Cartoid Atherosclerosis
Professor Carlo di Mario, Principal Investigator
Research areas include:
| New drug eluting stents: comparison of sirolimus eluting and paclitaxel eluting stents, safety and efficacy of a new tacrolimus eluting (JANUS) and paclitaxel eluting stent with a biodegradable polymer (COSTAR) in the setting of multicentre controlled randomized trials. |
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Biodegradable stents: Metal (magnesium) alloy stents to prevent recoil and seal dissections with full degradation after 8 weeks solving the problem of side branch access, late malapposition (UK Principal Investigator, protocol under evaluation MHRA) |
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Pharmacodynamics of the delivery (iv and ic) of Apolipoprotein A1 Milan in a rabbit model of cartoid atherosclerosis, in cooperation with Pfizer, performed in the Institute of Pharmacology, Milan University. |
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| Correlation of enzymatic release and volume of late Gadolinium enhancement in patients with non-ST elevation myocardial infarction: prevention of further embolisation using a proximal occlusion balloon: a serial study with cardial magnetic resonance (protocol in development in cooperation with Proxis, Minneapolis). |
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CARESS in AMI: randomized trial of facilitated PTCA vs. thrombolysis and rescue PTCA in patients admitted to hospitals without PTCA facilities, Study Chairman, Sponsors: Lilly and Biotronik. Data management and statistical analysis provided by the Clinical Trial Unit of the Royal Brompton Hospital. |
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Intravascular ultrasound guidance of the implantation of paclitaxel eluting stents for ostial stenosis (sponsored by CRC Dec 2004), submitted RB&H LEC Feb 16 2005). |
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