National Heart & Lung Institute (NHLI)

Publications

Selected publications:
  • Lozano E; Frasa MAM; Smolarczyk K; Knaus,UG; Braga VMM. (Mar 2008)  PAK is required for the disruption of cadherin adhesion by the small Rac GTPase.  J.Cell Sci. 121:933-938. http://jcs.biologists.org/cgi/content/full/121/7/933
  • Zhang J; Betson M; Erasmus J; Zeikos K; Bailly M; Cramer LP; Braga VM. (01 Dec 2005). Actin at cell-cell junctions is composed of two dynamic and functional populations. J Cell Sci. 118:5549-5562. Publisher weblink DOI.
  • Pratt SJ; Epple H; Ward M; Feng Y; Braga VM; Longmore GD. (28 Feb 2005). The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration. J Cell Biol. 168:813-824. Publisher weblink DOI.
  • Hogan C; Serpente N; Cogram P; Hosking CR; Bialucha CU; Feller SM; Braga VM; Birchmeier W; Fujita Y. (Aug 2004). Rap1 regulates the formation of E-cadherin-based cell-cell contacts. Mol Cell Biol. 24:6690-6700. Publisher weblink DOI.
  • Marie H; Pratt SJ; Betson M; Epple H; Kittler JT; Meek L; Moss SJ; Troyanovsky S; Attwell D; Longmore GD; et al. (10 Jan 2003). The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin. J Biol Chem. 278:1220-1228. Publisher weblink DOI.
  • Betson M; Lozano E; Zhang J; Braga VM. (04 Oct 2002). Rac activation upon cell-cell contact formation is dependent on signaling from the epidermal growth factor receptor. J Biol Chem. 277:36962-36969. Publisher weblink DOI.
  • Lampugnani MG; Zanetti A; Breviario F; Balconi G; Orsenigo F; Corada M; Spagnuolo R; Betson M; Braga V; Dejana E. (Apr 2002). VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam. Mol Biol Cell. 13:1175-1189. Publisher weblink DOI.
  • Braga VM; Betson M; Li X; Lamarche-Vane N. (Nov 2000). Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes. Mol Biol Cell. 11:3703-3721. Publisher weblink.
  • Espada J; Pérez-Moreno M; Braga VM; Rodriguez-Viciana P; Cano A. (06 Sep 1999). H-Ras activation promotes cytoplasmic accumulation and phosphoinositide 3-OH kinase association of beta-catenin in epidermal keratinocytes. J Cell Biol. 146:967-980. Publisher weblink.
  • Weil M; Raff MC; Braga VM. (08 Apr 1999). Caspase activation in the terminal differentiation of human epidermal keratinocytes. Curr Biol. 9:361-364. Publisher weblink.
  • Braga VM; Del Maschio A; Machesky L; Dejana E. (Jan 1999). Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context. Mol Biol Cell. 10:9-22. Publisher weblink.
  • Braga VM; Machesky LM; Hall A; Hotchin NA. (16 Jun 1997). The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol. 137:1421-1431. Publisher weblink.
 Reviews:
  • Braga VM; Yap AS. (Oct 2005). The challenges of abundance: epithelial junctions and small GTPase signalling. Curr Opin Cell Biol. 17:466-474. Publisher weblink DOI.
  • Lozano E; Betson M; Braga VM. (May 2003). Tumor progression: Small GTPases and loss of cell-cell adhesion. Bioessays. 25:452-463. Publisher weblink DOI.
  • Harwood A; Braga VM. (Apr 2003). Cdc42 & GSK-3: signals at the crossroads. Nat Cell Biol. 5:275-277. Publisher weblink DOI.
  • Braga VM. (Oct 2002). Cell-cell adhesion and signalling. Curr Opin Cell Biol. 14:546-556. Publisher weblink.
  • Braga VM. (Aug 2002). GEF without a Dbl domain?. Nat Cell Biol. 4:E188-E190. Publisher weblink DOI.
  • Braga V; Harwood AJ. (Jul 2001). 'Super glue'. Nat Cell Biol. 3:E168-E170. Publisher weblink DOI.
  • Braga V. (25 Nov 2000). Epithelial cell shape: cadherins and small GTPases. Exp Cell Res. 261:83-90. Publisher weblink DOI.
  • Braga V. (Oct 2000). The crossroads between cell-cell adhesion and motility. Nat Cell Biol. 2:E182-E184. Publisher weblink DOI.
  • Braga VM. (Aug 1999). Small GTPases and regulation of cadherin dependent cell-cell adhesion. Mol Pathol. 52:197-202. Publisher weblink

 

Chapters in books
  • Braga, VMM; Balda, M. Eds: Braga VMM and Balda M. Regulation of Cell Adhesion - Seminars in Cell and Developmental Biology. Elsevier (2004).  
  • Fujita, Y; Braga, VMM. Epithelial cell shape and Rho small GTPases. Signalling Networks in Cell Shape and Motility, Singapore. 261:144-158. Novartis Foundation Symposium, Singapore (2005)
  • Fujita, Y; Hogan, C; Braga, V M M. Regulation of cell-cell adhesion by Rap1. In Methods in Enzymology. 407:359-372. Eds: C. Der. Elsevier (2006).
  • Erasmus, J; Braga, VMM. Rho GTPase activation by cell-cell adhesion. In Methods in Enzymology. 406:402-415. Eds: C. Der and A. Hall. Elsevier (2006).
  • Braga, V.; Betson, M.E. Cell-cell adhesion. In Rho GTPses. Eds: M. Symons. Landes Bioscience and Eurekah.com (2003). Author weblink.
  • Braga V. Cadherin adhesion regulation in keratinocytes. 1-36. (2001).
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