Infectious Disease Epidemiology
The Department carries out world class research into a wide variety of infectious diseases and pathogens, including AIDS and HIV, SARS and pandemic influenza, the Transmissible Spongiform Encephalopathies (e.g. BSE, Scrapie and vCJD), drug-resistant bacteria (e.g. MRSA) and parasites, childhood viral and bacterial diseases, emerging fungal infections, the epidemic viral infections of livestock (e.g. FMD), parasitic helminth infections and bioterrorism.
The staff in the Department have a broad range of scientific skills including molecular biology, immunology, molecular epidemiology, population genetics, mathematical biology, statistics, demography and clinical medicine. These skills are being applied to many problems in the biology, epidemiology, evolution and control of infectious disease. In many cases the research is of direct relevance to public health policy formulation and risk assessment, both in the UK and internationally.
Given below are generic titles describing potential areas of research within the Department of Infectious Disease Epidemiology. These opportunities are currently unfunded.
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Modelling the evolution of drug resistance in HIV-1 infection and the study of how best to control its establishment within the treated patient.
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The role of different vector-parasite combinations in the outcome of programmes for the control of filarial infections.
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Host choice by disease vectors.
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Studies on the population biology of human onchocerciasis.
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Trachoma transmission and control.
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River blindness: infection, morbidity, and mortality in the Onchocerciasis Control Programme area in West Africa.
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Population biology of parasitic nematodes in Bangladesh: a reinfection study.
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Understanding the role of different commerical sex work topology on the spread of HIV/AIDS in developing countries.
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The potential impact of HPV vaccine in the prevention of types 16/18/6/11 infections, cervical cancer and warts in Canada.
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Modelling the impact of potential imperfect HIV vaccine among the homosexual community in Canada.
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Monitoring and evaluation of the Avahan project in India: impact assessment and cost effectiveness analyses using enhanced surveillance methods and mathematical modelling of HIV transmission dynamics.
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Development of a mathematical Modelling platform for Efficacy Trials.
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Control of ebola and gorilla conservation - statistical insights into transmission and the success of interventions.
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Statistical aspects of infectious disease epidemiology.
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From influenza to HIV: The epidemiology, evolution and control of emerging viral pathogens.
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Modelling the global evolution of HIV.
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The landscape genetics of global HIV -associated opportunistic disease.
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Modelling the impact of climate change on Emerging Infectious Diseases.
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Modelling pneumococcal evolution in response to serotype specific vaccines.
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Bacterial genetics: a synthesis of epidemiology and population genetics.
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The epidemiology and control of syphilis.
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The epidemiology of blood bourne infections in networks of injecting drug users.
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Screening and contact tracing in the control of bacterial STIs.
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Stochastic models of macroparasite infectious diseases and cancer.
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Epidemiological spatial and population genetic modelling of parasitic transmission and control.
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Exploration of syphilis epidemiology in the UK: endemic disease, outbreaks and social networks.
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Replacement, reduction, refinement in the Schistosoma system.
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Population and evolutionary biology of bacterial pathogens.
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