National Heart & Lung Institute (NHLI)

Genomic Medicine

Professor Miriam Moffatt, Head of Section 

The Genomic Medicine Section is researching asthma, atopic dermatitis, the genetics of COPD, and the application of genomic technologies to the study of airway diseases.

We wish to identify all of the common genetic variants underlying asthma, eczema and COPD. This will be achieved by whole genome linkage disequilibrium mapping of large numbers of cases, controls, and families. We also wish to use genomics to discover the global picture of gene and protein expression by cells implicated in airway disease. These will include airway epithelial cells, macrophages, dendritic cells, and peripheral blood lymphocytes. The main tool for this research will be RNA microarray analyses.

Research groups

Professor Bill Cookson and Professor Miriam Moffatt - Molecular Genetics and Genomics
Professor Anne Bowcock - Genetics and Genomics of Cancer and Inflammation
Professor Michael Lovett - Genome Technology and Systems Biology

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