National Heart & Lung Institute (NHLI)

NHLI Scholarships

  • Man and women in lab setting

National Institute for Health Research (NIHR) Health Protection Research Unit (HPRU) in Respiratory Infections

3yr PhD NHLI Funded studentship commencing in October 2015

The natural history of RSV infection as revealed by viral strain variation

Applications are invited from candidates with a Master’s degree (or equivalent) in Biological Sciences or a related discipline, for a 3 year PhD studentship to investigate “The natural history of RSV infection as revealed by viral strain variation”.

The project will be supported by the NIHR HPRU in Respiratory Infections at Imperial College London. Our mission is to support Public Health England (PHE) by creating a centre-of-excellence to design, conduct and share internationally leading multi-disciplinary research aimed at protecting and improving the public’s health.

Respiratory Syncytial Virus (RSV) is a virus infecting the lungs and airways. In young children and older adults, it frequently leads to severe illness (such as bronchiolitis and pneumonia) and is second only to influenza in this respect. The project will use a comprehensive biobank of human clinical samples from volunteers experimentally infected with RSV, naturally infected patients and national chronic obstructive pulmonary disease (COPD) studies to evaluate viral evolution. The project will aim to define the role of viral sequence evolution in determining location of viral infection (upper vs lower airways), infection time course, immune response and viral persistence as seen in COPD sufferers. The outcome of this research will inform public health services and policy the UK.

The studentship will be funded for 3 years with a tax-free bursary of £17,500 per annum. Tuition fees at the Home/EU rate will also be paid.

The student will primarily work within the group of Professor Peter Openshaw based in the Respiratory Infections Section of the National Heart and Lung Institute, Imperial College London. The project will be supervised by Professor Peter Openshaw (INHLI) and Dr Maria Zambon (PHE), and co-supervised by Dr Christopher Chiu (NHLI). The project will also be in collaboration with Professor Jadwiga Wedzicha (INHLI), who has a major interest in the role of bacterial and viral infection in COPD exacerbations.

The NIHR HPRU in Respiratory Infections is hosted by the National Heart and Lung Institute and provides an exciting environment, with state of the art facilities and excellent opportunities for PhD student training including research seminars and journal clubs. In addition, it provides extensive collaborative opportunities with research partners.

All students will belong to Imperial’s Graduate School, which provides a comprehensive Professional Skills Programme and has received the Times Higher Award for Outstanding Support for Early Careers Researchers in 2006 and 2008.

How to Apply

Applicants must hold, or expect to obtain, a first or upper second-class undergraduate degree or UK equivalent, along with a Masters, both in an appropriate subject from a recognised academic institution. To apply please send a CV, a one page personal statement, and the names and addresses of at least two academic referees to Melanie Rees-Roberts by email on melanie.rees-roberts@imperial.ac.uk.

Please note that candidates must fulfil College admissions criteria.

Application deadline: 4 September 2015, 5pm

Website: http://www1.imperial.ac.uk/hprurespiratoryinfections/ 

Committed to equality and valuing diversity. NHLI is also an Athena Silver SWAN Award winner and Imperial a Stonewall Diversity Champion.

4BBSRCyr PhD BBSRC-Industrial CASE partnership studentship commencing in Autumn 2015

Role of IL-6 and gp130 in maintenance of germinal centre integrity

Applications are invited from candidates with a Master’s degree (or equivalent) in Biological Sciences or a related discipline, for a 4 year PhD studentship to investigate the “Role of IL-6 and gp130 in maintenance of germinal centre integrity” carried out in partnership with MedImmune, the worldwide biologics research and development arm of AstraZeneca.

T follicular helper cells (TFH) are critical to the generation of high affinity antibody within germinal centres. This project takes cutting-edge in vivo and in vitro approaches to investigate the role of the of IL-6, and other gp130 cytokines signalling via the gp130 cytokine receptor, in regulating TFH development and function, compared to other CD4+ T cell subsets. The project will involve the use of in vitro and in vivo model systems and techniques including flow cytometry, imaging and molecular techniques including transcriptomics and/or gene silencing.

The studentship will be funded for 4 years with a tax free bursary in excess of £19,500 per annum. Tuition fees at the Home/EU rate will also be paid.

The student will work within the group of James Harker. The group is based within the Inflammation, Repair and Development section of the National Heart and Lung Institute, Imperial College London, at the South Kensington Campus, with approximately 3-6 months spent at MedImmune’s site in Cambridge.

The National Heart and Lung Institute provides an exciting environment, with state of the art facilities and excellent opportunities for PhD student training including research seminars and journal clubs. In addition, the institute provides extensive collaborative opportunities with other research groups.

All students will belong to Imperial’s Graduate School which provides a comprehensive Professional Skills Programme and has received the Times Higher Award for Outstanding Support for Early Careers Researchers in 2006 and 2008.

How to Apply

Applicants must hold, or expect to obtain, a first or upper second-class undergraduate degree or UK equivalent, along with a Masters, both in an appropriate subject from a recognised academic institution. To apply please send a CV, a one page personal statement, and the names and addresses of at least two academic referees to James Harker by email on j.harker@imperial.ac.uk.  Please note that candidates must fulfil College admissions criteria.

Application deadline: 5pm, 18 September 2015

Website: http://www.imperial.ac.uk/people/j.harker 

Committed to equality and valuing diversity. NHLI is also an Athena Silver SWAN Award winner and Imperial a Stonewall Diversity Champion.

CF Trust logo3yr PhD funded through the Cystic FibrosisTrust - starting between October 2015 and January 2016

Causal mechanisms driving growth and nutrition in early cystic fibrosis

Applications are invited from candidates with a Master’s degree (or equivalent) in Medical Statistics or Epidemiology or a related discipline, for a 3 year PhD studentship to investigate growth and nutrition in children who have cystic fibrosis.

This project will use data from cystic fibrosis registries in the UK, Canada and Denmark. Candidates will use and develop novel methods for longitudinal growth curve analysis to identify differences in growth trajectories between children with cystic fibrosis, identify factors that may explain such differences and determine whether these differences influence long term prognosis.

The studentship will be funded for 3 years with a tax free bursary of £22,278 per annum. Tuition fees at the Home/EU rate will also be paid.

The studentship has been made possible by a Strategic Research Centre (SRC) grant from the Cystic Fibrosis Trust (CF-EpiNet; Harnessing Data to Improve Lives) and is a collaboration between epidemiologists, statisticians, economists and clinicians working across 6 universities. The studentship will be based within the group of Professors Deborah Jarvis and Paul Cullinan at the National Heart and Lung Institute, Imperial College London, at the Royal Brompton Campus. Work will be co-supervised by Dr Sanja Stanojevic at the University of Toronto.

The National Heart and Lung Institute provides an exciting environment, with state of the art facilities and excellent opportunities for PhD student training including research seminars and journal clubs. In addition, the institute provides extensive collaborative opportunities with other research groups.

All students will belong to Imperial’s Graduate School which provides a comprehensive Professional Skills Programme and has received the Times Higher Award for Outstanding Support for Early Careers Researchers in 2006 and 2008.

How to Apply

Applicants must hold, or expect to obtain, a first or upper second-class undergraduate degree or UK equivalent, along with a Masters, both in an appropriate subject from a recognised academic institution. To apply please send a CV, a one page personal statement, and the names and addresses of at least two academic referees to Deborah Jarvis by email on d.jarvis@imperial.ac.uk.

Please note that candidates must fulfil College admissions criteria.

Application deadline: 5pm, 18 September 2015

Website: http://www.imperial.ac.uk/people/d.jarvis

Committed to equality and valuing diversity. NHLI is also an Athena Silver SWAN Award winner and Imperial a Stonewall Diversity Champion.

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Committed to equality and valuing diversity.
We are also an Athena Silver SWAN Award winner and a Stonewall Diversity Champion.

 

Stonewall Diversity Champion