Faculty of Medicine

Recent relevant publications

Gillies, G. E., McArthur S “Estrogen actions in the brain and the bases for differential actions in men and women: a case for sex-specific medicines”. Pharmacological Reviews (2010)  in press

Gillies, G. E. McArthur, S. “Independent influences of sex steroids of systemic and central origin in a rat model of Parkinson’s disease: a contribution to sex-specific neuroprotection by estrogens. Hormones and Behaviour. Review (2010) 57: 23-34.

Solito E.S., McArthur S., Christian H., Gavins, F., Buckingham, J.C., Gillies, G.E. “Annexin A1 in the brain – undiscovered roles?. Trends Pharmacol Sci (2008), 29(3): 135-142.

McArthur, S., McHale E., Gillies G.E.  “The size and distribution of midbraindopaminergic
populations are permanently altered by perinatal glucocorticoid exposure in a sex- region
and time-specific manner”. Neuropsychopharmacology (2007), 32: 1462-1476.

McArthur S, Murray, H.E. Dexter D. & Gillies G.  “Striatal susceptibility to dopaminergic neurotoxins is independent of sex hormone effects on cell survival and DAT expression but exacerbated by central aromatase inhibition”. J.Neurochem. (2007), 100: 678-692.

Warne, J.P., John, C. D., Christian H., C., Morris, J.F., Flower, R.J., Sugden D., Solito E., Gillies, G.E. & Buckingham, J.C. (2006).  Gene deletion reveals roles for annexin 1 in the regulation of lipolysis and interleukin 6 release in visceral adipose tissue. Am J. Physiol. Endocrinol Metab. (2006) 291: E1264-1273.

McArthur, S., Siddique, Z-L., Capone, G., Christian H.C., Theogaraj, C.D., John, C.D., Smith S.F., Morris, J.F., Buckingham, J.C., Gillies G.E. “Perinatal glucocorticoid treatment disrupts the hypothalamo-lactotroph axis in adult female but not male rats”. Endocrinology (2006), 147: 1904-15

McArthur, S.R., McHale E., Dalley J., Buckingham, J.C. & Gillies, G.E. "Altered mesencephalic dopaminergic populations in adulthood as a consequence of brief perinatal glucocorticoid exposure".  J. Neuroendocrinology (2005), 17 (8): 475-82. 

Gillies GE, Murray HE, Dexter D, McArthur S. Sex dimorphisms in the neuroprotective effects of estrogen in an animal model of Parkinson’s disease”. Pharmacol Biochem Behav. (2004), 78: 513-22.

Datla KP, Murray H.E., Pillai AV, Gillies GE and Dexter DT. “Differences in the susceptibilty of the nigrostriatal dopaminergic pathway to the neurotoxin 6-OHDA during the estrous cycle.”  Neuroreport (2003), 14: 47-50.

Murray, H.E., Pillai, A.V., McArthur, S.R., Razvi, N.,Datla,., K.P., Dexter, D.T. and Gillies, G.E.  “Dose- and sex-dependent effects of the neurotoxin 6-OHDA on the nigrostriatal dopaminergic pathway of adult rats: differential actions of estrogen in males and females”.  Neuroscience  (2003), 116: 213-222.

Pannell, C., Simonian, S. X., Gillies, G. E., Luscher, B., Herbison A. E. “ Hypothalamic somatostatin and growth hormone releasing hormone mRNA expression depend upon GABAA receptor expresion in the developing mouse. Neuroendocrinology (2002), 76: 93-98.

Murray, H.E., Rantle, C.M., Simonian, S.X., Herbison, A.E. and Gillies, G.E. "Sexually dimorphic ontogeny of GABAergic influences on periventricular somatostatin neurons" Neuroendocrinology (1999),  70: 384-391.

Christian, M. and Gillies, G. "Developing hypothalamic neurones as potential targets for environmental estrogens"  J.Endocrinology 160, (1999), R1 – R6.

Murray, H.E., Simonian, S.X., Herbison, A.E. and Gillies, G.E.  "Ontogeny and sexual differentiation of somatostatin biosynthesis and secretion in the hypothalamic periventricular-median eminence pathway"  J. Neuroendocrinology 11, (1999), 35-42

Murray, H.E., Simonian, S.X., Herbison, A.E. and Gillies, G.E. "Correlation of hypothalamic somatostatin mRNA and peptide content with secretion: sexual dimorphism and differential regulation by gonadal factors"  J. Neuroendocrinology 11, (1999), 27-33.

Simonian, S.X., Murray, H.E., Gillies, G.E. and Herbison, A.E.  "Estrogen-dependent ontogeny of sex differences in somatostatin neurons of the hypothalamic periventricular nucleus"  Endocrinology 139, (1997), 1420-1429.

Murray, H.E. and  Gillies, G.E.  "Differential effects of neuroactive steroids on somatostatin and dopamine secretion from primary hypothalamic cell cultures"  J. Neuroendocrinology  9,  (1997)  287-295.

Gillies, G.E. "Somatostatin: the neuroendocrine story"  TiPS  18,  (1997), 87-95.

Murray, H.E. and Gillies, G.E.  "Investigation of the ontogenetic patterns of rat hypothalamic dopaminergic neurone morphology and function in vitro" J. Endocrinology 139, (1993), 403-414.

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