Dermatological-Research. 125:A22-A22. (Sep 2005).
  • Morar N; Bowcock AM; Harper J; Cookson WO; Moffatt MF. Investigation of the chromosome 17q25 PSORS2 locus in atopic dermatitis. 35th Annual Meeting of the European-Society-for-Dermatological-Research. 125:A25-A25. (Sep 2005).
  • Street TL; Hayden PJ; Hao L; Taylor J; Copley R; Kubilus H; Klausner M; Moffatt M; et alCookson WO. Analysis of global gene expression profile changes during differentiation of the EpiDerM (TM) in vitro human skin equivalent. 66th Annual Meeting of the Society-for-Investigative-Dermatology, 4 May 2005 - 7 May 2005. 124:A79-A79. BLACKWELL PUBLISHING INC (1 Apr 2005). Author weblink.
  • Cookson WOC. Asthma genetics. 44th Annual Thomas L Petty Aspen Lung Conference, 6 Jun 2001 - 9 Jun 2001. 121:7S-13S. AMER COLL CHEST PHYSICIANS (1 Mar 2002). Author weblink DOI.
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