Genomics of Common Disease
The Department of Genomics of Common Disease comprises a group of scientists studying the genetics of human multifactorial diseases, particularly type 2 diabetes and obesity.
Major research goals:
- To identify rare and frequent genetic variants that influence risk of common diseases, or related quantitative phenotypes.
- To determine the cellular and physiological functions of susceptibility genes in the normal and pathological states, including the nature of their interactions with other susceptibility genes and environmental factors.
- To develop novel technological and analytic approaches for investigation of genetic factors influencing human diseases
Ultimately, our research aims are to advance our understanding of the patho-physiological mechanisms that underlie the development of these diseases. This will lay the foundation for personalised medicine, leading to:
- improved medical treatment for patients
- targeted lifestyle or pharmaceutical preventative strategies for high-risk individuals.