Structural organisation of the antithrombin gene and protein

The gene structure illustrates the coding regions (exons, numbered 1-6), the Alu repeat regions (arrow heads), and several of the polymorphic sites (L, the 76bp dimorphism at -276; P, Pst I site at 7626; N, the Nhe I site at 7987; D, Dde I site at 9893; (ATT)n, the two trinucleotide polymorphic sites at 8136 and 9289-see Polymorphisms/sequence variations.

Structural organisation of the antithrombin gene

Structural organisation of the antithrombin protein

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